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https://www.readbyqxmd.com/read/28429722/use-of-a-visual-aid-in-addition-to-a-collector-bag-to-evaluate-postpartum-blood-loss-a-prospective-simulation-study
#1
M Brooks, G Legendre, S Brun, P-E Bouet, L Pereira Mendes, B Merlot, L Sentilhes
Postpartum hemorrhage (PPH) is one of the most common causes of mortality in obstetrics worldwide. The accuracy of estimated blood loss is a priority in determining appropriate treatment. Will the additional use of a visual aid improve physicians' accuracy in estimating blood loss compared to the use of a collector bag and baby scale alone? Simulation training sessions created three vaginal delivery scenarios for participants to estimate volumes of blood loss: firstly, using only a collector bag and a baby weight scale and secondly, adding a visual aid depicting known volumes of blood...
April 21, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28422884/posterior-reversible-encephalopathy-syndrome-in-a-postpartum-hemorrhagic-woman-without-hypertension-a-case-report
#2
Chon-Fu Lio, Ying-Hua Lee, Hung-Yen Chan, Chang-Ching Yu, Nan-Jing Peng, Hung-Pin Chan
RATIONALE: Posterior reversible encephalopathy syndrome (PRES), which diagnosis is based on clinical symptoms and radiological features, is a neurotoxic disease characterized by a set of clinical manifestations, such as seizure, headache, visual, and/or consciousness disturbance. It is the first case of PRES followed by postpartum hemorrhage (PPH) without underlying disease. PATIENT CONCERNS: A 37-year-old healthy woman had PPH after caesarean section. Six days after delivery, headache occurred suddenly, followed by episodes of clonus seizure...
April 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28421908/extravasating-uterine-pseudoaneurysm-a-rare-cause-of-postpartum-haemorrhage
#3
Sang Wook Yi
Postpartum haemorrhage (PPH) remains one of the leading causes of maternal death worldwide and can be classified as either immediate (primary) or delayed (secondary) according to the onset time - before or after 24 hours postpartum. Uterine pseudoaneurysm is a rare cause of PPH that has been suggested to arise from abnormal vascular regression and a recurrent vascular healing state, such as a vascular stricture and relaxation with thrombin deposits after placental expulsion. With advances in multidetector computed tomography, 3D-computed tomography with angiography can aid in identifying the location and originating vessels of the pseudoaneurysm via fast and clear 3D images...
May 2017: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28421545/the-association-between-the-time-from-oxytocin-cessation-during-labour-to-cesarean-delivery-and-postpartum-blood-loss-a-retrospective-cohort-study
#4
Gary Tran, Marcelo Kanczuk, Mrinalini Balki
PURPOSE: Prolonged exposure to oxytocin during augmentation of labour is associated with uterine atony and an increased risk of postpartum hemorrhage (PPH) due to oxytocin receptor desensitization. Cessation of oxytocin infusion during labour may facilitate recovery of oxytocin receptor function, which then helps to restore myometrial contractility and decrease postpartum blood loss. We examined the association between oxytocin recovery interval, i.e., the time from discontinuing oxytocin to Cesarean delivery (CD) for labour arrest, and blood loss...
April 18, 2017: Canadian Journal of Anaesthesia, Journal Canadien D'anesthésie
https://www.readbyqxmd.com/read/28413832/statistical-analysis-plan-for-the-woman-etaplat-study-effect-of-tranexamic-acid-on-platelet-function-and-thrombin-generation
#5
Kastriot Dallaku, Haleema Shakur, Phil Edwards, Danielle Beaumont, Ian Roberts, Sumaya Huque, Maria Delius, Ulrich Mansmann
Background. Postpartum haemorrhage (PPH) is a potentially life-threatening complication for women, and the leading cause of maternal mortality. Tranexamic acid (TXA) is an antifibrinolytic used worldwide to treat uterine haemorrhage and to reduce blood loss in general surgery. TXA may have effects on thrombin generation, platelet function and coagulation factors as a result of its inhibition on the plasmin. Methods. WOMAN ETAPlaT is a sub-study of the World Maternal Antifibrinolitic trial (WOMAN trial). All adult women clinically diagnosed with PPH after a vaginal delivery or caesarean section, are eligible for inclusion in the study...
