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Skin hyperpigmentation

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https://www.readbyqxmd.com/read/28429695/lichenoid-type-cutaneous-hyperpigmentation-induced-by-nebivolol
#1
Abdullah Nabi Aslan, Murat Can Güney, Murat Akçay, Telat Keleş, Engin Bozkurt
Cutaneous hyperpigmentation is a common and well-defined side effect of many drugs, such as non-steroidal anti-inflammatory drugs, beta-blockers, and tetracyclines, but to the best of our knowledge there is no case of skin discoloration related to nebivolol in the literature. Presently described is lichenoid type cutaneous hyperpigmentation in a 46-year-old female patient. Hyperpigmentation emerged 3 months after initiating use of nebivolol and resolved after cessation of drug use. It was concluded that effect emerged as result of therapeutic doses of nebivolol...
April 2017: Türk Kardiyoloji Derneği Arşivi: Türk Kardiyoloji Derneğinin Yayın Organıdır
https://www.readbyqxmd.com/read/28421656/oral-intake-of-boesenbergia-pandurata-extract-improves-skin-hydration-gloss-and-wrinkling-a-randomized-double-blind-and-placebo-controlled-study
#2
Do Un Kim, Hee Chul Chung, Changhee Kim, Jae-Kwan Hwang
BACKGROUND: Photoaging is a severe skin damage that occurs as a result of exposure to external elements, primarily ultraviolet (UV) irradiation. Chronically, UV-irradiated skin exhibits the signs of sunburn and hyperpigmentation with the destruction of connective tissues. Previously, Boesenbergia pandurata (B. pandurata) and its active compound panduratin A showed antiphotoaging activities in vitro and in vivo. OBJECTIVE: The aim of this study was to investigate the clinical efficacy of B...
April 18, 2017: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/28416402/improvement-of-skin-whitening-agents-efficiency-through-encapsulation-current-state-of-knowledge
#3
REVIEW
Elissa Ephrem, Hamid Elaissari, Hélène Greige-Gerges
Hyperpigmentation is one of the most common skin disorder that affects both men and women of all ethnic groups, caused by several factors, such as UV exposure and skin inflammation. Topical whitening agents were found to be the best and the least aggressive therapy for treating hyperpigmentation compared to instrumental approaches. However, topical treatment faces several obstacles due to the low stability of the whitening agents. Therefore, the encapsulation of these agents was found to be crucial as it enhances their physicochemical stability and increases their concentration at the targeted site via an improved skin permeation, penetration or distribution...
April 14, 2017: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/28413391/minocycline-induced-hyperpigmentation-in-a-patient-treated-with-erlotinib-for-non-small-cell-lung-adenocarcinoma
#4
Ann T Bell, John W Roman, Max L Gratrix, Christina E Brzezniak
INTRODUCTION: While epidermal growth factor receptor (EGFR) inhibitors have improved progression-free survival in patients with non-small cell lung cancer (NSCLC), one of the most common adverse effects is papulopustular skin eruption, which is frequently severe enough to be treated with oral minocycline or doxycycline. CASE: We present a case of an 87-year-old man who developed a severe papulopustular skin eruption secondary to erlotinib therapy for NSCLC. Control of the eruption with 100 mg of minocycline twice daily for 8 months eventually led to blue-gray skin hyperpigmentation...
January 2017: Case Reports in Oncology
https://www.readbyqxmd.com/read/28403910/topical-application-of-jaungo-in-atopic-dermatitis-patients-study-protocol-for-a-randomized-controlled-trial
#5
Younghee Yun, Youme Ko, Jin-Hyang Ahn, Bo-Hyoung Jang, Kyuseok Kim, Seong-Gyu Ko, Inhwa Choi
BACKGROUND: Atopic dermatitis (AD) is a common pruritic inflammatory skin disease with increasing prevalence. It can manifest with many different clinical phenotypes; however, in its chronic stage, hyperpigmentation, excoriation, lichenification, and dryness are the main symptoms. Jaungo comprises two herbs, Lithospermi radix and Angelica gigantis radix, and three carrier oils, and is an approved herbal ointment for xerosis cutis in Korea. In past studies, we demonstrated that Jaungo had anti-inflammatory and antiallergic activity in in vitro and in vivo AD models; however, there are few relevant randomized controlled clinical trials on Jaungo in AD...
