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https://www.readbyqxmd.com/read/29723284/correction-exploring-the-reproducibility-of-functional-connectivity-alterations-in-parkinson-s-disease
#1
Liviu Badea, Mihaela Onu, Tao Wu, Adina Roceanu, Ovidiu Bajenaru
[This corrects the article DOI: 10.1371/journal.pone.0188196.].
2018: PloS One
https://www.readbyqxmd.com/read/29715769/300-gb-s-im-dd-based-sdm-wdm-pon-with-laserless-onus
#2
Fangdi Bao, Toshio Morioka, Leif K Oxenløwe, Hao Hu
A low-cost, high-speed SDM-WDM-PON architecture is proposed by using a multi-core fiber (MCF) and intensity modulation/directly detection (IM/DD). One of the MCF cores is used for sending laser sources from optical line terminal (OLT) to optical network unit (ONU), thus facilitating laserless and colorless ONUs, and providing ease of network management and maintenance. In addition, the wavelengths of the ONUs are controlled on the OLT side, which also enables flexible optical networks. Thanks to the low inter-core crosstalk of a MCF, downstream (DS) and upstream (US) signals are transmitted independently in different cores of the MCF, not only increasing the aggregated capacity but also avoiding the Rayleigh backscattering noise...
April 2, 2018: Optics Express
https://www.readbyqxmd.com/read/29703004/a-rational-emotive-stress-management-intervention-for-reducing-job-burnout-and-dysfunctional-distress-among-special-education-teachers-an-effect-study
#3
Samuel C Ugwoke, Chiedu Eseadi, Liziana N Onuigbo, Eucharia N Aye, Immaculata N Akaneme, Angie I Oboegbulem, Ifeyinwa O Ezenwaji, Anthonia U Nwobi, Okechukwu O Nwaubani, Bernedeth N Ezegbe, Moses O Ede, Chibueze T Orji, Joseph C Onuoha, Eucharia U Onu, Francisca Okeke, Patricia Agu, Joachim C Omeje, Faith Omeke, Romanus Ugwu, Florence Arumede, Annastasia Eneh
BACKGROUND: Job-related burnout and distress are adverse stress responses which affect individuals in their occupational environment. This study aimed at investigating the effect of a rational-emotive stress management program on job burnout and dysfunctional distress among special education teachers in Nigeria. METHODS: A pretest-posttest randomized control group design was used. The participants in the study were 54 special education teachers. Data were collected using self-report questionnaires...
April 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29690748/the-comparison-of-oncologic-outcomes-between-open-and-laparoscopic-radical-nephroureterectomy-for-the-treatment-of-upper-tract-urothelial-carcinoma-a-korean-multicenter-collaborative-study
#4
Tae Heon Kim, Bumsik Hong, Ho Kyung Seo, Seok Ho Kang, Ja Hyeon Ku, Byong Chang Jeong
Purpose: We compared oncologic outcomes of patients with upper tract urothelial carcinoma (UTUC) who underwent open nephroureterectomy (ONU) or laparoscopic nephroureterectomy (LNU). Materials and Methods: Consecutive cases of ONU and LNU between 2000 and 2012 at five participating institutions were included in this retrospective analysis. Clinical characteristics and pathologic outcomes were compared between the two surgical approaches. The influence of the type of surgical approach on intravesical recurrence-free survival (IVRFS), progression-free survival (PFS), cancer-specific survival (CSS), and overall survival (OS) was analyzed using the Kaplan-Meier method and differences were assessed with the log-rank test...
April 24, 2018: Cancer Research and Treatment: Official Journal of Korean Cancer Association
https://www.readbyqxmd.com/read/29676337/familial-aggregation-of-mood-disorders-among-relatives-of-schizophrenia-probands-admitted-in-a-hospital-in-south-eastern-nigeria-a-family-comparative-study
#5
Justus Uchenna Onu, Jude Uzoma Ohaeri
Introduction: The debate on the current nosological status of schizophrenia and mood disorders as distinct entities is very active among scholars. There is a paucity of genetic epidemiological data to contribute an African perspective to this debate. Aim: This study aimed to assess the morbid risk of mood disorders in the relatives of schizophrenia probands, in comparison with the families of a sample of healthy controls. Subjects and Methods: This study elicited the information on the morbid risk of mood disorders among 5259 relatives of schizophrenia probands (n = 138) and 6734 relatives of healthy controls (n = 138) through direct interview of patients, available relatives of patients and the comparison group...
