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https://www.readbyqxmd.com/read/29356418/electrolytes-sei-formation-and-binders-a-review-of-nonelectrode-factors-for-sodium-ion-battery-anodes
#1
REVIEW
Clement Bommier, Xiulei Ji
Through intense effort in recent years, knowledge of Na-ion batteries has been advanced significantly, pertaining to electrodes. Often, such progress has been accompanied by using a convenient choice of electrolyte or binder. Nevertheless, it has been witnessed that "external" factors to electrodes, such as electrolytes, solid electrolyte interphase, and binders, affect the functions of electrodes profoundly. And generally, certain types of electrodes favor some electrolytes or binders. With a rapidly increasing number of publications in the area, trends in terms of electrolytes and binders are possibly exploitable...
January 22, 2018: Small
https://www.readbyqxmd.com/read/29356411/silicon-based-anodes-for-lithium-ion-batteries-from-fundamentals-to-practical-applications
#2
REVIEW
Kun Feng, Matthew Li, Wenwen Liu, Ali Ghorbani Kashkooli, Xingcheng Xiao, Mei Cai, Zhongwei Chen
Silicon has been intensively studied as an anode material for lithium-ion batteries (LIB) because of its exceptionally high specific capacity. However, silicon-based anode materials usually suffer from large volume change during the charge and discharge process, leading to subsequent pulverization of silicon, loss of electric contact, and continuous side reactions. These transformations cause poor cycle life and hinder the wide commercialization of silicon for LIBs. The lithiation and delithiation behaviors, and the interphase reaction mechanisms, are progressively studied and understood...
January 22, 2018: Small
https://www.readbyqxmd.com/read/29355860/interface-engineered-in-situ-anchoring-of-co9s8-nanoparticles-into-a-multiple-doped-carbon-matrix-highly-efficient-zinc-air-batteries
#3
Yang Li, Wei Zhou, Juncai Dong, Yun Luo, Pengfei An, Juan Liu, Xin Wu, Guilan Xu, Huabin Zhang, Jian Zhang
Interface modification is an effective and promising route for developing functional electrocatalysts. However, researchers have not created a reliable method to optimize the interfaces of components existing in electrocatalysts, although it is very crucial for the technological development of high-performance electrodes. Here, we develop a strategy aiming at the in situ anchorage of Co9S8 nanoparticles into a nitrogen (N), sulfur (S) co-implanted three-dimensional carbon matrix (Co9S8@NSCM) as a highly active and durable nonprecious metal electrocatalyst for the oxygen reduction reaction (ORR) and oxygen evolution reaction (OER) in alkaline medium...
January 22, 2018: Nanoscale
https://www.readbyqxmd.com/read/29355708/juvenile-hormone-and-sesquiterpenoids-in-arthropods-biosynthesis-signaling-and-role-of-microrna
#4
REVIEW
Zhe Qu, William G Bendena, Stephen S Tobe, Jerome H L Hui
Arthropod molting and reproduction are precisely controlled by the levels of sesquiterpenoids, a class of C15 hormones derived from three isoprene units. The two major functional arthropod sesquiterpenoids are juvenile hormone (JH) and methyl farnesoate (MF). In hemimetabolous insects (such as the aphids, bugs, and cockroaches) and holometabolous insects (such as beetles, bees, butterflies, and flies), dramatic decrease in the titers of JH and/or MF promote metamorphosis from larvae to adults either directly or through an intermediate pupal stage, respectively...
January 17, 2018: Journal of Steroid Biochemistry and Molecular Biology
https://www.readbyqxmd.com/read/29355582/targeting-heat-shock-protein-70-as-an-antiviral-strategy-against-grass-carp-reovirus-infection
#5
Li-Peng Shan, Xiao-Hui Chen, Fei Ling, Bin Zhu, Gao-Xue Wang
Grass carp (Ctenopharyngodon idella) hemorrhagic disease, caused by grass carp reovirus (GCRV), has been a serious problem in grass carp aquaculture for several decades. Characterization of the primary host factors associated with host-virus interaction is critical for understanding how a virus infects its host cell and these host factors can be antiviral targets. This study aimed to screen host factors that interacted with GCRV in the C. idella kidney (CIK) cells and used them as antiviral targets. Twelve proteins were identified by virus overlay protein binding assay and LC-MS-MS...
