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Artificial heart

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https://www.readbyqxmd.com/read/29461965/post-ventricular-premature-contraction-phase-correction-improves-the-predictive-value-of-average-t-wave-alternans-in-ambulatory-ecg-recordings
#1
Alba Martin-Yebra, Violeta Monasterio, Iwona Cygankiewicz, Antoni Bayes-de-Luna, Enrico G Caiani, Pablo Laguna, Juan Pablo Martinez
OBJECTIVE: We proposed and evaluated a method for correcting possible phase shifts provoked by the presence of ventricular premature contractions (VPCs) for a better assessment of T-wave alternans (TWA). Methods: First, we synthesized ECG signals with artificial TWA in the presence of different noise sources. Then, we assessed the prognostic value for sudden cardiac death (SCD) of the long-term average of TWA amplitude (the index of average alternans, ) in ambulatory ECG signals from congestive heart failure (CHF) and evaluated whether it is sensitive to the presence of VPCs...
March 2018: IEEE Transactions on Bio-medical Engineering
https://www.readbyqxmd.com/read/29448930/a-prediction-study-of-warfarin-individual-stable-dose-after-mechanical-heart-valve-replacement-adaptive-neural-fuzzy-inference-system-prediction
#2
Huan Tao, Qian Li, Qin Zhou, Jie Chen, Bo Fu, Jing Wang, Wenzhe Qin, Jianglong Hou, Jin Chen, Li Dong
BACKGROUND: It's difficult but urgent to achieve the individualized rational medication of the warfarin, we aim to predict the individualized warfarin stable dose though the artificial intelligent Adaptive neural-fuzzy inference system (ANFIS). METHODS: Our retrospective analysis based on a clinical database, involving 21,863 patients from 15 Chinese provinces who receive oral warfarin after the heart valve replacement. They were allocated into four groups: the external validation group (A group), the internal validation group (B group), training group (C group) and stratified training group (D group)...
February 15, 2018: BMC Surgery
https://www.readbyqxmd.com/read/29444322/physiological-reactions-to-long-term-fishing-in-the-barents-sea
#3
B Netterstrøm, Å M Hansen, D Isaacson, A M Simonsen, P Weihe
Background: Fishing in distant waters for months may induce physiological stress. Aims: To assess the physiological stress reactions in fishermen working for 2-3 months continuously in 6-h shifts on trawlers in the Barents Sea. Methods: The crew of five trawlers fishing in the Barents Sea from January to April 2004 were invited to participate. In the week before and 5-7 days after the trip, the following measures were collected: salivary cortisol four times a day, 24-h urinary cortisol, blood pressure, heart rate, serum cholesterol, serum high-density lipoprotein (HDL-cholesterol), HbA1c (glycosylated haemoglobin) and weight...
February 10, 2018: Occupational Medicine
https://www.readbyqxmd.com/read/29436002/peripheral-artery-disease-and-continuous-flow-left-ventricle-assist-device-an-engaging-complement-analysis-may-help-to-guide-treatment
#4
Calogero Falletta, Salvatore Pasta, Giuseppe Maria Raffa, Francesca Crinò, Sergio Sciacca, Francesco Clemenza
Use of continuous flow left ventricle assist device (CF-LVAD) in advanced heart failure (HF) patients results in clinically relevant improvements in survival, functional capacity, and quality of life. Peripheral artery disease (PAD) can occur in patients with CF-LVAD due to the high rate of concomitance between risk factors for atherosclerosis and HF. Diagnosis of PAD can be difficult in the specific setting of a patient supported by this kind of device because of the marked alteration in waveform morphology and velocity created by the artificial physiology of an LVAD...
February 13, 2018: Artificial Organs
https://www.readbyqxmd.com/read/29426997/transcatheter-heart-valve-for-aortic-valve-implantation-republication-of-the-article-published-in-the-japanese-journal-of-artificial-organs
#5
REVIEW
Hideki Oshima
This review was created based on a translation of the Japanese review first reported in the Japanese Journal of Artificial Organs in 2015 (vol. 44, no. 3, pp. 136-140), with some modifications.
