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Acute coronary syndromes

Xinyu Hu, Shijiao Cheng, Yuehui Yin, Lin Ning, Liquan Xiang, Yinpin Zhou
BACKGROUND: Supplemental oxygen has been commonly used in the cases of acute coronary syndrome (ACS); however, recent evidence suggests that high-concentration oxygen supplementation and hyperbaric oxygen in ACS patients are associated with adverse cardiovascular effects. OBJECTIVE: The purpose of this article is to systematically review the role of supplemental oxygen therapy in normoxemic patients with ACS. METHODS: A search for randomized controlled trials before November 2017 in biomedical databases was performed, and a total of 6 eligible studies with 7508 participants were identified...
July 18, 2018: Journal of Cardiovascular Nursing
Emrah Ermiş, Hakan Uçar, Selami Demirelli, Emrah İpek, Mustafa Gür, Murat Çaylı
OBJECTIVE: Many interventional cardiologists are concerned about the risk of side branch (SB) loss during main vessel (MV) stenting in complex bifurcation lesions. Therefore, novel techniques are required to reduce the risk of SB occlusion. The jailed semi-inflated balloon technique (JSBT) is one of these techniques. This article is a description of clinical experience with SB patency assessment using the JSBT. METHODS: A total of 64 patients with 82 distinct coronary bifurcation lesions underwent percutaneous coronary intervention (PCI) via JSBT at this institution...
July 2018: Türk Kardiyoloji Derneği Arşivi: Türk Kardiyoloji Derneğinin Yayın Organıdır
Emanuel Harari, Alon Eisen
No abstract text is available yet for this article.
June 2018: Journal of Thoracic Disease
Tatiana Duarte, Sara Gonçalves, Catarina Sá, Rita Rodrigues, Rita Marinheiro, Marta Fonseca, Filipe Seixo, Rui Caria
BACKGROUND: Iron metabolism disorders have been associated with an increased risk of cardiovascular events. However, the prognostic impact on patients (pts) with acute coronary syndrome (ACS) has yet to be clarified. OBJECTIVE: To determine the prognostic value of serum iron and ferritin levels in pts with ACS in the short and long-term. METHODS: Consecutive pts admitted to a coronary care unit with a diagnosis of ACS, for a period of 2 years, were evaluated...
July 16, 2018: Arquivos Brasileiros de Cardiologia
Krzysztof L Bryniarski, Erika Yamamoto, Tomoyo Sugiyama, Lei Xing, Hang Lee, Ik-Kyung Jang
AIMS: Prevalence of coronary artery disease as well as cardiac mortality varies between Asian and White patients. However, the link between race and plaque characteristics in patients with coronary artery disease remains largely unexplored. Thus, we aimed to investigate the detailed culprit plaque characteristics between East Asian and White patients using optical coherence tomography. PATIENTS AND METHODS: A total of 101 East Asians were matched to 101 White patients...
July 16, 2018: Coronary Artery Disease
Sharon R Lewis, Michael W Pritchard, Oliver J Schofield-Robinson, Phil Alderson, Andrew F Smith
BACKGROUND: Antiplatelet agents are recommended for people with myocardial infarction and acute coronary syndromes, transient ischaemic attack or stroke, and for those in whom coronary stents have been inserted. People who take antiplatelet agents are at increased risk of adverse events when undergoing non-cardiac surgery because of these indications. However, taking antiplatelet therapy also introduces risk to the person undergoing surgery because the likelihood of bleeding is increased...
July 18, 2018: Cochrane Database of Systematic Reviews
Hideaki Matsuura, Akira Yamada, Kunihiko Sugimoto, Keiko Sugimoto, Masatsugu Iwase, Takashi Ishikawa, Junichi Ishii, Yukio Ozaki
Purpose: The ratio of the left atrial volume index (LAVI) and late diastolic mitral annular velocity (A') is a useful echocardiographic index for identifying advanced left ventricular (LV) diastolic dysfunction in patients with dyspnoea. We investigated the clinical implications and prognostic value of the aforementioned ratio (LAVI/A') in patients with ST elevation (STE) or non-STE (NSTE) acute coronary syndrome (ACS). Methods: We studied 212 patients with ACS...
