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https://www.readbyqxmd.com/read/28411395/a-longitudinal-study-of-smokeless-tobacco-use-and-mortality-in-the-united-states
#1
David S Timberlake, Dmitriy Nikitin, Norman J Johnson, Sean F Altekruse
Few studies in the United States have examined longitudinally the mortality risks associated with use of smokeless tobacco (SLT). The sample of our study was composed of participants from the National Longitudinal Mortality Study who completed a single Tobacco Use Supplement to the Current Population Survey between the years 1985 and 2011. Using survival methods, SLT use at the baseline survey was examined as a predictor of all-cause mortality and cause-specific mortalities in models that excluded individuals who had ever smoked cigarettes, cigars or used pipes (final n = 349,282)...
April 14, 2017: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/28379362/genetic-studies-on-the-physiological-role-of-corvet-in-aspergillus-nidulans
#2
Manuel S López-Berges, Herbert N Arst, Mario Pinar, Miguel A Peñalva
CORVET and HOPS are protein complexes mediating the maturation of early endosomes (EEs) into late endosomes (LEs)/vacuoles. These hetero-hexamers share four 'core' components, Vps11, Vps16, Vps18 and Vps33, and differ in two specific subunits, CORVET Vps8 and Vps3 and HOPS Vps39 and Vps41. Whereas ablating HOPS-specific components has minor growth effects, ablating any CORVET constituent severely debilitates Aspergillus nidulans growth, buttressing previous work indicating that maturation of EEs into LEs is physiologically crucial...
March 30, 2017: FEMS Microbiology Letters
https://www.readbyqxmd.com/read/28375697/iteration-of-partially-specified-target-matrices-application-to-the-bi-factor-case
#3
Francisco J Abad, Eduardo Garcia-Garzon, Luis E Garrido, Juan R Barrada
The current study proposes a new bi-factor rotation method, Schmid-Leiman with iterative target rotation (SLi), based on the iteration of partially specified target matrices and an initial target constructed from a Schmid-Leiman (SL) orthogonalization. SLi was expected to ameliorate some of the limitations of the previously presented SL bi-factor rotations, SL and SL with target rotation (SLt), when the factor structure either includes cross-loadings, near-zero loadings, or both. A Monte Carlo simulation was carried out to test the performance of SLi, SL, SLt, and the two analytic bi-factor rotations, bi-quartimin and bi-geomin...
April 4, 2017: Multivariate Behavioral Research
https://www.readbyqxmd.com/read/28345014/the-cigarette-and-smokeless-tobacco-markets-in-texas-relative-to-the-united-states
#4
Erin J Miller Lo, Daniel P Giovenco, Olivia A Wackowski, Melissa B Harrell, Cheryl L Perry, Cristine D Delnevo
OBJECTIVE: This study compares the cigarette and smokeless tobacco (SLT) markets in Texas and the United States (US) as a whole. METHODS: Nielsen convenience store sales data from 2014 were obtained for Dallas, Houston, San Antonio/Austin, and the total US. Descriptive statistics highlighted market share differences in Texas compared to the US overall. RESULTS: Marlboro and Copenhagen dominated the cigarette (58.9%) and SLT markets (44.8%) in Texas and had substantially higher relative market shares in Texas than nationally (46...
April 2017: Tobacco Regulatory Science
https://www.readbyqxmd.com/read/28339591/comparison-of-the-force-levels-among-labial-and-lingual-self-ligating-and-conventional-brackets-in-simulated-misaligned-teeth
#5
Ahmad Alobeid, Tarek El-Bialy, Said Khawatmi, Cornelius Dirk, Andreas Jäger, Christoph Bourauel
Background/objective: The aim of this study was to evaluate force levels exerted by levelling arch wires with labial and lingual conventional and self-ligating brackets. Materials/methods: The tested orthodontic brackets were of the 0.022-in slot size for labial and 0.018-in for lingual brackets and were as follows: 1. Labial brackets: (i) conventional bracket (GAC-Twin, Dentsply), (ii) passive self-ligating (SL) brackets (Damon-Q®, ORMCO; Ortho classic H4™, Orthoclassic; FLI®SL, Rocky Mountain Orthodontics) and (iii) active SL brackets (GAC In-Ovation®C, DENTSPLY and SPEED™, Strite)...
