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Osteosarcoma of the ilium

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https://www.readbyqxmd.com/read/25621678/malignant-transformation-in-monostotic-fibrous-dysplasia-clinical-features-imaging-features-outcomes-in-10-patients-and-review
#1
REVIEW
Nan Qu, Weiwu Yao, Xiaojiang Cui, Huizhen Zhang
Malignant transformation in fibrous dysplasia (FD) is uncommon. The purpose of this study was to investigate clinical and imaging features, and outcomes of malignant transformation in monostotic FD.Data for 10 pathologically confirmed malignant transformations in monostotic FD from January 2005 to December 2013 were retrospectively reviewed. Patient data were recorded, and radiographs (n = 10), computed tomography (CT) (n = 5), magnetic resonance (MR) (n = 4), and bone scintigrams (n = 10) were evaluated for lesion location, margin, cortical destruction, marrow involvement, periosteal reaction, and soft tissue mass by 2 musculoskeletal radiologists with agreement by consensus...
January 2015: Medicine (Baltimore)
https://www.readbyqxmd.com/read/24887255/bone-malignancies-in-orthopaedic-hospital-igbobi-lagos-nigeria
#2
James J Adeniran, Eyesan U Samuel, Obalum C Dike, Salami O Olayinka, Olawepo Ayokunle, O E Nnodu, F B Abdulkareem
AIMS AND OBJECTIVES: To document the pattern of bone malignancies in a highly populated orthopaedic hospital in Lagos Nigeria; PATIENTS AND METHODS: A total of 21 cases of primary malignant bone tumours were studied. This comprised 12 cases of Osteosarcoma, 7 cases of Malignant Fibrous Histiocytoma (MFH) and 2 cases of Chondrosarcoma. Males (13) were affected more than females (8) giving a male to female ratio of 1.6 to 1. The age range was 7 to 45 years with a median age of 24 years...
March 2014: Nigerian Postgraduate Medical Journal
https://www.readbyqxmd.com/read/24844014/-allogeneic-bone-transplantation-for-pelvic-reconstruction-of-large-skeletal-defects-after-tumor-resection
#3
Wei Wang, Yan Wang, Wenzhi Bi, Jing Yang, Gang Han, Jinpeng Ia, Meng Xu, Guiqi Liu
OBJECTIVE: To investigate the short-term effectiveness of allogeneic bone transplantation for pelvic reconstruction of large skeletal defects after tumor resection. METHODS: Between January 2008 and November 2009, 9 patients with pelvic tumor were treated, and the clinical data were retrospectively analyzed. There were 1 male and 8 females with an average age of 36.1 years (range, 18-44 years). There were 5 cases of giant cell tumor of bone, 2 cases of chondrosarcoma, 1 case of malignant giant cell tumor of bone, and 1 case of Ewing sarcoma...
March 2014: Chinese Journal of Reparative and Reconstructive Surgery
https://www.readbyqxmd.com/read/24250275/the-use-of-iliac-stem-prosthesis-for-acetabular-defects-following-resections-for-periacetabular-tumors
#4
Massimiliano De Paolis, Alessio Biazzo, Carlo Romagnoli, Nikolin Alì, Sandro Giannini, Davide Maria Donati
INTRODUCTION: The management of pelvic tumors is a challenge for orthopaedic oncologists due to the complex anatomy of the pelvis and the need to have extensive exposure. Various reconstructive techniques have been proposed with poor functional results and a high percentage of complications. Our purpose is to determine the functional results and the rate of complications of iliac stem prosthesis for acetabular defects following resections for periacetabular tumors. MATERIALS AND METHODS: Between 1999 and 2012, 45 patients underwent pelvic resections for periacetabular bone tumors followed by reconstruction with stem cup prosthesis...
2013: TheScientificWorldJournal
https://www.readbyqxmd.com/read/24240323/imaging-appearances-and-clinical-outcome-following-sacrectomy-and-ilio-lumbar-reconstruction-for-sacral-neoplasia
#5
Marianna Thomas, A M Davies, A J Stirling, R J Grimer, M Grainger, Steven L J James
OBJECTIVE: Sacrectomy and ilio-lumbar reconstruction is an uncommonly performed complex surgical procedure for the treatment of sacral neoplasia. There are many challenges in the post-operative period including the potential for tumor recurrence, infection, and construct failure. We present our experience of this patient cohort and describe the complications and imaging appearances that can be encountered during the follow-up period. MATERIALS AND METHODS: Retrospective review of our Orthopaedic Oncology database was undertaken which has been collected over a 30-year period to identify patients that had undergone sacrectomy and ilio-lumbar reconstruction...
