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https://www.readbyqxmd.com/read/29469663/a-neuroscience-oriented-research-approach-to-borderline-personality-disorder
#1
Barbara Stanley, M Mercedes Perez-Rodriguez, Christa Labouliere, Steven Roose
Traditionally, the study of personality disorders had been based on psychoanalytic or behavioral models. Over the past two decades, there has been an emerging neuroscience model of borderline personality disorder (BPD) grounded in the concept of BPD as a condition in which dysfunctional neural circuits underlie its pathological dimensions, some of which include emotion dysregulation (broadly encompassing affective instability, negative affectivity, and hyperarousal), abnormal interpersonal functioning, and impulsive aggression...
February 22, 2018: Journal of Personality Disorders
https://www.readbyqxmd.com/read/29466805/personality-disorder-and-alcohol-use-disorder-an-overview
#2
Giles Newton-Howes, James Foulds
BACKGROUND: Clinically, personality disorder (PD) commonly coexists with alcohol use disorder (AUD), although within mainstream mental health services both of these mental disorders are routinely overlooked. Despite a rich literature examining the interactions between AUD and personality functioning, personality traits, and PD, there remains conflicting evidence as to the degree of association and impact of one on the other. METHODS: A narrative review and a synthesis of the literature were done...
February 21, 2018: Psychopathology
https://www.readbyqxmd.com/read/29455340/an-international-clinical-study-of-ability-and-disability-in-adhd-using-the-who-icf-framework
#3
Soheil Mahdi, Nadia Ronzano, Ane Knüppel, José Carlos Dias, Ayman Albdah, Lin Chien-Ho, Omar Almodayfer, Annet Bluschke, Sunil Karande, Huei-Lin Huang, Hanna Christiansen, Mats Granlund, Petrus J de Vries, David Coghill, Rosemary Tannock, Luis Rohde, Sven Bölte
This is the fourth and final study designed to develop International Classification of Functioning, Disability and Health (ICF, and children and youth version, ICF-CY) core sets for attention-deficit hyperactivity disorder (ADHD). To investigate aspects of functioning and environment of individuals with ADHD as documented by the ICF-CY in clinical practice settings. An international cross-sectional multi-centre study was applied, involving nine units from eight countries: Denmark, Germany, India, Italy, Portugal, Saudi Arabia, Sweden and Taiwan...
February 17, 2018: European Child & Adolescent Psychiatry
https://www.readbyqxmd.com/read/29447177/physician-prescribing-of-opioid-agonist-treatments-in-provincial-correctional-facilities-in-ontario-canada-a-survey
#4
Fiona G Kouyoumdjian, Alexandra Patel, Matthew J To, Lori Kiefer, Leonora Regenstreif
BACKGROUND: Substance use and substance use disorders are common in people who experience detention or incarceration in Canada, and opioid agonist treatment (OAT) may reduce the harms associated with substance use disorders. We aimed to define current physician practice in provincial correctional facilities in Ontario with respect to prescribing OAT and to identify potential barriers and facilitators to prescribing OAT. METHODS: We invited all physicians practicing in the 26 provincial correctional facilities for adults in Ontario to participate in an online survey...
2018: PloS One
https://www.readbyqxmd.com/read/29435179/identifying-characteristic-mirnas-genes-and-risk-pathways-of-multiple-sclerosis-based-on-bioinformatics-analysis
#5
Deling Luo, Jin Fu
Multiple sclerosis is a chronic autoimmune disorder of the central nervous system. In MS, the genetic susceptibility is high and currently there is no effective treatment. MicroRNA, a small non-coding RNA, plays a vital role in immune responses. Aberrant or dysfunctional miRNAs may cause several diseases, including MS, thus miRNAs and miRNA related genes may be therapeutic weapons against MS. Here, we identified 21 miRNAs in peripheral blood mono-nuclear cells from over 600 persons, including healthy controls...
