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Female urinary dysfunction

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https://www.readbyqxmd.com/read/29667744/intraurethral-erbium-yag-laser-for-the-management-of-urinary-symptoms-of-genitourinary-syndrome-of-menopause-a-pilot-study
#1
Adrian Gaspar, Sandra Maestri, Joaquin Silva, Hugo Brandi, Daniel Luque, Neža Koron, Zdenko Vižintin
OBJECTIVES: Genitourinary syndrome of menopause (GSM) combines the conditions of vulvovaginal atrophy (VVA) and urinary tract dysfunction, which is a result of urethral atrophy. There are several treatment methods available for the management of vulvovaginal symptoms of GSM, whereas urinary tract dysfunction often remains overlooked and undertreated. The objective of this pilot study was to assess the safety and efficacy of intraurethral Er:YAG laser treatment of urinary symptoms of GSM...
April 18, 2018: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/29661209/gastrointestinal-and-urinary-complaints-in-adults-with-hereditary-spastic-paraparesis
#2
Øivind J Kanavin, Krister W Fjermestad
BACKGROUND: Hereditary spastic paraparesis (HSP) is a group of rare genetic disorders affecting the central nervous system. Pure HSP is limited to lower limb spasticity and urinary voiding dysfunction. Complex HSP involves additional neurological features. Beyond the described core symptoms, knowledge about the burden of disease for adults with HSP is limited, particularly regarding gastrointestinal functions, fecal incontinence, and urinary symptoms. METHODS: We conducted a cross-sectional self-report survey with 108 adult HSP patients (Mage  = 57...
April 16, 2018: Orphanet Journal of Rare Diseases
https://www.readbyqxmd.com/read/29657204/urinary-tract-infection-in-renal-transplant-recipients-at-a-tertiary-care-center-in-india
#3
Debabrata Mukherjee, Sourabh Sharma, Ranjith K Nair, Bhaskar Datt, Dhawal Arora, Ananth Rao
Our objective was to determine incidence, predisposing factors, and microbiological profile of urinary tract infection (UTI) in renal transplant recipients in our center. This was cross-sectional observational study, conducted at the Department of Nephrology, Army Hospital Research and Referral, Delhi, India. Two hundred and ten renal transplant recipients were studied over one year. Out of 210 transplant recipients, 69 (32.86%) had UTI. Majority (59/69) had undergone live renal transplantation and 10 cases had received cadaveric grafts...
March 2018: Saudi Journal of Kidney Diseases and Transplantation
https://www.readbyqxmd.com/read/29651798/long-term-persistence-with-mirabegron-in-a-real-world-clinical-setting
#4
Naoki Wada, Masaki Watanabe, Hiroko Banjo, Miyu Tsuchida, Junichi Hori, Gaku Tamaki, Makoto Azumi, Masafumi Kita, Hidehiro Kakizaki
OBJECTIVES: To examine the long-term persistence rate with mirabegron in a real-world clinical setting. METHODS: We retrospectively collected the data of patients who were prescribed mirabegron. We investigated the persistence rate and the reason for the discontinuation. The analysis included patient's age, diagnosis, Overactive Bladder Symptom Score, prostatic volume, the prescription by specialists for lower urinary tract dysfunction, drug-naïve patients, replacement of antimuscarinics or add-on therapy to antimuscarinics...
April 12, 2018: International Journal of Urology: Official Journal of the Japanese Urological Association
https://www.readbyqxmd.com/read/29619902/risk-factors-of-overactive-bladder-syndrome-and-its-relation-to-sexual-function-in-menopausal-women
#5
Sevil Hakimi, Elham Aminian, Sakineh Mohammad- Alizadeh Charandabi, Parvin Bastani, Marzieh Mohammadi
BACKGROUND: Overactive bladder syndrome is a common and annoying complication worldwide that could negatively affect the quality of life of afflicted individuals. We aimed to determine the prevalence and risk factors of overactive bladder syndrome and its relation to sexual function in healthy menopausal women. METHODS: This cross-sectional study was done on 340 women aged 45-60 years in Tabriz, northwest Iran, during 2015-2016. Data were collected using a demographic data questionnaire, the Overactive Bladder Syndrome Score, and the McCoy Female Sexuality Questionnaire...
