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https://www.readbyqxmd.com/read/29244264/personality-traits-and-anxiety-and-depressive-disorders-in-patients-with-medication-overuse-headache-versus-episodic-migraine
#1
Nima Mohseni, Mansooreh Togha, Seyed Masoud Arzaghi, Sepideh Nekooie, Mehrnaz Fallah Tafti, Farzad Fatehi
Objective: An episodic migraine (EM) may lead to medication-overuse headache (MOH), an abnormal behavioral pattern of noncompliance. Anxiety disorders, mood disorders, and disorders caused by psychoactive substances other than analgesics all have been reported with MOH at higher rates than with EM. The objective of this study was to evaluate the relationships between personality traits and anxiety and depressive disorders and headache type. Methods: In this cross-sectional study, 55 patients with EM and 50 patients with MOH were recruited from were recruited from 2 university hospital clinics in Tehran, Iran, from January 2013 to November 2015...
December 14, 2017: Primary Care Companion to CNS Disorders
https://www.readbyqxmd.com/read/29242843/systemic-oxidoreductive-balance-and-vascular-function-in-individuals-without-clinical-manifestation-of-atherosclerosis
#2
Marcin Majer, Daniel Gackowski, Rafał Różalski, Agnieszka Siomek-Górecka, Ryszard Oliński, Jacek Budzyński
Introduction: Endothelial dysfunction is recognized as the earliest disorder in the development of atherosclerosis, in the pathogenesis of which oxidative stress plays a crucial role. The aim of this study was to determine the relationships between non-invasive parameters of vascular dysfunction and oxidative stress. Material and methods: Forty-eight individuals without clinical manifestation of atherosclerosis were studied. The plasma concentrations of the following were determined in all 48 subjects: retinol, ascorbic acid, α-tocopherol and uric acid, as well as the products of oxidative DNA damage repair: 8-oxo-7,8-dihydro-2'-deoxyguanosine (8-oxodG) in blood leukocytes and urine, and 8-oxo-7,8-dihydroguanine (8-oxoGua) in urine...
2017: Archives of Medical Sciences. Atherosclerotic Diseases
https://www.readbyqxmd.com/read/29241996/fracture-related-mortality-in-southern-sweden-a-multiple-cause-of-death-analysis-1998-2014
#3
Aliasghar A Kiadaliri, Björn E Rosengren, Martin Englund
PURPOSE: To assess fracture-related mortality among adults (aged ≥20years) in southern Sweden using multiple causes of death approach. METHODS: All death certificates (n=201 488) in adults recorded in the region of Skåne from 1998 to 2014 were examined. We identified fracture-related deaths and computed mortality rates by sex, age group, and fracture site. Temporal trends were evaluated using joinpoint regression and associated causes were identified by age- and sex-adjusted observed/expected ratios...
December 9, 2017: Injury
https://www.readbyqxmd.com/read/29228820/associations-between-depressive-symptomatology-and-neurocognitive-impairment-in-hiv-aids
#4
Sarah Tymchuk, Daniela Gomez, Noshin Koenig, M John Gill, Esther Fujiwara, Christopher Power
OBJECTIVE: Mood disorders and neurocognitive impairments are debilitating conditions among patients with HIV/AIDS. How these comorbidities interact and their relationships to systemic factors remain uncertain. Herein, we investigated factors contributing to depressive symptomatology (DS) in a prospective cohort of patients with HIV/AIDS in active care that included neuropsychological assessment. METHODS: Among patients with HIV/AIDS receiving combination antiretroviral therapy (cART) and ongoing clinical assessments including measures of sleep, health-related quality of life (HQoL), neuropsychological testing, and mood evaluation (Patient Health Questionnaire-9 [PHQ-9]) were performed...