February 9, 2018: Journal of Artificial Organs: the Official Journal of the Japanese Society for Artificial Organs
https://www.readbyqxmd.com/read/29424032/a-self-powered-sensor-mimicking-slow-and-fast-adapting-cutaneous-mechanoreceptors
#6
Kyoung-Yong Chun, Young Jun Son, Eun-Seok Jeon, Sehan Lee, Chang-Soo Han
Highly efficient human skin systems transmit fast adaptive (FA) and slow adaptive (SA) pulses selectively or consolidatively to the brain for a variety of external stimuli. The integrated analysis of these signals determines how humans perceive external physical stimuli. Here, a self-powered mechanoreceptor sensor based on an artificial ion-channel system combined with a piezoelectric film is presented, which can simultaneously implement FA and SA pulses like human skin. This device detects stimuli with high sensitivity and broad frequency band without external power...
February 9, 2018: Advanced Materials
https://www.readbyqxmd.com/read/29384497/an-improved-optimization-algorithm-of-3-compartmental-model-with-spill-over-and-partial-volume-corrections-for-dynamic-fdg-pet-images-of-small-animal-heart-in-vivo
#7
Yinlin Li, Bijoy K Kundu
The 3- Compartment model with spill-over (SP) and partial volume corrections (PV) has been widely used for noninvasive kinetic parameters study for dynamic FDG PET images of small animal heart in vivo. However, the approach still suffers from the estimation uncertainty or slow convergence caused by the commonly used optimization algorithms. The aim of the study was to develop an improved optimization algorithm with better estimation performance. Femoral artery blood samples, image derived input functions (IDIFs) from heart ventricles and myocardial time-activity curves (TACs) were derived from sixteen C57BL/6 mice data obtained from the UCLA Mouse Quantitation Program...
January 31, 2018: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/29378052/soda-intake-is-directly-associated-with-serum-c-reactive-protein-concentration-in-mexican-women
#8
Martha Tamez, Adriana Monge, Ruy López-Ridaura, Guy Fagherazzi, Sabina Rinaldi, Eduardo Ortiz-Panozo, Elsa Yunes, Isabelle Romieu, Martin Lajous
Background: Soda intake is associated with an increased risk of cardiovascular disease. Consumption of diet sodas, often considered healthy alternatives to sodas, could also increase the likelihood of cardiovascular outcomes. Objective: This study aims to evaluate the relation between soda and diet soda and biomarkers of cardiovascular risk. Methods: We conducted a cross-sectional analysis among 825 Mexican women free of diabetes, cardiovascular disease, and cancer, and for whom serum concentrations of C-reactive protein (CRP), C-peptide, adiponectin, and leptin were available...
January 1, 2018: Journal of Nutrition
https://www.readbyqxmd.com/read/29374348/driver-electronics-design-and-control-for-a-total-artificial-heart-linear-motor
#9
Kristin Unthan, Elena Cuenca-Navalon, Benedikt Pelletier, Thomas Finocchiaro, Ulrich Steinseifer
For any implantable device size and efficiency are critical properties. Thus, a linear motor for a Total Artificial Heart was optimized with focus on driver electronics and control strategies. Hardware requirements were defined from power supply and motor setup. Four full bridges were chosen for the power electronics. Shunt resistors were set up for current measurement. Unipolar and bipolar switching for power electronics control were compared regarding current ripple and power losses. Here, unipolar switching showed smaller current ripple and required less power to create the necessary motor forces...
January 27, 2018: Medical & Biological Engineering & Computing
https://www.readbyqxmd.com/read/29374196/predicting-non-melanoma-skin-cancer-via-a-multi-parameterized-artificial-neural-network
#10
David Roffman, Gregory Hart, Michael Girardi, Christine J Ko, Jun Deng
Ultraviolet radiation (UVR) exposure and family history are major associated risk factors for the development of non-melanoma skin cancer (NMSC). The objective of this study was to develop and validate a multi-parameterized artificial neural network based on available personal health information for early detection of NMSC with high sensitivity and specificity, even in the absence of known UVR exposure and family history. The 1997-2015 NHIS adult survey data used to train and validate our neural network (NN) comprised of 2,056 NMSC and 460,574 non-cancer cases...
