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Iron and anemia and children

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https://www.readbyqxmd.com/read/28068960/nutritional-status-among-primary-school-children-in-rural-sri-lanka-a-public-health-challenge-for-a-country-with-high-child-health-standards
#1
N P G C R Naotunna, M Dayarathna, H Maheshi, G S Amarasinghe, V S Kithmini, M Rathnayaka, L Premachandra, N Premarathna, P C Rajasinghe, G Wijewardana, T C Agampodi, S B Agampodi
BACKGROUND: Nutritional status of pre adolescent children is not widely studied in Sri Lanka. The purpose of this study was to determine the nutritional status among pre-adolescent school children in a rural province of Sri Lanka. METHODS: A school based cross sectional study was carried out in North Central Province in 100 rural schools, selected using multi stage cluster sampling with probability proportionate to size. Children in grade one to five were enrolled with a maximum cluster size of fifty...
January 10, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28060688/prevalence-and-risk-factors-for-iron-deficiency-anemia-and-iron-depletion-during-pregnancy-a-prospective-study
#2
Ana Gomes da Costa, Sara Vargas, Nuno Clode, Luís M Graça
INTRODUCTION: Anemia and iron deficiency during pregnancy are a worldwide concern and are more frequent among women of reproductive age, pregnant women, and young children. The aim of this study was to assess the prevalence of iron deficiency anemia and the risk factors for iron depletion during the first half of pregnancy, in a Portuguese population. MATERIAL AND METHODS: A prospective study was conducted at a tertiary hospital and included pregnant women, until the 20th week of gestation...
September 2016: Acta Médica Portuguesa
https://www.readbyqxmd.com/read/28028297/histopathological-features-of-coeliac-disease-in-a-sample-of-sudanese-patients
#3
M A N Mokhtar, S O Mekki, H M Y Mudawi, S H Sulaiman, M A Tahir, M A Tigani, I A Omer, B M Yousif, I A Fragalla, Z Mohammed, M Dafaalla
INTRODUCTION: Coeliac disease can occur at any age but is more common in children. Its diagnosis requires correlation between clinical presentations, serological results, endoscopic findings and histopathological classification using the modified Marsh grading system. This study of coeliac disease with biopsies received in the department of histopathology at Soba University Hospital, and Fedail Hospital aimed to gain insight into the demographic profile, clinical presentations and histopathological classification of patients with coeliac disease...
December 2016: Malaysian Journal of Pathology
https://www.readbyqxmd.com/read/28004477/revisiting-autoimmune-gastritis-in-children-and-adolescents-with-type-1-diabetes
#4
Alix Besançon, Bénédicte Michaud, Jacques Beltrand, Tania Goncalves, Jean-Philippe Jais, Michel Polak, Lucienne Chatenoud, Jean-Jacques Robert
OBJECTIVE: Assess the frequency of anti-H(+) /K(+) adenosine triphosphatase (ATPase) autoantibodies (AAB) and symptoms of autoimmune gastritis in children and adolescents with type 1 diabetes (T1D). RESEARCH DESIGN AND METHODS: Anti-H(+) /K(+) ATPase AAB were measured in 402 children and adolescents (210 boys and 192 girls, 11.1 ± 4.5 years) treated for T1D (screened positive for β-cell AAB), along with search of symptoms of anemia (hemoglobin, serum iron, and ferritin levels) and gastric pain...
December 22, 2016: Pediatric Diabetes
https://www.readbyqxmd.com/read/27999949/anemia-in-nephrotic-syndrome-approach-to-evaluation-and-treatment
#5
Franca Iorember, Diego Aviles
Nephrotic syndrome is one of the most common glomerular diseases that affect in children. Complications may occur in nephrotic syndrome as a result of the disease itself as well as its treatment. Most of these complications result from excessive urinary protein losses, and control of proteinuria is the most effective treatment strategy. Anemia is one of the many complications seen in patients with persistent nephrotic syndrome and may occur as a result of excessive urinary losses of iron, transferrin, erythropoietin, transcobalamin and/or metals...
December 21, 2016: Pediatric Nephrology: Journal of the International Pediatric Nephrology Association
https://www.readbyqxmd.com/read/27998390/cut-off-values-of-diagnostic-indices-to-detect-iron-deficiency-in-chinese-breast-fed-infants
#6
Qin Wu, Jie Ren, Li Chen Yang, Jie Liu, Jun Wei, Wei Zhang, Na Li, Yue Jiao Wang, Li Huang Yan, Jian Rong Ma, Xiao Guang Yang
Iron deficiency anemia is one of the most prevalent nutritional deficiency worldwide. The commonly used cut-off values for identifying iron deficiency are extrapolated from older children and may not be suitable for infants. Therefore, our study aimed to establish appropriate cut-off values for the evaluation of iron status in Chinese infants. Pregnant women who delivered at ⋝37 gestational weeks with normal iron status were recruited. Later, infants with normal birth weight and who were breastfed in the first 4 months were selected...
