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Nocturia

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https://www.readbyqxmd.com/read/29782887/endoscopic-injection-of-low-dose-triamcinolone-a-simple-minimally-invasive-and-effective-therapy-for-interstitial-cystitis-with-hunner-lesions
#1
Michael G Funaro, Alexandra N King, Joel N H Stern, Robert M Moldwin, Sonia Bahlani
OBJECTIVES: To investigate the efficacy of low dose triamcinolone injection for effectiveness and durability in interstitial cystitis/bladder pain syndrome (IC/BPS) patients with Hunner Lesions (HL). MATERIALS & METHODS: Clinical data from patients with HL who underwent endoscopic submucosal injection of triamcinolone were reviewed: Demographics, pre/post operative pain and nocturia scores, and long-term clinical outcomes were assessed. Duration of response was estimated by time to repeat procedure...
May 18, 2018: Urology
https://www.readbyqxmd.com/read/29774671/is-it-worth-treating-non-bothering-nocturia-results-of-a-multicenter-prospective-observational-study
#2
Kwangsung Park, Hyoung Keun Park, Sae Woong Kim, Dae Yul Yang, Jong Kwan Park, Hyun Jun Park, Ki Hak Moon, Du Geon Moon, Kweon Sik Min, Hwancheol Son, Sung Won Lee, Jae Seog Hyun, Woo Suk Choi, Sang Kuk Yang
PURPOSE: The purpose of this study was to evaluate the efficacy of treatment in patients with non-bothering nocturia. MATERIALS AND METHODS: In this prospective multicenter study, patients who visited hospitals for treatment of voiding symptoms were enrolled. Inclusion criteria were: 1) men >45 years, and 2) nocturia ≥2 confirmed by a three-day voiding diary. Subjects were divided into non-bothering and bothering groups based on International Consultation on Incontinence Questionnaire Nocturia (ICIQ-N) question 2b...
May 17, 2018: World Journal of Men's Health
https://www.readbyqxmd.com/read/29773418/-the-obstructive-sleep-apnoea-syndrome-is-not-only-bad-for-the-heart
#3
J Rajaoarifetra, A Palot, D Tissier Ducamp, C Tummino, M Gouitaa, P Chanez
Obstructive sleep apnoea (OSA) is common in the general population, particularly in the elderly. This syndrome is frequently responsible for severe cardiovascular complications. However, the indications for its treatment in the elderly remain controversial. We report the case of a 79-year-old man with severe, undiagnosed OSA who inhaled his fixed dental bridge during sleep. The inhaled foreign body came to rest in the lumen of the left main stem bronchus. The association of obesity with a body mass index of 30kg/m2 , snoring with breathing pauses reported by his partner, nocturia, morning headache and an Epworth score of 11 led to polysomnography which confirmed OSA with an apnoea/hypopnoea index of 53 per hour...
May 14, 2018: Revue des Maladies Respiratoires
https://www.readbyqxmd.com/read/29769252/frequency-of-non-motor-symptoms-in-parkinson-s-disease-presenting-to-tertiary-care-centre-in-pakistan-an-observational-cross-sectional-study
#4
Shahid Mukhtar, Rashid Imran, Mohsin Zaheer, Huma Tariq
OBJECTIVE: To determine the frequency of non-motor symptoms (NMS) in patients of Parkinson's disease (PD) presenting to a movement disorder clinic at a tertiary care centre in Pakistan, and how frequency of NMS is different in male and female patients. STUDY DESIGN: Observational, cross-sectional study. SETTING: Tertiary care centre. PARTICIPANTS: Out of 102 patients, 85 were included. Inclusion criteria were patients with PD diagnosed according to the UK Parkinson's Disease Society Brain Bank Clinical Diagnostic Criteria, age ≥18 years, able to give consent and have no difficulty in answering questions...
May 16, 2018: BMJ Open
https://www.readbyqxmd.com/read/29767479/nocturia-is-more-bothersome-than-daytime-luts-results-from-an-observational-real-life-practice-database-including-8659-european-and-american-luts-patients
#5
Karel Everaert, Peter Anderson, Robert Wood, Fredrik L Andersson, Tove Holm-Larsen
PURPOSE: Lower urinary tract symptoms (LUTS) encompass several diagnoses, including overactive bladder (OAB) and benign prostatic hyperplasia (BPH). Nocturia is a standalone symptom, but also included in OAB and BPH. Current discussion addresses whether the overlap of the diagnoses is too broad, leading to misdiagnosis. This study explored the differences in level, causes and consequences for patients with a diagnosis of daytime LUTS compared with a diagnosis of nocturia, and discussed whether people are being treated for the symptoms that truly bother them the most...
