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https://www.readbyqxmd.com/read/28339357/development-of-a-score-for-assessment-of-radiologic-damage-in-large-vessel-vasculitis-combined-arteritis-damage-score-cards
#1
Daiki Nakagomi, Claire Cousins, Jan Sznajd, Shunsuke Furuta, Aladdin J Mohammad, Raashid Luqmani, David Jayne
OBJECTIVES: Outcome assessment in large-vessel vasculitis (LVV) remains challenging and this impairs patient management and the conduct of clinical studies. Previous proposals for outcome tools have not included imaging. This study aimed to develop an imaging score to quantify damage in LVV and to assess the difference between Takayasu (TAK) and giant cell arteritis (GCA). METHODS: Ninety-six patients (41 TAK, 55 GCA) were identified from local registries at two University Hospitals in the UK...
March 13, 2017: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/28329327/association-of-accelerometer-measured-physical-activity-with-leukocyte-telomere-length-among-older-women
#2
Aladdin H Shadyab, Michael J LaMonte, Charles Kooperberg, Alexander P Reiner, Cara L Carty, Todd M Manini, Lifang Hou, Chongzhi Di, Andrea Z LaCroix
Background: Previous studies on physical activity and telomere length have relied largely upon self-reported physical activity data, and few studies have examined older adults. The association of objectively measured physical activity with leukocyte telomere length (LTL) is currently unknown. Methods: In this study, we examined cross-sectional associations between accelerometer-measured total, light, and moderate-to-vigorous physical activity (MVPA) and LTL, measured using Southern blot...
March 9, 2017: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://www.readbyqxmd.com/read/28324783/recent-updates-of-carbapenem-antibiotics
#3
REVIEW
Mohammed I El-Gamal, Imen Brahim, Noorhan Hisham, Rand Aladdin, Haneen Mohammed, Amany Bahaaeldin
Carbapenems are among the most commonly used and the most efficient antibiotics since they are relatively resistant to hydrolysis by most β-lactamases, they target penicillin-binding proteins, and generally have broad-spectrum antibacterial effect. In this review, we described the initial discovery and development of carbapenems, chemical characteristics, in vitro/in vivo activities, resistance studies, and clinical investigations for traditional carbapenem antibiotics in the market; imipenem-cilastatin, meropenem, ertapenem, doripenem, biapenem, panipenem/betamipron in addition to newer carbapenems such as razupenem, tebipenem, tomopenem, and sanfetrinem...
March 16, 2017: European Journal of Medicinal Chemistry
https://www.readbyqxmd.com/read/28237984/effect-of-a-quality-improvement-program-to-improve-guideline-adherence-and-attainment-of-clinical-standards-in-dialysis-care-report-of-outcomes-in-year-1
#4
Sajeda Youssouf, Azri Nache, Chandrakumaran Wijesekara, Rachel J Middleton, David Lewis, Aladdin E Shurrab, Edmond O'Riordan, Lesley P Lappin, Donal O'Donoghue, Philip A Kalra, Janet Hegarty
BACKGROUND: Best practice in dialysis is synthesised in clear international guidelines. However, a large gap remains between the international guidelines and the actual delivery of care. In this paper, we report outcomes for the first year of a multifaceted dialysis improvement programme in our network. METHODS: One year collaborative involving 3 haemodialysis units and a peritoneal dialysis (PD) programme involving 299 dialysis patients. Each unit addressed a different indicator (unit A - catheter-related bloodstream infection [CRBSI], unit B - pre-dialysis blood pressure [BP], unit C - dialysis dose, unit D - anaemia) with a shared aim to match the top 10% in the UK...
February 25, 2017: Nephron
https://www.readbyqxmd.com/read/28134644/management-of-rhinophyma-outcomes-study-of-the-subunit-method
#5
Aladdin H Hassanein, Raj M Vyas, Jessica Erdmann-Sager, Edward J Caterson, Julian J Pribaz
BACKGROUND: Rhinophyma causes a nasal deformity and functional airway obstruction. Partial excision (eg, tangential) with secondary healing commonly removes hypertrophic soft tissues but does not improve nasal support. The subunit method for rhinophyma uses 6 nasal flaps to provide exposure for removal of rhinophymatous tissue and enhance structure. The purpose of this study was to evaluate outcomes of subunit method. METHODS: Medical records of patients with rhinophyma treated with the subunit method between 2013 and 2016 were analyzed...
