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https://www.readbyqxmd.com/read/28747212/sublingual-misoprostol-and-hyperpyrexia-case-report-with-temperature-curve
#1
Paul Nkemtendong Tolefac, Jacqueline Ze Minkande
BACKGROUND: Misoprostol has a wide range of applications in obstetrics and gynaecology. It is widely recommended by WHO, FIGO and ACOG for the treatment of postpartum haemorrhage due to it safety and cost-effectiveness. However, usage might be associated to hyperpyrexia and shivering. CASE PRESENTATION: We present a 30 year old Cameroonian female gravida 1 para 1 who had a vaginal delivery at 40 weeks of gestation complicated by primary postpartum haemorrhage (PPH)...
July 26, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28740434/a-global-quantitative-survey-of-hemostatic-assessment-in-postpartum-hemorrhage-and-experience-with-associated-bleeding-disorders
#2
Andra H James, David L Cooper, Michael J Paidas
PURPOSE: Coagulopathy may be a serious complicating or contributing factor to postpartum hemorrhage (PPH), and should be promptly recognized to ensure proper bleeding management. This study aims to evaluate the approaches of obstetrician-gynecologists worldwide towards assessing massive PPH caused by underlying bleeding disorders. METHODS: A quantitative survey was completed by 302 obstetrician-gynecologists from 6 countries (the UK, France, Germany, Italy, Spain, and Japan)...
2017: International Journal of Women's Health
https://www.readbyqxmd.com/read/28715942/trends-in-conservative-procedures-and-peripartum-hysterectomy-rates-in-severe-postpartum-haemorrhage
#3
Choi Wah Kong, William Wing Kee
OBJECTIVE: To explore whether increase in use of second-line conservative surgical procedures will alter the rate of peripartum hysterectomies in management of severe postpartum haemorrhage (PPH). METHODS: This is a retrospective cohort. All pregnant patients with gestation >=28 weeks with severe PPH (>=1.5 L) within 72 hours of delivery from year 2000 to 2015 (16-year period) in an obstetric training unit was recruited. Basic patient anthropometric characteristics and the main causes for PPH were calculated...
July 17, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28705158/-no-patient-should-die-of-pph-just-for-the-lack-of-training-experiences-from-multi-professional-simulation-training-on-postpartum-hemorrhage-in-northern-tanzania-a-qualitative-study
#4
Signe Egenberg, Bjørg Karlsen, Deodatus Massay, Happiness Kimaro, Lars Edvin Bru
BACKGROUND: Postpartum hemorrhage (PPH) is a major cause of maternal morbidity and mortality. In Tanzania, PPH causes 25% of maternal deaths. Skilled attendance is crucial to saving the lives of mothers and their newborns during childbirth. This study is a follow-up after multi-professional simulation training on PPH in northern Tanzania. The purpose was to enhance understanding and gain knowledge of important learning features and outcomes related to multi-professional simulation training on PPH...
July 14, 2017: BMC Medical Education
https://www.readbyqxmd.com/read/28703925/role-of-prophylactic-oxytocin-in-the-third-stage-of-labor-physiologic-versus-pharmacologically-influenced-labor-and-birth
#5
REVIEW
Elise N Erickson, Christopher S Lee, Cathy L Emeis
INTRODUCTION: Maternity care providers administer oxytocin prophylactically to prevent postpartum hemorrhage (PPH). Prophylactic oxytocin is generally considered effective and safe and is promoted by national organizations for standardized use. In this article, the evidence supporting prophylactic oxytocin administration for women undergoing spontaneous labor and birth compared with women whose labors included administration of exogenous oxytocin for induction or augmentation is explored...
