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https://www.readbyqxmd.com/read/29237500/impact-of-chronic-pseudomonas-aeruginosa-infection-on-health-related-quality-of-life-in-mycobacterium-avium-complex-lung-disease
#1
Hirofumi Kamata, Takanori Asakura, Shoji Suzuki, Ho Namkoong, Kazuma Yagi, Yohei Funatsu, Satoshi Okamori, Shunsuke Uno, Yoshifumi Uwamino, Hiroshi Fujiwara, Tomoyasu Nishimura, Makoto Ishii, Tomoko Betsuyaku, Naoki Hasegawa
BACKGROUND: In bronchiectasis patients, chronic Pseudomonas aeruginosa (PA) infection has been associated with worse health-related quality of life (HRQL), but little is known about Mycobacterium avium complex lung disease (MACLD) patients in this context. This study aimed to evaluate HRQL and investigate the impact of chronic PA infection in MACLD patients. METHODS: This cross-sectional study was conducted using the Registry of Prospective Cohort Study including MACLD patients...
December 13, 2017: BMC Pulmonary Medicine
https://www.readbyqxmd.com/read/29233054/pretreatment-serum-lactate-dehydrogenase-as-a-prognostic-indicator-for-oral-cavity-squamous-cell-carcinoma
#2
Yukinori Takenaka, Ryohei Oya, Kengo Aoki, Hiroko Hamaguchi, Kazuya Takemura, Masayuki Nozawa, Takahiro Kitamura, Yoshifumi Yamamoto, Atsuhiko Uno
OBJECTIVES: To examine whether lactate dehydrogenase (LDH) can predict the prognosis of oral cavity squamous cell carcinoma (OSCC) and to determine the optimal cut-off values for LDH. METHODS: This retrospective study included 184 patients with OSCC, treated with surgery between 2006 and 2014. The association between LDH and T, N classification was investigated using the Mann-Whitney test. Cut-off values for LDH were determined with a recursive partitioning analysis (RPA)...
December 12, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/29228622/comparison-between-liver-resection-and-liver-transplantation-on-outcomes-in-patients-with-solitary-hepatocellular-carcinoma-meeting-unos-criteria-a-population-based-study-of-the-seer-database
#3
Anli Yang, Weiqiang Ju, Xiaopeng Yuan, Ming Han, Xiaoping Wang, Zhiyong Guo, Xiaoli Wei, Dongping Wang, Xiaofeng Zhu, Linwei Wu, Xiaoshun He
Liver resection (LR) and liver transplantation (LT) are potential curative treatment methods for early hepatocellular carcinoma (HCC). However, it is controversial which treatment is more beneficial to patients with solitary HCC meeting the United Network for Organ Sharing (UNOS) criteria (single lesion, diameter≤50mm, no vascular invasion, no extrahepatic metastasis). We retrieved patients with solitary HCC meeting UNOS criteria diagnosed between 2004-2013 from the Surveillance Epidemiology and End Results (SEER) database...
November 14, 2017: Oncotarget
https://www.readbyqxmd.com/read/29227039/mid-term-results-of-bariatric-surgery-in-morbidly-obese-japanese-patients-with-slow-progressive-autoimmune-diabetes
#4
Kohei Uno, Yosuke Seki, Kazunori Kasama, Kotaro Wakamatsu, Kenkichi Hashimoto, Akiko Umezawa, Katsuhiko Yanaga, Yoshimochi Kurokawa
INTRODUCTION: Bariatric surgery is recognized as an effective treatment for type 2 diabetes mellitus, but data on its efficacy for type 1 diabetes mellitus, especially slowly progressive insulin-dependent diabetes mellitus, are limited. METHODS: We investigated five Japanese patients with slowly progressive insulin-dependent diabetes mellitus who underwent bariatric surgery at our center. RESULTS: Five morbidly obese glutamic acid decarboxylase antibody-positive diabetic patients underwent two different types of bariatric surgery...