December 15, 2016: Wellcome Open Research
https://www.readbyqxmd.com/read/28403951/successful-use-of-a-bakri-tamponade-balloon-in-the-treatment-of-puerperal-uterine-inversion-during-caesarean-section
#6
A J Vivanti, E Furet, J Nizard
Acute puerperal inversion of the uterus is a rare life-threatening obstetric emergency, especially during caesarean section. We present the case of a 30-year-old patient with acute puerperal inversion of the uterus that occurred during placental removal. After a quick reversion of the uterus, an immediate postpartum haemorrhage (PPH) due to massive uterine atony was observed. This atony impacted the whole uterus, with a very thin uterine myometrium. The use of a Bakri Tamponade Balloon use allowed treating extreme uterine atony, immediately stop haemorrhage, and prevent a possible risk of immediate recurrence...
January 2017: J Gynecol Obstet Hum Reprod
https://www.readbyqxmd.com/read/28384942/recent-advances-in-the-management-of-major-postpartum-haemorrhage-a-review
#7
REVIEW
P Reddi Rani, Jasmina Begum
Postpartum haemorrhage (PPH) is a leading cause of maternal mortality and morbidity worldwide and 75-90% of these haemorrhage results from uterine atony. Delayed and substandard obstetrics care can kill a woman within hours of Major Obstetric Haemorrhage (MOH). Prenatal identification of at risk women, prompt assessment of blood loss, effective management and involvement of multidisciplinary teams is of utmost importance to save the lives of these women. However, even with the best prenatal care, PPH occurs, it can occur without any risk factors...
February 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28384938/misoprostol-induced-convulsion-a-rare-side-effect-of-misoprostol
#8
Nalini Sharma, Rituparna Das, Santa Singh Ahanthem, Kalyani Reddy
Misoprostol, a synthetic prostaglandin E1 has wider application in obstetrics gynaecology. It has been recommended in the prophylaxis and treatment of Post Partum Haemorrhage (PPH) by Federation of Obstetrics and Gynaecology (FIGO), World Health Organisation (WHO) and American College of Obstetrics and Gynaecology (ACOG). It is a very safe drug associated with transient side-effects like fever, chills, nausea, vomiting, diarrhoea and abdominal pain. In the present case report patient had an unusual side effect of hyperpyrexia and convulsion after use of misoprostol for prophylaxis against PPH...
February 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28384642/incidence-of-and-risk-factors-and-reinterventions-for-post-pancreatoduodenectomy-hemorrhage-retrospective-analysis
#9
Wei-Guo Wang, Lan Fu, Shah Ram Babu, Li Wang, Cui-Ping Liang, Bo-Le Tian
AIMS: To analyze the incidence of and risk factors for post-pancreatoduodenectomy (PD) hemorrhage (PPH) and to evaluate the outcomes of reinterventions for PPH. METHODS: All PDs between January 2009 and December 2014 were retrospectively evaluated. PPH was evaluated according to the criteria of the International Study Group of Pancreatic Surgery. Both univariate and multivariate analyses of risk factors for PPH and mortality were performed. Reinterventions were also evaluated...
April 7, 2017: Digestive Surgery
https://www.readbyqxmd.com/read/28378864/large-weakly-basic-bis-carboranyl-phosphines-an-experimental-and-computational-study
#10
Laura E Riley, Tobias Krämer, Claire L McMullin, David Ellis, Georgina M Rosair, Igor B Sivaev, Alan J Welch
The bis(carboranyl)phosphines [μ-2,2'-PPh-{1-(1'-1',2'-closo-C2B10H10)-1,2-closo-C2B10H10}] (I) and [μ-2,2'-PEt-{1-(1'-1',2'-closo-C2B10H10)-1,2-closo-C2B10H10}] (1) have been prepared and spectroscopically and structurally characterised. Crystallographic and DFT computational studies of 1 suggest that the orientation of the ethyl group, relative to the bis(carborane), is the result of intramolecular dihydrogen bonding. This orientation is such that the magnitudes of the (2)JPH coupling constants are approximately equal but of opposite sign, and fast exchange between the methylene protons in solution leads to an observed (2)JPH close to zero...