May 16, 2018: International Journal of Clinical Practice
https://www.readbyqxmd.com/read/29761019/assessment-of-sleep-quality-using-cardiopulmonary-coupling-analysis-in-patients-with-parkinson-s-disease
#6
Lindi Chen, Chunyan Liu, Zhinan Ye, Binda Wang, Songbin He
Objectives: To assess the sleep quality of patients with Parkinson's disease (PD) and evaluate the effect of cardiopulmonary coupling (CPC) analysis on sleep quality and its correlation with subjective complaints in patients with PD. Methods: Our study included 42 patients with PD and 30 healthy controls. CPC analysis and the Pittsburgh Sleep Quality Index (PSQI) were used to evaluate the sleep quality of subjects. Results: High-frequency coupling (HFC) and sleep efficiency were significantly lower in the PD than in the control group, whereas very low-frequency coupling (VLFC) and sleep latency were significantly higher in the PD than in the control group...
May 2018: Brain and Behavior
https://www.readbyqxmd.com/read/29752971/metabolomic-analysis-of-overactive-bladder-in-male-patients-identification-of-potential-metabolite-biomarkers
#7
Hiroshi Shimura, Takahiko Mitsui, Satoru Kira, Tatsuya Ihara, Norifumi Sawada, Hiroshi Nakagomi, Tatsuya Miyamoto, Sachiko Tsuchiya, Mie Kanda, Masayuki Takeda
OBJECTIVES: To identify metabolites that are associated with an overactive bladder (OAB) using metabolomics. PATIENTS AND METHODS: A total of 58 males without apparent neurological disease completed 24-hr bladder diaries of their micturition behavior and International Prostate Symptom Score (IPSS) for the assessment of micturition behavior and lower urinary tract symptoms. Urgency was defined as an IPSS urgency score of ≥2 (OAB group), and patients with IPSS urgency scores of ≤1 belonged to the control group...
May 9, 2018: Urology
https://www.readbyqxmd.com/read/29747213/treatment-of-non-neurogenic-overactive-bladder-with-onabotulinumtoxina-systematic-review-and-meta-analysis-of-prospective-randomized-placebo-controlled-clinical-trials
#8
Raquel Martins Arruda, Claudia Cristina Takano, Manoel João Batista Castelo Girão, Jorge Milhem Haddad, Gabriel Francisco Aleixo, Rodrigo Aquino Castro
We performed a systematic review and meta-analysis of randomized placebo-controlled trials that studied non-neurogenic overactive bladder patients who were treated with 100 units of onabotulinumtoxinA or placebo. The primary purpose of our study was to evaluate the clinical effectiveness with regard to urinary urgency, urinary frequency, nocturia, and incontinence episodes. Our secondary purpose consisted of evaluating the adverse effects. Our initial search yielded 532 entries. Of these, seven studies met all the inclusion criteria (prospective, randomized, placebo-controlled studies, ≥ 3 points on the Jadad scale) and were selected for analysis...
April 2018: Revista Brasileira de Ginecologia e Obstetrícia
https://www.readbyqxmd.com/read/29745932/analysis-of-tolerance-and-security-of-chemo-hyperthermia-with-mitomycin-c-for-the-treatment-of-non-muscle-invasive-bladder-cancer
#9
Juan León-Mata, José Luis Domínguez, Joan Palou Redorta, Daniel Sousa González, María Alvarez Casal, Alejandro Sousa Escandón, Eva Piñeiro Vázquez
OBJECTIVES: The treatment of non muscle invasive bladder cancer (NMIBC) continues to be a challenge. Hyperthermia (HT) combined with intravesical chemotherapy is used to enhance the effects of chemotherapy. METHODS: A review of the publications was carried out to synthesize the adverse effects (AE) reported by the use of chemohyperthermia (QHT) with Mitomycin-C (MMC). The most relevant data are exposed for each of the devices currently used in the QHT. RESULTS: SYNERGO®: The dropout rate varied between 3-40%, and the AE rate is up to 88%...
May 2018: Archivos Españoles de Urología
https://www.readbyqxmd.com/read/29744473/the-prevalence-of-lower-urinary-tract-symptoms-in-population-aged-40-years-or-over-in-south-korea
#10
Tag Keun Yoo, Kyu-Sung Lee, Budiwan Sumarsono, Sung-Tae Kim, Hyun-Jung Kim, Hyun-Cheol Lee, Sun-Hwa Kim
Purpose: Lower urinary tract symptoms (LUTS) can be distressing and socially isolating, and the economic impact can be substantial. Further data to characterize the epidemiology and effects of LUTS in South Korea would be beneficial. Materials and Methods: In an international, internet-based survey, the prevalence and impact of LUTS was evaluated in adults aged ≥40 years. Questions related to International Continence Society (ICS) symptom definitions and the bother associated with each symptom...