November 2016: Biomedical and Environmental Sciences: BES
https://www.readbyqxmd.com/read/27982368/nutrition-situation-in-latin-america-and-the-caribbean-current-scenario-past-trends-and-data-gaps
#7
Luis Galicia, Rubén Grajeda, Daniel López de Romaña
Objective: To determine the current nutritional status in Latin America and the Caribbean (LAC) and identify data gaps and trends in nutrition surveillance. Methods: A systematic Internet search was conducted to identify official sources that allowed for monitoring of LAC countries' nutritional status, including progress toward World Health Organization Global Nutrition Targets 2025. Reports from national nutrition surveillance systems and reports on nationally representative surveys were collected and collated to 1) analyze nutritional status, based on life-course anthropometric indicators and biomarkers, and 2) identify gaps in data availability and trends in nutritional deficiencies...
August 2016: Revista Panamericana de Salud Pública, Pan American Journal of Public Health
https://www.readbyqxmd.com/read/27940685/prenatal-iron-deficiency-neonatal-ferritin-and-infant-cognitive-function
#8
Michael O Mireku, Leslie L Davidson, Michael J Boivin, Romeo Zoumenou, Achille Massougbodji, Michel Cot, Florence Bodeau-Livinec
OBJECTIVE: To investigate the impact of prenatal maternal iron deficiency (ID) on cord blood serum ferritin (CBSF) concentration and infant cognitive and motor development. METHODS: Our prospective cohort study included 636 mother-singleton child pairs from 828 eligible pregnant women who were enrolled during their first antenatal care (ANC) visit in Allada, Benin, into a clinical trial comparing the efficacy of mefloquine and sulfadoxine-pyrimethamine. Venous blood samples of women were assessed for ferritin and hemoglobin concentrations at the first and second ANC visits (occurring at least 1-month apart) and at delivery...
December 2016: Pediatrics
https://www.readbyqxmd.com/read/27928530/prevalence-of-thalassemia-trait-iron-deficiency-anemia-during-infancy-in-2011-2013-in-a-thalassemia-prevalent-region-north-cyprus
#9
Burçin Şanlidağ, Buse Çağin, Övgü Özenli, Özlem Şahaloğlu, Ceyhun Dalkan, Nilüfer Galip, Arzu Babayiğit Hocaoğlu, Nerin Bahçeciler
BACKGROUND: Iron Deficiency Anemia (IDA) is an important health problem all around the world especially in developing countries. In the Mediterranean countries another prevelant reason of anemia is Thalassemia. Certain strategies had been established as a government policy to reduce prevalence in North Cyprus, such as pre-marital screening of Thalassemia. The prevalence of thalassemia trait has not been evaluated since then. The aim of this study was to detect the prevalence of IDA, thalassemia trait in infants under regular follow-up and to evaluate the compliance to prophylactic iron supplementation (PIS) and its effect on IDA...
August 2016: Iranian Journal of Public Health
https://www.readbyqxmd.com/read/27916873/the-effect-of-low-dose-iron-and-zinc-intake-on-child-micronutrient-status-and-development-during-the-first-1000-days-of-life-a-systematic-review-and-meta-analysis
#10
REVIEW
Nicolai Petry, Ibironke Olofin, Erick Boy, Moira Donahue Angel, Fabian Rohner
Adequate supply of micronutrients during the first 1000 days is essential for normal development and healthy life. We aimed to investigate if interventions administering dietary doses up to the recommended nutrient intake (RNI) of iron and zinc within the window from conception to age 2 years have the potential to influence nutritional status and development of children. To address this objective, a systematic review and meta-analysis of randomized and quasi-randomized fortification, biofortification, and supplementation trials in women (pregnant and lactating) and children (6-23 months) delivering iron or zinc in doses up to the recommended nutrient intake (RNI) levels was conducted...
November 30, 2016: Nutrients
https://www.readbyqxmd.com/read/27905971/trends-causes-and-risk-factors-of-mortality-among-children-under-5-in-ethiopia-1990-2013-findings-from-the-global-burden-of-disease-study-2013
#11
Amare Deribew, Gizachew Assefa Tessema, Kebede Deribe, Yohannes Adama Melaku, Yihunie Lakew, Azmeraw T Amare, Semaw F Abera, Mesoud Mohammed, Abiy Hiruye, Efrem Teklay, Awoke Misganaw, Nicholas Kassebaum
BACKGROUND: Ethiopia has made remarkable progress in reducing child mortality over the last two decades. However, the under-5 mortality rate in Ethiopia is still higher than the under-5 mortality rates of several low- and middle-income countries (LMIC). On the other hand, the patterns and causes of child mortality have not been well investigated in Ethiopia. The objective of this study was to investigate the mortality trend, causes of death, and risk factors among children under 5 in Ethiopia during 1990-2013...
