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https://www.readbyqxmd.com/read/29160421/longitudinal-study-of-lung-function-in-pregnant-women-influence-of-parity-and-smoking
#1
Luciana Duzolina Manfré Pastro, Miriam Lemos, Frederico Leon Arrabal Fernandes, Silvia Regina Dias Médici Saldiva, Sandra Elisabete Vieira, Beatriz Mangueira Saraiva Romanholo, Paulo Hilário Nascimento Saldiva, Rossana Pulcineli Vieira Francisco
OBJECTIVES: To evaluate pulmonary function in the first and third trimesters of pregnancy and analyze the influence of parity and smoking on spirometry parameters. METHODS: This longitudinal prospective study included a cohort of 120 pregnant women. The inclusion criteria were as follows: singleton pregnancy, gestational age less than 13.86 weeks, and no preexisting maternal diseases. The exclusion criteria were as follows: change of address, abortion, and inadequate spirometry testing...
October 2017: Clinics
https://www.readbyqxmd.com/read/29156548/patient-provider-communication-and-counseling-about-gestational-weight-gain-and-physical-activity-a-qualitative-study-of-the-perceptions-and-experiences-of-latinas-pregnant-with-their-first-child
#2
Ana Cristina Lindsay, Sherrie F Wallington, Mary L Greaney, Marcia M Tavares Machado, Gabriela P De Andrade
Latina women in the United States (U.S.) are disproportionately affected by obesity and are more likely to begin pregnancy overweight and gain excessive weight during pregnancy. The prenatal care period represents a window of opportunity for women to access the healthcare system and receive preventive services, education, nutritional support, and other social services to improve pregnancy outcomes. Excessive gestational weight gain (GWG) has numerous negative short- and long-term consequences for both the mother and newborn...
November 18, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29155742/isolation-of-intact-whole-mouse-mammary-glands-for-analysis-of-extracellular-matrix-expression-and-gland-morphology
#3
Christopher Thompson, Katherine Keck, Abigail Hielscher
The goal of this procedure was to harvest the #4 abdominal mammary glands from female nulliparous mice in order to assess ECM expression and ductal architecture. Here, a small pocket below the skin was created using Mayo scissors, allowing separation of the glands within the subcutaneous tissue from the underlying peritoneum. Visualization of the glands was aided by the use of 3.5x-R surgical micro loupes. The pelt was inverted and pinned back allowing identification of the intact mammary fat pads. Each of the #4 abdominal glands was bluntly dissected by sliding the scalpel blade laterally between the subcutaneous layer and the glands...
October 30, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/29155504/cervical-funneling-or-intra-amniotic-debris-and-preterm-birth-among-nulliparous-women-with-a-midtrimester-cervical-length-less-than-30-mm
#4
George R Saade, Elizabeth A Thom, William A Grobman, Jay D Iams, Brian M Mercer, Uma M Reddy, Alan T N Tita, Dwight J Rouse, Yoram Sorokin, Ronald J Wapner, Kenneth J Leveno, Sean C Blackwell, M Sean Esplin, Jorge E Tolosa, John M Thorp, Steve N Caritis, J Peter VanDorsten
OBJECTIVE: To evaluate whether the presence of cervical funneling or intra-amniotic debris identified in the second trimester is associated with higher rates of preterm birth (PTB) in asymptomatic nulliparous women with a midtrimester cervical length (CL) less than 30 mm (i.e., less than the 10(th) percentile). METHODS: A secondary cohort analysis of a multicenter trial of women between 16 and 22 weeks with a singleton gestation and a CL less than 30 mm by transvaginal ultrasound randomized to either 17-alpha hydroxyprogesterone caproate or placebo...
November 20, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/29155474/visual-biofeedback-using-trans-perineal-ultrasound-during-the-second-stage-of-labor
#5
Yinon Gilboa, Tahl I Frenkel, Yael Schlesinger, Sofie Rousseau, Daniel Hamiel, Reuven Achiron, Sharon Perlman
OBJECTIVES: to assess the obstetrical and psychological effect of visual biofeedback using trans-perineal ultrasound (TPU) during the second stage of labor. METHODS: Visual biofeedback using TPU was performed prospectively during the second stage of labor in twenty-six low risk nulliparous women. Pushing efficacy was assessed by the angle of progression at rest and during pushing efforts before and after observing the ultrasound screen. Obstetrical outcomes included level of perineal tearing, mode of delivery and length of the second stage...
