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https://www.readbyqxmd.com/read/29282203/a-low-fat-dietary-pattern-and-diabetes-a-secondary-analysis-from-the-women-s-health-initiative-dietary-modification-trial
#1
Barbara V Howard, Aaron K Aragaki, Lesley F Tinker, Matthew Allison, Melanie D Hingle, Karen C Johnson, JoAnn E Manson, Aladdin H Shadyab, James M Shikany, Linda G Snetselaar, Cynthia A Thomson, Oleg Zaslavsky, Ross L Prentice
OBJECTIVE: We performed a secondary analysis to evaluate the effect of the Women's Health Initiative dietary intervention on incident diabetes and diabetes treatment in postmenopausal women. RESEARCH DESIGN AND METHODS: A total of 48,835 women were randomized to a comparison group or an intervention group that underwent a behavioral/nutritional modification program to decrease fat and increase vegetable, fruit, and grain intake for an average of 8.1 years. Ninety-three percent of participants completed the intervention, and 71% participated in active follow-up through 30 September 2015 (median 17...
December 27, 2017: Diabetes Care
https://www.readbyqxmd.com/read/29237273/a-novel-mechanism-for-atherosclerotic-calcification-potential-resolution-of-the-oxidation-paradox
#2
Aladdin Riad, Chandrakala Aluganti Narasimhulu, Pragney Deme, Sampath Parthasarathy
AIM: In this study, we tested the hypothesis that lipid peroxide-derived dicarboxylic acids, by virtue of their ability bind to calcium, might be involved in atherosclerotic calcification. We determined the ability of azelaic acid (AzA) to promote calcification in human aortic smooth muscle cells (HASMC), identified AzA in human calcified atherosclerotic lesions, and compared its levels with control and non-calcified atherosclerotic lesions. RESULTS: HASMCs efficiently converted 9-oxononanoic acid (ONA), a lipid peroxide derived monocarboxylic aldehyde, to AzA...
December 14, 2017: Antioxidants & Redox Signaling
https://www.readbyqxmd.com/read/29181041/video-assisted-thoracic-surgery-in-hemothorax-evacuation-after-cardiac-surgery-or-cardiac-interventions
#3
Aladdin Bashir, Omar Daraghma, Zbigniew Brzeziński, Dawid Imiełowski, Piotr Daszkiewicz, Witold Gwoźdź, Jerzy Stupała, Paweł Tomaszewski, Jacek Kaperczak
Introduction: Cardiac surgery and cardiac interventions are associated with the risk of iatrogenic complications, including hemothorax. Minimally invasive methods of evacuating hemothorax include video-assisted thoracic surgery (VATS). Aim: This paper presents this method and provides its detailed analysis. Material and methods: The VATS procedures were used to evacuate hemothorax in 8 patients (7 after cardiac surgery and 1 after a cardiac intervention)...
September 2017: Kardiochirurgia i Torakochirurgia Polska, Polish Journal of Cardio-Thoracic Surgery
https://www.readbyqxmd.com/read/29181040/is-there-a-determining-factor-that-predicts-mortality-in-patients-with-congenital-diaphragmatic-hernia
#4
Tansel Gunendi, Basak Erginel, Ercan Bastu, Ibrahim Kalelioglu, Recep Has, Feryal Gun Soysal, Erbug Keskin, Aladdin Celik, Tansu Salman
Aim: This study was designed to investigate the factors affecting the prognosis in neonates with congenital diaphragmatic hernia (CDH) who were treated in our clinic. These factors included prenatal lung-head ratio (LHR), prenatal stomach and liver presence in the thorax, blood gases in the first 24 h and the modified ventilation index (MVI). Material and methods: The study was carried out retrospectively in 30 neonates with prenatally diagnosed left CDH who were treated in our clinic between January 2007 and 2013...
September 2017: Kardiochirurgia i Torakochirurgia Polska, Polish Journal of Cardio-Thoracic Surgery
https://www.readbyqxmd.com/read/29153749/esthetic-abutment-design-for-angulated-screw-channels-a-technical-report
#5
Satoshi Sakamoto, Munehiko Ro, Aladdin Al Ardah, Charles Goodacre
Angulated screw channel system abutments (ASCs) have recently been introduced to address the problem with visible screw access that may compromise esthetics. ASCs allow the screw access to be modified up to 25 degrees relative to the implant axis. However, a widened channel, which may cause thinning of the facial ceramic, is needed at the implant screw head to allow for proper engagement of the screwdriver. This technical report introduces a custom titanium insert design, the Satoshi Sakamoto (SS) abutment...
