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european journal of vascular medicine

Biswanath Dinda, Anthony M Kyriakopoulos, Subhajit Dinda, Vassilis Zoumpourlis, Nikolaos S Thomaidis, Aristea Velegraki, Charlambos Markopoulos, Manikarna Dinda
ETHNOPHARMACOLOGICAL RELEVANCE: Cornus mas L. (cornelian cherry) fruits have been used for centuries as traditional cuisine and folk medicine in various countries of Europe and Asia. In folk medicines, the fruits and other parts of the plant have been used for prevention and treatment of a wide range of diseases such as diabetes, diarrhea, gastrointestinal disorders, fevers, rheumatic pain, skin and urinary tract infections, kidney and liver diseases, sunstroke, among others. This review provides a systematic and constructive overview of ethnomedicinal uses, chemical constituents and pharmacological activities of this plant as well as future research need for its commercial utilization as nutraceutical food supplement and medicine...
October 2, 2016: Journal of Ethnopharmacology
Thomas M MacDonald, Ian Ford, George Nuki, Isla S Mackenzie, Raffaele De Caterina, Evelyn Findlay, Jesper Hallas, Christopher J Hawkey, Stuart Ralston, Matthew Walters, John Webster, John McMurray, Fernando Perez Ruiz, Claudine G Jennings
INTRODUCTION: Gout affects 2.5% of the UK's adult population and is now the most common type of inflammatory arthritis. The long-term management of gout requires reduction of serum urate levels and this is most often achieved with use of xanthine oxidase inhibitors, such as allopurinol. Febuxostat is the first new xanthine oxidase inhibitor since allopurinol and was licensed for use in 2008. The European Medicines Agency requested a postlicensing cardiovascular safety study of febuxostat versus allopurinol, which has been named the Febuxostat versus Allopurinol Streamlined trial (FAST)...
2014: BMJ Open
Anders Berg Jørgensen, Ruth Frikke-Schmidt, Børge G Nordestgaard, Anne Tybjærg-Hansen
BACKGROUND: High plasma levels of nonfasting triglycerides are associated with an increased risk of ischemic cardiovascular disease. Whether lifelong low levels of nonfasting triglycerides owing to mutations in the gene encoding apolipoprotein C3 (APOC3) are associated with a reduced risk of ischemic cardiovascular disease in the general population is unknown. METHODS: Using data from 75,725 participants in two general-population studies, we first tested whether low levels of nonfasting triglycerides were associated with reduced risks of ischemic vascular disease and ischemic heart disease...
July 3, 2014: New England Journal of Medicine
Matthew Pagni, Nickalus R Khan, Harris L Cohen, Asim F Choudhri
RATIONALE AND OBJECTIVES: The number of citations a publication receives can be used to show its impact on a field of study. It may indicate the educational interest in a given population or underline a perceived or real educational gap. This article identifies and characterizes the 100 top cited publications in radiologic journals as of May 2013. MATERIALS AND METHODS: All clinical radiologic journals listed by Thomson Reuters Journal Citation Reports in 2011 were identified...
August 2014: Academic Radiology
Kusum Mathews, Mario Katigbak, Aydin Uzunpinar
SESSION TYPE: Miscellaneous Case Report Posters IPRESENTED ON: Tuesday, October 23, 2012 at 01:30 PM - 02:30 PMINTRODUCTION: Amyloidosis can involve lung parenchyma in a diffuse, tracheobronchial, or parenchymal pattern and can be associated with pulmonary hemorrhage. We present a case of nodular parenchymal amyloidosis presenting with both hemoptysis and spontaneous hemothorax.CASE PRESENTATION: A 78 year-old woman with breast and renal amyloidosis, presented with acute abdominal pain. She developed acute hematemesis, requiring intubation for hypoxemic respiratory failure...
October 1, 2012: Chest
L Buratti
INTRODUCTION: With the continuing worldwide shortage of anesthesiologists, the demands of clinical duties allow very little time for research activities. Every dedicated biomedical center should provide doctors and scientists with the proper environment to facilitate education, clinical practice and research activities and promote publication in international peer-review journals. METHODS: In this observational study, the Scopus database was searched for publications ( 2004-2009 ) to identify the most prolific authors among Italian anesthesiologists and intensive care specialists working in Italy...
2009: HSR Proceedings in Intensive Care & Cardiovascular Anesthesia
Tine L M de Backer, Robert Vander Stichele, Philippe Lehert, Luc Van Bortel
BACKGROUND: Lifestyle changes and cardiovascular prevention measures are a primary treatment for intermittent claudication (IC). Symptomatic treatment with vasoactive agents (Anatomic Therapeutic Chemical Classification (ATC) for medicines from the World Health Organisation class CO4A) is controversial. OBJECTIVES: To evaluate evidence on the efficacy and safety of oral naftidrofuryl (ATC CO4 21) versus placebo on the pain-free walking distance (PFWD) of people with IC by using a meta-analysis based on individual patient data (IPD)...
2012: Cochrane Database of Systematic Reviews
Peter A Schneider, A Ross Naylor
Vascular surgery has matured to the point that there exists robust bodies of literature exploring many of our therapies. However, this evidence is but one of the factors that dictate medical practice. Others include local patient demographics, the practical implications of healthcare delivery, and an individual surgeon's interpretation of this evidence, which can be somewhat subjective. As a result, there are numerous examples of vascular specialists' practice patterns differing depending on their geographic location...
August 2010: Journal of Vascular Surgery
V Mallika, Binita Goswami, Medha Rajappa
Atherosclerosis is the root cause of the biggest killer of the 21st century. Mechanisms contributing to atherogenesis are multiple and complex. A number of theories-including the role of dyslipidemia, hypercoagulability, oxidative stress, endothelial dysfunction, and inflammation and infection by certain pathogens-have been propounded from time to time explain this complex phenomenon. Recently it has been suggested that atherosclerosis is a multifactorial, multistep disease that involves chronic inflammation at every step, from initiation to progression, and that all the risk factors contribute to pathogenesis by aggravating the underlying inflammatory process...
October 2007: Angiology
Francesco Montorsi, Alberto Briganti, Andrea Salonia, Patrizio Rigatti, Arthur L Burnett
INTRODUCTION AND OBJECTIVES: To systematically analyze and review the available evidence about the potential role of chronic administration of phosphodiesterase type 5 (PDE-5) inhibitors for the cure of erectile dysfunction (ED) based on clinical and basic science data. METHODS: Analysis of published full-length papers that were identified with Medline and Cancerlit from January 1993 to September 2005. Abstracts published in the journals European Urology, the Journal of Urology, the International Journal of Impotence Research, and the Journal of Sexual Medicine as official proceedings of internationally known scientific societies held in the same time period were also assessed...
June 2006: European Urology
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