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https://www.readbyqxmd.com/read/29908575/russian-traditional-medicine-in-dermatology
#1
Olga Y Olisova, Elena S Snarskaya, Victor V Gladko, Ekaterina P Burova
The use of herbal remedies for various medical issues is becoming increasingly commonplace in all fields of medicine, and dermatology is no exception. This review focuses on traditional dermatologic herbal remedies, commonly used in Russia, as the rich array of 11 different plant zones has resulted in a great variety of medicinal plants. Herbal remedies warrant deeper investigation and research, especially due to their active substance content, which may interfere with or reinforce the effect of modern medications, something that medical professionals should be aware of when prescribing treatments...
May 2018: Clinics in Dermatology
https://www.readbyqxmd.com/read/29893939/experience-of-perinatal-and-neonatal-chikungunya-virus-chikv-infection-in-a-tertiary-care-neonatal-centre-during-outbreak-in-north-india-in-2016-a-case-series
#2
Surender Kumar, Gopal Agrawal, Sanjay Wazir, Anil Kumar, Sandeep Dubey, Manish Balde, Bir Singh Yadav
Background: In 2016, there was a massive outbreak of chikungunya in North India. During the epidemic, we observed many neonatal and early infantile cases of chikungunya, with a probable perinatal transmission. Methods: This retrospective study was carried out in a tertiary care neonatal centre between August 2016 and November 2016. Chikungunya virus (CHIKV) infection was detected and confirmed by reverse transcription-polymerase chain reaction (RT-PCR) and/or serology (anti-CHIKV IgM) in mothers and infants...
June 9, 2018: Journal of Tropical Pediatrics
https://www.readbyqxmd.com/read/29891820/-2-e-5-e-2-5-bis-3-hydroxy-4-methoxybenzylidene-cyclopentanone-exerts-anti-melanogenesis-and-anti-wrinkle-activities-in-b16f10-melanoma-and-hs27-fibroblast-cells
#3
Hee Jin Jung, A Kyoung Lee, Yeo Jin Park, Sanggwon Lee, Dongwan Kang, Young Suk Jung, Hae Young Chung, Hyung Ryong Moon
Ultraviolet (UV) radiation exposure is the primary cause of extrinsic skin aging, which results in skin hyperpigmentation and wrinkling. In this study, we investigated the whitening effect of (2 E ,5 E )-2,5-bis(3-hydroxy-4-methoxybenzylidene)cyclopentanone (BHCP) on B16F10 melanoma and its anti-wrinkle activity on Hs27 fibroblasts cells. BHCP was found to potently inhibit tyrosinase, with 50% inhibition concentration (IC50 ) values of 1.10 µM and 8.18 µM for monophenolase (l-tyrosine) and diphenolase (l-DOPA), and the enzyme kinetics study revealed that BHCP is a competitive-type tyrosinase inhibitor...
June 11, 2018: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29877275/recombinant-thrombomodulin-used-to-successfully-treat-cronkhite-canada-syndrome-with-disseminated-intravascular-coagulation-due-to-sepsis-in-a-compromised-patient-a-case-report
#4
Kahori Morino, Yuichi Honma, Shinsuke Kumei, Tatsuyuki Watanabe, Keiichiro Kume, Ichiro Yoshikawa, Masaru Harada
Cronkhite-Canada syndrome (CCS) is a rare non-inherited disease characterized by gastrointestinal polyposis, chronic diarrhea, ectodermal dysplasia, skin hyperpigmentation, hair loss and nail atrophy. Although the efficacy of corticosteroid and immunomodulatory agents has been demonstrated, no standard therapy regimen has been established, and the prognosis of CCS is still poor due to various complications. We here in report a CCS patient complicated with severe sepsis and disseminated intravascular coagulation who was successfully treated by combined modality therapies, including recombinant human soluble thrombomodulin...
June 6, 2018: Internal Medicine
https://www.readbyqxmd.com/read/29870052/cinnamic-acid-derivatives-in-cosmetics-current-use-and-future-prospects
#5
REVIEW
Agnieszka Gunia-Krzyżak, Karolina Słoczyńska, Justyna Popiół, Paulina Koczurkiewicz, Henryk Marona, Elżbieta Pękala
Cinnamic acid derivatives are widely used in cosmetics and possess various functions. This group of compounds includes both naturally occurring as well as synthetic substances. On the basis of the Cosmetic Ingredient Database (CosIng) and available literature, this review summarizes their functions in cosmetics, including their physicochemical and biological properties as well as reported adverse effects. A perfuming function is typical of many derivatives of cinnamaldehyde, cinnamyl alcohol, dihydrocinnamyl alcohol, and cinnamic acid itself; these substances are commonly used in cosmetics all over the world...
