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https://www.readbyqxmd.com/read/29031081/optimization-of-the-promega-powerseq%C3%A2-auto-y-system-for-efficient-integration-within-a-forensic-dna-laboratory
#1
E A Montano, J M Bush, A M Garver, M M Larijani, S M Wiechman, C H Baker, M R Wilson, R A Guerrieri, E A Benzinger, D N Gehres, M L Dickens
The application of massively parallel sequencing (MPS) is growing in the forensic DNA field, as forensic DNA laboratories are continuously seeking methods to gain information from a limited or degraded forensic sample. However, the laborious nature of current MPS methodologies required for successful library preparation and sequencing leave opportunities for improvement to make MPS a practical option for processing forensic casework. In this study, the Promega PowerSeq™ Auto/Y System Prototype, a MPS laboratory workflow that incorporates multiplex amplification, was selected for optimization with the objectives to introduce automation for relieving manual processing, and to reduce the number of steps recommended by the standard protocol...
October 5, 2017: Forensic Science International. Genetics
https://www.readbyqxmd.com/read/29029352/patient-satisfaction-outcomes-after-robotic-arm-assisted-total-knee-arthroplasty-a-short-term-evaluation
#2
Robert C Marchand, Nipun Sodhi, Anton Khlopas, Assem A Sultan, Steven F Harwin, Arthur L Malkani, Michael A Mont
No abstract text is available yet for this article.
October 13, 2017: Journal of Knee Surgery
https://www.readbyqxmd.com/read/29029111/short-term-and-mid-term-survival-in-bronchial-sleeve-resection-by-robotic-system-versus-thoracotomy-for-centrally-located-lung-cancer
#3
Chang Gu, Xufeng Pan, Yong Chen, Jun Yang, Heng Zhao, Jianxin Shi
OBJECTIVES: The aim of this study was to compare the short-term and mid-term results of patients with centrally located lung cancer who underwent bronchial sleeve resection by robotic system or thoracotomy. METHODS: From September 2014 to September 2015, 103 patients, including 17 robotic and 86 open cases, were included in our study. All the clinicopathological data, operative details and follow-up information were investigated. RESULTS: There were no intraoperative deaths...
September 27, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/29028837/a-pilot-study-for-robot-appearance-preferences-among-high-functioning-individuals-with-autism-spectrum-disorder-implications-for-therapeutic-use
#4
Hirokazu Kumazaki, Zachary Warren, Taro Muramatsu, Yuichiro Yoshikawa, Yoshio Matsumoto, Masutomo Miyao, Mitsuko Nakano, Sakae Mizushima, Yujin Wakita, Hiroshi Ishiguro, Masaru Mimura, Yoshio Minabe, Mitsuru Kikuchi
Recent rapid technological advances have enabled robots to fulfill a variety of human-like functions, leading researchers to propose the use of such technology for the development and subsequent validation of interventions for individuals with autism spectrum disorder (ASD). Although a variety of robots have been proposed as possible therapeutic tools, the physical appearances of humanoid robots currently used in therapy with these patients are highly varied. Very little is known about how these varied designs are experienced by individuals with ASD...
2017: PloS One
https://www.readbyqxmd.com/read/29027948/comparing-the-performance-of-indoor-localization-systems-through-the-evaal-framework
#5
Francesco Potortì, Sangjoon Park, Antonio Ramón Jiménez Ruiz, Paolo Barsocchi, Michele Girolami, Antonino Crivello, So Yeon Lee, Jae Hyun Lim, Joaquín Torres-Sospedra, Fernando Seco, Raul Montoliu, Germán Martin Mendoza-Silva, Maria Del Carmen Pérez Rubio, Cristina Losada-Gutiérrez, Felipe Espinosa, Javier Macias-Guarasa
In recent years, indoor localization systems have been the object of significant research activity and of growing interest for their great expected social impact and their impressive business potential. Application areas include tracking and navigation, activity monitoring, personalized advertising, Active and Assisted Living (AAL), traceability, Internet of Things (IoT) networks, and Home-land Security. In spite of the numerous research advances and the great industrial interest, no canned solutions have yet been defined...