July 13, 2017: Journal of Midwifery & Women's Health
https://www.readbyqxmd.com/read/28692753/decreased-pulmonary-arterial-proportional-pulse-pressure-is-associated-with-increased-mortality-in-group-1-pulmonary-hypertension
#6
Hunter Mwansa, Kenneth C Bilchick, Alex M Parker, William Harding, Benjamin Ruth, Jamie L W Kennedy, Manu Mysore, Younghoon Kwon, Andrew Mihalek, Sula Mazimba
BACKGROUND: This study evaluated the utility of a novel index, pulmonary arterial (PA) proportional pulse pressure (PAPP; range 0-1, defined as [PA systolic pressure - PA diastolic pressure] / PA systolic pressure), in predicting mortality in patients with World Health Organization group 1 pulmonary hypertension (PH). HYPOTHESIS: Low PAPP is associated with increased 5-year mortality independent of a validated contemporary risk-prediction equation (Pulmonary Hypertension Connection [PHC] equation)...
July 10, 2017: Clinical Cardiology
https://www.readbyqxmd.com/read/28692181/time-to-test-tamponade
#7
G J Hofmeyr
The general surgical principle of applying direct pressure at the site of haemorrhage has been applied in the treatment of postpartum haemorrhage (PPH) by means of an assortment of inflatable devices introduced into the uterine cavity. Over the last 23 years several reports and reviews in the BJOG and elsewhere have documented the apparent effectiveness of uterine balloon tamponade (UBT) for treatment of PPH. A large study in 2016 reported a success rate after vaginal delivery of 89% (152/171) and concluded that intrauterine balloon tamponade is an effective method for treating severe PPH...
July 10, 2017: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28684639/comparative-effects-of-glucose-and-water-drinks-on-blood-pressure-and-cardiac-function-in-older-subjects-with-and-without-postprandial-hypotension
#8
Laurence G Trahair, Sharmalar Rajendran, Renuka Visvanathan, Matthew Chapman, Daniel Stadler, Michael Horowitz, Karen L Jones
Postprandial hypotension (PPH) occurs frequently and is thought to reflect an inadequate increase in cardiac output to compensate for the rise in splanchnic blood flow after a meal. Gastric distension by water attenuates the postprandial fall in blood pressure (BP). Cardiac hemodynamics (stroke volume (SV), cardiac output (CO), and global longitudinal strain (GLS)) have hitherto not been measured in PPH We sought to determine the comparative effects of water and glucose drinks on cardiac hemodynamics in healthy older subjects and individuals with PPH Eight healthy older subjects (age 71...
July 2017: Physiological Reports
https://www.readbyqxmd.com/read/28675429/evaluation-of-a-multifaceted-postpartum-hemorrhage-management-intervention-in-community-hospitals-in-southern-thailand
#9
Tippawan Liabsuetrakul, Kanokporn Palanukunwong, Anan Chinduereh, Nurlisa Oomudee
OBJECTIVE: To assess a multifaceted postpartum hemorrhage (PPH)-management intervention in community hospitals in Southern Thailand. METHODS: The present prospective study was conducted from November 1, 2012 to April 30, 2015. The medical records of women with PPH were collected before (January 1, 2011, and October 31, 2012) and after (March 1, 2013, and December 31, 2014) the implementation of a multifaceted PPH-management intervention at three community hospitals in Southern Thailand; these patients were compared with patients diagnosed with PPH at three control hospitals in the same provinces during the same time periods...
July 4, 2017: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/28675419/shock-progression-and-survival-after-use-of-a-condom-uterine-balloon-tamponade-package-in-women-with-uncontrolled-postpartum-hemorrhage
#10
Thomas F Burke, Sandra Danso-Bamfo, Moytrayee Guha, Monica Oguttu, Vincent Tarimo, Brett D Nelson
OBJECTIVE: To examine the outcomes of women in advanced shock from uncontrolled postpartum hemorrhage (PPH) who underwent placement of an Every Second Matters for Mothers and Babies Uterine Balloon Tamponade (ESM-UBT) device. METHODS: In a prospective case series, data were collected for women who received an ESM-UBT device at healthcare facilities in Kenya, Senegal, Sierra Leone, and Tanzania between September 1, 2012, and September 30, 2016. Shock class was assigned on the basis of recorded blood pressures and mental status at the time of UBT placement...