June 5, 2018: International Journal of Cosmetic Science
https://www.readbyqxmd.com/read/29865165/downregulation-of-%C3%AE-melanocyte-stimulating-hormone-induced-activation-of-the-pax3-mitf-tyrosinase-axis-by-sorghum-ethanolic-extract-in-b16f10-melanoma-cells
#6
Da Hyun Lee, Sung Shin Ahn, Jung-Bong Kim, Yoongho Lim, Young Han Lee, Soon Young Shin
Ultraviolet irradiation-induced hyperpigmentation of the skin is associated with excessive melanin production in melanocytes. Tyrosinase (TYR) is a key enzyme catalyzing the rate-limiting step in melanogenesis. TYR expression is controlled by microphthalmia-associated transcription factor (MITF) expression. Sorghum is a cereal crop widely used in a variety of foods worldwide. Sorghum contains many bioactive compounds and is beneficial to human health. However, the effects of sorghum in anti-melanogenesis have not been well characterized...
June 1, 2018: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29846343/a-review-of-the-use-of-ultrasound-for-skin-tightening-body-contouring-and-cellulite-reduction-in-dermatology
#7
Margit Juhász, Dorota Korta, Natasha Atanaskova Mesinkovska
BACKGROUND: Ultrasound (US) technology uses acoustic waves to heat tissue, resulting in thermal damage and coagulative necrosis leading to the renewal of skin elasticity, body contouring, and destruction of cellulite. OBJECTIVE: This review will discuss the use of US for skin tightening, body contouring/sculpting, and cellulite reduction. MATERIALS AND METHODS: A literature search identified studies using US for skin tightening, body contouring/sculpting, and cellulite reduction...
May 24, 2018: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/29805353/cronkhite-canada-syndrome-associated-with-metastatic-colon-cancer
#8
Shirin Haghighi, Sima Noorali, Amir Houshang Mohammad Alizadeh
Cronkhite-Canada syndrome is characterized by gastrointestinal and ectodermal manifestations. In this paper, we describe a 64-year-old Iranian male, presenting with Cronkhite-Canada syndrome with metastatic colon cancer. The patient was suffering from hair loss, which occurred on the scalp at first and then, during 5 months, extended to the whole body. After that, his sense of taste was impaired, and 2 months later, gastrointestinal symptoms gradually started, with weight loss of 20 kg over 2 months with an initial weight of 100 kg...
January 2018: Case Reports in Gastroenterology
https://www.readbyqxmd.com/read/29803170/sargaquinoic-acid-ameliorates-hyperpigmentation-through-camp-and-erk-mediated-downregulation-of-mitf-in-%C3%AE-msh-stimulated-b16f10-cells
#9
Mohammed Shariful Azam, Misung Kwon, Jinkyung Choi, Hyeung-Rak Kim
Hyperpigmentation disorders of the skin adversely influence the quality of life. We previously demonstrated the hypopigmenting properties of the ethanolic extract from Sargassum serratifolium and identified sargaquinoic acid (SQA) as an active component. The current study aims to investigate the hypopigmenting action of SQA in α-melanocyte stimulating hormone (α-MSH)-stimulated B16F10 cells. SQA attenuated cellular melanin synthesis by inhibiting the expression of the melanogenic enzymes, including tyrosinase (TYR), tyrosinase-related protein 1 (TRP1), and TRP2...
May 22, 2018: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/29799583/treatment-of-burn-scars-in-fitzpatrick-phototype-iii-patients-with-a-combination-of-pulsed-dye-laser-and-non-ablative-fractional-resurfacing-1550-nm-erbium-glass-1927-nm-thulium-laser-devices
#10
Joy Tao, Amanda Champlain, Charles Weddington, Lauren Moy, Rebecca Tung
Introduction: Burn scars cause cosmetic disfigurement and psychosocial distress. We present two Fitzpatrick phototype (FP) III patients with burn scars successfully treated with combination pulsed dye laser (PDL) and non-ablative fractional lasers (NAFL). Case 1: A 30-year-old, FP III woman with a history of a second-degree burn injury to the bilateral arms and legs affecting 30% body surface area (BSA) presented for cosmetic treatment. The patient received three treatments with 595 nm PDL (7 mm, 8 J, 6 ms), six with the 1550 nm erbium:glass laser (30 mJ, 14% density, 4-8 passes) and five with the 1927 nm thulium laser (10 mJ, 30% density, 4-8 passes)...