February 2018: Urologia
https://www.readbyqxmd.com/read/29609420/efficacy-of-an-alpha-blocker-for-the-treatment-of-nonneurogenic-voiding-dysfunction-in-women-an-8-week-randomized-double-blind-placebo-controlled-trial
#6
Young-Suk Lee, Kyu-Sung Lee, Myung-Soo Choo, Joon Chul Kim, Jeong Gu Lee, Ju Tae Seo, Jeong Zoo Lee, Ji Youl Lee, Seung-June Oh, Yong Gil Na
PURPOSE: To evaluate the efficacy of an alpha-1 adrenergic receptor (α1-AR) blocker for the treatment of female voiding dysfunction (FVD) through a pressure-flow study. METHODS: This was a randomized, double-blind, placebo-controlled trial. Women aged ≥18 years with voiding symptoms, as defined by an American Urological Association symptom score (AUA-SS) ≥15 and a maximum flow rate (Qmax) <15 mL/sec with a voided volume of >100 mL and/or a postvoid residual (PVR) volume >150 mL, were randomly allocated to either the alfuzosin or placebo group...
March 2018: International Neurourology Journal
https://www.readbyqxmd.com/read/29603811/utility-of-catheterized-specimens-in-reducing-overdiagnosis-of-urinary-tract-infections-in-women
#7
Carrie M Aisen, Erica Ditkoff, Arindam RoyChoudhury, Michele Corish, Matthew P Rutman, Doreen E Chung, Gina M Badalato, Kimberly L Cooper
AIMS: To evaluate the utility of catheterized samples in reducing overdiagnosis of UTI based on voided specimens among patients presenting with a range of urinary symptoms. We also aimed to determine variables that may modify the predictive value of the voided midstream urine culture. METHODS: Patient charts were reviewed to identify female patients referred to our voiding dysfunction clinic with a range of complaints warranting urine studies (5/2014-8/2016). Patients with a positive voided urine culture who also had a catheterized urine culture in our system were included...
March 31, 2018: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/29603534/low-intensity-extracorporeal-shock-wave-therapy-ameliorates-diabetic-underactive-bladder-in-streptozocin-induced-diabetic-rats
#8
Hsun Shuan Wang, Byung Seok Oh, Bohan Wang, Yajun Ruan, Jun Zhou, Lia Banie, Yung Chin Lee, Arianna Tamaddon, Zhou Tie, Guifang Wang, Guiting Lin, Tom F Lue
OBJECTIVES: To evaluate the therapeutic effect of once-per-week low-intensity extracorporeal shock wave therapy (Li-ESWT) on underactive bladder (UAB) in the streptozotocin-induced diabetic rat model. MATERIALS AND METHODS: Thirty-six female Sprague-Dawley rats were assigned into 3 groups: normal control (NC), diabetes control (DMC), and diabetes underwent Li-ESWT (DM Li-ESWT). The two DM groups received intraperitoneal 60 mg/kg streptozotocin injection to induce diabetes mellitus...
March 30, 2018: BJU International
https://www.readbyqxmd.com/read/29603450/nerve-growth-factor-dependent-hyperexcitability-of-capsaicin-sensitive-bladder-afferent-neurones-in-mice-with-spinal-cord-injury
#9
Takahiro Shimizu, Tsuyoshi Majima, Takahisa Suzuki, Nobutaka Shimizu, Naoki Wada, Katsumi Kadekawa, Shun Takai, Eiichiro Takaoka, Joonbeom Kwon, Anthony J Kanai, William C de Groat, Pradeep Tyagi, Motoaki Saito, Naoki Yoshimura
Nerve growth factor (NGF) has been implicated as an important mediator to induce C-fibre bladder afferent hyperexcitability, which contributes to the emergence of neurogenic lower urinary tract dysfunction (LUTD) following spinal cord injury (SCI). In this study, we determined if NGF immunoneutralization using an anti-NGF antibody (NGF-Ab) normalizes the SCI-induced changes in electrophysiological properties of capsaicin-sensitive C-fibre bladder afferent neurones in female C57BL/6 mice. The spinal cord was transected at the Th8/9 level...
March 30, 2018: Experimental Physiology
https://www.readbyqxmd.com/read/29602711/tenofovir-disoproxil-fumarate-co-administered-with-lopinavir-ritonavir-is-strongly-associated-with-tubular-damage-and-chronic-kidney-disease
#10
Daisuke Mizushima, Dung Thi Hoai Nguyen, Dung Thi Nguyen, Shoko Matsumoto, Junko Tanuma, Hiroyuki Gatanaga, Nguyen Vu Trung, Nguyen van Kinh, Shinichi Oka
BACKGROUD: With expanding antiretroviral therapy (ART) in a resource-limited setting, the use of second line ART with ritonavir boosted lopinavir (LPV/r) is increasing. However, little is known regarding the renal safety of tenofovir (TDF) co-administered with LPV/r. METHODS: In total 1382 HIV-infected patients were enrolled and data were recorded twice (October 2014 and 2015) in Vietnam. Tubular dysfunction (TD) was defined as urinary beta 2 microglobulin (β2MG) > 1000 μg/L at both timepoints or increase in β2MG by > 2000 μg/L...
