keyword
https://read.qxmd.com/read/38733296/uterine-artery-embolization-versus-hysterectomy-in-postpartum-hemorrhage-a-systematic-review-with-meta-analysis
#1
REVIEW
Miguel Godeiro Fernandez, Sarah Fernandez Coutinho de Carvalho, Bruna Almeida Martins, Felipe da Silva Mota Santos, Fernando Antonio Falcão Paixão Neto, Malu Oliveira de Araujo Medeiros, Patrick Bastos Metzger
PURPOSE: The objective of this study is to perform a meta-analysis comparing the effectiveness of uterine artery embolization (UAE) versus peripartum hysterectomy for acute refractory postpartum hemorrhage (PPH) control. MATERIALS AND METHODS: We systematically searched 6 medical databases for studies comparing UAE and hysterectomy in PPH. Outcomes examined were mortality, hospitalization duration (HD) in days, and red blood cells (RBC) units utilization. Statistical analysis used RevMan 5...
May 11, 2024: Journal of Endovascular Therapy
https://read.qxmd.com/read/38731527/microwave-assisted-atom-transfer-radical-cyclization-in-the-synthesis-of-3-3-dichloro-%C3%AE-and-%C3%AE-lactams-from-n-alkenyl-tethered-trichloroacetamides-catalyzed-by-rucl-2-pph-3-3-and-their-cytotoxic-evaluation
#2
JOURNAL ARTICLE
Faïza Diaba, Alexandra G Sandor, María Del Carmen Morán
An expeditious synthesis of γ- and δ-lactams from tethered alkenyl trichloroacetamides in the presence of 5% of RuCl2 (PPh3 )3 is reported. In this investigation we have demonstrated that microwave activation significantly enhances reaction rates, leading to the formation of the corresponding lactams in yields ranging from good to excellent. Thus, we have been able to prepare a wide range of lactams, including indole and morphan bicyclic scaffolds, where the corresponding reactions were completely diastereoselective...
April 28, 2024: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://read.qxmd.com/read/38731162/uterine-balloon-tamponade-under-ultrasound-guidance-in-women-with-postpartum-hemorrhage-a-retrospective-cohort-study
#3
JOURNAL ARTICLE
Chiara Germano, Flavia Girlando, Andrea Roberto Carosso, Alessandro Messina, Giulia Parpinel, Livio Leo, Rossella Attini, Alberto Revelli, Bianca Masturzo
Background: Postpartum hemorrhage (PPH) represents one of the principal causes of maternal mortality and morbidity worldwide. Uterine balloon tamponade (UBT) is recommended for the treatment of postpartum hemorrhage due to uterine atony in women who do not respond to pharmacological first-line treatment. The success of UBT in bleeding control is related to the correct positioning of the device, since incorrect insertion can be associated with ineffectiveness and requires time-consuming repositioning maneuvers, with a further increase in blood loss...
April 30, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38726911/trends-in-severe-postpartum-haemorrhage-among-nulliparous-women-with-spontaneous-onset-of-labour-a-population-based-cohort-study
#4
JOURNAL ARTICLE
Camilla Tjønneland Mentzoni, Kari Klungsøyr, Hilde Marie Engjom
OBJECTIVE: To investigate the incidence of severe postpartum haemorrhage among nulliparous women with a spontaneous onset of labour at term from 2000 to 2020. DESIGN: Population-based cohort study. SETTING: National, using the Medical Birth Registry of Norway. POPULATION: Women (n = 330 244) who gave birth to their first singleton child in a cephalic presentation after a spontaneous onset of labour at term...