January 2018: Nigerian Postgraduate Medical Journal
https://www.readbyqxmd.com/read/29540709/optical-pulse-width-modulation-based-tdm-pon-monitoring-with-asymmetric-loop-in-onus
#6
Xuan Zhang, Xiaohan Sun
We propose a time division multiplexing passive optical network (TDM-PON) monitoring scheme based on the optical pulse width modulation (OPWM) by using a simple asymmetric loop (AL) located near the optical network unit (ONU). Various pulse widths can be easily obtained by configuring the appropriate length of the patchcord used to generate the path difference between two branches of a 1 × 2 splitter. Different wavelengths can be assigned to the same pulse width, which can further increase the network size...
March 14, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29535321/sharing-of-photobionts-in-sympatric-populations-of-thamnolia-and-cetraria-lichens-evidence-from-high-throughput-sequencing
#7
Ioana Onuț-Brännström, Mitchell Benjamin, Douglas G Scofield, Starri Heiðmarsson, Martin G I Andersson, Eva S Lindström, Hanna Johannesson
In this study, we explored the diversity of green algal symbionts (photobionts) in sympatric populations of the cosmopolitan lichen-forming fungi Thamnolia and Cetraria. We sequenced with both Sanger and Ion Torrent High-Throughput Sequencing technologies the photobiont ITS-region of 30 lichen thalli from two islands: Iceland and Öland. While Sanger recovered just one photobiont genotype from each thallus, the Ion Torrent data recovered 10-18 OTUs for each pool of 5 lichen thalli, suggesting that individual lichens can contain heterogeneous photobiont populations...
March 13, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29461914/comparison-of-open-versus-laparoscopic-versus-hand-assisted-laparoscopic-nephroureterectomy-a-systematic-review-and-meta-analysis
#8
Akbar Nouralizadeh, Shahin Tabatabaei, Abbas Basiri, Nasser Simforoosh, Mohammad Soleimani, Babak Javanmard, Anahita Ansari, Hamidreza Shemshaki
BACKGROUND: A systematic analysis of the evidence regarding oncological, perioperative and postoperative outcomes of open nephroureterectomy (ONU), laparoscopic nephroureterectomy (LNU), and hand-assisted laparoscopic nephroureterectomy (HALNU) was designed. METHODS: The summarized data were abstracted from 52 original research articles representing 19,195 patients. PubMed/Medline, Scopus, Google Scholar, EMBASE, and the Cochrane Library were reviewed in March 2017, following PRISMA framework...
February 20, 2018: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/29435873/oncologic-outcomes-for-open-and-laparoscopic-radical-nephroureterectomy-in-patients-with-upper-tract-urothelial-carcinoma
#9
Koichi Kido, Shingo Hatakeyama, Naoki Fujita, Hayato Yamamoto, Yuki Tobisawa, Tohru Yoneyama, Takahiro Yoneyama, Yasuhiro Hashimoto, Takuya Koie, Ikuya Iwabuchi, Masaru Ogasawara, Toshiaki Kawaguchi, Chikara Ohyama
BACKGROUND: Oncologic benefits of laparoscopic radical nephroureterectomy (LNU) are unclear. We aimed to evaluate the impact of surgical approach for radical nephroureterectomy on oncologic outcomes in patients with locally advanced upper tract urothelial carcinoma (UTUC). METHODS: Of 426 patients who underwent radical nephroureterectomy at five medical centers between February 1995 and February 2017, we retrospectively investigated oncological outcomes in 229 with locally advanced UTUC (stages cT3-4 and/or cN+)...
February 12, 2018: International Journal of Clinical Oncology
https://www.readbyqxmd.com/read/29276414/perceptions-and-practice-of-epidural-analgesia-among-women-attending-antenatal-clinic-in-fetha
#10
Paul O Ezeonu, Okechukwu Bonaventure Anozie, Fidelis A Onu, Chidi U Esike, Johnbosco E Mamah, Lucky O Lawani, Robinson C Onoh, Emmanuel Okechukwu Ndukwe, Richard Lawrence Ewah, Rita Onyinyechi Anozie
Background: The pain of childbirth is arguably the most severe pain that most women will endure in their lifetime. Epidural analgesia is widely used as an effective method of pain relief in labor. It provides almost complete relief of pain if administered timely, and does not affect the progress of the first stage labor. Objectives: The objective of this study was to determine the awareness and utilization of epidural analgesia in labor in pregnant women attending the antenatal clinic at Federal Teaching Hospital, Abakaliki (FETHA)...
