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https://www.readbyqxmd.com/read/28822930/spatial-and-temporal-patterns-of-pesticide-concentrations-in-streamflow-drainage-and-runoff-in-a-small-swedish-agricultural-catchment
#1
Maria Sandin, Kristin Piikki, Nicholas Jarvis, Mats Larsbo, Kevin Bishop, Jenny Kreuger
A better understanding of the dominant source areas and transport pathways of pesticide losses to surface water is needed for targeting mitigation efforts in a more cost-effective way. To this end, we monitored pesticides in surface water in an agricultural catchment typical of one of the main crop production regions in Sweden. Three small sub-catchments (88-242ha) were selected for water sampling based on a high-resolution digital soil map developed from proximal sensing methods and soil sampling; one sub-catchment had a high proportion of clay soils, another was dominated by coarse sandy soils while the third comprised a mix of soil types...
August 17, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28822140/optical-fiber-bragg-grating-instrumented-silicone-liner-for-interface-pressure-measurement-within-prosthetic-sockets-of-lower-limb-amputees
#2
Ebrahim Al-Fakih, Nooranida Arifin, Gholamhossein Pirouzi, Faisal Rafiq Mahamd Adikan, Hanie Nadia Shasmin, Noor Azuan Abu Osman
This paper presents a fiber Bragg grating (FBG)-instrumented prosthetic silicone liner that provides cushioning for the residual limb and can successfully measure interface pressures inside prosthetic sockets of lower-limb amputees in a simple and practical means of sensing. The liner is made of two silicone layers between which 12 FBG sensors were embedded at locations of clinical interest. The sensors were then calibrated using a custom calibration platform that mimics a real-life situation. Afterward, a custom gait simulating machine was built to test the liner performance during an amputee's simulated gait...
August 2017: Journal of Biomedical Optics
https://www.readbyqxmd.com/read/28821552/differences-in-temperature-and-water-chemistry-shape-distinct-diversity-patterns-in-thermophilic-microbial-communities
#3
Cecilia M Chiriac, Edina Szekeres, Knut Rudi, Andreea Baricz, Adriana Hegedus, Nicolae Dragoş, Cristian Coman
This study presents the biodiversity and ecology of microbial mats developed in thermal gradients (20-65 °C) in the surroundings of three drillings (CH, CI, MB) tapping a hyperthermal aquifer from Romania. Using a metabarcoding approach, 16S rRNA genes were sequenced from both DNA and RNA transcripts (cDNA) and compared. The relationships between the microbial diversity and the physico-chemical factors were explored. Additionally, the cDNA data was used for in silico functionality predictions, bringing new insights into the functional potential and dynamics of these communities...
August 18, 2017: Applied and Environmental Microbiology
https://www.readbyqxmd.com/read/28821472/surgical-findings-and-outcomes-in-premenopausal-breast-cancer-patients-undergoing-oophorectomy-a-multicenter-review-from-the-fellows-pelvic-research-network
#4
Lara F B Harvey, Vandana G Abramson, Jimena Alvarez, Christopher Destephano, Hye-Chun Hur, Katherine Lee, Patricia Mattingly, Beau Park, Carolyn Piszczek, Farinaz Seifi, Mallory Stuparich, Amanda Yunker
STUDY OBJECTIVE: Since publication of the Suppression of Ovarian Function Trial (SOFT) data, some women with premenopausal breast cancer have been recommended to undergo bilateral oophorectomy to facilitate breast cancer treatment with aromatase inhibitors. These women may be at higher risk of occult abdominal pathology than the general population. Our objective is to describe the procedures performed, intra-abdominal findings, and surgical pathology of this population. DESIGN: Multi-center retrospective chart review...
August 15, 2017: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/28821109/pectinate-nanofiber-mat-with-high-absorbency-and-antibacterial-activity-a-potential-superior-wound-dressing-to-alginate-and-chitosan-nanofiber-mats
#5
Sainan Chen, Sisi Cui, Junli Hu, Yifa Zhou, Yichun Liu
Polysaccharides including pectin, alginate and chitosan are fabricated into dressings of micrometer-scaled architecture (micro- fiber or particle) and widely applied in wound treatments clinically. This work characterized and compared the properties of electrospun nanofibrous dressings of these polysaccharides. We found that although the three polysaccharide nanofiber mats had comparable mechanical strength and vapour permeability, the pectinate nanofiber mat could absorb 1.2 times and 3.6 times more exudates than the alginate and chitosan nanofiber mats, respectively, within less time...