May 10, 2024: BJOG: An International Journal of Obstetrics and Gynaecology
https://read.qxmd.com/read/38719306/strategies-for-optimising-early-detection-and-obstetric-first-response-management-of-postpartum-haemorrhage-at-caesarean-birth-a-modified-delphi-based-international-expert-consensus
#5
JOURNAL ARTICLE
Verónica Pingray, Caitlin R Williams, Fadhlun M Alwy Al-Beity, Edgardo Abalos, Sabaratnam Arulkumaran, Alejandro Blumenfeld, Brendan Carvalho, Catherine Deneux-Tharaux, Soo Downe, Alexandre Dumont, Maria Fernanda Escobar, Cherrie Evans, Sue Fawcus, Hadiza S Galadanci, Diem-Tuyet Thi Hoang, G Justus Hofmeyr, Caroline Homer, Ayodele G Lewis, Tippawan Liabsuetrakul, Pisake Lumbiganon, Elliott K Main, Judith Maua, Francis G Muriithi, Ashraf Fawzy Nabhan, Inês Nunes, Vanesa Ortega, Thuan N Q Phan, Zahida P Qureshi, Claudio Sosa, John Varallo, Andrew D Weeks, Mariana Widmer, Olufemi T Oladapo, Ioannis Gallos, Arri Coomarasamy, Suellen Miller, Fernando Althabe
OBJECTIVE: There are no globally agreed on strategies on early detection and first response management of postpartum haemorrhage (PPH) during and after caesarean birth. Our study aimed to develop an international expert's consensus on evidence-based approaches for early detection and obstetric first response management of PPH intraoperatively and postoperatively in caesarean birth. DESIGN: Systematic review and three-stage modified Delphi expert consensus. SETTING: International...
May 8, 2024: BMJ Open
https://read.qxmd.com/read/38713295/predictors-and-a-scoring-model-for-maternal-near-miss-and-maternal-death-in-southern-thailand-a-case-control-study
#6
JOURNAL ARTICLE
Wipawan Raktong, Rapphon Sawaddisan, Krantarat Peeyananjarassri, Chitkasaem Suwanrath, Alan Geater
PURPOSE: To identify predictors and develop a scoring model to predict maternal near-miss (MNM) and maternal mortality. METHODS: A case-control study of 1,420 women delivered between 2014 and 2020 was conducted. Cases were women with MNM or maternal death, controls were women who had uneventful deliveries directly after women in the cases group. Antenatal characteristics and complications were reviewed. Multivariate logistic regression and Akaike information criterion were used to identify predictors and develop a risk score for MNM and maternal mortality...
May 7, 2024: Archives of Gynecology and Obstetrics
https://read.qxmd.com/read/38710995/the-influence-of-uterine-fibroids-on-adverse-outcomes-in-pregnant-women-a-meta-analysis
#7
JOURNAL ARTICLE
Hong Li, Zhonghua Hu, Yuyan Fan, Yingying Hao
OBJECTIVE: The objective of the meta-analysis was to determine the influence of uterine fibroids on adverse outcomes, with specific emphasis on multiple or large (≥ 5 cm in diameter) fibroids. MATERIALS AND METHODS: We searched PubMed, Embase, Web of Science, ClinicalTrials.gov, China National Knowledge Infrastructure (CNKI), and SinoMed databases for eligible studies that investigated the influence of uterine fibroids on adverse outcomes in pregnancy...
May 6, 2024: BMC Pregnancy and Childbirth
https://read.qxmd.com/read/38710264/agnostic-identification-of-plasma-biomarkers-for-postpartum-hemorrhage-risk
#8
JOURNAL ARTICLE
Stéphanie E Reitsma, Julia R Barsoum, Kirk C Hansen, Alexa M Sassin, Monika Dzieciatkowska, Andra H James, Kjersti M Aagaard, Homa K Ahmadzia, Alisa S Wolberg
BACKGROUND: Postpartum hemorrhage (PPH) is difficult to predict, is associated with significant maternal morbidity, and is the leading cause of maternal mortality worldwide. The identification of maternal biomarkers that can predict increased PPH risk would enhance clinical care and may uncover mechanisms that lead to PPH. OBJECTIVE: This retrospective case-control study employed agnostic proteomic profiling of maternal plasma samples to identify differentially abundant proteins in controls and PPH cases...
