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Saphenous vein

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https://www.readbyqxmd.com/read/29136654/vascular-surgical-stretch-injury-leads-to-activation-of-p2x7-receptors-and-impaired-endothelial-function
#1
Padmini Komalavilas, Weifeng Luo, Christy M Guth, Olukemi Jolayemi, Rachel I Bartelson, Joyce Cheung-Flynn, Colleen M Brophy
A viable vascular endothelial layer prevents vasomotor dysfunction, thrombosis, inflammation, and intimal hyperplasia. Injury to the endothelium occurs during harvest and "back table" preparation of human saphenous vein prior to implantation as an arterial bypass conduit. A subfailure overstretch model of rat aorta was used to show that subfailure stretch injury of vascular tissue leads to impaired endothelial-dependent relaxation. Stretch-induced impaired relaxation was mitigated by treatment with purinergic P2X7 receptor (P2X7R) inhibitors, brilliant blue FCF (FCF) and A740003, or apyrase, an enzyme that catalyzes the hydrolysis of ATP...
2017: PloS One
https://www.readbyqxmd.com/read/29126818/composite-y-grafts-from-the-left-internal-mammary-artery-current-considerations
#2
EDITORIAL
Hugh S Paterson, Paul G Bannon
The use of composite coronary artery bypass grafts from the left internal mammary artery (LIMA) has increased over the last 20 years. Total arterial revascularisation can be achieved with two arterial conduits and is associated with a reduced risk of stroke. However, the traditional coronary bypass graft configurations of the in situ LIMA and aorto-coronary saphenous vein grafts remain as the mainstay of coronary bypass surgery in most centres. Concerns regarding composite Y grafts relate to (1) the adequacy of a single inflow for all coronary bypass grafts; (2) the risk of compromising the LIMA flow to the left anterior descending coronary artery; (3) the effects of competitive flow on graft patency; and (4) the use of sequential coronary anastomoses...
October 28, 2017: Heart, Lung & Circulation
https://www.readbyqxmd.com/read/29122958/a-comparison-of-postoperative-morphometric-and-hemodynamic-changes-between-saphenous-vein-and-left-internal-mammary-artery-grafts
#3
Tingting Fan, Yundi Feng, Feng Feng, Zhongjie Yin, Dayou Luo, Yuan Lu, Yingjin Xu, Wenchang Tan, Yunlong Huo
There is higher long-term failure of the saphenous vein graft (SVG) compared with the left internal mammary artery (LIMA) graft, which is affected by the hemodynamic environment. A comprehensive analysis of postoperative structure-function changes is important to study the atherogenesis in the SVG A comparison of morphometric and hemodynamic parameters was carried out between LIMA grafts and SVGs and between different time points postoperatively. Various parameters were obtained from the image reconstruction and flow simulation in patients, who underwent CT exams for ~1 year, 5 and 10 years after revascularization...
November 2017: Physiological Reports
https://www.readbyqxmd.com/read/29121842/superior-mesenteric-vein-injury-during-oncologic-right-colectomy-current-vascular-repair-modalities
#4
Michael R Freund, Ilya Goldin, Petachia Reissman
PURPOSE: To review the different vascular repair options of superior mesenteric vein (SMV) damage during oncologic right colectomy. METHODS: This is a retrospective chart review of 5 cases in which severe damage to the SMV occurred during oncological right colectomy in an academic medical center. RESULTS: During a 10-year study period, we encountered 5 cases in which severe damage to the SMV and its tributaries occurred. Two of the patients underwent primary venous repair for partial lacerations...
January 1, 2017: Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/29117787/reprogramming-of-adult-peripheral-blood-cells-into-human-induced-pluripotent-stem-cells-as-a-safe-and-accessible-source-of-endothelial-cells
#5
Pavel Simara, Lenka Tesarova, Daniela Rehakova, Simon Farkas, Barbara Salingova, Katerina Kutalkova, Eva Vavreckova, Pavel Matula, Petr Matula, Lenka Veverkova, Irena Koutna
New approaches in regenerative medicine and vasculogenesis have generated a demand for sufficient numbers of human endothelial cells (ECs). ECs and their progenitors (EPCs) reside on the interior surface of blood and lymphatic vessels or circulate in peripheral blood; however, their numbers are limited and they are difficult to expand after isolation. Recent advances in human induced pluripotent stem cell (hiPSC) research have opened possible avenues to generate unlimited numbers of ECs from easily accessible cell sources, such as the peripheral blood...