October 13, 2017: Sensors
https://www.readbyqxmd.com/read/29027935/robust-stereo-visual-odometry-using-improved-ransac-based-methods-for-mobile-robot-localization
#6
Yanqing Liu, Yuzhang Gu, Jiamao Li, Xiaolin Zhang
In this paper, we present a novel approach for stereo visual odometry with robust motion estimation that is faster and more accurate than standard RANSAC (Random Sample Consensus). Our method makes improvements in RANSAC in three aspects: first, the hypotheses are preferentially generated by sampling the input feature points on the order of ages and similarities of the features; second, the evaluation of hypotheses is performed based on the SPRT (Sequential Probability Ratio Test) that makes bad hypotheses discarded very fast without verifying all the data points; third, we aggregate the three best hypotheses to get the final estimation instead of only selecting the best hypothesis...
October 13, 2017: Sensors
https://www.readbyqxmd.com/read/29027639/robotic-laparoendoscopic-single-site-benign-gynecologic-surgery-a-single-center-experience
#7
J Jayakumaran, K Wiercinski, C Buffington, A Caceres
The da Vinci Xi surgical system was released with several upgrades and modifications compared to the previous robotic generations to facilitate minimal invasive surgery. Herein, we present our preliminary experience of robotic laparoendoscopic single-site gynecologic surgery performed for benign indications with the da Vinci Xi robotic system in a single center. Thirty-five female patients underwent robotic single-site surgery between June 2016 and January 2017. The median console time for hysterectomy with or without salpingo-oophorectomy was 41 min...
October 13, 2017: Journal of Robotic Surgery
https://www.readbyqxmd.com/read/29027400/surgical-and-oncologic-outcomes-after-robotic-radical-hysterectomy-as-compared-to-open-radical-hysterectomy-in-the-treatment-of-early-cervical-cancer
#8
Chirag A Shah, Tiffany Beck, John B Liao, Nadia V Giannakopoulos, Dan Veljovich, Pam Paley
OBJECTIVE: The use of robotic radical hysterectomy has greatly increased in the treatment of early stage cervical cancer. We sought to compare surgical and oncologic outcomes of women undergoing robotic radical hysterectomy compared to open radical hysterectomy. METHODS: The clinic-pathologic, treatment, and recurrence data were abstracted through an Institutional Review Board-approved protocol at 2 separate large tertiary care centers in Seattle, Swedish Medical Center and the University of Washington...
November 2017: Journal of Gynecologic Oncology
https://www.readbyqxmd.com/read/29027359/a-master-manipulator-with-a-remote-center-of-motion-kinematic-structure-for-a-minimally-invasive-robotic-surgical-system
#9
Hyunyoung Lee, Byungsik Cheon, Minho Hwang, Donghoon Kang, Dong-Soo Kwon
BACKGROUND: In robotic surgical systems, commercial master devices have limitations owing to insufficient workspace and lack of intuitiveness. To overcome these limitations, a remote-center-of-motion (RCM) master manipulator was proposed. METHODS: The feasibility of the proposed RCM structure was evaluated through kinematic analysis using a conventional serial structure. Two performance comparison experiments (peg transfer task and objective transfer task) were conducted for the developed master and Phantom Omni...
October 12, 2017: International Journal of Medical Robotics + Computer Assisted Surgery: MRCAS
https://www.readbyqxmd.com/read/29027351/robotic-assisted-versus-open-radical-cystectomy-in-bladder-cancer-a-meta-analysis-of-four-randomized-controlled-trails
#10
Jin-Qiu Tang, Zhihong Zhao, Yiwen Liang, Guixiang Liao
BACKGROUND: Robot-assisted radical cystectomy (RARC) is increasing annually for treatment of bladder cancer. The objective of this meta-analysis was to compare the safety and efficacy of RARC and open radical cystectomy (ORC) for bladder cancer. METHODS: Our meta-analysis searches were conducted using PubMed, Web of Science, and Cochrane Library databases to identify randomized controlled trials (RCT) assessing the two techniques. RESULTS: Four RCT studies were identified, including 239 cases...
