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https://www.readbyqxmd.com/read/29681937/sheehan-s-syndrome-revisited-underlying-autoimmunity-or-hypoperfusion
#1
José Gerardo González-González, Omar David Borjas-Almaguer, Alejandro Salcido-Montenegro, René Rodríguez-Guajardo, Anasofia Elizondo-Plazas, Roberto Montes-de-Oca-Luna, René Rodríguez-Gutiérrez
Sheehan's syndrome remains a frequent obstetric complication with an uncertain pathophysiology. We aimed to assess the incidence of hypopituitarism (≥2 hormonal axis impairment) within the first six postchildbirth months and to determine the existence of anti-pituitary antibodies. From 2015 to 2017, adult pregnant women, who developed moderate to severe postpartum hemorrhage (PPH), were consecutively included in the study. Pituitary function was assessed 4 and 24 weeks after PPH. At the end of the study, anti-pituitary antibodies were assessed...
2018: International Journal of Endocrinology
https://www.readbyqxmd.com/read/29676572/asymmetric-synthesis-of-nonracemic-2-amino-6-helicenes-and-their-self-assembly-into-langmuir-films
#2
Manfred Karras, Jan Holec, Lucie Bednarova, Radek Pohl, Bernd Schmidt, Irena G Stará, Ivo Stary
Alternative ways of preparing nonracemic 2-amino[6]helicene derivatives were explored. The enantioselective [2 + 2 + 2] cycloisomerization of a nonchiral triyne under Ni(cod)2/(R)-QUINAP catalysis delivered the enantioenriched (+)-(P)-2-aminodibenzo[6]helicene derivative in 67% ee. An ultimate "point-to-helical" chirality transfer was observed in the cyclization of enantiopure triynes mediated by Ni(CO)2(PPh)2 affording (-)-(M)- or (+)-(P)-7,8-bis(p-tolyl)hexahelicen-2-amine in >99% ee as well as its benzoderivative in >99% ee...
April 20, 2018: Journal of Organic Chemistry
https://www.readbyqxmd.com/read/29667848/transarterial-embolization-for-postpartum-hemorrhage-lessons-learned
#3
Chen-Ju Fu, Wiwan Irama, Yon-Cheong Wong, Hsiao-Jung Tseng, Li-Jen Wang, Kee-Min Yeow, Cheng-Hsien Wu
Background Although transarterial embolization (TAE) can powerfully control postpartum hemorrhage (PPH), clinical failure of TAE is not uncommon. Purpose To discover whether any parameters could predict timely clinical failure of TAE, then whether a supplementary intervention could be promptly initiated. Material and Methods We retrospectively analyzed 118 TAE procedures in 113 patients with PPH performed at our institution between January 2012 and May 2015. The patients were divided into the following groups: clinically successful TAE and failed TAE...
January 1, 2018: Acta Radiologica
https://www.readbyqxmd.com/read/29665209/a-very-short-uranium-iv-rhodium-i-bond-with-net-double-dative-bonding-character
#4
Stephen Liddle, Erli Lu, Ashley Wooles, Mathew Gregson, Philip Cobb
Reaction of the uranium silyl-phosphino-carbene complex [U{C(SiMe3)(PPh2)}(BIPM)(μ-Cl)Li(TMEDA)(μ-TMEDA)0.5]2 (1, BIPM = C(PPh2NSiMe3)2; TMEDA = Me2NCH2CH2NMe2) with the rhodium chloride compound [Rh(μ-Cl)(COD)]2 (COD = cyclo-octadiene) affords the unprecedented heterotrimetallic UIV-RhI2 complex [U(Cl)2{C(PPh2NSiMe3)(PPh[C6H4]NSiMe3)}{Rh(COD)}{Rh(CH(SiMe3)(PPh2)}] (2). Complex 2 exhibits one, very short, uranium-rhodium distance that is by some margin the shortest uranium-rhodium bond on record, one of the shortest absolute uranium-metal distances generally, and the shortest actinide-transition metal bond in terms of formal shortness ratio...
