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Colorectal obstruction

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https://www.readbyqxmd.com/read/27900043/second-look-surgery-following-hartmann-s-procedure-for-obstructive-left-sided-colorectal-cancer
#1
Naohito Beppu, Fumihiko Kimura, Nagahide Matsubara, Masashi Noda, Naohiro Tomita, Hidenori Yanagi, Naoki Yamanaka
The aim of the present study was to investigate the short- and long-term outcomes of patients undergoing second-look surgery following Hartmann's procedure for obstructive left-sided colorectal cancer (LSCC). All patients included in the present study had undergone radical surgery with Hartmann's procedure for obstructive LSCC. Adjuvant chemotherapy was recommended for all patients, and patients with no signs of recurrence following six months of surveillance were planned to undergo second-look surgery. The aim of second-look surgery was early detection of local recurrence and determination of the efficacy of laparoscopic Hartmann procedure reversal...
November 2016: Oncology Letters
https://www.readbyqxmd.com/read/27853888/delay-of-surgery-after-stent-placement-for-resectable-malignant-colorectal-obstruction-is-associated-with-higher-risk-of-recurrence
#2
Malene Broholm, Martin Kobborg, Erik Frostberg, Maja Jeppesen, Ismail Gögenür
BACKGROUND: Self-expanding metal stents can be used as bridge to elective surgery for acute malignant colonic obstruction. However, the impact on long-term oncological outcome and the optimal timing of surgery are still unknown. METHOD: This was a retrospective multicenter study performed at four colorectal centers. Patients undergoing stent placement as bridge to surgery, between January 2010 and December 2013, were included in the study. Primary outcomes were survival and recurrence rates along with location of the metastases...
November 16, 2016: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/27834916/systematic-analysis-of-protein-interaction-network-associated-with-azoospermia
#3
Soudabeh Sabetian, Mohd Shahir Shamsir
Non-obstructive azoospermia is a severe infertility factor. Currently, the etiology of this condition remains elusive with several possible molecular pathway disruptions identified in the post-meiotic spermatozoa. In the presented study, in order to identify all possible candidate genes associated with azoospermia and to map their relationship, we present the first protein-protein interaction network related to azoospermia and analyze the complex effects of the related genes systematically. Using Online Mendelian Inheritance in Man, the Human Protein Reference Database and Cytoscape, we created a novel network consisting of 209 protein nodes and 737 interactions...
November 10, 2016: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/27833380/indications-and-surgical-options-for-small-bowel-large-bowel-and-perianal-crohn-s-disease
#4
REVIEW
James Wt Toh, Peter Stewart, Matthew Jfx Rickard, Rupert Leong, Nelson Wang, Christopher J Young
Despite advancements in medical therapy of Crohn's disease (CD), majority of patients with CD will eventually require surgical intervention, with at least a third of patients requiring multiple surgeries. It is important to understand the role and timing of surgery, with the goals of therapy to reduce the need for surgery without increasing the odds of emergency surgery and its associated morbidity, as well as to limit surgical recurrence and avoid intestinal failure. The profile of CD patients requiring surgical intervention has changed over the decades with improvements in medical therapy with immunomodulators and biological agents...
October 28, 2016: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/27830519/postoperative-mortality-and-morbidity-in-older-patients-undergoing-emergency-right-hemicolectomy-for-colon-cancer
#5
Renata Tabola, George Mantese, Roberto Cirocchi, Alessandro Gemini, Veronica Grassi, Carlo Boselli, Stefano Avenia, Alessandro Sanguinetti, Nicola Avenia, Maciej Sroczynski, Jaroslaw Wierzbicki
INTRODUCTION: Even with the advances in surgical technique and perioperative care, morbidity and mortality after colorectal cancer surgery remain considerable, and patients (pt) who present as an emergency have an even higher mortality and morbidity rate. METHODS: A total of 35 pt with caecum or ascending colon cancer between January 2007 and June 2015, three departments in Italy and in Poland, were included in the study. The intention of surgery in all cases was curative resection with ileo-colic anastomosis...
