keyword
https://read.qxmd.com/read/38645728/mindful-monitoring-and-accepting-the-body-in-physical-activity-mediates-the-associations-between-physical-activity-and-positive-body-image-in-a-sample-of-young-physically-active-adults
#21
JOURNAL ARTICLE
Rasa Jankauskiene, Migle Baceviciene
INTRODUCTION: The study aimed to extend research on the possible mechanisms that explain the associations between physical activity (PA), mindfulness during PA and positive body image. In the present study, we tested the mediating role of state mindfulness during PA in the association between PA and trait body appreciation. We also explored the moderating roles of sex and body mass index (BMI) in these associations. METHODS: In total, 759 students participated in the study but after applying the inclusion criteria 539 questionnaires were approved for analysis, with a mean age of 23...
2024: Frontiers in sports and active living
https://read.qxmd.com/read/38645116/characterizing-nascent-transcription-patterns-of-prompts-ernas-and-readthrough-transcripts-in-the-encode4-deeply-profiled-cell-lines
#22
Ariel McShane, Ishwarya Venkata Narayanan, Michelle T Paulsen, Mario Ashaka, Hailey Blinkiewicz, Nina T Yang, Brian Magnuson, Karan Bedi, Thomas E Wilson, Mats Ljungman
Arising as co-products of canonical gene expression, transcription-associated lincRNAs, such as promoter upstream transcripts (PROMPTs), enhancer RNAs (eRNAs), and readthrough (RT) transcripts, are often regarded as byproducts of transcription, although they may be important for the expression of nearby genes. We identified regions of nascent expression of these lincRNA in 16 human cell lines using Bru-seq techniques, and found distinctly regulated patterns of PROMPT, eRNA, and RT transcription using the diverse biochemical approaches in the ENCODE4 deeply profiled cell lines collection...
April 9, 2024: bioRxiv
https://read.qxmd.com/read/38644869/unmasking-the-challenges-in-ideological-and-political-education-in-china-a-thematic-review
#23
REVIEW
Sha Ouyang, Wei Zhang, Jian Xu, Abdullah Mat Rashid, Shwu Pyng How, Aminuddin Bin Hassan
China's distinctive educational approach, particularly its emphasis on ideological and political education, has garnered considerable academic attention for its impact on shaping individual values, fostering citizenship, and maintaining social stability. Despite the Chinese government's prioritization of ideological and political education, academic research in this field appears constrained, with existing studies predominantly focusing on normative and descriptive aspects. Normative research delineates how ideological and political education should be executed, while descriptive research illustrates its practical implementation...
April 30, 2024: Heliyon
https://read.qxmd.com/read/38644601/quality-of-life-in-children-and-adolescents-after-treatment-for-acute-lymphoblastic-leukemia-according-to-the-nopho-all2008-protocol
#24
JOURNAL ARTICLE
Nina Mogensen, Ulrika Kreicbergs, Birgitte Klug Albertsen, Päivi M Lähteenmäki, Mats Heyman, Arja Harila
BACKGROUND: The improved outcome of childhood acute lymphoblastic leukemia (ALL) over the last decades has increased the importance of assessing late effects and health-related quality of life (HRQoL), particularly when evaluating and comparing outcomes in clinical trials. This study aimed to assess HRQoL in children treated for ALL according to the NOPHO ALL2008 protocol. PROCEDURE: Children, aged 1 to less than 18 years at diagnosis, alive in first remission, and their parents, were asked to complete PedsQL 4...
April 21, 2024: Pediatric Blood & Cancer
https://read.qxmd.com/read/38643985/microbiological-exploration-of-the-cueva-del-viento-lava-tube-system-in-tenerife-canary-islands
#25
JOURNAL ARTICLE
Sara Gutierrez-Patricio, Jorge R Osman, José Luis Gonzalez-Pimentel, Valme Jurado, Leonila Laiz, Alfredo Laínez Concepción, Cesareo Saiz-Jimenez, Ana Zélia Miller
Cueva del Viento, located in the Canary Islands, Spain, is the Earth's sixth-longest lava tube, spanning 18,500 m, and was formed approximately 27,000 years ago. This complex volcanic cave system is characterized by a unique geomorphology, featuring an intricate network of galleries. Despite its geological significance, the geomicrobiology of Cueva del Viento remains largely unexplored. This study employed a combination of culture-dependent techniques and metabarcoding data analysis to gain a comprehensive understanding of the cave's microbial diversity...