2017: International Journal of Women's Health
https://www.readbyqxmd.com/read/29187324/pain-in-the-elderly-and-cognition-state-of-play
#11
Rodrigue Deleens, Gisèle Pickering, Yacine Hadjiat
Cognitive impairment is commonly associated with the pain experience. This deterioration regarding several cognitive domains such as attention, speed of information processing, memory, learning and executive functions, represents a major obstacle to daily activities and mobility especially in the elderly for whom a decrease in mobility is a significant risk factor for death and disability. Regarding the demographic rising in the elderly population expected by 2050 (the proportion of persons aged 60 and above is expected to double according to ONU estimate) and the high prevalence of pain in this age reaching 80% in nursing homes, clinicians should be better aware of the links between pain and cognition in this population's segment so that they offer each patient an appropriate treatment...
December 1, 2017: Gériatrie et Psychologie Neuropsychiatrie du Vieillissement
https://www.readbyqxmd.com/read/29182621/exploring-the-reproducibility-of-functional-connectivity-alterations-in-parkinson-s-disease
#12
Liviu Badea, Mihaela Onu, Tao Wu, Adina Roceanu, Ovidiu Bajenaru
Since anatomic MRI is presently not able to directly discern neuronal loss in Parkinson's Disease (PD), studying the associated functional connectivity (FC) changes seems a promising approach toward developing non-invasive and non-radioactive neuroimaging markers for this disease. While several groups have reported such FC changes in PD, there are also significant discrepancies between studies. Investigating the reproducibility of PD-related FC changes on independent datasets is therefore of crucial importance...
2017: PloS One
https://www.readbyqxmd.com/read/29103371/prolonged-incarceration-and-prisoners-wellbeing-livid-experiences-of-awaiting-trial-pre-trial-remand-prisoners-in-nigeria
#13
Charles T Orjiakor, Dorothy I Ugwu, John E Eze, Leonard I Ugwu, Peace N Ibeagha, Desmond U Onu
PURPOSE: Awaiting trial prisoners (ATPs) are represented in prisons globally, and may stay for long periods in detention. This group is however underrepresented in literature on incarcerated persons. We aim to explore the lived experiences of ATPs detained for prolonged years in a sub-Saharan country; examining what they make of their status and how their conditions have affected their wellbeing. METHOD: Eight inmates awaiting trial for armed robbery and murder offences, held for between 8 years and 15 years participated in a focus group discussion...
December 2017: International Journal of Qualitative Studies on Health and Well-being
https://www.readbyqxmd.com/read/29066013/role-of-surgical-approach-on-lymph-node-dissection-yield-and-survival-in-patients-with-upper-tract-urothelial-carcinoma
#14
Andrew T Lenis, Nicholas M Donin, Izak Faiena, Amirali Salmasi, David C Johnson, Alexandra Drakaki, Kiran Gollapudi, Jeremy Blumberg, Arie Belldegrun, Allan Pantuck, Karim Chamie
OBJECTIVES: With increasing utilization of robot-assisted surgery in urologic oncology, robotic nephroureterectomy (RNU) is becoming the surgical modality of choice for patients with upper tract urothelial carcinoma (UTUC). The role of surgical approach on lymph node dissection (LND) and lymph node (LN) yield is unclear, and potential therapeutic effects are unknown. Here we analyze the effects of surgical approach on LN yield, performance of LND, and overall survival (OS). METHODS AND MATERIALS: Patients with UTUC who underwent nephroureterectomy from 2010 to 2013 were identified in the National Cancer Database...
January 2018: Urologic Oncology
https://www.readbyqxmd.com/read/29060293/a-semi-markov-chain-approach-to-modeling-respiratory-patterns-prior-to-extubation-in-preterm-infants
#15
Charles C Onu, Lara J Kanbar, Wissam Shalish, Karen A Brown, Guilherme M Sant'Anna, Robert E Kearney, Doina Precup
After birth, extremely preterm infants often require specialized respiratory management in the form of invasive mechanical ventilation (IMV). Protracted IMV is associated with detrimental outcomes and morbidities. Premature extubation, on the other hand, would necessitate reintubation which is risky, technically challenging and could further lead to lung injury or disease. We present an approach to modeling respiratory patterns of infants who succeeded extubation and those who required reintubation which relies on Markov models...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28767584/effects-of-a-rational-emotive-health-education-intervention-on-stress-management-and-irrational-beliefs-among-technical-college-teachers-in-southeast-nigeria
#16
RANDOMIZED CONTROLLED TRIAL
Samuel C Ugwoke, Chiedu Eseadi, Chima C Igbokwe, Gertrude T U Chiaha, Okechukwu O Nwaubani, Chibueze Tobias Orji, Leonard T Ugwuanyi, Ifeoma S Chukwuma, Edith C Edikpa, Vera N Ogakwu, Eucharia A Onu, Patricia Agu, Ujunwa A Nwobi, Faith Omeke, Francisca C Okeke, Rita N Ezema, Lawretta I Abugu
BACKGROUND: Stress is the product of how an individual reacts and adapts to the specific demands and threats they encounter while carrying out given tasks. The main purpose of this study was to investigate the effects of a rational-emotive health education intervention (REHEI) on stress management, and irrational beliefs in a sample of technical college teachers in Southeast Nigeria. METHOD: The study design was a pretest-posttest control group. Repeated measures analysis of variance, paired t test and Mann-Whitney U tests were used to analyze the data collected...