November 9, 2016: Aging Clinical and Experimental Research
https://www.readbyqxmd.com/read/27822263/focal-sinusoidal-obstruction-syndrome-caused-by-oxaliplatin-induced-chemotherapy-a-case-report
#6
Takaharu Kawai, Shintaro Yamazaki, Atsuko Iwama, Tokio Higaki, Masahiko Sugitani, Tadatoshi Takayama
INTRODUCTION: Sinusoidal obstruction syndrome (SOS) is a severe adverse event of long-term chemotherapy in patients with colorectal cancer. It usually develops as liver congestion due to diffuse microscopic obstruction in liver parenchyma. In contrast, it sometimes appears as a liver mass occurring with local parenchymal hemorrhaging, and is often misdiagnosed as liver metastasis. CASE PRESENTATION: A 40-year-old woman with rectal cancer underwent high anterior resection and partial liver resection of segment 7 due to synchronous liver metastasis...
September 2016: Hepatitis Monthly
https://www.readbyqxmd.com/read/27817034/predictors-of-outcome-for-endoscopic-colorectal-stenting-a-decade-experience
#7
Maher A Abbas, Greg Kharabadze, Ethan M Ross, Mohammad A Abbass
PURPOSE: Endoscopic stenting is used with increasing frequency to treat colorectal conditions. Little is known about what influences outcome. This study aimed to determine the impact of various factors on the short- and long-term results of colorectal stenting. METHODS: A retrospective review was conducted of all endoscopic stenting procedures performed by a colorectal surgeon at a tertiary referral institution between 2003 and 2013. Main outcome measures included technical success, clinical success, complications, and predictors of outcome...
November 5, 2016: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/27815722/disappearing-or-residual-tiny-%C3%A2-5%C3%A2-mm-colorectal-liver-metastases-after-chemotherapy-on-gadoxetic-acid-enhanced-liver-mri-and-diffusion-weighted-imaging-is-local-treatment-required
#8
Seung Soo Kim, Kyoung Doo Song, Young Kon Kim, Hee Cheol Kim, Jung Wook Huh, Young Suk Park, Joon Oh Park, Seung Tae Kim
OBJECTIVES: To evaluate the clinical course of disappearing colorectal liver metastases (DLM) or residual tiny (≤5 mm) colorectal liver metastases (RTCLM) on gadoxetic acid-enhanced magnetic resonance imaging (MRI) and diffusion-weighted imaging (DWI) in patients who had colorectal liver metastases (CLM) and received chemotherapy. METHODS: Among 137 patients who received chemotherapy for CLM and underwent gadoxetic acid-enhanced MRI and DWI between 2010 and 2012, 43 patients with 168 DLMs and 48 RTCLMs were included...
November 4, 2016: European Radiology
https://www.readbyqxmd.com/read/27797992/impact-of-referral-templates-on-patient-experience-of-the-referral-and-care-process-a-cluster-randomised-trial
#9
Henrik Wåhlberg, Tonje Braaten, Ann Ragnhild Broderstad
OBJECTIVES: To evaluate if a referral intervention improves the patient experience of the referral and treatment process. SETTING: Interface between 14 primary care surgeries and a district general hospital. PARTICIPANTS: The 14 general practitioner (GP) surgeries (7 intervention, 7 control) in the area around the University Hospital of North Norway Harstad were randomised and all completed the study. Consecutive individual patients were recruited at their hospital appointment...
October 24, 2016: BMJ Open
https://www.readbyqxmd.com/read/27783239/risk-scores-as-useful-predictors-of-perioperative-complications-in-patients-with-rectal-cancer-who-received-radical-surgery
#10
Hiroshi Miyakita, Sotaro Sadahiro, Gota Saito, Kazutake Okada, Akira Tanaka, Toshiyuki Suzuki
BACKGROUND: Rectal cancer is associated with a higher rate of surgical complications. The ability to predict the risk of complications before treatment would facilitate the design of personalized treatment strategies optimally suited for each patient. METHODS: We retrospectively studied 260 patients with rectal cancer who underwent radical surgery to examine the relations between complications and 5 types of risk scores. RESULTS: Complications developed in 56 patients (21...