April 2024: Environmental Microbiology Reports
https://read.qxmd.com/read/38643460/a-novel-deep-proteomic-approach-in-human-skeletal-muscle-unveils-distinct-molecular-signatures-affected-by-aging-and-resistance-training
#26
JOURNAL ARTICLE
Michael D Roberts, Bradley A Ruple, Joshua S Godwin, Mason C McIntosh, Shao-Yung Chen, Nicholas J Kontos, Anthony Agyin-Birikorang, Max Michel, Daniel L Plotkin, Madison L Mattingly, Brooks Mobley, Tim N Ziegenfuss, Andrew D Fruge, Andreas N Kavazis
The skeletal muscle proteome alterations to aging and resistance training have been reported in prior studies. However, conventional proteomics in skeletal muscle typically yields wide protein abundance ranges that mask the detection of lowly expressed proteins. Thus, we adopted a novel deep proteomics approach whereby myofibril (MyoF) and non-MyoF fractions were separately subjected to protein corona nanoparticle complex formation prior to digestion and Liquid Chromatography Mass Spectrometry (LC-MS). Specifically, we investigated MyoF and non-MyoF proteomic profiles of the vastus lateralis muscle of younger (Y, 22±2 years old; n=5) and middle-aged participants (MA, 56±8 years old; n=6)...
April 19, 2024: Aging
https://read.qxmd.com/read/38643202/mutation-analysis-of-bcr-abl1-kinase-domain-in-chronic-myeloid-leukemia-patients-with-tyrosine-kinase-inhibitors-resistance-a-malaysian-cohort-study
#27
JOURNAL ARTICLE
Zahidah Abu Seman, Fadly Ahid, Nor Rizan Kamaluddin, Ermi Neiza Mohd Sahid, Ezalia Esa, Siti Shahrum Muhamed Said, Norazlina Azman, Wan Khairull Dhalila Wan Mat, Julia Abdullah, Nurul Aqilah Ali, Mohd Khairul Nizam Mohd Khalid, Yuslina Mat Yusoff
OBJECTIVE: Mutational analysis of BCR::ABL1 kinase domain (KD) is a crucial component of clinical decision algorithms for chronic myeloid leukemia (CML) patients with failure or warning responses to tyrosine kinase inhibitor (TKI) therapy. This study aimed to detect BCR::ABL1 KD mutations in CML patients with treatment resistance and assess the concordance between NGS (next generation sequencing) and Sanger sequencing (SS) in detecting these mutations. RESULTS: In total, 12 different BCR::ABL1 KD mutations were identified by SS in 22...
April 20, 2024: BMC Research Notes
https://read.qxmd.com/read/38643010/patient-preferences-in-genetic-newborn-screening-for-rare-diseases-study-protocol
#28
JOURNAL ARTICLE
Sylvia Martin, Emanuele Angolini, Jennifer Audi, Dr Enrico Bertini, Lucia Pia Bruno, Joshua Coulter, Alessandra Ferlini, Fernanda Fortunato, Vera Frankova, Nicolas Garnier, Åsa Grauman, Edith Gross, Brett Hauber, Mats Hansson, Janbernd Kirschner, Ferdinand Knieling, Gergana Kyosovksa, Silvia Ottombrino, Antonio Novelli, Roman Raming, Stefaan Sansen, Christina Saier, Jorien Veldwijk
INTRODUCTION: Rare diseases (RDs) collectively impact over 30 million people in Europe. Most individual conditions have a low prevalence which has resulted in a lack of research and expertise in this field, especially regarding genetic newborn screening (gNBS). There is increasing recognition of the importance of incorporating patients' needs and general public perspectives into the shared decision-making process regarding gNBS. This study is part of the Innovative Medicine Initiative project Screen4Care which aims at shortening the diagnostic journey for RDs by accelerating diagnosis for patients living with RDs through gNBS and the use of digital technologies, such as artificial intelligence and machine learning...