November 14, 2016: Population Health Metrics
https://www.readbyqxmd.com/read/27895843/severe-anemia-in-malawian-children
#12
Job Cj Calis, Kamija S Phiri, E Brian Faragher, Bernard J Brabin, Imelda Bates, Luis E Cuevas, Rob J de Haan, Ajib I Phiri, Pelani Malange, Mirriam Khoka, Paul Jm Hulshof, Lisette van Lieshout, Marcel Ghm Beld, Yik Y Teo, Kirk A Rockett, Anna Richardson, Dominic P Kwiatkowski, Malcolm E Molyneux, Michaël Boele van Hensbroek
BACKGROUND: Severe anemia is a major cause of sickness and death in African children, yet the causes of anemia in this population have been inadequately studied. METHODS: We conducted a case-control study of 381 preschool children with severe anemia (hemoglobin concentration, <5.0 g per deciliter) and 757 preschool children without severe anemia in urban and rural settings in Malawi. Causal factors previously associated with severe anemia were studied. The data were examined by multivariate analysis and structural equation modeling...
September 2016: Malawi Medical Journal: the Journal of Medical Association of Malawi
https://www.readbyqxmd.com/read/27893677/impact-of-iron-deficiency-anemia-on-the-function-of-the-immune-system-in-children
#13
Tamer Hasan Hassan, Mohamed Ahmed Badr, Nehad Ahmed Karam, Marwa Zkaria, Hosam Fathy El Saadany, Doaa Mohamed Abdel Rahman, Doaa Abdallah Shahbah, Salah Mohamed Al Morshedy, Manar Fathy, Asmaa Mohamed Hosni Esh, Amal Mohamed Selim
The importance of iron deficiency as a public health problem is based ultimately on the seriousness of its consequences on health. The most extensively investigated consequences of iron deficiency involve work performance and immune function. The significance of the effects on work performance is generally accepted. In contrast, data on the influence of iron deficiency on immune function are often perceived as being confusing and contradictory.We aimed to evaluate the effect of iron deficiency anemia on humoral, cellular, nonspecific immunity, and also the effect on the cytokines that are the key factors of many immunologic steps...
November 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27891309/evaluation-of-dental-and-bone-age-in-iron-deficient-anemic-children-of-south-india
#14
Vinod Kumar, Harish Haridas, Prahlad Hunsigi, Umar Farooq, Sridhar R Erugula, Kranti K R Ealla
AIMS AND OBJECTIVES: Dental and bone age is very essential for the dental practitioner in planning treatments and is an extra source of information for the pediatrician, orthopedician, and endocrinologist. There are few published data regarding collation between dental age, bone age, and chronological age in iron-deficiency anemic children. This study has been undertaken to evaluate and compare dental age, bone age, and chronological age in children with iron-deficiency anemia. MATERIALS AND METHODS: One hundred iron-deficiency anemic children were selected in the age group of 8-14 years...
September 2016: Journal of International Society of Preventive & Community Dentistry
https://www.readbyqxmd.com/read/27891065/trends-causes-and-risk-factors-of-mortality-among-children-under-5-in-ethiopia-1990-2013-findings-from-the-global-burden-of-disease-study-2013
#15
Amare Deribew, Gizachew Assefa Tessema, Kebede Deribe, Yohannes Adama Melaku, Yihunie Lakew, Azmeraw T Amare, Semaw F Abera, Mesoud Mohammed, Abiy Hiruye, Efrem Teklay, Awoke Misganaw, Nicholas Kassebaum
BACKGROUND: Ethiopia has made remarkable progress in reducing child mortality over the last two decades. However, the under-5 mortality rate in Ethiopia is still higher than the under-5 mortality rates of several low- and middle-income countries (LMIC). On the other hand, the patterns and causes of child mortality have not been well investigated in Ethiopia. The objective of this study was to investigate the mortality trend, causes of death, and risk factors among children under 5 in Ethiopia during 1990-2013...
