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https://www.readbyqxmd.com/read/28822921/the-relationship-of-physical-activity-to-high-density-lipoprotein-cholesterol-level-in-a-sample-of-community-dwelling-older-adults-from-amazonas-brazil
#1
Élvio R Gouveia, Andreas Ihle, Matthias Kliegel, Duarte L Freitas, Jefferson Jurema, Maria A Tinôco, Angeany Odim, Floramara T Machado, Bárbara R Muniz, António A Antunes, Rui T Ornelas, Bruna R Gouveia
OBJECTIVES: (1) To study the relation of physical activity (PA) to high-density lipoprotein cholesterol (HDL-C) and (2) to investigate if the strength of these associations holds after adjustments for sex, age, and other key correlates. METHODS: This study included 550 older adults from Amazonas. HDL-C was derived from fasting blood samples. PA at sport and leisure, smoking, alcohol consumption, and socioeconomic status (SES) were interviewed. Waist circumference (WACI) was assessed...
August 10, 2017: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/28822166/-clinical-observation-of-modified-da-chaihu-decoction-in-treating-essential-hypertension-with-anxiety
#2
Xiang-Dong Zhang, Wang-Qiang Cheng, Yong-Gang Wang, Zheng Zhang
To observe the clinical efficacy of modified Da Chaihu decoction in treating essential hypertension with anxiety, the randomized, controlled, clinical trial was performed in this study. One hundred and twenty-six hypertensive patients with anxiety meeting the inclusive criteria were randomized into the treatment group and the control group. All of the included patients in the above 2 groups were treated by amlodipine besylate tablets. Patients in the treatment group were given Chinese herbal medicine modified Da Chaihu decoction every day...
June 2017: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/28821856/smoking-obstructive-sleep-apnea-syndrome-and-their-combined-effects-on-metabolic-parameters-evidence-from-a-large-cross-sectional-study
#3
Huaming Zhu, Huajun Xu, Rui Chen, Suru Liu, Yunyan Xia, Yiqun Fu, Xinyi Li, Yingjun Qian, Jianyin Zou, Hongliang Yi, Jian Guan
Metabolic disorders have been separately associated with obstructive sleep apnea syndrome (OSAS) and smoking. However, no study has examined their interactions with metabolic parameters, including insulin resistance and dyslipidemia. To investigate whether the combination of OSAS and smoking results in an additive detriment in metabolic disorder parameters, we enrolled consecutive adult men during 2014-2015. Fasted blood samples were taken to determine glucose, insulin, and lipid levels. A questionnaire including an item on smoking pack-year exposure was administered, and the Epworth Sleepiness Scale and overnight polysomnography were performed...
August 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28821713/evaluating-the-causal-relation-of-apoa-iv-with-disease-related-traits-a-bidirectional-two-sample-mendelian-randomization-study
#4
Salome Mack, Stefan Coassin, Julien Vaucher, Florian Kronenberg, Claudia Lamina
Apolipoprotein A-IV (apoA-IV) has been observed to be associated with lipids, kidney function, adiposity- and diabetes-related parameters. To assess the causal relationship of apoA-IV with these phenotypes, we conducted bidirectional Mendelian randomization (MR) analyses using publicly available summary-level datasets from GWAS consortia on apoA-IV concentrations (n = 13,813), kidney function (estimated glomerular filtration rate (eGFR), n = 133,413), lipid traits (HDL cholesterol, LDL cholesterol, triglycerides, n = 188,577), adiposity-related traits (body-mass-index (n = 322,206), waist-hip-ratio (n = 210,088)) and fasting glucose (n = 133,010)...
August 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28821319/higher-dietary-acid-load-is-weakly-associated-with-higher-adiposity-measures-and-blood-pressure-in-japanese-adults-the-national-health-and-nutrition-survey
#5
Kentaro Murakami, M Barbara E Livingstone, Hitomi Okubo, Satoshi Sasaki
Epidemiologic evidence on the associations between dietary acid load and metabolic risk factors are limited and inconsistent. We investigated the hypothesis that dietary acid load is associated with adverse profiles of metabolic risk factors in Japanese adults. This cross-sectional study included 15 618 Japanese adults aged ≥20 years from the 2012 National Health and Nutrition Survey, Japan. Dietary acid load was characterized as potential renal acid load (PRAL) and net endogenous acid production (NEAP) based on information on nutrient intake, which was derived from a 1-day semi-weighed dietary record...