April 17, 2018: Angewandte Chemie
https://www.readbyqxmd.com/read/29664053/labor-onset-oxytocin-use-and-epidural-anesthesia-for-vaginal-birth-after-cesarean-section-and-associated-effects-on-maternal-and-neonatal-outcomes-in-a-tertiary-hospital-in-china-a-retrospective-study
#5
Shao-Wen Wu, He Dian, Wei-Yuan Zhang
Background: In the mainland of China, the trial of labor after cesarean section is still a relatively new technique. In this study, we aimed to investigate the effects of labor onset, oxytocin use, and epidural anesthesia on maternal and neonatal outcomes for vaginal birth after cesarean section (VBAC) in a tertiary hospital in China. Methods: This was a retrospective study carried out on 212 VBAC cases between January 2015 and June 2017 in Beijing Obstetrics and Gynecology Hospital, Capital Medical University...
April 20, 2018: Chinese Medical Journal
https://www.readbyqxmd.com/read/29660298/postpartum-hemorrhage-new-insights-for-definition-and-diagnosis
#6
A Borovac-Pinheiro, R C Pacagnella, J G Cecatti, S Miller, A M El Ayadi, J P Souza, J Durocher, P D Blumenthal, B Winikoff
The current definition of postpartum hemorrhage (PPH) is inadequate for early recognition of this important cause of maternal mortality, responsible for more than 80,000 deaths worldwide in 2015. A stronger definition of PPH should include both blood loss and clinical signs of cardiovascular changes after delivery, which would help providers to more promptly and accurately identify PPH. Along with the amount of blood loss, clinical signs and specifically the Shock Index (heart rate divided by systolic blood pressure) appear to aid in more accurate diagnosis of PPH...
April 13, 2018: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29656684/nationwide-survey-of-severe-postpartum-haemorrhage-in-japan-an-exploratory-study-using-the-national-database-of-health-insurance-claims
#7
Mai Sato, Eiji Kondoh, Tomohide Iwao, Shusuke Hiragi, Kazuya Okamoto, Hiroshi Tamura, Haruta Mogami, Yoshitsugu Chigusa, Tomohiro Kuroda, Masaki Mandai, Ikuo Konishi, Genta Kato
AIM: The aim of this study was to investigate epidemiological and clinical aspects of severe postpartum haemorrhage (PPH) in Japan. METHODS: We used national health insurance claims from 2011 to 2014 provided by the Ministry of Health, Labour and Welfare. The data included randomly selected claims that covered 10% of all inpatients in October, a so-called sampling dataset (covering 1/120 inpatients per year). We extracted claims for transfused blood, and further narrowed down the claims by names of diseases linked to PPH...
April 15, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29628615/pelvic-artery-embolization-for-treatment-of-postpartum-hemorrhage
#8
REVIEW
Jonathan D Lindquist, Robert L Vogelzang
Postpartum hemorrhage (PPH) is the leading cause of maternal perinatal morbidity and mortality worldwide. Defined as greater than 500 mL blood loss after vaginal delivery, and greater than 1,000 mL blood loss after cesarean delivery, PPH has many causes, including uterine atony, lower genital tract lacerations, coagulopathy, and placental anomalies. Correction of coagulopathy and identification of the cause of bleeding are mainstays of treatment. Medical therapies such as uterotonics, balloon tamponade, pelvic artery embolization, and uterine-sparing surgical options are available...
March 2018: Seminars in Interventional Radiology
https://www.readbyqxmd.com/read/29623551/classification-of-uterine-artery-angiographic-images-a-predictive-factor-of-failure-in-uterine-artery-embolization-for-postpartum-hemorrhage
#9
Eisuke Ueshima, Koji Sugimoto, Takuya Okada, Naoto Katayama, Yutaka Koide, Keitaro Sofue, Mayumi Morizane, Kenji Tanimura, Masashi Deguchi, Masato Yamaguchi
PURPOSE: To justify a classification system for angiographic images of uterine artery embolization (UAE) for postpartum hemorrhage (PPH) and identify new risk factors associated with failed embolization. MATERIALS AND METHODS: A retrospective analysis of 63 consecutive patients who underwent UAE for severe PPH was performed. Uterine artery angiography (UA) before embolization was classified into two types: type 1 was defined as complete staining and type 2 was defined as partial staining of the uterine arteries...