January 25, 2017: European Journal of Orthodontics
https://www.readbyqxmd.com/read/28306585/behaviour-change-technique-taxonomy-a-method-of-describing-head-and-neck-cancer-dysphagia-intervention-delivery
#6
Kate Toft, Helen Stringer
PURPOSE OF REVIEW: The purpose of the review is to examine the current state of the art of dysphagia intervention delivery description and to propose use of a new tool to facilitate this: the behaviour change technique taxonomy version 1 (BCTTv1). RECENT FINDINGS: Describing intervention delivery is difficult, and published research in the field of speech and language therapy (SLT) does not include detail on this key aspect of research protocols. Interventions themselves are often poorly delineated, and a way is needed of classifying how these interventions are delivered in practice...
March 16, 2017: Current Opinion in Otolaryngology & Head and Neck Surgery
https://www.readbyqxmd.com/read/28294176/salvage-liver-transplantation-leads-to-poorer-outcome-in-hepatocellular-carcinoma-compared-with-primary-liver-transplantation
#7
Yuhua Shan, Lifeng Huang, Qiang Xia
Hepatocellular carcinoma is the most common liver malignancy. Salvage liver transplantation (SLT) is viewed as a feasible cure for recurrence of HCC after resectomy, but the effect is under dispute. A retrospective study examined data at Renji Hospital for 239 transplants from January 2006 to December 2015, including 211 who received primary liver transplantation (PLT) and 28 who underwent SLT. A multivariable cox regression model was employed to pick out relative factors to overall survival (OS) and recurrence free survival (RFS)...
March 15, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28282359/locoregional-therapy-with-curative-intent-versus-primary-liver-transplant-for-hepatocellular-carcinoma-systematic-review-and-meta-analysis
#8
A R Murali, S Patil, K T Phillips, M Voigt
BACKGROUND: Loco-regional therapy with curative intent (CLRT) followed by salvage liver transplant (SLT) in case of HCC recurrence is an alternative to primary liver transplant (LT) in selected patients with HCC. METHODS: We performed a systematic review and meta-analysis of studies comparing the survival of patients treated with CLRT versus LT, stratified by the stage of liver disease, extent of cancer, and whether SLT was offered or not. RESULTS: We included 48 studies involving 9835 patients (5736 patients with CLRT and 4119 patients with primary LT)...
March 10, 2017: Transplantation
https://www.readbyqxmd.com/read/28277332/dysphagia-management-in-tracheostomized-patients-where-are-we-now
#9
Diane Goff
PURPOSE OF REVIEW: Tracheostomized patients are medically complex and vulnerable. International attention is now focused on improving the safety and quality of their care. This review summarizes recent evidence in hot-topic areas pertinent to speech and language therapy (SLT) intervention for dysphagia management in tracheostomized patients. RECENT FINDINGS: The management of tracheostomized patients requires a truly multidisciplinary team (MDT) approach. Without this, patients remain tracheostomized and hospitalized for longer and have slower access to MDT members...
March 8, 2017: Current Opinion in Otolaryngology & Head and Neck Surgery
https://www.readbyqxmd.com/read/28264102/mechanism-of-action-of-selective-laser-trabeculoplasty-and-predictors-of-response
#10
Vikas Gulati, Shan Fan, Bret J Gardner, Shane J Havens, Marie T Schaaf, Donna G Neely, Carol B Toris
Purpose: This study was designed to evaluate the changes in aqueous humor dynamics (AHD) produced by selective laser trabeculoplasty (SLT) and to explore if baseline AHD parameters are predictive of IOP response to SLT. Methods: Thirty-one consecutive subjects diagnosed with ocular hypertension or primary open-angle glaucoma scheduled to undergo SLT as their primary IOP-lowering therapy were enrolled in this prospective observational study. Subjects underwent baseline assessment of AHD in both eyes...