January 1, 2017: Canadian Journal of Psychiatry. Revue Canadienne de Psychiatrie
https://www.readbyqxmd.com/read/29218870/loss-of-function-of-neuroplasticity-related-genes-confers-risk-for-human-neurodevelopmental-disorders
#5
Milo R Smith, Benjamin S Glicksberg, Li Li, Rong Chen, Hirofumi Morishita, Joel T Dudley
High and increasing prevalence of neurodevelopmental disorders place enormous personal and economic burdens on society. Given the growing realization that the roots of neurodevelopmental disorders often lie in early childhood, there is an urgent need to identify childhood risk factors. Neurodevelopment is marked by periods of heightened experience-dependent neuroplasticity wherein neural circuitry is optimized by the environment. If these critical periods are disrupted, development of normal brain function can be permanently altered, leading to neurodevelopmental disorders...
2018: Pacific Symposium on Biocomputing
https://www.readbyqxmd.com/read/29217452/specific-agreement-on-ordinal-and-multiple-nominal-outcomes-can-be-calculated-for-more-than-two-raters
#6
Henrica C W de Vet, Margriet G Mullender, Iris Eekhout
OBJECTIVE: The concept of specific agreement has been proposed for dichotomous outcomes for two and more raters. We aim to extend this concept for variables with more than two ordinal or nominal categories and more than two raters. STUDY DESIGN AND SETTING: We used two data sets: 4 plastic surgeons classifying photographs after breast reconstruction on a 5 point ordinal scale; and 6 raters classifying psychiatric patients into 5 diagnostic categories. For m raters, all (i...
December 4, 2017: Journal of Clinical Epidemiology
https://www.readbyqxmd.com/read/29209501/association-among-self-compassion-childhood-invalidation-and-borderline-personality-disorder-symptomatology-in-a-singaporean-sample
#7
Shian-Ling Keng, Yun Yi Wong
Background: Linehan's biosocial theory posits that parental invalidation during childhood plays a role in the development of borderline personality disorder symptoms later in life. However, little research has examined components of the biosocial model in an Asian context, and variables that may influence the relationship between childhood invalidation and borderline symptoms. Self-compassion is increasingly regarded as an adaptive way to regulate one's emotions and to relate to oneself, and may serve to moderate the association between invalidation and borderline symptoms...
2017: Borderline Personality Disorder and Emotion Dysregulation
https://www.readbyqxmd.com/read/29209434/vitamin-d-in-the-prevention-prediction-and-treatment-of-neurodegenerative-and-neuroinflammatory-diseases
#8
REVIEW
Priscilla Koduah, Friedemann Paul, Jan-Markus Dörr
Vitamin D research has gained increased attention in recent times due to its roles beyond bone health and calcium homeostasis, such as immunomodulation. In some parts of the brain and on immune cells, vitamin D hydroxylating enzymes and its receptors are located. Epidemiological evidence demonstrates that deficiency of Vitamin D is relevant for disease risk and course in multiple sclerosis (MS) and presumably also in neuromyelitis optica spectrum disorders (NMOSD), Parkinson's disease (PD), and Alzheimer's disease (AD)...
December 2017: EPMA Journal
https://www.readbyqxmd.com/read/29202131/multifunctional-system-for-observing-measuring-and-analyzing-stimulation-evoked-neurochemical-signaling
#9
Christopher J Kimble, Joshua B Boesche, Diane R Eaker, Kenneth R Kressin, James K Trevathan, Seungleal Paek, Anders J Asp, Malcolm B McIntosh, J Luis Lujan
The ability to measure neurotransmitter activity using implanted electrochemical sensors offers researchers a potent technique for analyzing neural activity across specific neural circuitry. We have developed a wirelessly controlled device, WINCS Harmoni, to observe and measure neurotransmitter dynamics at up to four separate sensors, with high temporal and spatial resolution. WINCS Harmoni also incorporates a versatile neurostimulator that can be synchronized with electrochemical recording. The WINCS Harmoni platform is thus optimally suited for probing the neurochemical effects of neurostimulation, and may in turn enable the development of personalized therapies for multiple brain disorders...
