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https://www.readbyqxmd.com/read/29299773/a-comparative-epidemiological-study-of-acute-renal-colic-presentations-to-emergency-departments-in-doha-qatar-and-melbourne-australia
#1
Sameer A Pathan, Biswadev Mitra, Zain A Bhutta, Isma Qureshi, Elle Spencer, Asmaa A Hameed, Sana Nadeem, Ramsha Tahir, Shahzad Anjum, Peter A Cameron
BACKGROUND: This study aimed to compare the epidemiology, clinical presentations, management, and outcomes of renal colic presentations in two major academic centers from geographically diverse populations: Qatar (a country in the Afro-Asian stone belt) and South-Eastern Australia (not within a stone belt). METHODS: We undertook a retrospective cohort study of patients with renal colic who presented to the Hamad General Hospital Emergency Department (HGH-ED), Qatar, and The Alfred ED, Melbourne, Australia, during a period of 1 year from August 1, 2012, to July 31, 2013...
January 3, 2018: International Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29290168/the-economic-burden-of-acpa-positive-status-among-patients-with-rheumatoid-arthritis
#2
Jason Shafrin, Mahlet Gizaw Tebeka, Kwanza Price, Chad Patel, Kaleb Michaud
BACKGROUND: Anticitrullinated protein antibodies (ACPAs) are serological biomarkers associated with early, rapidly progressing rheumatoid arthritis (RA), including more severe disease and joint damage. ACPA testing has become a routine tool for RA diagnosis and prognosis. Furthermore, treatment efficacy has been shown to vary by ACPA-positive status. However, it is not clear if the economic burden of patients with RA varies by ACPA status. OBJECTIVE: To determine if the economic burden of RA varies by patient ACPA status...
January 2018: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/29246210/rates-and-risk-factors-associated-with-hospitalization-for-pneumonia-with-icu-admission-among-adults
#3
Aaron D Storms, Jufu Chen, Lisa A Jackson, James D Nordin, Allison L Naleway, Jason M Glanz, Steven J Jacobsen, Eric S Weintraub, Nicola P Klein, Paul M Gargiullo, Alicia M Fry
BACKGROUND: Pneumonia poses a significant burden to the U.S. health-care system. However, there are few data focusing on severe pneumonia, particularly cases of pneumonia associated with specialized care in intensive care units (ICU). METHODS: We used administrative and electronic medical record data from six integrated health care systems to estimate rates of pneumonia hospitalizations with ICU admissions among adults during 2006 through 2010. Pneumonia hospitalization was defined as either a primary discharge diagnosis of pneumonia or a primary discharge diagnosis of sepsis or respiratory failure with a secondary diagnosis of pneumonia in administrative data...
December 16, 2017: BMC Pulmonary Medicine
https://www.readbyqxmd.com/read/29231162/evaluation-of-clinical-outcomes-among-nonvalvular-atrial-fibrillation-patients-treated-with-rivaroxaban-or-warfarin-stratified-by-renal%C3%A2-function%C3%A2
#4
Matthew R Weir, Lloyd Haskell, Jeffrey S Berger, Veronica Ashton, François Laliberté, Concetta Crivera, Kip Brown, Patrick Lefebvre, Jeffrey Schein
BACKGROUND: Renal dysfunction increases the risk of thromboembolic and bleeding events in patients with nonvalvular atrial fibrillation (NVAF). MATERIALS AND METHODS: Adult NVAF patients with ≥ 6 months prior to first warfarin or rivaroxaban dispensing were selected from the IMS Health Real-World Data Adjudicated Claims database (05/2011 - 06/2015) with electronic medical records. Ischemic stroke events, thromboembolic events (venous thromboembolism, myocardial infarction, or ischemic stroke), and major bleeding events were compared between patients by renal function identified by 1) relevant ICD-9-CM diagnosis codes and 2) estimated creatinine clearance (eCrCl)...
December 12, 2017: Clinical Nephrology
https://www.readbyqxmd.com/read/29172973/ezetimibe-use-and-ldl-c-goal-achievement-a-retrospective-database-analysis-of-patients-with-clinical-atherosclerotic-cardiovascular-disease-or-probable-heterozygous-familial-hypercholesterolemia
#5
Joseph Menzin, Jyoti Aggarwal, Brian Boatman, Jeffrey Yu, Kevin Stern, David J Harrison, Jeetvan G Patel
BACKGROUND: Ezetimibe is recommended by clinical practice guidelines as a second-line therapy for lowering low-density lipoprotein cholesterol (LDL-C) levels, but little is known about its use and effectiveness in real-world populations. OBJECTIVE: To understand the real-world impact of adding or switching to ezetimibe on LDL-C goal achievement in patients with clinical atherosclerotic cardiovascular disease (ASCVD) and/or heterozygous familial hypercholesterolemia (HeFH)...