2016: Population Health Metrics
https://www.readbyqxmd.com/read/27883199/hepcidin-detects-iron-deficiency-in-sri-lankan-adolescents-with-a-high-burden-of-hemoglobinopathy-a-diagnostic-test-accuracy-study
#16
Katherine Wray, Angela Allen, Emma Evans, Chris Fisher, Anuja Premawardhena, Lakshman Perera, Rexan Rodrigo, Gayan Goonathilaka, Lebbe Ramees, Craig Webster, Andrew E Armitage, Andrew M Prentice, David J Weatherall, Hal Drakesmith, Sant-Rayn Pasricha
Anemia affects over 800 million women and children globally. Measurement of hepcidin as an index of iron status shows promise, but its diagnostic performance where hemoglobinopathies are prevalent is unclear. We evaluated the performance of hepcidin as a diagnostic test of iron deficiency in adolescents across Sri Lanka. We selected 2273 samples from a nationally representative cross-sectional study of 7526 secondary schoolchildren across Sri Lanka and analyzed associations between hepcidin and participant characteristics, iron indices, inflammatory markers and hemoglobinopathy states...
November 24, 2016: American Journal of Hematology
https://www.readbyqxmd.com/read/27855647/albuminuria-serum-antioxidant-enzyme-levels-and-markers-of-hemolysis-and-inflammation-in-steady-state-children-with-sickle-cell-anemia
#17
Karen E Itokua, Jean Robert Makulo, François B Lepira, Michel N Aloni, Pépé M Ekulu, Ernest K Sumaili, Justine B Bukabau, Vieux M Mokoli, Augustin L Longo, François M Kajingulu, Chantal V Zinga, Yannick M Nlandu, Yannick M Engole, Pierre Z Akilimali, René M Ngiyulu, Jean Lambert Gini, Nazaire M Nseka
BACKGROUND: Oxidative stress is thought to be involved in the pathogenesis of microalbuminuria in Sickle cell anemia (SCA). Antioxidant enzymes such as glutathione peroxidase (GPx) and Cu-Zn superoxide dismutase (SOD) may play an important protective role. This study aimed to evaluate the association between albuminuria and these two antioxidant enzymes. METHODS: We consecutively recruited Steady state children aged between 2 and 18 years old with established diagnosis of homozygous SCA in two hospitals of Kinshasa/DR Congo...
November 17, 2016: BMC Nephrology
https://www.readbyqxmd.com/read/27852523/anemia-offers-stronger-protection-than-sickle-cell-trait-against-the-erythrocytic-stage-of-falciparum-malaria-and-this-protection-is-reversed-by-iron-supplementation
#18
M M Goheen, R Wegmüller, A Bah, B Darboe, E Danso, M Affara, D Gardner, J C Patel, A M Prentice, C Cerami
BACKGROUND: Iron deficiency causes long-term adverse consequences for children and is the most common nutritional deficiency worldwide. Observational studies suggest that iron deficiency anemia protects against Plasmodium falciparum malaria and several intervention trials have indicated that iron supplementation increases malaria risk through unknown mechanism(s). This poses a major challenge for health policy. We investigated how anemia inhibits blood stage malaria infection and how iron supplementation abrogates this protection...
December 2016: EBioMedicine
https://www.readbyqxmd.com/read/27849269/adherence-to-multiple-micronutrient-powders-and-associated-factors-in-children-aged-6-to-35-months-treated-in-sentinel-health-facilities-ministry-of-health-of-peru
#19
Oscar Munares-García, Guillermo Gómez-Guizado
Introduction: Anemia in children is a public health issue, and the current strategies include treatment and iron supplementation, but their level of adherence or compliance is unknown. Objective: To consider the adherence to multiple micronutrient powders and the associated factors. Methods: Epidemiological study of active surveillance through sentinel facilities in 2,024 children aged 6 to 35 months treated in health facilities of the Ministry of Health of Peru, from October to December 2014...
July 2016: Revista Brasileira de Epidemiologia, Brazilian Journal of Epidemiology
https://www.readbyqxmd.com/read/27830928/oral-iron-absorption-test-with-ferrous-bisglycinate-chelate-in-children-with-celiac-disease-preliminary-results
#20
Giuseppe A Mazza, Luisa Pedrelli, Elisabetta Battaglia, Laura Giancotti, Roberto Miniero
BACKGROUND: Celiac disease (CD) is an immunologically-mediated enteropathy resulting in small-bowel mucosal villous atrophy with crypt hyperplasia. Iron malabsorption is usually observed in CD. Only few studies investigated oral iron absorption in subjects with gastrointestinal diseases and Iron Deficiency Anemia (IDA), using the oral iron absorption test (OIAT). We considered useful to investigate the OIAT, using Ferrous Bisglycinate Chelate (FBC), in patients with CD at diagnosis or on Gluten Free Diet (GFD) from at least 1 year...
November 10, 2016: Minerva Pediatrica
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