November 20, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/29153691/hypertension-and-patterns-of-induced-labor-at-term
#6
Julia M Bregand-White, Michelle A Kominiarek, Judith U Hibbard
OBJECTIVE: To study patterns of induced labor at term in hypertensive women. STUDY DESIGN: We performed a retrospective cohort study using the Consortium on Safe Labor database; a multicenter study of labor and delivery practices from electronic medical records in 19 hospitals. 55,572 women were studied: 28,254 nulliparas and 27,318 multiparas, undergoing induction of labor at term without a prior cesarean with a singleton vertex live born fetus. Four hypertensive groups were defined: chronic hypertension (n=1164), gestational hypertension (n=1861), preeclampsia (n=1513) and superimposed preeclampsia (n=655), compared to controls (no hypertension, n=50,379)...
October 2017: Pregnancy Hypertension
https://www.readbyqxmd.com/read/29153685/effects-of-delivery-on-maternal-neonatal-irisin-levels-in-normal-and-preeclamptic-pregnant-women
#7
Ashraf A Foda, Engy A Foda
STUDY OBJECTIVE: The aim of this work was to measure the irisin levels in maternal and umbilical cord serums at cesarean section and vaginal delivery. STUDY DESIGN: This is a case-control study conducted at the Obstetric Department of the Mansoura University Hospital, Mansoura University, Egypt. MATERIAL AND METHODS: The 150 nulliparous cases were divided into three groups. MAIN OUTCOME MEASURE: Serum irisin concentrations were assayed by enzyme-linked immunosorbent assay (ELISA) method...
October 2017: Pregnancy Hypertension
https://www.readbyqxmd.com/read/29153659/a-simple-clinical-method-to-identify-women-at-higher-risk-of-preeclampsia
#8
Effie Viguiliouk, Alison L Park, Howard Berger, Michael P Geary, Joel G Ray
An outstanding issue is how to efficiently identify women at high risk of preeclampsia. This retrospective cohort study included 8672 pregnancies at a single centre in Toronto. We tested our simple method - presence vs. absence of≥1 major (pre-pregnancy BMI>30kg/m(2), chronic hypertension, pre-pregnancy diabetes mellitus and assisted reproductive therapy) or≥2 minor (prior stillbirth, age>40years, nulliparity, multifetal pregnancy, chronic kidney disease, and SLE) risk factors for PE. The RR of PE was 8...
October 2017: Pregnancy Hypertension
https://www.readbyqxmd.com/read/29150465/differences-in-optimality-index-between-planned-place-of-birth-in-a-birth-centre-and-alternative-planned-places-of-birth-a-nationwide-prospective-cohort-study-in-the-netherlands-results-of-the-dutch-birth-centre-study
#9
Marieke A A Hermus, Marit Hitzert, Inge C Boesveld, M Elske van den Akker-van Marle, Paula van Dommelen, Arie Franx, Johanna P de Graaf, Jan M M van Lith, Nathalie Luurssen-Masurel, Eric A P Steegers, Therese A Wiegers, Karin M van der Pal-de Bruin
OBJECTIVES: To compare the Optimality Index of planned birth in a birth centre with planned birth in a hospital and planned home birth for low-risk term pregnant women who start labour under the responsibility of a community midwife. DESIGN: Prospective cohort study. SETTING: Low-risk pregnant women under care of a community midwife and living in a region with one of the 21 participating Dutch birth centres or in a region with the possibility for midwife-led hospital birth...
November 16, 2017: BMJ Open
https://www.readbyqxmd.com/read/29149182/comparison-between-public-and-private-sectors-of-care-and-disparities-in-adverse-neonatal-outcomes-following-emergency-intrapartum-cesarean-at-term-a-retrospective-cohort-study
#10
Woonji Jang, Christopher Flatley, Ristan M Greer, Sailesh Kumar
BACKGROUND: Perinatal outcomes may be influenced by a variety of factors including maternal demographics and medical condition as well as socio-economic status. The evidence for disparities in health outcomes stratified by type of care (public or private) is lacking. The aim of this study was to investigate short term neonatal outcomes following category 1 and 2 emergency cesareans at term between publicly and privately funded women at a single major tertiary centre in Australia. Category 1-immediate threat to life (maternal or fetal); Category 2-maternal or fetal compromise that is not immediately life-threatening...