November 8, 2017: Stem Cells and Development
https://www.readbyqxmd.com/read/29115044/a-leg-ulcer-with-pulsating-varicose-veins%C3%A2-%C3%A2-from-the-legs-to-the-heart
#6
Sabrina Johanna Swoboda, Hauke Schumann, Dimitra Kiritsi
We present the case of a 58-year-old man who presented to our wound care centre with a 7 -month history of a progressive unilateral leg ulcer. He reported intermittent, heavy bleeding at the ulcer. The duplex sonography showed a bilateral incompetence of the saphenofemoral junctions and the entire course of the great saphenous veins and, surprisingly, also a bilateral reversed arterial-like pulsating flow in the great and small saphenous veins as well as in the deep veins of the lower extremities. During cardiac examination by auscultation and echocardiography, we detected a previously undescribed severe tricuspid insufficiency with strongly reduced systolic ejection of both the left and the right ventricle and repercussions on the peripheral venous system as a cause for the pulsating veins...
November 7, 2017: International Wound Journal
https://www.readbyqxmd.com/read/29105677/-saphenous-vein-graft-aneurysm-percutaneous-exclusion-using-detachable-coils
#7
Roberto Spoladore, Andrea Fisicaro, Matteo Montorfano, Pietro Spagnolo, Antonio Colombo, Alberto Margonato
We report the case of a 78-year-old man admitted to the emergency department for typical angina onset with evidence of a large aneurysm of the coronary artery venous bypass graft, successfully closed using a percutaneous approach.
November 2017: Giornale Italiano di Cardiologia
https://www.readbyqxmd.com/read/29102747/endoscopic-versus-open-great-saphenous-vein-harvesting-for-femoral-to-popliteal-artery-bypass
#8
Aleem K Mirza, Kendall Stauffer, Mark D Fleming, Randall De Martino, Gustavo Oderich, Manju Kalra, Peter Gloviczki, Thomas Bower
OBJECTIVE: Conflicting data exist on outcomes of open vein harvest (OVH) and endoscopic vein harvest (EVH) for infrainguinal bypass. The purpose of this study was to compare outcomes between OVH and EVH in femoral to popliteal artery bypasses. METHODS: A retrospective review was performed of all patients undergoing common femoral to popliteal artery bypass with great saphenous vein between January 1997 and June 2014. Bypasses using arm or composite vein were excluded, as were those performed for popliteal artery aneurysms or trauma...
November 1, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/29098093/epoetin-alfa-a-cause-of-coronary-artery-thrombosis
#9
Muhammad Umer Siddiqui, Yelena Galumyan, James Klein, Zunaira Naeem, Aron Schwarcz
Introduction: Epoetin alfa is an erythrocyte-stimulating factor. We here present a case of an anemic patient, who was given epogen before a coronary artery bypass (CABG) surgery and developed periprocedural myocardial infarction. To our knowledge, there has been no previous case reported of epogen causing myocardial infarction. Case Presentation: 66-year-old female presented with substernal chest pain. EKG showed ST segment elevations in aVf and L-III. Patient underwent left heart catheterization (LHC) and had triple vessel disease...
2017: Case Reports in Cardiology
https://www.readbyqxmd.com/read/29097174/medical-management-of-acute-superficial-vein-thrombosis-of-the-saphenous-vein
#10
REVIEW
Sherry D Scovell, Emel A Ergul, Mark F Conrad
OBJECTIVE: Acute superficial vein thrombosis (SVT) of the axial veins, such as the great saphenous vein (GSV), is a common clinical condition that carries with it significant risk of propagation of thrombus, recurrence, and, most concerning, subsequent venous thromboembolism (VTE). Conservative therapy with nonsteroidal anti-inflammatory medication and heat does not prevent extension of thrombus or protect against recurrent or future VTE in patients with extensive SVT (thrombotic segment of at least 5 cm in length)...
