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Female urinary dysfunction

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https://www.readbyqxmd.com/read/29454543/characterization-of-the-passive-and-active-material-parameters-of-the-pubovisceralis-muscle-using-an-inverse-numerical-method
#1
M E T Silva, M P L Parente, S Brandão, T Mascarenhas, R M Natal Jorge
The mechanical characteristics of the female pelvic floor are relevant to understand pelvic floor dysfunctions (PFD), and how they are related with changes in their biomechanical behavior. Urinary incontinence (UI) and pelvic organ prolapse (POP) are the most common pathologies, which can be associated with changes in the mechanical properties of the supportive structures in the female pelvic cavity. PFD have been studied through different methods, from experimental tensile tests using tissues from fresh female cadavers or tissues collected at the time of a transvaginal hysterectomy procedure, or by applying imaging techniques...
February 8, 2018: Journal of Biomechanics
https://www.readbyqxmd.com/read/29416500/msa-mimic-rare-occurrence-of-anti-hu-autonomic-failure-and-thymoma-in-a-patient-with-parkinsonism-case-report-and-literature-review
#2
Vito A G Ricigliano, Barbara Fossati, Lorenzo Saraceno, Michele Cavalli, Elena Bazzigaluppi, Giovanni Meola
Thymoma is a tumor originating from thymic gland, frequently manifesting with paraneoplastic neurological disorders. Its association with paraneoplastic dysautonomia is relatively uncommon. Here, we describe the challenging case of a 71 year-old female who developed subacute autonomic failure with digestive pseudo-obstruction, dysphagia, urinary tract dysfunction and orthostatic hypotension complicating an underlying extrapyramidal syndrome that had started 3 months before hospital admission. Autonomic symptoms had 2-month course and acutely worsened just before and during hospitalization...
2018: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/29406060/female-voiding-dysfunction-and-urinary-incontinence
#3
REVIEW
Amanda Vo, Stephanie J Kielb
Female voiding dysfunction and incontinence are common in the general population and symptoms have been shown to have a significant negative impact on health-related quality of life. This article highlights the epidemiology, evaluation, diagnosis, pharmacologic therapies, and surgical treatment for overactive bladder, stress urinary incontinence, and urogenital fistulas.
March 2018: Medical Clinics of North America
https://www.readbyqxmd.com/read/29390218/-surgical-treatment-of-pelvic-organ-prolapse
#4
Leonidas Karapanos, Johannes Salem, Ilgar Akbarov, Axel Heidenreich, Vahudin Zugor
Female pelvic organ prolapse is a widely prevalent condition and is associated with variable morbidity. It encompasses a number of clinical conditions, including subvesical obstruction, overactive bladder symptoms, sexual dysfunction and urinary und fecal incontinence. The prevalence of pelvic insufficiency is estimated to be between 30 and 50 %. As life expectancy is increasing and the elderly population is growing, there will be an increased incidence of the condition and growing demand for pelvic floor treatment in the future...
February 2018: Aktuelle Urologie
https://www.readbyqxmd.com/read/29376236/-treatment-of-anovulatory-infertility-by-tonifying-kidney-and-promoting-blood-circulation
#5
Kun Ma, Ya-Jing Tong
Infertility is a common disease in women of childbearing age and is also a refractory disease. Anovulatory dysfunction is one of the main causes of female infertility, and the incidence of anovulatory infertility has been increasing year by year. Traditional Chinese medicine has unique advantages and definite curative effect on the treatment of this disease. Kidney deficiency is the basic pathogenesis and blood stasis is an important factor that has been through. Flexible of tonifying the kidney and promoting blood circulation treatment of anovulatory infertility in clinic, has achieved remarkable curative effect...
December 2017: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/29372089/a-case-of-persistent-urogenital-sinus-pitfalls-and-challenges-in-diagnosis
#6
Hooi H Tan, Shung K Tan, Rajah Shunmugan, Rozman Zakaria, Zakaria Zahari
Persistent urogenital sinus (PUGS) is a rare anomaly whereby the urinary and genital tracts fail to separate during embryonic development. We report a three-year-old female child who was referred to the Sabah Women & Children Hospital, Sabah, Malaysia, in 2016 with a pelvic mass. She had been born prematurely at 36 gestational weeks via spontaneous vaginal delivery in 2013 and initially misdiagnosed with neurogenic bladder dysfunction. The external genitalia appeared normal and an initial sonogram and repeat micturating cystourethrograms did not indicate any urogenital anomalies...
