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Colon cancer obstruction

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https://www.readbyqxmd.com/read/28711762/olgilvie-s-syndrome-after-robotic-assisted-radical-hysterectomy-for-cervical-cancer
#1
Theofano Orfanelli, Stephanie Chung, Adrian Kohut, Darlene Gibbon, Aliza Leiser
The Acute Colonic Pseudo-Obstruction (ACPO), also known as Ogilvie's syndrome, is defined by a poor peristaltic activity of the colon that mimics mechanical obstruction in the absence of any mechanical occlusive gut lesion. This case report is the first to be published on ACPO following a robotic- assisted radical hysterectomy. Since robotic-assisted laparoscopic surgery has become the next major stage of advancement for a range of operations especially in gynecologic oncology surgery, this report emphasizes the importance of recognizing precipitating factors associated with this syndrome, including minimally invasive surgery...
July 12, 2017: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/28706919/microbiome-in-chronic-obstructive-pulmonary-disease
#2
REVIEW
Eduard Monsó
The introduction of culture-independent techniques for the microbiological analysis of respiratory samples has confirmed that the respiratory system hosts a large number of microorganisms, which include a wide range of bacteria. The regular exposure to tobacco smoke changes the microbiome in healthy smokers, first in the oropharynx, increasing the presence of a restricted number of genera which attain high relative abundance, a pattern that may be considered as dysbiosis. In chronic obstructive pulmonary disease (COPD), microbiome analyses of sputum samples have demonstrated an important decline in bacterial diversity, with a change to a restricted flora with an overrepresentation of the Proteobacteria phylum, which include most of the bacteria commonly considered as potentially pathogenic microorganisms, paralleled by a decline in the relative abundance of microorganisms part of the Firmicutes phylum...
June 2017: Annals of Translational Medicine
https://www.readbyqxmd.com/read/28652754/unusual-delayed-presentation-of-diaphragmatic-hernia-complicated-by-transverse-colon-and-total-small-bowel-obstruction-after-postoperative-chemotherapy-of-esophageal-cancer
#3
Yanlai Sun, Lei Yin, Hongfan Xue, Haipeng Wang, Zengjun Li, Jinming Yu
Diaphragmatic hernia (DH) is defined as the passage of abdominal contents into the chest cavity through a defect in the diaphragm. DH occurs after chest or abdominal surgery, and is very rare and sporadically reported in the literature. However, the complications are significant and put the patient at great risk. The aim of the present report was to describe a special case with postesophagectomy diaphragmatic hernia (PDH) because of its appearance during chemotherapy and confusion of the symptoms with the side effects of chemotherapy...
2017: Therapeutics and Clinical Risk Management
https://www.readbyqxmd.com/read/28651879/unexpected-diagnosis-of-colon-cancer-due-to-obstruction-of-the-large-intestine-by-impaction-of-the-shell-of-a-bivalve
#4
Ángel Pareja López, Jaime Jorge Cerrudo, María Amadora Alonso Fernández
No abstract text is available yet for this article.
June 23, 2017: Medicina Clínica
https://www.readbyqxmd.com/read/28643316/-endoscopic-metallic-stent-followed-by-elective-laparoscopic-surgery-for-malignant-colorectal-obstruction
#5
Qingping Lu, Qilong Lan, Long Chen, Dongbo Xu, Jun Li, Shuangmin Lin, Changrong Que, Jianxun Chen
OBJECTIVE: To investigate the feasibility of endoscopic metallic stent as a bridge to elective laparoscopic surgery in patients with malignant colorectal obstruction. METHODS: Clinical data of 63 patients with obstructive colorectal cancer who underwent endoscopic metallic stent insertion under radiologic monitoring at the Longyan First Hospital between June 2012 and August 2016 were analyzed retrospectively. After complete remission of the obstruction, all the patients received multi-disciplinary team (MDT) evaluation to make the further treatment strategy...
June 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/28621183/-colon-reconstruction-after-the-hartmann-procedure-laparoscopy-or-laparotomy
#6
Loránd Barabás, Ákos Szabó, Szilárd Szabó, Gábor Turcsányi, Csaba Sipos, Gábor István
The Hartmann procedure - primarily - was introduced for the treatment of cancerous diseases of sigmoid colon and rectum. In the last few years it was performed in cases with complicated inflammation of the left colon, colon cancers with bowel obstruction or perforation, or in the case of insufficiency of the anastomoses, or in urgent operations after traumatics bowel injuries, when making the anastomosis is at very high risk. Later on the restoration of the continuity of the GI tract can be done traditionally (by laparotomy) or laparoscopically...