January 27, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28130351/repeatability-and-agreement-of-ocular-biometry-measurements-aladdin-versus-lenstar
#6
Colm McAlinden, Rongrong Gao, Ayong Yu, Xiaorui Wang, Jing Yang, Ye Yu, Hao Chen, Qinmei Wang, Jinhai Huang
OBJECTIVE: To assess the repeatability and agreement between the Aladdin and Lenstar biometers. METHODS: Three consecutive measurements of the right eye of 102 subjects were acquired by the Aladdin (V.1.1.3) and the Lenstar (V.1.0.3), respectively, with a random order of which biometer to use first. Parameters compared included axial length (AL), anterior chamber depth (ACD), flat keratometry (Kf), steep keratometry (Ks), mean keratometry (Km), J0, J45 and white-to-white (WTW) distance...
January 27, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28100466/associations-of-accelerometer-measured-and-self-reported-sedentary-time-with-leukocyte-telomere-length-in-older-women
#7
Aladdin H Shadyab, Caroline A Macera, Richard A Shaffer, Sonia Jain, Linda C Gallo, Michael J LaMonte, Alexander P Reiner, Charles Kooperberg, Cara L Carty, Chongzhi Di, Todd M Manini, Lifang Hou, Andrea Z LaCroix
Few studies have assessed the association of sedentary time with leukocyte telomere length (LTL). In a cross-sectional study conducted in 2012-2013, we examined associations of accelerometer-measured and self-reported sedentary time with LTL in a sample of 1,481 older white and African-American women from the Women's Health Initiative and determined whether associations varied by level of moderate- to vigorous-intensity physical activity (MVPA). The association between sedentary time and LTL was evaluated using multiple linear regression models...
February 1, 2017: American Journal of Epidemiology
https://www.readbyqxmd.com/read/28050321/comparison-of-anterior-segment-measurements-obtained-by-aladdin-optical-biometer-and-sirius-corneal-topography
#8
Onur Polat, Zeki Baysal, Serkan Özcan, Sibel İnan, Ümit Übeyt İnan
OBJECTIVES: To assess the agreement of anterior segment parameter measurements derived from Aladdin optical biometer using optical low coherence interferometer and Sirius corneal topography using combined Scheimpflug-Placido disk. MATERIALS AND METHODS: Data obtained using the Aladdin and Sirius systems from 110 eyes of 59 subjects who had no health problems other than refractive errors were retrospectively evaluated. Anterior chamber depth (ACD), flat (K1) and steep (K2) keratometry readings, and white-to-white distance (WTW) measurements taken with both devices were noted...
December 2016: Turkish Journal of Ophthalmology
https://www.readbyqxmd.com/read/27889244/medicinal-uses-chemistry-and-pharmacology-of-dillenia-species-dilleniaceae
#9
REVIEW
Carla W Sabandar, Juriyati Jalil, Norizan Ahmat, Nor-Ashila Aladdin
The genus Dillenia is comprised of about 100 species of evergreen and deciduous trees or shrubs of disjunct distribution in the seasonal tropics of Madagascar through South and South East Asia, Malaysia, North Australia, and Fiji. Species from this genus have been widely used in medicinal folklore to treat cancers, wounds, jaundice, fever, cough, diabetes mellitus, and diarrhea as well as hair tonics. The plants of the genus also produce edible fruits and are cultivated as ornamental plants. Flavonoids, triterpenoids, and miscellaneous compounds have been identified in the genus...