November 2017: Sultan Qaboos University Medical Journal
https://www.readbyqxmd.com/read/29333618/age-associated-urethral-dysfunction-in-urethane-anesthetized-rats
#7
Ryu Kimura, Minoru Miyazato, Asuka Ashikari, Takuma Oshiro, Seiichi Saito
AIMS: We aimed to investigate the age-associated changes in movement coordination between the urinary bladder and the urethra in rats. METHODS: A total of 17 female Sprague-Dawley rats were used. The rats were divided into young (3 months old) and middle-aged (12-15 months old) groups. In both groups, isovolumetric cystometry and urethral perfusion pressure (UPP) measurements were performed under urethane anesthesia. After the rhythmic bladder contractions stabilized, L-arginine, a nitric oxide (NO) substrate (100 mg/kg), was administered intravenously in both groups...
January 15, 2018: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/29320316/translabial-us-and-dynamic-mr-imaging-of-the-pelvic-floor-normal-anatomy-and-dysfunction
#8
Luciana P Chamié, Duarte Miguel Ferreira Rodrigues Ribeiro, Angela H M Caiado, Gisele Warmbrand, Paulo C Serafini
Pelvic floor dysfunction (PFD) is a common condition that typically affects women older than 50 years and decreases the quality of life. Weakening of support structures can involve all three pelvic compartments and cause a combination of symptoms, including constipation, urinary and fecal incontinence, obstructed defecation, pelvic pain, perineal bulging, and sexual dysfunction. The causes of PFD are complex and multifactorial; however, vaginal delivery is considered a major predisposing factor. Physical examination alone is limited in the evaluation of PFD; it frequently leads to an underestimation of the involved compartments...
January 2018: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/29285288/synthetic-nickel-containing-superoxide-dismutase-attenuates-para-phenylenediamine-induced-bladder-dysfunction-in-rats
#9
Bing-Juin Chiang, Tien-Wen Chen, Shiu-Dong Chung, Way-Zen Lee, Chiang-Ting Chien
Para (p)-phenylenediamine and its toxic metabolites induce excess reactive oxygen species formation that results in bladder voiding dysfunction. We determined the effects of synthetic Ni-containing superoxide dismutase mimics and the role of oxidative stress in p-phenylenediamine-induced urinary bladder dysfunction. P-phenylenediamine (60 μg/kg/day) was intraperitoneally administered for 4 weeks to induce bladder injury in female Wistar rats. Synthetic Ni-containing superoxide dismutase mimics, WCT003 (1.5 mg/kg) and WCT006 (1...
December 1, 2017: Oncotarget
https://www.readbyqxmd.com/read/29282207/risk-factors-for-the-development-of-bladder-and-bowel-dysfunction
#10
Thomas W Gaither, Christopher S Cooper, Zachary Kornberg, Laurence S Baskin, Hillary L Copp
BACKGROUND: Patients with vesicoureteral reflux and concomitant bladder and bowel dysfunction (BBD) are at high risk for febrile urinary tract infections. Risk factors for BBD have been identified in retrospective studies without validated measures. METHODS: We conducted a secondary analysis of the Randomized Intervention for Children with Vesicoureteral Reflux and Careful Urinary Tract Infection Evaluation trials. The outcome of interest in the analysis of these children was the development of BBD, defined by using the dysfunctional voiding questionnaire, during any time point in the studies...
January 2018: Pediatrics
https://www.readbyqxmd.com/read/29273944/health-status-of-polish-children-and-adolescents-after-cancer-treatment
#11
Krawczuk-Rybak Maryna, Panasiuk Anna, Stachowicz-Stencel Teresa, Zubowska Małgorzata, Skalska-Sadowska Jolanta, Sęga-Pondel Dorota, Czajńska-Deptuła Aneta, Sławińska Dorota, Badowska Wanda, Kamieńska Elżbieta, Pobudejska-Pieniążek Aneta, Wieczorek Maria
In the last 40 years, considerable progress was made in the treatment of childhood cancer. Nearly 80% of children achieve long-term clinical remission or are permanently cured. This improvement is however not without sacrifice. This is the first Polish study analyzing the general health status and epidemiology of organ late effects in the cohort of Polish childhood and adolescent cancer survivors monitored by doctors and registered in the on-line national database for late effects (N = 1761). This tool collects information on previous therapy and current health status (medical history, physical examination, laboratory tests) of cancer survivors...