January 12, 2018: Oncotarget
https://www.readbyqxmd.com/read/29432463/beyond-factor-analysis-multidimensionality-and-the-parkinson-s-disease-sleep-scale-revised
#6
Maria E Pushpanathan, Andrea M Loftus, Natalie Gasson, Meghan G Thomas, Caitlin F Timms, Michelle Olaithe, Romola S Bucks
Many studies have sought to describe the relationship between sleep disturbance and cognition in Parkinson's disease (PD). The Parkinson's Disease Sleep Scale (PDSS) and its variants (the Parkinson's disease Sleep Scale-Revised; PDSS-R, and the Parkinson's Disease Sleep Scale-2; PDSS-2) quantify a range of symptoms impacting sleep in only 15 items. However, data from these scales may be problematic as included items have considerable conceptual breadth, and there may be overlap in the constructs assessed. Multidimensional measurement models, accounting for the tendency for items to measure multiple constructs, may be useful more accurately to model variance than traditional confirmatory factor analysis...
2018: PloS One
https://www.readbyqxmd.com/read/29427131/eosinophilic-esophagitis-through-the-flexible-endoscope-and-the-lens-of-a-photographer-in-the-amazon
#7
REVIEW
Amal Assa'ad
Eosinophilic esophagitis (EoE) is a disorder that has been identified recently, thus knowledge about it, its pathogenesis, and potential etiologies has spread in an era where the medical community and the public are receiving the information and discussing it as it appears in the medical literature. Because physiology, pathology, and pathophysiology are difficult to explain in layman terms, the author has used photographs taken in remote areas of the Amazon to create visual similes within a narrative that brings the scientific and medical concepts of the knowledge on EoE to a level that allows both medical and non-medical persons to grasp and discuss their significance...
February 9, 2018: Clinical Reviews in Allergy & Immunology
https://www.readbyqxmd.com/read/29426814/exploring-the-specific-needs-of-persons-with-multiple-sclerosis-for-mhealth-solutions-for-physical-activity-mixed-methods-study
#8
Guido Giunti, Jan Kool, Octavio Rivera Romero, Enrique Dorronzoro Zubiete
BACKGROUND: Multiple sclerosis (MS) is one of the world's most common neurologic disorders, with symptoms such as fatigue, cognitive problems, and issues with mobility. Evidence suggests that physical activity (PA) helps people with MS reduce fatigue and improve quality of life. The use of mobile technologies for health has grown in recent years with little involvement from relevant stakeholders. User-centered design (UCD) is a design philosophy with the goal of creating solutions specific to the needs and tasks of the intended users...
February 9, 2018: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/29424787/major-depressive-disorder-longitudinal-analysis-of-impact-on-clinical-and-behavioural-outcomes-in-uganda
#9
Eugene Kinyanda, Jonathan Levin, Noeline Nakasujja, Harriet Birabwa, Juliet Nakku, Richard Mpango, Heiner Grosskurth, Soraya Seedat, Ricardo Araya, Maryam Shahmanesh, Vikram Patel
BACKGROUND: There is still wide variability in HIV disease course and other HIV related outcomes, attributable in part to psychosocial factors such as major depressive disorder (MDD), a subject that has received little attention in sub-Saharan Africa. METHODS: Using a longitudinal cohort of 1099 HIV positive antiretroviral therapy (ART) naïve persons, we investigated the impact of MDD on four HIV related negative outcome domains in Uganda. MDD was assessed using a Diagnostic Statistical Manual IV based tool...
February 7, 2018: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/29421343/applications-of-virtual-reality-in-individuals-with-alcohol-misuse-a-systematic-review
#10
REVIEW
Alexandra Ghiţă, José Gutiérrez-Maldonado
BACKGROUND: Alcohol use and misuse have been intensively studied, due to their negative consequences in the general population. Evidence-based literature emphasizes that alcohol craving plays a crucial role in the development and maintenance of alcohol-drinking patterns. Many individuals develop Alcohol Use Disorders (AUD); significantly, after treatment many also experience relapses, in which alcohol craving has been repeatedly implicated. Cue-exposure therapy (CET) has been widely used in the treatment of alcohol misuse, but the results are inconsistent...