February 2014: Skeletal Radiology
https://www.readbyqxmd.com/read/23741219/postradiation-osteosarcoma-in-an-older-prostate-cancer-survivor-case-study-and-literature-review-with-emphasis-on-geriatric-principles
#6
Divya Gumber, Miriam Rodin, Tanya M Wildes
The aging population and the increasing number of cancer survivors will likely be associated with more second primary malignancies due to prior cancer treatment. Since the incidence of most cancers increases with age, these treatment-associated second malignancies will likely disproportionately impact older adults. Here, we present the case of a 78-year-old man with a history of localized prostate cancer treated with external beam radiation therapy 11 years prior, who developed osteosarcoma of the ilium. Geriatric screening showed a fit older male with few comorbidities, functional independence and no other geriatric syndromes...
May 2013: Case Reports in Oncology
https://www.readbyqxmd.com/read/23735291/femur-fibula-fillet-of-leg-chimeric-free-flap-for%C3%A2-sacral-pelvic-reconstruction
#7
Aisha J McKnight, Valerae O Lewis, Laurence D Rhines, Matthew M Hanasono
We describe the first case of a femur free flap in which we utilized the femur to restore pelvic ring continuity following a combined external hemipelvectomy-sacrectomy for cancer. We feel that the femur flap can be an important reconstructive tool for load-bearing bony reconstruction of the pelvis and spine when lower extremity amputation is required. We also utilized a fibula flap to stabilize the spine and a fillet of leg flap to provide soft tissue coverage as part of a chimeric femur-fibula-fillet of leg free flap from the same limb, allowing us to reconstruct a large, complex defect with "spare parts" from the discarded lower extremity, thereby totally eliminating any donor site morbidity...
December 2013: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/23427491/-combined-epiphyseal-preservation-and-autograft-bone-transfer-in-treatment-of-children-osteosarcoma
#8
Bin Fang, Chunzhi Yi, Hua Zhang, Qingwen Zhang, Yong Li, Qiushi Wei, Wei He, Zuoqing Zeng
OBJECTIVE: To investigate the clinical application and early results of combined epiphyseal preservation. METHODS: Between March 2010 and March 2011, and autograft bone transfer for limb salvage in children with osteosarcoma. 3 children with osteosarcoma were treated with epiphyseal preservation and autograft bone transfer. There were 1 boy and 2 girls with the age of 10-14 years. The disease duration was 2 weeks to 3 months. The tumors were rated as type II according to San-Julian radiological classification and as type IIB according to Enneking surgical classification...
January 2013: Chinese Journal of Reparative and Reconstructive Surgery
https://www.readbyqxmd.com/read/23392420/one-stage-total-en-bloc-sacrectomy-a-novel-technique-and-report-of-9-cases
#9
Wei Guo, Xiaodong Tang, Jie Zang, Tao Ji
STUDY DESIGN: Nine patients with malignant sacral tumor underwent 1-stage total sacrectomy. The oncological and functional results are analyzed. OBJECTIVE: To describe the surgical technique and evaluate the clinical outcome of the surgery. SUMMARY OF BACKGROUND DATA: Very few reports specifically address total sacrectomy, and the 2-stage procedure combining the anterior and posterior approach is the most common method used for treatment. METHODS: Between July 2007 and July 2010, 9 patients (7 males, 2 females; mean age, 33 yr; range, 13-59 yr) with malignant sacral tumor underwent 1-stage total sacrectomy the Peking University People's Hospital...