April 19, 2024: BMJ Open
https://read.qxmd.com/read/38642864/expression-and-biochemical-characterization-of-a-novel-thermostable-alkaline-%C3%AE-1-3-1-4-glucanase-lichenase-from-an-alkaliphilic-bacillus-lehensis-g1
#29
JOURNAL ARTICLE
Noor Liana Mat Yajit, Noor Haza Fazlin Hashim, Rosli Mohd Illias, Abdul Munir Abdul Murad
New thermostable β-1,3-1,4-glucanase (lichenase) designated as Blg29 was expressed and purified from a locally isolated alkaliphilic bacteria Bacillus lehensis G1. The genome sequence of B. lehensis predicted an open reading frame of Blg29 with a deduced of 249 amino acids and a molecular weight of 28.99 kDa. The gene encoding for Blg29 was successfully amplified via PCR and subsequently expressed as a recombinant protein using the E. coli expression system. Recombinant Blg29 was produced as a soluble form and further purified via immobilized metal ion affinity chromatography (IMAC)...
April 18, 2024: Protein Expression and Purification
https://read.qxmd.com/read/38642696/implementation-of-perinatal-quality-collaborative-statewide-initiative-improves-obstetric-opioid-use-disorder-care-and-outcomes
#30
JOURNAL ARTICLE
Patricia A Lee King, SuYeon Lee, Dan Weiss, David Aaby, Tamela Milan-Alexander, Ann Eb Borders
BACKGROUND: Maternal deaths resulting from opioid use disorder (OUD) have been rising across the United States​. OUD among pregnant persons is associated with adverse pregnancy outcomes including preterm birth along with racial disparities in optimal OUD care. OBJECTIVE: We aimed to evaluate whether the Illinois Perinatal Quality Collaborative's (ILPQC) implementation of the Mothers and Newborns affected by Opioids - Obstetric quality improvement initiative was associated with improvement of OUD identification, provision of optimal OUD care for birthing patients, and reduction in racial gaps of optimal OUD care...
April 18, 2024: American Journal of Obstetrics and Gynecology
https://read.qxmd.com/read/38642068/improvements-of-mid-thigh-circumferences-following-robotic-rehabilitation-in-hemiparetic-stroke-patients
#31
JOURNAL ARTICLE
Nur Fasihah Mat Nawi, Anna Alicia Simok, Muhammad Hafiz Hanafi, Zul Izhar Mohd Ismail
INTRODUCTION: Stroke has emerged as the leading cause of disability globally. The provision of long-term rehabilitation to stroke survivors poses a health care burden to many countries. Robotic devices have created a major turning point in stroke rehabilitation program. Currently, the anthropometric evidence to support the benefit of robotic rehabilitation (RR) among stroke patients is scarce. Therefore, the aim of this study was to evaluate the impact of RR on the mid-thigh circumferences of the paretic limbs in stroke patients...
April 2024: Physiotherapy Research International: the Journal for Researchers and Clinicians in Physical Therapy
https://read.qxmd.com/read/38641869/walking-together-in-friendship-learning-about-cultural-safety-in-mainstream-mental-health-services-through-aboriginal-participatory-action-research
#32
JOURNAL ARTICLE
Helen Milroy, Shraddha Kashyap, Jemma Collova, Michael Mitchell, Angela Ryder, Zacharia Cox, Mat Coleman, Michael Taran, Beatriz Cuesta Briand, Graham Gee
OBJECTIVE: Culturally safe service provision is essential to improving social and emotional wellbeing among Aboriginal and Torres Strait Islander communities, and to eliminating health inequities. Cultural safety is about ensuring that all people have a safe and healing journey through services, regardless of their cultural background. In this project, we aim to (1) understand how Aboriginal and Torres Strait Islander peoples conceptualise cultural safety, and (2) co-design a qualitative interview for the next phase of this project, where we plan to learn about experiences of cultural safety within mental health services...