May 4, 2024: American Journal of Obstetrics and Gynecology
https://read.qxmd.com/read/38709741/bioactive-glasses-modulate-anticancer-activity-and-other-polyphenol-related-properties-of-polyphenol-loaded-pcl-bioactive-glass-composites
#9
JOURNAL ARTICLE
Michal Dziadek, Kinga Dziadek, Kamila Checinska, Barbara Zagrajczuk, Katarzyna Cholewa-Kowalska
In this work, bioactive glass (BG) particles obtained by three different methods (melt-quenching, sol-gel, and sol-gel-EISA) were used as modifiers of polyphenol-loaded PCL-based composites. The composites were loaded with polyphenolic compounds (PPh) extracted from sage ( Salvia officinalis L.). It was hypothesized that BG particles, due to their different textural properties (porosity, surface area) and surface chemistry (content of silanol groups), would act as an agent to control the release of polyphenols from PCL/BG composite films and other significant properties associated with and affected by the presence of PPh...
May 6, 2024: ACS Applied Materials & Interfaces
https://read.qxmd.com/read/38707885/awareness-and-safety-of-covid-19-vaccination-in-pregnancy
#10
JOURNAL ARTICLE
Pragya Shree, Vandana Verma, Neetika Patel, Roshani Gupta, Kamayni Yadav
BACKGROUND: COVID-19 vaccines are safe in pregnancy, as they do not contain a live attenuated virus. Mass vaccination is a key to control the pandemic. Neonates have been shown to be susceptible to severe illness, so maternal vaccination is important to provide neonatal vaccination. METHODS: The present study was conducted for a period of one year from November 21, 2021 to October 2O, 2022 at the Department of Obstetrics and Gynecology A.S.J.S.A.T.D.S. medical college, Fatehpur...
April 2024: Journal of Obstetrics and Gynaecology of India
https://read.qxmd.com/read/38701406/evaluating-the-quality-of-postpartum-hemorrhage-nursing-care-plans-generated-by-artificial-intelligence-models
#11
JOURNAL ARTICLE
Emine Karacan
BACKGROUND: With the rapidly advancing technological landscape of health care, evaluating the potential use of artificial intelligence (AI) models to prepare nursing care plans is of great importance. PURPOSE: The purpose of this study was to evaluate the quality of nursing care plans created by AI for the management of postpartum hemorrhage (PPH). METHODS: This cross-sectional exploratory study involved creating a scenario for an imaginary patient with PPH...
April 3, 2024: Journal of Nursing Care Quality
https://read.qxmd.com/read/38700065/knowledge-and-factors-associated-with-active-management-of-the-third-stage-of-labor-in-sub-saharan-africa-a-systematic-review-and-meta-analysis
#12
REVIEW
Kelemu Abebe Gelaw, Yibeltal Assefa Atalay, Gedion Asnake Azeze, Alemker Molla Yitayew, Natnael Atnafu Gebeyehu
BACKGROUND: Postpartum hemorrhage (PPH) is one of the leading causes of maternal mortality in sub-Saharan Africa. Implementing active management in the third stage of labor has significantly reduced the incidence of PPH. Thus, understanding the level of healthcare providers' knowledge of active management in the third stage of labor can inform guidelines, policies, and practices for effectively preventing PPH. OBJECTIVE: This review aimed to assess the level of healthcare providers' knowledge and associated factors of active management in the third stage of labor in sub-Saharan Africa...
May 3, 2024: International Journal of Gynaecology and Obstetrics
https://read.qxmd.com/read/38693914/-piriformospora-indica-suppresses-the-symptoms-produced-by-banana-bract-mosaic-virus-by-inhibiting-its-replication-and-manipulating-chlorophyll-and-carotenoid-biosynthesis-and-degradation-in-banana
#13
JOURNAL ARTICLE
K Sinijadas, Amitha Paul, N S Radhika, Joy Michal Johnson, R V Manju, T Anuradha
UNLABELLED: Banana bract mosaic virus (BBrMV) infection results in characteristic reddish streaks on pseudostem and chlorotic spindle lesions on leaves leading to traveler's palm appearance and complete crop loss depending on the stage of infection in banana plants. Here, we discuss the influence of P. indica colonization (a beneficial fungal root endophyte) on BBrMV infection, specific viral component genes responsible for symptom development, chlorophyll and carotenoid biosynthesis, and degradation in BBrMV-infected banana plants...