May 1, 2013: Spine
https://www.readbyqxmd.com/read/22995361/osteosarcoma-invasion-of-the-inferior-vena-cava-and-right-atrium
#10
Andreas F Mavrogenis, Andrea Angelini, Vasileios I Sakellariou, Evangelia Skarpidi, Pietro Ruggieri, Panayiotis J Papagelopoulos
We present a woman with chondroblastic osteosarcoma of the left ilium extending to the L4 epidural space and invading the inferior vena cava and right atrium, misdiagnosed as deep venous thrombosis. After neoadjuvant chemotherapy, two stage resection was planned. During the anterior approach, a mass in the left common iliac vein and inferior vena cava was found and tumor thromboembolism was diagnosed. Frozen sections showed chondroblastic osteosarcoma. The patient denied further surgery and had palliative intensity modulated radiation therapy...
2012: Journal of Surgical Orthopaedic Advances
https://www.readbyqxmd.com/read/22948770/iliosacral-resections-of-pelvic-malignant-tumors-and-reconstruction-with-nonvascular-bilateral-fibular-autografts
#11
Jin Wang, Qinglian Tang, Xianbiao Xie, Junqiang Yin, Zhiqiang Zhao, Zhibin Li, Changye Zou, Gang Huang, Jingnan Shen
BACKGROUND: Iliosacral resection of pelvic malignant tumors and subsequent reconstruction have tested the ingenuity of orthopedic oncologists because of the difficulty of oncological wide resection and the complex biomechanics of the sacroiliac joint render reconstruction challenging. This study compared the functional and surgical outcomes of a biological reconstruction technique with the lack of reconstruction following iliosacral resection. METHODS: Twenty-six consecutive cases with malignant iliac tumors involving the sacrum were retrospectively reviewed...
December 2012: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/22069978/-computer-aided-precise-resection-of-pelvic-tumor-and-function-reconstruction
#12
Huanwen Ding, Can Yi, Qiang Tu, Hong Wang, Huiliang Liu, Suolin Zeng, Bao Liu, Jianjian Shen, Yingjun Wang
OBJECTIVE: To investigate the value of computer-aided design (CAD) in defining the resection boundary, reconstructing the pelvis and hip in patients with pelvis tumors. METHODS: Between November 2006 and April 2009, 5 cases of pelvis tumors were treated surgically using CAD technology. There were 3 males and 2 females with an average age of 36.4 years (range, 24-62 years). The cause was osteosarcoma, giant cell tumor of bone, and angiosarcoma in 1 case, respectively, and chondrosarcoma in 2 cases...
October 2011: Chinese Journal of Reparative and Reconstructive Surgery
https://www.readbyqxmd.com/read/21914344/-clinicopathologic-features-of-primary-osteosarcoma-in-elderly-patients
#13
Yi Ding, Xiao-hui Niu, Yi Ding, Shu-qin Meng, Bao-yue Liu, Fa-jun Yang, Xia Huang, Xiao-yuan Huang
OBJECTIVE: To study the clinical manifestations, radiologic findings, pathologic diagnosis and differential diagnosis of primary osteosarcoma in elderly patients. METHODS: Twelve cases of primary osteosarcoma occurring in patients older than 60 years were encountered during the period from 1985 to 2010. The clinical manifestations, radiologic features and pathologic findings were studied and the follow-up data were analyzed. RESULTS: The sites of involvement included long bones (number = 7), ilium (number = 1), craniofacial bones (number = 2) and soft tissue (number = 2)...
June 2011: Zhonghua Bing Li Xue za Zhi Chinese Journal of Pathology
https://www.readbyqxmd.com/read/20508523/mandibular-reconstruction-using-nonvascularized-autogenous-bone-grafting
#14
REVIEW
Archie Morrison, James Brady
PURPOSE OF REVIEW: This paper will discuss reconstruction of the mandible with autogenous nonvascularized bone grafting. New developments in this area will be investigated by reviewing the most recent literature on this topic as compared with other techniques currently employed. With the advances of vascularized free flap reconstruction it is important to investigate the indication for nonvascularized techniques. RECENT FINDINGS: Replacement of a portion of the mandibular bone is a common procedure for patients undergoing ablative cancer surgery or for infection as well as temporomandibular joint replacement secondary to disease or trauma...
