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https://www.readbyqxmd.com/read/29209125/transmitted-cardiovascular-pulsations-on-high-resolution-esophageal-impedance-manometry-and-their-significance-in-dysphagia
#1
Naueen A Chaudhry, Kamran Zahid, Sara Keihanian, Yunfeng Dai, Qing Zhang
AIM: To investigate the behavior of pulsatile pressure zones (PPZ's) as noted on high resolution esophageal impedance manometry (HREIM), and determine their association with dysphagia. METHODS: Retrospective, single center case control design screening HREIM studies for cases (dysphagia) and controls (no dysphagia). Thoracic radiology studies were reviewed further in cases for (thoracic cardiovascular) thoracic cardiovascular (TCV) structures in esophageal proximity to compare with HREIM findings...
November 28, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/29187997/internode-morphometrics-and-allometry-of-tonkin-cane-pseudosasa-amabilis
#2
Liang Cheng, Cang Hui, Gadi V P Reddy, Yu-Long Ding, Pei-Jian Shi
Pseudosasa amabilis (McClure) (Poales: Gramineae) is a typical bamboo species naturally distributed in large area of south China and famous for its culm strength. Although bamboos were found to share the same development rule, the detailed internode morphology of bamboo culm was actually not fully expressed. We explored internode morphology of P. amabilis using 11 different physical parameters in different dimensions (1-4). As Taylor's power law (TPL) is generally applicable to describe relationship between mean and variance of population density, here we used TPL to evaluate the differences between internodes, and further, the relationship between dimension and TPL...
November 2017: Ecology and Evolution
https://www.readbyqxmd.com/read/29161488/identifying-trypanosoma-cruzi-discreet-typing-units-in-triatomines-collected-in-different-natural-regions-of-per%C3%A3%C2%BA
#3
Carlos P Padilla, Uriel Alvarado, Gladis Ventura, Deysi Luna-Caipo, Marcial Suárez, José R Tuñoque, Nancy Ruelas-Llerena, Luis A Fachín, Alina Huiza, Lizandro Gonzáles, Julio César Carranza, Gustavo Adolfo Vallejo, Gustavo Adolfo Vallejo, Abraham G Cáceres, Abraham G Cáceres
INTRODUCTION: Trypanosoma cruzi has been divided by international consensus into six discrete typing units (DTU): TcI, TcII, TcIII, TcIV, TcV y TcVI. The factors determining the dynamics of T. cruzi genotypes vector transmission of Chagas' disease in the different geographical regions of Perú are still unknown. OBJECTIVE: To detect and type T. cruzi DTUs from the faeces of seven species of triatomines (Panstrongylus chinai, P. geniculatus, P. herreri, Rhodnius robustus, R...
March 29, 2017: Biomédica: Revista del Instituto Nacional de Salud
https://www.readbyqxmd.com/read/29158933/squamous-cell-carcinoma-of-the-thyroid-as-a-result-of-anaplastic-transformation-from-braf-positive-papillary-thyroid-cancer
#4
Alina Basnet, Aakriti Pandita, Joseph Fullmer, Abirami Sivapiragasam
Papillary thyroid carcinoma (PTC) is the most common malignant neoplasm of the thyroid. Majority of the PTC carries an excellent prognosis. However, patients with tall cell variant (TCV) of papillary thyroid carcinoma have a worse prognosis than those with the classic variant. On the other hand, squamous cell carcinoma of the thyroid (SCT) is an unusual neoplasm thought to arise as a primary tumor or as a component of an anaplastic or undifferentiated carcinoma. We report a patient with TCV of PTC presenting years later with squamous transformation...
2017: Case Reports in Oncological Medicine
https://www.readbyqxmd.com/read/29046868/inactive-trans-sialidase-expression-in-its-null-trypanosoma-cruzi-generates-virulent-trypomastigotes
#5
Carla A Pascuale, Juan M Burgos, Miriam Postan, Andrés B Lantos, Adriano Bertelli, Oscar Campetella, M Susana Leguizamón
Disclosing virulence factors from pathogens is required to better understand the pathogenic mechanisms involved in their interaction with the host. In the case of Trypanosoma cruzi several molecules are associated with virulence. Among them, the trans-sialidase (TS) has arisen as one of particular relevance due to its effect on the immune system and involvement in the interaction/invasion of the host cells. The presence of conserved genes encoding for an inactive TS (iTS) isoform is puzzlingly restricted to the genome of parasites from the Discrete Typing Units TcII, TcV, and TcVI, which include highly virulent strains...
