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https://www.readbyqxmd.com/read/28210387/efficacy-of-a-low-fluence-high-repetition-rate-810nm-diode-laser-for-permanent-hair-reduction-in-indian-patients-with-skin-types-iv-vi
#1
Madhuri Agarwal, Sangeeta Velaskar, Michael H Gold
Background: The study's aim is to evaluate the novel "in motion" technique for permanent hair removal using a low level fluence/high repetition rate on patients with a dark skin type over different areas of the body. Objectives: To assess fluence, accumulative energy, and number of treatments needed to achieve a significant hair reduction and patient satisfaction with minimal side effects, low discomfort levels, and high safety profile in a skin type IV-VI Indian patients. Methods: Seventy-one Indian female patients with skin type IV-VI were enrolled in the study...
November 2016: Journal of Clinical and Aesthetic Dermatology
https://www.readbyqxmd.com/read/28203534/comparison-of-methanol-and-isopropanol-as-wash-solvents-for-determination-of-hair-cortisol-concentration-in-grizzly-bears-and-polar-bears
#2
Thomas Kroshko, Luciene Kapronczai, Marc R L Cattet, Bryan J Macbeth, Gordon B Stenhouse, Martyn E Obbard, David M Janz
Methodological differences among laboratories are recognized as significant sources of variation in quantification of hair cortisol concentration (HCC). An important step in processing hair, particularly when collected from wildlife, is the choice of solvent used to remove or "wash" external hair shaft cortisol prior to quantification of HCC. The present study systematically compared methanol and isopropanol as wash solvents for their efficiency at removing external cortisol without extracting internal hair shaft cortisol in samples collected from free-ranging grizzly bears and polar bears...
2017: MethodsX
https://www.readbyqxmd.com/read/28190985/a-comparison-between-the-tie-over-and-closed-suction-drainage-therapeutic-strategies-in-patients-suffering-from-sacral-pilonidal-sinus
#3
Mojtaba Ahmadinejad, Koorosh Ahmadi, Izadmehr Ahmadinejad, Amir Masoud Hashemian, Peyman Khademhoseini
BACKGROUND AND OBJECTIVES: Pilonidal sinus is a disease in the sacrococcygeal region diagnosed through the purulent discharges of the above-said region. Although the exact pathology and etiology of those suffering from pilonidal is not clear yet, the presence of hair seemingly plays a major role in the process of infection and the granulation tissue. Several techniques have been identified for pilonidal surgery. These techniques primarily fall within two categories: Primary repair and Lay open...
December 2016: International Journal of Biomedical Science: IJBS
https://www.readbyqxmd.com/read/28190856/virilism-and-ectopic-expression-of-hsd17b5-in-mature-cystic-teratoma
#4
Yohei Kawaguchi, Hiroko Mizuno, Mai Horikawa, Mayuko Kano, Kengo Yamada, Fumiko Yamakawa, Takashi Maekawa, Yuto Yamazaki, Keely M McNamara, Hironobu Sasano, Masayuki Hayashi
Mature cystic teratoma (MCT) is rarely involved in the overproduction of steroid hormones in contrast to sex cord stromal tumors. A 31-year-old woman visited our hospital with hirsutism, hoarseness, and hair loss from the scalp. Serum testosterone and free-testosterone levels were 7.3 ng/ml and 2.3 pg/ml, respectively, which were markedly in excess of the age adjusted female standard levels. Basal blood levels of steroid hormones and serum levels of 17-hydroxyprogesterone at 1 h after intravenous injection of adrenocorticotropic hormone demonstrated that 21-hydroxylase deficiency was not the underlying cause of her virilization...
2017: Tohoku Journal of Experimental Medicine
https://www.readbyqxmd.com/read/28164458/comparison-of-hair-removal-efficacy-and-side-effect-of-neodymium-yttrium-aluminum-garnet-laser-and-intense-pulsed-light-systems-18-month-follow-up
#5
Georgina Zita Szima, Eszter Anna Janka, Anikó Kovács, Blanka Bortély, Edina Bodnár, Irina Sawhney, Éva Szabó, Éva Remenyik
BACKGROUND: Photothermal destruction of hair shaft melanin with intense pulsed light (IPL) and neodymium:yttrium-aluminum-garnet (Nd:YAG) laser has become an effective treatment of hair removal. AIMS: Our aim was to compare efficacy, satisfactory levels, safety, and side effects of Nd:YAG and IPL in hair reduction. METHODS: This was a prospective randomized intrapatient, right-left, assessor-blinded comparison of Nd:YAG vs IPL. There were 38 volunteers recruited...