May 2017: IEEE International Symposium on Medical Measurements and Applications: Proceedings
https://www.readbyqxmd.com/read/29197109/prospective-test-of-the-developmental-propensity-model-of-antisocial-behavior-from-childhood-and-adolescence-into-early-adulthood
#10
Benjamin B Lahey, Quetzal A Class, David H Zald, Paul J Rathouz, Brooks Applegate, Irwin D Waldman
BACKGROUND: The developmental propensity model of antisocial behavior posits that several dispositional characteristics of children transact with the environment to influence the likelihood of learning antisocial behavior across development. Specifically, greater dispositional negative emotionality, greater daring, and lower prosociality-operationally, the inverse of callousness- and lower cognitive abilities are each predicted to increase risk for developing antisocial behavior. METHODS: Prospective tests of key predictions derived from the model were conducted in a high-risk sample of 499 twins who were assessed on dispositions at 10-17 years of age and assessed for antisocial personality disorder (APD) symptoms at 22-31 years of age...
December 2, 2017: Journal of Child Psychology and Psychiatry, and Allied Disciplines
https://www.readbyqxmd.com/read/29195773/cognitive-deficits-in-bipolar-disorders-implications-for-emotion
#11
REVIEW
Isabela M M Lima, Andrew D Peckham, Sheri L Johnson
Prominent cognitive deficits have been documented in bipolar disorder, and multiple studies suggest that these deficits can be observed among non-affected first-degree relatives of those with bipolar disorder. Although there is variability in the degree of cognitive deficits, these deficits are robustly relevant for functional outcomes. A separate literature documents clear difficulties in emotionality, emotion regulation, and emotion-relevant impulsivity within bipolar disorder, and demonstrates that these emotion-relevant variables are also central to outcome...
November 21, 2017: Clinical Psychology Review
https://www.readbyqxmd.com/read/29192688/fluoridation-and-attention-deficit-hyperactivity-disorder-a-critique-of-malin-and-till-2015
#12
K W Perrott
A recent ecological study found a statistically significant association of attention deficit hyperactivity disorder (ADHD) prevalence in youth with exposure to fluoride in fluoridated water. However, it included only household income as a possible covariate. In contrast another study found a significant association of ADHD prevalence with residential altitude. A multiple regression analysis including water fluoridation extent, mean US state elevation and a number of possibly important social factors as covariates showed statistically significant associations of ADHD prevalence in 2011 with altitude and per capita personal income in 2009...
December 1, 2017: British Dental Journal
https://www.readbyqxmd.com/read/29183177/low-apgar-scores-in-term-newborns-and-long-term-gastro-intestinal-morbidity-a-population-based-cohort-study-with-up-to-18%C3%A2-years-of-follow-up
#13
Noa Leybovitz-Haleluya, Tamar Wainstock, Eyal Sheiner, Idit Segal, Daniella Landau, Asnat Walfisch
INTRODUCTION: Low Apgar scores (< 7) measured at age 5 minutes can predict short-term infant morbidity and mortality. Although an association exists between low Apgar scores and neuropsychological disorders, other childhood disorders were not thoroughly studied. We aimed to study the possible association between low 5-minute Apgar scores in term newborns and their long-term childhood gastrointestinal (GI) morbidity. METHODS: A population based cohort analysis was performed comparing total and different subtypes of GI related pediatric hospitalizations among newborns with normal (≥ 7) and low (< 7) 5-minute Apgar scores...
November 28, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29182033/influence-of-physical-activity-on-the-health-related-quality-of-life-of-young-adults-with-and-without-autism-spectrum-disorder
#14
Jessica Hamm, Joonkoo Yun
BACKGROUND: Health-related quality of life constructs has been used to understand the multiple dimensions (i.e., physical health, psychological, environment and social relationships) that affect a person's health status. In order to improve health-related quality of life for young adults, it is important to understand the factors that influence each dimension. The purpose of this paper was to examine the influence of the presence of autism spectrum disorder and physical activity on the multiple domains of health-related quality of life for young adults...
November 28, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/29180054/-a-therapeutic-education-program-for-parents-of-children-with-asd-preliminary-results-about-the-effectiveness-of-the-etap-program
#15
C Derguy, M Poumeyreau, S Pingault, K M'bailara
Autism Spectrum Disorders (ASD) are characterized by particularities of cognitive and socio-adaptive functioning. Daily, they require specific interventions for the disabled person as well as support for parents who often report deterioration in their physical and mental health. To this end, the latest Autism Plan 2013-2017 highlights the need "to help families to be present and active alongside their loved ones, to avoid situations of exhaustion and stress and to enable them to play their role fully in the long term"...
