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https://www.readbyqxmd.com/read/28515272/racial-disparities-in-neurologic-health-care-access-and-utilization-in-the-united-states
#1
Altaf Saadi, David U Himmelstein, Steffie Woolhandler, Nicte I Mejia
OBJECTIVE: To evaluate racial and ethnic differences in the utilization of neurologic care across a wide range of neurologic conditions in the United States. METHODS: We analyzed nationally representative data from the 2006-2013 Medical Expenditure Panel Survey (MEPS), including information on demographics, patient-reported health conditions, neurology visit rates, and costs. Using diagnostic codes, we identified persons with any self-identified neurologic disorder except back pain, as well as 5 subgroups (Parkinson disease, multiple sclerosis, headache, cerebrovascular disease, and epilepsy)...
May 17, 2017: Neurology
https://www.readbyqxmd.com/read/28514792/autonomic-dysregulation-in-burnout-and-depression-evidence-for-the-central-role-of-exhaustion
#2
Magdalena K Kanthak, Tobias Stalder, LaBarron K Hill, Julian F Thayer, Marlene Penz, Clemens Kirschbaum
Objectives Given the important role of the autonomic nervous system (ANS) in stress regulation, astonishingly little is known about ANS functioning in burnout, a condition arising after prolonged exposure to work-related stress. The current study sought to investigate ANS modulation, as indexed by vagally-mediated heart rate variability (HRV), in relation to burnout symptomatology to (i) distinguish associations between the three dimensions of burnout [emotional exhaustion (EE), cynicism, reduced personal accomplishment] and (ii) investigate overlap in associations with depressive symptomatology...
May 18, 2017: Scandinavian Journal of Work, Environment & Health
https://www.readbyqxmd.com/read/28505261/survival-and-causes-of-death-among-people-with-clinically-diagnosed-synucleinopathies-with-parkinsonism-a-population-based-study
#3
Rodolfo Savica, Brandon R Grossardt, James H Bower, J Eric Ahlskog, Bradley F Boeve, Jonathan Graff-Radford, Walter A Rocca, Michelle M Mielke
Importance: To our knowledge, a comprehensive study of the survival and causes of death of persons with synucleinopathies compared with the general population has not been conducted. Understanding the long-term outcomes of these conditions may inform patients and caregivers of the expected disease duration and may help with care planning. Objective: To compare survival rates and causes of death among patients with incident, clinically diagnosed synucleinopathies and age- and sex-matched referent participants...
May 15, 2017: JAMA Neurology
https://www.readbyqxmd.com/read/28503108/diagnosis-and-treatment-of-cyclothymia-the-primacy-of-temperament
#4
REVIEW
Giulio Perugi, Elie Hantouche, Giulia Vannucchi
BACKGROUND: Contrary to DSM-5 definition based on recurrence of low grade hypomanic and depressive symptoms, cyclothymia is better defined in a neurodevelopmental perspective as an exaggeration of cyclothymic temperament. Emotional dysregulation with extreme mood instability and reactivity is the core features of the complex symptomatology. METHOD: In the present article, we critically reviewed the literature on the diagnosis and treatment of cyclothymia, focusing on the temperamental and neurodevelopmental perspectives...
April 2017: Current Neuropharmacology
https://www.readbyqxmd.com/read/28499112/polygenic-risk-personality-dimensions-and-adolescent-alcohol-use-problems-a-longitudinal-study
#5
James J Li, Jeanne E Savage, Kenneth S Kendler, Matthew Hickman, Liam Mahedy, John Macleod, Jaakko Kaprio, Richard J Rose, Danielle M Dick
OBJECTIVE: Alcohol use problems are common during adolescence and can predict serious negative outcomes in adulthood, including substance dependence and psychopathology. The current study examines the notion that alcohol use problems are driven by polygenic influences and that genetic influences may indirectly affect alcohol use problems through multiple pathways of risk, including variations in personality. METHOD: We used a genome-wide approach to examine associations between genetic risk for alcohol use problems, personality dimensions, and adolescent alcohol use problems in two separate longitudinal population-based samples, the Finnish Twin Cohort (FinnTwin12) and the Avon Longitudinal Study of Parents and Children (ALSPAC)...
