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https://www.readbyqxmd.com/read/29470370/examining-diagnosing-and-treating-benign-anorectal-conditions
#1
Priscilla Marsicovetere
Anorectal pain and discomfort are common complaints in the general population, and can stem from a number of possible causes. Often, the complaints present in the primary care setting and can be adequately evaluated, diagnosed, and treated without the need for referral to a colorectal specialist. Proper evaluation and diagnosis can result in prompt, effective patient care. Recognition of red flags should prompt immediate referral to a colorectal specialist for further evaluation.
March 2018: JAAPA: Official Journal of the American Academy of Physician Assistants
https://www.readbyqxmd.com/read/29465701/optimizing-screening-for-sexually-transmitted-infections-in-men-using-self-collected-swabs-a-systematic-review
#2
Nicholas Yared, Keith Horvath, Oluwaseun Fashanu, Ran Zhao, Jason Baker, Shalini Kulasingam
BACKGROUND: Sexually transmitted infection (STI) rates are increasing in the U.S. while funding for prevention and treatment programs has declined. Sample self-collection for STI testing in men may provide an acceptable, easy, rapid and potentially cost-effective method for increasing diagnosis and treatment of STIs. METHODS: We conducted a systematic review of articles assessing self-collection of anal, oral, or genital swab samples among adult men for detection of STIs and/or human papillomavirus (HPV)-related dysplasia...
October 6, 2017: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/29465653/clinical-characteristics-of-anorectal-mycoplasma-genitalium-infection-and-microbial-cure-in-men-who-have-sex-with-men
#3
Jason J Ong, Ei Aung, Tim R H Read, Christopher K Fairley, Suzanne M Garland, Gerald Murray, Marcus Y Chen, Eric P F Chow, Catriona S Bradshaw
BACKGROUND: We report clinical characteristics of proctitis caused solely by Mycoplasma genitalium(MG), compared with chlamydia and gonococcus. We determined the proportions cured with first-line (azithromycin) and second-line antimicrobials (moxifloxacin, pristinamycin). METHODS: 166 patients attending Melbourne Sexual Health Centre from 2012 to 2016 with symptoms of proctitis were tested for MG, Chlamydia trachomatis and Neisseria gonorrhoeae. Demographic characteristics, sexual behaviours, clinical symptoms and signs were recorded...
January 18, 2018: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/29465648/associations-between-anorectal-chlamydia-and-oro-anal-sex-or-saliva-use-as-a-lubricant-for-anal-sex-a-cross-sectional-survey
#4
Vincent J Cornelisse, Christopher K Fairley, Tim R H Read, David Lee, Sandra Walker, Jane S Hocking, Marcus Y Chen, Catriona S Bradshaw, Eric P F Chow
BACKGROUND: Receptive condomless anal sex is a known risk factor for anorectal chlamydia, but it remains unclear whether oro-anal sex practices also contribute. We aimed to determine whether oro-anal sex ("rimming"), fingering or the use of saliva as anal lubricant are risk factors for anorectal chlamydia among men who have sex with men (MSM). METHODS: This cross-sectional study was conducted at Melbourne Sexual Health Centre from July 2014 to June 2015...
January 30, 2018: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/29464583/intestinal-involvement-in-systemic-sclerosis-a-clinical-review
#5
REVIEW
Lazaros I Sakkas, Theodora Simopoulou, Dimitrios Daoussis, Stamatis-Nick Liossis, Spyros Potamianos
Systemic sclerosis (SSc) is a chronic systemic disease characterized by microvasculopathy, autoantibodies, and extensive fibrosis. Intestinal involvement is frequent in SSc and represents a significant cause of morbidity. The pathogenesis of intestinal involvement includes vascular damage, nerve dysfunction, smooth muscle atrophy, and fibrosis, causing hypomotility, which leads to small intestinal bacterial overgrowth (SIBO), malabsorption, malnutrition, diarrhea, pseudo-obstruction, constipation, pneumatosis intestinalis, and fecal incontinence...