March 27, 2018: Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy
https://www.readbyqxmd.com/read/29575219/the-history-of-the-society-of-urodynamics-female-pelvic-medicine-and-urogenital-reconstruction
#11
Steven J Weissbart, Philippe E Zimmern, Victor W Nitti, Gary E Lemack, Kathleen C Kobashi, Sandip P Vasavada, Alan J Wein
AIMS: To review the history of the Society of Urodynamics, Female Pelvic Medicine and Urogenital Reconstruction (SUFU). METHODS: We reviewed Society meeting minutes, contacted all living former Society presidents, searched the William P. Didusch Center for Urology History records, and asked Society members to share their important Society experiences in order to gather important historical information about the Society. RESULTS: The Society initially formed as the Urodynamics Society in 1969 in the backdrop of a growing passion for scientific research in the country after World War II ended...
March 25, 2018: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/29568322/modelling-of-soft-connective-tissues-to-investigate-female-pelvic-floor-dysfunctions
#12
Aroj Bhattarai, Manfred Staat
After menopause, decreased levels of estrogen and progesterone remodel the collagen of the soft tissues thereby reducing their stiffness. Stress urinary incontinence is associated with involuntary urine leakage due to pathological movement of the pelvic organs resulting from lax suspension system, fasciae, and ligaments. This study compares the changes in the orientation and position of the female pelvic organs due to weakened fasciae, ligaments, and their combined laxity. A mixture theory weighted by respective volume fraction of elastin-collagen fibre compound (5%), adipose tissue (85%), and smooth muscle (5%) is adopted to characterize the mechanical behaviour of the fascia...
2018: Computational and Mathematical Methods in Medicine
https://www.readbyqxmd.com/read/29548713/cycling-and-female-sexual-and-urinary-function-results-from-a-large-multinational-cross-sectional-study
#13
Thomas W Gaither, Mohannad A Awad, Gregory P Murphy, Ian Metzler, Thomas Sanford, Michael L Eisenberg, Siobhan Sutcliffe, E Charles Osterberg, Benjamin N Breyer
BACKGROUND: Bicycle riding has become an increasingly popular mode of transportation and exercise, especially among women, and previous studies have demonstrated a relationship between cycling and sexual dysfunction, albeit using non-validated questionnaires. AIM: We aimed to explore the relationship between cycling and sexual and urinary dysfunction. METHODS: Cyclists were recruited to complete a survey through Facebook advertisements and outreach to sporting clubs across 5 English-speaking countries...
March 6, 2018: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/29539623/urine-proteomics-revealed-a-significant-correlation-between-urine-fibronectin-abundance-and-estimated-gfr-decline-in-patients-with-bardet-biedl-syndrome
#14
Marianna Caterino, Miriam Zacchia, Michele Costanzo, Giuliana Bruno, Davide Arcaniolo, Francesco Trepiccione, Rosa Anna Siciliano, Maria Fiorella Mazzeo, Margherita Ruoppolo, Giovambattista Capasso
BACKGROUND: /Aims: Renal disease is a common cause of morbidity in patients with Bardet-Biedl syndrome (BBS), however the severity of kidney dysfunction is highly variable. To date, there is little information on the pathogenesis, the risk and predictor factors for poor renal outcome in this setting. The present study aims to analyze the spectrum of urinary proteins in BBS patients, in order to potentially identify 1) disease-specific proteomic profiles that may differentiate the patients from normal subjects; 2) urinary markers of renal dysfunction...
March 8, 2018: Kidney & Blood Pressure Research
https://www.readbyqxmd.com/read/29521435/sexual-function-and-qualify-of-life-in-women-with-spina-bifida-are-the-women-with-spina-bifida-satisfied-with-their-sexual-activity
#15
Eun Kyoung Choi, Sang Woon Kim, Yoonhye Ji, Seoung-Wha Lim, Sang Won Han
AIMS: As the life expectancy of persons with spina bifida increases, sexual life in adulthood presents a considerable challenge for this population. The purpose of this study was to evaluate the sexual function of young women with spina bifida and its impact on their quality of life (QOL). METHODS: To assess sexual function and QOL by using self-administered questionnaires (Female Sexual Function Index [FSFI] and 36-Item Short Form Health Survey) in young women with spina bifida, we collected data from 44 young women with spina bifida between June 2013 and October 2013 at the spina bifida clinic of our hospital...