January 2018: Scars, burns & healing
https://www.readbyqxmd.com/read/29794637/-treatment-of-facial-hypopigmented-scars-by-the-laser-hole-technique-using-a-non-fractional-carbon-dioxide-laser-in-asian
#11
Jin Sik Burm, Yung Ki Lee, Cho Jae Young
BACKGROUND: Facial hypopigmented scars are usually characterized by white color and glossy surface. To correct the two problems simultaneously, we tried to induce persistent post-inflammatory hyperpigmentation for color and to build multiple pitted scars like facial skin pores for texture. This study describes a laser hole method using a traditional non-fractional carbon dioxide (CO2) laser for treatment of facial hypopigmented scars and evaluates the clinical results. METHODS: Forty three facial hypopigmented scars in 27 patients were treated, excluding protruding or thick scars...
May 14, 2018: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/29790609/detection-of-hydroquinone-by-raman-spectroscopy-in-patients-with-melasma-before-and-after-treatment
#12
R Cabrera-Alonso, E Guevara, M G Ramírez-Elías, B Moncada, F J González
BACKGROUND: Melasma is an acquired, facial hyperpigmentation without a specific origin. It is regularly associated with multiple etiologic factors such as pregnancy, genetic, racial, and from estrogen administration. Among the methods to treat skin hyperpigmentation a series of skin bleaching agents have been used. At present, the most commonly used agent is known as hydroquinone. Nowadays, it is known that hydroquinone can cause cancer in animals with unknown relevance to humans. MATERIAL AND METHODS: In this work, Raman spectroscopy was used to observe the presence of hydroquinone in the skin of 18 patients who have been under treatment for melasma...
May 23, 2018: Skin Research and Technology
https://www.readbyqxmd.com/read/29786154/topical-polyhydroxy-acid-treatment-for-autosomal-recessive-congenital-ichthyosis-in-the-golden-retriever-a-prospective-pilot-study
#13
Anna Puigdemont, Nicla Furiani, Michela De Lucia, Isaac Carrasco, Laura Ordeix, Dolors Fondevila, Laura Ramió-Lluch, Pilar Brazis
BACKGROUND: Autosomal recessive congenital ichthyosis (ARCI) in golden retrievers is due to a PNPLA1 gene mutation, which plays a role in epidermal lipid organization and metabolism. Topical therapies are used to reduce scaling; however, there are few published efficacy studies. OBJECTIVES: To examine the efficacy of topical treatment based on gluconolactone, a polyhydroxy acid with known beneficial effects on stratum corneum structure. ANIMALS: Sixteen golden retriever dogs with clinical signs of ARCI and PCR-confirmed PNPLA1 gene mutation...
May 22, 2018: Veterinary Dermatology
https://www.readbyqxmd.com/read/29785318/role-of-nanotechnology-in-cosmeceuticals-a-review-of-recent-advances
#14
REVIEW
Shreya Kaul, Neha Gulati, Deepali Verma, Siddhartha Mukherjee, Upendra Nagaich
Nanotechnology manifests the progression in the arena of research and development, by increasing the efficacy of the product through delivery of innovative solutions. To overcome certain drawbacks associated with the traditional products, application of nanotechnology is escalating in the area of cosmeceuticals. Cosmeceuticals are regarded as the fastest growing segment of the personal care industry and the use has risen drastically over the years. Nanocosmeceuticals used for skin, hair, nail, and lip care, for conditions like wrinkles, photoaging, hyperpigmentation, dandruff, and hair damage, have come into widespread use...
2018: Journal of Pharmaceutics
https://www.readbyqxmd.com/read/29782303/clindamycin-induced-maculopapular-exanthema-with-preferential-involvement-of-striae-distensae-a-koebner-phenomenon
#15
Benigno Monteagudo, Miguel Cabanillas, Pilar Iriarte, Aquilina Ramírez-Santos, Elvira León-Muinos, Daniel González-Vilas, Óscar Suárez-Amor
Clindamycin is a lincomycin-derived antibiotic useful for the treatment of anaerobic and Gram-positive aerobic bacterial infections. Cutaneous adverse reactions are usually maculopapular exanthemas, although hypersensitivity syndrome, acute generalized exanthematous pustulosis, and Stevens-Johnson syndrome have also been reported (1). We report the case of a patient with a maculopapular rash triggered by clindamycin who developed cutaneous lesions on striae distensae (SD). A 47-year-old woman was referred to our clinic for pruritic cutaneous lesions which had started 6 days earlier...
