keyword
MENU ▼
Read by QxMD icon Read
search

rheumatoid arthritis mimicking

keyword
https://www.readbyqxmd.com/read/29421221/folate-conjugated-superoxide-dismutase-adsorbed-over-antioxidant-mimicking-nanomatrix-frameworks-for-treatment-of-rheumatoid-arthritis
#1
Shikha Srivastava, Deependra Singh, Manju R Singh
Rheumatoid arthritis (RA) is an autoimmune disease occurring in larger population, characterized by synovial inflammation followed by destruction of joint. Major concerned factor for cause of Rheumatoid arthritis (RA) has been related to oxidative stress due to environmental toxicity and immune imbalance. Reactive oxygen species (ROS) generated from macrophages commune series of oxidation at cellular and genetic level and leads to generation of inflammatory cytokines for provoking inflammation in RA. Superoxide Dismutase (SOD) and catalase (CAT) are supposed to be potential antioxidant enzymes to scavange free radicals...
February 5, 2018: Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29390551/xanthomatosis-in-bilateral-hands-mimicking-rheumatoid-arthritis-a-case-report
#2
Dan Li, Longfei You, Songqing Fan, Lihua Tan
RATIONALE: Xanthomatosis often accompanies familial hypercholesterolemia. This disease usually occurs in tendons, most commonly located in the Achilles tendon; occasionally it can also be seen in other systems. Although there are previous reports for bilateral hand extensor tendon involvement, to our knowledge there is no report in English literature regarding bilateral hands with small joint synovium presenting as rheumatoid arthritis. Therefore, the case that is presented in this report is unique...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29282397/swan-neck-deformity-mimicking-claw-hand-caused-by-arthritis-in-leprosy
#3
Hendra Gunawan, Nia Srie Haryati, Oki Suwarsa
Swan neck deformity is a hyperextension of the proximal interphalangeal (PIP) joints and flexion of the distal interphalangeal (DIP) joints. Claw hand is a hyperextension of the metacarpal joints and flexion of the PIP joints, accompanied by reduced motor strength. A 23-year-old female, who was released from leprosy treatment, presented with a bend of the second to fifth fingers of both hands. There was hyperextension of the PIP joints and flexion of the DIP joints from the second to fifth fingers of both hands, thickening of the ulnar nerves, and hypoesthesia without motor impairment of the fourth and fifth fingers of both hands...
September 2017: Case Reports in Dermatology
https://www.readbyqxmd.com/read/29242702/proliferative-synovitis-of-the-shoulder-bursae-is-a-key-feature-for-discriminating-elderly-onset-rheumatoid-arthritis-mimicking-polymyalgia-rheumatica-from-polymyalgia-rheumatica
#4
Takeshi Suzuki, Ryochi Yoshida, Yuka Hidaka, Yu Seri
Semiquantitative scoring for subacromial bursa (SAB), subdeltoid bursa (SDB), and subcoracoid bursa by both gray-scale (GS) and power Doppler (PD) ultrasonography was performed in 15 patients with polymyalgia rheumatica (PMR) (72.6 ± 7.7 years old) and 15 patients with elderly onset rheumatoid arthritis with PMR-like onset (pm-EORA) (70.7 ± 7.0 years old) before starting treatment. The GS grades of SAB were significantly higher in the shoulders with pm-EORA than in the shoulders with PMR. The GS and PD scores of SAB and the PD scores of SDB were significantly higher in pm-EORA than in PMR cases...
2017: Clinical Medicine Insights. Arthritis and Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29225245/oral-methotrexate-related-lymphoproliferative-disease-presenting-with-severe-osteonecrosis-of-the-jaw-a-case-report-and-literature-review
#5
Sachiko Furukawa, Kazunari Oobu, Masafumi Moriyama, Shintaro Kawano, Saori Sako, Jun-Nosuke Hayashida, Ryota Matsubara, Ken-Ichi Ogata, Tamotsu Kiyoshima, Seiji Nakamura
Long-term methotrexate (MTX) treatment can cause MTX-related lymphoproliferative disorder (MTX-LPD). We experienced a case of MTX-LPD that was associated with severe osteonecrosis of the jaw mimicking medication-related osteonecrosis of the jaw. The patient was an 81-year-old woman with rheumatoid arthritis (RA) who was treated with MTX and bisphosphonate. After 7 years, she was referred to our department for the assessment of giant ulcer and exposure of the alveolar bone of the left maxilla. Histopathological and immunological analyses confirmed a diagnosis of MTX-LPD...
