Avika Ruparell, Janet E Alexander, Ryan Eyre, Laura Carvell-Miller, Y Becca Leung, Samantha J M Evans, Lucy J Holcombe, Martina Heer, Phillip Watson
Intracellular levels of glutathione, the major mammalian antioxidant, are reported to decline with age in several species. To understand whether ageing affects circulating glutathione levels in cats, blood was sampled from two age groups, < 3 years and > 9 years. Further, to determine whether dietary supplementation with glutathione precursor glycine (GLY) affects glutathione concentrations in senior cats (> 9 years), a series of free GLY inclusion level dry diets were fed. Subsequently, a 16-week GLY feeding study was conducted in senior cats (age), measuring glutathione, and markers of oxidative stress...
February 29, 2024: British Journal of Nutrition