August 2017: Nutrition Research
https://www.readbyqxmd.com/read/28821087/in-vivo-antihyperlipidemic-and-antioxidant-activity-of-porphyran-in-hyperlipidemic-mice
#6
Xiaomei Wang, Weida Li, Li Xiao, Chundong Liu, Huimin Qi, Zhongshan Zhang
The hypolipidemic and antioxidant effects of porphyran from the red algae Porphyra haitanensis as a dietary supplement were evaluated in mice. The levels of serum TC, TG and LDL-C in MP group increased significantly (p<0.05 or p<0.01) by 28.5%, 29.4% and 33.5% compared with the model group. These significant rises were accompanied by significant declines of plasma HDL-C by 21.6% compared with the model group. In addition, the liver content of malondialdehyde significantly decreased, while the superoxide dismutase, catalase, glutathione peroxidase activities significantly increased...
October 15, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28816548/dietary-supplementation-with-virgin-coconut-oil-improves-lipid-profile-and-hepatic-antioxidant-status-and-has-potential-benefits-on-cardiovascular-risk-indices-in-normal-rats
#7
Ademola C Famurewa, Chima A Ekeleme-Egedigwe, Sophia C Nwali, Ngozi N Agbo, Joy N Obi, Goodness C Ezechukwu
Research findings that suggest beneficial health effects of dietary supplementation with virgin coconut oil (VCO) are limited in the published literature. This study investigated the in vivo effects of a 5-week VCO-supplemented diet on lipid profile, hepatic antioxidant status, hepatorenal function, and cardiovascular risk indices in normal rats. Rats were randomly divided into 3 groups: 1 control and 2 treatment groups (10% and 15% VCO-supplemented diets) for 5 weeks. Serum and homogenate samples were used to analyze lipid profile, hepatorenal function markers, hepatic activities of antioxidant enzymes, and malondialdehyde level...
August 17, 2017: Journal of Dietary Supplements
https://www.readbyqxmd.com/read/28815384/association-between-discordance-of-ldl-c-and-non-hdl-c-and-clinical-outcomes-in-patients-with-stent-implantation-from-the-fu-registry
#8
Michiyo Shiiba, Bo Zhang, Shin-Ichiro Miura, Amane Ike, Daisuke Nose, Takashi Kuwano, Satoshi Imaizumi, Makoto Sugihara, Atushi Iwata, Hiroaki Nishikawa, Akira Kawamura, Kazuyuki Shirai, Shin'ichiro Yasunaga, Keijiro Saku
It is not yet clear whether the discordance of low-density lipoprotein cholesterol (LDL-C) and non-high-density lipoprotein cholesterol (non-HDL-C) predicts the follow-up clinical outcome (major adverse cardiovascular events: MACEs) in patients with coronary stent implantation. Among 2015 patients with coronary stent implantation (Fukuoka University [FU]-Registry), excluding those with acute coronary syndrome or hemodialysis, we selected 801 patients who had undergone successful stent implantation with a follow-up until 18 months, and classified them into 3 groups according to baseline LDL-C and non-HDL-C levels [percentile(P)non-HDL-C more than (P)LDL-C, (P)non-HDL-C equal to (P)LDL-C, and (P)non-HDL-C less than (P) LDL-C]...
August 16, 2017: Heart and Vessels
https://www.readbyqxmd.com/read/28814963/effects-of-a-liquid-high-fat-meal-on-postprandial-lipid-metabolism-in-type-2-diabetic-patients-with-abdominal-obesity
#9
Feng Wang, Huixia Lu, Fukang Liu, Huizhen Cai, Zhixiu Song, Fei Guo, Yulan Xie, Guofang Shu, Guiju Sun
BACKGROUND: Postprandial lipemia and lipoprotein lipase (LPL) activity play crucial roles in the pathogenesis of accelerated atherosclerosis. This study aimed to evaluate the postprandial lipid metabolism after the ingestion of a liquid high-fat meal in type 2 diabetic patients with abdominal obesity, and determine if the PvuII polymorphisms of LPL influence their postprandial lipid responses. METHODS: Serum glucose, insulin, triglycerides (TG), total cholesterol (TC) and high density lipoprotein cholesterol (HDL-C) were measured in fasting and postprandial state at 0...
2017: Nutrition & Metabolism
https://www.readbyqxmd.com/read/28814962/circulating-zinc-%C3%AE-2-glycoprotein-levels-are-low-in-newly-diagnosed-patients-with-metabolic-syndrome-and-correlate-with-adiponectin
#10
Lu Lei, Kejia Li, Ling Li, Xia Fang, Tingting Zhou, Cheng Zhang, Yong Luo, Hua Liu, Xiaoqiang Li, Hongting Zheng, Lin Zhang, Gangyi Yang, Lin Gao
BACKGROUND: Zinc-α2-glycoprotein (ZAG) is a novel adipokine that reduces insulin resistance, protecting against type 2 diabetes. However, past studies have been contradictory. This cross-sectional study aims to investigate the association of circulating ZAG with metabolic syndrome (MetS) in middle-aged and older Chinese adults. METHODS: Four hundred eighty nine individuals (234 healthy controls and 255 MetS patients) were examined. All individuals were screened for MetS according to the diagnostic guidelines of the United States National Cholesterol Education Program (NCEP) Expert Panel Adult Treatment Panel (ATP) III criteria...