December 11, 2017: Asian Journal of Endoscopic Surgery
https://www.readbyqxmd.com/read/29226563/fatal-cardiac-arrest-in-pediatric-heart-transplant-recipients-query-of-the-unos-database
#5
Robert W Loar, Susan W Denfield, Shaine A Morris, Hari P Tunuguntla, Antonio G Cabrera, Jack F Price, Wei Zhang, Katherine Hosek, Jeffrey J Kim, William J Dreyer, Aamir Jeewa
The incidence of death by CA after PHTx is unknown. We aimed to determine the incidence and factors for fatal CA after PHTx, and whether a PM affects survival. Retrospective cohort study utilizing the United Network of Organ Sharing registry of patients transplanted ≤18 years. Multivariable analyses in hazard-function domain and Kaplan-Meier analyses were performed for an outcome of death due to CA. There were 7719 PHTx patients queried. CA was the reported cause of death in 11%. Age ≥13 years at time of transplant, presence of a PM, and depressed EF were identified as significant factors for fatal CA...
December 10, 2017: Pediatric Transplantation
https://www.readbyqxmd.com/read/29222916/transplanting-hcv-positive-livers-into-hcv-negative-patients-with-preemptive-antiviral-treatment-a-modeling-study
#6
Jagpreet Chhatwal, Sumeyye Samur, Emily D Bethea, Turgay Ayer, Fasiha Kanwal, Chin Hur, Mark S Roberts, Norah Terrault, Raymond T Chung
Under current guidelines hepatitis C virus (HCV)-positive livers are not transplanted into HCV-negative recipients because of adverse post-transplant outcomes associated with allograft HCV infection. However, HCV can now be cured post liver transplant (LT) using direct-acting antivirals (DAAs) with >90% success; therefore, HCV-negative patients on the liver transplant (LT) waiting list may benefit from accepting HCV-positive organs with preemptive treatment. Our objective was to evaluate if and in which HCV-negative patients the potential benefit of accepting an HCV-positive (i...
December 9, 2017: Hepatology: Official Journal of the American Association for the Study of Liver Diseases
https://www.readbyqxmd.com/read/29219495/evidence-for-isospin-violation-and-measurement-of-cp-asymmetries-in-b%C3%A2-k-892-%C3%AE
#7
T Horiguchi, A Ishikawa, H Yamamoto, I Adachi, H Aihara, S Al Said, D M Asner, V Aulchenko, T Aushev, R Ayad, V Babu, I Badhrees, A M Bakich, V Bansal, P Behera, V Bhardwaj, B Bhuyan, J Biswal, A Bobrov, G Bonvicini, A Bozek, M Bračko, T E Browder, D Červenkov, V Chekelian, A Chen, B G Cheon, K Chilikin, K Cho, Y Choi, D Cinabro, T Czank, N Dash, S Di Carlo, Z Doležal, Z Drásal, D Dutta, S Eidelman, D Epifanov, H Farhat, J E Fast, T Ferber, B G Fulsom, V Gaur, N Gabyshev, A Garmash, M Gelb, R Gillard, P Goldenzweig, B Golob, Y Guan, E Guido, J Haba, T Hara, K Hayasaka, H Hayashii, M T Hedges, T Higuchi, S Hirose, W-S Hou, T Iijima, K Inami, G Inguglia, R Itoh, Y Iwasaki, W W Jacobs, I Jaegle, H B Jeon, S Jia, Y Jin, D Joffe, K K Joo, T Julius, K H Kang, T Kawasaki, D Y Kim, J B Kim, K T Kim, M J Kim, S H Kim, Y J Kim, K Kinoshita, P Kodyš, S Korpar, D Kotchetkov, P Križan, P Krokovny, T Kuhr, R Kulasiri, R Kumar, T Kumita, A Kuzmin, Y-J Kwon, J S Lange, C H Li, L Li, L Li Gioi, J Libby, D Liventsev, M Lubej, T Luo, M Masuda, T Matsuda, D Matvienko, M Merola, K Miyabayashi, H Miyata, R Mizuk, G B Mohanty, S Mohanty, H K Moon, T