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https://www.readbyqxmd.com/read/28345756/the-dawn-of-dentistry-in-the-late-upper-paleolithic-an-early-case-of-pathological-intervention-at-riparo-fredian
#1
Gregorio Oxilia, Flavia Fiorillo, Francesco Boschin, Elisabetta Boaretto, Salvatore A Apicella, Chiara Matteucci, Daniele Panetta, Rossella Pistocchi, Franca Guerrini, Cristiana Margherita, Massimo Andretta, Rita Sorrentino, Giovanni Boschian, Simona Arrighi, Irene Dori, Giuseppe Mancuso, Jacopo Crezzini, Alessandro Riga, Maria C Serrangeli, Antonino Vazzana, Piero A Salvadori, Mariangela Vandini, Carlo Tozzi, Adriana Moroni, Robin N M Feeney, John C Willman, Jacopo Moggi-Cecchi, Stefano Benazzi
OBJECTIVES: Early evidence for the treatment of dental pathology is found primarily among food-producing societies associated with high levels of oral pathology. However, some Late Pleistocene hunter-gatherers show extensive oral pathology, suggesting that experimentation with therapeutic dental interventions may have greater antiquity. Here, we report the second earliest probable evidence for dentistry in a Late Upper Paleolithic hunter-gatherer recovered from Riparo Fredian (Tuscany, Italy)...
March 27, 2017: American Journal of Physical Anthropology
https://www.readbyqxmd.com/read/28343040/the-influence-of-lead-content-in-drinking-water-household-dust-soil-and-paint-on-blood-lead-levels-of-children-in-flin-flon-manitoba-and-creighton-saskatchewan
#2
Adam M Safruk, Erin McGregor, Melissa L Whitfield Aslund, Paul H Cheung, Celine Pinsent, Blair J Jackson, Alan T Hair, Murray Lee, Elliot A Sigal
Lead exposure continues to be an important health issue despite the general removal of lead sources in commercial and industrial applications. Low levels of lead exposure have been found to produce adverse neurodevelopmental effects in children with no evidence that a threshold exists for this critical endpoint. Blood lead levels (BLLs) were measured in children (n=118) under the age of 7years in the northern Canadian smelter community of Flin Flon, Manitoba and Creighton, Saskatchewan. An environmental sampling component was included to examine the relationship between lead content in outdoor soil, household dust, tap water, and paint within a given household and the corresponding BLLs in participating children...
March 23, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28332480/honey-bee-hairs-and-pollenkitt-are-essential-for-pollen-capture-and-removal
#3
Guillermo J Amador, Marguerite Matherne, D'Andre Waller, Megha Mathews, Stanislav N Gorb, David L Hu
While insect grooming has been observed and documented for over one hundred years, we present the first quantitative analysis of this highly dynamic process. Pollinating insects, like honey bees, purposely cover themselves with millions of pollen particles that, if left ungroomed, would make sensing and controlled flight difficult. How do they get clean? We show that the hairs on insect eyes are tuned to the pollen they collect; namely, the hairs are spaced so that they suspend pollen above the body for easy removal by the forelegs...
March 23, 2017: Bioinspiration & Biomimetics
https://www.readbyqxmd.com/read/28329619/bitemporal-hair-loss-related-to-traction-alopecia
#4
Oscar Muñoz Moreno-Arrones, Sergio Vañó-Galván
We present a 24-year-old woman that had received a diagnosis of alopecia areata in the past and was treated with topical 19 corticosteroids with little improvement. Instead, the patient exhibited bitemporal alopecia of one year of evolution related to 20 traction alopecia. Traction alopecia is characterized by localized hair loss related to persistent excessive traction. Although it is 21 initially a reversible condition, if this excessive traction is not removed permanent alopecia may develop.
September 15, 2016: Dermatology Online Journal
https://www.readbyqxmd.com/read/28329583/dermatologic-care-of-the-transgender-patient
#5
Timothy Hermosura Almazan, Filamer D Kabigting
Literature is limited regarding the medical and cosmetic dermatologic issues pertinent to transgender patients and the reasons why 19 transgender individuals seek care from dermatologists. Clinical management of this population has historically been limited to 20 mental health providers, endocrinologists, and select surgeons with expertise in sex reassignment surgery. The impact of hormonal 21 therapy on transgender skin has been well documented in endocrinology journals, but is underrepresented in dermatology 22 literature...
