keyword
https://read.qxmd.com/read/38533518/borderline-case-in-reconstructive-plastic-surgery-of-the-lower-limb-treated-with-bone-drilling-and-use-of-dermal-regeneration-template
#21
Vincenzo Verdura, Luigi Cagiano, Marcello Molle, Pasquale Bisceglia, Nicola Fini, Luigi Annacontini, Vincenzo Mazzarella, Domenico Parisi, Aurelio Portincasa
The traumatic pathology of the lower limb represents a very complex branch of medicine, which, despite the wide presence of guidelines, aimed at regulating the various therapeutic procedures, and is still greatly influenced by random variables and by the multiple responses to treatments. In this report, we present our experience with a borderline case, where the timing of the trauma and the patient's characteristics made it difficult to use the most recommended procedures in trauma management.
March 2024: Plastic and Reconstructive Surgery. Global Open
https://read.qxmd.com/read/38532678/-brain-fog-a-concept-analysis
#22
JOURNAL ARTICLE
Chi-Wen Pan, Wei-Fang Wang
Brain fog is a symptom that has gained increasing attention worldwide since the start of the COVID-19 pandemic, as patients affected by COVID-19 may experience cognitive dysfunction, colloquially known as brain fog, for a period of time after recovery. Brain fog affects activities of daily living and work performance and has the potential to negatively impact society and the economy. However, a clear definition and concept analysis of brain fog is lacking in the literature. In this article, a concept analysis of brain fog is conducted using Walker and Avant's concept analysis steps to verify the source and definition of brain fog, clarify related concepts similar to brain fog, and establish the defining attributes, antecedents, and consequences of this condition...
April 2024: Hu Li za Zhi the Journal of Nursing
https://read.qxmd.com/read/38530956/multicenter-prospective-cohort-study-of-neoadjuvant-chemotherapy-for-borderline-resectable-pancreatic-cancer-ypb-001
#23
JOURNAL ARTICLE
Hiroto Matsui, Tatsuya Ioka, Tsuyoshi Takahashi, Toru Kawaoka, Yoshinari Maeda, Noboru Yahara, Hidefumi Kubo, Taku Nishimura, Toshihiro Inokuchi, Eijiro Harada, Yoshitaro Shindo, Yukio Tokumitsu, Masao Nakajima, Taro Takami, Katsuyoshi Ito, Hidekazu Tanaka, Kimikazu Hamano, Hiroaki Nagano
OBJECTIVES: The present multicenter prospective observational study investigated the effectiveness and safety of neoadjuvant chemotherapy (NAC) for patients with borderline resectable pancreatic cancer (BRPC) and those with RPC contacting major vessels, with respect to a historical control of upfront surgery. MATERIALS AND METHODS: Patients with BRPC and RPC contacting major vessels were prospectively registered and administered NAC with durations and regimens determined by the corresponding treating physician...
March 4, 2024: Pancreas
https://read.qxmd.com/read/38529526/the-use-of-optical-coherence-tomography-oct-and-oct-angiography-in-borderline-personality-disorder-compared-to-health-control-subjects
#24
JOURNAL ARTICLE
Bei Xu, Fangling Li, Zhejia Zhang, Qian Xiao
BACKGROUND: Optical coherence tomography (OCT) or OCT angiography (OCTA) has been investigated in few research studies of psychiatric disorders. No research has been done using OCT or OCTA in patients with borderline personality disorder (BPD). METHODS: OCTA measured foveal avascular zone (FAZ), macular vessel density (MVD), and peripapillary vessel density (PVD). OCT measured the peripapillary retinal fiber layer (RNFL) and central retinal thickness (CRT). The study utilized the Ottawa Self-Injury Inventory, Hamilton Anxiety Rating Scale (HAMA), and Global Assessment of Functioning (GAF) to assess the symptom characteristics of individuals with BPD...
March 2024: CNS Neuroscience & Therapeutics
https://read.qxmd.com/read/38529097/ipvaw-male-perpetrators-convicted-in-spain-a-typology-and-characterization-based-on-latent-class-analysis
#25
JOURNAL ARTICLE
Iria de la Osa-Subtil, Andrés Arias Astray, Pedro V Mateo Fernandez, María J de Dios-Duarte
INTRODUCTION: Men who assault their partners present deficits in the social skills necessary for adequate interpersonal interaction. Not all of them have the same difficulties, thus they do not constitute a homogeneous group. Various studies have proposed different typologies of abusers based on their sociodemographic characteristics, criminal history, intensity and extent of violent or psychopathological traits. The majority of these investigations have been conducted in community samples, prompting the question of their validity in samples of men convicted of gender violence...
