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Female urinary dysfunction

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https://www.readbyqxmd.com/read/27887914/practical-and-functional-classification-of-the-double-urethra-a-variable-complex-and-fascinating-malformation-observed-in-20-patients
#1
M Lima, F Destro, M Maffi, D Persichetti Proietti, G Ruggeri
INTRODUCTION: Urethral duplication is a rare and variable malformation of the urinary tract, with non-univocal and complex management. In addition, different classification schemes have been proposed, but none have considered all the possible variants. OBJECTIVE: To report experience with the management of 20 urethral duplication patients and propose a classification of this anomaly. MATERIALS AND METHODS: A retrospective analysis collecting information regarding 20 patients (Table) with urethral duplication treated at a single institution over the past 40 years...
November 3, 2016: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/27887601/protocol-for-a-prospective-randomized-study-on-neurophysiological-assessment-of-lower-urinary-tract-function-in-a-healthy-cohort
#2
Stéphanie van der Lely, Martina Stefanovic, Melanie R Schmidhalter, Marta Pittavino, Reinhard Furrer, Martina D Liechti, Martin Schubert, Thomas M Kessler, Ulrich Mehnert
BACKGROUND: Lower urinary tract symptoms are highly prevalent and a large proportion of these symptoms are known to be associated with a dysfunction of the afferent pathways. Diagnostic tools for an objective and reproducible assessment of afferent nerve function of the lower urinary tract are missing. Previous studies showed first feasibility results of sensory evoked potential recordings following electrical stimulation of the lower urinary tract in healthy subjects and patients. Nevertheless, a refinement of the methodology is necessary...
November 25, 2016: BMC Urology
https://www.readbyqxmd.com/read/27828991/loss-of-mecp2-causes-urological-dysfunction-and-contributes-to-death-by-kidney-failure-in-mouse-models-of-rett-syndrome
#3
Christopher S Ward, Teng-Wei Huang, José A Herrera, Rodney C Samaco, Meagan R Pitcher, Alan Herron, Steven A Skinner, Walter E Kaufmann, Daniel G Glaze, Alan K Percy, Jeffrey L Neul
Rett Syndrome (RTT) is a neurodevelopmental disorder characterized by loss of acquired skills during development, autonomic dysfunction, and an increased risk for premature lethality. Clinical experience identified a subset of individuals with RTT that present with urological dysfunction including individuals with frequent urinary tract infections, kidney stones, and urine retention requiring frequent catheterization for bladder voiding. To determine if urologic dysfunction is a feature of RTT, we queried the Rett Syndrome Natural History Study, a repository of clinical data from over 1000 individuals with RTT and found multiple instances of urological dysfunction...
2016: PloS One
https://www.readbyqxmd.com/read/27824705/correlation-between-echodefecography-and-3-dimensional-vaginal-ultrasonography-in-the-detection-of-perineal-descent-in-women-with-constipation-symptoms
#4
Sthela M Murad-Regadas, Francisco Sergio Pinheiro Regadas, Lusmar V Rodrigues, Adjra da Silva Vilarinho, Guilherme Buchen, Livia Olinda Borges, Lara B Veras, Mariana Murad da Cruz
BACKGROUND: Defecography is an established method of evaluating dynamic anorectal dysfunction, but conventional defecography does not allow for visualization of anatomic structures. OBJECTIVE: The purpose of this study was to describe the use of dynamic 3-dimensional endovaginal ultrasonography for evaluating perineal descent in comparison with echodefecography (3-dimensional anorectal ultrasonography) and to study the relationship between perineal descent and symptoms and anatomic/functional abnormalities of the pelvic floor...
December 2016: Diseases of the Colon and Rectum
https://www.readbyqxmd.com/read/27807040/a-combined-intervention-of-zinc-multiple-micronutrients-and-albendazole-does-not-ameliorate-environmental-enteric-dysfunction-or-stunting-in-rural-malawian-children-in-a-double-blind-randomized-controlled-trial
#5
Alfred Z Wang, Robert J Shulman, Audrey H Crocker, Chrissie Thakwalakwa, Kenneth M Maleta, Sridevi Devaraj, Mark J Manary, Indi Trehan
BACKGROUND: Environmental enteric dysfunction (EED) and linear growth stunting affect many rural agrarian children in the developing world and contribute to the persistently high rates of stunting that are observed worldwide. Effective interventions to consistently ameliorate EED are lacking. OBJECTIVE: We tested whether a bundle of safe and affordable interventions would decrease EED and stunting over 12-24 wk in a cohort of rural Malawian children 12-35 mo old...