January 26, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29371040/total-artificial-heart-using-bilateral-paracorporeal-pulsatile-vads-in-an-8-2kg-child
#11
Ronald K Woods, Steve Kindel, Michael E Mitchell, Viktor Hraska, Robert A Niebler
We present a case report illustrating a novel method of placing a total artificial heart (TAH) in a small child.
January 22, 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29365118/initial-in-vitro-testing-of-a-paediatric-continuous-flow-total-artificial-heart
#12
Kiyotaka Fukamachi, Jamshid H Karimov, David J Horvath, Gengo Sunagawa, Nicole A Byram, Barry D Kuban, Nader Moazami
OBJECTIVES: Mechanical circulatory support has become standard therapy for adult patients with end-stage heart failure; however, in paediatric patients with congenital heart disease, the options for chronic mechanical circulatory support are limited to paracorporeal devices or off-label use of devices intended for implantation in adults. Congenital heart disease and cardiomyopathy often involve both the left and right ventricles; in such cases, heart transplantation, a biventricular assist device or a total artificial heart is needed to adequately sustain both pulmonary and systemic circulations...
January 19, 2018: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/29363348/reliability-of-internal-and-external-load-parameters-in-recreational-football-soccer-for-health
#13
Marco Beato, Mikael Jamil, Gavin Devereux
There is limited research focussed around the analysis of internal and external load parameters during football health programmes. The aim of this study was to assess the reliability of internal and external load parameters in this activity. Thrity subjects were enrolled (mean ± SDs; age = 43 ± 3 years, weight = 84 ± 14 kg, height = 176 ± 7 cm, BMI = 27.1 ± 3, VO2max = 40.7 ± 3.4 ml.kg.min-1). The football matches (five a-side) took place on an artificial grass outdoor field (pitch size of 36 × 18...
January 24, 2018: Research in Sports Medicine
https://www.readbyqxmd.com/read/29360282/left-ventricular-assist-device-patient-maintained-on-home-hemodialysis-a-novel-class-of-patients-to-the-home-dialysis-population
#14
Ramy M Hanna, Daniel Cruz, Umut Selamet, Huma Hasnain, Murray Kwon, Arnold Baas, James Wilson
Severe heart failure is increasingly being managed by cardiac transplantation, and in some cases mechanical support devices serve as destination therapies. Left ventricular assist devices (LVADs) were approved for destination therapy for end stage heart failure patients before the more advanced total artificial heart modality became available. One common complication of mechanical assist device placement is acute kidney injury. Historically, patients with mechanical support devices have had to have inpatient hemodialysis until combined heart kidney transplant...
January 23, 2018: Hemodialysis International
https://www.readbyqxmd.com/read/29356445/chronic-repeated-exposure-to-weather-related-stimuli-elicits-few-symptoms-of-chronic-stress-in-captive-molting-and-non-molting-european-starlings-sturnus-vulgaris
#15
Robert de Bruijn, J Michael Reed, L Michael Romero
Repeated exposure to acute stressors causes dramatic changes in an animal's stress physiology and the cumulative effects are often called chronic stress. Recently we showed that short-term exposure to weather-related stimuli, such as temperature change, artificial precipitation, and food restriction, cause acute responses in captive European starlings (Sturnus vulgaris). Here, we examined the effect of repeated exposure to weather-related stressors on heart rate and corticosterone (CORT) of captive non-molting and molting European starlings...