August 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28666757/a-novel-chimeric-hepatitis-b-virus-s-pres1-antigen-produced-in-mammalian-and-plant-cells-elicits-stronger-humoral-and-cellular-immune-response-than-the-standard-vaccine-constituent-s-protein
#17
Mihaela-Olivia Dobrica, Catalin Lazar, Lisa Paruch, Hanne Skomedal, Hege Steen, Sissel Haugslien, Catalin Tucureanu, Iuliana Caras, Adrian Onu, Sonya Ciulean, Alexandru Branzan, Jihong Liu Clarke, Crina Stavaru, Norica Branza-Nichita
Chronic Hepatitis B Virus (HBV) infection leads to severe liver pathogenesis associated with significant morbidity and mortality. As no curable medication is yet available, vaccination remains the most cost-effective approach to limit HBV spreading and control the infection. Although safe and efficient, the standard vaccine based on production of the small (S) envelope protein in yeast fails to elicit an effective immune response in about 10% of vaccinated individuals, which are at risk of infection. One strategy to address this issue is the development of more immunogenic antigens...
June 27, 2017: Antiviral Research
https://www.readbyqxmd.com/read/28537436/utilization-and-outcomes-of-nephroureterectomy-for-upper-tract-urothelial-carcinoma-by-surgical-approach
#18
Joseph F Rodriguez, Vignesh T Packiam, William R Boysen, Scott C Johnson, Zachary L Smith, Norm D Smith, Arieh L Shalhav, Gary D Steinberg
OBJECTIVES: To compare outcomes and survival of open-, robotic-, and laparoscopic nephroureterectomy (ONU, RNU, LNU) using population-based data. METHODS: Using the National Cancer Database, we identified patients who underwent nephroureterectomy for localized upper tract urothelial carcinoma between 2010 and 2013. Demographic and clinicopathologic characteristics were compared among the three operative approaches. Multivariate regression analyses were used to determine the impact of approach on performance of lymphadenectomy (LND), positive surgical margins (PSM), and overall survival (OS)...
July 2017: Journal of Endourology
https://www.readbyqxmd.com/read/28522928/systematic-review-of-open-versus-laparoscopic-versus-robot-assisted-nephroureterectomy
#19
Emma Mullen, Kamran Ahmed, Ben Challacombe
Upper tract urothelial carcinoma is a relatively uncommon malignancy. The gold standard treatment for this type of neoplasm is an open radical nephroureterectomy with excision of the bladder cuff. This systematic review compares the perioperative and oncologic outcomes for the open surgical method with the alternative surgical management options of laparoscopic nephroureterectomy and robot-assisted nephroureterectomy (RANU). MEDLINE, EMBASE, PubMed, and Cochrane Library databases were searched using a sensitive search strategy...
2017: Reviews in Urology
https://www.readbyqxmd.com/read/28512596/in-vitro-screening-for-protein-tyrosine-phosphatase-1b-and-dipeptidyl-peptidase-iv-inhibitors-from-selected-nigerian-medicinal-plants
#20
Yusuf Saidu, Suleiman Alhaji Muhammad, Abdullahi Yahaya Abbas, Andrew Onu, Ibrahim Mohammed Tsado, Luba Muhammad
BACKGROUND/AIM: Protein tyrosine phosphatase 1B (PTP 1B) and dipeptidyl peptidase IV (DPP IV) have been identified as one of the drug targets for the treatment of Type-2 diabetes. This study was designed to screen for PTP 1B and DPP-IV inhibitors from some Nigerian medicinal plants. MATERIALS AND METHODS: PTP 1B and DPP-IV drug discovery kits from Enzo Life Sciences were used to investigate in vitro inhibitory effect of crude methanolic extract of 10 plants; Mangifera indica , Moringa oleifera , Acacia nilotica , Arachis hypogaea , Senna nigricans , Azadirachta indica , Calotropis procera , Leptadenia hastata , Ziziphus mauritiana , and Solanum incanum ...
April 2017: Journal of Intercultural Ethnopharmacology
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