October 12, 2017: International Journal of Medical Robotics + Computer Assisted Surgery: MRCAS
https://www.readbyqxmd.com/read/29027269/partial-nephrectomy-for-small-children-robot-assisted-versus-open-surgery
#11
Quentin Ballouhey, Aurélien Binet, Pauline Clermidi, Karim Braik, Thierry Villemagne, Jérôme Cros, Hubert Lardy, Laurent Fourcade
OBJECTIVES: To compare the outcomes of robot-assisted heminephrectomy for duplex kidney in children with those of open heminephrectomy. METHODS: The present retrospective multicentric analysis reviewed the records of robot-assisted versus open heminephrectomy carried out for duplex kidney in children from 2007 to 2014. Demographic data, weight, surgical time, hospital stay, complications and outcome were recorded. Follow up was based on a clinical review, renal sonography and dimercaptosuccinic acid renal scintigraphy...
October 13, 2017: International Journal of Urology: Official Journal of the Japanese Urological Association
https://www.readbyqxmd.com/read/29027175/multiplexed-chip-seq-using-direct-nucleosome-barcoding-a-tool-for-high-throughput-chromatin-analysis
#12
Christophe D Chabbert, Sophie H Adjalley, Lars M Steinmetz, Vicent Pelechano
Chromatin immunoprecipitation followed by sequencing (ChIP-Seq) or microarray hybridization (ChIP-on-chip) are standard methods for the study of transcription factor binding sites and histone chemical modifications. However, these approaches only allow profiling of a single factor or protein modification at a time.In this chapter, we present Bar-ChIP, a higher throughput version of ChIP-Seq that relies on the direct ligation of molecular barcodes to chromatin fragments. Bar-ChIP enables the concurrent profiling of multiple DNA-protein interactions and is therefore amenable to experimental scale-up, without the need for any robotic instrumentation...
2018: Methods in Molecular Biology
https://www.readbyqxmd.com/read/29026937/-minimally-invasive-and-robotic-assisted-surgical-management-of-upper-gastrointestinal-cancer
#13
REVIEW
P P Grimminger, H F Fuchs
Total minimally invasive upper gastrointestinal resections are currently mainly performed in centers. The advantages include reduction of operative trauma, magnified enlargement of the operation field and the resulting improvement in operative precision. Robotic-assisted minimally invasive esophagectomy (RAMIE) and laparoscopic/thoracoscopic minimally invasive esophagectomy (MIE) are currently the most commonly performed strategies for esophageal cancer. Laparoscopic (MIG) and robotic-assisted gastrectomy (RAG) are the equivalent procedures for gastric cancer...
October 12, 2017: Der Chirurg; Zeitschrift Für Alle Gebiete der Operativen Medizen
https://www.readbyqxmd.com/read/29026878/robotic-assisted-live-donor-ileal-segmentectomy-for-intestinal-transplantation
#14
Guosheng Wu, Qianjing Li, Qingchuan Zhao, Weizhong Wang, Hai Shi, Mian Wang, Jianyong Zheng, Mengbing Li, Daiming Fan
BACKGROUND: Every effort should be made to optimize surgical techniques and to minimize potential morbidity rates associated with live donor operations. Advances in a minimally invasive approach by robotic surgery to donor nephrectomy have raised the possibility of applying this technique to live donor bowel resections for intestinal transplantation. METHODS: We report the first 5 consecutive cases of a robotic-assisted live donor ileal segmentectomy. We describe the technical aspects of the procedure, discuss the rationale for considering this option, and evaluate potential advantages of this approach...
October 2017: Transplantation Direct
https://www.readbyqxmd.com/read/29026518/castleman-s-disease-a-rare-presentation-in-a-retroperitoneal-accessory-spleen-treated-with-a-minimally-invasive-robotic-approach
#15
Fabio Sbrana, Dimin Zhou, Ina Zamfirova, Nathaniel Leonardi
Unicentric Castleman's disease (UCD) is a rare disorder of unknown etiology characterized by localized lymphoid tissue proliferation and interfollicular hypervascularity. A 33-year-old Caucasian female presented with vague abdominal discomfort and pain with pressure. Ultrasound and computed tomography detected a large peripancreatic mass. Robotic-assisted resection of the mass along with en bloc dissection of the encased left adrenal gland was done. Frozen section examination confirmed UCD hyaline vascular variant in a retroperitoneal accessory spleen...
