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Hdl p

AndréOliveira Werneck, Danilo Rodrigues Pereira da Silva, Rômulo Araújo Fernandes, EnioRicardoVaz Ronque, Manuel J Coelho-E-Silva, Edilson Serpeloni Cyrino
Sports practice during childhood can influence health indicators in later ages through direct and indirect pathways. Thus, this study aimed to test direct and indirect pathways to the association between sports practice in childhood and metabolic risk in adolescence, adopting physical activity, adiposity, and cardiorespiratory fitness at adolescence as potential mediators. This cross-sectional study with retrospective information was conducted with 991 adolescents (579 girls, 412 boys) aged 10 to 16 y. Sports activity was self-reported in childhood (retrospective data) and physical activity evaluated in adolescence through questionnaires...
June 21, 2018: International Journal of Sports Medicine
James P Corsetti, Tanzy M Love, Charles E Sparks, Stephan J L Bakker, Robin P F Dullaart
OBJECTIVE: Familial dysbetalipoproteinemia (FD) or Type III hyperlipoproteinemia is closely associated with the ε2ε2 genotype of the common APOE polymorphism although not all ε2 homozygotes develop FD indicating that additional factors play a role including insulin resistance (IR). The current study was undertaken to explore relationships and influences among factors, especially IR, that might elucidate FD progression pathways. METHODS: Bayesian network (BN) modeling, a probabilistic graphical exploratory data analysis tool that portrays relationships and influences among variables as simple diagrams, was applied to 52 e2e2 subjects...
June 18, 2018: Clinical Biochemistry
Séphora Louyse Silva Aquino, Aline Tuane Oliveira da Cunha, Hermilla Torres Pereira, Erika Paula Silva Freitas, Ana Paula Trussardi Fayh, Josivan Gomes Lima, Severina Carla Vieira Cunha Lima, Karine Cavalcanti Maurício Sena-Evangelista, Lucia Fátima Campos Pedrosa
Background: The risk of metabolic syndrome can be influenced by inadequate vitamin D levels, and exposure to sunlight is the main external source of vitamin D. The present study assessed the influence of environmental, biological, and nutritional factors in relation to seasonal 25-hydroxyvitamin D (25OHD) concentration in individuals with metabolic syndrome. Methods: This cross-sectional study enrolled 180 individuals with metabolic syndrome aged between 18 and 80 years...
2018: Diabetology & Metabolic Syndrome
Lukasz Szternel, Magdalena Krintus, Katarzyna Bergmann, Tadeusz Derezinski, Grazyna Sypniewska
OBJECTIVE: Despite the common use of non-fasting measurements for lipid profile in children it remains unclear as to the extent non-fasting conditions have on laboratory results of lipids measurements. We aimed to assess the impact of non-fasting lipid profile on the occurrence of dyslipidemia in children. MATERIALS AND METHODS: Basic lipid profile including: total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C) and triglycerides (TG), as well as small, dense-LDL-C (sd-LDL-C), apolipoprotein AI (ApoAI), apolipoprotein B (ApoB) and lipoprotein(a) [Lp(a)], were measured in 289 presumably healthy children aged 9-11 in both fasting and non-fasting condition...
2018: PloS One
Susan Darroudi, Maryam Saberi-Karimian, Maryam Tayefi, Soheil Arekhi, Ali Motamedzadeh Torghabeh, Seyed Mohammad Reza Seyedzadeh Sani, Mohsen Moohebati, Alireza Heidari-Bakavoli, Mahmoud Ebrahimi, Mahmoud Reza Azarpajouh, Mohammad Safarian, Gordon A Ferns, Habibollah Esmaeili, Mohammad Reza Parizadeh, Naghme Mokhber, Adeleh Mahdizadeh, Ali Asghar Mahmoudi, Amir Hossein Sahebkar, Majid Ghayour-Mobarhan
BACKGROUND: Combination of dyslipidemic phenotypes, including elevated plasma levels of low-density lipoprotein cholesterol (LDL-C), elevated plasma triglycerides (TG), and decreased low-density lipoprotein cholesterol (HDL-C) concentrations, is important because of the association of individual phenotypes with increased risk of cardiovascular disease (CVD). We investigated the prevalence of combined dyslipidemias and their effects on CVD risk in an Iranian large population. METHOD: A total of 9847 individuals were recruited as part of the Mashhad Stroke and Heart Atherosclerotic Disorders (MASHAD) cohort study...