November 15, 2017: Journal of Prosthetic Dentistry
https://www.readbyqxmd.com/read/29150131/a-3d-printed-guide-for-lateral-approach-sinus-grafting-a-dental-technique
#6
Brian J Goodacre, Rajesh S Swamidass, Jaime Lozada, Aladdin Al-Ardah, Erik Sahl
Lateral approach sinus grafting has become a routine and predictable surgical method of augmenting the pneumatized sinus for implant placement. Outlining the lateral window access can be a challenging task for the clinician to envision and execute. Improper extension and access to the maxillary sinus can prevent proper placement of graft materials and lead to complications. The purpose of this report was to demonstrate a technique that will allow the precise planning of the lateral approach using radiographic information and 3-dimensional (3D) software to 3D-print a surgical guide...
November 15, 2017: Journal of Prosthetic Dentistry
https://www.readbyqxmd.com/read/29142418/marantodes-pumilum-blume-kuntze-inhibited-secretion-of-lipopolysaccharide-and-monosodium-urate-crystal-stimulated-cytokines-and-plasma-prostaglandin-e2
#7
Eldiza Puji Rahmi, Jamia Azdina Jamal, Endang Kumolosasi, Juriyati Jalil, Nor-Ashila Aladdin
Background: Marantodes pumilum is traditionally used for dysentery, gonorrhea, and sickness in the bones. Previous studies revealed its antibacterial and xanthine oxidase inhibitory activities. Objective: To evaluate the inhibitory effects of three M. pumilum varieties on the secretion of lipopolysaccharide (LPS)- and monosodium urate crystal (MSU)-induced cytokines and plasma prostaglandin E2 (PGE2) in vitro. Materials and Methods: The leaves and roots of M...
October 2017: Pharmacognosy Magazine
https://www.readbyqxmd.com/read/29131706/alzheimer-s-disease-current-status-and-future-directions
#8
Deepshikha Bhardwaj, Connie Mitra, Chandrakala Aluganti Narasimhulu, Aladdin Riad, Mitsushita Doomra, Sampath Parthasarathy
Alzheimer's disease (AD) is an age-related neurodegenerative disorder of the brain. The presence of amyloid-beta (Aβ) plaques, neurofibrillary tangles (NFTs), loss of neurons, synapses, and altered sensory perceptions, including memory loss, delineate AD. However, the cause of AD is not clearly known. Several genetic and nongenetic factors have been implicated in the disease. Of the genes, the ɛ4 allele of apolipoprotein E is the largest known genetic risk factor of AD. This review article focuses on the various genetic and other predisposing factors that account for AD, pathophysiology of the disease, and the mechanisms by which Aβ plaques and NFTs are formed and could affect AD brain...
December 2017: Journal of Medicinal Food
https://www.readbyqxmd.com/read/29090488/validation-of-keratometric-measurements-obtained-with-an-intraoperative-image-guided-system-intra-session-repeatability-and-interchangeability-with-an-optical-biometer
#9
Clara Ruiz-Belda, Fermín Rodrigo, David P Piñero
PURPOSE: To evaluate the intra-session repeatability of keratometric measurements obtained in healthy eyes with the Verion image-guided system (Alcon Laboratories Inc, Fort Worth, Texas, USA) as well as the interchangeability of such measurements with those obtained with an optical biometer (Aladdin, Topcon, Tokyo, Japan). METHODS: A total of 53 eyes of 53 patients (age 31-67 years) were enrolled in the study. All eyes received a comprehensive ophthalmologic examination including an analysis with the Verion image-guided and Aladdin systems...
October 31, 2017: Clinical & Experimental Optometry: Journal of the Australian Optometrical Association
https://www.readbyqxmd.com/read/29072621/synthesis-and-2d-qsar-study-of-active-benzofuran-based-vasodilators
#10
Nagy M Khalifa, Aladdin M Srour, Somaia S Abd El-Karim, Dalia O Saleh, Mohamed A Al-Omar
A new series of 2-alkyloxy-pyridine-3-carbonitrile-benzofuran hybrids (4a-x) was synthesized. All the new derivatives were examined via the standard technique for their vasodilation activity. Some of the investigated compounds exhibited a remarkable activity, with compounds 4w, 4e, 4r, 4s, 4f and 4g believed to be the most active hits in this study with IC50 values 0.223, 0.253, 0.254, 0.268, 0.267 and 0.275 mM, respectively, compared with amiodarone hydrochloride, the reference standard used (IC50 = 0.300 mM)...