January 16, 2018: Virus Research
https://www.readbyqxmd.com/read/29355502/the-influence-of-temperature-and-salinity-on-mortality-of-recently-recruited-blue-crabs-callinectes-sapidus-naturally-infected-with-hematodinium-perezi-dinoflagellata
#6
Juan Pablo Huchin-Mian, Hamish J Small, Jeffrey D Shields
The parasitic dinoflagellate Hematodinium perezi is highly prevalent in juvenile blue crabs, Callinectes sapidus, along the eastern seaboard of the USA. Although the parasite is known to kill adult crabs, the mortality rate of naturally infected juvenile crabs remains unknown. We analyzed the influence of temperature and salinity on the mortality of recently recruited blue crab that were naturally infected with H. perezi. Over 492 juvenile crabs (infected, n=282; uninfected controls, n=210) were held individually in six-well plates and held at six temperatures (4, 10, 15, 20, 25, and 30 °C) or three salinities (5, 15, and 30 psu) for a maximum of 90 days...
January 18, 2018: Journal of Invertebrate Pathology
https://www.readbyqxmd.com/read/29354879/metagenomic-signatures-of-microbial-communities-in-deep-sea-hydrothermal-sediments-of-azores-vent-fields
#7
Teresa Cerqueira, Cristina Barroso, Hugo Froufe, Conceição Egas, Raul Bettencourt
The organisms inhabiting the deep-seafloor are known to play a crucial role in global biogeochemical cycles. Chemolithoautotrophic prokaryotes, which produce biomass from single carbon molecules, constitute the primary source of nutrition for the higher organisms, being critical for the sustainability of food webs and overall life in the deep-sea hydrothermal ecosystems. The present study investigates the metabolic profiles of chemolithoautotrophs inhabiting the sediments of Menez Gwen and Rainbow deep-sea vent fields, in the Mid-Atlantic Ridge...
January 21, 2018: Microbial Ecology
https://www.readbyqxmd.com/read/29354353/mineralization-of-high-concentrations-of-the-endocrine-disruptor-dibutyl-phthalate-by-fusarium-culmorum
#8
Miriam Ahuactzin-Pérez, Saúl Tlecuitl-Beristain, Jorge García-Dávila, Ericka Santacruz-Juárez, Manuel González-Pérez, María Concepción Gutiérrez-Ruíz, Carmen Sánchez
Dibutyl phthalate (DBP) is a widely used plasticizer, whose presence in the environment as a pollutant raises concern because of its endocrine-disrupting toxicity. Growth kinetics, glucose uptake, biodegradation constant of DBP (k), half-life of DBP biodegradation (t1/2) and percentage of removal efficiency (%E) were evaluated for Fusarium culmorum grown on media containing glucose and different concentrations of DBP (500 and 1000 mg/l). Intermediate compounds of biodegraded DBP were identified by GC-MS and a novel DBP biodegradation pathway was proposed on the basis of the intermolecular flow of electrons of the intermediates identified using quantum chemical modeling...
January 2018: 3 Biotech
https://www.readbyqxmd.com/read/29353164/a-phase-ii-study-of-nab-paclitaxel-in-combination-with-ramucirumab-in-patients-with-previously-treated-advanced-gastric-cancer
#9
Hideaki Bando, Hideki Shimodaira, Kazumasa Fujitani, Atsuo Takashima, Kensei Yamaguchi, Norisuke Nakayama, Takehiro Takahashi, Eiji Oki, Mizutomo Azuma, Tomohiro Nishina, Shuichi Hironaka, Yoshito Komatsu, Kohei Shitara
BACKGROUND: Nanoparticle albumin-bound (nab)-paclitaxel was developed to improve paclitaxel solubility and does not need premedication to avoid infusion-related reactions associated with solvent-based (sb)-paclitaxel. We conducted a phase II trial to investigate the efficacy and safety of nab-paclitaxel plus ramucirumab combination therapy for previously treated advanced gastric cancer. PATIENTS AND METHODS: Patients with unresectable advanced gastric cancer refractory to first-line chemotherapy were administered nab-paclitaxel 100 mg/m2 intravenously on days 1, 8 and 15, plus ramucirumab 8 mg/kg intravenously on days 1 and 15 of a 28-day cycle...
January 17, 2018: European Journal of Cancer
https://www.readbyqxmd.com/read/29352733/localization-of-palmitoylated-and-activated-g-protein-%C3%AE-subunit-in-dictyostelium-discoideum
#10
Sarah Alamer, Yusuke Kageyama, Robert E Gundersen
Guanine nucleotide-binding proteins (G proteins) act as molecular switches to regulate many fundamental cellular processes. The lipid modification, palmitoylation, can be considered as a key factor for proper G protein function and plasma membrane localization. In Dictyostelium discoidum, Gα2 is essential for the chemotactic response to cAMP in their developmental life cycle. However, the regulation of Gα2 with respect to palmitoylation, activation and Gβγ association is less clear. In this study, Gα2 is shown to be palmitoylated on Cys-4 by [3 H]palmitate labeling...
