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https://www.readbyqxmd.com/read/28430735/sodium-tetradecyl-sulfate-a-review-of-clinical-uses
#1
Helena A Jenkinson, Kelly M Wilmas, Sirunya Silapunt
BACKGROUND: Sodium tetradecyl sulfate (STS) is Food and Drug Administration approved for treatment of varicose veins, but numerous other off-label applications have been reported. OBJECTIVE: To describe the clinical uses of STS, as well as efficacy and adverse effects. METHODS: Review of studies searchable on PubMed from 1938 to 2016 describing clinical uses of STS to determine efficacy and adverse effects associated with various applications...
April 19, 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/28428847/lichen-acclimation-to-changing-environments-photobiont-switching-vs-climate-specific-uniqueness-in-psora-decipiens
#2
Laura Williams, Claudia Colesie, Anna Ullmann, Martin Westberg, Mats Wedin, Burkhard Büdel
Unraveling the complex relationship between lichen fungal and algal partners has been crucial in understanding lichen dispersal capacity, evolutionary processes, and responses in the face of environmental change. However, lichen symbiosis remains enigmatic, including the ability of a single fungal partner to associate with various algal partners. Psora decipiens is a characteristic lichen of biological soil crusts (BSCs), across semi-arid, temperate, and alpine biomes, which are particularly susceptible to habitat loss and climate change...
April 2017: Ecology and Evolution
https://www.readbyqxmd.com/read/28428541/tissue-engineered-cornea-constructed-with-compressed-collagen-and-laser-perforated-electrospun-mat
#3
Bin Kong, Wei Sun, Guoshi Chen, Song Tang, Ming Li, Zengwu Shao, Shengli Mi
While Plastic Compressed (PC) collagen technique is often used to fabricate bioengineered constructs, PC collagen gels are too weak to be sutured or conveniently handled for clinical applications. To overcome this limitation, electrospun poly (lactic-co-glycolide) (PLGA) mats, which have excellent biocompatibility and mechanical properties, were combined with PC collagen to fabricate sandwich-like hybrid constructs. By laser-perforating holes with different sizes and spacings in the electrospun mats to regulate the mechanical properties and light transmittance of the hybrid constructs, we produced hybrid constructs with properties very suitable to apply in corneal tissue engineering...
April 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28428364/role-of-oestrogen-receptor-signaling-in-skeletal-response-to-leptin-in-female-ob-ob-mice
#4
Russell T Turner, Kenneth A Philbrick, Amida Kuah, Adam J Branscum, Urszula T Iwaniec
Leptin, critical in regulation of energy metabolism, is also important for normal bone growth, maturation and turnover. Compared to wild type (WT) mice, bone mass is lower in leptin-deficient ob/ob mice; osteopenia in growing ob/ob mice is due to decreased bone accrual, and is associated with reduced longitudinal bone growth, impaired cancellous bone maturation and increased marrow adipose tissue (MAT). However, leptin deficiency also results in gonadal dysfunction, disrupting production of gonadal hormones which regulate bone growth and turnover...
April 20, 2017: Journal of Endocrinology
https://www.readbyqxmd.com/read/28427478/morphological-and-molecular-characteristics-of-malayfilaria-sofiani-uni-mat-udin-takaoka-n-g-n-sp-nematoda-filarioidea-from-the-common-treeshrew-tupaia-glis-diard-duvaucel-mammalia-scandentia-in-peninsular-malaysia
#5
Shigehiko Uni, Ahmad Syihan Mat Udin, Takeshi Agatsuma, Weerachai Saijuntha, Kerstin Junker, Rosli Ramli, Hasmahzaiti Omar, Yvonne Ai-Lian Lim, Sinnadurai Sivanandam, Emilie Lefoulon, Coralie Martin, Daicus Martin Belabut, Saharul Kasim, Muhammad Rasul Abdullah Halim, Nur Afiqah Zainuri, Subha Bhassu, Masako Fukuda, Makoto Matsubayashi, Masashi Harada, Van Lun Low, Chee Dhang Chen, Narifumi Suganuma, Rosli Hashim, Hiroyuki Takaoka, Mohd Sofian Azirun
BACKGROUND: The filarial nematodes Wuchereria bancrofti (Cobbold, 1877), Brugia malayi (Brug, 1927) and B. timori Partono, Purnomo, Dennis, Atmosoedjono, Oemijati & Cross, 1977 cause lymphatic diseases in humans in the tropics, while B. pahangi (Buckley & Edeson, 1956) infects carnivores and causes zoonotic diseases in humans in Malaysia. Wuchereria bancrofti, W. kalimantani Palmieri, Pulnomo, Dennis & Marwoto, 1980 and six out of ten Brugia spp. have been described from Australia, Southeast Asia, Sri Lanka and India...