May 2024: 3 Biotech
https://read.qxmd.com/read/38693193/a-novel-low-cost-uterine-balloon-tamponade-kit-to-tackle-maternal-mortality-in-low-resource-settings
#14
JOURNAL ARTICLE
Sara Candidori, Kasra Osouli, Serena Graziosi, Alberto Antonio Zanini, Maria Laura Costantino, Francesco De Gaetano
The 3.1 target of the Sustainable Development Goals of the United Nations aims to reduce the global maternal mortality ratio to less than 70 maternal deaths per 100,000 live births by 2030. The last updates on this target show a significant stagnation in the data, thus reducing the chance of meeting it. What makes this negative result even more serious is that these maternal deaths could be avoided through prevention and the wider use of pharmacological strategies and devices to stop postpartum haemorrhage (PPH)...
May 1, 2024: Scientific Reports
https://read.qxmd.com/read/38686455/burden-and-outcomes-of-postpartum-haemorrhage-in-nigerian-referral-level-hospitals
#15
JOURNAL ARTICLE
Tajudeen Adebayo, Ayodeji Adefemi, Idowu Adewumi, Opeyemi Akinajo, Bola Akinkunmi, David Awonuga, Olufemi Aworinde, Ekundayo Ayegbusi, Iyabode Dedeke, Iretiola Fajolu, Zainab Imam, Olusoji Jagun, Olumide Kuku, Ezra Ogundare, Timothy Oluwasola, Lawal Oyeneyin, Damilola Adebanjo-Aina, Emmanuel Adenuga, Alaruru Adeyanju, Olufemi Akinsanya, Ibijoke Campbell, Bankole Kuti, Babatunde Olofinbiyi, Qasim Salau, Olukemi Tongo, Bosede Ezekwe, Tina Lavin, Olufemi T Oladapo, Jamilu Tukur, Olubukola Adesina
OBJECTIVE: To determine the prevalence of primary postpartum haemorrhage (PPH), risk factors, and maternal and neonatal outcomes in a multicentre study across Nigeria. DESIGN: A secondary data analysis using a cross-sectional design. SETTING: Referral-level hospitals (48 public and six private facilities). POPULATION: Women admitted for birth between 1 September 2019 and 31 August 2020. METHODS: Data collected over a 1-year period from the Maternal and Perinatal Database for Quality, Equity and Dignity programme in Nigeria were analysed, stratified by mode of delivery (vaginal or caesarean), using a mixed-effects logistic regression model...
April 30, 2024: BJOG: An International Journal of Obstetrics and Gynaecology
https://read.qxmd.com/read/38679455/does-perioperative-hydrocortisone-or-indomethacin-improve-pancreatoduodenectomy-outcomes-a-triple-arm-randomized-placebo-controlled-trial
#16
JOURNAL ARTICLE
Kislay Kant, Zeeshan Ahmed, Rohit Dama, Monish Karunakaran, Prateek Arora, Pradeep Rebala, Guduru Venkat Rao
BACKGROUNDS/AIMS: This trial evaluated whether anti-inflammatory agents hydrocortisone (H) and indomethacin (I) could reduce major complications after pancreatoduodenectomy (PD). METHODS: Between June 2018 and June 2020, 105 patients undergoing PD with > 40% of acini on the intraoperative frozen section were randomized into three groups (35 patients per group): 1) intravenous H 100 mg 8 hourly, 2) rectal I suppository 100 mg 12 hourly, and 3) placebo (P) from postoperative day (POD) 0-2...
