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Iron and anemia and children

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https://www.readbyqxmd.com/read/29791933/infantile-basal-ganglia-stroke-after-mild-head-trauma-associated-with-mineralizing-angiopathy-of-lenticulostriate-arteries-an-under-recognized-entity
#1
Sandra P Toelle, Tamara Avetisyan, Nune Kuyumjyan, Biayna Sukhudyan, Eugen Boltshauser, Annette Hackenberg
Basal ganglia infarction in young children, mostly after mild head trauma, has been repeatedly reported. The pathogenesis and the risk factors are not fully understood. Lenticulostriate vasculopathy, usually referred to as basal ganglia calcification, is discussed as one of them. We describe five young (7-13 months old on presentation) male children who suffered from hemiparesis due to ischemic stroke of the basal ganglia, four of them after minor head trauma. All of them had calcification in the basal ganglia visible on computed tomography or cranial ultrasound but not on magnetic resonance imaging...
May 23, 2018: Neuropediatrics
https://www.readbyqxmd.com/read/29782390/suspecting-hyperferritinemic-sepsis-in-iron-deficient-population-do-we-need-a-lower-plasma-ferritin-threshold
#2
Swarup Ghosh, Arun K Baranwal, Prateek Bhatia, Karthi Nallasamy
OBJECTIVES: Hyperferritinemia is being suggested to identify patients with sepsis-induced macrophage activation syndrome for early intervention. However, data among iron-deficient children are scarce. This study was planned to explore the biological behavior of plasma ferritin in children from communities with a high frequency of iron deficiency with septic shock and its association with the outcome. DESIGN: Prospective observational study. SETTING: Tertiary care teaching hospital in a low-middle income economy of South Asia...
May 18, 2018: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/29772478/bacillus-thuringiensis-cry5b-protein-as-a-new-pan-hookworm-cure
#3
Yan Hu, Thanh-Thanh Nguyen, Alice C Y Lee, Joseph F Urban, Melanie M Miller, Bin Zhan, David J Koch, Jason B Noon, Ambily Abraham, Ricardo Toshio Fujiwara, Dwight D Bowman, Gary R Ostroff, Raffi V Aroian
Hookworms are intestinal nematode parasites that infect nearly half a billion people and are globally one of the most important contributors to iron-deficiency anemia. These parasites have significant impacts in developing children, pregnant women and working adults. Of all the soil-transmitted helminths or nematodes (STNs), hookworms are by far the most important, with disease burdens conservatively estimated at four million DALYs (Disability-Adjusted Life Years) and with productivity losses of up to US$139 billion annually...
May 4, 2018: International Journal for Parasitology, Drugs and Drug Resistance
https://www.readbyqxmd.com/read/29769814/combined-deficiencies-of-25-hydroxyvitamin-d-and-anemia-in-preschool-children-with-severe-early-childhood-caries-a-case-control-study
#4
Shannon Deane, Robert J Schroth, Atul Sharma, Celia Rodd
Background: Severe early childhood caries (S-ECC) is common and has adverse affects on children's health. Children with S-ECC have been shown to have anemia or vitamin D deficiency. No studies have assessed the presence of combined deficiencies with S-ECC. The purpose of our study was to examine whether those with S-ECC had a higher prevalence of combined anemia and low 25-hydroxyvitamin D (25(OH)D) compared to controls. Covariates associated with elevated parathyroid hormone (PTH), previously noted in S-ECC, were examined...
May 2018: Paediatrics & Child Health
https://www.readbyqxmd.com/read/29767699/impact-of-double-fortified-salt-with-iron-and-iodine-on-hemoglobin-anemia-and-iron-deficiency-anemia-a-systematic-review-and-meta-analysis
#5
María J Ramírez-Luzuriaga, Leila M Larson, Venkatesh Mannar, Reynaldo Martorell
Double-fortified salt (DFS) containing iron and iodine has been proposed as a feasible and cost-effective alternative for iron fortification in low- and middle-income countries (LMICs). We conducted a systematic review and meta-analysis from randomized and quasi-randomized controlled trials to 1) assess the effect of DFS on biomarkers of iron status and the risk of anemia and iron deficiency anemia (IDA) and 2) evaluate differential effects of DFS by study type (efficacy or effectiveness), population subgroups, iron formulation (ferrous sulfate, ferrous fumarate, and ferric pyrophosphate), iron concentration, duration of intervention, and study quality...
