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https://www.readbyqxmd.com/read/29040592/the-association-between-igf-i-and-igfbp-3-and-incident-diabetes-in-an-older-population-of-men-and-women-in-the-cardiovascular-health-study
#1
Chino S Aneke-Nash, Xiaonan Xue, Qibin Qi, Mary L Biggs, Anne Cappola, Lewis Kuller, Michael Pollak, Bruce M Psaty, David Siscovick, Kenneth Mukamal, Howard D Strickler, Robert C Kaplan
Context: Insulin like growth factor-I (IGF-I) has structural/functional similarities with insulin and may play a role in glucose homeostasis, along with IGF binding protein-3 (IGFBP-3), which binds the majority of circulating IGF-I. Objective: To assess whether IGF-I and IGFBP-3 are associated with higher risk of incident diabetes in older adults. Design: Participants in the Cardiovascular Health Study (n=3133), a cohort of adults aged ≥65 years, were observed for 16 years (n=3133) for the development of incident diabetes...
October 12, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29037885/national-trends-and-outcomes-of-cardiac-arrest-in-opioid-overdose
#2
Ankit Sakhuja, Matthew Sztajnkrycer, Saraschandra Vallabhajosyula, Wisit Cheungpasitporn, Richard Patch, Jacob Jentzer
AIM: To investigate the epidemiology and outcomes of cardiac arrests associated with opioid overdoses. Recent data suggest that drug overdoses are responsible for more deaths than motor vehicle crashes or firearms in the United States each year, with opioids being involved in majority of drug overdose deaths. Despite the potential for opioids to cause cardiac arrest, few studies have examined this association. PATIENTS AND METHODS: Using data from National (Nationwide) Inpatient Sample database from years 2000-2013, we identified hospitalizations with drug overdoses using ICD-9-CM codes...
October 13, 2017: Resuscitation
https://www.readbyqxmd.com/read/29034782/the-comparative-epidemiology-of-pediatric-severe-sepsis
#3
Mary E Hartman, Mohammed J Saeed, Kimberly N Powell, Margaret A Olsen
OBJECTIVE: To determine whether the coding strategies used to identify severe sepsis in administrative data sets could identify cases with comparable case mix, hospitalization characteristics, and outcomes as a cohort of children diagnosed with severe sepsis using strict clinical criteria. METHODS: We performed a retrospective cohort study using data from 2005 to 2011 from the New York and Florida State Inpatient Databases, available from the US Healthcare Cost and Utilization Project...
January 1, 2017: Journal of Intensive Care Medicine
https://www.readbyqxmd.com/read/29030143/impact-of-atrial-fibrillation-on-outcomes-with-motor-vehicle-accidents
#4
Kanishk Agnihotri, N V Pothineni, Paris Charilaou, Vaibhav R Vaidya, Badal Thakkar, Vishal Goyal, Sabeeda Kadavath, Nileshkumar Patel, Apurva Badheka, Peter Noseworthy, Suraj Kapa, Paul Friedman, Bernard Gersh, Hakan Paydak, Abhishek Deshmukh
BACKGROUND: We examined the effect of AF a commonly encountered arrhythmia with significant morbidity on mortality following a motor vehicle accident (MVA) related hospitalization. METHODS: The Nationwide Inpatient Sample (NIS) was queried to identify patients with AF (ICD-9 CM 427.31) and MVA (ICD-9 CM E810.0-E819.9), considered separately and together, from 2003 through 2012. Baseline characteristics were identified and multilevel mixed model multivariate analysis was employed to verify the impact of AF on in-patient mortality in survivors...
October 3, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/29029289/post-traumatic-hydrocephalus-in-children-a-retrospective-study-in-42-pediatric-hospitals-using-the-pediatric-health-information-system
#5
Robert H Bonow, Assaf P Oron, Brian W Hanak, Samuel R Browd, Randall M Chesnut, Richard G Ellenbogen, Monica S Vavilala, Frederick P Rivara
BACKGROUND: Post-traumatic hydrocephalus (PTH) is a potentially treatable cause of poor recovery from traumatic brain injury (TBI) that remains poorly understood, particularly among children. OBJECTIVE: To better understand the risk factors for pediatric PTH using a large, multi-institutional database. METHODS: We conducted a retrospective cohort study using administrative data from 42 pediatric hospitals participating in the Pediatric Health Information System...