February 2017: Phytochemistry
https://www.readbyqxmd.com/read/27854529/maternal-age-at-childbirth-and-parity-as-predictors-of-longevity-among-women-in-the-united-states-the-women-s-health-initiative
#10
Aladdin H Shadyab, Margery L S Gass, Marcia L Stefanick, Molly E Waring, Caroline A Macera, Linda C Gallo, Richard A Shaffer, Sonia Jain, Andrea Z LaCroix
OBJECTIVES: To examine associations of maternal age at childbirth and parity with survival to age 90 years (longevity). METHODS: We performed a prospective study among a multiethnic cohort of postmenopausal US women in the Women's Health Initiative recruited from 1993 to 1998 and followed through August 29, 2014. We adjusted associations with longevity for demographic, lifestyle, reproductive, and health-related characteristics. RESULTS: Among 20 248 women (mean age at baseline, 74...
January 2017: American Journal of Public Health
https://www.readbyqxmd.com/read/27803140/rate-of-comorbidities-in-giant-cell-arteritis-a-population-based-study
#11
Aladdin J Mohammad, Martin Englund, Carl Turesson, Gunnar Tomasson, Peter A Merkel
OBJECTIVE: To compare the rate of occurrence of comorbidities, including severe infections, in a population-based cohort of patients with biopsy-proven giant cell arteritis (GCA) with a reference population in Southern Sweden. METHODS: The study included a population-based cohort of biopsy-proven GCA cases diagnosed between 1998 and 2010 from the Skåne region in Southern Sweden (population: 1.2 million). For each patient, 4 reference subjects were identified from the general population and matched for age, sex, area of residence, and date of diagnosis of GCA...
January 2017: Journal of Rheumatology
https://www.readbyqxmd.com/read/27777163/comparative-study-of-2-skin-incisions-for-microscopic-lumbar-discectomy
#12
Waeel Hamouda, Mohammed Aladdin, Sarah AlMuammar, Danya Gari
OBJECTIVE: Microscopic lumbar discectomy is a common minimally invasive surgery. A transverse skin incision has sound theoretical cosmetic advantages compared with the classic vertical incision. We compared transverse and vertical skin incisions for microscopic discectomy regarding cosmetic outcome, postoperative pain, and the provided surgical cutaneous inlet. METHODS: This prospective study enrolled 86 patients who were randomly assigned to a vertical incision group or a transverse incision group...
April 2017: World Neurosurgery
https://www.readbyqxmd.com/read/27751912/bariatric-manipulation-of-gastric-arteries-a-systematic-review-on-the%C3%A2-potential-concept-for-treatment-of-obesity
#13
REVIEW
Saeed Shoar, Alan A Saber, Mohammaed Aladdin, Moataz M Bashah, Mohammed J AlKuwari, Mohamed Rizwan, Raul J Rosenthal
BACKGROUND: Gastric artery embolization (GAE) has recently received attention as a minimally invasive intervention in bariatric setting. AIMS: The current systematic review aimed to gather and categorizes the existing data in the literature regarding bariatric gastric artery manipulation. This will highlight the importance of this potential concept as a therapeutic modality. METHODS: A PubMed/Medline search was conducted to identify animal and human studies investigating the effect of gastric artery manipulation on weight, ghrelin, obesity, and tissue adiposity...
December 2016: International Journal of Surgery
https://www.readbyqxmd.com/read/27741085/predictability-of-biometry-in-patients-undergoing-cataract-surgery
#14
Nir Sorkin, Amir Rosenblatt, Irina S Barequet
PURPOSE: To compare measurements of axial length (AL), anterior chamber depth (ACD), keratometry (K), and the refractive predictability of the Aladdin and IOLMaster biometry devices in cataract surgery patients. METHODS: A retrospective observational study of eyes undergoing cataract surgery. Data were retrieved on AL, ACD, and K measurements obtained by the Aladdin and the IOLMaster. Furthermore, the postoperative refractive prediction errors were compared between the devices...
December 2016: Optometry and Vision Science: Official Publication of the American Academy of Optometry
https://www.readbyqxmd.com/read/27719662/the-importance-of-military-conscripts-for-surveillance-of-human-immunodeficiency-virus-infection-and-risk-behavior-in-thailand
#15
Aladdin Shadyab, Kenrad E Nelson, Ram Rangsin
The human immunodeficiency virus (HIV) epidemic in Thailand was first recognized in 1988 among injection drug users (IDUs) in Bangkok. Soon thereafter, HIV infections were reported among female sex workers (FSWs) and men attending sexually transmitted disease (STD) clinics. Routine serological surveillance for HIV began in 1991 among young men who were conscripted annually into the Royal Thai Army (RTA). The data from these populations provided a national population-based sample to determine sexual behaviors and HIV prevalence among sexually active young men...