October 25, 2016: International Journal of Clinical Oncology
https://www.readbyqxmd.com/read/27753246/prospective-randomized-controlled-study-on-the-validity-and-safety-of-an-absorbable-adhesion-barrier-interceed%C3%A2-made-of-oxidized-regenerated-cellulose-for-laparoscopic-colorectal-surgery
#11
Masanori Naito, Naoto Ogura, Takahiro Yamanashi, Takeo Sato, Takatoshi Nakamura, Hirohisa Miura, Atsuko Tsutsui, Yasutoshi Sakamoto, Rieko Tanaka, Yuji Kumagai, Masahiko Watanabe
INTRODUCTION: Clinical use of an adhesion barrier made of oxidized, regenerated cellulose, Interceed®, has been reported in the field of obstetrics and gynecology to help prevent adhesions between the peritoneum and the bowel in various types of operations. In gastrointestinal surgery, sodium hyaluronate/carboxymethylcellulose has been reported as an absorbable membrane to reduce postoperative adhesions. The present study was a prospective randomized controlled study to investigate the safety and usefulness of Interceed in laparoscopic colorectal surgery...
October 18, 2016: Asian Journal of Endoscopic Surgery
https://www.readbyqxmd.com/read/27749477/outcomes-in-colorectal-surgeon-driven-management-of-obstructing-colorectal-cancers
#12
Shunji Morita, Kimimasa Ikeda, Takamichi Komori, Tsukasa Tanida, Hisanori Hatano, Yoshito Tomimaru, Hiroshi Imamura, Keizo Dono
BACKGROUND: Emergency surgery for obstructing colorectal cancer is associated with high mortality and morbidity rates. OBJECTIVE: The purpose of this study was to assess outcomes of emergency surgery for obstructing colorectal cancer in a single hospital, where care was primarily provided by colorectal surgeons. DESIGN: This was a retrospective cohort study. SETTINGS: The study was conducted at the Toyonaka Municipal Hospital...
November 2016: Diseases of the Colon and Rectum
https://www.readbyqxmd.com/read/27742029/should-patients-with-obstructing-colorectal-cancer-have-proximal-diversion
#13
Chaya Shwaartz, Adam C Fields, Jake G Prigoff, Jeffrey J Aalberg, Celia M Divino
BACKGROUND: Up to 20% of patients with colorectal cancer present with obstruction. The goal of this study was to compare the short-term outcomes of patients with obstructing colon cancer who underwent resection and primary anastomosis with or without proximal diversion. METHODS: The American College of Surgeons' National Surgical Quality Improvement Program Procedure Targeted Colectomy databases from 2012 to 2014 were reviewed. Patients undergoing colorectal resection with or without diverting ostomy for obstructing colorectal cancer were analyzed...
September 2, 2016: American Journal of Surgery
https://www.readbyqxmd.com/read/27725925/examination-of-physicians-perception-of-the-indications-of-colorectal-stents-in-the-management-of-malignant-large-bowel-obstruction-a-provincial-survey
#14
Jean-Frédéric LeBlanc, Myriam Martel, Alan N Barkun
Introduction. Data are conflicting when assessing indications for colorectal self-expandable metallic stents (SEMS) in managing acute malignant large bowel obstruction (MLO). In November 2014, European and American Societies published guidelines to aid in understanding which patients might benefit from colorectal stenting. Yet, there remain marked disparities in clinical practice. Methods. A web-based survey was sent to Gastroenterologists and Surgical Specialists across Quebec to assess physicians' knowledge and adherence to the indications for colonic SEMS placement in the management of MLO using eight clinical scenarios...
2016: Canadian Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/27695974/gastrointestinal-tract-anastomoses-with-the-biofragmentable-anastomosis-ring-is-it-still-a-valid-technique-for-bowel-anastomosis-analysis-of-203-cases-and-review-of-the-literature
#15
Adam Bobkiewicz, Adam Studniarek, Lukasz Krokowicz, Krzysztof Szmyt, Maciej Borejsza-Wysocki, Jacek Szmeja, Ryszard Marciniak, Michal Drews, Tomasz Banasiewicz
PURPOSE: Biofragmentable anastomosis ring (BAR) is an alternative to manual and stapled anastomoses performed within the upper and lower gastrointestinal (GI) tract. The aim of this study was to evaluate the effectiveness of BAR utility for bowel anastomoses based on our own material. METHODS: A retrospective analysis was performed to a total of 203 patients who underwent bowel surgery with the use of BAR anastomosis within upper and lower gastrointestinal tract between 2004 and 2014...