Mori, R Mussa, E Nakano, M Nakao, T Nanut, K J Nath, Z Natkaniec, M Nayak, N K Nisar, S Nishida, S Ogawa, S Okuno, H Ono, P Pakhlov, G Pakhlova, B Pal, S Pardi, C-S Park, H Park, S Paul, T K Pedlar, R Pestotnik, L E Piilonen, K Prasanth, C Pulvermacher, J Rauch, A Rostomyan, Y Sakai, S Sandilya, L Santelj, V Savinov, O Schneider, G Schnell, C Schwanda, A J Schwartz, Y Seino, K Senyo, I S Seong, M E Sevior, V Shebalin, C P Shen, T-A Shibata, J-G Shiu, F Simon, A Sokolov, E Solovieva, M Starič, J F Strube, K Sumisawa, T Sumiyoshi, M Takizawa, U Tamponi, K Tanida, F Tenchini, K Trabelsi, M Uchida, T Uglov, Y Unno, S Uno, P Urquijo, Y Ushiroda, Y Usov, C Van Hulse, G Varner, A Vinokurova, V Vorobyev, A Vossen, C H Wang, M-Z Wang, P Wang, Y Watanabe, S Watanuki, T Weber, E Widmann, E Won, Y Yamashita, H Ye, Z P Zhang, V Zhilich, V Zhukova, V Zhulanov, A Zupanc
We report the first evidence for isospin violation in B→K^{*}γ and the first measurement of the difference of CP asymmetries between B^{+}→K^{*+}γ and B^{0}→K^{*0}γ. This analysis is based on the data sample containing 772×10^{6}BB[over ¯] pairs that was collected with the Belle detector at the KEKB energy-asymmetric e^{+}e^{-} collider. We find evidence for the isospin violation with a significance of 3.1σ, Δ_{0+}=[+6.2±1.5(stat)±0.6(syst)±1.2(f_{+-}/f_{00})]%, where the third uncertainty is due to the uncertainty on the fraction of B^{+}B^{-} to B^{0}B[over ¯]^{0} production in ϒ(4S) decays...
November 10, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/29219447/search-for-cp-violation-and-measurement-of-the-branching-fraction-in-the-decay-d-0-%C3%A2-k_-s-0-k_-s-0
#8
N Dash, S Bahinipati, V Bhardwaj, K Trabelsi, I Adachi, H Aihara, S Al Said, D M Asner, V Aulchenko, T Aushev, R Ayad, V Babu, I Badhrees, A M Bakich, V Bansal, E Barberio, B Bhuyan, J Biswal, A Bobrov, A Bondar, G Bonvicini, A Bozek, M Bračko, F Breibeck, T E Browder, D Červenkov, M-C Chang, V Chekelian, A Chen, B G Cheon, K Chilikin, K Cho, Y Choi, D Cinabro, S Di Carlo, Z Doležal, Z Drásal, D Dutta, S Eidelman, D Epifanov, H Farhat, J E Fast, T Ferber, B G Fulsom, V Gaur, N Gabyshev, A Garmash, R Gillard, P Goldenzweig, J Haba, T Hara, K Hayasaka, H Hayashii, M T Hedges, W-S Hou, T Iijima, K Inami, A Ishikawa, R Itoh, Y Iwasaki, W W Jacobs, I Jaegle, H B Jeon, Y Jin, D Joffe, K K Joo, T Julius, J Kahn, A B Kaliyar, G Karyan, P Katrenko, T Kawasaki, C Kiesling, D Y Kim, H J Kim, J B Kim, K T Kim, M J Kim, S H Kim, Y J Kim, K Kinoshita, P Kodyš, S Korpar, D Kotchetkov, P Križan, P Krokovny, T Kuhr, R Kulasiri, R Kumar, T Kumita, A Kuzmin, Y-J Kwon, J S Lange, I S Lee, C H Li, L Li, Y Li, L Li Gioi, J Libby, D Liventsev, M Lubej, T Luo, M Masuda, D Matvienko, M Merola, K Miyabayashi, H Miyata, R Mizuk, G B Mohanty, S Mohanty, H K Moon, T Mori, R Mussa, E Nakano, M Nakao, T Nanut, K J Nath, Z Natkaniec, M Nayak, M Niiyama, N K Nisar, S Nishida, S Ogawa, S Okuno, H Ono, P Pakhlov, G Pakhlova, B Pal, S Pardi, C-S Park, H Park, S Paul, T K Pedlar, L Pesántez, R Pestotnik, L E Piilonen, K Prasanth, M Ritter, A Rostomyan, H Sahoo, Y Sakai, S Sandilya, L Santelj, T Sanuki, Y Sato, V Savinov, O Schneider, G Schnell, C Schwanda, A J Schwartz, Y Seino, K Senyo, M E Sevior, V Shebalin, C P Shen, T-A Shibata, J-G Shiu, B Shwartz, F Simon, A Sokolov, E Solovieva, M Starič, J F Strube, J Stypula, K Sumisawa, T Sumiyoshi, M Takizawa, U Tamponi, K Tanida, F Tenchini, M Uchida, T Uglov, Y Unno, S Uno, P Urquijo, Y Usov, C Van Hulse, G Varner, V Vorobyev, A Vossen, E Waheed, C H Wang, M-Z Wang, P Wang, M Watanabe, Y Watanabe, E Widmann, K M Williams, E Won, Y Yamashita, H Ye, J Yelton, Y Yook, C Z Yuan, Y Yusa, Z P Zhang, V Zhilich, V Zhukova, V Zhulanov, A Zupanc