October 15, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28820476/biosynthesis-of-s-adenosylmethionine-by-magnetically-immobilized-escherichia-coli-cells-highly-expressing-a-methionine-adenosyltransferase-variant
#6
Chunli Yin, Tao Zheng, Xin Chang
S-Adenosylmethionine (SAM) is a natural metabolite having important uses in the treatment of various diseases. To develop a simple and effective way to produce SAM, immobilized Escherichia coli cells highly expressing an engineered variant of methionine adenosyltransferase (MAT) were employed to synthesize SAM. The recombinant I303V MAT variant was successfully produced at approximately 900 mg/L in a 10-L bioreactor and exhibited significantly less product inhibition and had a four-fold higher specific activity (14...
August 18, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28819011/tp53-mutations-identify-younger-mantle-cell-lymphoma-patients-who-do-not-benefit-from-intensive-chemoimmunotherapy
#7
Christian W Eskelund, Christina Dahl, Jakob W Hansen, Maj Westman, Arne Kolstad, Lone B Pedersen, Carmen P Montano-Almendras, Simon Husby, Catja Freiburghaus, Sara Ek, Anja Pedersen, Carsten Niemann, Riikka Räty, Peter Brown, Christian H Geisler, Mette K Andersen, Per Guldberg, Mats Jerkeman, Kirsten Grønbæk
Despite recent advances in lymphoma treatment, mantle cell lymphoma (MCL) remains incurable and we are still unable to identify patients who will not benefit from the current standard-of-care. Here, we explore the prognostic value of recurrent genetic aberrations in diagnostic bone marrow (BM) specimens from 183 younger MCL patients from the Nordic MCL2 and MCL3 trials, which represent current standard-of-care regimens. In the univariate model, mutations of TP53 (11%) and NOTCH1 (4%), and deletions of TP53 (16%) and CDKN2A (20%) were significantly associated with inferior outcomes (together with MIPI, MIPI-c, Blastoid morphology and Ki67>30%); however, in multivariate analyses only TP53 mutations (HR=6...
August 17, 2017: Blood
https://www.readbyqxmd.com/read/28817942/-the-current-status-of-diagnostic-tools-for-leptospirosis
#8
Mitsumasa Saito, Yasuhiko Nikaido, Masahiro Matsumoto, Midori Ogawa, Sharon Y A M Villanueva
Leptospirosis is a worldwide zoonosis caused by pathogenic Leptospira spp. The severity of leptospirosis vary from mild, flu-like disease to a more severe form, Weil's disease causing jaundice, hemorrhage, renal failure, and even death. Every year, 300,000‒500,000 cases of severe leptospirosis are reported around the world, with the case fatality rate being 10‒30%. The usual diagnostic tools for leptospirosis are 1) direct observation of leptospires in blood and urine under dark-field microscope, 2) isolation of leptospires from blood, cerebrospinal fluid (CSF), or urine samples by culture, 3) microscopic agglutination test (MAT) to detect anti-Leptospira antibodies in serum, and 4) PCR to detect Leptospira DNA...
August 15, 2017: JARMAM: Journal of the Association for Rapid Method and Automation in Microbiology
https://www.readbyqxmd.com/read/28817294/heterogeneity-of-nonadherent-buprenorphine-patients-subgroup-characteristics-and-outcomes
#9
Charles Ruetsch, Joseph Tkacz, Vijay R Nadipelli, Brenna L Brady, Naoko Ronquest, Hyong Un, Joseph Volpicelli
OBJECTIVES: To examine patient characteristics and outcomes associated with nonadherence to buprenorphine and to identify specific patterns of nonadherent behavior. STUDY DESIGN: Cross-sectional, retrospective analysis of health claims data. METHODS: Aetna's administrative claims data were used to categorize incident opioid use disorder (OUD) patients based on buprenorphine medication possession ratio (MPR) into adherent (n = 172) and nonadherent (n = 305) groups...
June 1, 2017: American Journal of Managed Care
https://www.readbyqxmd.com/read/28816515/how-should-we-secure-our-transplanted-meniscus-a-meta-analysis
#10
Julio J Jauregui, Zhan Dong Wu, Sean Meredith, Cullen Griffith, Jonathan D Packer, R Frank Henn
BACKGROUND: Meniscal allograft transplant (MAT) is a salvage procedure for young patients with symptomatic meniscal deficiency. Although many studies report good outcomes, MAT remains controversial, and an optimal fixation technique for the meniscus roots is debated. PURPOSE: To assess the overall outcome of MAT and compare the results of different meniscal root fixation techniques. STUDY DESIGN: Meta-analysis. METHODS: Following specific guidelines, we systematically evaluated all current literature for studies reporting on the outcomes of patients who underwent MAT...