April 12, 2017: Trials
https://www.readbyqxmd.com/read/28403263/microneedling-in-all-skin-types-a-review
#6
Lauren Meshkov Bonati, Gorana Kuka Epstein, Tamara Lazic Strugar
<p>INTRODUCTION: Microneedling procedures are growing in popularity for a wide variety of skin conditions. This paper comprehensively reviews the medical literature regarding skin needling efficacy and safety in all skin types and in multiple dermatologic conditions.</p> <p>METHODS: A PubMed literature search was conducted in all languages without restriction and bibliographies of relevant articles reviewed. Search terms included: "microneedling," "percutaneous collagen induction," "needling," "skin needling," and "dermaroller...
April 1, 2017: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/28403262/combination-of-in-office-chemical-peels-with-a-topical-comprehensive-pigmentation-control-product-in-skin-of-color-subjects-with-facial-hyperpigmentation
#7
Jeanine Downie, Katie Schneider, Lisa Goberdhan, Elizabeth T Makino, Rahul C Mehta
<p>Dyschromia is one of the primary complaints for patients with skin of color. Treatments need to achieve a balance between tolerability and efficacy to address existing hyperpigmentation without causing additional damage that could trigger post-inflammatory hyperpigmentation (PIH). An open-label, single-center study was conducted to assess the efficacy of a novel comprehensive pigmentation control serum (LYT2) combined with a series of three very superficial chemical peels (VP) in skin of color subjects...
April 1, 2017: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/28400639/association-of-dermatoses-with-duration-and-quantum-of-alcohol-intake-a-comparative-cross-sectional-study
#8
Yugal Kishor Sharma, Pankaj Shukla, Roopa Nayak, Preeti Kothari, Aayush Gupta
BACKGROUND: Chronic alcohol intake impacts skin directly, through organ dysfunction or by modifying preexisting dermatoses. However, dermatoses afflicting chronic alcoholics figure in a few studies only. AIM: This study aims to correlate the spectrum of dermatoses in chronic alcoholics with the quantum/duration of alcohol intake and raised liver transaminases. MATERIALS AND METHODS: Adult males, totaling 196, ascertained to fulfill the Royal College of Psychiatry criteria for chronic alcoholism by the de-addiction center and referred for dermatological consult were enrolled as cases, and similar number of age-/sex-matched teetotallers, as controls...
March 2017: Indian Journal of Dermatology
https://www.readbyqxmd.com/read/28384882/polymyxin-b-induced-diffuse-cutaneous-hyperpigmentation
#9
Sandeep Lahiry, Shouvik Choudhury, Ayan Mukherjee, Prajesh Kiran Bhunya, Moumita Bala
Polymyxin B is a polypeptide-antibiotic, primarily used for resistant Gram-negative infections, first obtained from bacterium Bacillus polymyxa in the late 1940s. Antibiotic spectrum are restricted to mainly gram negative bacterias like Enterobacter, E. coli, Klebsiella, Salmonella, Pasteurella, Bordetella, Shigella; and particularly organisms like Pseudomonas aeruginosa and Acinetobacter baumannii, which are extremely potent to acquire antibiotic resistance. Side effects include neurotoxicity and acute renal tubular necrosis...