2017: Frontiers in Cellular and Infection Microbiology
https://www.readbyqxmd.com/read/29037251/cytochrome-c-oxidase-subunit-1-gene-as-a-dna-barcode-for-discriminating-trypanosoma-cruzi-dtus-and-closely-related-species
#6
Marina Silva Rodrigues, Karina Alessandra Morelli, Ana Maria Jansen
BACKGROUND: The DNA barcoding system using the cytochrome c oxidase subunit 1 mitochondrial gene (cox1 or COI) is highly efficient for discriminating vertebrate and invertebrate species. In the present study, we examined the suitability of cox1 as a marker for Trypanosoma cruzi identification from other closely related species. Additionally, we combined the sequences of cox1 and the nuclear gene glucose-6-phosphate isomerase (GPI) to evaluate the occurrence of mitochondrial introgression and the presence of hybrid genotypes...
October 16, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/29022644/assessment-of-risk-factors-in-metastatic-recurrent-tall-cell-variant-of-papillary-thyroid-carcinoma
#7
Kursat Okuyucu, Engin Alagoz, Semra Ince, Nuri Arslan
INTRODUCTION: Papillary thyroid carcinoma (PTC) is the most common malignant thyroid tumor. A great majority of the cases live a disease-free life with quite favorable prognosis. There are lots of variants of PTC and a few of them exhibit aggressive behaviour. Typical example is the tall cell variant (TCV). Patients experience a greater incidence of recurrence, nodal and extranodal metastases, tumor associated mortality than other variants of PTC. Studies related to TCV almost always compared it with its patient population of PTC according to risk factors and clinicopathologic features...
October 12, 2017: Endokrynologia Polska
https://www.readbyqxmd.com/read/29020884/pathologic-reporting-of-tall-cell-variant-of-papillary-thyroid-cancer-have-we-reached-a-consensus
#8
Juan C Hernandez-Prera, Rosalie A Machado, Sylvia L Asa, Zubair Baloch, William C Faquin, Ronald Ghossein, Virginia A LiVolsi, Ricardo V Lloyd, Ozgur Mete, Yuri E Nikiforov, Raja R Seethala, Saul Suster, Lester D Thompson, Andrew T Turk, Peter M Sadow, Mark L Urken, Bruce M Wenig
BACKGROUND: Tall-cell variant (TCV) is widely believed to be a more aggressive subtype of papillary thyroid carcinoma (PTC). Despite the significance of TCV with respect to risk stratification and therapeutic decision making, its diagnosis is subject to inter-observer variability. This study aimed to determine the level of agreement among expert pathologists in the identification and reporting of TCV. METHODS: Seventeen surgical resections for thyroid cancer containing the diagnostic term "tall cell" in their pathology reports and 22 cases diagnosed as classical PTC were selected...
November 7, 2017: Thyroid: Official Journal of the American Thyroid Association
https://www.readbyqxmd.com/read/28974230/effect-of-day-3-embryo-morphometrics-and-morphokinetics-on-survival-and-implantation-after-slow-freezing-thawing-and-after-vitrification-warming-a-retrospective-cohort-study
#9
Elia Fernandez Gallardo, Carl Spiessens, Thomas D'Hooghe, Sophie Debrock
BACKGROUND: Morphometric and morphokinetic evaluation of in vitro cultured human embryos allows evaluation without time restriction and reduces intra- and inter-observer variability. Even though these technologies have been reported to improve the quality of cleavage stage embryo evaluation during fresh culture, possible advantages in the evaluation of cryopreserved embryos have been scarcely explored. This study aims to compare morphometric and morphokinetic parameters between slow frozen and vitrified embryos and to determine their relationship to embryo survival and implantation rate (IR) after thawing/warming...
October 3, 2017: Reproductive Biology and Endocrinology: RB&E
https://www.readbyqxmd.com/read/28967039/heterogeneity-of-multimedia-exposures-to-neurotoxic-elements-al-as-cd-pb-mn-and-hg-in-breastfed-infants-from-porto-velho-brazil
#10
Wanderley R Bastos, Solange M Vieira, Ângelo G Manzatto, José G Dórea, Marcelo C Rubira, Victor Francisco P de Souza, Walkimar A da Costa Junior, Maria T Souza Bastos
Infant exposure to neurotoxic elements is a public health issue that needs monitoring with regard to breast milk composition. We studied six neurotoxic elements in breast milk samples at different stages of lactation in mothers from Porto Velho, Brazil. We used a flow-injection mercury system (FIMS) to determine total Hg concentrations and an inductively coupled plasma optical emission spectrometer (ICP-OES) to determine the concentrations of Al, As, Cd, Pb, and Mn in 106 donors of a human milk bank. Association rules analyses were applied to determine the pattern of binary and ternary mixtures of the measured exposants...