August 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28815079/implementation-of-minimally-invasive-esophagectomy-in-a-tertiary-referral-center-for-esophageal-cancer
#11
Magnus Nilsson, Satoshi Kamiya, Mats Lindblad, Ioannis Rouvelas
BACKGROUND: Esophagectomy remains the gold standard in the curative intent treatment of resectable esophageal cancer. However, this procedure is complex and associated with high risk of complications. In an effort to reduce the postoperative morbidity associated with open esophagectomy various minimally invasive techniques have been introduced and developed during the recent years. The aim of the current study was to present our 4.5-year experience of the gradual implementation of various minimally invasive esophagectomy (MIE) techniques in our tertiary referral center...
July 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28814932/achievement-of-ldl-cholesterol-goal-and-adherence-to-statin-by-diabetes-patients-in-kelantan
#12
Zainab Mat Yudin, Lili Husniati Yaacob, Norul Badriah Hassan, Saiful Bahari Ismail, Nani Draman, Siti Suhaila Mohd Yusoff
BACKGROUND: Statins are a class of potent drugs that can be used to reduce cholesterol, especially low-density lipoprotein cholesterol (LDL-C). However, their effectiveness is limited if adherence to treatment is poor. The objectives of the study are to estimate the proportion of diabetic patient who has achieved LDL-C goal and to determine the association of LDL-C achievement with socio demographic factors and statin therapy adherence. METHODS: This is a cross-sectional study involving 234 patients with type 2 diabetes mellitus (T2DM) and dyslipidaemia attending an outpatient clinic in a hospital in Kelantan...
May 2017: Malaysian Journal of Medical Sciences: MJMS
https://www.readbyqxmd.com/read/28813235/temporary-hearing-threshold-shift-in-healthy-volunteers-with-hearing-protection-caused-by-acoustic-noise-exposure-during-3-t-multisequence-mr-neuroimaging
#13
Chao Jin, Huan Li, Xianjun Li, Miaomiao Wang, Congcong Liu, Jianxin Guo, Jian Yang
Purpose To determine whether a single 51-minute exposure to acoustic noise during 3-T multisequence magnetic resonance (MR) neuroimaging could affect the hearing threshold of healthy adults with earplugs and sponge mats as hearing protection. Materials and Methods With earplugs and motion-refraining sponge mats as hearing protection, 26 healthy young adults underwent 3-T MR neuroimaging imaging that included T1-weighted three-dimensional gradient-echo sequence, T2-weighted fast spin-echo sequence, diffusion-tensor imaging, diffusion-kurtosis imaging, T2*-weighted three-dimensional multiecho gradient-echo sequence, and blood oxygen level-dependent imaging...
August 16, 2017: Radiology
https://www.readbyqxmd.com/read/28812874/three-dimensional-highly-stretchable-conductors-from-elastic-fiber-mat-with-conductive-polymer-coating
#14
Shasha Duan, Zhihui Wang, Ling Zhang, Jin Liu, Chunzhong Li
The manufacture of stretchable conductors with well-reserved electrical performance under large-degree deformations via scalable processes remains of great importance. In this work, a highly stretchable 3D conductive framework consisted of polyurethane fiber mat (PUF) and poly(3,4-ethylenedioxythiophene) (PEDOT) is reported through facile approaches, electrospinning and in situ interfacial polymerization, which was then backfilled with poly(dimethylsiloxane) to obtain 3D conductors. The excellent stretchability of the 3D conductive network imparted the as-prepared electrode superior mechanical durability...
August 16, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28812643/a-submarine-volcanic-eruption-leads-to-a-novel-microbial-habitat
#15
Roberto Danovaro, Miquel Canals, Michael Tangherlini, Antonio Dell'Anno, Cristina Gambi, Galderic Lastras, David Amblas, Anna Sanchez-Vidal, Jaime Frigola, Antoni M Calafat, Rut Pedrosa-Pàmies, Jesus Rivera, Xavier Rayo, Cinzia Corinaldesi
Submarine volcanic eruptions are major catastrophic events that allow investigation of the colonization mechanisms of newly formed seabed. We explored the seafloor after the eruption of the Tagoro submarine volcano off El Hierro Island, Canary Archipelago. Near the summit of the volcanic cone, at about 130 m depth, we found massive mats of long, white filaments that we named Venus's hair. Microscopic and molecular analyses revealed that these filaments are made of bacterial trichomes enveloped within a sheath and colonized by epibiotic bacteria...