November 2, 2016: Journal of Nutrition
https://www.readbyqxmd.com/read/27797333/-the-effect-of-sulodexide-on-placental-mitochondria-function-in-rats-with-experimental-preeclampsia
#6
T A Popova, V N Perfilova, G A Zhakupova, V E Verovsky, O V Ostrovskij, I N Tyurenkov
Substitution of drinking water for 1.8% NaCl in pregnant rats caused a pronounced increase in arterial pressure by 24,3% and urinary protein by 117% to day 21 of pregnancy. State 4 respiration of isolated placental mitochondria in the group of negative control was 3- and 1.5-fold higher with malate/glutamate and succinate as substrates than in placental mitochondria isolated from uncomplicated pregnant animals. This led to a decrease of the respiratory control ratio. These results suggest that development of experimental preeclampsia is accompanied by mitochondrial dysfunction through uncoupling of oxidative phosphorylation...
July 2016: Biomedit︠s︡inskai︠a︡ Khimii︠a︡
https://www.readbyqxmd.com/read/27794188/impaired-contractility-of-the-circular-striated-urethral-sphincter-muscle-may-contribute-to-stress-urinary-incontinence-in-femal-zucker-fatty-rats
#7
Yung-Chin Lee, Guiting Lin, Guifang Wang, Amanda Reed-Maldonado, Zhihua Lu, Lin Wang, Lia Banie, Tom F Lue
AIM: Obesity has been an independent risk factor for female stress urinary incontinence (SUI), the mechanism of this association remains unknown. The aim of this study is to validate the hypothesis that urethral dysfunction is a possible contributor to SUI in obese women. METHODS: Ten Zucker Fatty (ZF) (ZUC-Lepr(fa) 185) and 10 Zucker Lean (ZL) (ZUC-Lepr(fa) 186) female rats at 12-week-old were used in this experiment. The urethral sphincter rings were harvested from the bladder neck through to the most proximal 2/3 regions...
October 29, 2016: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/27792116/characteristics-of-residual-symptoms-following-laminoplasty-in-diabetic-patients-with-cervical-spondylotic-myelopathy-a-prospective-cohort-study
#8
Masaaki Machino, Shiro Imagama, Kei Ando, Kazuyoshi Kobayashi, Tetsuro Hida, Kenyu Ito, Mikito Tsushima, Akiyuki Matsumoto, Satoshi Tanaka, Masayoshi Morozumi, Keigo Ito, Fumihiko Kato, Yoshihiro Nishida, Naoki Ishiguro
STUDY DESIGN: A prospective cohort study OBJECTIVE.: The purpose of this study was to compare cervical laminoplasty outcomes between diabetic and non-diabetic patients with cervical spondylotic myelopathy (CSM), and to characterize residual symptoms of diabetic patients. METHODS: A total of 505 consecutive patients with CSM (331 males, 189 females; mean age, 66.6 years; range, 41-91 years; > 1-year follow-up after laminoplasty) were enrolled and divided into diabetic group (n = 105) and non-diabetic group (n = 400)...
October 25, 2016: Spine
https://www.readbyqxmd.com/read/27780812/the-impact-of-abdominal-contouring-with-monsplasty-on-sexual-function-and-urogenital-distress-in-women-following-massive-weight-loss
#9
Michael R Bykowski, J Peter Rubin, Jeffrey A Gusenoff
BACKGROUND: Monsplasty treats massive weight loss (MWL) patients with redundant tissues in the mons region. Monsplasty, however, is not a routine component of abdominal contouring. OBJECTIVES: The goal of this study was to evaluate the changes in urinary and sexual functioning in patients who undergo abdominal contouring with monsplasty vs non-operated controls. METHODS: A prospective study was performed of patients who underwent abdominal contouring + monsplasty or no surgery...
October 25, 2016: Aesthetic Surgery Journal
https://www.readbyqxmd.com/read/27778376/post-injury-bladder-management-strategy-influences-lower-urinary-tract-dysfunction-in-the-mouse-model-of-spinal-cord-injury
#10
Naoki Wada, Takahiro Shimizu, Shun Takai, Nobutaka Shimizu, Anthony J Kanai, Pradeep Tyagi, Hidehiro Kakizaki, Naoki Yoshimura
AIMS: To examine the effects of a different number of daily bladder squeezes on bladder dysfunction in mice with spinal cord injury (SCI). METHODS: Spinal cord was transected at the Th8/9 in female C57BL/6N mice. Their bladders were manually squeezed to eliminate urine inside every day for 4 weeks. The mice were divided into three groups depending on the number of bladder squeezes; A: once daily, B: twice daily, C: three times daily. Four weeks after transection, single-filling cystometry were performed under an awake condition...