April 20, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/28427270/skin-irritation-testing-of-antimicrobial-conjugated-electrolytes
#6
Kristin N Wilde, Phuong A H Nguyen, David G Whitten, Heather E Canavan
Each year, the United States spends about $20 billion to treat people who have been infected with antibiotic resistant bacteria. Even so, the development of new antibiotics has slowed considerably since the mid-20th century. As a result, researchers are looking into developing synthetic compounds and materials with antimicrobial activities such as those made by the Schanze and Whitten groups [ACS Appl. Mater. Interfaces 3, 2820 (2011)]. Previously, they have demonstrated that poly(phenylene ethynylene) (PPE) based electrolytes and oligomeric end-only phenylene ethynylene (EO-OPE) based electrolytes possess strong biocidal activity...
April 20, 2017: Biointerphases
https://www.readbyqxmd.com/read/28425778/meditation-awareness-training-for-the-treatment-of-workaholism-a-controlled-trial
#7
William Van Gordon, Edo Shonin, Thomas J Dunn, Javier Garcia-Campayo, Marcelo M P Demarzo, Mark D Griffiths
Background and aims Workaholism is a form of behavioral addiction that can lead to reduced life and job satisfaction, anxiety, depression, burnout, work-family conflict, and impaired productivity. Given the number of people affected, there is a need for more targeted workaholism treatments. Findings from previous case studies successfully utilizing second-generation mindfulness-based interventions (SG-MBIs) for treating behavioral addiction suggest that SG-MBIs may be suitable for treating workaholism. This study conducted a controlled trial to investigate the effects of an SG-MBI known as meditation awareness training (MAT) on workaholism...
April 20, 2017: Journal of Behavioral Addictions
https://www.readbyqxmd.com/read/28425479/perturbed-oral-motor-control-due-to-anesthesia-during-intraoral-manipulation-of-food
#8
Joannis Grigoriadis, Abhishek Kumar, Peter Svensson, Krister G Svensson, Mats Trulsson
Sensory information from periodontal mechanoreceptors (PMRs) surrounding the roots of natural teeth is important for optimizing the positioning of food and adjustment of force vectors during precision biting. The present experiment was designed to test the hypothesis; that reduction of afferent inputs from the PMRs, by anesthesia, perturbs the oral fine motor control and related jaw movements during intraoral manipulation of morsels of food. Thirty healthy volunteers with a natural dentition were equally divided into experimental and control groups...
April 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28425158/sexual-colouration-and-sperm-performance-in-the-australian-painted-dragon-lizard-ctenophorus-pictus
#9
Callum S McDiarmid, Christopher R Friesen, Cissy Ballen, Mats Olsson
Theory predicts trade-offs between pre- and postcopulatory sexually selected traits. This relationship may be mediated by the degree to which males are able to monopolise access to females, as this will place an upper limit on the strength of postcopulatory selection. Furthermore, traits that aid in mate monopolization may be costly to maintain and may limit investment in postcopulatory traits, such as sperm performance. Australian painted dragons are polymorphic for the presence or absence of a yellow gular patch ('bibs'), which may aid them to monopolise access to females...
April 20, 2017: Journal of Evolutionary Biology
https://www.readbyqxmd.com/read/28424285/equine-arteritis-virus-has-specific-tropism-for-stromal-cells-and-cd8-t-and-cd21-b-lymphocytes-but-not-glandular-epithelium-at-the-primary-site-of-persistent-infection-in-the-stallion-reproductive-tract
#10
Mariano Carossino, Alan T Loynachan, Igor F Canisso, R Frank Cook, Juliana R Campos, Bora Nam, Yun Young Go, Edward L Squires, Mats H T Troedsson, Thomas Swerczek, Fabio Del Piero, Ernest Bailey, Peter J Timoney, Udeni B R Balasuriya
Equine arteritis virus (EAV) has a global impact on the equine industry being the causative agent of equine viral arteritis (EVA), a respiratory, systemic, and reproductive disease of equids. A distinctive feature of EAV infection is that it establishes long-term persistent infection in 10 to 70% of infected stallions (carriers). In these stallions, EAV is only detectable in the reproductive tract and viral persistence occurs despite the presence of high serum neutralizing antibodies. Carrier stallions constitute the natural reservoir of the virus as they continuously shed EAV in their semen...
