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Iron and anemia and children

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https://www.readbyqxmd.com/read/28934988/iron-deficiency-parameters-in-autism-spectrum-disorder-clinical-correlates-and-associated-factors
#1
Serkan Gunes, Ozalp Ekinci, Tanju Celik
BACKGROUND: High prevalence of iron deficiency (ID) and iron deficiency anemia (IDA) has been reported in children with autism spectrum disorder (ASD). However, there is a limited number of studies about the association between iron deficiency parameters and clinical symptoms of ASD. This study aims to compare hemoglobin, hematocrit, iron, ferritin, MCV, and RDW levels between ASD patients and healthy controls and to investigate the correlation between these values and clinical symptoms of ASD...
September 21, 2017: Italian Journal of Pediatrics
https://www.readbyqxmd.com/read/28923041/lay-health-workers-perceptions-of-an-anemia-control-intervention-in-karnataka-india-a-qualitative-study
#2
Arun S Shet, Abha Rao, Paul Jebaraj, Maya Mascarenhas, Merrick Zwarenstein, Maria Rosaria Galanti, Salla Atkins
BACKGROUND: Lay health workers (LHWs) are increasingly used to complement health services internationally. Their perceptions of the interventions they implement and their experiences in delivering community based interventions in India have been infrequently studied. We developed a novel LHW led intervention to improve anemia cure rates in rural community dwelling children attending village day care centers in South India. Since the intervention is delivered by the village day care center LHW, we sought to understand participating LHWs' acceptance of and perspectives regarding the intervention, particularly in relation to factors affecting daily implementation...
September 18, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28904112/modeling-the-impact-of-nutrition-interventions-on-birth-outcomes-in-the-lives-saved-tool-list
#3
REVIEW
Rebecca Heidkamp, Adrienne Clermont, Erica Phillips
Background: Negative birth outcomes [small-for-gestational age (SGA) and preterm birth (PTB)] are common in low- and middle-income countries and have important subsequent health and developmental impacts on children. There are numerous nutritional and non-nutritional interventions that can decrease the risk of negative birth outcomes and reduce subsequent risk of mortality and growth faltering.Objective: The objective of this article was to review the current evidence for the impact of nutritional interventions in pregnancy [calcium supplementation, iron and folic acid supplementation, multiple micronutrient (MMN) supplementation, and balanced energy supplementation (BES)] and risk factors (maternal anemia) on birth outcomes, with the specific goal of determining which intervention-outcome linkages should be included in the Lives Saved Tool (LiST) software...
September 13, 2017: Journal of Nutrition
https://www.readbyqxmd.com/read/28898272/iron-deficiency-was-not-the-major-cause-of-anemia-in-rural-women-of-reproductive-age-in-sidama-zone-southern-ethiopia-a-cross-sectional-study
#4
Tafere Gebreegziabher, Barbara J Stoecker
BACKGROUND: Anemia, which has many etiologies, is a moderate/severe public health problem in young children and women of reproductive age in many developing countries. The aim of this study was to investigate prevalence of iron deficiency, anemia, and iron deficiency anemia using multiple biomarkers and to evaluate their association with food insecurity and food consumption patterns in non-pregnant women from a rural area of southern Ethiopia. METHODS: A cross-sectional study was conducted in 202 rural women of reproductive age in southern Ethiopia...
2017: PloS One
https://www.readbyqxmd.com/read/28894565/hematological-characteristics-of-yemeni-adults-and-children-with-visceral-leishmaniasis-could-eosinopenia-be-a-suspicion-index
#5
Jameel Al-Ghazaly, Waled Al-Dubai, Munasser Abdullah, Leila Al-Gharasi
BACKGROUND AND OBJECTIVES: Delay in the diagnosis of visceral leishmaniasis (VL) particularly in non-endemic areas is associated with higher mortality. In our experience, we found that marked bone marrow eosinopenia was a very frequent accompaniment of VL and might be a useful clue for the diagnosis, which indicates the opportunity for further morphological assessment. The aim of this study was to describe the hematological characteristics including peripheral blood and bone marrow findings of Yemeni adults and children with VL...