February 21, 2018: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/29464273/-perianal-inflammatory-diseases-classification-and-imaging
#6
REVIEW
A-O Schäfer
During the past 30 years, classifications and scoring systems have been developed in order to evaluate and objectify the degree and activity of anorectal fistulas. Only a few of these disease-specific instruments have been adopted into daily clinical routine. Generally, clinicians tend to use global medical judgement rather than numeric activity indices, which often seem complex and time consuming. Activity scores in Crohn disease, however, appeared to be very useful in clinical trials regarding evaluation of therapy response...
February 20, 2018: Der Radiologe
https://www.readbyqxmd.com/read/29460228/prevalence-of-asymptomatic-sexually-transmitted-infections-in-hiv-positive-men-who-have-sex-with-men-in-germany-results-of-a-multicentre-cross-sectional-study
#7
Christoph D Spinner, Christoph Boesecke, Cornelius Jordan, Christoph Wyen, Tim Kümmerle, Gaby Knecht, Stefan Scholten, Alexander Zink, Ivanka Krznaric, Sebastian Noe
PURPOSE: Sexually transmitted infections (STIs) occur frequently in risk populations. Hereby, the role of screening-programmes remains controversial. Our study aimed to determine the prevalence of STI infections in HIV-positive men-who-have-sex-with-men (MSM). METHODS: We enrolled asymptomatic, HIV-MSM in a prospective cross-sectional study from February to August 2016 at seven German HIV-centres. All subjects were screened for Treponema-pallidum (TP) and hepatitis-B/C-infection...
February 19, 2018: Infection
https://www.readbyqxmd.com/read/29454526/predicting-sexual-problems-in-young-adults-with-an-anorectal-malformation-or-hirschsprung-disease
#8
M J Witvliet, S van Gasteren, D van den Hondel, E Hartman, Lwe van Heurn, Afw van der Steeg
AIM: The aim of this study was to examine the prevalence of sexual dysfunction and distress and to assess whether sexual functioning could be predicted by psychosocial factors in childhood and adolescence in patients with an anorectal malformation or Hirschsprung disease. MATERIAL AND METHODS: In 1998 patients completed a psychosocial questionnaire: The Self-Perception profile. To assess the prevalence of sexual distress and sexual functioning in adulthood (2015) the Female Sexual Function Index (FSFI), The Female Sexual Distress Scale (FSDS) and the International Index of Erectile Functioning (IIEF) were used...
January 31, 2018: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/29451592/prevalence-of-streptococcus-agalactiae-colonization-in-pregnant-women-from-the-18th-health-region-of-paran%C3%A3-state
#9
Simone Cristina Castanho Sabaini de Melo, Aline Balandis Costa, Flávia Teixeira Ribeiro da Silva, Natália Maria Maciel Guerra Silva, Cristiano Massao Tashima, Rosilene Fressatti Cardoso, Rúbia Andreia F de Pádua, Isolde Previdelli, Maria Dalva de Barros Carvalho, Sandra Marisa Pelloso
Introduction The aim of this study was to determine the prevalence of GBS colonization in pregnant women in a public health service. Methods A study of 496 pregnant women at 35-37 gestational weeks was conducted from September 2011 to March 2014 in 21 municipalities of the 18th Health Region of Paraná State. Vaginal and anorectal samples of each woman were plated on sheep blood agar, and in HPTH and Todd-Hewitt enrichment broths. Results Of the 496 pregnant women, 141 (28.4%) were positive for GBS based on the combination of the three culture media with vaginal and anorectal samples...