2017: PloS One
https://www.readbyqxmd.com/read/29148890/changes-in-the-use-of-long-acting-reversible-contraceptive-methods-among-u-s-nulliparous-women-results-from-the-2006-2010-2011-2013-and-2013-2015-national-survey-of-family-growth
#11
Timothy O Ihongbe, Saba W Masho
OBJECTIVE: Nulliparous women in the United States have high rates of unintended pregnancy comparable with parous women. Long-acting reversible contraceptives (LARCs) are recommended as first-line contraceptive choices to reduce unintended pregnancy. However, use of LARCs among nulliparous women has been low. This study aims to examine changes in the prevalence of current LARC use among sexually experienced U.S. nulliparous women across the time period of 2006-2010, 2011-2013, and 2013-2015, and examine correlates of use...
November 17, 2017: Journal of Women's Health
https://www.readbyqxmd.com/read/29148634/labor-delivery-and-postpartum-complications-in-nulliparous-women-with-female-genital-mutilation-admitted-to-karamara-hospital
#12
Wondimu Gudu, Mutasim Abdulahi
Objectives: To assess labor, delivery and postpartum complications in nulliparous women with FGM/C and evaluate the attitude of mothers towards elimination of FGM. Methods: A prospective hospital based study using structured questionnaire was conducted between January to March 2015 at Karamara hospital, Jijiga, Ethiopia. All nulliparous women admitted for labor and delivery were included. Data were collected regarding circumcision status, events of labor, delivery; postpartum and neonatal outcomes as well as attitude of mothers towards elimination of FGM/C...
January 2017: Ethiopian Medical Journal
https://www.readbyqxmd.com/read/29146008/heat-and-pregnancy-related-emergencies-risk-of-placental-abruption-during-hot-weather
#13
Siyi He, Tom Kosatsky, Audrey Smargiassi, Marianne Bilodeau-Bertrand, Nathalie Auger
INTRODUCTION: Outdoor heat increases the risk of preterm birth and stillbirth, but the association with placental abruption has not been studied. Placental abruption is a medical emergency associated with major morbidity and mortality in pregnancy. We determined the relationship between ambient temperature and risk of placental abruption in warm seasons. MATERIAL AND METHODS: We performed a case-crossover analysis of 17,172 women whose pregnancies were complicated by placental abruption in Quebec, Canada from May to October 1989-2012...
November 13, 2017: Environment International
https://www.readbyqxmd.com/read/29141373/-a-concentration-response-observation-of-hydromorphone-combined-with-ropivacaine-in-labor-analgesia
#14
Y Y Lu, H Huang, W L Mao, R H Liu, M J Hu, L X Shao, M P Hu, J Li
Objective: To investigate the median effective dose (ED(50)) of hydromorphone and the appropriate concentration of ropivacaine combined with hydromorphone in epidural labor analgesia. Methods: One hundred and forty nulliparous women undergoing labor selected for delivery with epidural analgesia were enrolled in our hospital from January to June 2016. The first of top 50 women received 0.12% ropivacaine plus 20 μg/ml hydromorphone complex solution, then sequential women were used the modified sequential method to determine the ED(50) and ED(95) of hydromorphone...
November 14, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/29141178/peri-conception-and-first-trimester-diet-modifies-reproductive-development-in-bulls
#15
K J Copping, M D Ruiz-Diaz, C S Rutland, N P Mongan, M J Callaghan, I C McMillen, R J Rodgers, V E A Perry
Nutritional perturbation during gestation alters male reproductive development in rodents and sheep. In cattle both the developmental trajectory of the feto-placental unit and its response to dietary perturbations is dissimilar to that of these species. This study examined the effects of dietary protein perturbation during the peri-conception and first trimester periods upon reproductive development in bulls. Nulliparous heifers (n=360) were individually fed a high- or low-protein diet (HPeri and LPeri) from 60 days before conception...