December 2017: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/29170940/association-of-autism-spectrum-disorders-and-inflammatory-bowel-disease
#6
Maunoo Lee, Jayasree Krishnamurthy, Apryl Susi, Carolyn Sullivan, Gregory H Gorman, Elizabeth Hisle-Gorman, Christine R Erdie-Lalena, Cade M Nylund
Autism spectrum disorders (ASD) and inflammatory bowel disease (IBD) both have multifactorial pathogenesis with an increasing number of studies demonstrating gut-brain associations. We aim to examine the association between ASD and IBD using strict classification criteria for IBD. We conducted a retrospective case-cohort study using records from the Military Health System database with IBD defined as having one encounter with an ICD-9-CM diagnostic code for IBD and at least one outpatient prescription dispensed for a medication to treat IBD...
November 23, 2017: Journal of Autism and Developmental Disorders
https://www.readbyqxmd.com/read/29155253/the-association-of-inflammatory-bowel-disease-and-immediate-postoperative-outcomes-following-lumbar-fusion
#7
Joseph E Tanenbaum, Stephanie T Kha, Edward C Benzel, Michael P Steinmetz, Thomas E Mroz
BACKGROUND CONTEXT: The United States Centers for Disease Control estimates the prevalence of inflammatory bowel disease (IBD) at over 3.1 million people. As diagnostic techniques and treatment options for IBD improve, the prevalence of IBD is expected to increase. For spine surgeons, patients with IBD have a unique complication profile because IBD patients may present with poor nutritional status and because the medications used to manage IBD have been associated with poor vertebral bone mineralization and immunosuppression...
November 15, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/29152443/psychiatric-comorbidities-and-outcomes-in-epilepsy-patients-an-insight-from-a-nationwide-inpatient-analysis-in-the-united-states
#8
Rikinkumar S Patel, Ahmed Elmaadawi, Zeeshan Mansuri, Mandeep Kaur, Kaushal Shah, Suhayl Nasr
Background Psychiatric comorbidities in epilepsy impose significant burdens on patients and their families. It affects their quality of life and medical care and results in cost increases. This study reports the impact of various psychiatric comorbidities in epilepsy patients regarding hospital outcomes and in-hospital mortality. Methods We used the Nationwide Inpatient Sample (NIS) from the Healthcare Cost and Utilization Project (HCUP) from years 2013-2014. We identified epilepsy as the primary diagnosis and psychiatric comorbidities, namely, alcohol abuse, depression, drug abuse, and psychosis, using validated International Classification of Diseases, 9th Revision, Clinical Modification (ICD--9--CM) codes...
September 14, 2017: Curēus
https://www.readbyqxmd.com/read/29135667/nationwide-analysis-of-femoral-neck-fractures-in-elderly-patients-a-receding-tide
#9
Derek G Ju, Sean S Rajaee, James Mirocha, Carol A Lin, Charles N Moon
BACKGROUND: Geriatric femoral neck fractures are associated with substantial morbidity and medical cost. We evaluated the incidence and management trends of femoral neck fractures in recent years in the U.S. METHODS: Patient data from 2003 through 2013 were obtained from the Nationwide Inpatient Sample database. Femoral neck fractures in patients ≥65 years old were identified and grouped using the International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) procedure codes for internal fixation, hemiarthroplasty, or total hip arthroplasty (THA)...
November 15, 2017: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/29125368/societal-burden-of-cluster-headache-in-the-united-states-a-descriptive-economic-analysis
#10
Janet H Ford, Damion Nero, Gilwan Kim, Bong Chul Chu, Robert Fowler, Jonna Ahl, James M Martinez
AIM: To estimate direct and indirect costs in patients with a diagnosis of cluster headache in the US. METHODS: Adult patients (18 - 64 years of age) enrolled in the Marketscan Commercial and Medicare Databases with ≥ 2 non-diagnostic outpatient (≥ 30 days apart between the two outpatient claims) or ≥ 1 inpatient diagnoses of cluster headache (ICD-9-CM code 339.00, 339.01, or 339.02) between January 1, 2009 and June 30, 2014, were included in the analyses...