2018: Revista do Instituto de Medicina Tropical de São Paulo
https://www.readbyqxmd.com/read/29447025/anal-sphincter-dysfunction-in-patients-treated-with-primary-radiotherapy-for-anal-cancer-a-study-with-the-functional-lumen-imaging-probe
#10
Susanne Haas, Pia Faaborg, Donghua Liao, Søren Laurberg, Hans Gregersen, Lilly Lundby, Peter Christensen, Klaus Krogh
BACKGROUND: Sphincter-sparing radiotherapy or chemoradiation are standard treatments for patients with anal cancer. The ultimate treatment goal is full recovery from anal cancer with preserved anorectal function. Unfortunately, long-term survivors often suffer from severe anorectal symptoms. The aim of the present study was to characterize changes in anorectal physiology after radiotherapy for anal cancer. METHOD: We included 13 patients (10 women, age 63.4 ± 1...
February 15, 2018: Acta Oncologica
https://www.readbyqxmd.com/read/29446703/use-of-the-5-mm-endoscopic-stapler-for-ligation-of-fistula-in-laparoscopic-assisted-repair-of-anorectal-malformation
#11
Bethany J Slater, Saundra Kay, Steven S Rothenberg
OBJECTIVE: Laparoscopic anorectoplasty (LARRP) for the treatment of select anorectal malformations has gained popularity due to enhanced visualization of the fistula and the ability to place the rectum within the sphincter complex while minimizing division of muscles and the perineal incision. However, given the technical challenges and reported complications of ligation, a number of techniques have been described, including using clips, suture ligation, endoloops, or division without closure...
February 15, 2018: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/29439660/the-impact-of-down-regulated-sk3-expressions-on-hirschsprung-disease
#12
Gunadi, Mukhamad Sunardi, Nova Yuli Prasetyo Budi, Alvin Santoso Kalim, Kristy Iskandar, Andi Dwihantoro
BACKGROUND: Some Hirschsprung's disease (HSCR) patients showed persistent bowel symptoms following an appropriately performed pull-through procedure. The mechanism is presumed to be down-regulated small-conductance calcium-activated potassium channel 3 (SK3) expression in the HSCR ganglionic intestines. We aimed to investigate the SK3 expression's impact in HSCR patients after a properly performed pull-through surgery in an Indonesian population, a genetically distinct group within Asia...
February 13, 2018: BMC Medical Genetics
https://www.readbyqxmd.com/read/29434418/pelvic-floor-morphometric-differences-in-elderly-women-with-or-without-urinary-incontinence
#13
Sarah Fradet, Mélanie Morin, Jennifer Kruger, Chantale Dumoulin
Purpose: Urinary incontinence (UI) affects as many as 50% of women aged 60 years and older, but UI pathophysiology, specifically in elderly women, remains unclear. A better understanding of morphometric differences between continent and urinary incontinent elderly women is needed to improve the effectiveness of conservative treatment approaches. We hypothesized that morphometric differences in the pelvic floor muscles (PFM) among elderly women with and without UI could be observed using three- and four-dimensional (3D/4D) transperineal ultrasound (TPU) imaging...
2018: Physiotherapy Canada. Physiothérapie Canada
https://www.readbyqxmd.com/read/29433086/potential-roles-for-glucagon-like-peptide-1-7-36-amide-and-cholecystokinin-in-anorectic-response-to-the-trichothecene-mycotoxin-t-2-toxin
#14
Wenda Wu, Kun Sheng, Xinglian Xu, Haibin Zhang, Guanghong Zhou
Anorexia is a hallmark of animal and human exposed to T-2 toxin, a most poisonous trichothecene mycotoxins contaminating various cereal grains including wheat, corn and barley. Although this adverse effect has been well characterized in several animal species, the underlying mechanisms are unclear. The goal for this study was to elucidate the roles of two gut satiety hormones, glucagon-like peptide-17-36amide (GLP-1) and cholecystokinin (CCK) in T-2 toxin-evoked anorectic response using a mouse anorexia bioassay...
February 9, 2018: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/29428016/suprapubic-midline-extraperitoneal-approach-for-widespread-retroperitoneal-abscess-originating-from-anorectal-abscess
#15
Oktay Aydin, Faruk Pehlivanlı, Gökhan Karaca, Gülçin Aydın, İsmail Özler, Çağatay Daphan
No abstract text is available yet for this article.