October 15, 2016: Dermatology Online Journal
https://www.readbyqxmd.com/read/28328662/surgical-management-of-hidradenitis-suppurativa-a-14-year-retrospective-review-of-98-consecutive-patients
#6
Kathleen S Romanowski, Alice Fagin, Bridget Werling, Gretchen Kass, Junlin Liao, Thomas Granchi, Gerald P Kealey, Lucy Wibbenmeyer
Hidradenitis suppurativa (HS) is a debilitating suppurative disease of the apocrine/follicular glands. Medical treatment has some efficacy in early-stage disease but is costly and requires frequent physician visits. Advanced disease usually requires surgical intervention. This treatment has not been well described in the literature. We sought to review our experience with HS treatment in a large surgical cohort. A retrospective review of 98 consecutive HS patients from 2000 to 2014 was performed. A two-stage operative approach was used...
March 15, 2017: Journal of Burn Care & Research: Official Publication of the American Burn Association
https://www.readbyqxmd.com/read/28323652/intraoral-laser-hair-removal-of-a-palate-free-flap-tips-and-technique
#7
Bernice Y Yan, Brian P Hibler, Karen L Connolly, Anthony M Rossi
No abstract text is available yet for this article.
March 17, 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/28293016/umbilical-pilonidal-sinus-an-underestimated-and-little-known-clinical-entity-report-of-two-cases
#8
Mehmet Kaplan, Elif Tugce Kaplan, Tugba Kaplan, Fatma Cigdem Kaplan
BACKGROUND Umbilical pilonidal sinus (UPS) is a rare disease of young, hirsute, dark men with deep navels and poor personal hygiene. UPS could easily be misdiagnosed and mistreated due to its rarity and lack of awareness of the condition by physicians. However, the diagnosis is easy to establish with physical examination and a detailed history. Although it is being diagnosed and reported more frequently, there is still no consensus regarding best treatment options. CASE REPORT In this report, we present two cases of UPS, one in a man and one in a woman, who had typical symptoms of pain, swelling, and intermittent malodorous discharge from the umbilicus...
March 15, 2017: American Journal of Case Reports
https://www.readbyqxmd.com/read/28270164/tropomyosin-receptor-antagonism-in-cylindromatosis-trac-an-early-phase-trial-of-a-topical-tropomyosin-kinase-inhibitor-as-a-treatment-for-inherited-cyld-defective-skin-tumours-study-protocol-for-a-randomised-controlled-trial
#9
Amy Cranston, Deborah D Stocken, Elaine Stamp, David Roblin, Julia Hamlin, James Langtry, Ruth Plummer, Alan Ashworth, John Burn, Neil Rajan
BACKGROUND: Patients with germline mutations in a tumour suppressor gene called CYLD develop multiple, disfiguring, hair follicle tumours on the head and neck. The prognosis is poor, with up to one in four mutation carriers requiring complete surgical removal of the scalp. There are no effective medical alternatives to treat this condition. Whole genome molecular profiling experiments led to the discovery of an attractive molecular target in these skin tumour cells, named tropomyosin receptor kinase (TRK), upon which these cells demonstrate an oncogenic dependency in preclinical studies...
March 7, 2017: Trials
https://www.readbyqxmd.com/read/28263778/evaluation-of-the-bundle-zero-surgical-site-infection-to-prevent-surgical-site-infection-in-vascular-surgery
#10
María Fernández-Prada, Carmen Martínez-Ortega, Livia Revuelta-Mariño, Ángeles Menéndez-Herrero, Juan F Navarro-Gracia
OBJECTIVE: To compare the incidence of Surgical Site Infections (SSIs) before and after the implementation of a bundle of care called 'Zero Surgical Site Infection'. Secondary goals included estimating measures of association and their potential impact, determining care management indicators in vascular surgery, and evaluating the level of compliance with the bundle. METHODS: This is a prospective observational study with a historic control group. The bundle included: 1) removal of body hair with clippers; 2) preoperative showering with chlorhexidine soap; 3) preparation of the surgical field with alcoholic chlorhexidine 2%; 4) adequacy of antimicrobial prophylaxis; 5) and 6) intra- and post-operative glycemic and central temperature control...