May 2017: Journal of Studies on Alcohol and Drugs
https://www.readbyqxmd.com/read/28493652/vitamin-d-deficiency-associated-with-cognitive-functioning-in-psychotic-disorders
#6
Mari Nerhus, Akiah O Berg, Carmen Simonsen, Marit Haram, Beathe Haatveit, Sandra R Dahl, Tiril P Gurholt, Thomas D Bjella, Torill Ueland, Ole A Andreassen, Ingrid Melle
BACKGROUND: Cognitive dysfunctions are core features of psychotic disorders with substantial impact on daily functioning. Vitamin D deficiency has been found to be related to cognitive dysfunctions, but the associations between vitamin D deficiency and cognition in persons with a psychotic disorder are largely unknown. METHODS: This cross-sectional study included 225 patients with a DSM-IV psychotic disorder consecutively recruited from 2003 to 2014 and 159 randomly selected healthy controls, assessed by a cognitive test battery, a clinical protocol (including Structured Clinical Interview for DSM-IV Axis I Disorders and Positive and Negative Syndrome Scale), and a physical examination including vitamin D measurements...
May 9, 2017: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/28490910/optimizing-psychosocial-interventions-in-first-episode-psychosis-current-perspectives-and-future-directions
#7
REVIEW
Nicholas Jk Breitborde, Aubrey M Moe, Arielle Ered, Lauren M Ellman, Emily K Bell
Psychotic-spectrum disorders such as schizophrenia, schizoaffective disorder, and bipolar disorder with psychotic features are devastating illnesses accompanied by high levels of morbidity and mortality. Growing evidence suggests that outcomes for individuals with psychotic-spectrum disorders can be meaningfully improved by increasing the quality of mental health care provided to these individuals and reducing the delay between the first onset of psychotic symptoms and the receipt of adequate psychiatric care...
2017: Psychology Research and Behavior Management
https://www.readbyqxmd.com/read/28488981/a-survey-of-parents-with-children-on-the-autism-spectrum-experience-with-services-and-treatments
#8
Tracy A Becerra, Maria L Massolo, Vincent M Yau, Ashli A Owen-Smith, Frances L Lynch, Phillip M Crawford, Kathryn A Pearson, Magdalena E Pomichowski, Virginia P Quinn, Cathleen K Yoshida, Lisa A Croen
INTRODUCTION: Autism spectrum disorders (ASD) are lifelong neurodevelopmental disorders, and little is known about how parents address the health and psychosocial consequences of ASD. Few studies have examined use of various treatments and services in a large, diverse sample of children with ASD and their families. OBJECTIVE: This paper presents methods to create an autism research resource across multiple large health delivery systems and describes services and treatments used by children with ASD and their families...
2017: Permanente Journal
https://www.readbyqxmd.com/read/28488379/barriers-and-facilitators-to-the-implementation-of-mentalization-based-treatment-mbt-for-borderline-personality-disorder
#9
Dawn L Bales, Roel Verheul, Joost Hutsebaut
There are several evidence-based treatments for borderline personality disorder, but very little is known about the success or failure of implementation in daily practice. This study aims to investigate the success or failure of newly started mentalization-based treatment programs, and to explore the barriers and facilitators. The implementation trajectories of seven different mentalization-based treatment programs in six mental health clinics in the Netherlands were included in a multiple case study combining a qualitative and quantitative design...
May 2017: Personality and Mental Health
https://www.readbyqxmd.com/read/28476484/organization-of-dopamine-and-serotonin-system-anatomical-and-functional-mapping-of-monosynaptic-inputs-using-rabies-virus
#10
REVIEW
Sachie K Ogawa, Mitsuko Watabe-Uchida
Dopamine and serotonin play critical roles in flexible behaviors and are related to various psychiatric and motor disorders. This paper reviews the global organization of dopamine and serotonin systems through recent findings using a modified rabies virus. We first introduce methods for comprehensive mapping of monosynaptic inputs. We then describe quantitative comparisons across the data regarding monosynaptic inputs to dopamine neurons versus serotonin neurons. There is surprising similarity between the input to dopamine neurons in the ventral tegmental area (VTA) and the input to serotonin neurons in the dorsal raphe (DR), suggesting functional interactions between these systems...