May 1, 2018: Advances in Nutrition
https://www.readbyqxmd.com/read/29765934/autoimmune-gastritis-in-the-pediatric-age-an-underestimated-condition-report-of-two-cases-and-review
#6
Chiara Saglietti, Amedeo Sciarra, Karim Abdelrahman, Vanessa Schneider, Arti Karpate, Andreas Nydegger, Christine Sempoux
Background: Diagnosis of pediatric autoimmune gastritis (AIG) in children is important due to poor outcome and risk of malignancy. This condition is often underestimated in the clinico-pathologic diagnostic work-up, leading to delayed time-to-diagnosis. To increase the awareness of this condition in the pediatric population, we present two cases encountered at our institution, discuss their clinical, biological, and histological presentations in relation with evidence from the literature, and propose an algorithm for diagnosis and follow-up of AIG in children...
2018: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/29755496/banana21-from-gene-discovery-to-deregulated-golden-bananas
#7
REVIEW
Jean-Yves Paul, Robert Harding, Wilberforce Tushemereirwe, James Dale
Uganda is a tropical country with a population in excess of 30 million, >80% of whom live in rural areas. Bananas ( Musa spp.) are the staple food of Uganda with the East African Highland banana, a cooking banana, the primary starch source. Unfortunately, these bananas are low in pro-vitamin A (PVA) and iron and, as a result, banana-based diets are low in these micronutrients which results in very high levels of inadequate nutrition. This inadequate nutrition manifests as high levels of vitamin A deficiency, iron deficiency anemia, and stunting in children...
2018: Frontiers in Plant Science
https://www.readbyqxmd.com/read/29747646/effect-of-dietary-intervention-treatment-on-children-with-iron-deficiency-anemia-in-china-a-meta-analysis
#8
Jian Sun, Lei Zhang, Jing Cui, Shanshan Li, Hongting Lu, Yong Zhang, Haiming Li, Jianping Sun, Zulqarnain Baloch
BACKGROUND: Previous studies have shown beneficial effects of dietary approaches for iron deficiency anemia (IDA) control. This study was design to investigate the effect of dietary intervention treatment on children with iron deficiency anemia. METHODS: We performed a systematic review of published dietary interventions effect on IDA treatment through meta-analysis. CBM, CNKI, Wanfang database, EMBASE, VIP, PubMed and Web of science database were searched to identify studies published between January, 1980 and December, 2016...
May 10, 2018: Lipids in Health and Disease
https://www.readbyqxmd.com/read/29746746/prevalence-of-anemia-and-consumption-of-iron-rich-food-groups-in-mexican-children-and-adolescents-ensanut-mc-2016
#9
Vanessa De la Cruz-Góngora, Salvador Villalpando, Teresa Shamah-Levy
OBJECTIVE: To describe the prevalence of anemia and con-sumption of iron rich groups among Mexican children and adolescents who participated in the Halfway National Health and Nutrition Survey, 2016. MATERIALS AND METHODS: Our study sample included children and adolescents who provided full capillary hemoglobin data. Anemia was defined accord-ing to WHO criteria. Logistic regression models were used to explore the association among consumption of iron-rich food groups, sociodemographic characteristics and anemia...
May 2018: Salud Pública de México
https://www.readbyqxmd.com/read/29729108/high-prevalence-of-anemia-in-10-month-old-japanese-infants-with-breastfeeding
#10
Masahiko Kimura, Youichi Kurozawa, Yumi Saito, Hiroshi Watanabe, Ayame Kobayashi, Takeshi Taketani
BACKGROUND: Anemia in infancy is still prevalent in developing countries. Commercial iron-fortified complementary foods or iron drops are not available in Japan and breastfed infants have a higher risk of anemia. We studied anemia screening in infants in 10-month old infants and evaluated whether breastfeeding is a risk factor for anemia. METHODS: Anemia screening was performed during a regular health check of 10-month children at four local pediatric clinics in Shimane prefecture, Japan...