We report a study of the decay D^{0}→K_{S}^{0}K_{S}^{0} using 921  fb^{-1} of data collected at or near the ϒ(4S) and ϒ(5S) resonances with the Belle detector at the KEKB asymmetric energy e^{+}e^{-} collider. The measured time-integrated CP asymmetry is A_{CP}(D^{0}→K_{S}^{0}K_{S}^{0})=(-0.02±1.53±0.02±0.17)%, and the branching fraction is B(D^{0}→K_{S}^{0}K_{S}^{0})=(1.321±0.023±0.036±0.044)×10^{-4}, where the first uncertainty is statistical, the second is systematic, and the third is due to the normalization mode (D^{0}→K_{S}^{0}π^{0})...
October 27, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/29215462/liver-transplantation-in-cryptogenic-cirrhosis-outcome-comparisons-between-nash-alcoholic-and-aih-cirrhosis
#9
Paul Joseph Thuluvath, Steven Hanish, Yulia Savva
BACKGROUND: The outcomes of liver transplantation (LT) in patients with cryptogenic cirrhosis (CC) have not been adequately examined except for small case series. We believe that patients currently listed as CC have truly cryptogenic liver disease and may have different post-LT outcomes compared to nonalcoholic steatohepatitis (NASH). METHODS: We compared the post-LT outcomes of adults with CC (n=3241) and compared them with cirrhosis from NASH (n=4089), alcohol (AC, n=7837) and autoimmune hepatitis (AIH, n=1435) using the UNOS database from 2002-16...
December 5, 2017: Transplantation
https://www.readbyqxmd.com/read/29214255/a-green-light-emitting-spontaneously-blinking-fluorophore-based-on-intramolecular-spirocyclization-for-dual-colour-super-resolution-imaging
#10
Shin-Nosuke Uno, Mako Kamiya, Akihiko Morozumi, Yasuteru Urano
We have developed the first green-light-emitting, spontaneously blinking fluorophore (SBF), HEtetTFER. In combination with our near-infrared-light-emitting SBF (HMSiR), HEtetTFER allows dual-colour single-molecule localization microscopy (SMLM) in buffer solution without any additive and without photoactivation.
December 7, 2017: Chemical Communications: Chem Comm
https://www.readbyqxmd.com/read/29211814/overexpression-of-transmembrane-protein-168-in-the-mouse-nucleus-accumbens-induces-anxiety-and-sensorimotor-gating-deficit
#11
Kequan Fu, Yoshiaki Miyamoto, Kazuyuki Sumi, Eriko Saika, Shin-Ichi Muramatsu, Kyosuke Uno, Atsumi Nitta
Transmembrane protein 168 (TMEM168) comprises 697 amino acid residues, including some putative transmembrane domains. It is reported that TMEM168 controls methamphetamine (METH) dependence in the nucleus accumbens (NAc) of mice. Moreover, a strong link between METH dependence-induced adaptive changes in the brain and mood disorders has been evaluated. In the present study, we investigated the effects of accumbal TMEM168 in a battery of behavioral paradigms. The adeno-associated virus (AAV) Tmem168 vector was injected into the NAc of C57BL/6J mice (NAc-TMEM mice)...