October 2017: Journal of Surgical Case Reports
https://www.readbyqxmd.com/read/29026312/robot-assisted-versus-conventional-laparoscopic-operation-in-anus-preserving-rectal-cancer-a-meta-analysis
#16
Yongzhen Cui, Cheng Li, Zhongfa Xu, Yingming Wang, Yamei Sun, Huirong Xu, Zengjun Li, Yanlai Sun
OBJECTIVE: The aim of this meta-analysis is to provide recommendations for clinical practice and prevention of postoperative complications, such as circumferential resection margin (CRM) involvement, and compare the amount of intraoperative bleeding, safety, operative time, recovery, outcomes, and clinical significance of robot-assisted and conventional laparoscopic procedures in anus-preserving rectal cancer. METHODS: A literature search (PubMed) was performed to identify biomedical research papers and abstracts of studies comparing robot-assisted and conventional laparoscopic procedures...
2017: Therapeutics and Clinical Risk Management
https://www.readbyqxmd.com/read/29026030/helping-robots-blend-into-the-background
#17
Cecilia Laschi
No abstract text is available yet for this article.
October 13, 2017: Science
https://www.readbyqxmd.com/read/29025427/adaptive-hybrid-robotic-system-for-rehabilitation-of-reaching-movement-after-a-brain-injury-a-usability-study
#18
F Resquín, J Gonzalez-Vargas, J Ibáñez, F Brunetti, I Dimbwadyo, L Carrasco, S Alves, C Gonzalez-Alted, A Gomez-Blanco, J L Pons
BACKGROUND: Brain injury survivors often present upper-limb motor impairment affecting the execution of functional activities such as reaching. A currently active research line seeking to maximize upper-limb motor recovery after a brain injury, deals with the combined use of functional electrical stimulation (FES) and mechanical supporting devices, in what has been previously termed hybrid robotic systems. This study evaluates from the technical and clinical perspectives the usability of an integrated hybrid robotic system for the rehabilitation of upper-limb reaching movements after a brain lesion affecting the motor function...
October 12, 2017: Journal of Neuroengineering and Rehabilitation
https://www.readbyqxmd.com/read/29025351/utilization-of-robotic-arm-assisted-total-knee-arthroplasty-for-soft-tissue-protection
#19
Assem A Sultan, Nicolas Piuzzi, Anton Khlopas, Morad Chughtai, Nipun Sodhi, Michael A Mont
Despite the well-established success of total knee arthroplasty (TKA), iatrogenic ligamentous and soft tissue injuries are infrequent, but potential complications that can have devastating impact on clinical outcomes. These injuries are often related to technical errors and excessive soft tissue manipulation, particularly during bony resections. Recently, robotic-arm assisted TKA was introduced and demonstrated promising results with potential technical advantages over manual surgery in implant positioning and mechanical accuracy...
October 13, 2017: Expert Review of Medical Devices
https://www.readbyqxmd.com/read/29024735/quantitative-analysis-of-technological-innovation-in-urology
#20
Nikita R Bhatt, Niall F Davis, David M Dalton, T E D McDermott, Robert J Flynn, Arun Z Thomas, Rustom P Manecksha
OBJECTIVE: To assess major areas of technological innovation in urology in the last 20 years using patent and publication data. METHODS: Patent and MEDLINE databases were searched between 1980 and 2012 electronically using the terms urology OR urological OR urologist AND "surgeon" OR "surgical" OR "surgery". The patent codes obtained were grouped in technology clusters, then further analyzed with individual searches, and growth curves were plotted. Growth rates and patterns were analyzed, and patents were correlated with publications as a measure of scientific support and of clinical adoption...
October 9, 2017: Urology
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