2017: Mediterranean Journal of Hematology and Infectious Diseases
https://www.readbyqxmd.com/read/28874768/a-new-red-cell-index-and-portable-rbc-analyzer-for-screening-of-iron-deficiency-and-thalassemia-minor-in-a-chinese-population
#6
Lieshu Tong, Josef Kauer, Sebastian Wachsmann-Hogiu, Kaiqin Chu, Hu Dou, Zachary J Smith
Anemia is a widespread public health problem with 1/4 ~1/3 of the world's population being affected. In Southeast Asia, Thalassemia trait (TT) and iron deficiency anemia (IDA) are the two most common anemia types and can have a serious impact on quality of life. IDA patients can be treated with iron supplementation, yet TT patients have diminished capacity to process iron. Therefore, distinguishing between types of anemia is essential for effective diagnosis and treatment. Here, we present two advances towards low-cost screening for anemia...
September 5, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28870241/intestinal-helminthic-infection-and-anemia-among-pregnant-women-attending-ante-natal-care-anc-in-east-wollega-oromia-ethiopia
#7
Hylemariam Mihiretie Mengist, Olifan Zewdie, Adugna Belew
BACKGROUND: Ethiopia is a developing country where intestinal helminthic infections are major public health problems. The burden of intestinal parasites, particularly the soil-transmitted helminths (STHs), is often very high in school children and pregnant women. Anemia, associated with STH, is a major factor in women's health, especially during pregnancy; it is an important contributor to maternal mortality. The aim of this study was to determine the prevalence of intestinal helminthic infection and anemia among pregnant women attending ANC in East Wollega Zone, Ethiopia...
September 5, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28854239/helicobacter-pylori-saba-gene-is-associated-with-iron-deficiency-anemia-in-childhood-and-adolescence
#8
Seiichi Kato, Takako Osaki, Shigeru Kamiya, Xue-Song Zhang, Martin J Blaser
BACKGROUND: Gastric Helicobacter pylori colonization leads to iron deficiency anemia (IDA), especially in children and adolescents. However the pathogenesis is poorly understood. OBJECTIVE: We sought to identify specific H. pylori genes involved in IDA development, by comparing bacterial genome-wide expression profiling in patients affected or not. METHODS: H. pylori were isolated from four children with IDA and four from matched controls without IDA...
2017: PloS One
https://www.readbyqxmd.com/read/28852503/lower-incidence-of-respiratory-infections-among-iron-deficient-children-in-kilimanjaro-tanzania
#9
Katherine Wander, Bettina Shell-Duncan, Eleanor Brindle
Objective: We posited a trade-off in iron nutrition, with iron deficiency decreasing risk for infection by depriving infectious agents of iron while increasing risk for infection by compromising immune protection. We described associations between iron deficiency and prevalent and incident infectious disease episodes and cell-mediated immunity (CMI) among 283 children in Kilimanjaro, Tanzania. Methodology: Whole blood specimens were evaluated for hemoglobin and dried blood spots (DBS) were evaluated for biomarkers of iron deficiency (transferrin receptor) and inflammation (C-reactive protein and α1-acid glycoprotein)...
2017: Evolution, Medicine, and Public Health
https://www.readbyqxmd.com/read/28831808/reply-intravenous-ferumoxytol-in-pediatric-patients-with-iron-deficiency-anemia
#10
Nabil E Hassan
Iron Deficiency in children is common problem. Its mechanism could be nutritional or due to lack of iron absorption. Several conditions are associated with IDA. Presence of inflammation further complicate attempts to make a definitive diagnoses or accurately quantify reponse to therapy.
August 1, 2017: Annals of Pharmacotherapy
https://www.readbyqxmd.com/read/28829731/high-prevalence-of-anemia-but-low-level-of-iron-deficiency-in-preschool-children-during-a-low-transmission-period-of-malaria-in-rural-kivu-democratic-republic-of-the-congo
#11
Esto Bahizire, Paluku Bahwere, Philippe Donnen, P Lundimu Tugirimana, Serge Balol'ebwami, Michèle Dramaix, Chouchou Nfundiko, Raphaël Chirimwami, Kanigula Mubagwa
Anemia is a worldwide public health concern especially in preschool children in developing countries and iron deficiency (ID) is generally assumed to cause at least 50% of the cases. However, data on this contribution are scarce. To close this gap, we determined in 2013 the contribution of ID in the etiology of anemia and measured others factors associated to noniron deficiency anemia (NIDA) in 900 preschool children randomly selected during a two-stage cluster nutritional survey in the Miti-Murhesa health zone, in eastern Democratic Republic of the Congo...
