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https://www.readbyqxmd.com/read/28107271/perioperative-care-of-the-patient-with-the-total-artificial-heart
#1
Jill Yaung, Francisco A Arabia, Michael Nurok
Advanced heart failure continues to be a leading cause of morbidity and mortality despite improvements in pharmacologic therapy. High demand for cardiac transplantation and shortage of donor organs have led to an increase in the utilization of mechanical circulatory support devices. The total artificial heart is an effective biventricular assist device that may be used as a bridge to transplant and that is being studied for destination therapy. This review discusses the history, indications, and perioperative management of the total artificial heart with emphasis on the postoperative concerns...
January 19, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28105119/clinical-observation-on-the-treatment-of-acute-liver-failure-by-combined-non-biological-artificial-liver
#2
Maoqin Li, Jingxi Sun, Jiaqiong Li, Zaixiang Shi, Jiyuan Xu, Bo Lu, Shuli Cheng, Yanjun Xu, Xiaomeng Wang, Xianjiang Zhang
The clinical efficacy and safety of different combinations of non-bio artificial liver in the treatment of acute liver failure was examined. A total of 61 cases were selected under blood purification treatment from the patients with severe acute liver failure admitted to the severe disease department of the hospital from December, 2010 to December, 2015. Three types of artificial liver combinations were observed, i.e., plasma exchange plus hemoperfusion plus continuous venovenous hemodiafiltration (PE+HP+CVVHDF), PE+CVVHDF and HP+CVVHDF...
December 2016: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28104190/in%C3%A2-vitro-coronary-flow-after-transcatheter-aortic-valve-in-valve-implantation-a-comparison-of-2-valves
#3
Sina Stock, Michael Scharfschwerdt, Roza Meyer-Saraei, Doreen Richardt, Efstratios I Charitos, Hans-Hinrich Sievers, Thorsten Hanke
BACKGROUND: Transcatheter aortic valve-in-valve implantation (TAVI-ViV) is an evolving treatment strategy for degenerated surgical aortic valve bioprostheses (SAVBs). However, there is some concern regarding coronary obstruction, especially after TAVI-ViV in calcified SAVBs with externally mounted leaflets. We investigated in vitro coronary flow and hydrodynamics after TAVI-ViV using 2 modern SAVBs with externally and internally mounted leaflets. METHODS: Aortic root models including known risk factors for coronary obstruction served for the implantation of SAVBs with either externally mounted leaflets (St Jude Trifecta, size 25) or internally mounted leaflets (Edwards Perimount Magna Ease, size 25)...
February 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28103597/psychophysiological-effects-of-a-single-short-and-moderately-bright-room-light-exposure-on-mildly-depressed-geriatric-inpatients-a-pilot-study
#4
Markus Canazei, Wilfried Pohl, Kathrin Bauernhofer, Ilona Papousek, Helmut K Lackner, Harald R Bliem, Josef Marksteiner, Elisabeth M Weiss
BACKGROUND: Light interventions typically exert their mood-related effects during morning bright light exposures over several weeks. Evidence about immediate ambient room light effects on depressed individuals is still sparse. OBJECTIVE: The present study aimed at examining the acute effects of a single moderately bright room light exposure on mood, and behavioural and cardiac stress reactions of mildly depressed geriatric inpatients during a short cognitive stimulation and while resting...
January 20, 2017: Gerontology
https://www.readbyqxmd.com/read/28095077/running-performance-with-nutritive-and-non-nutritive-sweetened-mouth-rinses
#5
Keely H Hawkins, Sridevi Krishnan, Lara Ringos, Vanessa Garcia, Jamie A Cooper
: Mouth rinsing (MR) with carbohydrate during exercise has been shown to act as an ergogenic aid. PURPOSE: To investigate if nutritive or nonnutritive sweetened MR affect exercise performance, and to assess the influence of sweetness intensity on endurance performance during a time-trial (TT). METHODS: This randomized, single blinded study had 4 treatment conditions. 16 subjects (9 men, 7 women) completed a 12.8km TT four different times. During each TT, subjects MR and expectorated a different solution at time 0 and every 12...
January 17, 2017: International Journal of Sports Physiology and Performance
https://www.readbyqxmd.com/read/28079567/cardiac-calcium-release-channel-ryanodine-receptor-2-regulation-by-halogenated-anesthetics
#6
Derek R Laver, John Attia, Christopher Oldmeadow, Anthony W Quail
BACKGROUND: Halogenated anesthetics activate cardiac ryanodine receptor 2-mediated sarcoplasmic reticulum Ca release, leading to sarcoplasmic reticulum Ca depletion, reduced cardiac function, and providing cell protection against ischemia-reperfusion injury. Anesthetic activation of ryanodine receptor 2 is poorly defined, leaving aspects of the protective mechanism uncertain. METHODS: Ryanodine receptor 2 from the sheep heart was incorporated into artificial lipid bilayers, and their gating properties were measured in response to five halogenated anesthetics...