November 16, 2017: Reproduction, Fertility, and Development
https://www.readbyqxmd.com/read/29140420/growth-trajectories-breast-size-and-breast-tissue-composition-in-a-british-pre-birth-cohort-of-young-women
#16
Rachel Denholm, Bianca De Stavola, John H Hipwell, Simon J Doran, Marta C Busana, Martin O Leach, David J Hawkes, Isabel Dos-Santos-Silva
Mammographic % density, the proportion of fibroglandular tissue in the breast, is a strong risk factor for breast cancer, but its determinants in young women are unknown. We examined associations between magnetic resonance imaging (MRI) breast-tissue composition at age 21 years and prospectively-collected measures of body size and composition from birth to early adulthood, and markers of puberty (all standardized), in a sample of 500 nulliparous women from a pre-birth cohort of children born in Avon, England, in 1991-1992 and followed up to 2011-2014...
November 13, 2017: American Journal of Epidemiology
https://www.readbyqxmd.com/read/29139277/tailor-management-to-the-patient-with-fibroids
#17
Marie O'Sullivan, Caroline Overton
Fibroids are benign, hormone-dependent tumours of uterine smooth muscle and connective tissue. They are commonly asymptomatic, but can cause symptoms such as heavy menstrual bleeding and pelvic pressure symptoms. Between 20 to 30% of women with heavy menstrual bleeding have fibroids. Fibroids are most prevalent in women aged 30-50 years and there may be a genetic predisposition. They are more common in black women than white women. Other risk factors include obesity and nulliparity. Asymptomatic women should only be referred if their uterus is palpable abdominally, if fibroids distort the uterine cavity or the uterus is larger than 12 cm in length...
March 2017: Practitioner
https://www.readbyqxmd.com/read/29138519/time-to-delivery-and-delivery-outcomes-comparing-three-methods-of-labor-induction-in-7551-nulliparous-women-a-population-based-cohort-study
#18
C Lindblad Wollmann, M Ahlberg, G Petersson, S Saltvedt, O Stephansson
OBJECTIVE: Determine time-to-delivery and mode-of-delivery in labor induction among women with unripe cervix. STUDY DESIGN: 7551 nulliparous women with singleton deliveries, ⩾37 weeks, Bishop Score ⩽6, induced with dinoprostone, misoprostol or transcervical single balloon catheter. Linear regression analysis was used to estimate mean time-to-delivery with β-estimates and 95% confidence intervals with adjustments. Multivariable logistic regression analysis was used to calculate odds of cesarean delivery, instrumental vaginal delivery, maternal and neonatal outcomes...
November 2017: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/29138035/defining-failed-induction-of-labor
#19
William A Grobman, Jennifer Bailit, Yinglei Lai, Uma M Reddy, Ronald J Wapner, Michael W Varner, John M Thorp, Kenneth J Leveno, Steve N Caritis, Mona Prasad, Alan T N Tita, George Saade, Yoram Sorokin, Dwight J Rouse, Sean C Blackwell, Jorge E Tolosa
BACKGROUND: While there are well-accepted standards for the diagnosis of arrested active-phase labor, the definition of a "failed" induction of labor remains less certain. One approach to diagnosing a failed induction is based on the duration of the latent phase. However, a standard for the minimum duration that the latent phase of a labor induction should continue, absent acute maternal or fetal indications for cesarean delivery, remains lacking. OBJECTIVE: The objective of this study was to determine the frequency of adverse maternal and perinatal outcomes as a function of the duration of the latent phase among nulliparous women undergoing labor induction...
November 11, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29136442/association-between-prepregnancy-body-mass-index-and-severe-maternal-morbidity
#20
Sarka Lisonkova, Giulia M Muraca, Jayson Potts, Jessica Liauw, Wee-Shian Chan, Amanda Skoll, Kenneth I Lim
Importance: Although high body mass index (BMI) is associated with adverse birth outcomes, the association with severe maternal morbidity is unclear. Objective: To examine the association between prepregnancy BMI and severe maternal morbidity. Design, Setting, and Participants: Retrospective population-based cohort study including all singleton hospital births in Washington State, 2004-2013. Demographic data and morbidity diagnoses were obtained from linked birth certificates and hospitalization files...
November 14, 2017: JAMA: the Journal of the American Medical Association
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