July 4, 2017: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/28673342/knowledge-and-provision-of-misoprostol-among-pharmacy-workers-in-senegal-a-cross-sectional-study
#11
Kate Reiss, Katharine Footman, Eva Burke, Nafissatou Diop, Ramatoulaye Ndao, Babacar Mane, Maaike van Min, Thoai D Ngo
BACKGROUND: Making misoprostol widely available for management of postpartum haemorrhage (PPH) and post abortion care (PAC) is essential for reducing maternal mortality. Private pharmacies (thereafter called "pharmacies") are integral in supplying medications to the general public in Senegal. In the case of misoprostol, pharmacies are also the main supplier to public providers and therefore have a key role in increasing its availability. This study seeks to understand knowledge and provision of misoprostol among pharmacy workers in Dakar, Senegal...
July 3, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/28650098/disparities-in-eurotransplant-liver-transplantation-waitlist-outcome-between-patients-with-and-without-exceptional-meld
#12
Andreas Umgelter, Alexander Hapfelmeier, Wouter Kopp, Marieke van Rosmalen, Xavier Rogiers, Markus Guba
BACKGROUND: The sickest-first principle in donor-liver allocation can be implemented by allocating organs to cirrhotic patients with the highest Model of End-stage Liver Disease (MELD) scores. For patients with other risk factors, standard (SE) and non-standard exceptions (NSE) have been developed. We investigated whether this system of matched MELD scores achieves similar outcome on the liver transplant waiting-list for various diagnostic groups in Eurotransplant (ET) countries with MELD-based individual allocation (Belgium, The Netherlands and Germany)...
June 26, 2017: Liver Transplantation
https://www.readbyqxmd.com/read/28647892/postprandial-hypotension-in-neurological-disorders-systematic-review-and-meta-analysis
#13
REVIEW
Antun Pavelić, Magdalena Krbot Skorić, Luka Crnošija, Mario Habek
PURPOSE: Postprandial hypotension (PPH) has been associated with increased risk of syncope, falls, stroke, angina and mortality. As the majority of patients with PPH are asymptomatic, the diagnosis is often overlooked. The aim of this study was to perform a systematic review and meta-analysis of available scientific evidence on the likelihood of PPH in neurological diseases. METHODS: A systematic review of the literature (PubMed library, Cochrane Database for Systematic Reviews and Cochrane Central Register of Controlled Trials for results up to January 2017) identified 327 studies, of which 11 reported the frequency of PPH in patients with neurological diseases compared to healthy controls...
June 24, 2017: Clinical Autonomic Research: Official Journal of the Clinical Autonomic Research Society
https://www.readbyqxmd.com/read/28625281/the-petra-perinatal-emergency-team-response-assessment-scale-a-high-fidelity-simulation-validation-study
#14
Mrinalini Balki, David Hoppe, David Monks, Lynn Sharples, Mary Ellen Cooke, Lawrence Tsen, Rory Windrim
OBJECTIVE: The objective of this study was to establish the validity and reliability of a new interdisciplinary teamwork assessment scale, the Perinatal Emergency Team Response Assessment (PETRA), to assess team dynamics during a simulated obstetric crisis. METHODS: This observational cohort study was conducted using high-fidelity simulation and multidisciplinary obstetric teams in order to evaluate the validity and reliability of the previously developed PETRA scale for the assessment of teamwork in the management of obstetric crises...
July 2017: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
https://www.readbyqxmd.com/read/28622635/management-of-parturients-with-factor-xi-deficiency-10year-case-series-and-review-of-literature
#15
REVIEW
Lynda Verghese, Efterpi Tingi, Jecko Thachil, Charles Hay, Louise Byrd
This is an article reviewing the management of pregnant women with factor XI (FXI) deficiency. Retrospective review of the electronic records of 67 pregnancies in 25 women with FXI deficiency over a ten-year period was undertaken. All women received care at St Mary's Tertiary Referral Obstetric/Haematology Clinic for some or all of their pregnancies. Outcome measures included antenatal complications, mode of delivery, anaesthesia provided and postpartum haemorrhage (PPH) and management required. A positive bleeding history was identified in 50% of women prior to pregnancy...