October 2017: Journal of Experimental Zoology. Part A, Ecological and Integrative Physiology
https://www.readbyqxmd.com/read/29350622/beyond-hrv-attractor-reconstruction-using-the-entire-cardiovascular-waveform-data-for-novel-feature-extraction
#16
Philip J Aston, Mark I Christie, Ying H Huang, Manasi Nandi
Advances in monitoring technology allow blood pressure waveforms to be collected at sampling frequencies of 250-1000Hz for long time periods. However, much of the raw data are under analysed. Heart rate variability (HRV) methods, in which beat-to-beat interval lengths are extracted and analysed, have been extensively studied, However, this approach discards the majority of the raw data. OBJECTIVE: Our aim is to detect changes in the shape of the waveform in long streams of blood pressure data...
January 19, 2018: Physiological Measurement
https://www.readbyqxmd.com/read/29349805/hybrid-continuous-flow-total-artificial-heart
#17
Carson Fox, Steven Chopski, Nohra Murad, Paul Allaire, Robert Mentzer, Joseph Rossano, Francisco Arabia, Amy Throckmorton
Clinical studies using total artificial hearts (TAHs) have demonstrated that pediatric and adult patients derive quality-of-life benefits from this form of therapy. Two clinically-approved TAHs and other pumps under development, however, have design challenges and limitations, including thromboembolic events, neurologic impairment, infection risk due to large size and percutaneous drivelines, and lack of ambulation, to name a few. To address these limitations, we are developing a hybrid-design, continuous-flow, implantable or extracorporeal, magnetically-levitated TAH for pediatric and adult patients with heart failure...
January 18, 2018: Artificial Organs
https://www.readbyqxmd.com/read/29347013/correlations-in-magnitude-series-to-assess-nonlinearities-application-to-multifractal-models-and-heartbeat-fluctuations
#18
Pedro A Bernaola-Galván, Manuel Gómez-Extremera, A Ramón Romance, Pedro Carpena
The correlation properties of the magnitude of a time series are associated with nonlinear and multifractal properties and have been applied in a great variety of fields. Here we have obtained the analytical expression of the autocorrelation of the magnitude series (C_{|x|}) of a linear Gaussian noise as a function of its autocorrelation (C_{x}). For both, models and natural signals, the deviation of C_{|x|} from its expectation in linear Gaussian noises can be used as an index of nonlinearity that can be applied to relatively short records and does not require the presence of scaling in the time series under study...
September 2017: Physical Review. E
https://www.readbyqxmd.com/read/29324512/exercise-capacity-in-patients-with-the-total-artificial-heart
#19
Justin M Canada, Ronald K Evans, Antonio Abbate, Ross Arena, Daniel G Tang, Vigneshwar Kasirajan, Keyur B Shah
There is a dearth of information regarding the functional abilities of patients with the total artificial heart (TAH). Increased utilization of the TAH and patient discharge to home with the portable unit necessitates a shift in focus to quality of life, which includes quantifying and ultimately optimizing functional capacity. To date, only single-patient case studies have described the exercise response of the TAH patient. Fourteen patients with the TAH underwent cardiopulmonary exercise testing with concurrent analysis of TAH device function...
January 10, 2018: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://www.readbyqxmd.com/read/29320885/a-pilot-study-validating-select-research-grade-and-consumer-based-wearables-throughout-a-range-of-dynamic-exercise-intensities-in-persons-with-and-without-type-1-diabetes-a-novel-approach
#20
Loren Yavelberg, Dessi Zaharieva, Ali Cinar, Michael C Riddell, Veronica Jamnik
BACKGROUND: The increasing popularity of wearable technology necessitates the evaluation of their accuracy to differentiate physical activity (PA) intensities. These devices may play an integral role in customizing PA interventions for primary prevention and secondary management of chronic diseases. For example, in persons with type 1 diabetes (T1D), PA greatly affects glucose concentrations depending on the intensity, mode (ie, aerobic, anaerobic, mixed), and duration. This variability in glucose responses underscores the importance of implementing dependable wearable technology in emerging avenues such as artificial pancreas systems...
January 1, 2018: Journal of Diabetes Science and Technology
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