June 21, 2018: Journal of Clinical Laboratory Analysis
Ning-Chuan Li, Xia-Lian Yin, Xiu-Xia Wei, Wei Lu, Shi-Wen Shen, Lang Xiao, Yu-Long Hu
OBJECTIVES: To investigate the interventional effects of 16-week aerobic exercises on the elderly's arteriosclerosis and its mechanism. METHODS: Twenty-seven elderly people with the average age of 62. 70 ±3. 26 joined a 16-week square dance/taijiquan exercise program that conducted 60 minutes each time, six times per week. Arterial stiffness and its related indexes such as systolic pressure(SBP), diastolic pressure(DBP), left brachial-ankle pulse wave velocity (L-baPWV), right brachial-ankle pulse wave velocity(R-baPWV), left ankle brachial index (L-ABI), right ankle brachial index(R-ABI), serum triglyceride(TG), total cholesterol(TC), high density lipoprotein cholesterol(HDL-c), low density lipoprotein cholesterol(LDL-c), superoxide dismutase(SOD), malondialdehyde(MDA) and glutathione peroxidase (GSH-Px) were detected at 3 time points including before exercise program, by the end of exercise for 8 weeks and 16 weeks...
February 8, 2018: Chinese Journal of Applied Physiology
Yong-Qiu Yan, Guan-Hai Dai, Shi-Ping Jiang, Yu Lu, Ying-Peng Tong, Ping Wang
OBJECTIVES: To investigate the effect of two kinds of fermented food, noni juice and natto, on blood glucose and lipids in induced diabetic mice. METHODS: Female (ICR) mice were induced into diabetes by an injection of alloxan (55 mg/kg, i. v.). After 72 hours, those mice whose fasting blood glucose levels were over 12.00 mmol/L and urine sugar was strongly positive (+ + +) were regarded as diabetical model and were randomly divided into three groups ( n =10):diabetical model (DM) group, noni juice (NJ) group and natto (NT) group...
February 8, 2018: Chinese Journal of Applied Physiology
Sheng-Chang Yang, Ling-Ling Chen, Tian Fu, Wen-Ya Li, En-Sheng Ji
OBJECTIVE: To explore the effects of hydrogen on liver injury in chronic intermittent hypoxia rats and the related oxidative stress mechanism. METHODS: Twenty-four male adult SD rats were randomly divided into 3 groups( n =8):the normoxia group (Norm), the chronic intermittent hypoxia group (CIH), the chronic intermittent hypoxia and hydrogen group (H2 + CIH). Rats in Norm group were exposed in air, those in the other 2 groups suffered from chronic intermittent hypoxia conditions for 5 weeks...
January 8, 2018: Chinese Journal of Applied Physiology
Tao Liu, Shi Bai, Rong-Chao Zhang
OBJECTIVE: To investigate the effect of Health Qigong Baduanjin on the related indexes of obese middle aged women with diabetes and to provide new ideas for the intervention treatment of diabetes. METHODS: A total of 40 middle-aged female obese diabetic patients were randomly divided into the control group and the exercise group( n =20), the age was(57.2±5.4) years old. Fitness training group performed eight new Baduanjin exercises for 24 weeks of intervention, the control group did not exercise, body weight, waist circumference, body mass index (BMI), waist hip ratio (WHR), fasting blood glucose (FPG), glycosylated hemoglobin (HbAlc), triglyceride(TG), total cholesterol (TC), low density lipoprotein (LDL), high density lipoprotein (HDL) levels and serum retinol binding protein 4(RBP4) index were observed in the two groups...