October 24, 2016: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/27774877/genitourinary-complications-of-diabetes-mellitus-an-overview-of-pathogenesis-evaluation-and-management
#11
Jason Gandhi, Gautam Dagur, Kelly Warren, Noel Smith, Sardar Ali Khan
BACKGROUND: Diabetes mellitus is a vastly prevalent metabolic disorder with escalating global health concerns. Particularly when mismanaged, chronic micro- and macrovascular complications may highly impair physiological systems while immunodeficiency disposes us to infection. OBJECTIVE: We investigate infections, localized complications, and neoplasms of the genitourinary system secondary to the chronic complications of diabetes mellitus in males and females. METHOD: A comprehensive MEDLINE® search was guided using key words relevant to diabetes mellitus and the genitourinary system...
October 19, 2016: Current Diabetes Reviews
https://www.readbyqxmd.com/read/27757396/feasibility-of-transanal-endoscopic-total-mesorectal-excision-for-rectal-cancer-results-of-a-pilot-study
#12
Jae Hwan Oh, Sung Chan Park, Min Jung Kim, Byung Kwan Park, Jong Hee Hyun, Hee Jin Chang, Kyung Su Han, Dae Kyung Sohn
PURPOSE: To evaluate the feasibility of transanal total mesorectal excision (TME) in patients with rectal cancer. METHODS: This study enrolled 12 patients with clinically node negative rectal cancer located 4-12 cm from the anal verge who underwent transanal endoscopic TME with the assistance of single port laparoscopic surgery between September 2013 and August 2014. The primary endpoint was TME quality; secondary endpoints included number of harvested lymph nodes and postoperative complications within 30 days (NCT01938027)...
October 2016: Annals of Surgical Treatment and Research
https://www.readbyqxmd.com/read/27734726/intermittent-self-catheterisation-for-urolgical-problems-caused-by-fgm
#13
Debbie Duncan
This is the fourth and final article in a series on female genital mutilation (FGM). It describes the complications of FGM, with a focus on the urinary ones. FGM refers to all procedures that involve partial or total removal of the external female genitalia and/or damage to other female genital organs for non-medical reasons. The World Health Organization (WHO) has classified FGM into four types (1-4). Women who have type 3 commonly experience long-term complications of their urological tract. The first-line treatment for type 3 FGM involves surgical defibulation, but this is not always successful and women can be left with neurogenic bladder dysfunction and urethral stricture disease...
October 13, 2016: British Journal of Nursing: BJN
https://www.readbyqxmd.com/read/27706125/the-impact-of-nocturnal-polyuria-in-older-people-with-nocturnal-luts
#14
Ana L Lopes Mendes, Veerle Decalf, Marie A Denys, Andrea Tubaro, Karel Everaert
BACKGROUND: Bladder dysfunctions often express the presence of lower urinary tract symptoms (LUTS) and are common in older people. Aim of this study is to analyse the Micturition, Incontinence and Residual in older people, evaluating the role of Nocturnal Polyuria. METHODS: 86 patients with at least 65 years old and invalidating LUTS were hospitalized for 24 hours. The Maximum Bladder Capacity, mean Micturition Volume, Post Voiding Residual and Incontinence Volume were recorded and analysed day-time and night-time...
October 5, 2016: Minerva Urologica e Nefrologica, the Italian Journal of Urology and Nephrology
https://www.readbyqxmd.com/read/27706006/percutaneous-nerve-evaluation-test-versus-staged-test-trials-for-sacral-neuromodulation-sensitivity-specificity-and-predictive-values-of-each-technique
#15
Mai Banakhar, Magdy Hassouna
PURPOSE: InterStim device is an U.S. Food and Drug Administration approved minimal invasive therapy for sacral neuromodulation for lower urinary tract dysfunction. Before InterStim implantation, a trial with the appropriate screening tests is required to determine patient therapy eligibility. There are two different techniques for patient screening: percutaneous nerve evaluation (PNE) test and staged test. Few studies have reported success and failure rates for each technique. However, test sensitivity and predictive values of either test have not been studied...