March 2, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28263708/supporting-cells-remove-and-replace-sensory-receptor-hair-cells-in-a-balance-organ-of-adult-mice
#11
Stephanie A Bucks, Brandon C Cox, Brittany A Vlosich, James P Manning, Tot B Nguyen, Jennifer S Stone
Vestibular hair cells in the inner ear encode head movements and mediate the sense of balance. These cells undergo cell death and replacement (turnover) throughout life in non-mammalian vertebrates. However, there is no definitive evidence that this process occurs in mammals. We used fate-mapping and other methods to demonstrate that utricular type II vestibular hair cells undergo turnover in adult mice under normal conditions. We found that supporting cells phagocytose both type I and II hair cells. Plp1-CreER(T2)-expressing supporting cells replace type II hair cells...
March 6, 2017: ELife
https://www.readbyqxmd.com/read/28261924/the-effect-of-a-herbal-paste-and-oil-extract-on-the-lipid-content-of-canine-hair-fibres
#12
Yutaka Momota, Kenichiro Shimada, Chihiro Kadoya, Azusa Gin, Jun Kobayashi, Yuka Nakamura, Takako Matsubara, Toshinori Sako
BACKGROUND: Application of herbal paste and oil to a dog's coat and body before rinsing (often combining with shampooing) is a cosmetic therapy available in Japan. It is highly appreciated by users, who claim that the treatment makes the coat shinier, improves volume and eliminates tangles. However, there has been no scientific evaluation of such treatments. HYPOTHESIS/OBJECTIVES: Improvement of hair condition is derived from oils such as sebum and conditioning oils because chemicals are not used...
March 6, 2017: Veterinary Dermatology
https://www.readbyqxmd.com/read/28259786/new-methodology-for-mechanical-characterization-of-human-superficial-facial-tissue-anisotropic-behaviour-in-vivo
#13
C Then, B Stassen, K Depta, G Silber
Mechanical characterization of human superficial facial tissue has important applications in biomedical science, computer assisted forensics, graphics, and consumer goods development. Specifically, the latter may include facial hair removal devices. Predictive accuracy of numerical models and their ability to elucidate biomechanically relevant questions depends on the acquisition of experimental data and mechanical tissue behavior representation. Anisotropic viscoelastic behavioral characterization of human facial tissue, deformed in vivo with finite strain, however, is sparse...
February 21, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28259688/hair-growth-cycle-is-arrested-in-scd1-deficiency-by-impaired-wnt3a-palmitoleoylation-and-retrieved-by-artificial-lipid-barrier
#14
Wilhelm Stoffel, Inga Schmidt-Soltau, Britta Jenke, Erika Binczek, Ina Hammels
Stearoyl-CoA desaturase 1 (SCD1) is the dominant member of the SCD-isozyme family, regarded as a major regulator of lipid and energy metabolism in liver and adipose tissue. SCD1-deficiency impairs the desaturation of de novo-synthesized palmitoyl- and stearoyl-CoA to palmitoleoyl- and oleoyl- CoA. Scd1-/- mice develop metabolic waste syndrome and skin lesions: epidermal barrier disruption, alopecia and degeneration of sebaceous glands. The unifying molecular link between the two divergent traits remains incompletely understood...
March 1, 2017: Journal of Investigative Dermatology
https://www.readbyqxmd.com/read/28250994/evaluation-of-the-hair-cell-regeneration-in-zebrafish-larvae-by-measuring-and-quantifying-the-startle-responses
#15
Changquan Wang, Zhenmin Zhong, Peng Sun, Hanbing Zhong, Hongzhe Li, Fangyi Chen
The zebrafish has become an established model organism for the study of hearing and balance systems in the past two decades. The classical approach to examine hair cells is to use dye to conduct selective staining, which shows the number and morphology of hair cells but does not reveal their function. Startle response is a behavior closely related to the auditory function of hair cells; therefore it can be used to measure the function of hair cells. In this study, we developed a device to measure the startle response of zebrafish larvae...