April 2018: Acta Dermatovenerologica Croatica: ADC
https://www.readbyqxmd.com/read/29782300/poikilodermatous-mycosis-fungoides-rare-entity-different-treatment-modalities
#16
Sandra Jerković Gulin, Romana Čeović, Ivana Ilić, Mirna Bradamante, Zrinka Bukvić Mokos, Krešimir Kostović
Poikilodermatous mycosis fungoides (PMF) is a rare clinical variant of early-stage MF with peculiar histological features. Poikiloderma occurs in many different clinical conditions, which makes a diagnostic procedure more complicated. PMF belongs to a group of MF variants with low risk of disease progression. We report a case of a 64-year-old woman, who presented with mottled skin aspect of erythema, poikilodermatous patches (hypopigmentation, hyperpigmentation, atrophy, and telangiectasia) on more than 80% of the body...
April 2018: Acta Dermatovenerologica Croatica: ADC
https://www.readbyqxmd.com/read/29774634/study-of-hyperpigmentation-in-human-skin-disorder-using-different-electron-microscopy-techniques
#17
Seulgi Noh, Hyosun Choi, Ji Soo Kim, Il-Hwan Kim, Ji Young Mun
There is a global trend of increase in the demand for three-dimensional electron microscopy with high resolution. The ultrastructural change and related functional studies are necessary to investigate biological phenomena. In this study, currently available 3D reconstruction techniques of electron microscopes (serial block-face scanning electron microscopy and focused ion beam-scanning electron microscopy) were used to investigate hyperpigmentary disorders in human skin. In the basal layer of the epidermis in the human skin, there are melanocytes that produce melanin and keratinocytes that act as a barrier against environmental damage...
May 18, 2018: Microscopy Research and Technique
https://www.readbyqxmd.com/read/29772369/sciatic-neuralgia-caused-by-may-thurner-syndrome-case-report
#18
Kazuaki Yamamoto, Gakuji Gondo, Hidemitsu Ogino, Tsuyoshi Watanabe, Masahiko Tanaka, Satoshi Tanaka, Taisuke Kawasaki
BACKGROUND: Sciatic neuralgia (SN) is a type of pain commonly associated with lumbosacral radiculopathy. May-Thurner syndrome (MTS) is a disease characterized by venous congestion in the left common iliac vein (LCIV) due to right common iliac artery compression. In this report, the authors describe a case of MTS with SN as the first presenting symptom. CASE DESCRIPTION: A 53-year-old man gradually developed left SN; however, radiological examination showed no causal findings...
May 14, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29748107/green-bone-minocycline-induced-discoloration-of-bone-rarely-reported-in-foot-and-ankle
#19
Molly S Judge, J Michael Miller, Michael Lyons
The tetracycline antibiotics incorporate into bone similar to bisphosphonates. Tetracycline stains bone a fluorescent yellow and minocycline, more commonly used for chronic acne, stains bone dark green. Owing to its frequent use, the occurrence of green bone discoloration due to antibiotics in the tetracycline class is well understood. Its pigmentation can be seen through delicate, thin tissue as a dark blue-gray. Histologic inspection of this bone will confirm a benign condition without evidence of bone disease...
May 7, 2018: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/29739761/long-lasting-remission-in-a-case-of-cronkhite-canada-syndrome
#20
Maria Pina Dore, Rosanna Satta, Alberto Murino, Giovanni Mario Pes
Cronkhite-Canada syndrome is a rare disease characterised by diffuse gastrointestinal polyposis, diarrhoea, weight loss, skin hyperpigmentation, onychodystrophy and alopecia. More than 500 cases have been described in the medical literature so far. The disease is probably caused by immune-mediated inflammatory mechanisms, and the diagnosis is based on clinical history, physical examination, endoscopic findings and histology. Differentiating this condition from other clinical entities presenting with similar signs and symptoms may be challenging...
May 8, 2018: BMJ Case Reports
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