January 12, 2017: Anesthesiology
https://www.readbyqxmd.com/read/28075489/cough-augmentation-techniques-for-extubation-or-weaning-critically-ill-patients-from-mechanical-ventilation
#7
REVIEW
Louise Rose, Neill Kj Adhikari, David Leasa, Dean A Fergusson, Douglas McKim
BACKGROUND: There are various reasons why weaning and extubation failure occur, but ineffective cough and secretion retention can play a significant role. Cough augmentation techniques, such as lung volume recruitment or manually- and mechanically-assisted cough, are used to prevent and manage respiratory complications associated with chronic conditions, particularly neuromuscular disease, and may improve short- and long-term outcomes for people with acute respiratory failure. However, the role of cough augmentation to facilitate extubation and prevent post-extubation respiratory failure is unclear...
January 11, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28062539/tissue-expander-as-a-routine-component-of-50cc-total-artificial-heart-implantation-for-bridge-to-transplant
#8
Ryan Avery, Samata R Paidy, Roy Keller, Scott Lick, Richard G Smith, Zain Khalpey
No abstract text is available yet for this article.
January 2017: Circulation. Heart Failure
https://www.readbyqxmd.com/read/28048860/su-f-p-54-guidelines-to-check-image-registration-qa-of-a-clinical-deformation-registration-software-a-single-institution-preliminary-study
#9
G Gill, S Souri, A Rea, Y Chen, J Antone, X Qian, A Riegel, P Taylor, M Marrero, F Diaz, Y Cao, A Jamshidi, S Barley, V Sorell, G Karangelis, T Button, E Klein
PURPOSE: The objective of this study is to verify and analyze the accuracy of a clinical deformable image registration (DIR) software. METHODS: To test clinical DIR software qualitatively and quantitatively, we focused on lung radiotherapy and analyzed a single (Lung) patient CT scan. Artificial anatomical changes were applied to account for daily variations during the course of treatment including the planning target volume (PTV) and organs at risk (OAR). The primary CT (pCT) and the structure set (pST) was deformed with commercial tool (ImSimQA-Oncology Systems Limited) and after artificial deformation (dCT and dST) sent to another commercial tool (VelocityAI-Varian Medical Systems)...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28009714/worldwide-experience-with-the-syncardia-total-artificial-heart-in-the-pediatric-population
#10
David L S Morales, Angela Lorts, Raheel Rizwan, Farhan Zafar, Francisco A Arabia, Chet R Villa
No abstract text is available yet for this article.
December 20, 2016: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://www.readbyqxmd.com/read/28007267/off-pump-neochord-mitral-valve-repair-to-simultaneously-treat-posterior-leaflet-prolapse-and-systolic-anterior-motion
#11
Stefano Salizzoni, Matteo Marro, Chiara Rovera, Giovanni Speziali, Mauro Rinaldi
This case represents the first report of complete elimination of systolic anterior motion by beating-heart implantation of artificial chordae tendineae on a prolapsing and redundant posterior leaflet.
January 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28007060/mechanical-circulatory-support-of-the-fontan-patient
#12
REVIEW
Ronald K Woods, Nancy S Ghanayem, Michael E Mitchell, Steven Kindel, Robert A Niebler
Because of the inadequacies inherent to a circulation supported by a single ventricle, many Fontan patients will experience failure of their circulation. To date, there is no medical regimen that reliably and consistently restores circulatory function in these patients. Because of the shortage of donor organs and the fact that many of these patients present with features that either preclude or render heart transplantation a high risk, there is an intense need to better understand how mechanical circulatory support (MCS) may benefit these patients...
January 2017: Seminars in Thoracic and Cardiovascular Surgery. Pediatric Cardiac Surgery Annual
https://www.readbyqxmd.com/read/28007058/the-50-50-cc-total-artificial-heart-trial-extending-the-benefits-of-the-total-artificial-heart-to-underserved-populations
#13
REVIEW
Dennis Wells, Chet R Villa, David Luís Simón Morales
While use of the total artificial heart (TAH) is growing, the use of the device is not uniform across the gender and age spectrum because the vast majority of implants are in adult males. SynCardia has recently developed a smaller 50 cc TAH that was designed to accommodate patients with a body surface area as low as 1.2 m(2) (potentially even lower using virtual implantation). Herein, we describe the early use of the 50 cc TAH (10 implants in the US and 18 outside the US). Twenty-eight devices have been implanted worldwide...
January 2017: Seminars in Thoracic and Cardiovascular Surgery. Pediatric Cardiac Surgery Annual
https://www.readbyqxmd.com/read/27999712/fibrin-glue-injection-into-the-hematoma-cavity-for-refractory-chronic-subdural-hematoma-a-case-report
#14
Saiko Watanabe, Kenichi Amagasaki, Naoyuki Shono, Hiroshi Nakaguchi
BACKGROUND: Repeat burr hole irrigation and drainage has been effective in most cases of recurrent chronic subdural hematoma (CSDH), however, refractory cases require further procedures or other interventions. CASE DESCRIPTION: An 85-year-old male presented with left CSDH, which recurred five times. The hematoma was irrigated and drained through a left frontal burr hole during the first to third surgery and through a left parietal burr hole during the fourth and fifth surgery...