August 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/28610569/a-novel-tamponade-agent-for-management-of-post-partum-hemorrhage-adaptation-of-the-xstat-mini-sponge-applicator-for-obstetric-use
#16
Maria I Rodriguez, Jeffrey T Jensen, Kenton Gregory, Mary Bullard, Paul Longo, Jerry Heidel, Alison Edelman
BACKGROUND: Although uterine tamponade is an effective treatment for postpartum hemorrhage (PPH), current methods have key limitations in their use, particularly in low resource settings. The XStat™ Mini Sponge Dressing (MSD) is approved for the management of non-compressible wounds in the battlefield/trauma setting. The MSD applies highly compressed medical sponges capable of stopping high-flow arterial bleeding within seconds. The objective of our study was to adopt the MSD for use in managing PPH...
June 13, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/28590768/effect-of-hydroalcoholic-extract-of-capsella-bursa-pastoris-on-early-postpartum-hemorrhage-a-clinical-trial-study
#17
Sahar Ghalandari, Nourossadat Kariman, Zohre Sheikhan, Faraz Mojab, Moghadameh Mirzaei, Hadis Shahrahmani
OBJECTIVES: Postpartum hemorrhage (PPH) is one of three main causes of maternal mortality and a life-threatening condition throughout the world. PPH can have irreversible complications for the mother even if it does not lead to death. This study was conducted to determine the effect of hydroalcoholic extract of Capsella bursa pastoris on early PPH. DESIGN: The present study was a single-blinded, randomized, clinical trial. SETTING: The study was conducted in Afzalipour Hospital of Kerman in 2015...
June 7, 2017: Journal of Alternative and Complementary Medicine: Research on Paradigm, Practice, and Policy
https://www.readbyqxmd.com/read/28583092/postpartum-hemorrhage-prevention-in-nepal-a-program-assessment
#18
Swaraj Pradhan Rajbhandari, Kamal Aryal, Wendy R Sheldon, Bharat Ban, Senendra Raj Upreti, Kiran Regmi, Shilu Aryal, Beverly Winikoff
BACKGROUND: In 2009, the Nepal Ministry of Health and Population launched a national program for prevention of postpartum hemorrhage (PPH) during home births that features advance distribution of misoprostol to pregnant women. In the years since, the government has scaled-up the program throughout much of the country. This paper presents findings from the first large-scale assessment of the effectiveness of the advance distribution program. METHODS: Data collection was carried out in nine districts and all three ecological zones...
June 5, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/28577390/feasibility-of-the-von-willebrand-disease-prevent-trial
#19
Margaret V Ragni, Nicoletta Machin, Andra H James, Craig D Seaman, Lynn M Malec, Craig M Kessler, Barbara A Konkle, Peter A Kouides, Anne T Neff, Claire S Philipp, Maria M Brooks
BACKGROUND: Despite treatment, women with von Willebrand disease (VWD) have lower von Willebrand factor (VWF) levels and greater blood loss at delivery than controls. Current weight-based dosing does not account for the ~1.5-fold increase in blood volume in pregnancy. METHODS: To evaluate the feasibility of a trial to prevent postpartum hemorrhage (PPH), we reviewed pre-pregnancy and 8th month VWF levels in women with VWD with and without PPH following vaginal delivery, assessed VWF concentrate use at delivery by U...
May 25, 2017: Thrombosis Research
https://www.readbyqxmd.com/read/28570643/maternal-outcome-after-abdominal-packing-for-uncontrolled-postpartum-hemorrhage-despite-peripartum-hysterectomy
#20
Xavier Deffieux, Marie Vinchant, Ingrid Wigniolle, François Goffinet, Loïc Sentilhes
BACKGROUND: Intra-abdominal packing is a possible option for persistent bleeding following hysterectomy for postpartum hemorrhage. However, to date, only very limited data about maternal outcome after intra-abdominal packing for surgically uncontrolled hemorrhage following hysterectomy are available. The objective of the current study was to estimate maternal outcome after intra-abdominal packing following unsuccessful peripartum hysterectomy for postpartum hemorrhage. METHODS: A questionnaire was mailed to all maternity units performing more than 850 deliveries per year...
2017: PloS One
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