April 29, 2024: Annals of Hepato-Biliary-Pancreatic Surgery
https://read.qxmd.com/read/38678677/decline-in-home-births-associated-with-faster-increase-in-trend-of-postpartum-haemorrhage-and-manual-removal-of-the-placenta
#17
JOURNAL ARTICLE
Anna E Seijmonsbergen-Schermers, Lilian L Peters, Suze Jans, Corine J Verhoeven, Ank de Jonge
In this study we explored the relationship between home birth rates and increasing rates of postpartum haemorrhage (PPH) and manual removal of the placenta (MROP). Data were used from the Dutch national perinatal registry (2000-2014) of women in midwife-led care. Adjusting for place of birth flattened the increasing trends of PPH and MROP. By adjusting for place of birth, the rising trend of MROP among multiparous women disappeared. This suggests that if home birth rates had not declined, PPH and MROP rates might not have increased as much...
April 22, 2024: Sexual & Reproductive Healthcare: Official Journal of the Swedish Association of Midwives
https://read.qxmd.com/read/38673049/prognostic-role-of-initial-thromboelastography-in-emergency-department-patients-with-primary-postpartum-hemorrhage-association-with-massive-transfusion
#18
JOURNAL ARTICLE
Sang Min Kim, Chang Hwan Sohn, Hyojeong Kwon, Seung Mok Ryoo, Shin Ahn, Dong Woo Seo, Won Young Kim
BACKGROUND: The early prediction of the need for massive transfusions (MTs) and the preparation of blood products are essential for managing patients with primary postpartum hemorrhage (PPH). Thromboelastography (TEG) enables a thorough evaluation of coagulation status and is useful for guiding the treatment of hemorrhagic events in various diseases. We investigated the role of TEG in predicting the need for MT in patients with primary PPH. METHODS: A retrospective observational study was conducted in the emergency department (ED) of a university-affiliated, tertiary referral center between November 2015 and August 2023...
April 16, 2024: Journal of Personalized Medicine
https://read.qxmd.com/read/38672971/association-between-initial-fibrinogen-levels-and-the-need-for-massive-transfusion-in-emergency-department-patients-with-primary-postpartum-hemorrhage-a-retrospective-study-from-a-single-center-in-korea
#19
JOURNAL ARTICLE
Sungmin Park, Changhwan Sohn, Hyojeong Kwon, Sangmin Kim, Seungmok Ryoo, Shin Ahn, Dongwoo Seo, Wonyoung Kim
BACKGROUND: This study aimed to evaluate the association between initial fibrinogen levels and massive transfusion (MT) in emergency department (ED) patients with primary postpartum hemorrhage (PPH). METHODS: This retrospective study was conducted in the ED of a university-affiliated, tertiary referral center from January 2004 to August 2023. Patients were divided into two groups: the MT group, which included those who received a transfusion of 10 or more units of packed red blood cells within the first 24 h, and the Non-MT group...
March 26, 2024: Journal of Personalized Medicine
https://read.qxmd.com/read/38661069/use-of-18-f-fluorocholine-pet-ct-in-the-detection-of-primary-hyperparathyroidism-in-paediatrics-a-case-report
#20
Helena Martínez Sánchez, Francisca Moreno Macián, Sara León Cariñena, Carmen de Mingo Alemany, Lidia Blasco González, Raquel Sánchez Vañó
OBJECTIVES: The most common cause of primary hyperparathyroidism (PPH) in children is a parathyroid adenoma. Among this population, PPH exhibits higher levels of morbidity, severity and target organ involvement compared to adults. When there is suspicion of PPH, cervical ultrasound and 99m Tc-sestamibi SPECT/CT are the imaging test traditionally indicated. Among adults, the use of [18 F]fluorocholine PET/CT has shown a higher sensitivity than ultrasound and [99m Tc]sestamibi SPECT/CT, leading to an expanding adoption in recent years...
April 26, 2024: Journal of Pediatric Endocrinology & Metabolism: JPEM
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