August 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28826251/prevalence-of-iron-deficiency-and-iron-deficiency-anemia-in-the-northern-and-southern-provinces-of-rwanda
#12
Moira Donahue Angel, Peter Berti, Kendra Siekmans, Pierrot Lundimu Tugirimana, Erick Boy
BACKGROUND: Anemia remains a public health problem in Rwanda, affecting 38% of young children and 17% of reproductive-aged women (Demographic and Health Survey [DHS] 2010). The importance of iron deficiency (ID) as a cause of anemia in Rwanda is not known. OBJECTIVE: We aimed to estimate the prevalence of ID and iron deficiency anemia (IDA) among young children and women in 2 provinces of Rwanda. METHODS: We conducted a cluster randomized survey, selecting 408 rural households each in the Northern and Southern Provinces of Rwanda in 2010...
January 1, 2017: Food and Nutrition Bulletin
https://www.readbyqxmd.com/read/28821470/design-of-the-drepagreffe-trial-a-prospective-controlled-multicenter-study-evaluating-the-benefit-of-genoidentical-hematopoietic-stem-cell-transplantation-over-chronic-transfusion-in-sickle-cell-anemia-children-detected-to-be-at-risk-of-stroke-by-transcranial
#13
Sylvie Chevret, Suzanne Verlhac, Elisabeth Ducros-Miralles, Jean-Hugues Dalle, Regis Peffault de Latour, Mariane de Montalembert, Malika Benkerrou, Corinne Pondarré, Isabelle Thuret, Corinne Guitton, Emmanuelle Lesprit, Maryse Etienne-Julan, Gisèle Elana, Jean-Pierre Vannier, Patrick Lutz, Bénédicte Neven, Claire Galambrun, Catherine Paillard, Camille Runel, Charlotte Jubert, Cécile Arnaud, Annie Kamdem, Valentine Brousse, Florence Missud, Marie Petras, Lydia Doumdo-Divialle, Claire Berger, Françoise Fréard, Olivier Taieb, Elise Drain, Monique Elmaleh, Manuela Vasile, Yacine Khelif, Myriam Bernaudin, Philippe Chadebech, France Pirenne, Gérard Socié, Françoise Bernaudin
BACKGROUND: Children with sickle cell anemia (SCA) have an 11% risk of stroke by the age of 18. Chronic transfusion applied in patients detected to be at risk by transcranial Doppler allows a significant reduction of stroke risk. However, chronic transfusion exposes to several adverse events, including alloimmunization and iron overload, and is not curative. Hematopoietic stem cell transplantation allows termination of the transfusion program, but its benefit has not been demonstrated...
August 15, 2017: Contemporary Clinical Trials
https://www.readbyqxmd.com/read/28814393/soya-maize-and-sorghum-based-ready-to-use-therapeutic-food-with-amino-acid-is-as-efficacious-as-the-standard-milk-and-peanut-paste-based-formulation-for-the-treatment-of-severe-acute-malnutrition-in-children-a-noninferiority-individually-randomized-controlled
#14
Paluku Bahwere, Peter Akomo, Mwawi Mwale, Hitoshi Murakami, Chrissy Banda, Sylvester Kathumba, Chimwemwe Banda, Solomon Jere, Kate Sadler, Steve Collins
Background: Development of more cost-effective ready-to-use therapeutic food (RUTF) is a global public health priority. To date, previous lower-cost recipes have been less effective than the standard peanut and milk (PM)-based RUTF, particularly in children aged <24 mo.Objective: We aimed to compare the efficacy of the PM-RUTF to a milk-free soya, maize, and sorghum (FSMS)-RUTF enriched with crystalline amino acids without cow milk powder and a milk, soya, maize, and sorghum (MSMS)-RUTF containing 9.3% skim cow milk powder...
August 16, 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28809788/correction-gupta-p-m-et-al-iron-anemia-and-iron-deficiency-anemia-among-young-children-in-the-united-states-nutrients-2016-8-330
#15
Priya M Gupta, Cria G Perrine, Zuguo Mei, Kelley S Scanlon
We would like to submit the following correction to our recently published paper [1] due to the error in classification of children as anemic [...].
August 15, 2017: Nutrients
https://www.readbyqxmd.com/read/28772256/non-syndromic-childhood-onset-congenital-sideroblastic-anemia-a-report-of-13-patients-identified-with-an-alas2-or-slc25a38-mutation
#16
Marie-Amelyne Le Rouzic, Cyrielle Fouquet, Thierry Leblanc, Mohamed Touati, Fanny Fouyssac, Christiane Vermylen, Nadja Jäkel, Jean-François Guichard, Karim Maloum, Fabienne Toutain, Patrick Lutz, Yves Perel, Hana Manceau, Caroline Kannengiesser, Jean-Pierre Vannier
The most frequent germline mutations responsible for non syndromic congenital sideroblastic anemia are identified in ALAS2 and SLC25A38 genes. Iron overload is a key issue and optimal chelation therapy should be used to limit its adverse effects on the development of children. Our multicentre retrospective descriptive study compared the strategies for diagnosis and management of congenital sideroblastic anemia during the follow-up of six patients with an ALAS2 mutation and seven patients with an SLC25A38 mutation...