February 6, 2017: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/28157540/large-intragenic-deletion-in-dstyk-underlies-autosomal-recessive-complicated-spastic-paraparesis-spg23
#6
John Y W Lee, Chao-Kai Hsu, Magdalene Michael, Arti Nanda, Lu Liu, James R McMillan, Celine Pourreyron, Takuya Takeichi, Jakub Tolar, Evan Reid, Thomas Hayday, Sergiu C Blumen, Saif Abu-Mouch, Rachel Straussberg, Lina Basel-Vanagaite, Yael Barhum, Yasmin Zouabi, Hejab Al-Ajmi, Hsin-Yu Huang, Ting-Chien Lin, Masashi Akiyama, Julia Y Y Lee, W H Irwin McLean, Michael A Simpson, Maddy Parsons, John A McGrath
SPG23 is an autosomal-recessive neurodegenerative subtype of lower limb spastic paraparesis with additional diffuse skin and hair dyspigmentation at birth followed by further patchy pigment loss during childhood. Previously, genome-wide linkage in an Arab-Israeli pedigree mapped the gene to an approximately 25 cM locus on chromosome 1q24-q32. By using whole-exome sequencing in a further Palestinian-Jordanian SPG23 pedigree, we identified a complex homozygous 4-kb deletion/20-bp insertion in DSTYK (dual serine-threonine and tyrosine protein kinase) in all four affected family members...
February 2, 2017: American Journal of Human Genetics
https://www.readbyqxmd.com/read/28144997/explant-culture-an-advantageous-method-for-isolation-of-mesenchymal-stem-cells-from-human-tissues
#7
REVIEW
Fatemeh Hendijani
Mesenchymal stem cell (MSC) research progressively moves towards clinical phases. Accordingly, a wide range of different procedures were presented in the literature for MSC isolation from human tissues; however, there is not yet any close focus on the details to offer precise information for best method selection. Choosing a proper isolation method is a critical step in obtaining cells with optimal quality and yield in companion with clinical and economical considerations. In this concern, current review widely discusses advantages of omitting proteolysis step in isolation process and presence of tissue pieces in primary culture of MSCs, including removal of lytic stress on cells, reduction of in vivo to in vitro transition stress for migrated/isolated cells, reduction of price, processing time and labour, removal of viral contamination risk, and addition of supporting functions of extracellular matrix and released growth factors from tissue explant...
February 1, 2017: Cell Proliferation
https://www.readbyqxmd.com/read/28141717/behavioral-changes-associated-with-a-disruptive-new-student-in-the-classroom
#8
Julie Stein OʼBrien, Howard Taras, Scott Barton, Pete Sellick, Martin T Stein
Marcus is a 10-year-old boy who was followed by his pediatrician for several years. She knows him as a socially engaged, active athlete, playing soccer and baseball, out-going, and a good student. He has been in good health without a significant medical history.At the beginning of this academic year, a new student was placed in Marcus's fourth grade class. This student is disruptive, impulsive, and abusive. He has frequent violent outbursts, yelling, kicking, and throwing objects, including recently throwing a desk across the room...
February 2017: Journal of Developmental and Behavioral Pediatrics: JDBP
https://www.readbyqxmd.com/read/28138017/the-histone-chaperone-nrp1-interacts-with-werewolf-to-activate-glabra2-in-arabidopsis-root-hair-development
#9
Yan Zhu, Liang Rong, Qiang Luo, Baihui Wang, Nana Zhou, Yue Yang, Chi Zhang, Haiyang Feng, Lina Zheng, Wen-Hui Shen, Jinbiao Ma, Aiwu Dong
Nucleosome Assembly Protein 1 (NAP1) defines an evolutionarily conserved family of histone chaperones and loss-of-function of the Arabidopsis thaliana NAP1-family genes NAP1-RELATED PROTEIN 1 (NRP1) and NRP2 causes abnormal root hair formation. Yet, the underlying molecular mechanisms remain unclear. Here, we show that NRP1 interacts with the transcription factor WEREWOLF (WER) in vitro and in vivo and enriches at the GLABRA2 (GL2) promoter in a WER-dependent manner. Crystallographic analysis indicates that NRP1 forms a dimer via its N-terminal α-helix...