October 6, 2017: Neurosurgery
https://www.readbyqxmd.com/read/29027297/factors-associated-with-ambulatory-care-sensitive-emergency-department-visits-for-south-carolina-medicaid-members-with-intellectual-disability
#6
S McDermott, J Royer, J R Mann, B S Armour
INTRODUCTION: Ambulatory care sensitive conditions (ACSCs) can be seen as failure of access or management in primary care settings. Identifying factors associated with ACSCs for individuals with an Intellectual Disability (ID) provide insight into potential interventions. METHOD: To assess the association between emergency department (ED) ACSC visits and a number of demographic and health characteristics of South Carolina Medicaid members with ID. A retrospective cohort of adults with ID was followed from 2001 to 2011...
October 13, 2017: Journal of Intellectual Disability Research: JIDR
https://www.readbyqxmd.com/read/29027208/occurrence-of-acute-renal-failure-on-the-same-day-as-immune-globulin-product-administrations-during-2008-to-2014
#7
Bola F Ekezue, Gayathri Sridhar, Richard A Forshee, Hector S Izurieta, Nandini Selvam, Paul D Mintz, Steven A Anderson, Mikhail D Menis
BACKGROUND: Acute renal failure (ARF) is a rare serious adverse event after immune globulin (IG) use. Our large claims-based study evaluated occurrence of same-day ARF after administration of different IGs and ascertained potential risk factors, during the 2008 to 2014 study period. STUDY DESIGN AND METHODS: A retrospective cohort study was conducted using a large commercial administrative database. The cohort included individuals exposed to IG products as identified by procedure codes...
October 12, 2017: Transfusion
https://www.readbyqxmd.com/read/29018647/burden-of-arrhythmias-in-epilepsy-patients-a-nationwide-inpatient-analysis-of-1-4-million-hospitalizations-in-the-united-states
#8
Rupak Desai, Chintan Rupareliya, Upenkumar Patel, Syeda Naqvi, Smit Patel, Abhishek Lunagariya, Zabeen Mahuwala
Arrhythmias have been one of the common complications in epilepsy patients and have also been the reason for death. However, limited data exist about the burden and outcomes of arrhythmias by subtypes in epilepsy. Our study aims at evaluating the burden and differences in outcomes of various subtypes of arrhythmias in epilepsy patient population. The Nationwide Inpatient Sample (NIS) database from 2014 was examined for epilepsy and arrhythmias related discharges using appropriate International Classification of Disease, Ninth Revision Clinical Modification (ICD-9-CM) codes...
August 8, 2017: Curēus
https://www.readbyqxmd.com/read/29017514/impact-of-type-2-diabetes-mellitus-on-in-hospital-mortality-after-major-cardiovascular-events-in-spain-2002-2014
#9
José M de Miguel-Yanes, Rodrigo Jiménez-García, Valentín Hernández-Barrera, Manuel Méndez-Bailón, Javier de Miguel-Díez, Ana Lopez-de-Andrés
BACKGROUND: Diabetes mellitus has long been associated with cardiovascular events. Nevertheless, the higher burden of traditional cardiovascular risk factors reported in high-income countries is offset by a more widespread use of preventive measures and revascularization or other invasive procedures. The aim of this investigation is to describe trends in number of cases and outcomes, in-hospital mortality (IHM) and length of hospital stay (LHS), of hospital admissions for major cardiovascular events between type 2 diabetes (T2DM) and matched non-diabetes patients...
October 10, 2017: Cardiovascular Diabetology
https://www.readbyqxmd.com/read/29016436/trends-and-disparities-in-cervical-spine-fusion-procedures-utilization-in-the-new-york-state
#10
Rui Feng, Mark Finkelstein, Khawaja Bilal, Eric K Oermann, Michael Palese, John Caridi
STUDY DESIGN: A retrospective review of the Statewide Planning and Research Cooperative System database of the New York State. OBJECTIVE: This study examined the rate of increase of cervical spine fusion procedures at low-, medium-, and high-volume hospitals, and analyzed racial and socioeconomic characteristics of the patient population treated at these three volume categories. SUMMARY OF BACKGROUND DATA: There has been a steady increase in spinal fusion procedures performed each year in the US, especially cervical and lumbar fusion...