January 8, 2018: Chinese Journal of Applied Physiology
Chunhua Deng, Zhichao Zhang, Hongjun Li, Peng Bai, Xian Cao, Adrian Sandra Dobs
OBJECTIVE: To investigate associations between cardiovascular disease risk factors, including fasting glucose, cholesterol, high density lipoprotein cholesterol (HDL-c), LDL-c, blood pressure, body mass index (BMI), C-peptide, creatinine kinase, smoking, alcohol use, physical activity, C-reactive protein as well as homocysteine levels and cardiovascular events. METHODS: Data from 1545 men aged ≥40 years, with testosterone deficiency (TD) (<300 ng/dL) and non-TD (≥300 ng/dL) which were extracted from the National Health and Nutrition Examination Survey database 2011-2012 and analyzed...
June 20, 2018: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
Jan-Erik Guelker, Alexander Bufe, Christian Blockhaus, Knut Kroeger, Thomas Rock, Ibrahim Akin, Michael Behnes, Kambis Mashayekhi
BACKGROUND: The plasma-derived atherogenic index (AIP) is associated with an increasing risk for cardiovascular diseases. Whether an increased AIP may predict the complexity of percutaneous coronary intervention (PCI) of chronic total occlusion (CTO), according to available research, has never been investigated before. METHODS: 317 patients were included prospectively and treated with PCI for at least one CTO between 2012 and 2017. High-density lipoprotein cholesterol (HDL-C) and triglycerides (TG) plasma levels were measured 24 h before PCI...
June 20, 2018: Cardiology Journal
M S Santana, K P Nascimento, P A Lotufo, I M Benseãor, F C Meotti
Allantoin is the main product of uric acid oxidation and was found to be augmented in atherosclerotic plaque in human autopsy and in animal models of atherosclerosis. Uric acid is abundant in human plasma and is prone to oxidation in inflammatory conditions such as atherosclerosis. In this study, we found a significant increase in plasma uric acid (P=0.002) and allantoin (P=0.025) in participants of the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil) that presented common carotid intima-media thickness (c-IMT) within the 75th percentile (c-IMT≥P75)...
2018: Brazilian Journal of Medical and Biological Research, Revista Brasileira de Pesquisas Médicas e Biológicas
Kashinath Dixit, Dinesh Venkata Kamath, Krishnaraju Venkata Alluri, Barbara A Davis
AIMS: LI85008F is a novel, proprietary herbal blend containing extracts of Moringa oleifera and Murraya koeingii leaves plus extract of Curcuma longa root. Weight loss efficacy of LI85008F was first demonstrated in obese adults and has now been re-evaluated in healthy overweight adults via a 16-week randomized, double-blind, placebo-controlled clinical study. MATERIAL & METHODS: One hundred and forty overweight participants (Body mass index 27 to 29.9 kg/m2 , 29...
June 19, 2018: Diabetes, Obesity & Metabolism
Mohammed Nader Salama, Ahmed Abulfotooh Eid, Alaa Hatem, Ahmed Kamal Swidan
OBJECTIVES: Determination of the potential effect of metabolic syndrome (MetS) on erectile function in Egyptian men and description of the sociodemographic characteristics of these men. MATERIALS AND METHODS: A cohort of 615 patients presenting to urology department aged between 30 and 75 years were prospectively assessed and divided into two groups. Group I (n = 325) diagnosed with MetS and mean age of 56.07 ± 8.51 years. Group II (n = 290) subjects with no MetS and mean age 54...
June 19, 2018: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
Megan Lloyd, Dawn A Skelton, Gillian E Mead, Brian Williams, Frederike van Wijck
INTRODUCTION: Physical fitness training after stroke is recommended in guidelines across the world, but evidence pertains mainly to ambulatory stroke survivors. Nonambulatory stroke survivors (FAC score ≤2) are at increased risk of recurrent stroke due to limited physical activity. This systematic review aimed to synthesize evidence regarding case fatality, effects, experiences, and feasibility of fitness training for nonambulatory stroke survivors. METHODS: Eight major databases were searched for any type of study design...