April 19, 2017: Journal of Virology
https://www.readbyqxmd.com/read/28423326/rapid-molecular-profiling-of-defined-cell-types-using-viral-trap
#11
Alexander R Nectow, Maria V Moya, Mats I Ekstrand, Awni Mousa, Kelly L McGuire, Caroline E Sferrazza, Bianca C Field, Gabrielle S Rabinowitz, Kirsty Sawicka, Yupu Liang, Jeffrey M Friedman, Nathaniel Heintz, Eric F Schmidt
Translational profiling methodologies enable the systematic characterization of cell types in complex tissues, such as the mammalian brain, where neuronal isolation is exceptionally difficult. Here, we report a versatile strategy for profiling CNS cell types in a spatiotemporally restricted fashion by engineering a Cre-dependent adeno-associated virus expressing an EGFP-tagged ribosomal protein (AAV-FLEX-EGFPL10a) to access translating mRNAs by translating ribosome affinity purification (TRAP). We demonstrate the utility of this AAV to target a variety of genetically and anatomically defined neural populations expressing Cre recombinase and illustrate the ability of this viral TRAP (vTRAP) approach to recapitulate the molecular profiles obtained by bacTRAP in corticothalamic neurons across multiple serotypes...
April 18, 2017: Cell Reports
https://www.readbyqxmd.com/read/28422057/antifungal-and-anti-biofilm-activities-of-acetone-lichen-extracts-against-candida-albicans
#12
Marion Millot, Marion Girardot, Lucile Dutreix, Lengo Mambu, Christine Imbert
Candida albicans is a commensal coloniser of the human gastrointestinal tract and an opportunistic pathogen, especially thanks to its capacity to form biofilms. This lifestyle is frequently involved in infections and increases the yeast resistance to antimicrobials and immune defenses. In this context, 38 lichen acetone extracts have been prepared and evaluated for their activity against C. albicans planktonic and sessile cells. Minimum inhibitory concentrations of extracts (MICs) were determined using the broth microdilution method...
April 19, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28421524/distance-dependent-varieties-of-microbial-community-structure-and-metabolic-functions-in-the-rhizosphere-of-sedum-alfredii-hance-during-phytoextraction-of-a-cadmium-contaminated-soil
#13
Wenhao Yang, Taoxiang Zhang, Sen Lin, Wuzhong Ni
The recovery of microbial community and activities is crucial to the remediation of contaminated soils. Distance-dependent variations of microbial community composition and metabolic characteristics in the rhizospheric soil of hyperaccumulator during phytoextraction are poorly understood. A 12-month phytoextraction experiment with Sedum alfredii in a Cd-contaminated soil was conducted. A pre-stratified rhizobox was used for separating sub-layer rhizospheric (0-2, 2-4, 4-6, 6-8, 8-10 mm from the root mat)/bulk soils...
April 18, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28419836/enzymatic-behavior-of-laccase-following-interaction-with-%C3%AE-cd-and-immobilization-into-pcl-nanofibers
#14
M Fatih Canbolat, Hasan Basri Savas, Fatih Gultekin
This study examines the effects of CD use on enzymatic activity, following enzyme immobilization into nanofibers. There is almost no research available on the change in enzyme activity following interaction with cyclodextrin and electrospun nanofiber mats together. Laccase enzyme was immobilized into nanofibrous structures by various techniques, with and without γ-CD addition, and the enzymatic activity of the laccase was analyzed. SEM, XRD, and FTIR analyses were used for the characterization of the resulting structures...
April 15, 2017: Analytical Biochemistry
https://www.readbyqxmd.com/read/28419436/ammonia-oxidizer-populations-vary-with-nitrogen-cycling-across-a-tropical-montane-mean-annual-temperature-gradient
#15
S Pierre, I Hewson, J P Sparks, C M Litton, C Giardina, P M Groffman, T J Fahey
Functional gene approaches have been used to better understand the roles of microbes in driving forest soil nitrogen (N) cycling rates and bioavailability. Ammonia oxidation is a rate limiting step in nitrification, and is a key area for understanding environmental constraints on N availability in forests. We studied how increasing temperature affects the role of ammonia oxidizing archaea (AOA) and bacteria (AOB) in soil N cycling and availability by using a highly constrained natural mean annual temperature (MAT) elevation gradient in a tropical montane wet forest...