November 10, 2017: Journal of Medical Economics
https://www.readbyqxmd.com/read/29121921/transcatheter-aortic-valve-implantation-and-surgical-aortic-valve-replacement-among-hospitalized-patients-with-and-without-type-2-diabetes-mellitus-in-spain-2014-2015
#11
Manuel Mendez-Bailon, Noel Lorenzo-Villalba, Nuria Muñoz-Rivas, Jose Maria de Miguel-Yanes, Javier De Miguel-Diez, Josep Comín-Colet, Valentin Hernandez-Barrera, Rodrigo Jimenez-Garcia, Ana Lopez-de-Andres
BACKGROUND: Type 2 diabetes mellitus (T2DM) is strongly related to the in-hospital and short-term prognosis in patients with cardiovascular diseases needing surgical or invasive interventions. How T2DM might influence the treatment of aortic stenosis (AS) has not been completely elucidated for surgical aortic valve replacement (SAVR) or transcatheter aortic valve implantation (TAVI). The aims of this study were: (1) to describe the use of aortic valve replacement procedures (TAVI and SAVR) among hospitalized patients with and without T2DM; and (2) to identify factors associated with in hospital mortality (IHM) among patients undergoing these procedures...
November 9, 2017: Cardiovascular Diabetology
https://www.readbyqxmd.com/read/29108662/hospital-length-of-stay-and-cost-burden-of-hiv-tuberculosis-and-hiv-tuberculosis-coinfection-among-pregnant-women-in-the-united-states
#12
Adeola Falana, Vanessa Akpojiyovwi, Esther Sey, Andika Akpaffiong, Olive Agumbah, Samara Chienye, Jamie Banks, Erin Jones, Kiara K Spooner, Jason L Salemi, Omonike A Olaleye, Sherri D Onyiego, Hamisu M Salihu
BACKGROUND: We sought to determine hospital length of stay (LOS) and cost burden associated with hospital admissions among pregnant women with HIV monoinfection, tuberculosis (TB) monoinfection, or HIV-TB coinfection in the United States. METHODS: Analysis covered the period from 2002-2014 using data from the Nationwide Inpatient Sample. Relevant ICD-9-CM codes were used to determine HIV and TB status. Costs associated with hospitalization were calculated and adjusted to 2010 dollars using the medical care component of the Consumer Price Index...
November 3, 2017: American Journal of Infection Control
https://www.readbyqxmd.com/read/29095419/emergency-department-burden-of-nausea-and-vomiting-associated-with-cannabis-use-disorder-us-trends-from-2006-to-2013
#13
Andrea Bollom, Jasmine Austrie, William Hirsch, Judy Nee, Daniel Friedlander, Johanna Iturrino, Sarah Ballou, Anthony Lembo
BACKGROUND AND AIMS: Chronic cannabis use is associated with nausea and vomiting that may lead to emergency department (ED) visits, multiple diagnostic tests, and procedures. The aim of this study was to analyze recent trends in ED visits for vomiting associated with cannabis use disorder between 2006 and 2013. METHODS: Data were obtained from the National Emergency Department Sample records in which vomiting (ICD-9-CM codes 787.01, 787.03, and 536.2) was a primary diagnosis in combination with cannabis abuse or dependence (304...
October 31, 2017: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/29083972/inhaled-corticosteroid-containing-treatment-escalation-and-outcomes-for-patients-with-asthma-in-a-u-s-health-care-organization
#14
Lindsay G S Bengtson, Yanni Yu, Weijia Wang, Feng Cao, Erin M Hulbert, Ryan Wolbeck, Caitlin A Elliott, Ami R Buikema
BACKGROUND: Asthma is a common disorder that affects approximately 8% of the U.S. POPULATION: Treatment guidelines indicate inhaled corticosteroids (ICS) as the mainstay treatment, yet poor asthma control is common among ICS-treated patients. Treatment escalation (ICS dose increase and other controller therapy add-ons) is used to manage symptoms. Real-world studies of postescalation outcomes may inform treatment decisions. OBJECTIVES: To (a) describe characteristics and treatment patterns among asthma patients who escalated treatment and (b) assess outcomes (exacerbations, uncontrolled asthma, and health care resource utilization [HCRU]) after escalation...