December 22, 2017: European Journal of Pediatrics
https://www.readbyqxmd.com/read/29244860/lithium-reduces-blood-glucose-levels-but-aggravates-albuminuria-in-btbr-ob-ob-mice
#12
Theun de Groot, Lars Damen, Leanne Kosse, Mohammad Alsady, Rosalinda Doty, Ruben Baumgarten, Susan Sheehan, Johan van der Vlag, Ron Korstanje, Peter M T Deen
Glycogen synthase kinase 3 (GSK3) plays an important role in the development of diabetes mellitus and renal injury. GSK3 inhibition increases glucose uptake in insulin-insensitive muscle and adipose tissue, while it reduces albuminuria and glomerulosclerosis in acute kidney injury. The effect of chronic GSK3 inhibition in diabetic nephropathy is not known. We tested the effect of lithium, the only clinical GSK3 inhibitor, on the development of diabetes mellitus and kidney injury in a mouse model of diabetic nephropathy...
2017: PloS One
https://www.readbyqxmd.com/read/29241925/a-community-based-epidemiological-survey-of-overactive-bladder-and-voiding-dysfunction-in-female-taiwanese-residents-aged-40-years-and-above
#13
Soo-Cheen Ng, Suh-Woan Hu, Gin-Den Chen
OBJECTIVE: This is part of a three-year study designed to evaluate the natural history of lower urinary tract symptoms in local community residents aged 40 years and above in central Taiwan. We evaluated the prevalence of overactive bladder (OAB) and voiding dysfunction (VD) in female residents using validated questionnaires. MATERIALS AND METHODS: A structured questionnaire containing groups of different questionnaires was translated into Chinese and each one was validated separately...
December 2017: Taiwanese Journal of Obstetrics & Gynecology
https://www.readbyqxmd.com/read/29238748/non-motor-symptoms-in-progressive-supranuclear-palsy-prevalence-and-severity
#14
Fabiana Giada Radicati, Pablo Martinez Martin, Chiara Fossati, Kallol Ray Chaudhuri, Margherita Torti, Carmen Rodriguez Blazquez, Laura Vacca, Fabrizio Stocchi
NMSs have been extensively studied in PD patients but not in other forms of parkinsonism such as Progressive Supranuclear Palsy (PSP). The primary objective of this study was to analyze the frequency, severity and the type of non-motor symptoms (NMS) in PSP patients using the non-motor symptoms scale (NMSS). The secondary objective was to differentiate NMS between PSP and Parkinson's disease (PD). We enrolled in this cross-sectional study 50 consecutive PSP and 100 matched Parkinson's disease (PD) patients, in the proportion PSP/PD = 1/2, matched in age, sex, and disease duration...
2017: NPJ Parkinson's Disease
https://www.readbyqxmd.com/read/29238702/clinical-usefulness-of-urine-cytology-in-the-detection-of-bladder-tumors-in-patients-with-neurogenic-lower-urinary-tract-dysfunction
#15
Jürgen Pannek, Franziska Rademacher, Jens Wöllner
Introduction: Screening for bladder cancer in patients with neurogenic lower urinary tract dysfunction is a challenge. Cystoscopy alone is not sufficient to detect bladder tumors in this patient group. We investigated the usefulness of combined cystoscopy and urine cytology. Materials and methods: By a systematic chart review, we identified all patients with neurogenic lower urinary tract dysfunction who underwent combined cystoscopy and urine cytology testing. In patients with suspicious findings either in cytology or cystoscopy, transurethral resection was performed...
2017: Research and Reports in Urology
https://www.readbyqxmd.com/read/29237999/the-relationships-among-hyperuricemia-body-mass-index-and-impaired-renal-function-in-type-2-diabetic-patients
#16
Yongmei Li, Xing Fan, Chunjun Li, Xinyue Zhi, Liyuan Peng, Hongling Han, Bei Sun
Chronic kidney disease (CKD) is a common chronic microvascular complication and the major cause of death in diabetic patients. This study was conceived to explore the possible mechanisms of how hyperuricemia and obesity contribute to renal function impairment in type 2 diabetic (T2DM) patients. A cross-sectional study in 609 participants recruited from a T2DM population in North China was conducted. The multiplicative interaction between body mass index (BMI) and uric acid (UA) level was assessed using an interaction term in a logistic regression analysis...