April 18, 2017: Ecology
https://www.readbyqxmd.com/read/28418841/circulating-uric-acid-levels-and-subsequent-development-of-cancer-in-493-281-individuals-findings-from-the-amoris-study
#16
Andrew Yiu, Mieke Van Hemelrijck, Hans Garmo, Lars Holmberg, Håkan Malmström, Mats Lambe, Niklas Hammar, Göran Walldius, Ingmar Jungner, Wahyu Wulaningsih
OBJECTIVES: Serum uric acid has been suggested to be associated with cancer risk. We aimed to study the association between serum uric acid and cancer incidence in a large Swedish cohort. RESULTS: A positive association was found between uric acid levels and overall cancer risk, and results were similar with adjustment for glucose, triglycerides and BMI. Hazard ratio (HR) for overall cancer for the 4th quartile of uric acid compared to the 1st was 1.08 (95% CI: 1...
March 15, 2017: Oncotarget
https://www.readbyqxmd.com/read/28418209/acupressure-as-adjuvant-treatment-for-the-inpatient-management-of-nausea-and-vomiting-in-early-pregnancy-a-double-blind-randomized-controlled-trial
#17
Aizura-Syafinaz Adlan, Kar Yoke Chooi, Noor Azmi Mat Adenan
AIM: To evaluate the efficacy of acupressure at the Neiguan point (Pericardium [P]6) as adjuvant treatment during inpatient management of severe nausea and vomiting in pregnancy. METHODS: Low risk, spontaneously conceived singleton pregnancies were randomly assigned to a treatment group, who received an acupressure band placed at the Neiguan point (P6) or a placebo group who received an otherwise identical non-stimulating wristband. Participants wore the band for 12 h daily for the first three days of admission...
April 2017: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/28415793/clinical-framework-for-next-generation-sequencing-based-analysis-of-treatment-predictive-mutations-and-multiplexed-gene-fusion-detection-in-non-small-cell-lung-cancer
#18
Kajsa Ericson Lindquist, Anna Karlsson, Per Levéen, Hans Brunnström, Christel Reuterswärd, Karolina Holm, Mats Jönsson, Karin Annersten, Frida Rosengren, Karin Jirström, Jaroslaw Kosieradzki, Lars Ek, Åke Borg, Maria Planck, Göran Jönsson, Johan Staaf
Precision medicine requires accurate multi-gene clinical diagnostics. We describe the implementation of an Illumina TruSight Tumor (TST) clinical NGS diagnostic framework and parallel validation of a NanoString RNA-based ALK, RET, and ROS1 gene fusion assay for combined analysis of treatment predictive alterations in non-small cell lung cancer (NSCLC) in a regional healthcare region of Sweden (Scandinavia). The TST panel was clinically validated in 81 tumors (99% hotspot mutation concordance), after which 533 consecutive NSCLCs were collected during one-year of routine clinical analysis in the healthcare region (~90% advanced stage patients)...
March 16, 2017: Oncotarget
https://www.readbyqxmd.com/read/28415483/an-investigation-of-electrospun-henna-leaves-extract-loaded-chitosan-based-nanofibrous-mats-for-skin-tissue-engineering
#19
Iman Yousefi, Mehdi Pakravan, Hoda Rahimi, Abbas Bahador, Zahra Farshadzadeh, Ismael Haririan
Wound healing characteristics of some plant extracts have been well known for many years, and they have been utilized for such applications in traditional way. Recently electrospun nanofibrous mats showed promising properties for tissue engineering and especially for skin repair. It is expected that incorporation of plant extracts into such structures could provide higher performance and synergistic effect for biomedical and wound healing applications. The final purpose of this study is to fabricate chitosan based nanofiber mats loaded with a traditional plant extract of Lawsonia inermis (Henna) leaves to enhance the antibacterial efficacy and wound healing of the precursor nanofibers...
June 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28415467/poly-l-lactic-acid-and-polyurethane-nanofibers-fabricated-by-solution-blow-spinning-as-potential-substrates-for-cardiac-cell-culture
#20
Ewelina Tomecka, Michal Wojasinski, Elzbieta Jastrzebska, Michal Chudy, Tomasz Ciach, Zbigniew Brzozka
This paper presents a comparison and evaluation of cardiac cell proliferation on poly(l-lactic acid) (PLLA) and polyurethane (PU) nanofibrous mats fabricated by solution blow spinning (SBS). Three different cardiac cell lines: rat cardiomyoblasts (H9C2 line), human (HCM) and rat cardiomyocytes (RCM) were used for experiments. Cell morphology, orientation and proliferation were investigated on non-modified and protein-modified (fibronectin, collagen, gelatin, laminin, poly-l-lysine) surfaces of both types of nanofibers...
June 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
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