April 24, 2017: Nature ecology & evolution
https://www.readbyqxmd.com/read/28810478/brief-report-contemplate-your-symptoms-and-re-evaluate-your-health-a-study-on-working-adults
#16
Anna Andreasson, Helena Schiller, Torbjörn Åkerstedt, Erik Berntson, Göran Kecklund, Mats Lekander
We investigated whether self-ratings of health are affected by a symptom rating. A diary including a one-item self-rating of health ("pre-self-rated health"; 1 = excellent, 7 = very poor), a subsequent 26-item rating of symptoms, and thereafter a second (identical) health rating ("post-self-rated health") was completed by 820 persons 21 times. Self-rated health worsened significantly ( p < .0001) after the symptom rating, from 2.72 pre-self-rated health (95% confidence interval: 2.70-2.74) to 2...
June 1, 2017: Journal of Health Psychology
https://www.readbyqxmd.com/read/28808883/removal-of-water-soluble-extractives-improves-the-enzymatic-digestibility-of-steam-pretreated-softwood-barks
#17
Balázs Frankó, Karin Carlqvist, Mats Galbe, Gunnar Lidén, Ola Wallberg
Softwood bark contains a large amounts of extractives-i.e., soluble lipophilic (such as resin acids) and hydrophilic components (phenolic compounds, stilbenes). The effects of the partial removal of water-soluble extractives before acid-catalyzed steam pretreatment on enzymatic digestibility were assessed for two softwood barks-Norway spruce and Scots pine. A simple hot water extraction step removed more than half of the water-soluble extractives from the barks, which improved the enzymatic digestibility of both steam-pretreated materials...
August 14, 2017: Applied Biochemistry and Biotechnology
https://www.readbyqxmd.com/read/28808812/antioxidant-effects-of-chrysin-loaded-electrospun-nanofibrous-mats-on-proliferation-and-stemness-preservation-of-human-adipose-derived-stem-cells
#18
Yaghoub Deldar, Faraz Zarghami, Younes Pilehvar-Soltanahmadi, Mehdi Dadashpour, Nosratollah Zarghami
An ideal biomaterial in regenerative medicine should be able to regulate the stem cell proliferation without the loss of its pluripotency. Chrysin (Chr) is a naturally occurring flavone with a wide spectrum of biological functions including anti-inflammatory and anti-oxidant properties. The present study describes the influence of Chr-loaded nanofibrous mats on the regulation of proliferation and stemness preservation of adipose-derived stem cells (ADSCs). For this purpose, Chr-loaded poly (ε-caprolactone)/poly (ethylene glycol) (PCL/PEG) nanofibrous mats were produced via electrospinning process and the successful fabrication of these bioactive mats was confirmed by field emission scanning electron microscopy (FE-SEM) and fourier transform infrared spectroscopy...
August 14, 2017: Cell and Tissue Banking
https://www.readbyqxmd.com/read/28807274/isolation-of-viable-toxoplasma-gondii-molecular-characterization-and-seroprevalence-in-elk-cervus-canadensis-in-pennsylvania-usa
#19
J P Dubey, J Brown, S K Verma, C K Cerqueira-Cézar, J Banfield, O C H Kwok, Y Ying, F H A Murata, A K Pradhan, C Su
Toxoplasmosis is a worldwide zoonosis. The ingestion of uncooked/undercooked meat and consumption of water contaminated with Toxoplasma gondii oocysts excreted by felids are the main modes of transmission of this parasite. T. gondii has been reported in multiple cervid species; however, little is known of the parasite in North American elk (Cervus canadensis). In the present study, antibodies to T. gondii were detected in serum of wild elk from Pennsylvania collected during 2013-2016 by the modified agglutination test (MAT, cut-off 1:25); 221 of 317 (69...
August 30, 2017: Veterinary Parasitology
https://www.readbyqxmd.com/read/28807200/a-sequential-assessment-of-the-preservation-injury-in-porcine-intestines
#20
Mihai Oltean, Lucian Jiga, Mats Hellström, John Söfteland, Marius Papurica, Teodora Hoinoiu, Mihai Ionac, Anna Casselbrant
BACKGROUND: Clinical and experimental evidence strongly suggest that ischemia-reperfusion injury after intestinal transplantation has deleterious short- and long-term effects and finding means to reduce ischemia-reperfusion injury is a major research area. The anatomical and physiological similarities between the human and porcine digestive tract favor its use as a preclinical model for translational research. Intriguingly, no systematic appraisal of the development of the intestinal preservation injury in pigs is available...
August 2017: Journal of Surgical Research
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