Lorenz Wernisch, Tristan Edwards, Antonin Berthon, Olivier Tessier-Lariviere, Elvijs Sarkans, Myrta Stoukidi, Pascal Fortier-Poisson, Max Pinkney, Michael Thornton, Catherine Hanley, Susannah Lee, Joel Jennings, Ben Appleton, Philip Garsed, Bret Patterson, Will Buttinger, Samuel Gonshaw, Matjaz Jakopec, Sudhakaran Shunmugam, Jorin Mamen, Aleksi Tukiainen, Guillaume Lajoie, Oliver Armitage, Emil Hewage
In bioelectronic medicine, neuromodulation therapies induce neural signals to the brain or organs, modifying their function. Stimulation devices capable of triggering exogenous neural signals using electrical waveforms require a complex and multi-dimensional parameter space to control such waveforms. Determining the best combination of parameters (waveform optimization or dosing) for treating a particular patient's illness is therefore challenging. Comprehensive parameter searching for an optimal stimulation effect is often infeasible in a clinical setting due to the size of the parameter space...
March 13, 2024: Journal of Neural Engineering