2018: Heart Asia
Thiruvelselvan Ponnusamy, Srikanth K Venkatachala, Manjunatha Ramanjappa, Vijay V Kakkar, Lakshmi A Mundkur
Objective: Atherosclerosis is an autoimmune condition and the underlying cause of coronary artery disease (CAD). Circulating antibodies to self-antigens can have a pathogenic or protective function in atherosclerosis. The objective of the study was to understand the association of autoantibody levels with CAD and its correlation with circulating immune cells. Methods: We assessed antigen concentration and antibodies to apolipoprotein B (ApoB) and heat shock protein (HSP)60 by ELISA in 252 acute coronary syndromes (ACS), 112 patients with stable angina (SA) and 203 healthy controls from Indian population...
2018: Heart Asia
Batur Gonenc Kanar, Kursat Tigen, Halil Atas, Altug Cincin, Beste Ozben
A prosthetic valve thrombosis (PVT), which is a potentially fatal complication, refers to the presence of non-infective thrombotic material on a prosthetic valve apparatus, interfering with its function. Possible complications of a PVT include transient neurologic embolic events, cardiac arrest due to a stuck valve prosthesis, and cardio-embolic myocardial infarction (MI). The choice of treatments, including a redo surgery, a percutaneous coronary intervention (PCI), and a fibrinolysis with PVT or MI dosages, depends on the patient's clinical and hemodynamic status and thrombotic burden involving the prosthetic valve and surrounding tissues...
June 19, 2018: American Journal of Emergency Medicine
Rishi Sethi, Puneet Gupta, Akshyaya Pradhan, Mahim Saran, Bonnie R K Singh, Pravesh Vishwakarma, Monika Bhandari, Gaurav Chaudhary, Sharad Chandra, Akhil Sharma, S K Dwivedi, V S Narain
BACKGROUND: Owing to the growing evidence that the pathophysiology of obstructive sleep apnoea (OSA) and metabolic syndrome (MS) overlap considerably and both adversely impact cardiovascular health, we hypothesised that the presence of OSA with MS additively and adversely affect the severity of coronary artery disease (CAD). Exploration and understanding of this may have direct implications for the development of targeted, preventive strategies for CAD. Thus, this prospective study was aimed to determine the prevalence of 'Syndrome Z' in patients of MS who present with an acute coronary event and to correlate it with the angiographic severity of CAD in these patients...
June 23, 2018: Heart, Lung & Circulation
Hideya Yamamoto, Yasuki Kihara, Toshiro Kitagawa, Norihiko Ohashi, Eiji Kunita, Yoshitaka Iwanaga, Kazuhiro Kobuke, Shunichi Miyazaki, Tomohiro Kawasaki, Shinichiro Fujimoto, Hiroyuki Daida, Takashi Fujii, Aki Sato, Tomokazu Okimoto, Sachio Kuribayashi
BACKGROUND: Coronary computed tomography angiography (CCTA) not only provides information regarding luminal stenoses but also allows for visualization of mural atheromatous changes (coronary plaques). OBJECTIVE: We sought to elucidate whether plaques seen on CCTA enable prediction of 2-year outcomes in patients with suspected and known coronary artery disease (CAD). METHODS: Of 3015 patients who underwent CCTA, the images and 2-year clinical courses of 2802 patients were independently analyzed...
July 7, 2018: Journal of Cardiovascular Computed Tomography
Xiao-Yu Zhou, Jing Xu
It is estimated that 15% of traffic accidents cause trauma to large vessels. In about 70%-95% of cases, aortic rupture took place in the distal ligament of the left subclavian artery, whereas in the remaining cases rupture occurred in the ascending aorta above the aortic valve. Trauma to the aortic sinus and coronary arteries is rarely found in traffic accident victims. Therefore, coronary artery trauma is often misdiagnosed as coronary atherosclerotic heart disease. The present case is a 42 years old male who survived from a traffic accident...