December 8, 2017: Internal Medicine
https://www.readbyqxmd.com/read/29218754/cutaneous-leishmaniasis-mimicking-dactylitis-in-a-patient-with-rheumatoid-arthritis-treated-with-certolizumab
#6
J Herrerias-Moreno, V Expósito-Serrano, E Agut-Busquet, M Corbacho, E Sáez, J Luelmo
No abstract text is available yet for this article.
December 8, 2017: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/29181179/efficacy-of-bendamustine-on-thrombocytopenia-and-hemolytic-anemia-secondary-to-cd5-positive-b-cell-lymphoma-with-massive-splenomegaly-in-a-patient-with-rheumatoid-arthritis
#7
Yuzuru Hosoda, Hiroshi Hagino, Norihiko Hino, Toru Motokura
Chemotherapy for lymphoma may be avoided in the presence of coincident cytopenia. In case of immune cytopenia secondary to lymphoma, treatment of cytopenia is the same for primary cases, however, chemotherapy for lymphoma may be effective at the cost of severe hematological toxicity. The present study reports a complex case of thrombocytopenia and direct antiglobulin test-negative hemolytic anemia, thus mimicking Evans syndrome, secondary to cluster of differentiation 5-positive B-cell lymphoma with massive splenomegaly, in a patient suffering from rheumatoid arthritis for two decades...
November 2017: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/29166574/altered-tnf-%C3%AE-response-by-aconibal-%C3%A2-and-methotrexate-in-a-lipopolysaccharide-induced-setting-of-inflammatory-conditions-potential-on-a-synergistic-combination
#8
Gunhyuk Park, Seoung Hoon Lee, Ji-Ye Han, Dal-Seok Oh
ETHNOPHARMACOLOGICAL RELEVANCE: Aconitum carmichaelii (AC) is a common herbal medicine used as anti-inflammatory and analgesic agent in Eastern Asia. In Korea, a commercial processed AC (Aconibal(®)) is traditionally used to treat the symptoms of spondylosis deformans and rheumatic pain. AIM OF STUDY: Rheumatoid arthritis (RA) is systemic and auto-immune disease characterized by chronic inflammation. Methotrexate (MTX) is often the first-line therapy for RA. If MTX monotherapy is ineffective or RA is initially severe, adding a tumor necrosis factor (TNF)-α inhibitor to the treatment can be beneficial...
November 19, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/29164284/uncommon-observation-of-bifocal-giant-subchondral-cysts-in-the-hip-diagnostic-role-of-ct-arthrography-and-mri-with-pathological-correlation
#9
Pauline Gonzalez-Espino, Maïté Van Cauter, Louis Gossing, Christine C Galant, Souad Acid, Frederic E Lecouvet
Subchondral cysts (or geodes) are common in osteoarthritis (OA), usually in association with other typical signs, i.e., joint space narrowing, subchondral bone sclerosis, and osteophytosis. However, large lesions without the typical signs of OA or lesions located outside the weight-bearing areas are unusual and may be confused for other conditions, in particular, those of tumoral origin. We report the findings in a 48-year-old man who had been complaining of left buttock pain for 3 years, getting worse over the last year, and an evolutive limited range of motion of the hip...
November 21, 2017: Skeletal Radiology
https://www.readbyqxmd.com/read/29146737/rheumatic-disorders-associated-with-immune-checkpoint-inhibitors-in-patients-with-cancer-clinical-aspects-and-relationship-with-tumour-response-a-single-centre-prospective-cohort-study
#10
Marie Kostine, Léa Rouxel, Thomas Barnetche, Rémi Veillon, Florent Martin, Caroline Dutriaux, Léa Dousset, Anne Pham-Ledard, Sorilla Prey, Marie Beylot-Barry, Amaury Daste, Marine Gross-Goupil, Julie Lallier, Alain Ravaud, Edouard Forcade, Bernard Bannwarth, Marie-Elise Truchetet, Christophe Richez, Nadia Mehsen, Thierry Schaeverbeke
OBJECTIVES: To evaluate the prevalence and type of rheumatic immune-related adverse events (irAEs) in patients receiving immune checkpoint inhibitors (ICIs), as well as the correlation with tumour response. METHODS: This was a single-centre prospective observational study including all cancer patients receiving ICIs. The occurrence of irAEs and tumour response was assessed on a regular basis. Patients who experienced musculoskeletal symptoms were referred to the department of rheumatology for clinical evaluation and management...
November 16, 2017: Annals of the Rheumatic Diseases
https://www.readbyqxmd.com/read/29133662/a-tiny-tick-can-cause-a-big-health-problem
#11
Manuel John, M Raman, Keith Ryan
Ticks are tiny crawling bugs in the spider family that feed by sucking blood from animals. They are second only to mosquitoes as vectors of human disease, both infectious and toxic. Infected ticks spread over a hundred diseases, some of which are fatal if undetected. They spread the spirochete (which multiplies in the insect's gut) with a subsequent bite to the next host. We describe the only reported cases of peri ocular tick bite from India that presented to us within a span of 3 days and its management. Due suspicion and magnification of the lesions revealed the ticks which otherwise masqueraded as small skin tags/moles on gross examination...