March 9, 2018: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/29520560/effects-of-combined-treatment-of-tadalafil-and-tamsulosin-on-bladder-dysfunction-via-the-inhibition-of-afferent-nerve-activities-in-a-rat-model-of-bladder-outlet-obstruction
#16
Akira Furuta, Yasuyuki Suzuki, Taro Igarashi, Yusuke Koike, Shin Egawa, Naoki Yoshimura
PURPOSE: To investigate the effects of combined treatment of tadalafil (a phosphodiesterase-5 inhibitor) and tamsulosin (an α1 -adrenoceptor antagonist) on bladder dysfunction in a rat model of bladder outlet obstruction (BOO). METHODS: Cystometry was performed in conscious female BOO rats 6 weeks after partially ligation of the urethra. Either tadalafil (0.03, 0.1 and 0.3 mg/kg) or tamsulosin (0.001, 0.003 and 0.01 mg/kg) was cumulatively applied intravenously at 30-min intervals to examine changes in cystometric parameters and blood pressures...
March 8, 2018: International Urology and Nephrology
https://www.readbyqxmd.com/read/29512088/sexual-dysfunction-in-married-women-with-urinary-incontinence
#17
Handan Zincir, Gokce Demir, Yurdagül Günaydin, Betül Ozen
PURPOSE: This study was conducted in descriptive and cross-sectional design in order to determine prevalence of urinary incontinence severity in women with urinary incontinence (UI), correlation between UI and sexual dysfunctionMaterials and Methods: The study had descriptive and cross-sectional design. In sample selection, four Family Health Centers areas were determined by lot and totally 384 women with UI were reached by making home visits in these regions. As data collection tool, severity index in female urinary incontinence determining UI condition and Female Sexual Function index determining sexual functioning were used...
March 7, 2018: Urology Journal
https://www.readbyqxmd.com/read/29504634/affective-symptoms-and-quality-of-life-in-patients-with-voiding-or-storage-dysfunction-results-before-and-after-sacral-neuromodulation-a-prospective-follow-up-study
#18
Ranjana Jairam, Jamie Drossaerts, Desiree Vrijens, Carsten Leue, Philip van Kerrebroeck, Gommert van Koeveringe
AIMS: Sacral neuromodulation (SNM) is an effective treatment for patients with overactive bladder syndrome (OAB) or non-obstructive urinary retention (NOR). These lower urinary tract symptoms (LUTS) are the result of a functional urological cause but often coincide with psychological and/or psychiatric factors. It has been stated that there is an association between LUTS, depression and anxiety disorders. With this study we will investigate whether affective symptoms and quality of life (QoL) improve after successful SNM...
March 5, 2018: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/29500487/long-term-functional-outcomes-of-perineal-gangrene-worse-than-expected-an-observational-retrospective-study
#19
A Le Fouler, A Hamy, J Barbieux, V Souday, P Bigot, P Le Naoures, R Jaouen, C Brochard, Aurélien Venara
PURPOSE: For survivors of perineal gangrene (PG), quality of life and functional prognosis of pelvic functions are probably overestimated. The aim of this study was to report long-term anal and urinary sphincter dysfunctions, sexual sequelae, and patients' quality of life after treatment of perineal gangrene. METHODS: This retrospective observational study was conducted in one university hospital over 16 years. Seventy-three patients experienced PG; 22 were subject to long-term follow-up...
March 2, 2018: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/29494351/sexual-satisfaction-changes-reported-by-men-after-their-partners-robotic-assisted-laparoscopic-sacrocolpopexies
#20
Patrick J Culligan, Sean Haughey, Christa Lewis, Jennifer Priestley, Charbel Salamon
OBJECTIVES: This study aimed to compare the preoperative and postoperative sexual satisfaction reported by male sexual partners of women undergoing surgical correction of pelvic organ prolapse. METHODS: This was a single-center prospective cohort study. Heterosexual, sexually active English-speaking couples in which the women were planning to undergo robotic-assisted laparoscopic sacrocolpopexy for correction of pelvic organ prolapse were eligible for enrollment in the study...
March 1, 2018: Female Pelvic Medicine & Reconstructive Surgery
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