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https://www.readbyqxmd.com/read/28704244/implementation-of-a-standardized-transfusion-protocol-for-cardiac-patients-treated-with-venoarterial-extracorporeal-membrane-oxygenation-is-associated-with-decreased-blood-component-utilization-and-may-improve-clinical-outcome
#1
Christine M Cahill, Neil Blumberg, Amy E Schmidt, Peter A Knight, Amber L Melvin, Howard T Massey, Joseph M Delehanty, Seth B Zebrak, Majed A Refaai
BACKGROUND: Extracorporeal membrane oxygenation supplies oxygenated blood to the body supporting the heart and lungs. Survival rates of 20% to 50% are reported among patients receiving ECMO for cardiac arrest, severe cardiogenic shock, or failure to wean from cardiopulmonary bypass following cardiac surgery. Bleeding is one of the most common complications in ECMO patients due to coagulopathy, systemic anticoagulation, and the presence of large bore cannulas at systemic pressure. Absence of a standardized transfusion protocol in this population leads to inconsistent transfusion practices...
July 10, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28587644/current-and-future-perspectives-on-the-management-of-polypharmacy
#2
Mariam Molokhia, Azeem Majeed
BACKGROUND: Because of ageing populations, the growth in the number of people with multi-morbidity and greater compliance with disease-specific guidelines, polypharmacy is becoming increasingly common. Although the correct drug treatment in patients with complex medical problems can improve clinical outcomes, quality of life and life expectancy, polypharmacy is also associated with an increased risk of adverse drug events, some severe enough to result in hospital admission and even death...
June 6, 2017: BMC Family Practice
https://www.readbyqxmd.com/read/28536820/crescent-fractures-of-the-pelvis-treated-by-open-reduction-and-internal-fixation-a-critique-of-day-s-guidelines
#3
K Venugopal Menon, S S Suresh, Sivaprasad Kalyanasundaram, Jacob Varughese
INTRODUCTION: Day's classification and treatment guidelines are considered the gold standard in crescent fractures of the pelvis. The objective of this study was to retrospectively evaluate 10 surgically treated crescent fractures of the pelvis in the context of Day's recommendations. METHODS: This is a retrospective cohort study. Ten consecutive cases of crescent fractures that were treated surgically at a level 1 trauma center formed the cohort. Six were operated anteriorly, three posteriorly and one percutaneously...
May 23, 2017: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
https://www.readbyqxmd.com/read/28454756/pregnancy-of-unknown-location-a-survey-based-evaluation-of-when-and-why-physicians-intervene
#4
Majed S Faden, Suhaib Khayat, Richard N Brown
INTRODUCTION: Management of pregnancies of unknown location (PUL) is a complex challenging clinical situation with possibilities for pitfalls. Obstetricians and gynaecologists of varied levels of training and experience from Canada and the Nordic countries were questioned about their approach when faced with PUL. METHOD: A 13-item web-based questionnaire was used to evaluate physicians' behaviors by surveying their management of a PUL encountered at different levels of human chorionic gonadotropin (hCG)...
May 2017: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
https://www.readbyqxmd.com/read/28004062/optimal-timing-of-vitamin-k-antagonist-resumption-after-upper-gastrointestinal-bleeding-a-risk-modelling-analysis
#5
Ammar Majeed, Niklas Wallvik, Joakim Eriksson, Jonas Höijer, Matteo Bottai, Margareta Holmström, Sam Schulman
The optimal timing of vitamin K antagonists (VKAs) resumption after an upper gastrointestinal (GI) bleeding, in patients with continued indication for oral anticoagulation, is uncertain. We included consecutive cases of VKA-associated upper GI bleeding from three hospitals retrospectively. Data on the bleeding location, timing of VKA resumption, recurrent GI bleeding and thromboembolic events were collected. A model was constructed to evaluate the 'total risk', based on the sum of the cumulative rates of recurrent GI bleeding and thromboembolic events, depending on the timing of VKA resumption...
