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Anterior Ischemic Optic Neuropathy

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https://www.readbyqxmd.com/read/28781891/vascular-occlusions-following-ocular-surgical-procedures-a-clinical-observation-of-vascular-complications-after-ocular-surgery
#1
Charlotte Fischer, Anne Bruggemann, Annette Hager, Josep Callizo Planas, Johann Roider, Hans Hoerauf
BACKGROUND: Ocular vascular occlusions following intraocular procedures are a rare complication. We report a case series of patients with retinal vascular occlusions or anterior ischemic optic neuropathy (AION) after anterior and posterior segment surgery and demonstrate possible risk factors. METHODS: Observational case series. RESULTS: In ten patients, vascular occlusions were observed within ten weeks after intraocular surgery: branch retinal arterial occlusion (BRAO) (n = 2), central retinal artery occlusion (CRAO) (n = 2), central retinal vein occlusion (CRVO) (n = 1), branch retinal vein occlusion (BRVO) (n = 1), anterior ischemic optic neuropathy (AION) (n = 3), and combined central artery and vein occlusion (n = 1)...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/28771491/atrial-fibrillation-in-retinal-vascular-occlusion-disease-and-non-arteritic-anterior-ischemic-optic-neuropathy
#2
Josep Callizo, Nicolas Feltgen, Antje Ammermann, Janina Ganser, Sebastian Bemme, Thomas Bertelmann, Sebastian Pfeiffer, Andre Duvinage, Klaus Gröschel, Hans Hoerauf, Rolf Wachter
BACKGROUND: Patients with retinal vascular occlusion disease have an increased risk for ischemic stroke and share some risk factors with cerebrovascular disease. The purpose of this study was to analyze the prevalence of atrial fibrillation (AF) in subjects with retinal vascular occlusive disease and anterior ischemic optic neuropathy and to compare these data to an ischemic stroke group. METHODS: Prospective, observational single-center trial. Subjects with retinal artery occlusion (RAO), retinal vein occlusion (RVO) and anterior ischemic optic neuropathy (AION) were included...
2017: PloS One
https://www.readbyqxmd.com/read/28759500/corticosteroid-therapy-in-nonarteritic-anterior-ischemic-optic-neuropathy-response
#3
Mark J Kupersmith, Neil R Miller, Leonard A Levin
No abstract text is available yet for this article.
September 2017: Journal of Neuro-ophthalmology: the Official Journal of the North American Neuro-Ophthalmology Society
https://www.readbyqxmd.com/read/28759499/corticosteroid-therapy-in-nonarteritic-anterior-ischemic-optic-neuropathy
#4
Sohan Singh Hayreh
No abstract text is available yet for this article.
September 2017: Journal of Neuro-ophthalmology: the Official Journal of the North American Neuro-Ophthalmology Society
https://www.readbyqxmd.com/read/28745999/trial-of-tocilizumab-in-giant-cell-arteritis
#5
RANDOMIZED CONTROLLED TRIAL
John H Stone, Katie Tuckwell, Sophie Dimonaco, Micki Klearman, Martin Aringer, Daniel Blockmans, Elisabeth Brouwer, Maria C Cid, Bhaskar Dasgupta, Juergen Rech, Carlo Salvarani, Georg Schett, Hendrik Schulze-Koops, Robert Spiera, Sebastian H Unizony, Neil Collinson
BACKGROUND: Giant-cell arteritis commonly relapses when glucocorticoids are tapered, and the prolonged use of glucocorticoids is associated with side effects. The effect of the interleukin-6 receptor alpha inhibitor tocilizumab on the rates of relapse during glucocorticoid tapering was studied in patients with giant-cell arteritis. METHODS: In this 1-year trial, we randomly assigned 251 patients, in a 2:1:1:1 ratio, to receive subcutaneous tocilizumab (at a dose of 162 mg) weekly or every other week, combined with a 26-week prednisone taper, or placebo combined with a prednisone taper over a period of either 26 weeks or 52 weeks...