October 26, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29064770/managing-titanium-mesh-exposure-with-the-partial-removal-of-the-exposed-site-a-case-series-study
#11
Aladdin Al-Ardah, Abdulaziz AlHelal, Periklis Proussaefs, Bader AlBader, Abdulakareem A Al Humaidan, Jaime Lozada
This case series report aimed at evaluating the efficacy of addressing exposure of the Titanium mesh by sectioning the exposed portion of the mesh and allowing the remaining portion in place while bone maturation is complete. The use of Titanium mesh for localized alveolar ridge augmentation was evaluated with clinical and radiographic analysis. Materials and methods in the current case series report includes four consecutively treated patients where a titanium mesh was utilized as a barrier for localized alveolar ridge augmentation and exposure of the mesh occurred after the alveolar ridge augmentation procedure...
October 24, 2017: Journal of Oral Implantology
https://www.readbyqxmd.com/read/28979276/effects-of-temperature-stresses-on-the-resistance-of-chickpea-genotypes-and-aggressiveness-of-didymella-rabiei-isolates
#12
Seid Ahmed Kemal, Sanae Krimi Bencheqroun, Aladdin Hamwieh, Muhammad Imtiaz
Chickpea (Cicer arietinum L.) is an important food and rotation crop in many parts of the world. Cold (freezing and chilling temperatures) and Ascochyta blight (Didymella rabiei) are the major constraints in chickpea production. The effects of temperature stresses on chickpea susceptibility and pathogen aggressiveness are not well documented in the Cicer-Didymella pathosystem. Two experiments were conducted under controlled conditions using chickpea genotypes and pathogen isolates in 2011 and 2012. In Experiment 1, four isolates of D...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28973844/rituximab-for-the-treatment-of-adult-onset-iga-vasculitis-henoch-sch%C3%A3-nlein-purpura
#13
Federica Maritati, Roberta Fenoglio, Evangeline Pillebout, Giacomo Emmi, Maria L Urban, Rossana Rocco, Maria Nicastro, Monia Incerti, Matteo Goldoni, Giorgio Trivioli, Elena Silvestri, Aladdin J Mohammad, David Jayne, Per Eriksson, Mårten Segelmark, Pavel Novikov, Helen Harris, Dario Roccatello, Augusto Vaglio
OBJECTIVE: Adult-onset IgA vasculitis (IgAV, formerly Henoch-Schönlein purpura) is a rare systemic vasculitis characterised by IgA1-dominant deposits. The treatment of adult-onset IgAV is controversial and is based on the combination of glucocorticoids and immunosuppressive agents, but many patients have refractory or relapsing disease despite treatment. Rituximab is a B cell-depleting antibody of proven efficacy in anti-neutrophil cytoplasmic antibody-associated vasculitis. We tested the efficacy and safety of rituximab in a multicentre cohort of patients with adult-onset IgAV...
October 3, 2017: Arthritis & Rheumatology
https://www.readbyqxmd.com/read/28973836/general-and-abdominal-obesity-as-risk-factors-for-late-life-mobility-limitation-after-total-knee-or-hip-replacement-for-osteoarthritis-among-women
#14
Aladdin H Shadyab, Wenjun Li, Charles B Eaton, Andrea Z LaCroix
OBJECTIVE: To investigate associations of body mass index (BMI), waist circumference (WC), and waist-hip ratio (WHR) with survival to age 85 with mobility limitation or death before age 85 among older women with total knee (TKR) or total hip (THR) replacement for osteoarthritis. METHODS: This was a prospective study of women (aged 65-79 years at baseline) from the Women's Health Initiative recruited during 1993-1998 and followed through 2012. Women's Health Initiative data were linked to Medicare claims data to determine TKR (n=1,867) and THR (n=944) for osteoarthritis...