January 1, 2018: American Surgeon
https://www.readbyqxmd.com/read/29425507/supraphysiologic-administration-of-gdf11-induces-cachexia-in-part-by-upregulating-gdf15
#16
Juli E Jones, Samuel M Cadena, Chenguang Gong, Xiaomei Wang, Zhiping Chen, Sharon X Wang, Chad Vickers, Hong Chen, Estelle Lach-Trifilieff, John R Hadcock, David J Glass
The age-related effects of GDF11 have been a subject of controversy. Here, we find that elevated GDF11 causes signs of cachexia in mice: reduced food intake, body weight, and muscle mass. GDF11 also elicited a significant elevation in plasma Activin A, previously shown to contribute to the loss of skeletal muscle. The effects of GDF11 on skeletal muscle could be reversed by administration of antibodies to the Activin type II receptors. In addition to the effects on muscle, GDF11 increased plasma GDF15, an anorectic agent...
February 6, 2018: Cell Reports
https://www.readbyqxmd.com/read/29423308/the-anorectal-exam-is-unnecessary
#17
Ralph J Marino
No abstract text is available yet for this article.
2018: Spinal Cord Series and Cases
https://www.readbyqxmd.com/read/29420449/rising-chlamydia-and-gonorrhoea-incidence-and-associated-risk-factors-among-female-sex-workers-in-australia-a-retrospective-cohort-study
#18
Denton Callander, Hamish McManus, Rebecca Guy, Margaret Hellard, Catherine C O'Connor, Christopher K Fairley, Eric P F Chow, Anna McNulty, David A Lewis, Christopher Carmody, Heather-Marie A Schmidt, Jules Kim, Basil Donovan
BACKGROUND: Female sex workers in Australia have achieved some of the lowest documented prevalences of human immunodeficiency virus (HIV) and other sexually transmissible infections globally but rates overall are increasing in Australia and warrant closer investigation. METHODS: We constructed a retrospective cohort using repeat testing data extracted from a network of 42 sexual health clinics. Poisson and Cox regression were used to determined trends in incidence and risk factors for HIV, chlamydia, gonorrhoea, and infectious syphilis among female sex workers...
March 2018: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/29420445/frequency-of-nucleic-acid-amplification-test-positivity-among-men-who-have-sex-with-men-returning-for-a-test-of-cure-visit-7-to-30-days-after-treatment-of-laboratory-confirmed-neisseria-gonorrhoeae-infection-at-2-public-sexual-health-clinics-new-york-city-2013
#19
Ebiere Okah, Emily F Westheimer, Kelly Jamison, Julia A Schillinger
BACKGROUND: The Centers for Disease Control and Prevention 2015 Sexually Transmitted Disease Treatment Guidelines recommend that clinicians consider cephalosporin treatment failure in patients who deny interval sexual exposure and are nucleic acid amplification test (NAAT) positive for Neisseria gonorrhoeae (NG) at least 7 days after adequate treatment. We evaluate the real-world implications of the interval the Centers for Disease Control and Prevention recommends for a NAAT test-of-cure (TOC), by ascertaining the frequency of NG NAAT positivity at different anatomic sites among men who have sex with men (MSM) at TOC 7 to 30 days after treatment...
March 2018: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/29420431/challenges-in-transition-of-care-for-patients-with-anorectal-malformations-a-systematic-review-and-recommendations-for-comprehensive-care
#20
Sarah B Cairo, Alessandra Gasior, Michael D Rollins, David H Rothstein
BACKGROUND: Anorectal malformations are one of the most common congenital intestinal anomalies affecting newborns. Despite advances in neonatal care and surgical techniques, many patients with a history of anorectal malformations are affected by long-term challenges involving bowel and bladder dysfunction, sexual dysfunction, and psychosocial issues. These outcomes or challenges are additionally exacerbated by the lack of a structured transition of care from the pediatric to the adult setting...
March 2018: Diseases of the Colon and Rectum
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