March 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28258400/a-review-of-selective-laser-trabeculoplasty-recent-findings-and-current-perspectives
#11
REVIEW
Yujia Zhou, Ahmad A Aref
Selective laser trabeculoplasty (SLT) has been widely used in the clinical management of glaucoma, both as primary and adjunctive treatment. As new evidence continues to arise, we review the current literature in terms of indications and efficacy, surgical technique, postoperative care, repeatability, and complications of this therapy. SLT has been shown to be effective in various glaucomas, including primary open-angle glaucoma (POAG), normal-tension glaucoma (NTG), steroid-induced glaucoma, pseudoexfoliation glaucoma (PXFG), and primary angle-closure glaucoma (PACG), as well as other glaucoma subtypes...
March 3, 2017: Ophthalmology and Therapy
https://www.readbyqxmd.com/read/28245337/feasibility-of-laser-trabeculoplasty-in-angle-closure-glaucoma-a-review-of-favourable-histopathological-findings-in-narrow-angles
#12
REVIEW
Alexis Galeno Matos, Sanjay G Asrani, Jayter Silva Paula
Selective laser trabeculoplasty (SLT) has been indicated as a safe and efficient treatment for primary open-angle glaucoma; however, recent studies have also shown positive results with the use of SLT in some clinical conditions related to primary angle-closure glaucoma (PACG). Despite the potential benefits of SLT in selected cases of PACG, the mechanisms underlying the modifications in the trabecular meshwork tissue of patients with PACG are poorly understood. This narrative review approached both the current, limited knowledge about the histological changes observed in different forms of PACG and the clinical results of SLT treatment for PACG...
February 28, 2017: Clinical & Experimental Ophthalmology
https://www.readbyqxmd.com/read/28241458/bulgecin%C3%A2-a-%C3%A2-the%C3%A2-key%C3%A2-to%C3%A2-a%C3%A2-broad-spectrum%C3%A2-inhibitor%C3%A2-that%C3%A2-targets%C3%A2-lytic%C3%A2-transglycosylases
#13
Allison H Williams, Richard Wheeler, Constance Thiriau, Ahmed Haouz, Muhamed-Kheir Taha, Ivo G Boneca
Lytic transglycosylases (Lts) are involved in recycling, cell division, and metabolism of the peptidoglycan. They have been understudied for their usefulness as potential antibacterial targets due to their high redundancy in Gram-negative bacteria. Bulgecin A is an O-sulphonated glycopeptide that targets primarily soluble lytic tranglycosylases (Slt). It has been shown that bulgecin A increases the efficacy of β-lactams that target penicillin bindings proteins (PBPs). Here, we present the high-resolution crystal structure of LtgA from Neisseria meningitidis strain MC58, a membrane bound homolog of Escherichia coli Slt, in complex with bulgecin A...
February 22, 2017: Antibiotics
https://www.readbyqxmd.com/read/28231380/perioperative-medications-for-preventing-temporarily-increased-intraocular-pressure-after-laser-trabeculoplasty
#14
REVIEW
Linda Zhang, Jennifer S Weizer, David C Musch
BACKGROUND: Glaucoma is the international leading cause of irreversible blindness. Intraocular pressure (IOP) is the only currently known modifiable risk factor; it can be reduced by medications, incisional surgery, or laser trabeculoplasty (LTP). LTP reduces IOP by 25% to 30% from baseline, but early acute IOP elevation after LTP is a common adverse effect. Most of these IOP elevations are transient, but temporarily elevated IOP may cause further optic nerve damage, worsening of glaucoma requiring additional therapy, and permanent vision loss...
February 23, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28221190/pulmonary-perfusion-changes-following-single-lung-transplantation
#15
Joby Tsai, Steven P Rowe, Lilja B Solnes, Roberto A Salas Fragomeni
Following single-lung transplantation (SLT), there is significant redistribution of flow preferentially to the transplanted lung. Altered lung perfusion leads to unusual results when performing pulmonary scintigraphy, which could result in interpretation errors. We present pulmonary scintigraphy images from a 67-year-old female patient with history of chronic obstructive pulmonary disease that were obtained before SLT, 10 days after SLT, and 3 months after SLT.