January 20, 2018: Journal of Cellular Biochemistry
https://www.readbyqxmd.com/read/29352322/qportal-a-platform-for-data-driven-biomedical-research
#11
Christopher Mohr, Andreas Friedrich, David Wojnar, Erhan Kenar, Aydin Can Polatkan, Marius Cosmin Codrea, Stefan Czemmel, Oliver Kohlbacher, Sven Nahnsen
Modern biomedical research aims at drawing biological conclusions from large, highly complex biological datasets. It has become common practice to make extensive use of high-throughput technologies that produce big amounts of heterogeneous data. In addition to the ever-improving accuracy, methods are getting faster and cheaper, resulting in a steadily increasing need for scalable data management and easily accessible means of analysis. We present qPortal, a platform providing users with an intuitive way to manage and analyze quantitative biological data...
2018: PloS One
https://www.readbyqxmd.com/read/29352288/phospholipid-scramblase-1-interacts-with-influenza-a-virus-np-impairing-its-nuclear-import-and-thereby-suppressing-virus-replication
#12
Weiyu Luo, Jie Zhang, Libin Liang, Guangwen Wang, Qibing Li, Pengyang Zhu, Yuan Zhou, Junping Li, Yuhui Zhao, Nan Sun, Shanyu Huang, Chenchen Zhou, Yu Chang, Pengfei Cui, Pucheng Chen, Yongping Jiang, Guohua Deng, Zhigao Bu, Chengjun Li, Li Jiang, Hualan Chen
Transcription and replication of the influenza A virus (IAV) genome occur in the nucleus of infected cells and are carried out by the viral ribonucleoprotein complex (vRNP). As a major component of the vRNP complex, the viral nucleoprotein (NP) mediates the nuclear import of the vRNP complex via its nuclear localization signals (NLSs). Clearly, an effective way for the host to antagonize IAV infection would be by targeting vRNP nuclear import. Here, we identified phospholipid scramblase 1 (PLSCR1) as a binding partner of NP by using a yeast two-hybrid (Y2H) screen...
January 19, 2018: PLoS Pathogens
https://www.readbyqxmd.com/read/29352273/binder-free-sheet-type-all-solid-state-batteries-with-enhanced-rate-capabilities-and-high-energy-densities
#13
Mari Yamamoto, Yoshihiro Terauchi, Atsushi Sakuda, Masanari Takahashi
All-solid-state batteries using inorganic solid electrolytes are considered promising energy storage systems because of their safety and long life. Stackable and compact sheet-type all-solid-state batteries are urgently needed for industrial applications such as smart grids and electric vehicles. A binder is usually indispensable to the construction of sheet-type batteries; however, it can decrease the power and cycle performance of the battery. Here we report the first fabrication of a binder-free sheet-type battery...
January 19, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29352115/stil-balancing-primary-microcephaly-and-cancer
#14
REVIEW
Patwardhan Dhruti, Mani Shyamala, Passemard Sandrine, Gressens Pierre, El Ghouzzi Vincent
Cell division and differentiation are two fundamental physiological processes that need to be tightly balanced to achieve harmonious development of an organ or a tissue without jeopardizing its homeostasis. The role played by the centriolar protein STIL is highly illustrative of this balance at different stages of life as deregulation of the human STIL gene expression has been associated with either insufficient brain development (primary microcephaly) or cancer, two conditions resulting from perturbations in cell cycle and chromosomal segregation...
January 19, 2018: Cell Death & Disease
https://www.readbyqxmd.com/read/29351743/phosphate-signaling-through-alternate-conformations-of-the-pstscab-phosphate-transporter
#15
Ramesh K Vuppada, Colby R Hansen, Kirsta A P Strickland, Keilen M Kelly, William R McCleary
BACKGROUND: Phosphate is an essential compound for life. Escherichia coli employs a signal transduction pathway that controls the expression of genes that are required for the high-affinity acquisition of phosphate and the utilization of alternate sources of phosphorous. These genes are only expressed when environmental phosphate is limiting. The seven genes for this signaling pathway encode the two-component regulatory proteins PhoB and PhoR, as well as the high-affinity phosphate transporter PstSCAB and an auxiliary protein called PhoU...