April 5, 2018: Japanese Journal of Radiology
https://www.readbyqxmd.com/read/29622362/clinical-outcomes-of-23-patients-who-had-repeat-pelvic-arterial-embolisation-for-uncontrolled-post-partum-haemorrhage-at-a-single-centre
#10
W Choi, J H Shin, P H Kim, K Han, J Y Ohm, J H Kim, J W Kim
AIM: To evaluate the safety and efficacy of repeated pelvic arterial embolisation (PAE) for uncontrolled postpartum haemorrhage (PPH) after a single session of PAE and to compare angiographic findings between the two sessions of PAE. MATERIALS AND METHODS: A total of 23 consecutive patients (age range, 23-44 years) who underwent repeated PAE for uncontrolled PPH between March 2001 and January 2016 in Severance Hospital were reviewed. The interval times between the two sessions of PAE, the angiographic findings, embolic materials, arteries embolised during PAE, and the clinical outcomes were reviewed retrospectively...
April 2, 2018: Clinical Radiology
https://www.readbyqxmd.com/read/29603742/prognostic-factors-for-the-use-of-intrauterine-balloon-tamponade-in-the-management-of-severe-postpartum-hemorrhage
#11
Choi Wah Kong, William W To
OBJECTIVE: To identify prognostic factors associated with successful management of severe postpartum hemorrhage (PPH) using intrauterine balloon tamponade (IUBT). METHODS: Retrospective review of all cases of severe PPH with blood loss greater than 1 L in a tertiary unit in Hong Kong from July 1, 2012, to June 30, 2017. Records of patients who had undergone IUBT insertion were reviewed. Univariate analysis and logistic regression models were used to identify prognostic factors for successful management with IUBT...
March 31, 2018: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/29577215/-current-status-in-surgical-treatment-of-constipation
#12
Jiexuan Wang, Wei Cai
Chronic constipation is a polysymptomatic heterogeneous disorder with the incidence rising in many countries, and becomes a common disease affecting the quality of life and financial burden. In China surgical guideline, the primary constipation is divided into 3 types: slow transit constipation, outlet obstructive constipation, mixed constipation. The Rome IIII( criteria is usually referred to diagnosis, considering with clinical features and patient complaints. Through detail interrogation, physical examination and various detections, the secondary causes should be excluded, and etiological treatment is worth to try...
March 25, 2018: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/29575313/catalytic-hydrodefluorination-of-c-f-bonds-by-an-air-stable-p-iii-lewis-acid
#13
Saurabh Chitnis, Felix Krischer, Douglas Wade Stephan
Catalytic hydrodefluorination (HDF) of unactivated fluoroalkanes or CF3-substituted aryl species is performed using the P(III) Lewis acids, [(bipy)PPh]2+ (12+)and [(terpy)PPh]2+ (22+) under mild conditions (25 oC or 50 oC). Mechanistic studies indicate that activation of C-F bond by the P(III) center is key. Particularly noteworthy is that the catalyst 2[B(C6F5)4]2 is air-stable and readily accessible from bench-stable, commercially available reagents in one-step and can be used without isolation.
March 25, 2018: Chemistry: a European Journal
https://www.readbyqxmd.com/read/29573720/postpartum-blood-transfusion-and-hemorrhage-as-independent-risk-factors-for-venous-thromboembolism
#14
L Thurn, A Wikman, P G Lindqvist
INTRODUCTION: Profuse postpartum hemorrhage (PPH) and red blood cell (RBC) transfusion have been suggested to be associated with venous thromboembolic events (VTE). However, it is not fully clear if they are independent major risk factors. METHODS: Women who gave birth in the Stockholm area between 1999 and 2002 were those studied, i.e., before the implementation of guidelines for thromboprophylaxis in pregnancy. In this population-based cohort study the Swedish Medical Birth Registry was linked to the National Discharge Registry and to the transfusion database...
March 10, 2018: Thrombosis Research
https://www.readbyqxmd.com/read/29570928/an-organogold-iii-difluoride-with-trans-arrangement
#15
Babil Menjón, Alberto Pérez-Bitrián, Miguel Baya, José María Casas, Antonio Martín, Jesús Orduna
The trans isomer of the organogold(III) difluoride complex [PPh₄][(CF₃)₂AuF₂] has been obtained in a stereoselective way and in excellent yield by reaction of [PPh₄][CF₃AuCF₃] with XeF₂ under mild conditions. The compound is both thermally stable and reactive. Thus, the fluoride ligands are stereospecifically replaced by any heavier halide or by cyanide, the latter affording [PPh₄][trans-(CF₃)₂Au(CN)₂]. The organogold fluoride complexes [CF₃AuFx]⁻ (x = 1, 2, 3) have been experimentally detected to arise upon collision-induced dissociation of the [trans-(CF₃)₂AuF₂]⁻ anion in the gas phase...