May 5, 2018: Pediatrics International: Official Journal of the Japan Pediatric Society
https://www.readbyqxmd.com/read/29694583/food-and-nutrition-insecurity-indicators-associated-with-iron-deficiency-anemia-in-brazilian-children-a-systematic-review
#11
Hercilio Paulino André, Naiara Sperandio, Renata Lopes de Siqueira, Sylvia do Carmo Castro Franceschini, Silvia Eloiza Priore
This study aimed to review food and nutrition insecurity indicators associated with iron deficiency anemia in Brazilian children below 5 years. We searched in electronic databases (SciELO, Lilacs, and Medline) and selected studies by titles, abstracts and full-text reading. Of the 1,023 studies analyzed, 11 fit the inclusion criteria. The results of the studies evidenced that iron deficiency anemia in Brazilian children was associated with sociodemographic and health indicators (male, age below 24 months, children of adolescent mothers, respiratory infections, diarrhea, low maternal schooling, parents' working conditions, nursery time, lack of basic sanitation, maternal anemia, lack of ferrous sulfate use by the mother and/or child and late onset of prenatal care), nutritional indicators (low birth weight, diet characteristics, such as the habit of milk consumption close to meals, low exclusive and full breastfeeding time) and economic indicators (low per capita income)...
April 2018: Ciência & Saúde Coletiva
https://www.readbyqxmd.com/read/29693403/second-national-integrated-micronutrient-survey-in-iran-study-design-and-preliminary-findings
#12
Hamed Pouraram, Abolghasem Djazayery, Kazem Mohammad, Mahboobeh Parsaeian, Zahra Abdollahi, Ahmadreza Dorosty Motlagh, Mahmoud Djalali, Katayoon Khodaverdian, Gity Sotoudeh, Amirhusein Yarparvar, Ramin Heshmat, Fereydoun Siassi
BACKGROUND: The main objective of the Second National Integrated Micronutrient Survey (NIMS-II) was to assess the nutritional status of four micronutrients, namely iron, zinc, and vitamins A and D, and also to conduct an anthropometric assessment of selected groups of children, adolescents, pregnant women, and adults, disaggregated by sex and residential area in nationally representative samples. This paper reports the design of the study along with preliminary findings. METHODS: In this study, 32 770 individuals were selected by using single-stage cluster sampling...
April 1, 2018: Archives of Iranian Medicine
https://www.readbyqxmd.com/read/29683951/respiratory-distress-and-severe-anemia-in-a-child-with-idiopathic-pulmonary-hemosiderosis
#13
Münevver T Temel, Levent Temel, Mehmet E Coskun, Bugra T Konduk, Sinan Akbayram, Abdullah T Demiryürek
Idiopathic pulmonary hemosiderosis is an infrequent cause of pulmonary hemorrhage in children. It is classically defined by the triad of recurrent hemoptysis, iron-deficiency anemia, and diffuse parenchymal infiltration without an obvious cause. The pathogenesis remains unexplained, diagnosis may be difficult, and the clinical course exceedingly variable. A 4-year-old girl was admitted to the hospital with complaints of dyspnea, and skin and mucous membrane pallor. The suspicion of idiopathic pulmonary hemosiderosis led to the use of corticosteroid therapy with rapid improvement in clinical condition and discharge from hospital...
April 20, 2018: Journal of Pediatric Hematology/oncology
https://www.readbyqxmd.com/read/29668982/improved-medical-treatment-and-surgical-surveillance-of-children-and-adolescents-with-ulcerative-colitis-in-the-united-kingdom
#14
Marcus Karl-Keinz Auth, Su K Bunn, Aimee Leanne Protheroe, Linda Jane Williams, John M Fell, Rafeeq Muhammed, Nicholas Michael Croft, R Mark Beattie, Anne Willmott, Christine Spray, Babu Vadamalayan, Astor Rodrigues, John Puntis, Anna Jane Pigott, David C Wilson, Sally Mitton, Mark Furman, Charlie Charlton, Sonny K F Chong, Richard K Russell
Background: Pediatric ulcerative colitis (UC) presents at an earlier age and increasing prevalence. Our aim was to examine morbidity, steroid sparing strategies, and surgical outcome in children with active UC. Methods: A national prospective audit was conducted for the inpatient period of all children with UC for medical or surgical treatment in the United Kingdom (UK) over 1 year. Thirty-two participating centers recruited 224 children in 298 admissions, comparisons over 6 years were made with previous audits...
April 13, 2018: Inflammatory Bowel Diseases
https://www.readbyqxmd.com/read/29666917/measurement-of-iron-status-in-chronic-kidney-disease
#15
Wesley Hayes
Anemia is a common complication of chronic kidney disease (CKD) in children, and dysregulation of iron homeostasis plays a central role in its pathogenesis. Optimizing iron status is a prerequisite for effective treatment of anemia. Insufficient iron can lead to inappropriate escalation of the erythropoiesis-stimulating agent (ESA) dose, which is associated with adverse outcomes. Excess iron supplementation also has negative sequelae including free radical tissue damage and increased risk of systemic infection...