2017: Nutrition & Metabolism
https://www.readbyqxmd.com/read/28814835/efficacy-and-tolerability-of-two-different-formulations-of-atorvastatin-in-korean-patients-with-hypercholesterolemia-a-multicenter-prospective-randomized-clinical-trial
#11
Ju-Hee Lee, Sang-Hyun Kim, Dong-Ju Choi, Seung-Jea Tahk, Jung-Han Yoon, Si Wan Choi, Taek-Jong Hong, Hyo-Soo Kim
PURPOSE: This study was designed to compare the efficacy and tolerability of the generic formulation (Atorva(®)) and the reference formulation (Lipitor(®)) of atorvastatin, both at a dosage of 20 mg once daily. METHODS: This study was a prospective open-label, randomized controlled study. Hypercholesterolemic patients who had not achieved low-density lipoprotein (LDL) cholesterol goals according to the National Cholesterol Education Program Adult Treatment Panel III (NCEP-ATP III) guideline were randomized to generic formulation or reference formulation of atorvastatin...
2017: Drug Design, Development and Therapy
https://www.readbyqxmd.com/read/28814394/dynamics-of-intrapericardial-and-extrapericardial-fat-tissues-during-long-term-dietary-induced-moderate-weight-loss
#12
Gal Tsaban, Arik Wolak, Hila Avni-Hassid, Yftach Gepner, Ilan Shelef, Yaakov Henkin, Dan Schwarzfuchs, Noa Cohen, Nitzan Bril, Michal Rein, Dana Serfaty, Shira Kenigsbuch, Lilac Tene, Hila Zelicha, Anat Yaskolka-Meir, Oded Komy, Avital Bilitzky, Yoash Chassidim, Uta Ceglarek, Michael Stumvoll, Matthias Blüher, Joachim Thiery, Dror Dicker, Assaf Rudich, Meir J Stampfer, Iris Shai
Background: In view of evidence linking pericardial fat accumulation with increased cardiovascular disease risk, strategies to reduce its burden are needed. Data comparing the effects of specific long-term dietary interventions on pericardial fat tissue mobilization are sparse.Objective: We sought to evaluate intrapericardial-fat (IPF) and extrapericardial-fat (EPF) changes during weight-loss interventions by different dietary regimens.Design: During 18 mo of a randomized controlled trial, we compared a Mediterranean/low-carbohydrate (MED/LC) diet plus 28 g walnuts/d with a calorically equal low-fat (LF) diet among randomly assigned participants with moderate abdominal obesity...
August 16, 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28811852/the-cluster-of-abnormalities-related-to-metabolic-syndrome-is-associated-with-reduced-glomerular-filtration-rate-and-raised-albuminuria-in-patients-with-type-2-diabetes-mellitus
#13
Miki Kurata, Akiko Takenouchi, Ayaka Tsuboi, Satomi Minato, Mika Takeuchi, Kaori Kitaoka, Keisuke Fukuo, Tsutomu Kazumi
BACKGROUND: As association of metabolic syndrome (MS) with chronic kidney disease (CKD) has not been extensively studied in patients with type 2 diabetes, we addressed these issues. METHODS: Intrapersonal means of 12 measurements of waist circumference, blood pressure and high-density lipoprotein (HDL) cholesterol and those of six measurements of fasting triglycerides during 12 months were calculated in a cohort of 168 previously reported Japanese patients with type 2 diabetes...
September 2017: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/28811778/effects-of-blood-lipid-stability-on-progression-of-carotid-atherosclerosis
#14
Yu Ding, Bo Li, Feng Tian, Shanshan Zhou, Yundai Chen
OBJECTIVE: To evaluate the effects of blood lipid stability on progression of carotid atherosclerosis. METHODS: A total of 416 patients who had physical examination in our hospital annually from January 2010 to December 2015 were selected and divided into a progression group (n=216) and a non-progression group (n=200) according to the intima-media thickness measured by carotid ultrasound. The levels of lipid-related parameters within five years were retrospectively analyzed to calculate the smoothness index (SI = x±/s)...
May 2017: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/28811698/effect-of-tulsi-ocimum-sanctum-linn-supplementation-on-metabolic-parameters-and-liver-enzymes-in-young-overweight-and-obese-subjects
#15
Swayamjeet Satapathy, Namrata Das, Debapriya Bandyopadhyay, Sushil Chandra Mahapatra, Dip Sundar Sahu, Mruthyumjayarao Meda
Ocimum sanctum Linn. (also known as Tulsi) is a sacred Indian plant, the beneficial role of which, in obesity and diabetes is described traditionally. This is a randomized, parallel group, open label pilot study to investigate the effect of O. sanctum on metabolic and biochemical parameters in thirty overweight/obese subjects, divided into two groups A and B. Group A (n = 16) received one 250 mg capsule of Tulsi (O. sanctum) extract twice daily in empty stomach for 8 weeks and group B (n = 14) received no intervention...
