M Persico, A Aglitti, A Aghemo, M Rendina, A Lleo, A Ciancio, V Di Marco, P Lampertico, M R Brunetto, M Zuin, P Andreone, E Villa, G Troshina, V Calvaruso, E Degasperi, B Coco, A Giorgini, F Conti, A Di Leo, L Marzi, V Boccaccio, S Bollani, P Maisonneuve, S Bruno
BACKGROUND: The efficacy of direct-acting anti-viral (DAA) therapy in patients with a history of hepatocellular carcinoma (HCC) is unknown. AIM: We prospectively evaluated whether previously treated HCC affects DAA efficacy in a large real-life cohort of cirrhotic patients. METHODS: From January to December 2015 all consecutive HCV mono-infected patients with cirrhosis and/or history of HCC attending 10 Italian tertiary liver centres were enrolled...
June 2018: Alimentary Pharmacology & Therapeutics