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Smadar Valérie Tourjman, Robert-Paul Juster, Scot Purdon, Emmanuel Stip, Edouard Kouassi, Stéphane Potvin
OBJECTIVE: To assess the relationship between the Screen for Cognitive Impairment in Psychiatry (SCIP) score and illness severity, subjective cognition and functioning in a cohort of major depressive disorder (MDD) patients. METHODS: Patients (n = 40) diagnosed with MDD (DSM-IV-TR) completed the SCIP, a brief neuropsychological test, and a battery of self-administered questionnaires evaluating functioning (GAF, SDS, WHODAS 2.0, EDEC, PDQ-D5). Disease severity was evaluated with the Hamilton Depression Rating Scale (HDRS) and the Clinical Global Impression (CGI)...
March 19, 2018: International Journal of Psychiatry in Clinical Practice
Mario Latendresse, Peter D Karp
BACKGROUND: Completion of genome-scale flux-balance models using computational reaction gap-filling is a widely used approach, but its accuracy is not well known. RESULTS: We report on computational experiments of reaction gap filling in which we generated degraded versions of the EcoCyc-20.0-GEM model by randomly removing flux-carrying reactions from a growing model. We gap-filled the degraded models and compared the resulting gap-filled models with the original model...
February 14, 2018: BMC Bioinformatics
Dirk Spann, Eva Pross, Yuanyuan Chen, Ross E Dalbey, Andreas Kuhn
The membrane insertase YidC catalyzes the entrance of newly synthesized proteins into the lipid bilayer. As an integral membrane protein itself, YidC can be found as a monomer, a dimer or also as a member of the holotranslocase SecYEGDF-YajC-YidC. To investigate whether the dimeric YidC is functional and whether two copies cooperate to insert a single substrate, we constructed a fusion protein where two copies of YidC are connected by a short linker peptide. The 120 kDa protein is stable and functional as it supports the membrane insertion of the M13 procoat protein, the C-tailed protein SciP and the fusion protein Pf3-Lep...
January 12, 2018: Scientific Reports
M Sanchez-Autet, B Arranz, G Safont, P Sierra, A Garcia-Blanco, L de la Fuente, M Garriga, M P García-Portilla
BACKGROUND: Cognitive and psychosocial impairment has been associated with increased levels of C-reactive protein (CRP) and homocysteine in bipolar disorder, but gender differences have seldom been studied. METHODS: Two hundred and twenty-four bipolar outpatients were included. Cognitive performance was assessed through the Screen for Cognitive Impairment in Psychiatry (SCIP). Psychosocial functioning was evaluated using the Functioning Assessment Short Test (FAST) and the General Assessment of Functioning (GAF)...
December 27, 2017: Journal of Affective Disorders
Hyunju Yang, Alexa Watach, Miranda Varrasse, Tonya S King, Amy M Sawyer
STUDY OBJECTIVES: Determine the Multivariable Apnea Prediction (MAP) index predictive utility for enrollment enrichment in a clinical trial wherein enrollment was prior to obstructive sleep apnea diagnosis. METHODS: Secondary analysis of screening data (n = 264) from randomized, double-blind, pilot trial. Clinical sleep center patients with complete screening and polysomnography data were included. To determine diagnostic test accuracy of the MAP index using apnea-hypopnea index criterion ≥ 10 events/h (primary) and ≥ 5, ≥ 15, and ≥ 30 events/h (secondary), sensitivity, specificity, negative and positive predictive values, likelihood positive and negative ratios, and receiver operating characteristic curves were calculated...
December 13, 2017: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
Miklos D Kertai, Mary Cooter, Richard J Pollard, William Buhrman, Solomon Aronson, Joseph P Mathew, Mark Stafford-Smith
BACKGROUND: While continuation of β-blockers (BBs) perioperatively has become a national quality improvement measure, the relationship between BB withdrawal and mortality and cardiovascular-related critical quality indicators has not been studied in a contemporary cohort of patients undergoing noncardiac surgery. METHODS: For this retrospective study, the quality assurance database of a large community-based anesthesiology group practice was used to identify 410,288 surgical cases, 18 years of age or older, who underwent elective or emergent noncardiac surgical procedures between January 1, 2009, and December 31, 2014...