February 28, 2017: Thrombosis and Haemostasis
https://www.readbyqxmd.com/read/27686301/breast-cancer-treatment-in-high-risk-elderly-patients-a-challenging-situation-and-difficult-decisions
#6
Razia Bano, Amina Iqbal Khan, Waleed Zafar, Akif Abbas Zaidi, Adil Asif Zaidi, Mohammad Zulrqurnain Chaudhry, Huma Majeed Khan
OBJECTIVE: To assess whether high-risk elderly patients with aggressive tumour biology can be offered standard treatment despite having multiple comorbid conditions. METHODS: This retrospective study was conducted at Shaukat Khanum Memorial Cancer Hospital and Research Centre, Lahore, Pakistan, and comprised data of breast cancer patients aged 65 years or above treated between 2006 and 2012,. Data was collected regarding patients' demographics, baseline clinical characteristics, comorbidities, treatment and outcomes...
October 2016: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/27681262/slowing-the-tide-of-alcohol-use-disorders
#7
Hassan Chamsi-Pasha, Majed Chamsi-Pasha, Mohammed Ali Albar
Alcohol use disorders (AUDs)-a spectrum including at-risk drinking, alcohol abuse, dependence, and addiction-is a highly prevalent problem worldwide with a substantial economic impact. The toll of alcohol on individual health and healthcare systems is devastating. Alcohol is estimated to be the fifth leading risk factor for global disability-adjusted life years. Tackling the problem of AUD requires a comprehensive strategy that includes solid action on price, availability, and marketing of alcohol. Restricting or banning alcohol advertising may reduce exposure to the risk posed by alcohol at the individual and general population level...
September 28, 2016: Journal of Religion and Health
https://www.readbyqxmd.com/read/27222366/how-would-a-decision-to-leave-the-european-union-affect-medical-research-and-health-in-the-united-kingdom
#8
EDITORIAL
Azeem Majeed, Anna Hansell, Sonia Saxena, Christopher Millett, Helen Ward, Matthew Harris, Benedict Hayhoe, Josip Car, Graham Easton, Christl A Donnelly, Robert Perneczky, Marjo-Riitta Jarvelin, Majid Ezzati, Salman Rawaf, Paolo Vineis, Neil Ferguson, Elio Riboli
No abstract text is available yet for this article.
May 24, 2016: Journal of the Royal Society of Medicine
https://www.readbyqxmd.com/read/26976655/pragmatic-message-to-junior-doctors
#9
Hassan Chamsi-Pasha, Majed Chamsi-Pasha, Mohammed Ali Albar
Although several studies described the experience of doctors in their first postgraduate years, few shed the light on the ethical issues encountered by them. These doctors face a broad range of 'everyday' ethical challenges, from breach of confidentiality to truth-telling or improper informed consent. The daily ethical issues faced by junior doctors are not as dramatic as the major issues learned at medical school. Junior doctors have to make the best ethical decisions within the time limits available. Undergraduate medical ethics curricula should give priority to the real-life issues that doctors will face in their first years of practice...
July 2016: Postgraduate Medical Journal
https://www.readbyqxmd.com/read/26916686/quality-of-care-in-university-hospitals-in-saudi-arabia-a-systematic-review
#10
REVIEW
Mohammed Aljuaid, Fahmida Mannan, Zain Chaudhry, Salman Rawaf, Azeem Majeed
OBJECTIVES: To identify the key issues, problems, barriers and challenges particularly in relation to the quality of care in university hospitals in the Kingdom of Saudi Arabia (KSA), and to provide recommendations for improvement. METHODS: A systematic search was carried out using five electronic databases, for articles published between January 2004 and January 2015. We included studies conducted in university hospitals in KSA that focused on the quality of healthcare...