April 19, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/28378322/disparities-in-potentially-preventable-hospitalizations-near-national-estimates-for-hispanics
#11
Chen Feng, Michael K Paasche-Orlow, Nancy R Kressin, Jennifer E Rosen, Lenny López, Eun Ji Kim, Meng-Yun Lin, Amresh D Hanchate
OBJECTIVE: To obtain near-national rates of potentially preventable hospitalization (PPH)-a marker of barriers to outpatient care access-for Hispanics; to examine their differences from other race-ethnic groups and by Hispanic national origin; and to identify key mediating factors. DATA SOURCES/STUDY SETTING: Data from all-payer inpatient discharge databases for 15 states accounting for 85 percent of Hispanics nationally. STUDY DESIGN: Combining counts of inpatient discharges with census population for adults aged 18 and older, we estimated age-sex-adjusted PPH rates...
April 4, 2017: Health Services Research
https://www.readbyqxmd.com/read/28374064/probable-postpartum-hypomania-and-depression-in-a-south-african-cohort
#12
Janine Pingo, Leigh L van den Heuvel, Bavinisha Vythylingum, Soraya Seedat
The aim of this study was to evaluate the frequency of, and factors associated with, postpartum hypomania (PPH) and postpartum depression (PPD) in a South African sample. Data from 57 women were analysed as part of a larger prospective study of maternal stress in pregnancy. On day 3 postpartum, women were assessed for probable PPH using the Highs scale. On day 3 and at week 6, probable PPD was assessed using the Edinburgh Postnatal Depression Scale (EPDS), while social support was evaluated using the Multidimensional Scale of Perceived Social Support (MSPSS)...
April 4, 2017: Archives of Women's Mental Health
https://www.readbyqxmd.com/read/28370811/preparation-and-characterization-of-novel-group-13-cyanides
#13
Ralf Haiges, Piyush Deokar, Monica Vasiliu, Trent H Stein, David A Dixon, Karl Christe
The novel binary Group 13 cyanides [PPh₄][Ga(CN)₄], [PPh₄]₂[In(CN)₅] and [PPh₄]₂[Tl(CN)₅] were obtained in quantitative yields from the corresponding metal trifluorides [MF₃] (M = Ga, In, Tl) by fluoride-cyanide exchange reactions with Me₃SiCN in the presence of stoichiometric amounts of [PPh₄][CN] in acetonitrile solution. The 2,2'-bipyridine (bipy) adducts [(bipy)₂Ga(CN)₂][Ga(CN)₄], [(bipy)In(CN)₃] and [(bipy)Tl(CN)₃] were obtained from the reaction of [MF₃] with Me₃SiCN and bipy in acetonitrile...
April 2, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/28370714/modulating-the-bonding-properties-of-n-heterocyclic-carbenes-nhcs-a-systematic-charge-displacement-analysis
#14
Paola Belanzoni, Carlo Alberto Gaggioli, Giovanni Bistoni, Gianluca Ciancaleoni, Francesco Tarantelli, Leonardo Belpassi
In this paper we provide a quantitative analysis of the chemical bond between a metal fragment AuCl and a series of 29 different NHCs in [(NHC)AuCl] complexes. NHCs electronic properties are modified through a: i) variation of the groups attached to the NHC nitrogen atoms or backbone, ii) change of unsaturation/size of the NHC ring, iii) inclusion of paracyclophane moieties, or iv) heteroatom substitution on the NHC ring. For evaluating the donation and back-donation components of the Dewar-Chatt-Duncanson (DCD) model in the NHCs-AuCl bond, we apply the CD-NOCV analysis, a methodology that avoids the constraint of using symmetrized structures...
April 3, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/28369818/double-balloon-tamponade-for-postpartum-hemorrhage
#15
Michael Breen
No abstract text is available yet for this article.