July 26, 2017: Blood Cells, Molecules & Diseases
https://www.readbyqxmd.com/read/28768839/serum-soluble-transferrin-receptor-concentrations-are-elevated-in-congolese-children-with-glucose-6-phosphate-dehydrogenase-variants-but-not-sickle-cell-variants-or-%C3%AE-thalassemia
#17
Mikaela K Barker, Amanda M Henderson, Karimah Naguib, Suzanne M Vercauteren, Angela M Devlin, Arianne Y Albert, Esto Bahizire, Pierrot L Tugirimana, Pierre Z Akilimali, Erick Boy, Tim J Green, Crystal D Karakochuk
Background: Anemia is common in Congolese children, and inherited blood disorders may be a contributing cause. The presence of sickle cell variants, X-linked glucose-6-phosphate dehydrogenase (G6PD) deficiency and α-thalassemia, has been previously reported. G6PD A- deficiency is characterized by the co-inheritance of G6PD 376 and 202 variants and is common in sub-Saharan Africa.Objective: We aimed to measure the associations between inherited blood disorders and hemoglobin, ferritin, and soluble transferrin receptor (sTfR) concentrations in Congolese children...
September 2017: Journal of Nutrition
https://www.readbyqxmd.com/read/28738401/serum-vitamins-and-minerals-at-diagnosis-and-follow-up-in-children-with-celiac-disease
#18
Vini Deora, Nicole Aylward, AbdulRazaq Sokoro, Wael El-Matary
OBJECTIVES: Children with celiac disease (CD) may experience deficiencies of several micronutrients. The objectives of the present study were to determine the prevalence of micronutrient deficiencies in children with CD at diagnosis, 6 months, and 18 months after the start of a gluten-free diet (GFD), and examine any correlation between micronutrient deficiencies, serum tissue transglutaminase (TtG) immunoglobulin A (IgA) antibody titers, and the degree of mucosal damage at diagnosis...
August 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/28722565/high-iron-levels-are-associated-with-increased-malaria-risk-in-infants-during-the-first-year-of-life-in-benin
#19
Violeta Moya-Alvarez, Gilles Cottrell, Smaila Ouédraogo, Manfred Accrombessi, Achille Massougbodgi, Michel Cot
The World Health Organization (WHO) estimates that 40% of children in low-income countries are anemic. Therefore, iron supplements are recommended by WHO in areas with high anemia rates. However, some studies have set into question the benefits of iron supplementation in malaria-endemic regions. In Benin, a west African country with high prevalence of anemia and malaria, no iron supplements are given systematically to infants so far despite the WHO recommendations. In this context, we wanted to investigate the effect of iron levels during the first year of life on malarial risk in Benin considering complementary risk factors...
August 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28708072/iron-fortified-complementary-foods-containing-a-mixture-of-sodium-iron-edta-with-either-ferrous-fumarate-or-ferric-pyrophosphate-reduce-iron-deficiency-anemia-in-12-to-36-month-old-children-in-a-malaria-endemic-setting-a-secondary-analysis-of-a-cluster-randomized
#20
Dominik Glinz, Rita Wegmüller, Mamadou Ouattara, Victorine G Diakité, Grant J Aaron, Lorenz Hofer, Michael B Zimmermann, Lukas G Adiossan, Jürg Utzinger, Eliézer K N'Goran, Richard F Hurrell
Iron deficiency anemia (IDA) is a major public health problem in sub-Saharan Africa. The efficacy of iron fortification against IDA is uncertain in malaria-endemic settings. The objective of this study was to evaluate the efficacy of a complementary food (CF) fortified with sodium iron EDTA (NaFeEDTA) plus either ferrous fumarate (FeFum) or ferric pyrophosphate (FePP) to combat IDA in preschool-age children in a highly malaria endemic region. This is a secondary analysis of a nine-month cluster-randomized controlled trial conducted in south-central Côte d'Ivoire...
July 14, 2017: Nutrients
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