January 30, 2017: Plant Cell
https://www.readbyqxmd.com/read/28134037/destiny-rides-again-the-reappearance-of-silicone-gel-filled-breast-implant-toxicity
#10
A E Brawer
Background Twenty-five years ago attorneys representing ailing women in class action litigation against silicone breast implant manufacturers made the procedural error of defining silicone-induced toxicity in the courtroom before it was properly studied in the exam room. This aberrant methodology perverted the proper research process, rendered verification of any real disease elusive, and cemented the groundwork for a repeat public health crisis potentially affecting two million women in the USA who possess new silicone gel devices inserted over the past 10 years...
January 1, 2017: Lupus
https://www.readbyqxmd.com/read/28127322/a-multidisciplinary-approach-to-a-seven-year-old-patient-with-incontinentia-pigmenti-a-case-report-and-five-year-follow-up
#11
Rezvan Rafatjou, Fariborz Vafaee, Hanif Allahbakhshi, Porousha Mahjoub
Incontinentia pigmenti is a rare inherited disorder involving abnormalities of the skin, hair, eyes, musculoskeletal system, central nervous system, and the teeth. Dental abnormalities are the most common manifestations of this disorder. The purpose of this case report was to present the clinical and radiological findings of a seven-year-old girl as well as the results of her five-year follow up. The patient showed faded linear pigmented macular lesions on the trunk and on upper and lower limbs. Dental examination was notable for conical and peg-shaped anterior teeth as well as delayed eruption of primary and permanent teeth...
August 2016: Journal of Dentistry of Tehran University of Medical Sciences
https://www.readbyqxmd.com/read/28116483/facelift-approach-for-resecting-benign-upper-neck-masses
#12
Jun-Ook Park
BACKGROUND: This study evaluated the feasibility of non-magnified resection of various benign lesions of the upper neck using the facelift incision without endoscopic equipment to establish indications for the procedure. METHODS: This retrospective analysis examined 86 patients who underwent surgery for upper neck masses using the facelift incision or conventional transcervical incision at our institute between January 2012 and December 2015. RESULTS: We performed 41 operations using facelift incisions (facelift group) and 45 using conventional horizontal incisions (conventional group)...
January 23, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/28111036/an-lc-ms-ms-method-for-the-simultaneous-determination-of-15-antipsychotics-and-two-metabolites-in-hair-and-its-application-to-rat-hair
#13
Juhyun Sim, Eunmi Kim, Wonkyung Yang, Sanghee Woo, Sangwhan In
In recent years, the inappropriate use of antipsychotics by young Korean men has become a social problem. As military service exemptions are given for mental illness, some men pose as mental health patients to avoid military service. In order to verify the authenticity of mental illnesses, we developed simultaneous analytical methods for the detection of 15 antipsychotics and 2 of their metabolites in hair using liquid chromatography-tandem mass spectrometry (LC-MS/MS) analysis. The target drugs were modafinil, atomoxetine, aripiprazole, benztropine, buspirone, duloxetine, gabapentin, oxcarbazepine, topiramate, escitalopram, paliperidone, ziprasidone, lamotrigine, clonazepam, levetiracetam, and metabolites of oxcarbazepine and clonazepam...
January 12, 2017: Forensic Science International
https://www.readbyqxmd.com/read/28107576/non-invasive-anaesthetic-methods-for-dermatological-laser-procedures-a-systematic-review
#14
REVIEW
K Greveling, E P Prens, L Liu, M B A van Doorn
Pain is a common side-effect of dermatological laser procedures. Non-invasive anaesthetic drugs and anaesthetic procedures can be used to provide pain relief and increase patient satisfaction and treatment efficacy. However, it remains unclear which method provides the best pain relief. The objective of this systematic review was therefore to assess the efficacy and safety of non-invasive anaesthetic methods during dermatological laser procedures. A systematic literature search was conducted. Randomized and non-randomized controlled clinical trials (RCTs and CCTs) were included...