February 25, 2016: BMJ Open
https://www.readbyqxmd.com/read/26351410/-partners-rather-than-just-providers%C3%A2-a-qualitative-study-on-health-care-professionals-views-on-implementation-of-multidisciplinary-group-meetings-in-the-north-west-london-integrated-care-pilot
#11
Angelos P Kassianos, Agnieszka Ignatowicz, Geva Greenfield, Azeem Majeed, Josip Car, Yannis Pappas
INTRODUCTION: Multidisciplinary group meetings are one of the key drivers of facilitating integrated care. Health care professionals attending such groups have a key role in the success of these discussions and hence, in the forming of multi-professional integrated care. The study aimed to explore the professionals' experiences and views of participating and implementing the groups in integrated care context. METHODS: A qualitative study including 25 semi-structured interviews with professionals participating in the Northwest London Integrated Care Pilot analysed using thematic content analysis...
July 2015: International Journal of Integrated Care
https://www.readbyqxmd.com/read/26241930/automated-negotiation-in-environmental-resource-management-review-and-assessment
#12
REVIEW
Faezeh Eshragh, Majeed Pooyandeh, Danielle J Marceau
Negotiation is an integral part of our daily life and plays an important role in resolving conflicts and facilitating human interactions. Automated negotiation, which aims at capturing the human negotiation process using artificial intelligence and machine learning techniques, is well-established in e-commerce, but its application in environmental resource management remains limited. This is due to the inherent uncertainties and complexity of environmental issues, along with the diversity of stakeholders' perspectives when dealing with these issues...
October 1, 2015: Journal of Environmental Management
https://www.readbyqxmd.com/read/25985502/nursing-educational-motivation-and-barriers-inventory
#13
Majed Alamri, Nancy Sharts-Hopko
BACKGROUND AND PURPOSE: The major purposes of the study are revision of the Nursing Educational Motivation and Barriers Inventory (NEMBI) and translation of it into Arabic. METHODS: NEMBI was translated into Arabic, then back-translated to ensure the accuracy of the translation. The translation and back-translation of NEMBI were accurate and identical. A panel of experts provided content validation. Reliability was evaluated in a pilot test. For the larger study, 158 Saudi nurses completed the NEMBI...
2015: Journal of Nursing Measurement
https://www.readbyqxmd.com/read/25772278/emergency-pelvic-stabilization-in-patients-with-pelvic-posttraumatic-instability
#14
Dan V Poenaru, Mircea Popescu, Bogdan Anglitoiu, Iulian Popa, Diana Andrei, Florin Birsasteanu
INTRODUCTION: Unstable pelvic ring disruptions have been associated with high rates of morbidity. Accurate reduction with fixation diminishes pain, permits early patient mobility, and allows the pelvic ring to improve functional outcome. MATERIAL AND METHODS: This was a retrospective study, whereby 30 polytrauma hospitalized patients were included, with unstable pelvic lesions stabilized with an external fixator as a mean of temporary or definitive fixation. Data collected for these sample were: age, sex, cause of trauma, type of pelvic lesion, associated lesions (ISS score), pelvic stabilization methods, and functional outcome...
May 2015: International Orthopaedics
https://www.readbyqxmd.com/read/25457241/acceptability-of-the-decision-support-for-safer-surgery-tool
#15
Wynne E Norton, Patrick W Hosokawa, William G Henderson, Eric T Volckmann, Joyce Pell, Majed G Tomeh, Robert E Glasgow, Sung-Joon Min, Leigh A Neumayer, Mary T Hawn
BACKGROUND: We examined providers' perceptions of the Decision Support for Safer Surgery (DS3) tool, which provided preoperative patient-level risk estimates of postoperative adverse events. METHODS: The DS3 tool was evaluated at 2 academic medical centers. During the validation study, surgeons provided usefulness ratings of the DS3 tool for each patient before surgery. At the end of the study, providers' perceptions of the DS3 tool were assessed via questionnaire...