October 9, 2017: Spine
https://www.readbyqxmd.com/read/28985839/peritoneal-drainage-is-associated-with-higher-survival-rates-for-necrotizing-enterocolitis-in-premature-extremely-low-birth-weight-infants
#11
Jun Tashiro, Amy E Wagenaar, Eduardo A Perez, Juan E Sola
BACKGROUND: To evaluate peritoneal drainage (PD) and laparotomy ± resection/ostomy (LAP) as initial approaches to the surgical management of necrotizing enterocolitis (NEC) in premature, extremely low birth weight (ELBW) infants. METHODS: Kids' Inpatient Database (2003-2012) was searched for cases of NEC (International Classification of Diseases, ninth revision, Clinical Modification [ICD-9-CM] 777.5x) in premature (<37 weeks), extremely low birth weight (<1000 g) infants...
October 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28981480/retention-in-medical-care-among-insured-children-with-diagnosed-hiv-infection-united-states-2010-2014
#12
Mary R Tanner, Tim Bush, Steven R Nesheim, Paul J Weidle, Kathy K Byrd
In 2014, an estimated 2,477 children aged <13 years were living with diagnosed human immunodeficiency virus (HIV) infection in the United States (1). Nationally, little is known about how well children with a diagnosis of HIV infection are retained in medical care. CDC analyzed insurance claims data to evaluate retention in medical care for children in the United States with a diagnosis of HIV infection. Data sources were the 2010-2014 MarketScan Multi-State Medicaid and MarketScan Commercial Claims and Encounters databases...
October 6, 2017: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/28972929/risks-of-road-injuries-in-patients-with-bipolar-disorder-and-associations-with-drug-treatments-a-population-based-matched-cohort-study
#13
Vincent Chin-Hung Chen, Yao-Hsu Yang, Chuan-Pin Lee, Jennifer Wong, Lynn Ponton, Yena Lee, Roger S McIntyre, Kuo-You Huang, Shu-I Wu
OBJECTIVE: Using a nation-wide, population-based dataset, we aimed to investigate the risk of road injury among individuals with bipolar disorder (BD) compared to individuals without BD. In addition, we investigated the putative moderating effects of prescription for lithium, anticonvulsants, antidepressants, and/or first- or second-generation antipsychotic agents on the association between BD and risk of road injury. METHOD: As part of an16-year longitudinal cohort study, we compared the risk of road injuries among study subjects aged 16 and above with a diagnosis of BD, with ten age- and sex-matched sample of individuals without BD...
September 23, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28972923/medicaid-insurance-as-primary-payer-predicts-increased-mortality-after-total-hip-replacement-in-the-state-inpatient-databases-of-california-florida-and-new-york
#14
Hannah F Xu, Robert S White, Dahniel L Sastow, Michael H Andreae, Licia K Gaber-Baylis, Zachary A Turnbull
STUDY OBJECTIVE: To confirm the relationship between primary payer status as a predictor of increased perioperative risks and post-operative outcomes after total hip replacements. DESIGN: Retrospective cohort study. SETTING: Administrative database study using 2007-2011 data from California, Florida, and New York from the State Inpatient Databases (SID), Healthcare Cost and Utilization Project, Agency for Healthcare Research and Quality. PATIENTS: 295,572 patients age≥18years old who underwent total hip replacement with non-missing insurance data were collected, using International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) diagnoses and procedures code (ICD-9-CM code 81...
September 30, 2017: Journal of Clinical Anesthesia
https://www.readbyqxmd.com/read/28960732/estimated-rates-of-influenza-associated-outpatient-visits-during-2001-2010-in-six-us-integrated-health-care-delivery-organizations
#15
Hong Zhou, William W Thompson, Edward A Belongia, Ashley Fowlkes, Roger Baxter, Steven J Jacobsen, Michael L Jackson, Jason M Glanz, Allison L Naleway, Derek C Ford, Eric Weintraub, David K Shay
BACKGROUND: Population-based estimates of influenza-associated outpatient visits including both pandemic and inter-pandemic seasons are uncommon. Comparisons of such estimates with laboratory-confirmed rates of outpatient influenza are rare. OBJECTIVE: To estimate influenza-associated outpatient visits in six US integrated health care delivery organizations enrolling ~7.7 million persons. METHODS: Using negative-binomial regression methods, we modeled rates of influenza-associated visits with ICD-9-CM-coded pneumonia or acute respiratory outpatient visits during 2001-10...