February 1, 2018: Addictive Behaviors
https://www.readbyqxmd.com/read/29419677/risk-of-major-comorbidities-among-workers-with-hemophilia-a-14-year-population-based-study
#11
Wei-Min Chu, Hsin-En Ho, Jiaan-Der Wang, Wei-Cheng Chan, Yi-Sheng Liou, Wen-Chao Ho, Sung-Yuan Hu, Yu-Tse Tsan
Multiple comorbidities, especially musculoskeletal dysfunction and cerebrovascular disease, remain barriers to normal social participation among persons with hemophilia (PWH). However, the relative health effects of such comorbidities on workers with hemophilia have seldom been explored. In this study, we investigated the incidence of comorbidities and their risk factors among workers with hemophilia.The study compared the incidence and risk factors of the major comorbidities of 411 workers with hemophilia enrolled in Taiwan's National Health Insurance Research Database between 1997 and 2010 with an age- and sex-matched general population...
February 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29417307/caregiving-for-relatives-with-psychiatric-disorders-vs-co-occurring-psychiatric-and-substance-use-disorders
#12
Travis Labrum
Despite the high comorbidity of psychiatric and substance use disorders, extremely little research has examined the experience of caregiving for relatives with co-occurring psychiatric and substance use disorders (COD). The primary objective of the present article is to identify characteristics pertaining to care recipients, family caregivers, and the experience of providing caregiving associated with care recipients having COD vs. only having psychiatric disorders (PD). A U.S. community recruited sample of 1394 family caregivers of persons with COD or PD was employed...
February 8, 2018: Psychiatric Quarterly
https://www.readbyqxmd.com/read/29416838/investigating-the-role-of-interpersonal-sensitivity-anger-and-perfectionism-in-social-anxiety
#13
Youkhabeh Mohammadian, Behzad Mahaki, Mahmoud Dehghani, Mohammadkazem Atef Vahid, Fahimeh Fathali Lavasani
Background: The investigation of personality characteristics and emotional experiences of the people suffering from anxiety disorders is one of the most important issues which are considered by researchers and clinicians. Perfectionism, sensitivity to interpersonal rejection, and anger are personality traits related to social anxiety. In social anxiety disorder, it has also been focused on anger as a personality characteristic and as an emotional condition. The main purpose of this work is to investigate the role of these variables in predicting social anxiety among a nonclinical group of Iranian students...
2018: International Journal of Preventive Medicine
https://www.readbyqxmd.com/read/29415870/use-of-primary-healthcare-for-persons-with-epilepsy
#14
Dorte Rytter, Claus Høstrup Vestergaard, Mogens Vestergaard, Jakob Christensen, Bodil Hammer Bech
INTRODUCTION: In Denmark, care and treatment related to epilepsy primarily takes place at specialized hospital departments (neurology and pediatrics). The general practitioner (GP) in contrast is the primary contact and acts as a gatekeeper to the healthcare system for other disorders. The aim of the present study was to describe the utilization of services provided by the GP for children with epilepsy before and after diagnosis of epilepsy and to compare it with that of children without epilepsy...
February 4, 2018: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29415619/is-parkinson-s-disease-a-neurodevelopmental-disorder-and-will-brain-organoids-help-us-to-understand-it
#15
Jens Christian Schwamborn
Parkinson's disease is the second most common neurodegenerative disorder after Alzheimer's disease. The incidence of PD cases increases with age, accordingly classically PD is considered to be an age associated neurodegenerative disease. In this review the hypothesis that PD is actually a neurodevelopmental disorder that is compensated for long time, will be discussed. However, patients who suffer from Parkinson's disease typically do not show symptoms early in their live. This implies that, if the hypothesis that PD has a significant neurodevelopmental component is correct, the developmental defects are compensated for long time...
February 7, 2018: Stem Cells and Development
https://www.readbyqxmd.com/read/29414487/following-the-moving-and-changing-attachments-and-assemblages-of-addiction-applying-the-actor-network-approach-to-autobiographies
#16
Jukka Törrönen, Christoffer Tigerstedt
The article applies actor network theory (ANT) to autobiographical data on alcohol dependence to explore what ANT can offer to the analysis of 'addiction stories'. By defining 'addiction' as a relational achievement, as the effect of elements acting together as a configuration of human and non-human actors, the article demonstrates how the moving and changing attachments of addiction can be dynamically analyzed with concepts of 'assemblage', 'mediator', 'tendency', 'translation', 'trajectory', 'immutable mobile', 'fluid' and 'bush fire'...