September 2016: International Neurourology Journal
https://www.readbyqxmd.com/read/27704153/in-the-footsteps-of-bonney-and-nichols-hysterectomy-during-surgical-repair-of-pelvic-organ-prolapse
#16
Maurizio Serati, Diaa Rizk, Stefano Savatore
Based on the available urogynecological literature, the role of hysterectomy in the surgical strategy of pelvic organ prolapse (POP) repair remains controversial. Currently, there are no data to favor either the removal or preservation of the uterus in women with POP. The findings that hysterectomy may contribute to a higher success rate and to the development of urinary incontinence and/or female sexual dysfunction are not supported by evidence. It is not clear why both hysteropexy was sometimes performed in the presence of overt uterine prolapse and/or concomitant vaginal hysterectomy was often included in vaginal prolapse repair in the absence of uterine prolapse...
October 4, 2016: International Urogynecology Journal
https://www.readbyqxmd.com/read/27686568/expressions-of-vaginal-endothelial-nitric-oxide-synthase-and-phosphodiesterase-5-in-female-sexual-dysfunction-a-pilot-study
#17
Kang Jun Cho, Kyu-Sung Lee, Myung-Soo Choo, Ju Tae Seo, Jang Hwan Kim, Jong Bo Choi, Seung-June Oh, Joon Chul Kim
INTRODUCTION AND HYPOTHESIS: The objective was to investigate the expression of endothelial nitric oxide synthase (eNOS) and phosphodiesterase (PDE) 5 in vaginal tissue of premenopausal women experiencing stress urinary incontinence (SUI) with and without sexual dysfunction. METHODS: Women presenting for treatment of SUI were screened using the Female Sexual Function Index (FSFI) and 10 were selected who met the criteria for female sexual dysfunction (FSD) and 10 asymptomatic controls...
September 29, 2016: International Urogynecology Journal
https://www.readbyqxmd.com/read/27664581/functional-magnetic-resonance-imaging-with-concurrent-urodynamic-testing-identifies-brain-structures-involved-in-micturition-cycle-in-patients-with-multiple-sclerosis
#18
Rose Khavari, Christof Karmonik, Michael Shy, Sophie Fletcher, Timothy Boone
PURPOSE: Neurogenic Lower Urinary Tract Dysfunction (NLUTD) is common in multiple sclerosis (MS) patients with a significant impact on their quality of life. In this study, we seek to discover brain activity processes during the micturition cycle in female patients with MS and NLUTD. MATERIALS AND METHODS: We report brain activity via functional magnetic resonance imaging (fMRI) and simultaneous urodynamic testing (UDS) in twenty-three ambulatory female patients with MS...
September 21, 2016: Journal of Urology
https://www.readbyqxmd.com/read/27649461/female-sexual-dysfunction-post-radical-cystectomy-and-urinary-diversion
#19
M H Zahran, O Fahmy, A S El-Hefnawy, B Ali-El-Dein
OBJECTIVES: To evaluate the impact of radical cystectomy and urinary diversion on female sexual function. MATERIALS AND METHODS: A Medline search was conducted according to the PRISMA statement for all English full-text articles published between 1980 and 2016 and assessing female sexual function post radical cystectomy and urinary diversion. Eligible studies were subjected to critical analysis and revision. The primary outcomes were the reporting methods for female sexual dysfunction (FSD), manifestations of FSD, and factors associated with FSD, postoperative recoverability of FSD, and awareness level regarding FSD...
September 20, 2016: Climacteric: the Journal of the International Menopause Society
https://www.readbyqxmd.com/read/27605559/%C3%AE-1d-adrenoceptor-blockade-increases-voiding-efficiency-by-improving-external-urethral-sphincter-activity-in-rats-with-spinal-cord-injury
#20
Hirokazu Ishida, Hiroki Yamauchi, Hideaki Ito, Hironobu Akino, Osamu Yokoyama
PURPOSE: Ideal therapy for lower urinary tract dysfunction in patients with spinal cord injury (SCI) should decrease detrusor overactivity, thereby promoting urine storage at low intravesical pressure and promoting efficient voiding at low pressure by decreasing detrusor-sphincter dyssynergia. Here we investigated blockade of various α1-adrenoceptors to determine the subtype that was principally responsible for improving the voiding dysfunction. MATERIALS AND METHODS: The effects of the intravenous α1A/D-blocker naftopidil, the α1D-blocker BMY 7378, and the α1A-blocker silodosin were evaluated using cystometrography and external urethral sphincter-electromyography (EMG) in decerebrated, unanesthetized female Sprague-Dawley rats with chronic SCI following transection at Th8...
September 7, 2016: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology
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