May 2, 2017: Pharmacology, Biochemistry, and Behavior
https://www.readbyqxmd.com/read/28476211/-patient-centred-prescription-model-to-improve-adequate-prescription-and-therapeutic-adherence-in-patients-with-multiple-disorders
#11
Joan Espaulella-Panicot, Núria Molist-Brunet, Daniel Sevilla-Sánchez, Javier González-Bueno, Jordi Amblàs-Novellas, Núria Solà-Bonada, Carles Codina-Jané
Patients with multiple disorders and on multiple medication are often associated with clinical complexity, defined as a situation of uncertainty conditioned by difficulties in establishing a situational diagnosis and decision-making. The patient-centred care approach in this population group seems to be one of the best therapeutic options. In this context, the preparation of an individualised therapeutic plan is the most relevant practical element, where the pharmacological plan maintains an important role...
May 2, 2017: Revista Española de Geriatría y Gerontología
https://www.readbyqxmd.com/read/28475593/association-between-social-support-and-post-traumatic-stress-disorder-symptoms-among-chinese-patients-with-ovarian-cancer-a-multiple-mediation-model
#12
Chunli Liu, Yi Zhang, Hong Jiang, Hui Wu
Post-traumatic stress disorder (PTSD) symptoms can develop after person experiences one or more traumatic events. Little research, however, has been done on PTSD symptoms of patients with ovarian cancer. The present study aimed to estimate the prevalence of PTSD symptoms in patients with ovarian cancer in China; the effects of demographic and clinical variables on PTSD symptoms; multiple mediation roles in the association between social support and PTSD symptoms in patients with ovarian cancer in China. We collected demographic and clinical information of patients with ovarian cancer in the first and second hospitals of China Medical University between January 1, 2014 and December 31, 2015...
2017: PloS One
https://www.readbyqxmd.com/read/28474374/mobile-phone-messaging-for-illicit-drug-and-alcohol-dependence-a-systematic-review-of-the-literature
#13
Babak Tofighi, Joseph M Nicholson, Jennifer McNeely, Frederick Muench, Joshua D Lee
ISSUES: Mobile phone use has increased dramatically and concurrent with rapid developments in mobile phone-based health interventions. The integration of text messaging interventions promises to optimise the delivery of care for persons with substance dependence with minimal disruption to clinical workflows. We conducted a systematic review to assess the acceptability, feasibility and clinical impact of text messaging interventions for persons with illicit drug and alcohol dependence...
May 5, 2017: Drug and Alcohol Review
https://www.readbyqxmd.com/read/28474253/prevalence-and-burden-of-headache-disorders-in-lithuania-and-their-public-health-and-policy-implications-a-population-based-study-within-the-eurolight-project
#14
Daiva Rastenytė, Dalia Mickevičienė, Lars Jacob Stovner, Hallie Thomas, Colette Andrée, Timothy J Steiner
BACKGROUND: The Eurolight project assessed the impact of headache disorders in ten EU countries, using the same structured questionnaire but varying sampling methods. In Lithuania, sample selection employed methods in line with consensus recommendations for population-based burden-of-headache studies. METHODS: The survey was cross-sectional. We identified, from the Residents' Register Service, a sample of inhabitants of Kaunas city and surrounding Kaunas region reflecting age (in the range 18-65 years), gender and rural/urban distributions of Lithuania...
December 2017: Journal of Headache and Pain
https://www.readbyqxmd.com/read/28472591/association-between-personality-traits-and-escitalopram-treatment-efficacy-in-panic-disorder
#15
Ülle Võhma, Mait Raag, Innar Tõru, Anu Aluoja, Eduard Maron
BACKGROUND: There is strong evidence to suggest that personality factors may interact with the development and clinical expression of panic disorder (PD). A greater understanding of these relationships may have important implications for clinical practice and implications for searching reliable predictors of treatment outcome. AIMS: The study aimed to examine the effect of escitalopram treatment on personality traits in PD patients, and to identify whether the treatment outcome could be predicted by any personality trait...