June 19, 2018: Brain and Behavior
Taryn J Smith, Laura Tripkovic, Hanne Hauger, Camilla T Damsgaard, Christian Mølgaard, Susan A Lanham-New, Kathryn H Hart
Background: Epidemiologic studies have supported inverse associations between low serum 25-hydroxyvitamin D [25(OH)D] and cardiometabolic risk markers, but few randomized trials have investigated the effect of vitamin D supplementation on these markers in adolescents. Objective: The objective of this study was to investigate the effect of winter-time cholecalciferol (vitamin D3) supplementation on cardiometabolic risk markers in white, healthy 14- to 18-y-old adolescents in the UK (51°N) as part of the ODIN Project...
June 15, 2018: Journal of Nutrition
Annemarie M den Harder, Pim A de Jong, Mark C H de Groot, Jelmer M Wolterink, Ricardo P J Budde, Ivana Iŝgum, Wouter W van Solinge, Maarten J Ten Berg, Esther Lutgens, Wouter B Veldhuis, Saskia Haitjema, Imo E Hoefer, Tim Leiner
BACKGROUND AND AIMS: We aimed to improve the understanding of potential associations between commonly available hematological biomarkers and the coronary artery calcification (CAC) score, which may help unravel the pathophysiology of coronary calcifications and subclinical coronary artery disease. METHODS: A cross-sectional study was performed within the Utrecht Patient Oriented Database (UPOD). Patients with suspected or known coronary artery disease who underwent CT CAC scoring as well as standard hematology analysis that was part of routine clinical care (within 3 months of CT acquisition) were included...
June 12, 2018: Atherosclerosis
Li-Juan Sun, Gu-Feng Xu, Min Lv, Hao Zhou, He-Feng Huang, Qiong Luo
BACKGROUND: In clinical practice, abnormal biochemical changes often occur in women who eventually develop preeclampsia (PE). The study aims to investigate whether maternal serum biochemical markers in the early third trimester can predict PE and neonatal birth weight. STUDY DESIGN: A retrospective case-control study was performed on 287 women who subsequently developed PE (mild = 139; severe = 148) and 143 healthy women. Fasting venous blood samples of all gravidas were drawn for routine biochemical markers screening in the early third trimester (28...
June 19, 2018: Journal of Women's Health
Tatiana Sequeira Gross, Shiho Naito, Niklas Neumann, Johannes Petersen, Thomas Kuntze, Hermann Reichenspurner, Yskert von Kodolitsch, Evaldas Girdauskas
Background: Studies have demonstrated that statin therapy decreases the growth rate of abdominal aneurysms. However, the effect of statin therapy on the proximal aortic disease has not been sufficiently elucidated. Aim: We aimed to analyze the association between statin treatment and the severity of proximal aortopathy in patients with aortic valve disease. Design: Cross-sectional study. Methods: We prospectively identified 458 patients who were referred for aortic valve surgery from 2008 to 2014...
June 18, 2018: QJM: Monthly Journal of the Association of Physicians
Hanne Hauger, Christian Mølgaard, Charlotte Mortensen, Christian Ritz, Hanne Frøkiær, Taryn J Smith, Kathryn Hart, Susan A Lanham-New, Camilla T Damsgaard
Background: Low serum 25-hydroxyvitamin D [25(OH)D] has been associated with unfavorable cardiometabolic risk profiles in many observational studies in children, but very few randomized controlled trials have investigated this. Objective: We explored the effect of winter-time cholecalciferol (vitamin D3) supplementation on cardiometabolic risk markers in young, white, 4- to 8-y-old healthy Danish children (55°N) as part of the pan-European ODIN project. Methods: In the ODIN Junior double-blind, placebo-controlled, dose-response trial, 119 children (mean ± SD age: 6...
June 15, 2018: Journal of Nutrition
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