November 30, 2017: Anesthesia and Analgesia
Kyeong-Tae Lee, Bo Young Park, Eun-Ji Kim, Jung-Han Kim, Kee-Taek Jang, Sang-Hee Choi, Dong-Youn Lee, Goo-Hyun Mun
BACKGROUND: This study aimed to use a superthin, free superficial circumflex iliac artery perforator (SCIP) flap in functional surgery for treating subungual melanoma and to evaluate its outcomes. METHODS: Forty-one patients with primary subungual melanoma of less than or equal to 2-mm thickness who were treated with functional surgery were prospectively enrolled. After oncologic resection, a thin SCIP flap was harvested along the trans-superficial fat layer and transferred to the defect with further thinning by primary defatting...
December 2017: Plastic and Reconstructive Surgery
Ang Zeng, Kexin Song, Mingzi Zhang, Quancang Men, Youbin Wang, Lin Zhu, Zhifei Liu
BACKGROUND: Keloid therapy remains a great challenge for plastic surgeons, especially when the defect cannot be closed primarily, necessitating tissue transplantation. Here, we introduce a new treatment modality, called the sandwich therapy, for presternal keloids; the sandwich therapy incorporates preradiotherapy, superficial circumflex iliac artery perforator (SCIP) flap transplantation, and postradiotherapy. METHODS: From December 2012 to October 2013, 12 patients received the "sandwich therapy...
September 2017: Annals of Plastic Surgery
M J Byrne, S N Rogers
The amount of information wanted by patients after the diagnosis of cancer of the head and neck varies, and valid consent is not possible without information. The Patients' Concerns Inventory (diagnosis) (PCI-D) is a list intended to prompt patients to ask about aspects of their diagnosis and its potential treatments and outcomes. It has not previously been evaluated in clinical practice. Our aim was to assess how often patients recall using it and their satisfaction with both it and the information they received...
July 3, 2017: British Journal of Oral & Maxillofacial Surgery
Jacqueline Gaile, Catherine Adams
BACKGROUND: Metacognition is a significant component of complex interventions for children who have developmental language disorders. Research into how metacognition operates in the content or process of developmental language therapy delivery is limited. Identification and description of proposed active therapy components, such as metacognition, may contribute to our understanding of how to deliver complex communication interventions in an optimal manner. AIMS: To analyse aspects of metacognition during therapy derived from a manualized speech and language intervention (the Social Communication Intervention Programme-SCIP) as delivered to children who have social (pragmatic) communication disorder (SPCD) and to examine the dynamic process of delivering therapy...
June 16, 2017: International Journal of Language & Communication Disorders
Victor Chang, Robert H Blackwell, Talar Markossian, Ryan M Yau, Barbara A Blanco, Matthew A C Zapf, Gerard J Abood, Gopal N Gupta, Paul C Kuo, Anai N Kothari
BACKGROUND: Infectious (INF) and venous thromboembolism (VTE) complication rates are targeted by surgical care improvement project (SCIP) INF and SCIP VTE measures. We analyzed how adherence to SCIP INF and SCIP VTE affects targeted postoperative outcomes (wound complication [WC], deep vein thrombosis, and pulmonary embolism [PE]) using all-payer data. MATERIALS AND METHODS: A retrospective review (2007-2011) was conducted using Healthcare Cost and Utilization Project State Inpatient Database Florida and Medicare's Hospital Compare...
May 15, 2017: Journal of Surgical Research
Kensuke Tashiro, Shuji Yamashita
Reconstruction of dorsalis pedis with soft tissue is challenging because it needs to preserve thin structure to ensure that the patient will be able to wear shoes. Here, we report the use of a thin superficial circumflex iliac artery perforator (SCIP) flap in dorsalis pedis reconstruction. A 67-year-old man presented with a third-degree burn, which exposed his extensor tendons. A thin SCIP flap from the left inguinal region measuring 15 × 4 cm was transferred to the dorsalis pedis region. Postoperatively, no major cosmetic or functional problems were observed...
April 2017: Plastic and Reconstructive Surgery. Global Open
Hyunsuk Peter Suh, Min Young Jang, Joon Pio Jp Hong
No abstract text is available yet for this article.