2024: Frontiers in Psychology
https://read.qxmd.com/read/38527014/prediction-of-homologous-recombination-deficiency-from-oncomine-comprehensive-assay-plus-correlating-with-sophia-ddm-hrd-solution
#26
JOURNAL ARTICLE
Jun Kang, Kiyong Na, Haeyoun Kang, Uiju Cho, Sun Young Kwon, Sohyun Hwang, Ahwon Lee
OBJECTIVE: Poly(ADP-ribose) polymerase (PARP) inhibitors are used for targeted therapy for ovarian cancer with homologous recombination deficiency (HRD). In this study, we aimed to develop a homologous recombination deficiency prediction model to predict the genomic integrity (GI) index of the SOPHiA DDM HRD Solution from the Oncomine Comprehensive Assay (OCA) Plus. We also tried to a find cut-off value of the genomic instability metric (GIM) of the OCA Plus that correlates with the GI index of the SOPHiA DDM HRD Solution...
2024: PloS One
https://read.qxmd.com/read/38526405/prodromal-or-factitious-psychosis-a-cautionary-tale-in-the-era-of-increasing-social-media-use-by-vulnerable-individuals
#27
JOURNAL ARTICLE
Leo Bastiaens, Stephanie Cristofano-Casella, Jesse Bastiaens
Research on the prodromal phase of schizophrenia has been ongoing for several decades and, more recently, findings from this research are being incorporated into everyday psychiatric practice, such as the use of interviews to evaluate prodromal symptomatology. This evolution is happening in the midst of an explosion of social media use by teenagers and young adults, increasing the exposure of youth to portrayals of psychiatric experiences. For example, reports from around the world of "TIK-TOK tics" emphasize the role of social media in the "creation" of psychiatric symptoms...
March 1, 2024: Journal of Psychiatric Practice
https://read.qxmd.com/read/38524745/latent-class-of-depressive-symptoms-of-and-its-determinants-a-cross-sectional-study-among-iranian-university-students
#28
JOURNAL ARTICLE
Forugh Aleebrahim, Zahra Heidari, Shahla Yousefnejad, Gholamreza Kheirabadi, Mohammad Javad Tarrahi
BACKGROUND: According to the report of the World Health Organization, mental disorders are one of the 10 most important causes of disability in the world. This study was conducted with the aim of determining the number and frequency of latent classes of depression and its determinants in Isfahan university of medical students. MATERIALS AND METHODS: A total of 1408 medical students from Isfahan University of Medical Sciences, Iran, were enrolled in the study in 2017...
2024: Journal of Research in Medical Sciences: the Official Journal of Isfahan University of Medical Sciences
https://read.qxmd.com/read/38524666/an-attenuated-adult-case-of-aadc-deficiency-demonstrated-by-protein-characterization
#29
Giovanni Bisello, Christiaan G J Saris, Rossella Franchini, Marcel M Verbeek, Michel A A P Willemsen, Massimiliano Perduca, Mariarita Bertoldi
A case of an adult with borderline AADC deficiency symptoms is presented here. Genetic analysis revealed that the patient carries two AADC variants (NM_000790.3: c.1040G > A and c.679G > C) in compound heterozygosis, resulting in p.Arg347Gln and p.Glu227Gln amino acid alterations. While p.Arg347Gln is a known pathogenic variant, p.Glu227Gln is unknown. Combining clinical features to bioinformatic and molecular characterization of the AADC protein population of the patient (p.Arg347Gln/p...
June 2024: Molecular Genetics and Metabolism Reports
https://read.qxmd.com/read/38524185/exploring-blood-lipids-immunity-associations-following-hbv-vaccination-evidence-from-a-large-cross-sectional-study
#30
JOURNAL ARTICLE
Qian Yang, Benhua Li, Tiankuo Luan, Xiaoyu Wang, Bixia Duan, Chengcheng Wei, Shi Chen
INTRODUCTION: Serological responses following hepatitis B vaccination are crucial for preventing hepatitis B (HBV). However, the potential relationship between serum lipid levels and immunity from HBV vaccination remains poorly understood. METHODS: In this study, we conducted an analysis of the National Health and Nutrition Examination Survey (NHANES) data spanning from 2003 to 2016. Multivariable weighted logistic regression models, generalized linear analysis, stratified models, smooth curve fitting, segmentation effect analysis and sensitivity analysis were utilized to assess the relationships...