2017: PloS One
https://www.readbyqxmd.com/read/29210942/auditory-related-resting-state-fmri-functional-connectivity-in-tinnitus-patients-tinnitus-diagnosis-performance
#12
Shujiro B Minami, Naoki Oishi, Takahisa Watabe, Kimiichi Uno, Kaoru Ogawa
OBJECTIVE: The purpose of the present study was to investigate functional connectivity in tinnitus patients with and without hearing loss, and design the tinnitus diagnosis performance by resting state functional magnetic resonance imaging (rs-fMRI). SUBJECTS AND METHODS: Nineteen volunteers with normal hearing without tinnitus, 18 tinnitus patients with hearing loss, and 11 tinnitus patients without hearing loss were enrolled in this study. The subjects were evaluated with rs-fMRI, and region of interests (ROIs) based correlation analyses were performed using the CONN toolbox version 16 and SPM version 8...
November 28, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/29208957/neuronal-signals-regulate-obesity-induced-%C3%AE-cell-proliferation-by-foxm1-dependent-mechanism
#13
Junpei Yamamoto, Junta Imai, Tomohito Izumi, Hironori Takahashi, Yohei Kawana, Kei Takahashi, Shinjiro Kodama, Keizo Kaneko, Junhong Gao, Kenji Uno, Shojiro Sawada, Tomoichiro Asano, Vladimir V Kalinichenko, Etsuo A Susaki, Makoto Kanzaki, Hiroki R Ueda, Yasushi Ishigaki, Tetsuya Yamada, Hideki Katagiri
Under insulin-resistant conditions such as obesity, pancreatic β-cells proliferate to prevent blood glucose elevations. A liver-brain-pancreas neuronal relay plays an important role in this process. Here, we show the molecular mechanism underlying this compensatory β-cell proliferation. We identify FoxM1 activation in islets from neuronal relay-stimulated mice. Blockade of this relay, including vagotomy, inhibits obesity-induced activation of the β-cell FoxM1 pathway and suppresses β-cell expansion. Inducible β-cell-specific FoxM1 deficiency also blocks compensatory β-cell proliferation...
December 5, 2017: Nature Communications
https://www.readbyqxmd.com/read/29203794/behavioral-impairment-in-shati-nat8l-knockout-mice-via-dysfunction-of-myelination-development
#14
Kazuyuki Sumi, Kyosuke Uno, Hiroshi Noike, Takenori Tomohiro, Yasumaru Hatanaka, Yoko Furukawa-Hibi, Toshitaka Nabeshima, Yoshiaki Miyamoto, Atsumi Nitta
We have identified SHATI/NAT8L in the brain of mice treated with methamphetamine. Recently, it has been reported that SHATI is N-acetyltransferase 8-like protein (NAT8L) that produces N-acetylaspatate (NAA) from aspartate and acetyl-CoA. We have generated SHATI/NAT8L knockout (Shati -/-) mouse which demonstrates behavioral deficits that are not rescued by single NAA supplementation, although the reason for which is still not clarified. It is possible that the developmental impairment results from deletion of SHATI/NAT8L in the mouse brain, because NAA is involved in myelination through lipid synthesis in oligodendrocytes...
December 4, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29199247/utility-of-indocyanine-green-video-angiography-for-sylvian-fissure-dissection-in-subarachnoid-hemorrhage-patients-sylvian-icg-technique
#15
Hiroyuki Toi, Nobuhisa Matsushita, Yukari Ogawa, Keita Kinoshita, Kohei Satoh, Hiroki Takai, Satoshi Hirai, Keijiro Hara, Shunji Matsubara, Masaaki Uno
Indocyanine green (ICG) emits fluorescence in the far-red domain under light excitation. ICG video angiography (ICG-VA) has been established as a useful method to evaluate blood flow in the operative field. We report the usefulness of ICG-VA for Sylvian fissure dissection in patients with subarachnoid hemorrhage (SAH). Subjects comprised 7 patients who underwent ICG-VA before opening the Sylvian fissure during neck clipping for ruptured cerebral aneurysm. We observed contrasted Sylvian veins before opening the Sylvian fissure using surgical microscopes...
December 1, 2017: Neurologia Medico-chirurgica
https://www.readbyqxmd.com/read/29198666/the-pancreas-can-take-the-cold-lower-waitlist-times-through-importation
#16
K Choinski, J P Rocca, J Torabi, K Lorenzen, C Yongue, M E Herbert, T Block, A Chokechanachaisakul, L Kamal, M Kinkhabwala, J A Graham
BACKGROUND: Our center has used a strategy of pancreas importation owing to long regional waitlist times. Here we assess the clinical outcomes and financial considerations of this strategy. METHODS: This was a retrospective observational cohort study of patients who received a pancreas transplant at Montefiore Medical Center (MMC) from 2014 to 2017 (n = 28). Clinical parameters, including hemoglobin A1c and complications, were analyzed. The cohort was compared with United Network for Organ Sharing (UNOS) Region 9 with the use of the UNOS/Organ Procurement and Transplantation Network database...