December 13, 2017: Endocrine Journal
https://www.readbyqxmd.com/read/29218698/risk-factors-of-overactive-bladder-syndrome-and-its-relation-to-sexual-function-in-menopausal-women
#17
Sevil Hakimi, Elham Aminian, Sakineh Mohammad- Alizadeh Charandabi, Parvin Bastani, Marzieh Mohammadi
BACKGROUND: Overactive bladder syndrome is a common and annoying complication worldwide that could negatively affect the quality of life of afflicted individuals. We aimed to determine the prevalence and risk factors of overactive bladder syndrome and its relation to sexual function in healthy menopausal women. METHODS: This cross-sectional study was done on 340 women aged 45-60 years in Tabriz, northwest Iran, during 2015-2016. Data were collected using a demographic data questionnaire, the Overactive Bladder Syndrome Score, and the McCoy Female Sexuality Questionnaire...
December 4, 2017: Urologia
https://www.readbyqxmd.com/read/29214305/cardiovascular-outcomes-according-to-urinary-albumin-and-kidney-disease-in-patients-with-type-2-diabetes-at-high-cardiovascular-risk-observations-from-the-savor-timi-53-trial
#18
Benjamin M Scirica, Ofri Mosenzon, Deepak L Bhatt, Jacob A Udell, Ph Gabriel Steg, Darren K McGuire, KyungAh Im, Estella Kanevsky, Christina Stahre, Mikaela Sjöstrand, Itamar Raz, Eugene Braunwald
Importance: An elevated level of urinary albumin to creatinine ratio (UACR) is a marker of renal dysfunction and predictor of kidney failure/death in patients with type 2 diabetes. The prognostic use of UACR in established cardiac biomarkers is not well described. Objective: To evaluate whether UACR offers incremental prognostic benefit beyond risk factors and established plasma cardiovascular biomarkers. Design, Setting, and Participants: The Saxagliptin Assessment of Vascular Outcomes Recorded in Patients With Diabetes Mellitus-Thrombolysis in Myocardial Infarction (SAVOR-TIMI) 53 study was performed from May 2010 to May 2013 and evaluated the safety of saxagliptin vs placebo in patients with type 2 diabetes with overt cardiovascular disease or multiple risk factors...
December 6, 2017: JAMA Cardiology
https://www.readbyqxmd.com/read/29211350/the-angiotensin-ii-receptors-type-1-blockage-affects-the-urinary-bladder-activity-in-hyperosmolar-induced-detrusor-overactivity-in-rats-preliminary-results
#19
Kajetan Juszczak, Piotr Maciukiewicz
BACKGROUND: Angiotensin II receptors play a role in the pathogenesis of urinary bladder dysfunction, especially in the case of bladder outlet obstruction. The function of these receptors in the detrusor overactivity (DO) still remains unclear. OBJECTIVES: The study aims to investigate some of the mechanisms through which hyperosmolarity induces urinary bladder overactivity. The effect of angiotensin II receptor type 1 - AT1 (telmisartan) on urinary bladder function in physiological state and in hyperosmolar-induced DO in rat model was explored...
October 2017: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
https://www.readbyqxmd.com/read/29209135/first-case-of-cross-auxiliary-double-domino-donor-liver-transplantation
#20
Zhi-Jun Zhu, Lin Wei, Wei Qu, Li-Ying Sun, Ying Liu, Zhi-Gui Zeng, Liang Zhang, En-Hui He, Hai-Ming Zhang, Ji-Dong Jia, Zhong-Tao Zhang
We report a case of double domino liver transplantation in a 32-year-old woman who was diagnosed with familial amyloid polyneuropathy (FAP) and liver dysfunction. A two-stage surgical plan was designed, and one domino graft was implanted during each stage. During the first stage, an auxiliary domino liver transplantation was conducted using a domino graft from a 4-year-old female child with Wilson's disease. After removing the right lobe of the FAP patient's liver, the graft was rotated 90 degrees counterclockwise and placed along the right side of the inferior vena cava (IVC)...
November 28, 2017: World Journal of Gastroenterology: WJG
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