October 3, 2017: Arthritis Care & Research
https://www.readbyqxmd.com/read/28955485/long-term-patient-survival-in-a-swedish-population-based-cohort-of-patients-with-anca-associated-vasculitis
#15
Caroline Heijl, Aladdin J Mohammad, Kerstin Westman, Peter Höglund
OBJECTIVES: Patients with antineutrophil cytoplasmatic antibodies-associated vasculitides (AAV) exhibit higher mortality than the general population. In the current study, we assessed whether cluster affiliation based on clinical presentation might predict mortality. METHODS: With case record review, the outcomes for a population-based cohort of patients diagnosed with AAV in southern Sweden (catchment area of 0.7 million inhabitants) between 1997 and 2010 were assessed...
2017: RMD Open
https://www.readbyqxmd.com/read/28939832/inherent-humic-substance-promotes-microbial-denitrification-of-landfill-leachate-via-shifting-bacterial-community-improving-enzyme-activity-and-up-regulating-gene
#16
Shanshan Dong, Mu Li, Yinguang Chen
Microbial denitrification is the main pathway for nitrogen removal of landfill leachate. Although humic substances (HSs) have been reported in landfill leachate, the effects of HS on denitrification process of activated sludge for leachate treatment are still unknown. In this study, we adopted SAHA as the model HS to study the effects of HS on the denitrification of landfill leachate. After long-term operation at 10 mg/L of Shanghai Aladdin Humic Acid (SAHA), the final nitrate concentration and nitrite accumulation were much lower than the control (5...
September 22, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28845411/leech-therapy-for-treating-priapism-case-report
#17
Sayed Aladdin Asgari, Sadeq Rostami, Mojtaba Teimoori
Priapism is well-defined by persistent, painful penile erection which happens without sexual stimulation. Currently, the hirudotherapy is practiced to treat venous congestion and subsequent compartment syndrome. Here we will report a case of a male with priapism treated by leeches. The case was a 26 yr old young single male referred to the Razi Hospital Emergency Department, Guilan University of Medical Sciences, Rasht, Iran due to long-time spontaneous erections. The patient had no history of mental disorders, trauma or sickle cell anemia...
July 2017: Iranian Journal of Public Health
https://www.readbyqxmd.com/read/28831342/diagnostic-accuracy-of-lymphoscintigraphy-for-lymphedema-and-analysis-of-false-negative-tests
#18
Aladdin H Hassanein, Reid A Maclellan, Frederick D Grant, Arin K Greene
Lymphedema is the chronic enlargement of tissue due to inadequate lymphatic function. Diagnosis is made by history and physical examination and confirmed with lymphoscintigraphy. The purpose of this study was to assess the accuracy of lymphoscintigraphy for the diagnosis of lymphedema and to determine characteristics of patients with false-negative tests. METHODS: Individuals referred to our lymphedema program with "lymphedema" between 2009 and 2016 were analyzed. Subjects were assessed by history, physical examination, and lymphoscintigraphy...
July 2017: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/28827482/insulin-neuritis-and-effect-of-pregabalin
#19
Yasser Aladdin, Thomas Jeerakathil, Zaeem A Siddiqi
INTRODUCTION: Insulin neuritis (IN) is a rare condition that results in acute painful neuropathy. It occurs classically in patients with diabetes mellitus with uncontrolled sugar levels who are started on insulin therapy leading to a precipitous normalization of blood sugar levels. The condition is heralded by severe and generalized burning pain along with significant weight loss and mood issues. The diagnosis is mainly clinical and the etiology of IN remains obscure. METHODS AND RESULTS: We report on 2 cases who developed acute and excruciating neuropathic pain after institution of insulin therapy for poorly controlled diabetes mellitus...
September 2017: Journal of Clinical Neuromuscular Disease
https://www.readbyqxmd.com/read/28765251/severe-infection-in-antineutrophil-cytoplasmic-antibody-associated-vasculitis
#20
Aladdin J Mohammad, Mårten Segelmark, Rona Smith, Martin Englund, Jan-Åke Nilsson, Kerstin Westman, Peter A Merkel, David R W Jayne
OBJECTIVE: To compare the rate of severe infections after the onset of antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) with the rate in the background population, and to identify predictors of severe infections among patients with AAV. METHODS: The study cohort was 186 patients with AAV diagnosed from 1998 to 2010, consisting of all known cases in a defined population in southern Sweden. For each patient, 4 age-and sex-matched reference subjects were randomly chosen from the background population...
October 2017: Journal of Rheumatology
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