June 28, 2018: Chinese Journal of Traumatology, Zhonghua Chuang Shang za Zhi
Codie R Rouleau, Kathryn M King-Shier, Lianne M Tomfohr-Madsen, Simon L Bacon, Sandeep Aggarwal, Ross Arena, Tavis S Campbell
OBJECTIVES: Cardiac rehabilitation (CR) is an effective treatment for cardiovascular disease, yet many referred patients do not participate. Motivational interviewing could be beneficial in this context, but efficacy with prospective CR patients has not been examined. This study investigated the impact of motivational interviewing on intention to participate in CR. METHODS: Individuals recovering from acute coronary syndrome (n = 96) were randomized to motivational interviewing or usual care, following CR referral but before CR enrollment...
June 26, 2018: Patient Education and Counseling
Yi-Heng Li, Yu-Chen Wang, Yi-Chih Wang, Ju-Chi Liu, Cheng-Han Lee, Chun-Chi Chen, I-Chang Hsieh, Feng-You Kuo, Wei-Chun Huang, Shih-Hsien Sung, Chiung-Zuan Chiu, Jung-Cheng Hsu, Shu-Long Jen, Juey-Jen Hwang, Jiunn-Lee Lin
In Taiwan, the incidence of non-ST segment elevation acute coronary syndrome (NSTE-ACS) continues to increase in recent years. The purpose of this guideline is to help health care professionals in Taiwan to use adequate tests and treatments for management of NSTE-ACS. For rapid diagnosis, in addition to history and physical examination, 0/3 h rapid diagnosis protocol with high sensitivity cardiac troponin assay is recommended in this guideline. Dual antiplatelet and anticoagulation therapies are important parts in the initial treatment...
July 12, 2018: Journal of the Formosan Medical Association, Taiwan Yi Zhi
Jan Pitha
No abstract text is available yet for this article.
July 6, 2018: International Journal of Cardiology
Natale Daniele Brunetti
No abstract text is available yet for this article.
July 10, 2018: International Journal of Cardiology
Melinda B Davis
No abstract text is available yet for this article.
June 30, 2018: Trends in Cardiovascular Medicine
Chang-Zheng Gao, Qian-Qian Ma, Jing Wu, Rui Liu, Fen Wang, Jie Bai, Xiang-Jun Yang, Qiang Fu, Peng Wei
BACKGROUND/AIMS: Acute ST-segment elevation of myocardial infarction (STEMI) is the most severe type of acute coronary syndrome (ACS). Particular attention has been focused on studying the pathogenesis of STEMI, and how to prevent thrombosis, reduce inflammatory reaction, stabilize plaques and improve vascular endothelial functions to preserve the survived myocardium. This study aimed to compare the anti-inflammatory endothelium-protective effects, clinical prognosis, and relevant bleeding risks of ticagrelor versus clopidogrel in patients with STEMI who underwent urgent percutaneous coronary intervention (PCI) and provide certain experimental evidence and a theoretical basis for the selection of safe and effective drugs and their proper dosage, thereby further guiding clinical medication...
July 17, 2018: Cellular Physiology and Biochemistry
Jinggang Xia, Shaodong Hu, Ji Xu, Hengjian Hao, Chunlin Yin, Dong Xu
Background This study aimed to investigate the correlation between glucose fluctuation from self-monitored blood glucose (SMBG) and the major adverse cardiac events (MACE) in diabetic patients with acute coronary syndrome (ACS) during a 6-month follow-up period using the WeChat application. Methods From November 2016 to June 2017, 262 patients with ACS were discharged in a stable condition and completed a 6-month follow-up period. SMBG was recorded using the WeChat application. The patients were divided to a high glucose fluctuation group (H group; n=92) and a low glucose fluctuation group (L group; n=170)...
July 16, 2018: Clinical Chemistry and Laboratory Medicine: CCLM
Gencer Baris, François Mach
Low-density lipoprotein-cholesterol (LDL-C) is a well-accepted causal risk factor for athero-thrombotic cardiovascular disease, as demonstrated in large epidemiological studies, including Mendelian randomization data. Several randomized controlled trials and meta-analyzes have shown that lipid lowering therapies, such as statins and more recently the non-statin agents ezetimibe and Proprotein Convertase Subtilisin Kexin type 9 (PCSK9) monoclonal antibodies (mAb), reduce cardiovascular events across a broad range of baseline LDL-C levels...
June 22, 2018: Atherosclerosis
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