March 23, 2018: Angewandte Chemie
https://www.readbyqxmd.com/read/29570453/anencephaly-and-obstetric-outcome-beyond-the-age-of-viability
#16
Sawsan Al-Obaidly, Jis Thomas, Mahmoud Abu Jubara, Abdullah Al Ibrahim, Mariam Al-Belushi, Najah Saleh, Zeena Al-Mansouri, Najat Khenyab
OBJECTIVE: To review the obstetric impact and natural history of anencephalic pregnancies beyond the age of viability. STUDY DESIGN: A retrospective chart review of all cases with a prenatal diagnosis of anencephaly who delivered after 24 weeks' gestation during the period 1990 until 2016. Obstetric outcomes including mode of delivery, live births, shoulder dystocia, antepartum haemorrhage (APH), postpartum haemorrhage (PPH) and uterine rupture were studied. RESULTS: A total of 42 cases were studied...
March 23, 2018: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/29569396/time-for-global-scale-up-not-randomized-trials-of-uterine-balloon-tamponade-for-postpartum-hemorrhage
#17
Thomas F Burke, Kusum Thapa, Poonam Shivkumar, Vincent Tarimo, Monica Oguttu, Lorraine Garg, Saroja Pande, Juzar Fidvi, Vidyadhar Bangal, José Ochoa, Archana Amatya, Melody Eckardt, Apollinaire Horo, Khama Rogo, Kshama Kedar, Albert Manasyan, Pragati Khalatkar, Susana Ku, Anders Seim, Sebastian Suarez, Moytrayee Guha, Khadija Abdalla, Carlos Fuchtner, Maria F Escobar, Sabaratnam Arulkumaran
No abstract text is available yet for this article.
March 22, 2018: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/29561462/rupture-of-multiple-pseudoaneurysms-as-a-rare-complication-of-common-iliac-artery-balloon-occlusion-in-a-patient-with-placenta-accreta-a-case-report-and-review-of-literature
#18
Qiaozhen Peng, Weishe Zhang
RATIONALE: Placenta accreta is the main cause of severe obstetric postpartum hemorrhage (PPH) and hysterectomy. Several hemostatic techniques have been performed in patients with placenta accreta to prevent PPH and reserve fertility. Abdominal aorta and pelvic arteries balloon occlusion are the only techniques which could be performed before cesarean section (CS) in patients who want to keep the fetus and reserve fertility. However, abdominal aorta and pelvic arteries balloon occlusion might lead to severe complications such as formation and rupture of pseudoaneurysm, angiorrhexis, etc...
March 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29558231/comparing-success-rates-of-the-hayman-compression-suture-and-the-bakri-balloon-tamponade
#19
Berna Aslan Cetin, Begum Aydogan Mathyk, Alev Atis Aydin, Nadiye Koroglu, Pinar Yalcin Bahat, Ilkbal Temel Yuksel, Elif Goknur Topcu, Ismail Ozdemir
BACKGROUND: Postpartum hemorrhage (PPH) is one of the leading causes of maternal morbidity and mortality around the world. Medical treatments and uterus-sparing interventions including balloon tamponades and compression sutures are the first line options before the decision is made to perform a hysterectomy. Our aim is to compare the success rates of the Hayman compression suture and the Bakri balloon tamponade in patients with PPH. METHODS: We enrolled 82 patients who were diagnosed with uterine atony during their cesarean sections and failed to respond to uterotonic agents...
March 20, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29535559/ebb-%C3%A2-complete-tamponade-system-effective-hemostasis-for-postpartum-hemorrhage
#20
REVIEW
Ross W McQuivey, Jon E Block, Robert A Massaro
As a leading cause of maternal death, postpartum hemorrhage (PPH) remains a worldwide obstetrical problem. However, in most cases, mortality and morbidity can be averted if efforts are immediately undertaken to achieve hemostasis. Uterine balloon tamponade has been shown to provide effective control of PPH and avoid more invasive surgical procedures and even the emergency peripartum hysterectomy. Recent clinical recommendation suggests that balloon tamponade should be considered earlier in the treatment cascade in conjunction with uterotonic agents to ensure hemostasis in the most timely fashion and maximize clinical outcomes...
2018: Medical Devices: Evidence and Research
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