November 2017: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/29068610/seizure-risk-associated-with-antidepressant-treatment-among-patients-with-depressive-disorders-a-population-based-case-crossover-study
#15
Chi-Shin Wu, Hsin-Yen Liu, Hui-Ju Tsai, Shi-Kai Liu
OBJECTIVE: To assess the risk of seizure associated with antidepressant use among patients with depressive disorders. METHODS: Individuals visiting the emergency department or hospitalized because of new-onset seizure (ICD-9-CM diagnostic code 345 or 780.3; our primary study outcome) after receiving antidepressants for depressive disorders, were identified from a Taiwanese total population health insurance database. Using a case-crossover study design, relative risk of antidepressant-related seizure was estimated by comparing the rates of antidepressant exposure during the case periods vs control periods...
October 24, 2017: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/29066925/estimating-the-prevalence-of-generalized-and-partial-lipodystrophy-findings-and-challenges
#16
Elaine Chiquette, Elif A Oral, Abhimanyu Garg, David Araújo-Vilar, Praveen Dhankhar
BACKGROUND: Lipodystrophy (LD; non-human immunodeficiency virus [HIV]-associated) syndromes are a rare body of disorders for which true prevalence is unknown. Prevalence estimates of rare diseases are important to increase awareness and financial resources. Current qualitative and quantitative estimates of LD prevalence range from ~0.1 to 90 cases/million. We demonstrate an approach to quantitatively estimate LD prevalence (all, generalized, and partial) through a search of 5 electronic medical record (EMR) databases and 4 literature searches...
2017: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy
https://www.readbyqxmd.com/read/29051548/gastrointestinal-hemorrhage-after-spontaneous-subarachnoid-hemorrhage-a-single-center-cohort-study
#17
Shang-Po Wang, Yu-Hua Huang
Spontaneous subarachnoid hemorrhage (SAH) is a devastating disease, and gastrointestinal hemorrhage is one of several potential complications of acute strokes. We aim to analyze its prevalence, risk factors, and association with in-hospital prognosis following SAH. A total of 1047 adult patients with a primary diagnosis of spontaneous SAH were retrospectively enrolled. We retrieved medical information from the administrative database utilizing diagnostic and procedure codes of the International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM)...
October 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28981480/retention-in-medical-care-among-insured-children-with-diagnosed-hiv-infection-united-states-2010-2014
#18
Mary R Tanner, Tim Bush, Steven R Nesheim, Paul J Weidle, Kathy K Byrd
In 2014, an estimated 2,477 children aged <13 years were living with diagnosed human immunodeficiency virus (HIV) infection in the United States (1). Nationally, little is known about how well children with a diagnosis of HIV infection are retained in medical care. CDC analyzed insurance claims data to evaluate retention in medical care for children in the United States with a diagnosis of HIV infection. Data sources were the 2010-2014 MarketScan Multi-State Medicaid and MarketScan Commercial Claims and Encounters databases...
October 6, 2017: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/28972929/risks-of-road-injuries-in-patients-with-bipolar-disorder-and-associations-with-drug-treatments-a-population-based-matched-cohort-study
#19
Vincent Chin-Hung Chen, Yao-Hsu Yang, Chuan-Pin Lee, Jennifer Wong, Lynn Ponton, Yena Lee, Roger S McIntyre, Kuo-You Huang, Shu-I Wu
OBJECTIVE: Using a nation-wide, population-based dataset, we aimed to investigate the risk of road injury among individuals with bipolar disorder (BD) compared to individuals without BD. In addition, we investigated the putative moderating effects of prescription for lithium, anticonvulsants, antidepressants, and/or first- or second-generation antipsychotic agents on the association between BD and risk of road injury. METHOD: As part of an16-year longitudinal cohort study, we compared the risk of road injuries among study subjects aged 16 and above with a diagnosis of BD, with ten age- and sex-matched sample of individuals without BD...
September 23, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28949045/the-impact-of-diabetes-mellitus-and-hepatitis-b-virus-co-infection-on-patients-with-chronic-hepatitis-c-a-territory-wide-cohort-study
#20
Shreenidhi Subramaniam, Vincent Wai-Sun Wong, Yee-Kit Tse, Terry Cheuk-Fung Yip, Henry Lik-Yuen Chan, Grace Lai-Hung Wong
BACKGROUND & AIM: Studies have demonstrated a higher prevalence of diabetes mellitus (DM) in patients with chronic hepatitis C (CHC). Furthermore, co-infection with hepatitis B virus (HBV) is common due to its endemicity in Asian-Pacific regions. We aimed to investigate the impact of DM and HBV co-infection on the clinical outcomes in Chinese CHC patients. METHODS: We conducted a territory-wide cohort study using the database from Hospital Authority, the sole public medical service provider in Hong Kong...
September 26, 2017: Journal of Gastroenterology and Hepatology
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