May 2018: Investigative and Clinical Urology
https://www.readbyqxmd.com/read/29735367/sleep-disturbance-has-a-higher-impact-on-general-and-mental-quality-of-life-reduction-than-nocturia-results-from-the-community-health-survey-in-japan
#11
Koichi Kido, Shingo Hatakeyama, Atsushi Imai, Hayato Yamamoto, Yuki Tobisawa, Tohru Yoneyama, Takahiro Yoneyama, Yasuhiro Hashimoto, Takuya Koie, Shigeyuki Nakaji, Chikara Ohyama
BACKGROUND: Nocturia has been reported to be associated with sleep disturbance. However, whether nocturia or sleep disturbance has a more negative influence on the quality of life (QOL) of individuals remains unclear. OBJECTIVE: To compare the impact of nocturia and sleep disturbance on QOL. DESIGN, SETTING, AND PARTICIPANTS: This was a cross-sectional study including 3992 adults who participated in the Iwaki Health Promotion Project between 2011 and 2015 in Hirosaki, Japan...
May 4, 2018: European Urology Focus
https://www.readbyqxmd.com/read/29732215/a-ligamentous-explanation-for-overactive-bladder-symptoms-as-defined-by-international-continence-society-in-the-female
#12
REVIEW
Peter Petros
The International Continence Society (ICS) committee has defined overactive bladder (OAB) as "a syndrome characterized by symptoms of urgency, with or without urgency incontinence, usually with increased daytime frequency and nocturia (increased night time urination). The term OAB can only be used if there is no proven infection or other obvious pathology". Though the ICS gives no anatomical basis for OAB, it is suggested that the cause is from the detrusor itself. In this review, urodynamic evidence is presented that OAB in the female may be a prematurely activated but normal micturition reflex, as predicted by the Integral Theory...
2018: Central European Journal of Urology
https://www.readbyqxmd.com/read/29718792/a-younger-man-with-localized-prostate-cancer-asks-which-type-of-radiation-is-right-for-me
#13
Justin E Bekelman
The Oncology Grand Rounds series is designed to place original reports published in the Journal into clinical context. A case presentation is followed by a description of diagnostic and management challenges, a review of the relevant literature, and a summary of the authors' suggested management approaches. The goal of this series is to help readers better understand how to apply the results of key studies, including those published in Journal of Clinical Oncology, to patients seen in their own clinical practice...
May 2, 2018: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/29709423/basic-and-clinical-aspects-of-antimuscarinic-agents-used-to-treat-overactive-bladder
#14
REVIEW
Shizuo Yamada, Yoshihiko Ito, Saori Nishijima, Katsumi Kadekawa, Kimio Sugaya
Antimuscarinic agents are now widely used as the pharmacological therapy for overactive bladder (OAB) because neuronal (parasympathetic nerve) and non-neuronal acetylcholine play a significant role for the bladder function. In this review, we will highlight basic and clinical aspects of eight antimuscarinic agents (oxybutynin, propiverine, tolterodine, solifenacin, darifenacin, trospium, imidafenacin, and fesoterodine) clinically used to treat urinary dysfunction in patients with OAB. The basic pharmacological characteristics of these eight antimuscarinic agents include muscarinic receptor subtype selectivity, functional bladder selectivity, and muscarinic receptor binding in the bladder and other tissues...
April 27, 2018: Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/29703021/rare-foreign-body-in-bladder-a-case-report
#15
Yubing Li, Yunqiu Gao, Xiangdong Chen, Shaobo Jiang
RATIONALE: The bladder is the most common site of foreign bodies in the urinary tract. Presenting complaints in patients with a foreign body are urinary retention, dysuria, frequent urination, decreased urine volume, nocturia, hematuria, painful erection, as well as pain in the urethra and pelvis. PATIENT CONCERNS: A 50-year-old married male presented with complaints of severe lower abdominal pain and dysuria. DIAGNOSES: A plain radiograph of the pelvis showed a metallic dense foreign body that was composed of many small magnetic balls in the pelvic region...