January 19, 2018: BMC Microbiology
https://www.readbyqxmd.com/read/29351667/what-to-expect-and-when-benznidazole-toxicity-in-chronic-chagas-disease-treatment
#16
E Aldasoro, E Posada, A Requena-Méndez, A Calvo-Cano, N Serret, A Casellas, S Sanz, D Soy, M J Pinazo, J Gascon
Background: Benznidazole is one of the two most effective antiparasitic drugs for Chagas' disease treatment. However, knowledge about its toxicity profile is mostly based on post-marketing observational studies. Objectives: Our study combines data from two prospective clinical trials designed to assess the safety of the drug newly produced by ELEA Laboratories (Abarax®). Methods: Eligible participants were selected using a consecutive sampling strategy in the CINEBENZ and BIOMARCHA studies between 2013 and 2016 (EUDRACT 2011-002900-34 and 2012-002645-38, respectively, and clinicaltrials...
January 16, 2018: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/29351591/could-seasonally-deteriorating-environments-favour-the-evolution-of-autogamous-selfing-and-a-drought-escape-physiology-through-indirect-selection-a-test-of-the-time-limitation-hypothesis-using-artificial-selection-in-clarkia
#17
Simon K Emms, Alisa A Hove, Leah S Dudley, Susan J Mazer, Amy S Verhoeven
Background and Aims: The evolution of selfing from outcrossing may be the most common transition in plant reproductive systems and is associated with a variety of ecological circumstances and life history strategies. The most widely discussed explanation for these associations is the reproductive assurance hypothesis - the proposition that selfing is favoured because it increases female fitness when outcross pollen receipt is limited. Here an alternative explanation, the time limitation hypothesis, is addressed, one scenario of which proposes that selfing may evolve as a correlated response to selection for a faster life cycle in seasonally deteriorating environments...
January 17, 2018: Annals of Botany
https://www.readbyqxmd.com/read/29351234/contribution-of-the-ratio-of-tocopherol-homologs-to-the-oxidative-stability-of-commercial-vegetable-oils
#18
Mathias Zaunschirm, Marc Pignitter, Julia Kienesberger, Natalie Hernler, Christoph Riegger, Manfred Eggersdorfer, Veronika Somoza
The antioxidant activity of tocopherols in vegetable oils was shown to chiefly depend on the amount and the tocopherol homolog present. However, the most effective ratio of tocopherol homologs with regard to the antioxidant capacity has not been elucidated so far. The present study analyzed the effect of different tocopherol concentrations, homologs and ratios of homologs on markers of lipid oxidation in the most commonly consumed vegetable oils (canola, sunflower, soybean oil) stored in a 12 h light/dark cycle at 22 ± 2 °C for 56 days under retail/household conditions...
January 19, 2018: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29351130/comparative-effectiveness-of-low-volume-time-efficient-resistance-training-versus-endurance-training-in-patients-with-heart-failure
#19
Gregers Winding Munch, Jaya Birgitte Rosenmeier, Morten Petersen, Anders Rasmussen Rinnov, Ulrik Winning Iepsen, Bente Klarlund Pedersen, Stefan Peter Mortensen
PURPOSE: Cardiorespiratory fitness is positively related to heart failure (HF) prognosis, but lack of time and low energy are barriers for adherence to exercise. We, therefore, compared the effect of low-volume time-based resistance exercise training (TRE) with aerobic moderate-intensity cycling (AMC) on maximal and submaximal exercise capacity, health-related quality of life, and vascular function. METHODS: Twenty-eight HF patients (New York Heart Association class I-II) performed AMC (n = 14) or TRE (n = 14)...
January 18, 2018: Journal of Cardiopulmonary Rehabilitation and Prevention
https://www.readbyqxmd.com/read/29351113/fatigue-failure-of-external-hexagon-connections-on-cemented-implant-supported-crowns
#20
João Malta Barbosa, Daniel Navarro da Rocha, Ronaldo Hirata, Gileade Freitas, Estevam A Bonfante, Paulo G Coelho
PURPOSE: To evaluate the probability of survival and failure modes of different external hexagon connection systems restored with anterior cement-retained single-unit crowns. The postulated null hypothesis was that there would be no differences under accelerated life testing. MATERIALS AND METHODS: Fifty-four external hexagon dental implants (∼4 mm diameter) were used for single cement-retained crown replacement and divided into 3 groups: (3i) Full OSSEOTITE, Biomet 3i (n = 18); (OL) OEX P4, Osseolife Implants (n = 18); and (IL) Unihex, Intra-Lock International (n = 18)...
January 17, 2018: Implant Dentistry
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