2024: Frontiers in Cellular and Infection Microbiology
https://read.qxmd.com/read/38523735/risk-factors-for-development-of-cirrhosis-in-chronic-viral-hepatitis-b-patients-who-had-persistent-viral-suppression-with-antiviral-therapy
#31
JOURNAL ARTICLE
Soe T Maung, Pakanat Decharatanachart, Sombat Treeprasertsuk, Roongruedee Chaiteerakij
BACKGROUND AND AIMS: Chronic viral hepatitis B (CHB)-infected patients occasionally develop cirrhosis despite having persistent viral suppression with antiviral therapy. We aimed to identify risk factors for developing cirrhosis in hepatitis B virus (HBV)-suppressed patients. METHODS: We conducted a case-control study involving 120 noncirrhotic CHB-infected patients achieving viral suppression with antiviral treatment, with 40 cases developing cirrhosis and 80 age-, sex-, and Fibrosis-4 (FIB-4)-matched controls...
2024: Journal of Clinical and Experimental Hepatology
https://read.qxmd.com/read/38523413/a-comprehensive-analysis-of-age-of-onset-and-cumulative-incidence-of-mental-disorders-a-danish-register-study
#32
JOURNAL ARTICLE
Christoffer Beck, Carsten Bøcker Pedersen, Oleguer Plana-Ripoll, Søren Dalsgaard, Jean-Christophe Philippe Debost, Thomas Munk Laursen, Katherine Louise Musliner, Preben Bo Mortensen, Marianne Giørtz Pedersen, Liselotte Vogdrup Petersen, Zeynep Yilmaz, John McGrath, Esben Agerbo
BACKGROUND: The age of onset (AOO), incidence and cumulative incidence of mental disorders are critical epidemiological measures, providing essential insights into the development and course of these disorders across the lifespan. This study aims to provide up-to-date estimates of the AOO, age-specific incidence, and cumulative incidence for a comprehensive range of mental disorders using data from Danish registers. METHODS: We conducted a follow-up study encompassing all Danish residents from January 1, 2004, to December 31, 2021, totaling 91,613,465 person-years...
March 24, 2024: Acta Psychiatrica Scandinavica
https://read.qxmd.com/read/38523025/-effectiveness-of-psychotherapy-on-dissociative-symptoms-in-adult-populations-a-prisma-systematic-review
#33
JOURNAL ARTICLE
Camille Aujoulat, Alexis Vancappel, Géraldine Tapia
INTRODUCTION: Dissociation is a psychological process in reaction to threat which can be found in many psychiatric conditions. Dissociative symptoms can become very disabling, whether in daily life or in care. Nevertheless, few studies seem to have examined the efficacy of psychotherapy on the latter and its relevance as a therapeutic target. METHOD: A systematic review of the literature (PRISMA) on the efficacy of psychotherapy on dissociative symptoms in adults with mental disorders was conducted...
March 23, 2024: L'Encéphale
https://read.qxmd.com/read/38522867/endocardial-fibroelastosis-resection-when-it-works-and-when-it-does-not
#34
REVIEW
Gregor Gierlinger, Sitaram M Emani
Endocardial fibroelastosis (EFE) is a thickening of the endocardial layer by accumulation of collagen and elastic fibers. Endothelial to mesenchymal transformation is proposed to be the underlying mechanism of formation. Although EFE can occur in both right and left ventricles, this article will focus on management of left ventricular EFE. Through its fibrous, nonelastic manifestation EFE restricts the myocardium leading to diastolic and systolic ventricular dysfunction and prevents ventricular growth in neonates and infants...
2024: Seminars in Thoracic and Cardiovascular Surgery. Pediatric Cardiac Surgery Annual
https://read.qxmd.com/read/38522359/evaluation-of-the-follicular-patterned-thyroid-lesions-based-on-the-who-2022-criteria-with-an-emphasis-on-the-grey-zone-lesions
#35
JOURNAL ARTICLE
Sunayana Misra, Shashi Dhawan, Sonia Badwal, Arupparna Sengupta, Aanchal Khosla, Sangeet Kumar Agarwal, Seema Rao
Follicular-patterned thyroid nodules (FPTN) are classified byWHO-2022 into benign, borderline and malignant categories. There are however, grey-zone lesions that pose a diagnostic challenge due to ambiguity in defining criteria and inter-observer variability. WHO-2022 has enumerated specific diagnostic criteria for these lesions. Accurate categorization of morphologically similar TNs is vital to reduce overtreatment of indolent lesions. In this study, we have reclassified FPTNs according to WHO-2022 criteria, emphasizing on grey-zone lesions...