April 17, 2018: Pediatric Nephrology: Journal of the International Pediatric Nephrology Association
https://www.readbyqxmd.com/read/29666035/anemia-and-its-effect-on-cardiovascular-findings-in-obese-adolescents
#16
Öner Yıldırım, Tülay Demircan, Özlem Tüfekçi, Özgür Kızılca, Pınar Kuyum, Mustafa Kır, Ayhan Abacı, Nurettin Ünal, Nur Arslan, Ece Böber, Şebnem Yılmaz, Hale Ören
OBJECTIVE: We assessed the effect of anemia on cardiovascular findings in obese adolescents. MATERIALS AND METHODS: We studied 29 anemic, 33 nonanemic obese adolescents, and 33 nonobese healthy adolescents. These three groups were investigated for clinical and laboratory features of anemia and obesity. Echocardiography was used to examine cardiac functions. RESULTS: The anemia was mild (mean hemoglobin 11.67±0.79g/dL), ferritin level was significantly low, and CRP and fibrinogen levels were significantly high in anemic obese patients...
April 18, 2018: Turkish Journal of Haematology: Official Journal of Turkish Society of Haematology
https://www.readbyqxmd.com/read/29614986/rapunzel-syndrome-an-infrequent-cause-of-severe-iron-deficiency-anemia-and-abdominal-pain-presenting-to-the-pediatric-emergency-department
#17
Giuseppe Cannalire, Luigi Conti, Maurizio Celoni, Carmine Grassi, Andrea Cella, Giulia Bensi, Patrizio Capelli, Giacomo Biasucci
BACKGROUND: Iron deficiency anemia (IDA) and abdominal pain are commonly seen in a pediatric emergency department (8 and 18% incidence respectively in our center). They are manifestations of a wide variety of diseases ranging from benign to immediately life-threatening. Trichobezoar is an under-diagnosed entity that has to be considered in children and adolescents, expecially female, suffering from trichotillomania (compulsion to pull hair) and trichophagy (compulsion to swallow hair)...
April 4, 2018: BMC Pediatrics
https://www.readbyqxmd.com/read/29608808/an-unusual-cause-of-gastrointestinal-bleeding-in-a-hemodialysis-patient
#18
Julien Aron, Aymeric Couturier, Leila Sinayoko, Viviane Duedal, Christophe Ridel, Maxime Touzot
Iron deficiency caused by gastrointestinal (GI) bleeding is a common cause of anemia in hemodialysis patient. Herein, we report the case of an 89-year-old hemodialysis patient who presented with acute anemia and melena. Endoscopy found gastritis and diverticulosis without active bleeding. A capsule endoscopy (CE) was then performed and revealed multiple vascular lesions that lead to the diagnosis of Blue Rubber Bleb Nevus syndrome (BRBNS). This rare disease is associated with multiple venous malformations in the skin and the GI tract, usually observed in children...
April 2, 2018: Hemodialysis International
https://www.readbyqxmd.com/read/29601434/pediatric-collagenous-gastritis-and-colitis-a-case-series-and-review-of-the-literature
#19
Judy Matta, George Alex, Donald J S Cameron, Chung W Chow, Winita Hardikar, Ralf G Heine
INTRODUCTION: Collagenous gastritis is a rare disease characterized by the subepithelial deposition of collagen bands. Two phenotypes of the disease have been described: a pediatric-onset and an adult-onset type. The adult-onset form is associated with collagenous colitis and autoimmune disorders. No effective treatment has been identified to date. OBJECTIVE: We aim to describe the clinical features and outcomes of patients in our cohort and provide a summary of published pediatric cases with collagenous gastritis and colitis reported to date to gather information that will contribute to improved knowledge of this rare condition...
March 29, 2018: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/29568649/relation-of-food-insecurity-and-hemoglobin-level-in-preschool-aged-children
#20
Élida Mara Braga Rocha, Luiz Carlos de Abreu, Amanda Forster Lopes, Claudio Leone, Patrícia Dore Vieira, Italla Maria Pinheiro Bezerra, Sophia Cornbluth Szarfarc
Background: The iron deficiency anemia is a worldwide public problem, especially in developing countries, related to increased body needs and inadequate supply of iron from the diet. Objective: To analyze the association of food insecurity with hemoglobin concentration and the prevalence of anemia in preschool aged children in the city of Taubaté, São Paulo, Brazil. Methods: A cross-sectional study was conducted with 306 children of preschool age...
2018: Anemia
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