August 2010: Current Opinion in Otolaryngology & Head and Neck Surgery
https://www.readbyqxmd.com/read/20434041/resection-of-primary-sternal-osteosarcoma-and-reconstruction-with-homologous-iliac-bone-case-report
#15
Peng Ren, Jianguo Zhang, Xizeng Zhang
Primary sternal osteosarcoma is rare and has a poor prognosis. Here, we describe the case of a 44-year-old man with sternal osteosarcoma. He underwent subtotal sternectomy with partial resection of the bilateral ribs and left clavicle. Sternal reconstruction was performed with an iliac bone allograft, which was fixed by polyester suture. The patient had a normal postoperative course, followed by adjuvant chemotherapy. The allograft healed with correct integration, and have been no signs of recurrence and absorption during 14 years of follow-up...
April 2010: Journal of the Formosan Medical Association, Taiwan Yi Zhi
https://www.readbyqxmd.com/read/19690933/decancellation-sacral-osteotomy-in-iliosacral-tumor-resection-a-technique-for-precise-sacral-margins
#16
Yasser R Farid
En bloc resection of iliosacral sarcomas is a surgical challenge. There are substantial risks of inadequate margins, local recurrence, and nerve root loss when pelvic sarcomas involve sacral root canals and foramina. The decancellation technique uses principles similar to transpedicle decancellation in spinal deformity correction to perform the sacral osteotomy in iliosacral tumor resection. The technique aims at improving sacral margins and minimizing loss of neural function. We performed a decancellation osteotomy in five patients with sarcomas requiring difficult oblique or sagittal sacral osteotomies and selective root sacrifice...
May 2010: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/19416582/local-recurrence-of-osteosarcoma-after-17-years
#17
M J Welck, P D Gikas, P Pearce, R Bhumbra, T W R Briggs, S Cannon
The recurrence of osteosarcoma is rare. Local recurrence occurs in 4-10% of patients following effective treatment. So far, recurrences as late as 15 years have been reported in the literature. We report a unique case of local recurrence of intramedullary osteosarcoma 17 years from initial diagnosis and treatment. Regular long-term follow-up of patients with this diagnosis is crucial to ensure early detection and treatment of potential recurrences.
May 2009: Annals of the Royal College of Surgeons of England
https://www.readbyqxmd.com/read/19377403/-low-back-pain-the-relevance-of-a-symptom
#18
Ana Morais, Anabela Barcelos
Low back pain is one of the main reasons for doctor's appointment, and the motive of consultation of General Practitioners in 56% of cases. More than 85% of the patients who present to primary care physicians have low back pain that cannot reliably be attributed to a specific cause. In a minority of cases low back pain can be caused by a specific disorder, such as cancer. The authors describe a case of a 59-year-old woman with prolonged evolution low back pain which turned out to be a high grade osteossarcoma of the iliac bone...
January 2009: Acta Reumatológica Portuguesa
https://www.readbyqxmd.com/read/19330812/joint-preserving-limb-salvage-surgery-under-navigation-guidance
#19
Hwan Seong Cho, Joo Han Oh, Ilkyu Han, Han-Soo Kim
BACKGROUND: Recently, the navigation system has been introduced to orthopedic oncology. It can apply MRI and/or CT images to intraoperative visualization. We performed navigation-assisted limb salvage surgeries on patients with a malignant bone tumor of the metaphysis of the long bone or the iliac bone while preserving the adjacent joint. METHODS: When preoperative chemotherapy was estimated to be effective by imaging studies and the residual remaining epiphysis was expected to be more than 1 cm long after tumor resection with 1-2 cm of surgical margin, joint-preserving surgery was performed under navigation guidance...
September 1, 2009: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/19083646/calcaneus-replacement-after-total-calcanectomy-via-vascularized-pelvis-bone
#20
L A Kurvin, C Volkering, S B Kessler
Because of loss of function and chronic pain total calcanectomy is a serious impairment for the patient. There are few reports concerning replacement procedures using ribs [Brenner P, Zwipp H, Rammelt S. Vascularized double barrel ribs combined with free serratus anterior muscle transfer for homologous restoration of the hindfoot after calcanectomy. J Trauma-Injury Infect Crit Care 2000;49(2):331-5; Lin CH, Wei FC, Levin LS, Su JI. Free composite serratus anterior and rib flaps for tibial composite bone and soft-tissue defect...
2008: Foot and Ankle Surgery: Official Journal of the European Society of Foot and Ankle Surgeons
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