October 30, 2017: Journal of Vascular Surgery. Venous and Lymphatic Disorders
https://www.readbyqxmd.com/read/29097173/effect-of-tumescent-anesthesia-and-patient-positioning-on-laser-tip-junctional-distance-during-endovenous-laser-ablation
#11
Julien Al Shakarchi, Mark Kay, Smilen Kuyumdzhiev, Vasileios Psarros, Radu Rogoveanu, Rajiv Vohra
BACKGROUND: The correct positioning of the laser tip at the saphenofemoral or saphenopopliteal junction during endovenous laser therapy is paramount to ensure a safe and effective procedure. The aim of this study was to demonstrate how patient positioning and tumescence infiltration can affect this safe junctional distance. METHODS: A retrospective review of a prospectively maintained database was carried out for all patients who received endovenous laser treatment for symptomatic varicose veins between February 2008 and February 2014 in one surgeon's practice in a teaching hospital vascular unit...
October 30, 2017: Journal of Vascular Surgery. Venous and Lymphatic Disorders
https://www.readbyqxmd.com/read/29096125/biaxial-mechanical-behavior-of-bovine-saphenous-venous-valve-leaflets
#12
Jiaqi Lu, Hsiao-Ying Shadow Huang
Chronic venous disease is caused by chronic venous insufficiency (CVI), which results in significant symptoms such as venous ulcers, ankle eczema, leg swelling, etc. Venous valve incompetence is a major cause of CVI. When the valves of veins in the leg become incompetent (i.e., do not close properly), blood is able to flow backwards (i.e., reflux), which results in blood pooling in the lower extremities, distal venous hypertension, and CVI. Current clinical therapies, such as surgical venous valve reconstruction and bioprosthetic venous valve replacement, are highly invasive and only moderately successful...
October 24, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/29094390/reconstruction-of-a-long-defect-of-the-ulnar-artery-and-nerve-with-an-arterialized-neurovenous-free-flap-in-a-teenager-a-case-report-and-literature-review
#13
Diogo Casal, Diogo Pais, Eduarda Mota-Silva, Giovanni Pelliccia, Inês Iria, Paula A Videira, Maria Manuel Mendes, João Goyri-O'Neill, Maria Manuel Mouzinho
There is evidence that nerve flaps are superior to nerve grafts for bridging long nerve defects. Moreover, arterialized neurovenous flaps (ANVFs) have multiple potential advantages over traditional nerve flaps in this context. This paper describes a case of reconstruction of a long defect of the ulnar artery and nerve with an arterialized neurovenous free flap and presents a literature review on this subject. A 16-year-old boy sustained a stab wound injury to the medial aspect of the distal third of his right forearm...
November 2, 2017: Microsurgery
https://www.readbyqxmd.com/read/29089972/a-huge-thrombosed-aneurysm-of-a-saphenous-vein-graft-leading-to-compression-of-cardiac-structures-role-of-multimodality-imaging
#14
Byung Gyu Kim, In-Cheol Kim, Seok-Min Kang, Young-Nam Youn
No abstract text is available yet for this article.
August 2017: Journal of Geriatric Cardiology: JGC
https://www.readbyqxmd.com/read/29079734/limiting-injury-during-saphenous-vein-graft-preparation-for-coronary-arterial-bypass-prevents-metabolic-decompensation
#15
Joyce Cheung-Flynn, Jun Song, Igor Voskresensky, Eric S Wise, Yapu Liu, Yanhua Xiong, Susan S Eagle, Colleen M Brophy, C Robb Flynn
Standard harvest and preparation of human saphenous vein (HSV) for autologous coronary and peripheral arterial bypass procedures is associated with injury and increased oxidative stress that negatively affect graft performance. In this study we investigated the global metabolomic profiles of HSV before (unprepared; UP) and after standard vein graft preparation (AP). AP-HSV showed impaired vasomotor function that was associated with increased oxidative stress, phospholipid hydrolysis and energy depletion that are characteristic of mechanical and chemical injury...