2017: Neural Plasticity
https://www.readbyqxmd.com/read/28218404/topical-medication-instillation-techniques-for-glaucoma
#16
REVIEW
Li Xu, Xuemei Wang, Meijing Wu
BACKGROUND: Glaucoma is a leading cause of irreversible blindness worldwide and the second most common cause of blindness after cataracts. The primary treatment for glaucoma aims to lower intraocular pressure (IOP) with the use of topical medicines. Topical medication instillation techniques, such as eyelid closure and nasolacrimal occlusion when instilling drops, have been proposed as potential methods to increase ocular absorption and decrease systemic absorption of the drops. OBJECTIVES: To investigate the effectiveness of topical medication instillation techniques compared with usual care or another method of instillation of topical medication in the management of glaucoma or ocular hypertension...
February 20, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28216123/ablation-of-the-auditory-cortex-results-in-changes-in-the-expression-of-neurotransmission-related-mrnas-in-the-cochlea
#17
Verónica Lamas, José M Juiz, Miguel A Merchán
The auditory cortex (AC) dynamically regulates responses of the Organ of Corti to sound through descending connections to both the medial (MOC) and lateral (LOC) olivocochlear efferent systems. We have recently provided evidence that AC has a reinforcement role in the responses to sound of the auditory brainstem nuclei. In a molecular level, we have shown that descending inputs from AC are needed to regulate the expression of molecules involved in outer hair cell (OHC) electromotility control, such as prestin and the α10 nicotinic acetylcholine receptor (nAchR)...
March 2017: Hearing Research
https://www.readbyqxmd.com/read/28210387/efficacy-of-a-low-fluence-high-repetition-rate-810nm-diode-laser-for-permanent-hair-reduction-in-indian-patients-with-skin-types-iv-vi
#18
Madhuri Agarwal, Sangeeta Velaskar, Michael H Gold
Background: The study's aim is to evaluate the novel "in motion" technique for permanent hair removal using a low level fluence/high repetition rate on patients with a dark skin type over different areas of the body. Objectives: To assess fluence, accumulative energy, and number of treatments needed to achieve a significant hair reduction and patient satisfaction with minimal side effects, low discomfort levels, and high safety profile in a skin type IV-VI Indian patients. Methods: Seventy-one Indian female patients with skin type IV-VI were enrolled in the study...
November 2016: Journal of Clinical and Aesthetic Dermatology
https://www.readbyqxmd.com/read/28203534/comparison-of-methanol-and-isopropanol-as-wash-solvents-for-determination-of-hair-cortisol-concentration-in-grizzly-bears-and-polar-bears
#19
Thomas Kroshko, Luciene Kapronczai, Marc R L Cattet, Bryan J Macbeth, Gordon B Stenhouse, Martyn E Obbard, David M Janz
Methodological differences among laboratories are recognized as significant sources of variation in quantification of hair cortisol concentration (HCC). An important step in processing hair, particularly when collected from wildlife, is the choice of solvent used to remove or "wash" external hair shaft cortisol prior to quantification of HCC. The present study systematically compared methanol and isopropanol as wash solvents for their efficiency at removing external cortisol without extracting internal hair shaft cortisol in samples collected from free-ranging grizzly bears and polar bears...
2017: MethodsX
https://www.readbyqxmd.com/read/28190985/a-comparison-between-the-tie-over-and-closed-suction-drainage-therapeutic-strategies-in-patients-suffering-from-sacral-pilonidal-sinus
#20
Mojtaba Ahmadinejad, Koorosh Ahmadi, Izadmehr Ahmadinejad, Amir Masoud Hashemian, Peyman Khademhoseini
BACKGROUND AND OBJECTIVES: Pilonidal sinus is a disease in the sacrococcygeal region diagnosed through the purulent discharges of the above-said region. Although the exact pathology and etiology of those suffering from pilonidal is not clear yet, the presence of hair seemingly plays a major role in the process of infection and the granulation tissue. Several techniques have been identified for pilonidal surgery. These techniques primarily fall within two categories: Primary repair and Lay open...
December 2016: International Journal of Biomedical Science: IJBS
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