February 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28384669/dermatologic-features-of-classic-movie-villains-the-face-of-evil
#10
Julie Amthor Croley, Vail Reese, Richard F Wagner
Importance: Dichotomous dermatologic depictions of heroes and villains in movies have been used since the silent film age. Objective: To evaluate the hero-villain skin dichotomy in film by (1) identifying dermatologic findings of the all-time top 10 American film villains, (2) comparing these dermatologic findings to the all-time top 10 American film heroes quantitatively and qualitatively, and (3) analyzing dermatologic portrayals of film villains in depth. Design, Setting, and Participants: In this cross-sectional study, dermatologic findings for film heroes and villains in mainstream media were identified and compared quantitatively using a χ2 test with α < ...
April 5, 2017: JAMA Dermatology
https://www.readbyqxmd.com/read/28367263/melasma-associated-with-topical-estrogen-cream
#11
Alyson Snyder, Rachel A Schiechert, Martin N Zaiac
A 47-year-old woman presented with hyperpigmented patches on her upper extremities. The patient had begun using a topical estrogen cream in the affected areas prior to noticing the hyperpigmentation. A diagnosis of melasma secondary to topical estrogen cream was made. While systemic hormones are a well-documented trigger for the development of melasma, this case represents the first report of melasma associated with topical estrogens. Topical estrogens are frequently prescribed to postmenopausal women for skin rejuvenation...
February 2017: Journal of Clinical and Aesthetic Dermatology
https://www.readbyqxmd.com/read/28355984/hydroxychloroquine-induced-hyperpigmentation-in-systemic-diseases-prevalence-clinical-features-and-risk-factors-a-cross-sectional-study-of-41-cases
#12
E Bahloul, M Jallouli, S Garbaa, S Marzouk, A Masmoudi, H Turki, Z Bahloul
Introduction Hydroxychloroquine is an antimalarial agent widely prescribed in internal medicine, rheumatology and dermatology. Its use can be complicated by various side effects including skin pigmentation. Objectives The aim of the study is to review epidemiological, clinical features and risk factors of hydroxychloroquine-induced pigmentation. Materials and methods We performed a cross-sectional study conducted over a period of 5 months. During this period, patients who had been treated with hydroxychloroquine for over 6 months, in the internal medicine department, underwent a complete dermatological examination...
January 1, 2017: Lupus
https://www.readbyqxmd.com/read/28349655/review-in-peeling-complications
#13
REVIEW
Izelda Maria Carvalho Costa, Patrick Silva Damasceno, Mariana Carvalho Costa, Keila Gabrielle Pati Gomes
Chemical peeling, a procedure wherein a chemical agent is applied to the skin to cause controlled destruction followed by regeneration and remodeling, is a dynamic tool for the treatment of acne, pigmentation issues, and photoaging [Journal of cutaneous and aesthetic surgery vol. 5 (2012) 254-260]. The results and complications are related to the depth of the procedure, with deeper peels producing more marked results and higher rates of complications. Complications are more likely with darker skin types, certain peeling agents, and sun exposure after treatment [Journal of cutaneous and aesthetic surgery vol...
March 27, 2017: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/28349520/a-retrospective-review-of-the-dermatologic-manifestations-of-chronic-arsenic-poisoning-in-the-philippines
#14
Sheena Maureen T Sy, Charissa M Salud-Gnilo, Claudine Yap-Silva, Erin Jane L Tababa
BACKGROUND: The Section of Dermatology of the University of the Philippines, Philippine General Hospital, reported a case of chronic arsenic poisoning from a community in Luzon island to the Department of Health resulting in the conduct of two health and environmental assessment missions in December 2014. OBJECTIVE: To describe the demographic profile and cutaneous manifestations of chronic arsenic poisoning among affected residents in Luzon, Philippines. METHODS: A review of the medical records of 116 residents screened during the health assessment missions in December 2014 was conducted...