January 30, 2018: International Journal on Drug Policy
https://www.readbyqxmd.com/read/29408593/acute-compartment-syndrome-as-a-complication-of-the-use-of-intraoperative-neuromonitoring-needle-electrodes
#17
Ilyas M Eli, Nicholas T Gamboa, Jian Guan, Philipp Taussky
BACKGROUND: The use of intraoperative neurophysiologic monitoring (IOM) has become commonplace in many neurosurgical procedures as a tool to reduce the risk of complications through the early identification of reversible neurologic compromise. Although complications related to IOM itself are exceedingly rare, recognizing their clinical presentation in the postoperative neurosurgical patient is essential for the early identification and implementation of appropriate treatment. CASE DESCRIPTION: The authors present a case report of a patient who developed postoperative acute compartment syndrome in the right arm after placement of neuromonitoring needles for routine IOM during endovascular treatment of a left internal carotid artery aneurysm...
February 3, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29404926/synergistical-action-of-the-%C3%AE-2-adrenoceptor-and-fatty-acid-binding-protein-2-polymorphisms-on-the-loss-of-glomerular-filtration-rate-in-chinese-patients-with-type-2-diabetic-nephropathy
#18
Tao Wang, Yan Zhang, Ning Wang, Qiong Liu, ZeKai Wang, Bing Liu, Kai Niu
PURPOSE: Since altered sympathetic nerve activity and insulin resistance are implicated in the pathogenesis of type 2 diabetic nephropathy, we investigated the effect of polymorphic Arg16Gly and Gln27Glu in the β2 adrenoceptor gene and Ala54Thr in the fatty acid binding protein 2 gene on the estimated glomerular filtration rate (eGFR) in Chinese patients with the above disease. METHODS: A total of 552 diabetic subjects recruited from annual health examinations were studied...
February 5, 2018: International Urology and Nephrology
https://www.readbyqxmd.com/read/29400677/male-and-female-opinions-about-orthotic-devices-of-the-lower-limb-a-multicentre-observational-study-in-patients-with-central-neurological-movement-disorders
#19
Eva Swinnen, Nina Lefeber, Amber Werbrouck, Yelena Gesthuizen, Lisa Ceulemans, Sofie Christiaens, Lise De Wael, Ronald Buyl, Stephan Ilsbroukx, Johan Van Nieuwenhoven, Marc Michielsen, Christophe Lafosse, Eric Kerckhofs
BACKGROUND AND OBJECTIVE: Because user-satisfaction and acceptance may partly determine the grade of compliance to an orthotic device (OD), the aim of this multicentre observational study was to inquire the reasons for acceptance and the user-satisfaction of an OD of the lower limb in male and female central neurological movement disorders (CNMD) patients. METHODS: Persons with CNMD having at least one prescribed OD of the lower limb were included. Two questionnaires were used: the MIRAD-ACCORT-II (reasons for acceptance) and a modified version of the D-QUEST 2...
2018: NeuroRehabilitation
https://www.readbyqxmd.com/read/29395874/association-between-bipolar-disorder-and-subsequent-traumatic-brain-injury-in-patients-who-received-inpatient-treatment
#20
Mei-Feng Huang, Chen-Hsiang Su, Hung-Pin Tu, Tai-Ling Liu, Chih-Lung Lin, Cheng-Sheng Chen, Yi-Chun Yeh
Mental disorders may confer a high risk of traumatic brain injury, but only rare studies have investigated mood disorders. This nationwide cohort study compared the risk of traumatic brain injury in patients with and without bipolar disorder. We compared 1017 patients with bipolar disorder who received inpatient treatment and 9080 compared patients. The annual incidence rate of traumatic brain injury was calculated as the number of new cases divided by the total number of person-years in the available records...
January 10, 2018: Psychiatry Research
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