November 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/29096690/tlr2-stimulation-impairs-anti-inflammatory-activity-of-m2-like-macrophages-generating-a-chimeric-m1-m2-phenotype
#12
Lilian Quero, Edveena Hanser, Tobias Manigold, André N Tiaden, Diego Kyburz
BACKGROUND: Toll-like receptors (TLRs) and macrophages play an important role in rheumatoid arthritis (RA). Currently, it is not clear whether inflammatory M1 or anti-inflammatory M2 predominate among the resident macrophages in the synovium. In the present study, we set out to investigate the impact of TLR stimulation on monocyte-derived M1 and M2 macrophage function and phenotype by mimicking the exposure to abundant TLR agonists as occurs in the context of RA. The response of macrophage subsets to TLR2 and TLR4 activation was evaluated on cluster of differentiation (CD) marker profile; cytokine secretion; gene expression; and NF-κB, interferon regulatory factors 3 and 7 (IRF3/7), and mitogen-activated protein kinase (MAPK) activation...
November 2, 2017: Arthritis Research & Therapy
https://www.readbyqxmd.com/read/29077233/death-effects-of-reveromycin-a-in-normal-and-disease-associated-cells-of-the-joint
#13
Haley Svrcina, Austin Greer, Seth Baker, Morgan Smith, Patricia Martinez, Nathan Granger, Natassja Thomas, Jaylin Miller, Ellen Steinke, Kelsey Davitt, Emily Sloane, Lauren Nugent, Ryan Sabo, Calli Williams, Mark A Lipton, Daniel Jones
Earlier work in our laboratory demonstrated that naturally occurring reveromycin A (Rev A) causes apoptosis in osteoclasts without accompanying necrosis. Rev A death effects in both normal and diseased joint cells were investigated in this study. 10 □M Rev A did not cause apoptosis nor necrosis in monolayer chondrocytes, even at pH 6.8, a pH mimicking that of an inflamed joint. In contrast, at the acidic pH Rev A did induce significant apoptosis (four-fold increase at 48 hours of treatment, p<0.005) in normal synoviocytes without accompanying necrosis...
October 27, 2017: Journal of Cellular Biochemistry
https://www.readbyqxmd.com/read/28982129/the-tyrosine-kinase-inhibitor-imatinib-mesylate-suppresses-uric-acid-crystal-induced-acute-gouty-arthritis-in-mice
#14
Laurent L Reber, Philipp Starkl, Bianca Balbino, Riccardo Sibilano, Nicolas Gaudenzio, Stephan Rogalla, Steven Sensarn, Dongmin Kang, Harini Raghu, Jeremy Sokolove, William H Robinson, Christopher H Contag, Mindy Tsai, Stephen J Galli
Gouty arthritis is caused by the deposition of monosodium urate (MSU) crystals in joints. Despite many treatment options for gout, there is a substantial need for alternative treatments for patients unresponsive to current therapies. Tyrosine kinase inhibitors have demonstrated therapeutic benefit in experimental models of antibody-dependent arthritis and in rheumatoid arthritis in humans, but to date, the potential effects of such inhibitors on gouty arthritis has not been evaluated. Here we demonstrate that treatment with the tyrosine kinase inhibitor imatinib mesylate (imatinib) can suppress inflammation induced by injection of MSU crystals into subcutaneous air pouches or into the ankle joint of wild type mice...
2017: PloS One
https://www.readbyqxmd.com/read/28963072/prostaglandin-e2-restrains-human-treg-cell-differentiation-via-e-prostanoid-receptor-2-protein-kinase-a-signaling
#15
Hui Li, Hai-Ying Chen, Wen-Xuan Liu, Xian-Xian Jia, Jing-Ge Zhang, Chun-Ling Ma, Xiao-Jing Zhang, Feng Yu, Bin Cong
Regulatory T cells (Treg cells) belong to a class of immunosuppressive cells that control the pathological changes of autoimmunity and inflammation. Prostaglandin E2 (PGE2) is a potent lipid mediator of immune inflammation including rheumatoid arthritis (RA) that exerts its effects via four subtypes of G-protein-coupled receptors (EP1-4). The ability of PGE2 to regulate human Treg differentiation has not yet been reported. In the current study, we investigated the effects of PGE2 on the differentiation of naïve T cells from healthy and RA patients into Treg cells and the intracellular signaling involved in this process in vitro...