February 14, 2024: Annals of Diagnostic Pathology
https://read.qxmd.com/read/38522259/the-course-of-borderline-personality-disorder-from-adolescence-to-early-adulthood-a-5-year-follow-up-study
#36
JOURNAL ARTICLE
Mie Sedoc Jørgensen, Lise Møller, Sune Bo, Mickey Kongerslev, Lene Halling Hastrup, Andrew Chanen, Ole Jakob Storebø, Stig Poulsen, Emma Beck, Erik Simonsen
BACKGROUND: Studies of the medium- to long-term clinical and functional course for treatment-seeking adolescents with borderline personality disorder (BPD) are lacking. This study aims to outline the psychopathological and functional status of participants, five years after being diagnosed with BPD during adolescence. METHODS: Participants were originally enrolled in a randomized clinical trial that compared mentalization-based group treatment with treatment as usual for adolescents with BPD...
March 21, 2024: Comprehensive Psychiatry
https://read.qxmd.com/read/38520460/association-of-pulmonary-artery-pressures-with-mortality-in-adults%C3%A2-with%C3%A2-reduced-left-ventricular-ejection%C3%A2-fraction
#37
JOURNAL ARTICLE
Seshika Ratwatte, Simon Stewart, Geoff Strange, David Playford, David S Celermajer
BACKGROUND: The independent effect of pulmonary hypertension (PHT) severity on mortality in those with reduced left ventricular ejection fraction (LVEF) is not well known. OBJECTIVES: The authors aimed to examine the prognostic impact of increasingly elevated pulmonary pressures in a large clinical cohort of adults with reduced LVEF. METHODS: The authors analyzed data from the National Echocardiography Database of Australia, a large clinical registry linking routine echocardiographic investigations to mortality...
March 12, 2024: JACC. Heart Failure
https://read.qxmd.com/read/38518456/pressure-ulcer-risk-assessment-in-the-icu-is-it-time-for-a-more-objective-measure
#38
JOURNAL ARTICLE
Natalie L McEvoy, Declan Patton, Gerard F Curley, Zena Moore
BACKGROUND: The Braden scale, one of the most widely used risk assessment tools is often criticized when used in the Intensive Care Unit. Most patients in the Intensive Care Unit are at risk of pressure ulcer development meaning that the Braden score will usually indicate high risk for these patients. This study set out to determine the correlation between Sub-Epidermal Moisture measurements and Braden scores among Intensive Care Unit patients. METHODS: This study employed an observational research design...
March 21, 2024: Intensive & Critical Care Nursing: the Official Journal of the British Association of Critical Care Nurses
https://read.qxmd.com/read/38517214/association-between-helminth-infection-and-allergic-disorders-among-children-in-batu-ethiopia
#39
JOURNAL ARTICLE
Sosina Walelign, Mheret Tesfaye, Geremew Tasew, Kassu Desta, Aster Tsegaye, Bineyam Taye
BACKGROUND: Helminths are potent immunomodulators and in their chronic infection state they may protect against allergy-related disease and atopy. However, they are also known for inducing allergic conditions. This study aimed to assess the association between helminths,  atopy and allergic conditions. METHODS: A total of 461 school children participated in this cross-sectional study. Data on allergic symptoms and a range of confounding variables was gathered from parents via an interviewer-led questionnaire...
March 2024: Immunity, Inflammation and Disease
https://read.qxmd.com/read/38515571/trends-in-survival-of-ovarian-clear-cell-carcinoma-patients-from-2000-to-2015
#40
JOURNAL ARTICLE
Bing-Qian Tian, Shu-Wen Wang, Jing-Ying Xu, San-Gang Wu, Juan Zhou
PURPOSE: To analyze changes in survival outcomes in patients with ovarian clear cell carcinoma (OCCC) treated consecutively over a 16-year period using a population-based cohort. METHODS: We conducted a retrospective analysis of OCCC from 2000 to 2015 using data from the Surveillance, Epidemiology, and End Results (SEER) program. The ovarian cancer-specific survival (OCSS) and overall survival (OS) were analyzed according to the year of diagnosis. Joinpoint Regression Program, Kaplan-Meier analysis, and multivariate Cox regression analyses were used for statistical analysis...
2024: Frontiers in Oncology
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