January 20, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28099364/endoscopic-retrieval-of-gastric-trichophytobezoar-case-report-of-a-12-year-old-girl-with-trichophagia
#15
Jiu-Ling Zhao, Wei-Chuan Zhao, Yu-Shui Wang
RATIONALE: Trichophytobezoars, which are composed of hair and plant fibers, are usually located in the stomach. They are often associated with trichophagia and trichotillomania. The most commonly reported methods of trichophytobezoar treatment are open surgery and laparoscopic retrieval; there are few reports of endoscopic removal of trichophytobezoars. PATIENT CONCERNS AND DIAGNOSES: Twelve-year-old girl presented with a 3-day history of increasing upper abdominal pain, anorexia, and postprandial emesis...
January 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28095566/prospective-evaluation-of-the-safety-and-efficacy-of-a-1060-nm-large-spot-size-vacuum-assisted-hair-removal-diode-laser-system-in-asian-pacific-fitzpatrick-s-skin-types-iv-v-patients
#16
Sushil T Tahiliani, Harsh S Tahiliani
Laser-based photoepilation of dark skin types demands a delicate combination of appropriate light wavelengths and spot size to achieve optimal epidermal-to-follicular energy absorption ratios. This prospective study assessed the axillary, arm, thigh, and back hair clearing ef cacy of the LightSheer In nity 1060 nm diode laser in 10 Fitzpatrick skin type IV-V patients. Each area was treated up to ve times, at 4-6-week intervals, after which immediate skin responses and adverse events were recorded. Hair count, color and coarseness were assessed before each treatment session, as well as 1, 3, and 6 months following the last session...
November 1, 2016: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/28095555/megasessions-for-robotic-hair-restoration
#17
Joa O Carlos Pereira, Joa O Carlos Pereira Filho, Joa O Pedro Cabrera Pereira
A robotic system can select and remove individual hair follicles from the donor area with great precision and without fatigue. This report describes the use of the robotic system in a megasession for hair restoration. Patients were instructed to cut their hair to 1.0 to 1.2 mm before surgery. The robot selected and removed 600 to 800 grafts per hour so the follicular units (FU)s could be transplanted manually to recipient sites. The robot arm consists of a sharp inner punch and a blunt outer punch which together separate FUs from the sur- rounding tissue...
November 1, 2016: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/28095543/clinical-evaluation-of-hair-removal-using-an-810-nm-diode-laser-with-a-novel-scanning-device
#18
Erin Courtney, David J Goldberg
INTRODUCTION: Diode lasers are often considered as the gold standard preference for hair removal due to the deep penetration and ef- fective targeting of the hair follicle. A wide variety of diode lasers are available, which can differ in terms of their parameters (such as fluence, pulse duration, repetition rate, scanner, and cooling). OBJECTIVE: The objective of the study was to evaluate the safety and ef cacy of hair removal with an 810 nm novel scanning diode laser, up to six months after last treatment...
November 1, 2016: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/28089708/hair-corticosterone-measurement-in-mouse-models-of-type-1-and-type-2-diabetes-mellitus
#19
Rebecca L Erickson, Caroline A Browne, Irwin Lucki
In diabetes, glucocorticoid secretion increases secondary to hyperglycemia and is associated with an extensive list of disease complications. Levels of cortisol in humans, or corticosterone in rodents, are usually measured as transitory biomarkers of stress in blood or saliva. Glucocorticoid concentrations accumulate in human or animal hair over weeks and could more accurately measure the cumulative stress burden of diseases like chronic diabetes. In this study, corticosterone levels were measured in hair in verified rodent models of diabetes mellitus...
January 12, 2017: Physiology & Behavior
https://www.readbyqxmd.com/read/28079638/the-effect-of-waxing-versus-shaving-on-the-efficacy-of-laser-hair-removal
#20
Mohammed Al-Haddab, Nour Al-Khawajah, Amal Al-Alaʼa, Hadeel Al-Majed, Yafa Al-Shamlan, Maymonah Al-Abdely
BACKGROUND: Excessive hair is undesirable and represents both a social and emotional burden, especially among females. Laser hair removal (LHR) has gained popularity in the past 2 decades. It is a common practice to instruct patients not to pluck or wax their hair before undergoing LHR; only shaving is allowed to improve the efficacy of the LHR. OBJECTIVE: To compare the percentage of hair reduction in preshaved versus prewax epilated axillae after LHR in healthy adult Saudi females...
January 10, 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
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