September 27, 2017: Influenza and Other Respiratory Viruses
https://www.readbyqxmd.com/read/28951646/inpatient-orthopaedic-hardware-removal-in-children-a-cross-sectional-study
#16
Alexandre Boulos, Steven F DeFroda, Justin E Kleiner, Nathan Thomas, Joseph A Gil, Aristides I Cruz
INTRODUCTION: Few data describe the specific reasons for inpatient hardware removal in the pediatric population. This study was designed to understand the conditions necessitating inpatient removal following fracture surgery. Cost data was analyzed to understand the financial implications of these procedures. METHODS: The Kids' Inpatient Database (KID) was evaluated for the year 2012. Patients undergoing open reduction internal fixation following upper and lower extremity fractures as well as those undergoing hardware removal due to hardware complications were identified using ICD-9 CM diagnosis and procedure codes...
July 2017: Journal of Clinical Orthopaedics and Trauma
https://www.readbyqxmd.com/read/28951086/trends-in-pneumococcal-meningitis-hospitalizations-following-the-introduction-of-the-13-valent-pneumococcal-conjugate-vaccine-in-the-united-states
#17
David M Jacobs, Francine Yung, Emily Hart, Melanie N H Nguyen, Amy Shaver
BACKGROUND: The 13-valent pneumococcal conjugate vaccine (PCV13) was introduced in 2010 in the U.S. and its impact on pneumococcal meningitis (PM) is unknown. We assessed the impact of PCV13 on PM hospitalization rates 4years after the vaccine was introduced. METHODS: This was a retrospective analysis of the National Inpatient Sample from 2008-2014. Patients with an ICD-9-CM code for PM (320.1) were identified and rates calculated using US Census data as the denominator...
October 27, 2017: Vaccine
https://www.readbyqxmd.com/read/28949045/the-impact-of-diabetes-mellitus-and-hepatitis-b-virus-co-infection-on-patients-with-chronic-hepatitis-c-a-territory-wide-cohort-study
#18
Shreenidhi Subramaniam, Vincent Wai-Sun Wong, Yee-Kit Tse, Terry Cheuk-Fung Yip, Henry Lik-Yuen Chan, Grace Lai-Hung Wong
BACKGROUND & AIM: Studies have demonstrated a higher prevalence of diabetes mellitus (DM) in patients with chronic hepatitis C (CHC). Furthermore, co-infection with hepatitis B virus (HBV) is common due to its endemicity in Asian-Pacific regions. We aimed to investigate the impact of DM and HBV co-infection on the clinical outcomes in Chinese CHC patients. METHODS: We conducted a territory-wide cohort study using the database from Hospital Authority, the sole public medical service provider in Hong Kong...
September 26, 2017: Journal of Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28945179/syndromic-surveillance-of-mental-and-substance-use-disorders-a-validation-study-using-emergency-department-chief-complaints
#19
Sidra Goldman-Mellor, Yusheng Jia, Kevin Kwan, Jared Rutledge
OBJECTIVE: This study evaluated whether emergency department (ED) patient presentations for problems related to mental and substance use disorders could be validly monitored by a syndromic surveillance system that uses chief complaints to identify mental disorders. METHODS: The study used syndromic surveillance data on 146,315 ED visits to participating Fresno County, California, hospitals between January 1 and December 31, 2013. Free-text patient chief complaints are automatically classified into syndromes based on the developer's algorithms...
September 15, 2017: Psychiatric Services: a Journal of the American Psychiatric Association
https://www.readbyqxmd.com/read/28937935/the-impact-of-the-2006-massachusetts-health-care-reform-law-on-spine-surgery-patient-payer-mix-status-and-age
#20
Nicolas W Villelli, Hong Yan, Jian Zou, Nicholas M Barbaro
OBJECTIVE Several similarities exist between the Massachusetts health care reform law of 2006 and the Affordable Care Act (ACA). The authors' prior neurosurgical research showed a decrease in uninsured surgeries without a significant change in surgical volume after the Massachusetts reform. An analysis of the payer-mix status and the age of spine surgery patients, before and after the policy, should provide insight into the future impact of the ACA on spine surgery in the US. METHODS Using the Massachusetts State Inpatient Database and spine ICD-9-CM procedure codes, the authors obtained demographic information on patients undergoing spine surgery between 2001 and 2012...
September 15, 2017: Journal of Neurosurgery. Spine
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