Supriya Sharma, Pragnya Rao Donthineni, Geetha Iyer, James Chodosh, Maria Fideliz de la Paz, Quresh Maskati, Bhaskar Srinivasan, Shweta Agarwal, Sayan Basu, Swapna S Shanbhag
Bilateral corneal blindness with severe dry eye disease (DED), total limbal stem cell deficiency with underlying corneal stromal scarring and vascularization, combined with adnexal complications secondary to chronic cicatrizing conjunctivitis is a highly complex situation to treat. In such eyes, procedures such as penetrating keratoplasty alone or combined with limbal stem cell transplantation are doomed to fail. In these eyes, keratoprosthesis (Kpro) or an artificial cornea is the most viable option, eliminating corneal blindness even in eyes with autoimmune disorders such as Stevens-Johnson syndrome, ocular mucous membrane pemphigoid, Sjogren's syndrome, and nonautoimmune disorders such as chemical/thermal ocular burns, all of which are complex pathologies...
April 2023: Indian Journal of Ophthalmology