July 27, 2017: New England Journal of Medicine
https://www.readbyqxmd.com/read/28742641/does-nocturnal-hypotension-play-a-causal-role-in-nonarteritic-anterior-ischemic-optic-neuropathy-response
#6
Anthony C Arnold
No abstract text is available yet for this article.
September 2017: Journal of Neuro-ophthalmology: the Official Journal of the North American Neuro-Ophthalmology Society
https://www.readbyqxmd.com/read/28742640/role-of-nocturnal-arterial-hypotension-in-nonarteritic-anterior-ischemic-optic-neuropathy
#7
Sohan Singh Hayreh
No abstract text is available yet for this article.
September 2017: Journal of Neuro-ophthalmology: the Official Journal of the North American Neuro-Ophthalmology Society
https://www.readbyqxmd.com/read/28733725/carotid-artery-intimal-medial-thickness-and-carotid-artery-plaques-in-hypertensive-patients-with-non-arteritic-anterior-ischaemic-optic-neuropathy
#8
Wenhui Zhu, Tingting Chen, Ling Jin, Haoyu Wang, Fengjuan Yao, Congyao Wang, Qi Wang, Nathan Congdon
PURPOSE: To assess the correlation of carotid artery intimal medial thickness (C-IMT) and carotid artery plaque score (CPS) of the common carotid artery with non-arteritic anterior ischemic optic neuropathy (NAION) in hypertensive patients. METHODS: This case-control study recruited 192 subjects. Forty-eight patients had NAION with systemic hypertension, 46 had hypertension without visual complaints, and 98 were normal controls. C-IMT and common carotid arterial plaque were measured by high-resolution vascular ultrasonography...
July 22, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/28716667/pupillometric-evaluation-of-the-melanopsin-containing-retinal-ganglion-cells-in-mitochondrial-and-non-mitochondrial-optic-neuropathies
#9
Shakoor Ba-Ali, Henrik Lund-Andersen
In recent years, chromatic pupillometry is used in humans to evaluate the activity of melanopsin expressing intrinsic photosensitive retinal ganglion cells (ipRGCs). Blue light is used to stimulate the ipRGCs and red light activates the rod/cone photoreceptors. The late re-dilation phase of pupillary light reflex is primarily driven by the ipRGCs. Optic neuropathies i.e. Leber hereditary optic neuropathy (LHON), autosomal dominant optic atrophy (ADOA), nonarteritic anterior ischemic optic neuropathy (NAION), glaucoma, optic neuritis and idiopathic intracranial hypertension (IIH) are among the diseases, which have been subject to pupillometric studies...
July 14, 2017: Mitochondrion
https://www.readbyqxmd.com/read/28687846/comparison-of-the-retinal-microvascular-density-between-open-angle-glaucoma-and-nonarteritic-anterior-ischemic-optic-neuropathy
#10
Chun-Hsiu Liu, Wei-Chi Wu, Ming-Hui Sun, Ling-Yuh Kao, Yung-Sung Lee, Henry Shen-Lih Chen
Purpose: To compare optical coherence tomography angiography (OCT-A) retinal vasculature measurements between nonarteritic anterior ischemic optic neuropathy (NAION) and open angle glaucoma (OAG) with altitudinal hemifield visual field defects. Methods: This retrospective cross-sectional study included 10 NAION eyes and 16 OAG eyes, both demonstrating hemifield visual field defects, and 27 normal eyes serving as controls. The peripapillary and macular OCT-A scans were acquired...