July 2017: Plastic and Reconstructive Surgery
N Sidhoum, S Dast, S Perez, N Assaf, C Herlin, R Sinna
The SCIP flap based on a superficial circumflex iliac perforator artery (SCIA) was described for the first time by Koshima in 2004 as a large and thin groin flap, with a low morbidity. The purpose of this study is to demonstrate the benefits of SCIP flap to cover cutaneous defects. We present a retrospective study from January 2007 to August 2016. Twelve patients had a SCIP flap reconstruction in the plastic surgery department of Amiens hospital. Thirteen flaps were performed. The average preoperative doppler mapping time was 8minutes...
December 2017: Annales de Chirurgie Plastique et Esthétique
Jennifer A Kaplan, Jonathan T Carter
BACKGROUND: The Joint Commission's SCIP Inf-9 mandated early removal of indwelling urinary catheters (IUCs), but the impact of compliance on catheter-associated urinary tract infection (CAUTI) and postoperative urinary retention (POUR) are unknown. METHODS: Retrospective pre- and post-intervention study at a single tertiary academic medical center of all patients undergoing general surgery procedures with an IUC placed at the time of surgery who were admitted for at least two days before and after a Best Practice Advisory was put in place to improve compliance with SCIP Inf-9...
January 2018: American Journal of Surgery
Thomas B Bemenderfer, Nigel L Rozario, Charity G Moore, Madhav A Karunakar
BACKGROUND: Following evidence questioning the safety and efficacy of perioperative beta-blocker therapy in noncardiac surgery, the Surgical Care Improvement Project (SCIP) guidelines were retired in 2015. However, perioperative myocardial infarctions and cardiac complications remain leading causes of mortality following noncardiac surgery. The impact of the SCIP guidelines on reducing cardiac complications in patients undergoing elective total hip arthroplasty (THA) has not been evaluated...
August 2017: Journal of Arthroplasty
Yigit Kivilcim, Merih Altintas, Fusun Mayda Domac, Erkal Erzincan, Huseyin Gülec
PURPOSE: The aim of this study was to evaluate the prevalence of comorbid bipolar disorder (BD) among migraineurs and the impact of migraine-BD comorbidity on disease characteristics. PATIENTS AND METHODS: A total of 120 adult patients diagnosed with migraine at a single tertiary care center were included in this cross-sectional study. Data on sociodemographic and migraine-related characteristics, family history of psychiatric diseases, comorbid psychiatric diseases, and first-episode characteristics were recorded...
2017: Neuropsychiatric Disease and Treatment
James G Carlucci, Meridith Blevins Peratikos, Charlotte B Cherry, Melanie L Lopez, Ann F Green, Lazaro González-Calvo, Troy D Moon
BACKGROUND: Malaria is the leading cause of death among children in Mozambique. Prevalence and factors associated with malaria are not well studied among children in rural Zambézia Province. Whether prevalence of malaria varies across diverse districts within the province is unknown. METHODS: A cross-sectional survey of female heads of household was conducted during April and May 2014, a period of peak malaria transmission. Data were collected on up to two randomly selected children aged 6-59 months per household...
March 9, 2017: Malaria Journal
Christopher R Wolfe
This discussion of the symposium 20 Years of Internet-Based Research at SCiP: Surviving Concepts, New Methodologies compares the issues faced by the pioneering Internet-based psychology researchers who presented at the first symposia on the topic, at the 1996 annual meeting of the Society for Computers in Psychology, to the issues facing researchers today. New methodologies unavailable in the early days of Web-based psychological research are discussed, with an emphasis on mobile computing with smartphones that is capitalizing on capabilities such as touch screens and gyro sensors...
October 2017: Behavior Research Methods
Yujin Myung, Sangjun Yim, Baek-Kyu Kim
BACKGROUND: Management and reconstruction of dorsal foot defects present various difficulties and challenges. The main purpose of this article is to discuss experiences of using superficial circumflex iliac perforator (SCIP) flap in various defects of the dorsal foot region. METHODS: From August 2012 to February 2015, a total of 13 patients - nine males and four females - received a reconstruction operation for dorsal foot defects using SCIP flaps (the SCIP group)...
February 2, 2017: Journal of Plastic Surgery and Hand Surgery
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