November 24, 2017: L'Encéphale
https://www.readbyqxmd.com/read/29179936/clinical-relevance-of-appraisals-of-persistent-psychotic-experiences-in-people-with-and-without-a-need-for-care-an-experimental-study
#16
Emmanuelle Peters, Thomas Ward, Mike Jackson, Peter Woodruff, Craig Morgan, Philip McGuire, Philippa A Garety
BACKGROUND: Cognitive models of psychosis propose that appraisals (ie, the interpretation and meaning attributed to experiences) are central to the transition from anomalous experiences to psychotic symptoms. In the Unusual Experiences Enquiry (UNIQUE) study, we investigated the role of appraisals by comparing individuals with persistent psychotic experiences without a need for care with patients and people without psychotic experiences. METHOD: Eligible participants were patients with diagnosed psychotic disorders (clinical group) and adults in the general population with persistent psychotic experiences (non-clinical group) and without psychotic experiences (controls)...
December 2017: Lancet Psychiatry
https://www.readbyqxmd.com/read/29179258/increased-risk-of-autoimmune-disorders-in-infertile-men-analysis-of-us-claims-data
#17
W D Brubaker, S Li, L C Baker, M L Eisenberg
Aberrations in reproductive fitness may be a harbinger of medical diseases in men. Existing data suggest that female infertility is associated with autoimmune disorders; however, this has not been examined in men. As immune surveillance and hormonal factors can impact male fertility and autoimmunity, we sought to determine the association between male infertility and incident autoimmune disorders. We analyzed subjects from the Truven Health MarketScan claims database from 2001 to 2008. Infertile men were identified through diagnosis and treatment codes...
November 27, 2017: Andrology
https://www.readbyqxmd.com/read/29178935/estimating-annual-prevalence-of-depression-and-anxiety-disorder-in-multiple-sclerosis-using-administrative-data
#18
Ruth Ann Marrie, Randy Walld, James M Bolton, Jitender Sareen, John R Walker, Scott B Patten, Alexander Singer, Lisa M Lix, Carol A Hitchon, Renée El-Gabalawy, Alan Katz, John D Fisk, Charles N Bernstein
OBJECTIVE: Researchers have developed case definitions to estimate incidence and lifetime prevalence of depression and anxiety disorders in multiple sclerosis (MS) using administrative data. For policymakers however, the prevalence of a disease requiring ongoing treatment during a given period such as annual period prevalence may be more relevant for decision-making. We tested a case definition for annual period prevalence of depression and anxiety disorders in MS using administrative data...
November 25, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/29176959/gender-specific-relationship-between-obesity-and-major-depression
#19
Li Li, Barbara A Gower, Richard C Shelton, Xiaoyan Wu
Objective: Prior research suggests a bidirectional relationship between obesity and major depressive disorder (MDD), but the results have been heterogeneous. Differences between males and females in the association of MDD with obesity may contribute to inconsistent results. Thus, this study was designed to determine whether sex has a differential effect on the relationship between MDD and obesity, and to explore the potential mechanisms. Methods: All participants were diagnosed with MDD, and depression severity was measured using the 17-item Hamilton Depression Rating Scale...
2017: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/29174666/combining-ecological-momentary-assessment-with-objective-ambulatory-measures-of-behavior-and-physiology-in-substance-use-research
#20
Jeremiah W Bertz, David H Epstein, Kenzie L Preston
Whereas substance-use researchers have long combined self-report with objective measures of behavior and physiology inside the laboratory, developments in mobile/wearable electronic technology are increasingly allowing for the collection of both subjective and objective information in participants' daily lives. For self-report, ecological momentary assessment (EMA), as implemented on contemporary smartphones or personal digital assistants, can provide researchers with near-real-time information on participants' behavior and mood in their natural environments...
November 16, 2017: Addictive Behaviors
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