October 1, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/28954072/combined-parasitological-and-molecular-based-diagnostic-tools-improve-the-detection-of-trypanosoma-cruzi-in-single-peripheral-blood-samples-from-patients-with-chagas-disease
#11
Fabiana Caroline Zempulski Volpato, Giovane Rodrigo Sousa, Daniella Alchaar D'Ávila, Lúcia Maria da Cunha Galvão, Egler Chiari
INTRODUCTION: In order to detect Trypanosoma cruzi and determine the genetic profiles of the parasite during the chronic phase of Chagas disease (ChD), parasitological and molecular diagnostic methods were used to assess the blood of 91 patients without specific prior treatment. METHODS: Blood samples were collected from 68 patients with cardiac ChD and 23 patients with an indeterminate form of ChD, followed by evaluation using blood culture and polymerase chain reaction...
July 2017: Revista da Sociedade Brasileira de Medicina Tropical
https://www.readbyqxmd.com/read/28937826/choroidal-variations-in-diabetic-macular-edema-fluorescein-angiography-and-optical-coherence-tomography
#12
Xiangning Wang, Shuting Li, Wei Li, Yanjun Hua, Qiang Wu
PURPOSES: To (i) evaluate variations in choroidal thickness (CT) and choroidal volume (CV) in diabetic macular edema (DME), as demonstrated by fluorescein angiography (FA) and enhanced depth-imaging (EDI) optical coherence tomography (OCT) (EDI-OCT) and (ii) correlate these variations with visual acuity. METHODS: This study was a retrospective observational case series of patients with diabetic retinopathy (DR) and DME. The study groups comprised 77 DR patients (n = 87), all of whom underwent color fundus photography, FA, and OCT on the same day...
September 22, 2017: Current Eye Research
https://www.readbyqxmd.com/read/28863634/correlation-electron-cyclotron-emission-diagnostic-in-tcv
#13
M Fontana, L Porte, P Molina Cabrera
The correlation electron cyclotron emission diagnostic of tokamak à configuration variable has recently been upgraded. It now has the choice of three lines of sight: two horizontal lines placed on the low field side of the vessel, perpendicular to the magnetic field, and a dual-axis steerable antenna. The polarization of the radiation collected by the latter can be rotated using a universal polarizer situated in the transmission line. This line is also shared with a reflectometry system, allowing simultaneous measurements of temperature and density fluctuations in the same plasma volumes...
August 2017: Review of Scientific Instruments
https://www.readbyqxmd.com/read/28802757/the-typhoid-vaccine-acceleration-consortium-tyvac-vaccine-effectiveness-study-designs-accelerating-the-introduction-of-typhoid-conjugate-vaccines-and-reducing-the-global-burden-of-enteric-fever-report-from-a-meeting-held-on-26-27-october-2016-oxford-uk
#14
James E Meiring, Malick Gibani
Typhoid fever is estimated to cause between 11.9-26.9 million infections globally each year with 129,000-216,510 deaths. Access to improved water sources have reduced disease incidence in parts of the world but the use of efficacious vaccines is seen as an important public health tool for countries with a high disease burden. A new generation of Vi typhoid conjugate vaccines (TCVs), licensed for use in young children and expected to provide longer lasting protection than previous vaccines, are now available...
September 12, 2017: Vaccine
https://www.readbyqxmd.com/read/28697188/impact-of-tall-cell-variant-histology-on-predicting-relapse-and-changing-the-management-of-papillary-thyroid-carcinoma-patients
#15
Bengul Gunalp, Kursat Okuyucu, Semra Ince, Aslı Ayan, Engin Alagoz
OBJECTIVE: There has been much discussion recently about the risk category of tall cell variant (TVC) histology and its effects on the management of papillary thyroid carcinoma (PTC). We, therefore, undertook a retrospective study to compare stage-matched risk factors and recurrence rates between classical PTC (cPTC) patients and patients with TCV histology. SUBJECTS AND METHODS: A total of 3128 well-differentiated thyroid carcinoma patients who were treated and followed-up for more than 5 years in our clinic from 1995 to 2016 were included in this study...