May 4, 2017: Nordic Journal of Psychiatry
https://www.readbyqxmd.com/read/28469582/exploring-the-intersections-of-trauma-structural-adversity-and-psychosis-among-a-primarily-african-american-sample-a-mixed-methods-analysis
#16
Cherise Rosen, Nev Jones, Eleanor Longden, Kayla A Chase, Mona Shattell, Jennifer K Melbourne, Sarah K Keedy, Rajiv P Sharma
Traumatic life events (TLEs) have been associated with multiple psychiatric diagnoses, including anxiety disorders, major depression, PTSD, and psychosis. To advance our understanding of the complex interactions between forms of adversity as they manifest across the lifespan, psychosis, and symptom content, we undertook a mixed-methods investigation of TLEs and psychosis. Our research explored the association between cumulative exposures, type of TLE, and proximity to the traumatic event and psychosis; the association between TLEs and clinical symptomology including specific types of delusions and/or hallucinations; and how qualitative data further inform understanding of complex relationships and patterns of past trauma and symptoms as they unfold over time...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/28468012/genetic-discoveries-highlight-environmental-factors-as-key-drivers-of-liver-disease
#17
Brian K Chung, Tom H Karlsen
BACKGROUND: Over the last 50 years, genetic studies have uncovered a spectrum of rare and common alleles that confer susceptibility to both Mendelian and complex forms of liver disease. For disorders of Mendelian inheritance, identification of the causal variants has demonstrated that common environmental exposures can elicit severe liver pathogenesis in predisposed individuals. Specific environmental triggers for complex liver disorders are largely unknown; however, large-scale association studies indicate that environmental triggers are the predominant factors in driving liver pathophysiology...
2017: Digestive Diseases
https://www.readbyqxmd.com/read/28454922/paliperidone-palmitate-once-monthly-maintains-improvement-in-functioning-domains-of-the-personal-and-social-performance-scale-compared-with-placebo-in-subjects-with-schizoaffective-disorder
#18
Dong-Jing Fu, Ibrahim Turkoz, David Walling, Jean-Pierre Lindenmayer, Nina R Schooler, Larry Alphs
OBJECTIVE: Evaluate the effect of paliperidone palmitate once-monthly (PP1M) injectable on the specific functioning domains of the Personal and Social Performance (PSP) scale in patients with schizoaffective disorder (SCA) participating in a long-term study. METHODS: This study (NCT01193153) included both in- and outpatient subjects with SCA experiencing an acute exacerbation of psychotic and mood symptoms. Subjects were treated with PP1M either as monotherapy or in combination with antidepressants or mood stabilizers during a 25-week open-label (OL) phase...
April 25, 2017: Schizophrenia Research
https://www.readbyqxmd.com/read/28453592/-cutaneous-myiasis-due-to-cochliomyia-hominivorax-associated-with-seborrheic-dermatitis
#19
Perla Calderón H, Camilo Rojas E, Werner Apt B, Douglas Castillo O
Myiasis is an infestation of tissues and organs of humans and animals by Diptera larvae (flies, horseflies, mosquitoes). They are located at different body sites, and classified clinically as cutaneous, visceral and cavitary. We report a 26-year-old woman with a history of seborrheic dermatitis and recent trip to Brazil. She presented with a seven days history of suppurating wounds in the parieto-occipital area of the scalp. At physical examination we found three ulcers of approximately 1.5 cm each, with multiple mobile larvae inside...
February 2017: Revista Médica de Chile
https://www.readbyqxmd.com/read/28438236/personal-and-macro-systemic-factors-as-predictors-of-quality-of-life-in-chronic-schizophrenia
#20
Yolanda Fontanil-Gómez, María A Alcedo Rodríguez, María I Gutiérrez López
BACKGROUND: The goal of this research was to establish possible predictive factors for both subjective and externally assessed quality of life in people with chronic schizophrenia. METHODS: Sixty-eight people with schizophrenia took part in the study and were assessed using the World Health Organisation Quality of Life Assessment - Brief Version (WHOQOL-BREF), the Quality of Life Scale (QLS), the Positive and Negative Syndrome Scale for Schizophrenia (PANSS), the Global Assessment of Functioning (GAF), the Social Functioning Scale (SFS) tests...
May 2017: Psicothema
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