July 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28632028/the-effect-of-combined-systemic-erythropoietin-and-steroid-on-non-arteritic-anterior-ischemic-optic-neuropathy-a-prospective-study
#11
Mohammad Pakravan, Hamed Esfandiari, Kiana Hassanpour, Sarvnaz Razavi, Parastou Pakravan
BACKGROUND: To investigate the effect of combined intravenous (IV) erythropoietin (EPO) and corticosteroid as well as systemic steroid alone for the treatment of non-arteritic anterior ischemic optic neuropathy (NAION). METHODS: In this prospective interventional comparative case series, 113 consecutive patients diagnosed with recent onset (less than 14 days) NAION were included. Patients were categorized into three groups. 40 patients received systemic IV corticosteroid combined with recombinant human erythropoietin (rhEPO) (group 1), 43 patients received systemic corticosteroid alone (group 2), and 30 patients were enrolled as the control group (group 3)...
February 26, 2017: Current Eye Research
https://www.readbyqxmd.com/read/28619499/results-of-early-high-flow-bypass-and-trapping-for-ruptured-blood-blister-like-aneurysms-of-the-internal-carotid-artery
#12
Yuichiro Kikkawa, Toshiki Ikeda, Ririko Takeda, Hiroyuki Nakajima, Takeshi Ogura, Hidetoshi Ooigawa, Hiroki Kurita
OBJECTIVE: The aim of this study is to clarify the efficacy and safety of early surgery using trapping of the affected internal carotid artery (ICA) and high-flow bypass between second portion of the middle cerebral artery and cervical external carotid artery with radial artery graft for ruptured blood blister-like aneurysms (BBAs) arising from anterior wall of the ICA. METHODS: Medical chart of consecutive 16 patients (M:F=7:9, mean 59 years) with subarachnoid hemorrhage (WFNS grade I:2, II:5, III:2, IV:4, V:3) due to ruptured BBA surgically treated between July 2010 and October 2015 were retrospectively reviewed...
June 12, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28586576/non-arteritic-anterior-ischemic-optic-neuropathy-does-anticoagulation-help
#13
Akhunzada Muhammad Aftab, Mustafa Iqbal, Awais Rauf, Asif Ali
BACKGROUND: Non Arteritic Anterior Ischemic Optic Neuropathy (NAION) is the most common acute optic neuropathy in patients over 50 years of age. This study was conducted to determine the beneficial effects of anticoagulation with Heparin and Warfarin in patients with NAION presenting within 4 weeks of onset of symptoms. METHODS: A prospective, interventional, pilot study was conducted in Eye- A unit of Khyber Teaching Hospital from July 2010 onwards on patients with NAION presenting within 4 weeks of onset of symptoms...
October 2016: Journal of Ayub Medical College, Abbottabad: JAMC
https://www.readbyqxmd.com/read/28547004/ocular-arterial-occlusive-disorders-and-carotid-artery-disease
#14
Sohan Singh Hayreh, M Bridget Zimmerman
OBJECTIVE: To compare prevalence of carotid artery disease and its various types of lesions in different types of ocular arterial occlusive disorders. DESIGN: Cohort study. SUBJECTS: 614 consecutive patients (728 eyes) with ocular arterial occlusive disorders. METHODS: At first visit, all patients had a detailed ophthalmic and medical history, comprehensive ophthalmic evaluation, and carotid artery evaluation (by Doppler/angiography) on the side of ocular arterial occlusion, and echocardiography...
January 2017: Ophthalmology retina
https://www.readbyqxmd.com/read/28538037/dalfampridine-treatment-in-nonarteritic-anterior-ischemic-optic-neuropathy
#15
Mark L Moster, Robert C Sergott, Benjamin E Leiby
No abstract text is available yet for this article.
September 2017: Journal of Neuro-ophthalmology: the Official Journal of the North American Neuro-Ophthalmology Society
https://www.readbyqxmd.com/read/28538035/structure-function-analysis-of-nonarteritic-anterior-ischemic-optic-neuropathy-and-age-related-differences-in-outcome
#16
Ming-Hui Sun, Yaping Joyce Liao
BACKGROUND: The optic nerve head is vulnerable to ischemia leading to anterior ischemic optic neuropathy (AION), the most common acute optic neuropathy in those older than 50 years of age. METHODS: We performed a cross-sectional study of 55 nonarteritic anterior ischemic optic neuropathy (NAION) eyes in 34 patients to assess clinical outcome and perform structure-function correlations. RESULTS: The peak age of NAION onset was between 50 and 55 years...