April 19, 2024: Australian and New Zealand Journal of Psychiatry
https://read.qxmd.com/read/38641497/leptospira-specific-immunoglobulin-y-igy-is-protective-in-infected-hamsters
#33
JOURNAL ARTICLE
Tianbao Lv, Xufeng Xie, Luteng Diao, Shuang Jiang, Yue Ding, Xin Yuan, Lingling Gong, Xi Chen, Wenlong Zhang, Yongguo Cao
Leptospirosis, a globally significant zoonotic disease caused by pathogenic Leptospira, continues to threaten the health and public safety of both humans and animals. Current clinical treatment of leptospirosis mainly relies on antibiotics but their efficacy in severe cases is controversial. Passive immunization has a protective effect in the treatment of infectious diseases. In addition, chicken egg yolk antibody (IgY) has gained increasing attention as a safe passive immunization agent. This study aimed to investigate whether hens produce specific IgY after immunization with inactivated Leptospira and the protective effect of specific IgY against leptospirosis...
April 18, 2024: Vaccine
https://read.qxmd.com/read/38640762/effects-on-food-intake-of-gammarus-spp-after-exposure-to-pfba-in-very-low-concentrations
#34
JOURNAL ARTICLE
Tove Porseryd, Josefine Larsson, Johanna Lindman, Erica Malmström, Katarzyna Smolarz, Mats Grahn, Patrik Dinnétz
Per- and polyfluoroalkyl substances (PFAS) are a group of thousands of highly persistent anthropogenic chemicals widely used in many industries. Therefore, they are, ubiquitously present in various types of environments. Despite their omnipresence, ecotoxicological studies of most PFAS are scarce, and those available often assess the effects of long chain PFAS. In this study, we present the results of an exposure experiment in which wild aquatic amphipod Gammarus spp. was exposed to the short chain perfluorinated substance perfluorobutanoic acid (PFBA) at very low and environmentally relevant concentrations of 0, 10 and 100 ng/L...
April 18, 2024: Marine Pollution Bulletin
https://read.qxmd.com/read/38639284/a-video-based-automated-tracking-and-analysis-system-of-plaque-burden-in-carotid-artery-using-deep-learning-a-comparison-with-senior-sonographers
#35
JOURNAL ARTICLE
Wenjing Gao, Mengmeng Liu, Jinfeng Xu, Shaofu Hong, Jiayi Chen, Chen Cui, Siyuan Shi, Yinghui Dong, Di Song, Fajin Dong
BACKGROUND AND OBJECTIVE: The incidence of stroke is rising, and it is the second major cause of mortality and the third leading cause of disability around the globe. The goal of this study was to rapidly and accurately identify carotid plaques and automatically quantify plaque burden using our automated tracking and segmentation US-video system. METHODS: We collected 88 common carotid artery transection videos (11048 frames) with a history of atherosclerosis or risk factors for atherosclerosis, which were randomly divided into training, test, and validation sets using a 6:3:1 ratio...
April 18, 2024: Current medical imaging
https://read.qxmd.com/read/38638580/%C3%AF-indigoferajintongpenensis-fabaceae-papilionoideae-indigofereae-a-new-species-from-yunnan-southwest-china
#36
JOURNAL ARTICLE
Lan Yao, Yan Yang, Xue-Li Zhao, Qiu-Ping Wang, Huan-Chong Wang
Indigoferajintongpenensis , a new species of the subfamily Papilionoideae of Fabaceae, is described and illustrated from Yunnan, southwest China. The new species is characterised by having a prostrate habit, flexible stems and branches, as well as spreading, sub-basifixed, asymmetrically 2-branched trichomes covering the entire plant, discoid calyx, and racemose inflorescences 6-8-flowered, short, 1-2 (-3.5) cm in length, apparently shorter than the leaf. A distribution map and comparison of morphological diagnostic characters with its morphologically similar species are provided...