March 31, 2017: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/28357716/in-vitro-cytotoxicity-assessment-of-a-west-virginia-chemical-spill-mixture-involving-4-methylcyclohexanemethanol-and-propylene-glycol-phenyl-ether
#16
Alice A Han, Emily B Fabyanic, Julie V Miller, Maren S Prediger, Nicole Prince, Julia A Mouch, Jonathan Boyd
Thousands of gallons of industrial chemicals, crude 4-methylcyclohexanemethanol (MCHM) and propylene glycol phenyl ether (PPh), leaked from industrial tanks into the Elk River in Charleston, West Virginia, USA, on January 9, 2014. A considerable number of people were reported to exhibit symptoms of chemical exposure and an estimated 300,000 residents were advised not to use or drink tap water. At the time of the spill, the existing toxicological data of the chemicals were limited for a full evaluation of the health risks, resulting in concern among those in the impacted regions...
April 2017: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/28355654/experience-of-point-of-care-devices-in-obstetrical-care
#17
Ove Karlsson
During pregnancy and puerperium, there are pronounced hemostatic changes characterized by increased coagulability and decreased fibrinolysis. In addition, hemostasis can change dramatically during obstetric complications. Several reports have described substandard management of hemostatic defects in this setting and state the need for guidelines and better care. Point-of-care devices can assess hemostatic status and are especially suitable in perioperative settings. Using point-of-care devices, no time is required for transportation, allowing faster availability of results and providing potential for better care of the patient...
March 29, 2017: Seminars in Thrombosis and Hemostasis
https://www.readbyqxmd.com/read/28355242/fluoroscopy-free-resuscitative-endovascular-balloon-occlusion-of-the-aorta-reboa-for-controlling-life-threatening-postpartum-hemorrhage
#18
Knut Haakon Stensaeth, Edmund Sovik, Ingrid Natasha Ylva Haig, Erna Skomedal, Arve Jorgensen
BACKGROUND: Severe postpartum hemorrhage occurs in 1/1000 women giving birth. This condition is often dramatic and may be life threatening. Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA) has in recent years been introduced as a novel treatment for hemorrhagic shock. We present a series of fluoroscopy-free REBOA for controlling life threatening postpartum hemorrhage. METHODS: In 2008 an 'aortic occlusion kit' was assembled and used in three Norwegian university hospitals...
2017: PloS One
https://www.readbyqxmd.com/read/28317421/a-prospective-cohort-study-evaluating-the-cost-effectiveness-of-carbetocin-for-prevention-of-postpartum-haemorrhage-in-caesarean-sections
#19
Yasmin Luni, Aditya Borakati, Arti Matah, Katie Skeats, Padma Eedarapalli
Postpartum haemorrhage (PPH) is the leading cause of maternal mortality worldwide. Prophylaxis with oxytocic medication is recommended by the WHO to prevent its occurrence. Carbetocin is a newer oxytocic, with potential to lower PPH rates, reduce the total use of oxytocic drugs and lead to financial savings. Meta-analyses have confirmed a reduction in the use of additional oxytocic medication with the use of carbetocin compared to oxytocin. However, there are few studies evaluating the costs of carbetocin prophylaxis...
March 20, 2017: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28317201/anionic-derivatives-of-perfluorinated-trimethylgold
#20
Babil Menjón, Alberto Pérez-Bitrián, Sonia Martínez-Salvador, Miguel Baya, José María Casas, Antonio Martín, Jesús Orduna
The homoleptic compound [PPh₄][CF₃AuCF₃] cleanly undergoes photoinduced oxidative addition of CF₃I to afford the organogold(III) derivative [PPh₄][(CF₃)₃AuI] in good yield and under mild conditions. This compound provides a convenient entry to the chemistry of the perfluorinated (CF₃)₃Au fragment whose properties are analyzed with the aid of DFT methods and compared with those of the homologous non-fluorinated (CH₃)₃Au moiety. It is found that reductive elimination of CX₃-CX₃ in the former (X = F) requires a much higher energy barrier than in the latter (X = H) and is therefore considerably less favored...
March 20, 2017: Chemistry: a European Journal
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