September 30, 2016: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/27689329/age-and-cellular-context-influence-rectal-prolapse-formation-in-mice-with-caecal-wall-colorectal-cancer-xenografts
#16
Joke Tommelein, Félix Gremonprez, Laurine Verset, Elly De Vlieghere, Glenn Wagemans, Christian Gespach, Tom Boterberg, Pieter Demetter, Wim Ceelen, Marc Bracke, Olivier De Wever
In patients with rectal prolapse is the prevalence of colorectal cancer increased, suggesting that a colorectal tumor may induce rectal prolapse. Establishment of tumor xenografts in immunodeficient mice after orthotopic inoculations of human colorectal cancer cells into the caecal wall is a widely used approach for the study of human colorectal cancer progression and preclinical evaluation of therapeutics. Remarkably, 70% of young mice carrying a COLO320DM caecal tumor showed symptoms of intussusception of the large bowel associated with intestinal lumen obstruction and rectal prolapse...
September 28, 2016: Oncotarget
https://www.readbyqxmd.com/read/27687428/bilateral-tension-pneumothorax-during-colonoscopy-in-a-patient-with-chronic-obstructive-pulmonary-disease-a-case-report
#17
Wei-Cheng Tseng, Chun-Chang Yeh, Shu-Wen Jao, Zhi-Fu Wu, Shinn-Long Lin
Colonoscopy is widely performed for the diagnosis and treatment of various colonic disorders and the screening and surveillance of colorectal neoplasia. According to research evidence, up to one-third of patients had at least 1 minor and transient gastrointestinal symptom after colonoscopy. Although severe complications developed uncommonly, they are potentially serious and life threatening. Here, we present the case of a 95-year-old man with chronic obstructive pulmonary disease who developed bilateral tension pneumothorax during therapeutic colonoscopy for sigmoid volvulus...
November 2016: Journal of Clinical Anesthesia
https://www.readbyqxmd.com/read/27677113/synchronous-male-breast-and-colon-cancer-presenting-with-ileus-a-case-report
#18
Aziz Ari, Cihad Tatar, Kenan Buyukasik, Ozgur Segmen, Coskun Cakir, Soykan Arikan
INTRODUCTION: Cancer developing from more than one origin is called multiple primary cancer (MPC) and is a rare situation. In this article, we report a case presenting to the Emergency Clinic with symptoms of ileus who was diagnosed with synchronous colon and breast cancer. PRESENTATION OF CASE: A 57year old male patient presented to the Emergency Clinic with abdominal pain, vomiting, constipation and lack of flatulence. The patient was taken to the operating room for emergency surgery with the diagnosis of intestinal obstruction...
September 22, 2016: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/27672293/transanal-surgery-for-obstructed-defecation-syndrome-literature-review-and-a-single-center-experience
#19
REVIEW
Wei-Cheng Liu, Song-Lin Wan, S M Yaseen, Xiang-Hai Ren, Cui-Ping Tian, Zhao Ding, Ken-Yan Zheng, Yun-Hua Wu, Cong-Qing Jiang, Qun Qian
Obstructed defecation syndrome (ODS) is a functional disorder commonly encountered by colorectal surgeons and gastroenterologists, and greatly affects the quality of life of patients from both societal and psychological aspects. The underlying anatomical and pathophysiological changes of ODS are complex. However, intra-rectal intussusception and rectocele are frequently found in patients with ODS and both are thought to play an important role in the pathogenesis of ODS. With the development of evaluation methods in anorectal physiology laboratories and radiology studies, a great variety of new operative procedures, especially transanal procedures, have been invented to treat ODS...
September 21, 2016: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/27652303/three-cases-of-endoscopic-resection-for-synchronous-early-colon-cancers-after-self-expandable-metallic-stent-placement-for-obstructive-colon-cancer
#20
Rintaro Moroi, Katsuya Endo, Ryo Ichikawa, So Takahashi, Takeharu Shiroki, Hirohiko Shinkai, Fumitake Ishiyama, Shoichi Kayaba
The feasibility of endoscopic resection for synchronous early colon cancer after placement of self-expandable metallic stents (SEMS) for malignant colorectal obstruction is unknown. Herein we evaluated 3 cases of endoscopic resection for synchronous early colorectal cancers after SEMS placement. Patient 1 was an 82-year-old man with obstructive sigmoid colon cancer. We curatively treated the synchronous descending colon cancer with endoscopic submucosal dissection (ESD) and the rectal cancer with endoscopic mucosal resection (EMR) after SEMS placement...
September 2016: Endoscopy International Open
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