May 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/28188403/-stereotactic-laser-thermocoagulation-in-epilepsy-surgery
#16
C Hoppe, J-A Witt, C Helmstaedter, T Gasser, H Vatter, C E Elger
In common with other stereotactic procedures, stereotactic laser thermocoagulation (SLT) promises gentle destruction of pathological tissue, which might become especially relevant for epilepsy surgery in the future. Compared to standard resection, no large craniotomy is necessary, cortical damage during access to deep-seated lesions can be avoided and interventions close to eloquent brain areas become possible. We describe the history and rationale of laser neurosurgery as well as the two available SLT systems (Visualase® and NeuroBlate®; CE marks pending)...
February 10, 2017: Der Nervenarzt
https://www.readbyqxmd.com/read/28178150/the-effects-of-selective-laser-trabeculoplasty-and-travoprost-on-circadian-intraocular-pressure-fluctuations-a-randomized-clinical-trial
#17
RANDOMIZED CONTROLLED TRIAL
Weerawat Kiddee, Supreeya Atthavuttisilp
BACKGROUND: To compare the effect of selective laser trabeculoplasty (SLT) and travoprost on 24-hour IOP fluctuations in primary open-angle glaucoma (POAG) and normal-tension glaucoma (NTG). METHODS: Sixty eyes were included. Sixteen and 14 eyes of POAG patients were randomized to receive 360° SLT or 0.004% travoprost, respectively. Fourteen and 16 eyes of NTG patients were randomized to receive either SLT or travoprost, respectively. The 24-hour IOP data were collected before treatment and 6 to 8 weeks after treatment...
February 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28168045/transient-peripapillary-retinoschisis-in-glaucomatous-eyes
#18
Josine van der Schoot, Koenraad A Vermeer, Hans G Lemij
Purpose. To investigate transient focal microcystic retinoschisis in glaucomatous eyes in images obtained with several imaging techniques used in daily glaucoma care. Methods. Images of 117 glaucoma patients and 91 healthy subjects participating in a large prospective follow-up study into glaucoma imaging were reviewed. Participants were measured with spectral domain optical coherence tomography (SD-OCT), scanning laser polarimetry (SLP), scanning laser tomography (SLT), and standard automated perimetry (SAP)...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/28165214/tape-casting-of-high-performance-low-temperature-solid-oxide-cells-with-thin-la0-8sr0-2ga0-8mg0-2o3-%C3%AE-electrolytes-and-impregnated-nano-anodes
#19
Zhan Gao, Hongqian Wang, Elizabeth Miller, Qinyuan Liu, Daniel Senn, Scott Barnett
Low-temperature solid oxide cells (LT-SOCs), operating at 400 to 650 °C, have great potential for commercialization since they can provide lower cost and improved long-term durability. Low operating temperature can also enable high round-trip efficiency of SOCs as reversible energy storage devices. This paper describes Sr0.8La0.2TiO3-α (SLT) anode supported LT-SOC with thin La0.8Sr0.2Ga0.8Mg0.2O3-δ (LSGM) electrolyte made by tape casting, with screen printed La0.6Sr0.4Fe0.8Co0.2O3-δ (LSCF) cathode and impregnated Ni anode...
March 1, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28160661/measuring-youth-beliefs-about-the-harms-of-e-cigarettes-and-smokeless-tobacco-compared-to-cigarettes
#20
Alexander Persoskie, Erin Keely O'Brien, Anh B Nguyen, Cindy Tworek
This study examined validity of direct and indirect measures of perceived harm of e-cigarettes and smokeless tobacco (SLT) compared to cigarettes. On direct measures, people compare one product to another, whereas on indirect measures, people rate each product separately and the researcher compares these ratings. Data from youth in Wave 1 of the Population Assessment of Tobacco and Health (PATH) Study (2013-2014) were analyzed (N=13,651 youth aged 12-17years). The study included direct measures of perceived harm of e-cigarettes and SLT compared to cigarettes, and indirect measures were created by comparing ratings of the products...
July 2017: Addictive Behaviors
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