2016: Surgical Neurology International
https://www.readbyqxmd.com/read/27991023/-heart-transplantation-and-long-term-lvad-support-cost-effectiveness-model
#15
Ilona Szentmihályi, János Imre Barabás, Ágnes Bali, Gábor Kapus, Csilla Tamás, Balázs Sax, Endre Németh, Miklós Pólos, László Daróczi, Andrea Kőszegi, Chun Cao, Kálmán Benke, Péter Barnabás Kovács, Levente Fazekas, Zoltán Szabolcs, Béla Merkely, István Hartyánszky
Heart transplantation is a high priority project at Semmelweis University. In accordance with this, the funding of heart transplantation and mechanical circulatory support also constitutes an important issue. In this report, the authors discuss the creation of a framework with the purpose of comparing the cost-effectiveness of heart transplantation and artificial heart implantation. Our created framework includes the calculation of cost, using the direct allocation method, calculating the incremental cost-effectiveness ratio and creating a cost-effectiveness plane...
December 2016: Magyar Sebészet
https://www.readbyqxmd.com/read/27990844/artificial-heart-pumps-bridging-the-gap-between-science-technology-and-personalized-medicine-by-relational-medicine
#16
Federica Raia, Mario C Deng
In the US population of 300 million, 3 million have heart failure with reduced ejection fraction and 300,000 have advanced heart failure. Long-term mechanical circulatory support will, within the next decade, be recommended to 30,000 patients annually in the USA, 3000 undergo heart transplantation annually. What do these advances mean for persons suffering from advanced heart failure and their loved ones/caregivers? In this perspective article, we discuss - by exemplifying a case report of a 27-year-old man receiving a Total Artificial Heart - a practice concept of modern medicine that fully incorporates the patient's personhood perspective which we have termed Relational Medicine™...
January 2017: Future Cardiology
https://www.readbyqxmd.com/read/27990197/transcatheter-aortic-valve-implantation-for-treatment-of-aortic-valve-stenosis-a-health-technology-assessment
#17
(no author information available yet)
BACKGROUND: Surgical aortic valve replacement (SAVR) is the gold standard for treating aortic valve stenosis. It is a major operation that requires sternotomy and the use of a heart-lung bypass machine, but in appropriately selected patients with symptomatic, severe aortic valve stenosis, the benefits of SAVR usually outweigh the harms. Transcatheter aortic valve implantation (TAVI) is a less invasive procedure that allows an artificial valve to be implanted over the poorly functioning valve...
2016: Ontario Health Technology Assessment Series
https://www.readbyqxmd.com/read/27984313/electrical-stimulation-of-artificial-heart-muscle-a-look-into-the-electrophysiological-and-genetic-implications
#18
Mohamed A Mohamed, Jose F Islas, Robert J Schwartz, Ravi K Birla
Development of tissue-engineered hearts for treatment of myocardial infarction or biological pacemakers has been hindered by the production of mostly arrhythmic or in-synergistic constructs. Electrical stimulation (ES) of these constructs has been shown to produce tissues with greater twitch force and better adrenergic response. In order to further our understanding of the mechanisms underlying the effect of ES, we fabricated a bioreactor capable of delivering continuous or intermittent waveforms of various types to multiple constructs simultaneously...
December 13, 2016: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://www.readbyqxmd.com/read/27978952/prosthetic-heart-valve-thrombosis
#19
REVIEW
George D Dangas, Jeffrey I Weitz, Gennaro Giustino, Raj Makkar, Roxana Mehran
Although surgery was the mainstay of treatment for valvular heart disease, transcatheter valve therapies have grown exponentially over the past decade. Two types of artificial heart valve exist: mechanical heart valves (MHV), which are implanted surgically, and bioprosthetic heart valves (BHV), which can be implanted via a surgical or transcatheter approach. Whereas long-term anticoagulation is required to prevent thromboembolism after MHV replacement, its value in patients receiving BHVs is uncertain. Patients undergoing transcatheter BHV replacement are at risk for thromboembolism in the first few months, and recent data suggest that the risk continues thereafter...
December 20, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27935891/-rate-of-in-hospital-cardiovascular-complications-in-patients-with-postoperative-renal-dysfunction-after-surgical-myocardial-revascularization
#20
L V Kremneva, O V Abaturova, S V Shalaev
The study was aimed at revealing the factors associated with renal dysfunction having developed after coronary artery bypass grafting (CABG) and assessing the in-hospital cardiovascular complications rate amongst patients with postoperative renal dysfunction. The study included a total of 99 patients presenting with stable angina pectoris and having indications for CABG. The mean age of the patients amounted to 57±7 years, with the average duration of coronary artery disease (CAD) of 6±5.7 years. A multi-vessel lesion of coronary arteries was revealed in 69...
2016: Angiologii︠a︡ i Sosudistai︠a︡ Khirurgii︠a︡, Angiology and Vascular Surgery
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