October 27, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29071157/looking-beyond-oral-mucosa-initial-results-of-everted-saphenous-vein-graft-urethroplasty-esvgu-in-long-anterior-urethral-strictures
#16
Arif Akhtar, Nikhil Khattar, Hemant Goel, Swatantra Rao, Raman Tanwar, Rajeev Sood
OBJECTIVE: To prospectively evaluate the feasibility and initial results of an everted saphenous vein graft (eSVG) as a dorsolateral onlay, in patients with long anterior urethral strictures and/or chronic tobacco users. PATIENTS AND METHODS: In all, 20 patients with long anterior urethral strictures (>7 cm) and/or chronic tobacco exposed oral mucosa were included in the study. The harvested SVG was hydro-distended, detubularised, and everted. Substitution urethroplasty using an eSVG was performed using a dorsolateral onlay technique...
September 2017: Arab Journal of Urology
https://www.readbyqxmd.com/read/29068077/leiomyosarcoma-of-the-great-saphenous-vein-vena-saphena-magna-with-granular-cell-change-report-of-a-superficial-neoplasm
#17
Ricardo S Macarenco, Renee Zon Filippi, Felipe D'Almeida Costa, Reynaldo Jesus-Garcia
The great saphenous vein (GSV) corresponds to the main superficial large caliber vessel affected by leiomyosarcoma (LMS). Given its superficial location and because signs of vascular origin may not be clinically apparent, LMS of the GSV may be misinterpreted clinically as superficial non-vascular soft tissue mass. Herein we report a case on the distal portion of the right GSV of a 57year-old man. The histopathological recognition of a large caliber vein-associated LMS (with granular cell change) in an incisional biopsy specimen was crucial to guide radiological evaluation and confirmation of a superficial vascular LMS before surgical treatment...
October 25, 2017: Journal of Cutaneous Pathology
https://www.readbyqxmd.com/read/29064925/lower-extremity-free-flaps-for-breast-reconstruction
#18
REVIEW
Joseph H Dayan, Robert J Allen
Thigh-based flaps are typically a secondary option for breast reconstruction because of concerns regarding limited tissue volume and donor-site morbidity. In recent years, there have been a number of new techniques and insights that have resulted in greater flexibility and improved outcomes. This article reviews lessons learned from a large collective experience using the following 4 flaps: transverse upper gracilis also known as transverse myocutaneous gracilis, diagonal upper gracilis, profunda artery perforator, and lateral thigh perforator flaps...
November 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/29059371/randomized-comparison-of-the-clinical-outcome-of-single-versus-multiple-arterial-grafts-the-roma-trial-rationale-and-study-protocol
#19
Mario Gaudino, John H Alexander, Faisal G Bakaeen, Karla Ballman, Fabio Barili, Antonio Maria Calafiore, Piroze Davierwala, Steven Goldman, Peter Kappetein, Roberto Lorusso, Darren Mylotte, Domenico Pagano, Marc Ruel, Thomas Schwann, Hisayoshi Suma, David P Taggart, Robert F Tranbaugh, Stephen Fremes
The primary hypothesis of the ROMA trial is that in patients undergoing primary isolated non-emergent coronary artery bypass grafting, the use of 2 or more arterial grafts compared with a single arterial graft (SAG) is associated with a reduction in the composite outcome of death from any cause, any stroke, post-discharge myocardial infarction and/or repeat revascularization. The secondary hypothesis is that in these patients, the use of 2 or more arterial grafts compared with a SAG is associated with improved survival...
October 20, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/29049458/long-term-outcomes-of-multiple-arterial-coronary-artery-bypass-grafting-a-population-based-study-of-patients-in-british-columbia-canada
#20
Aihua Pu, Lillian Ding, Jungwon Shin, Joel Price, Peter Skarsgard, Daniel R Wong, John Bozinovski, Guy Fradet, James G Abel
Importance: Although the long-term survival advantage of multiple arterial grafting (MAG) vs the standard use of left internal thoracic artery (LITA) supplemented by saphenous vein grafts (LITA+SVG) has been demonstrated in several observational studies, to our knowledge its safety and other long-term clinical benefits in a large, population-based cohort are unknown. Objective: To compare the safety and long-term outcomes of MAG vs LITA+SVG among overall and selected subgroups of patients...
November 1, 2017: JAMA Cardiology
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