2024: PhytoKeys
https://read.qxmd.com/read/38637778/associations-between-47-anthropometric-markers-derived-from-a-body-scanner-and-relative-fat-free-mass-in-a-population-based-study
#37
JOURNAL ARTICLE
Maximilian Dietzmann, Dörte Radke, Marcello Rp Markus, Mats Wiese, Henry Völzke, Stephan B Felix, Marcus Dörr, Martin Bahls, Till Ittermann
BACKGROUND: Low relative fat free mass (FFM) is associated with a greater risk of chronic diseases and mortality. Unfortunately, FFM is currently not being measured regularly to allow for individuals therapy. OBJECTIVE: One reason why FFM is not being used may be related to additional equipment and resources, thus we aimed to identify easily accessible anthropometric markers related with FFM. MATERIALS AND METHODS: We analyzed data of 1,593 individuals (784 women; 49...
April 18, 2024: BMC Public Health
https://read.qxmd.com/read/38636807/a-pilot-randomized-controlled-trial-of-medication-adherence-therapy-psychosocial-leverage-using-a-significant-other-mat-plus-for-individuals-on-extended-release-naltrexone
#38
JOURNAL ARTICLE
Kevin Wenzel, Julia Thomas, Jennifer Carrano, Jennifer Stidham, Marc Fishman
BACKGROUND: Extended-release naltrexone (XR-NTX) is an important treatment option for individuals with opioid use disorder (OUD) and/or alcohol use disorder (AUD). However, problems with retention are a major barrier to its overall effectiveness, and interventions to improve adherence are underdeveloped. The purpose of this study was to pilot test the MAT-PLUS intervention, which combines assertive outreach and involvement of a treatment significant other (TSO) to improve adherence to XR-NTX...
April 15, 2024: J Subst Use Addict Treat
https://read.qxmd.com/read/38636751/development-of-toxic-gas-sensor-from-anthocyanin-embedded-polycaprolactone-co-polylactic-acid-nanofibrous-mat
#39
JOURNAL ARTICLE
Salhah D Al-Qahtani, Ghadah M Al-Senani
The colorless ammonia gas has been a significant intermediate in the industrial sector. However, prolonged exposure to ammonia causes harmful effects to organs or even death. Herein, an environmentally friendly solid-state ammonia sensor was developed utilizing colorimetric polycaprolactone-co-polylactic acid nanofibrous membrane. Pomegranate (Punica granatum L.) peel contains anthocyanin (ACN) as a naturally occurring spectroscopic probe. A mordant (potassium aluminum sulfate) is used to immobilize the anthocyanin direct dyestuff inside nanofibers, generating mordant/anthocyanin (M/ACN) coordinated complex nanoparticles...
April 15, 2024: International Journal of Biological Macromolecules
https://read.qxmd.com/read/38636474/genetic-susceptibility-variants-of-vascular-dementia-among-asians-a-systematic-review-and-meta-analysis
#40
Vasudevan Ramachandran, Nur Afiqah Mohamad, Mohd Nazil Salleh, Wan Aliaa Wan Sulaiman, Liyana Najwa Inche Mat, Mohd Hazmi Mohamed, Ching Siew Mooi, Abdul Hanif Khan Yusof Khan, Hamidon Basri, Pannerselvam Periasamy, Vajiravelu Suganthi, Narenkumar Jayaraman
INTRODUCTION: Vascular dementia (VaD), a neurocognitive impairment directly related to vascular injury, is the second most common cause of age-related dementia. Although numerous studies have investigated candidate genetic polymorphisms associated with VaD in Asia, the genetics of VaD remains unclear. METHODS: This review provides an updated meta-analysis of genetic polymorphisms associated with VaD in Asians, using the PRISMA guidelines. Published literature up to May 2021 was extracted from the PubMed, Scopus, Ovid, and EBSCO host databases...
April 18, 2024: Dementia and Geriatric Cognitive Disorders
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