October 6, 2016: Current HIV Research
https://www.readbyqxmd.com/read/27707806/replication-of-genome-wide-association-study-findings-of-longevity-in-white-african-american-and-hispanic-women-the-women-s-health-initiative
#16
Aladdin H Shadyab, Charles Kooperberg, Alexander P Reiner, Sonia Jain, JoAnn E Manson, Chancellor Hohensee, Caroline A Macera, Richard A Shaffer, Linda C Gallo, Andrea Z LaCroix
BACKGROUND: No study has evaluated whether genetic factors are associated with longevity in African Americans or Hispanics, and it is unclear whether genetic factors are associated with healthy aging. METHODS: In this prospective study, we determined whether 14 genetic variants previously associated with longevity in genome-wide association studies were associated with survival to ages 85 and 90 in 11,053 postmenopausal white, African American, and Hispanic women from the Women's Health Initiative...
October 5, 2016: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://www.readbyqxmd.com/read/27664702/axial-length-measurement-failure-rates-with-biometers-using-swept-source-optical-coherence-tomography-compared-to-partial-coherence-interferometry-and-optical-low-coherence-interferometry
#17
Colm McAlinden, Qinmei Wang, Rongrong Gao, Weiqi Zhao, Ayong Yu, Yu Li, Yan Guo, Jinhai Huang
PURPOSE: To compare a new swept-source optical coherence tomography (SSOCT)-based biometer (OA-2000) with the IOLMaster v5.4 (partial-coherence interferometry) and Aladdin (optical low-coherence interferometry) biometers in terms of axial length measurement and failure rate in eyes with cataract. DESIGN: Reliability study. METHODS: A total of 377 eyes of 210 patients were scanned with the 3 biometers in a random order. For each biometer, the number of unobtainable axial length measurements was recorded and grouped as per the type and severity of cataract based on the Lens Opacities Classification System III by the same experienced ophthalmologist...
January 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/27570240/bevacizumab-and-interferon-reduce-venous-recanalization-following-sclerotherapy
#18
Ann M Kulungowski, Aladdin H Hassanein, Carolyn C Foster, Arin K Greene, Steven J Fishman
PURPOSE: The treatment of venous malformations is difficult because these lesions frequently recur after resection or sclerotherapy. The purpose of this study was to determine whether recanalization of sclerosed venous lumens could be prevented with systemic angiogenic inhibition using bevacizumab or peginterferon alfa-2a. METHODS: To establish an animal model of recanalization of sclerosed facial veins, 18 rabbits had ethanol sclerotherapy of 1 facial vein followed by venography after 4weeks (n=6), 12weeks (n=6), and 24weeks (n=6)...
October 2016: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/27558589/the-effect-of-clinical-features-and-glucocorticoids-on-biopsy-findings-in-giant-cell-arteritis
#19
Karin Jakobsson, Lennart Jacobsson, Aladdin J Mohammad, Jan-Åke Nilsson, Kenneth Warrington, Eric L Matteson, Carl Turesson
BACKGROUND: To investigate the effect of baseline clinical characteristics and glucocorticoid treatment on temporal artery biopsy (TAB) findings in patients with giant cell arteritis (GCA). METHODS: Individuals who developed GCA after inclusion in two population-based health surveys were identified through linkage to the local and the national patient registers. In addition, other patients diagnosed with GCA at the Departments of Internal Medicine and Rheumatology at an area hospital were included...
2016: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/27554820/allergy-related-disease-in-relation-to-early-life-exposures-the-aladdin-birth-cohort
#20
Helena Marell Hesla, Fredrik Stenius, Hans Järnbert-Pettersson, Johan Alm
No abstract text is available yet for this article.
August 20, 2016: Journal of Allergy and Clinical Immunology
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