April 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29698965/lack-of-change-in-the-adaptation-ability-of-the-bladder-for-the-urine-production-rate-in-aged-men-with-nocturia
#16
Satoru Kira, Takahiko Mitsui, Tatsuya Miyamoto, Tatsuya Ihara, Hiroshi Nakagomi, Norifumi Sawada, Masayuki Takeda
INTRODUCTION: To investigate the association between bladder capacity and the urine production rate in aged men with or without nocturia using a frequency volume chart (FVC). MATERIALS AND METHODS: One-hundred and thirty-eight men aged 65-80 years were enrolled. After the International Prostate Symptom Score (IPSS) and 3 consecutive days FVC were evaluated, men were divided into 2 groups: Nocturia group, with any total IPSS, and ≥1.5 micturition on average at night; and Control group, with total IPSS < 8 and < 1...
April 26, 2018: Urologia Internationalis
https://www.readbyqxmd.com/read/29696555/desmopressin-induced-severe-hyponatremia-with-central-pontine-myelinolysis-a-case-report
#17
Tanzib Hossain, Marya Ghazipura, Vineet Reddy, Pedro J Rivera, Vikramjit Mukherjee
Desmopressin, a synthetic vasopressin analog, is used to treat central diabetes insipidus, hemostatic disorders such as von Willebrand's disease, and nocturnal enuresis. We present the case of a 69-year-old man who developed severe hyponatremia during treatment with intranasal desmopressin at 10 µg twice daily for chronic polyuria and nocturia thought to be due to central diabetes insipidus. After 5 months of therapy, the patient noticed progressive fatigue, anorexia, dizziness, weakness, light-headedness, decreased concentration, and new-onset falls...
April 25, 2018: Drug Safety—Case Reports
https://www.readbyqxmd.com/read/29694707/efficacy-and-safety-of-a-hexanic-extract-of-serenoa-repens-permixon-%C3%A2-for-the-treatment-of-lower-urinary-tract-symptoms-associated-with-benign-prostatic-hyperplasia-luts-bph-systematic-review-and-meta-analysis-of-randomized-controlled-trials-and-observational
#18
Remigio Vela-Navarrete, Antonio Alcaraz, Alfredo Rodríguez-Antolín, Bernardino Miñana López, Jesús M Fernández-Gómez, Javier C Angulo, David Castro Díaz, Javier Romero-Otero, Francisco J Brenes, Joaquín Carballido, José M Molero García, Antonio Fernández-Pro Ledesma, José Manuel Cózar Olmos, José Manasanch Dalmau, Isaac Subirana Cachinero, Michael Herdman, Vincenzo Ficarra
OBJECTIVES: To comprehensively evaluate the efficacy and safety of the hexanic extract of Serenoa repens (HESr, Permixon), at a dose of 320 mg daily, as monotherapy for the treatment of LUTS/BPH. MATERIALS AND METHODS: Systematic review and meta-analysis of randomized and observational studies in patients with LUTS/BPH identified through searches in Medline, Web of Knowledge [ISI], Scopus, the Cochrane Library, and bibliographic references up to March 2017. Articles studying S...
April 25, 2018: BJU International
https://www.readbyqxmd.com/read/29692690/overactive-bladder-syndrome-evaluation-and-management
#19
REVIEW
Elad Leron, Adi Y Weintraub, Salvatore A Mastrolia, Polina Schwarzman
Overactive bladder (OAB) syndrome is a chronic medical condition which has a major influence on the quality of life in a significant amount of the population. OAB affects performance of daily activities and has an estimated prevalence of 16.5%. Many sufferers do not seek medical help. Moreover, many family physicians and even gynecologists are not familiar with this issue. Usually patients suffer from OAB in advanced age. Nocturia is reported as the most bothersome symptom in the elderly population. The aim of our review was to discuss all aspects of this challenging disorder and suggest tools for assessment and management strategies...
March 2018: Current Urology
https://www.readbyqxmd.com/read/29683042/factors-affecting-continuation-of-clean-intermittent-catheterisation-in-people-with-multiple-sclerosis-results-of-the-cosmos-mixed-methods-study
#20
Doreen McClurg, Carol Bugge, Andrew Elders, Tasneem Irshad, Suzanne Hagen, Katherine N Moore, Brian Buckley, Mandy Fader
BACKGROUND: Clean intermittent catheterisation (CIC) is often recommended for people with multiple sclerosis (MS). OBJECTIVE: To determine the variables that affect continuation or discontinuation of the use of CIC. METHODS: A three-part mixed-method study (prospective longitudinal cohort ( n = 56), longitudinal qualitative interviews ( n = 20) and retrospective survey ( n = 456)) was undertaken, which identified the variables that influenced CIC continuation/discontinuation...
April 1, 2018: Multiple Sclerosis: Clinical and Laboratory Research
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