Juan Zhao, Yu Chen, Zhifen Ding, Yaru Zhou, Ruiqing Bi, Ziting Qin, Lei Yang, Peng Sun, Qiping Sun, Guang Chen, Daiyuan Sun, Xianya Jiang, Lu Zheng, Xiao-Lin Chen, Hu Wan, Guanghui Wang, Qiang Li, Huailong Teng, Guotian Li
Plant diseases cause enormous economic losses in agriculture and threaten global food security, and application of agrochemicals is an important means to control crop diseases. Thus, exploring disease-resistant mechanisms and synthesis of highly bioactive agrochemicals are of great importance. Here, we showed that propranolol, a phosphatidate phosphatase (Pah) inhibitor, effectively suppressed fungal growth, sporulation, sexual reproduction, and plant infection on diverse plants. The MoPah1 enzyme activity of the rice blast fungus Magnaporthe oryzae was inhibited by propranolol...
August 30, 2023: Plant communications