December 2017: Transplantation Proceedings
https://www.readbyqxmd.com/read/29197266/importance-of-mineral-dust-and-anthropogenic-pollutants-mixing-during-a-long-lasting-high-pm-event-over-east-asia
#17
Zhe Wang, Xiaole Pan, Itsushi Uno, Xueshun Chen, Shigekazu Yamamoto, Haitao Zheng, Jie Li, Zifa Wang
A long-lasting high particulate matter (PM) concentration episode persisted over East Asia from May 24 to June 3, 2014. The Nested Air Quality Prediction Model System (NAQPMS) was used to investigate the mixing of dust and anthropogenic pollutants during this episode. Comparison of observations revealed that the NAQPMS successfully reproduced the time series PM2.5 and PM10 concentrations, as well as the nitrate and sulfate concentrations in fine (aerodynamic diameter ≤ 2.5 μm) and coarse mode (2.5 μm < aerodynamic diameter ≤ 10 μm)...
November 29, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/29194969/sex-based-disparities-in-delisting-for-being-too-sick-for-liver-transplantation
#18
Giuseppe Cullaro, Monika Sarkar, Jennifer C Lai
Women with cirrhosis awaiting liver transplantation (LT) experience higher rates of waitlist mortality than men - it is unknown if practices surrounding delisting for being "too sick" for LT contribute to this disparity beyond death alone. We conducted an analysis of patients listed for LT in the UNOS/OPTN network not receiving exception points from 5/1/07 to 7/1/14 with a primary outcome of delisting with removal codes of "too sick" or "medically unsuitable." A total of 44,388 patients were included, 4,458 were delisted for being "too sick" for LT...
December 1, 2017: American Journal of Transplantation
https://www.readbyqxmd.com/read/29194711/institutional-decision-to-adopt-y90-as-primary-treatment-for-hcc-informed-by-a-1-000-patient-15-year-experience
#19
Riad Salem, Ahmed Gabr, Ahsun Riaz, Ronald Mora, Rehan Ali, Michael Abecassis, Ryan Hickey, Laura Kulik, Daniel Ganger, Steven Flamm, Rohi Atassi, Bassel Atassi, Kent Sato, Al B Benson, Mary F Mulcahy, Nadine Abouchaleh, Ali Al Asadi, Kush Desai, Bartley Thornburg, Michael Vouche, Ali Habib, Juan Caicedo, Frank H Miller, Vahid Yaghmai, Joseph R Kallini, Samdeep Mouli, Robert J Lewandowski
Y90 transarterial radioembolization (TARE) is a transarterial locoregional therapy (LRT) for hepatocellular carcinoma (HCC). In this study, we present overall survival outcomes (OS) in a 1000-patient cohort acquired over a 15-year period. Between December 1, 2003 and March 31, 2017, 1000 patients with HCC were treated with TARE as part of a prospective cohort study. A comprehensive review of toxicity and survival outcomes was performed. Outcomes were stratified by baseline Child-Pugh (CP) class, United Network for Organ Sharing (UNOS) and Barcelona Clinic Liver Cancer (BCLC) staging systems...
December 1, 2017: Hepatology: Official Journal of the American Association for the Study of Liver Diseases
https://www.readbyqxmd.com/read/29194018/customized-design-and-3d-printing-of-face-seal-for-an-n95-filtering-facepiece-respirator
#20
Mang Cai, Hui Li, Shengnan Shen, Yu Wang, Quan Yang
Filtering Facepiece Respirator (FFR) is the most common respirator users in the health care environment utilize for personal protection from outside particles. Comfort and fit are important while wearing an FFR. This paper proposes a novel technology to produce customized face seal design for improving the wearing comfort and fit of FFR wearers. In order to customize the design of face seals, we scanned faces of three subjects using three-dimensional (3D) laser scanning method. A customized face seal for a 3M 8210 N95 FFR for each headform was designed using reverse engineering technique...
December 1, 2017: Journal of Occupational and Environmental Hygiene
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