September 2017: Journal of Neuro-ophthalmology: the Official Journal of the North American Neuro-Ophthalmology Society
https://www.readbyqxmd.com/read/28527029/critical-flicker-fusion-frequency-in-demyelinating-and-ischemic-optic-neuropathies
#17
Matthew T Young, Puneet S Braich, Scott R Haines
PURPOSE: Critical flicker fusion (CFF) frequency is a well-studied test for evaluating demyelinating optic neuritis (ON). Its use in evaluating other optic neuropathies is not well established. The purpose of this study was to compare CFF in ON and non-arteritic anterior ischemic optic neuropathy (NAION). METHODS: We performed a retrospective review to compare multiple variables for eyes with ON or NAION using two-sided T tests and Chi-square tests. A multivariate linear regression was performed for the dependent variable CFF...
May 19, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28524151/-etiopathogenesis-of-ocular-ischemic-syndrome
#18
D К Makhkamova
Ocular ischemic syndrome (OIS) is a collection of symptoms of carotid and ophthalmic artery disease of common genesis accompanied by ischemia of eyeball membranes. Specifically, the intraocular blood flow becomes impaired due to inflow reduction or arrest, while the venous outflow remains patent. Causes of OIS include arterial hypertension, atherosclerosis, diabetes, aortoarteritis and other vascular diseases. Clinical features depend on the extent, nature, and site of vascular involvement as well as the concurrent pathology...
2017: Vestnik Oftalmologii
https://www.readbyqxmd.com/read/28523333/giant-cell-arteritis-with-arteritic-anterior-ischemic-optic-neuropathy
#19
Horia Tudor Stanca, Elena Suvac, Mihnea Munteanu, Dragoş Cătălin Jianu, Andrei Gheorghe Marius Motoc, Gavril Cosmin Roşca, Ovidiu Boruga
Giant cell arteritis (GCA) is an inflammatory vasculitis of unknown etiology that mainly involves large and medium arteries, particularly the cranial branches of the aorta. GCA with consecutive arteritic-anterior ischemic optic neuropathy (A-AION) has rarely been diagnosed in Romania. Recently, we encountered an 83-year-old patient who presented with left eye visual impairment and corresponding optic disc diffusely swollen and pale. He also had typical manifestations of GCA, such as malaise, and temporal headache, and a highly elevated erythrocyte sedimentation rate and C-reactive protein level...
2017: Romanian Journal of Morphology and Embryology, Revue Roumaine de Morphologie et Embryologie
https://www.readbyqxmd.com/read/28513892/assessment-of-nonarteritic-anterior-ischemic-optic-neuropathy-with-intravoxel-incoherent-motion-diffusion-weighted-imaging-using-readout-segmented-echo-planar-imaging-parallel-imaging-and-2d-navigator-based-reacquisition
#20
Ping Lu, Yan Sha, Hailin Wan, Feng Wang, Guohong Tan, Wenlin Tang
PURPOSE: To determine the feasibility of intravoxel incoherent motion (IVIM) for characterizing perfusion properties and its potential diagnostic utility for nonarteritic anterior ischemic optic neuropathy (NAION). IVIM diffusion-weighted imaging is a promising technique that can measure perfusion and diffusion characteristics simultaneously in a noninvasive manner. MATERIALS AND METHODS: Orbital IVIM in a 3.0T scanner was performed on 33 patients with NAION and 15 controls using readout-segmented echo-planar imaging, parallel imaging, and 2D navigator-based reacquisition (RESOLVE-IVIM)...
May 17, 2017: Journal of Magnetic Resonance Imaging: JMRI
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