July 2017: Indian Journal of Clinical Biochemistry: IJCB
https://www.readbyqxmd.com/read/28810853/acute-effects-of-reducing-sitting-time-in-adolescents-a-randomized-cross-over-study
#16
Anisse Penning, Anthony D Okely, Stewart G Trost, Jo Salmon, Dylan P Cliff, Marijka Batterham, Steven Howard, Anne-Maree Parrish
BACKGROUND: Levels of sitting among adolescents are high, especially during the school day. The acute cognitive and health consequences associated with prolonged sitting are poorly understood in adolescents. This randomized crossover design study examined the acute effects of a simulated school day with reduced sitting or usual sitting on adolescents' cognitive function and cardiometabolic biomarkers. METHODS: Eighteen healthy school aged adolescents were recruited from the community to the study (11 males; 7 females; mean age [SD] = 13...
August 15, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28810840/the-association-between-tuberculosis-and-the-development-of-insulin-resistance-in-adults-with-pulmonary-tuberculosis-in-the-western-sub-district-of-the-cape-metropole-region-south-africa-a-combined-cross-sectional-cohort-study
#17
Lauren Philips, Janicke Visser, Daan Nel, Renée Blaauw
BACKGROUND: The existence of a bi-directional relationship between tuberculosis (TB) and insulin resistance (IR)/diabetes has been alluded to in literature. Although diabetes has been linked to increased tuberculosis risk, the relationship between tuberculosis as a causative factor for IR remains unclear. The study aimed to determine if an association existed between tuberculosis and IR development in adults with newly diagnosed pulmonary tuberculosis at baseline. It was additionally aimed to document changes in IR status during TB follow-up periods...
August 15, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28808791/consumption-of-extra-virgin-olive-oil-improves-body-composition-and-blood-pressure-in-women-with-excess-body-fat-a-randomized-double-blinded-placebo-controlled-clinical-trial
#18
Flávia Galvão Cândido, Flávia Xavier Valente, Laís Emilia da Silva, Olívia Gonçalves Leão Coelho, Maria do Carmo Gouveia Peluzio, Rita de Cássia Gonçalves Alfenas
PURPOSE: Despite the fact that extra virgin olive oil (EVOO) is widely used in obese individuals to treat cardiovascular diseases, the role of EVOO on weight/fat reduction remains unclear. We investigated the effects of energy-restricted diet containing EVOO on body composition and metabolic disruptions related to obesity. METHODS: This is a randomized, double-blinded, placebo-controlled clinical trial in which 41 adult women with excess body fat (mean ± SD 27...
August 14, 2017: European Journal of Nutrition
https://www.readbyqxmd.com/read/28808297/secretory-phospholipase-a2-modified-hdl-rapidly-and-potently-suppresses-platelet-activation
#19
Sanja Curcic, Michael Holzer, Lisa Pasterk, Eva Knuplez, Thomas O Eichmann, Saša Frank, Robert Zimmermann, Rudolf Schicho, Akos Heinemann, Gunther Marsche
Levels of secretory phospholipases A2 (sPLA2) highly increase under acute and chronic inflammatory conditions. sPLA2 is mainly associated with high-density lipoproteins (HDL) and generates bioactive lysophospholipids implicated in acute and chronic inflammatory processes. Unexpectedly, pharmacological inhibition of sPLA2 in patients with acute coronary syndrome was associated with an increased risk of myocardial infarction and stroke. Given that platelets are key players in thrombosis and inflammation, we hypothesized that sPLA2-induced hydrolysis of HDL-associated phospholipids (sPLA2-HDL) generates modified HDL particles that affect platelet function...
August 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28808236/decreased-high-density-lipoprotein-cholesterol-is-an-independent-predictor-for-persistent-organ-failure-pancreatic-necrosis-and-mortality-in-acute-pancreatitis
#20
Yushun Zhang, Feng Guo, Shoukang Li, Feiyang Wang, Zibo Meng, Jingyuan Zhao, Zhiqiang Liu, Bo Wang, Ping Fan, Chunyou Wang, Heshui Wu
High density lipoprotein cholesterol (HDL-C) has been reported as a significant indicator of systemic inflammation. The association underlying HDL-C and persistent organ failure (POF), pancreatic necrosis (PNec) and mortality in acute pancreatitis (AP) has not been evaluated. From 2007 to 2016, consecutive AP patients with admission lipid profiles assessment were included in this study. The association of HDL-C value and other lipids with outcomes was explored with Cox proportional regression models, which were adjusted for confounding factors...
August 14, 2017: Scientific Reports
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