June 2015: American Journal of Surgery
https://www.readbyqxmd.com/read/25160152/chronoquery-visual-modelling-of-temporal-queries-for-real-time-decision-support
#16
Raphael W Majeed, Mark R Stöhr, Thorsten Brenner, Rainer Röhrig
Clinical decision support systems are an important aspect of medical informatics. The increasing amount of available patient data requires physicians to rely on information technology for research and during their day by day work. In intensive care medicine, fast actions are especially important. One major step towards enabling direct interaction of medical staff with patient data was the development of clinical data repositories with easy query frontends. While clinical data repositories can be extended for the use of real-time data, the corresponding query frontends do not support the time concepts necessary for real-time queries and decision support...
2014: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/24987321/assessing-patients-experience-of-integrated-care-a-survey-of-patient-views-in-the-north-west-london-integrated-care-pilot
#17
Nikolaos Mastellos, Laura Gunn, Matthew Harris, Azeem Majeed, Josip Car, Yannis Pappas
INTRODUCTION: Despite the importance of continuity of care and patient engagement, few studies have captured patients' views on integrated care. This study assesses patient experience in the Integrated Care Pilot in North West London with the aim to help clinicians and policymakers understand patients' acceptability of integrated care and design future initiatives. METHODS: A survey was developed, validated and distributed to 2029 randomly selected practice patients identified as having a care plan...
April 2014: International Journal of Integrated Care
https://www.readbyqxmd.com/read/24421348/reasons-for-attending-an-urban-urgent-care-centre-with-minor-illness-a-questionnaire-study
#18
C Amiel, B Williams, F Ramzan, S Islam, T Ladbrooke, A Majeed, S Gnani
INTRODUCTION: The demand for urgent care is increasing, and the pressure on emergency departments is of significant concern. General practitioner (GP)-led urgent care centres are a new model of care developed to divert patients to more appropriate primary care environments. This study explores why patients with minor illness choose to attend an urban urgent care centre for their healthcare needs. METHODS: A self-completed questionnaire among patients aged 18 years or over (N=649) who were triaged with a 'minor illness' on arrival to an urgent care centre, colocated with an emergency department in London...
October 2014: Emergency Medicine Journal: EMJ
https://www.readbyqxmd.com/read/24284794/dynamic-adhesion-of-eryptotic-erythrocytes-to-immobilized-platelets-via-platelet-phosphatidylserine-receptors
#19
Britta Walker, Syeda T Towhid, Evi Schmid, Sascha M Hoffmann, Majed Abed, Patrick Münzer, Sebastian Vogel, Felix Neis, Sara Brucker, Meinrad Gawaz, Oliver Borst, Florian Lang
Glucose depletion of erythrocytes triggers suicidal erythrocyte death or eryptosis, which leads to cell membrane scrambling with phosphatidylserine exposure at the cell surface. Eryptotic erythrocytes adhere to endothelial cells by a mechanism involving phosphatidylserine at the erythrocyte surface and CXCL16 as well as CD36 at the endothelial cell membrane. Nothing has hitherto been known about an interaction between eryptotic erythrocytes and platelets, the decisive cells in primary hemostasis and major players in thrombotic vascular occlusion...
February 1, 2014: American Journal of Physiology. Cell Physiology
https://www.readbyqxmd.com/read/23978619/a-spatial-web-agent-based-model-to-support-stakeholders-negotiation-regarding-land-development
#20
Majeed Pooyandeh, Danielle J Marceau
Decision making in land management can be greatly enhanced if the perspectives of concerned stakeholders are taken into consideration. This often implies negotiation in order to reach an agreement based on the examination of multiple alternatives. This paper describes a spatial web/agent-based modeling system that was developed to support the negotiation process of stakeholders regarding land development in southern Alberta, Canada. This system integrates a fuzzy analytic hierarchy procedure within an agent-based model in an interactive visualization environment provided through a web interface to facilitate the learning and negotiation of the stakeholders...
November 15, 2013: Journal of Environmental Management
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