September 28, 2017: Immunology Letters
https://www.readbyqxmd.com/read/28960309/pain-relieving-and-protective-effects-of-astragalus-hydroalcoholic-extract-in-rat-arthritis-models
#16
Mario Maresca, Laura Micheli, Lorenzo Cinci, Anna Rita Bilia, Carla Ghelardini, Lorenzo Di Cesare Mannelli
OBJECTIVES: The evaluation of the pharmacological profile of the dried 50% hydroalcoholic extract (50%HA) of Astragali radix in two different animal models of articular damage resembling osteoarthritis and rheumatoid arthritis. METHODS: Sodium monoiodoacetate (MIA) or complete Freund's adjuvant (CFA) was intra-articular injected (day 0) in the rat tibiotarsal joint to induce damages mimicking osteoarthritis or rheumatoid arthritis. Pain measurements (responses to non-noxious and noxious stimuli, spontaneous pain, articular pain) were assessed on days 7 and 14...
September 29, 2017: Journal of Pharmacy and Pharmacology
https://www.readbyqxmd.com/read/28901253/bacterial-toxins-a-hope-towards-angiogenic-ailments
#17
Rekha Khandia, Ashok Kumar Munjal, Kuldeep Dhama, Yashpal Singh Malik
Angiogenesis is a vital physiological process essential for growth and maintenance of the body. It plays an important role during embryonic development and generally absent in adults with some exceptions like during wound repair and menstrual cycle in women. Excess as well as deficiency in angiogenesis, result in pathological conditions. It is a tightly regulated process; rely on cascade of several molecular signalling pathways involving many effectors like VEGF, FGF, PDGF, IGF etc. Excessive angiogenesis is associated with disorders like tumor, atherosclerosis, rheumatoid arthritis, diabetic retinopathy, endometriosis, psoriasis, adiposity...
September 11, 2017: Current Drug Metabolism
https://www.readbyqxmd.com/read/28681371/breast-cancer-in-patients-of-rheumatoid-arthritis-with-methotrexate-therapy-mimicking-histopathological-changes-after-neoadjuvant-chemotherapy
#18
Nobue Kumaki, Chizuko Okamatsu, Yutaka Tokuda, Naoya Nakamura
Two breast cancer patients with a history of treatment for long-term rheumatoid arthritis (RA) had histological findings similar to histological changes seen in resected mammary gland specimens following neoadjuvant chemotherapy (NAC). The first patient was a 64-year-old woman who visited our hospital after feeling a lump in her left breast. The second patient was a 68-year-old woman who visited our hospital for an indentation in her left nipple. They were diagnosed with breast cancer following detailed examinations and underwent mastectomy...
July 20, 2017: Tokai Journal of Experimental and Clinical Medicine
https://www.readbyqxmd.com/read/28589069/looks-can-be-deceiving-a-case-report-on-multicentric-reticulohistiocytosis-successfully-treated-with-rituximab
#19
Khin Lim, Jason D'Souza, Jonathan B Vasquez, Sujatha Vuyyuru
Multicentric reticulohistiocytosis (MRH) is an idiopathic multisystemic inflammatory disease characterized by symmetric erosive polyarthritis and typical papulonodular skin lesions. MRH can be associated with autoimmune diseases, malignancy, mycobacterial infections, and hyperlipidemia, and it is important to consider appropriate screening in this population. There is no specific diagnostic laboratory test for MRH. The gold standard for diagnosis is skin or synovial biopsy, which shows characteristic multinucleated non-Langerhans giant cells and ground glass eosinophilic cytoplasm...
May 3, 2017: Curēus
https://www.readbyqxmd.com/read/28545554/whipple-s-disease-mimicking-rheumatoid-arthritis-can-cause-misdiagnosis-and-treatment-failure
#20
Cornelia Glaser, Siegbert Rieg, Thorsten Wiech, Christine Scholz, Dominique Endres, Oliver Stich, Peter Hasselblatt, Walter Geißdörfer, Christian Bogdan, Annerose Serr, Georg Häcker, Reinhard E Voll, Jens Thiel, Nils Venhoff
BACKGROUND: Whipple's disease, a rare chronic infectious disorder caused by Tropheryma whipplei, may present with predominant joint manifestations mimicking rheumatoid arthritis (RA). METHODS: A retrospective single-center cohort study of seven patients was performed. Clinical symptoms were assessed by review of medical charts and Whipple's disease was diagnosed by periodic-acid-Schiff-stain and/or Tropheryma whipplei-specific polymerase-chain-reaction. RESULTS: Median age at disease onset was 54 years, six patients were male...
May 25, 2017: Orphanet Journal of Rare Diseases
keyword
keyword
48230
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"