May 2017: Hellenic Journal of Nuclear Medicine
https://www.readbyqxmd.com/read/28604164/a-forecast-of-typhoid-conjugate-vaccine-introduction-and-demand-in-typhoid-endemic-low-and-middle-income-countries-to-support-vaccine-introduction-policy-and-decisions
#16
Vittal Mogasale, Enusa Ramani, Il Yeon Park, Jung Seok Lee
A Typhoid Conjugate Vaccine (TCV) is expected to acquire WHO prequalification soon, which will pave the way for its use in many low- and middle-income countries where typhoid fever is endemic. Thus it is critical to forecast future vaccine demand to ensure supply meets demand, and to facilitate vaccine policy and introduction planning. We forecasted introduction dates for countries based on specific criteria and estimated vaccine demand by year for defined vaccination strategies in 2 scenarios: rapid vaccine introduction and slow vaccine introduction...
September 2, 2017: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/28597620/critical-velocity-in-swimmers-of-different-ages
#17
Alex Rizzato, Giuseppe Marcolin, Alessandro Rubini, Nicola Olivato, Simone Fava, Antonio Paoli, Gerardo Bosco
BACKGROUND: In swimming one of the most employed training speed among coaches is the non-invasive Theoretical Critical Velocity (TCV) defined as the velocity that can be maintained continuously without exhaustion. METHODS: We calculated the 4mmol/L lactate Critical Velocity (MCV) in a group of swimmers of different ages (Young, Elite and Master), and compared results to the predicted TCV defined starting from the 200 and 400 m freestyle best seasonal performances...
June 8, 2017: Journal of Sports Medicine and Physical Fitness
https://www.readbyqxmd.com/read/28529577/aggressiveness-of-the-tall-cell-variant-of-papillary-thyroid-carcinoma-is-independent-of-the-tumor-size-and-patient-age
#18
Rocío Villar-Taibo, Diego Peteiro-González, José Manuel Cabezas-Agrícola, Elvin Aliyev, Francisco Barreiro-Morandeira, Clara Ruiz-Ponte, José M Cameselle-Teijeiro
The tall cell variant (TCV) of papillary thyroid carcinoma (PTC) is characterized by tall columnar cells with a height of at least three times their width. TCV usually presents at an older age, has a larger size and exhibits more extrathyroidal extension and metastases than classical PTC. The current study compared TCV with the classical and follicular variants (CaFVs) of PTC to determine if, irrespective of the age at diagnosis and tumor size, TCV is more aggressive than its classical and follicular counterparts...
May 2017: Oncology Letters
https://www.readbyqxmd.com/read/28528434/tall-cell-and-diffuse-sclerosing-variants-of-papillary-thyroid-cancer-outcome-and-predicting-value-of-risk-stratification-methods
#19
M Russo, P Malandrino, M Moleti, F Vermiglio, M A Violi, I Marturano, E Minaldi, R Vigneri, G Pellegriti, C Regalbuto
PURPOSE: Tall cell (TCV) and diffuse sclerosing (DSV) variants are aggressive variants of papillary thyroid cancer (PTC). We compared the risk of recurrent/persistent disease in patients with TCV, DSV and classical PTC (cPTC) and evaluated the prognostic accuracy of initial vs. ongoing risk stratification. METHODS: A consecutive series of DSV (n = 54), TCV (n = 72) and cPTC (n = 184) patients was retrospectively analyzed. TCV and DSV patients were first risk stratified for recurrent/persistent disease without considering the histotype as a risk factor and subsequently, 6-24 months after initial treatment, re-classified on the basis of the response to therapy (ongoing risk stratification)...
November 2017: Journal of Endocrinological Investigation
https://www.readbyqxmd.com/read/28527687/cost-effectiveness-analysis-of-typhoid-conjugate-vaccines-in-five-endemic-low-and-middle-income-settings
#20
Marina Antillón, Joke Bilcke, A David Paltiel, Virginia E Pitzer
BACKGROUND: Typhoid fever remains endemic in low- and middle-income countries. Programmatic use of existing vaccines is limited, but upcoming typhoid conjugate vaccines (TCVs) could warrant wider use. We evaluated the cost-effectiveness of five TCV delivery strategies in three urban areas (Delhi and Kolkata, India and Nairobi, Kenya) and two rural settings (Lwak, Kenya and Dong Thap, Vietnam) with varying incidence. METHODS AND FINDINGS: We evaluated routine infant vaccination with and without catch-up campaigns among older individuals...
June 14, 2017: Vaccine
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