March 28, 2017: International Journal of Dermatology
https://www.readbyqxmd.com/read/28349023/fractional-carbon-dioxide-laser-and-its-combination-with-subcision-in-improving-atrophic-acne-scars
#15
Mohammad Ali Nilforoushzadeh, Gita Faghihi, Fariba Jaffary, Elaheh Haftbaradaran, Sayed Mohsen Hoseini, Nafiseh Mazaheri
BACKGROUND: Acne is a very common skin disease in which scars are seen in 95% of the patients. Although numerous treatments have been recommended, researchers are still searching for a single modality to treat the complication due to its variety in shape and depth. We compared the effects of fractional carbon dioxide (CO2) laser alone and in combination with subcision in the treatment of atrophic acne scars. MATERIALS AND METHODS: This clinical trial study was performed in Skin Diseases and Leishmaniasis Research Center (Isfahan, Iran) during 2011-2012...
2017: Advanced Biomedical Research
https://www.readbyqxmd.com/read/28341693/minocycline-induced-skin-hyperpigmentation
#16
Jonathan Alpern, Anjum Kaka
No abstract text is available yet for this article.
March 24, 2017: Postgraduate Medical Journal
https://www.readbyqxmd.com/read/28328709/the-clinical-and-histological-effect-of-a-low-fluence-q-switched-1-064-nm-neodymium-yttrium-aluminum-garnet-laser-for-the-treatment-of-melasma-and-solar-lentigo-in-asians-prospective-randomized-and-split-face-comparative-study
#17
Chikako Kaminaka, Fukumi Furukawa, Yuki Yamamoto
BACKGROUND: The low-fluence Q-switched 1,064-nm neodymium:yttrium-aluminum-garnet laser (QSNYL) is popular for melasma treatment among Asians. OBJECTIVE: This study was to evaluate the clinical and histological effects of the low-fluence QSNYL for treatment of melasma and solar lentigo. MATERIALS AND METHODS: In this randomized split-face clinical study, 22 patients with melasma or solar lentigo received low-fluence QSNYL weekly for 10 sessions on one cheek...
March 21, 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/28300929/oculoectodermal-syndrome-twentieth-described-case-with-new-manifestations
#18
Daniela de Almeida Figueiras, Deborah Maria de Castro Barbosa Leal, Valter Kozmhinsky, Marina Coutinho Domingues Querino, Marina Genesia da Silva Regueira, Maria Gabriela de Morais Studart
Oculoectodermal syndrome is a rare disease characterized by the association of aplasia cutis congenita, epibulbar dermoids, and other abnormalities. This report describes the twentieth case of the disease. We report a 4-year-old female child who presented with the classical features of the syndrome: aplasia cutis congenita and epibulbar dermoids. Our case expands the clinical spectrum of the disease to include: diffuse hyperpigmentation (some following the Blaschko´s lines); hypopigmented skin areas on the trunk; arachnoid cyst on the right fronto-parietal border; rounded left side of the hippocampus; and dermoid cyst underlying the bulb-medullary transition...
September 2016: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/28300902/laptop-computer-induced-erythema-ab-igne-a-new-presentation-of-an-old-disease
#19
Ana Gabriela Salvio, Adauto Jose Nunes, Dora Patricia Ramirez Angarita
Erythema ab igne is a condition characterized by skin changes due to chronic exposure to moderate temperature. We describe a female patient with continuous use of a laptop computer on exposed legs for 6 months and consequent development of reticulated hyperpigmentation at the area. Histopathological examination revealed epidermal atrophy, collagen fragmentation, and vacuolar changes in the basal layer, among other signs. We consider this case to be a modern cause of erythema ab igne.
September 2016: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/28300437/botanicals-with-dermatologic-properties-derived-from-first-nations-healing
#20
Sophia Colantonio, Jason K Rivers
INTRODUCTION: Plants and algae have played a central role in the treatment of skin conditions in both traditional First Nations healing and in modern dermatology. The objective of this study was to examine the evidence supporting the dermatological use of seaweed, witch hazel, bearberry, and mayapple. METHODS: Four plants and algae used in traditional First Nations treatments of skin disease were selected based on expert recommendations. Several databases were searched to identify relevant citations without language restrictions...
December 1, 2016: Journal of Cutaneous Medicine and Surgery
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