June 2017: Magyar Sebészet
https://www.readbyqxmd.com/read/28616223/clinical-outcomes-of-self-expandable-metal-stent-sems-placement-as-palliative-treatment-for-malignant-colorectal-obstruction-a-single-center-study-from-japan
#7
Toshikatsu Nitta, Jun Kataoka, Masato Ohta, Kensuke Fujii, Tomo Tominaga, Yoshihiro Inoue, Hiroshi Kawasaki, Takashi Ishibashi
OBJECTIVES: We aimed to assess the efficacy of self-expanding metal stent (SEMS) implantation as palliative treatment for malignant colorectal obstruction. METHODS: We retrospectively reviewed the records of patients with malignant colorectal obstruction who underwent SEMS insertion as palliative treatment in our hospital between March 2013 and December 2016. We analyzed demographic, clinical, and operative characteristics. RESULTS: A total of 13 patients (8 males, 5 females; median age, 80...
July 2017: Annals of Medicine and Surgery
https://www.readbyqxmd.com/read/28614208/il-8-expression-in-granulocytic-epithelial-lesions-of-idiopathic-duct-centric-pancreatitis-type-2-autoimmune-pancreatitis
#8
Yuna Ku, Seung-Mo Hong, Kohei Fujikura, Sung Joo Kim, Masayuki Akita, Shiho Abe-Suzuki, Hideyuki Shiomi, Atsuhiro Masuda, Tomoo Itoh, Takeshi Azuma, Myung-Hwan Kim, Yoh Zen
Type 2 autoimmune pancreatitis (type 2 AIP) develops in isolation or sometimes in association with ulcerative colitis. Its diagnosis requires the histologic confirmation of granulocytic epithelial lesions (GELs) with no diagnostic biomarker currently available. This study aimed to elucidate the tissue expression of cytokines and their diagnostic value in this condition. In quantitative polymerase chain reaction for multiple cytokines using tissue-derived mRNA, the expression level of interleukin (IL)-8 was markedly higher in type 2 AIP than in type 1 AIP (P<0...
August 2017: American Journal of Surgical Pathology
https://www.readbyqxmd.com/read/28601656/prognostic-relevance-of-src-activation-in-stage-ii-iii-colon-cancer
#9
Julia Martinez Perez, Iker Lopez-Calderero, Carmen Saez, Marta Benavent, Maria L Limon, Reyes Gonzalez-Exposito, B Soldevilla, Maria C Riesco-Martinez, Javier Salamanca, Amancio Carnero, Rocio Garcia-Carbonero
Src belongs to a family of cytoplasmic tyrosine kinases that play a key role in tumor initiation and progression. Src activation has been associated with a more aggressive neoplastic phenotype and induces resistance to platinum agents in preclinical models. The aim of our study was to assess the prognostic and/or predictive value of Src activation in stage II-III colon cancer patients. pSrc expression was assessed in paraffin-embedded tumor samples by immunohistochemistry (phospho Y418, ab4816, Abcam). Cases were classified by staining intensity in four categories: no staining (0), weak (1+), moderate (2+) and intense (3+) staining...
June 7, 2017: Human Pathology
https://www.readbyqxmd.com/read/28591040/an-uncommon-cause-of-gastric-outlet-obstruction-a-case-report
#10
Manjusha Bandireddy, Noemi Baffy
RATIONALE: Metastatic involvement of the gastrointestinal tract is an uncommon scenario encountered in the clinical practice. Our case represents a gastric outlet obstruction (GOO) as a consequence of distant Transitional cell carcinoma (TCC) metastasis without any lymph node involvement in association with inflammatory stranding leading to extrinsic duodenal obstruction. PATIENT CONCERNS: We report an unusual case of a 73-year-old male presented with a five-week history of nausea, vomiting and abdominal pain due to the metastatic extension from TCC that had been considered in remission...
June 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28579348/ten-year-survival-after-endoscopic-stenting-as-a-bridge-to-surgery-in-obstructing-colon-cancer
#11
Bram Verstockt, Annelien Van Driessche, Marc De Man, Pieter van der Spek, Koen Hendrickx, Veerle Casneuf, Pieter Dobbels, Yves Van Molhem, Jo Vandervoort
BACKGROUND AND AIMS: Self-expandable metallic stents are increasingly used in the treatment of obstructing colorectal cancer (CRC). Although endoscopic colonic stenting is widely accepted in palliation, disagreement exists about its role in a curative setting. This study aims to describe long-term survival data in a large patient group, treated with colonic stenting as a bridge to surgery (BTS) for CRC. PATIENTS AND METHODS: This prospective study included 97 patients who presented in a Belgian hospital between 1998 and 2013 with an obstructing, though potentially curable, CRC...
June 1, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28575811/perforation-of-the-cecum-resulting-from-a-closed-loop-obstruction-in-a-patient-with-an-adenocarcinoma-of-the-sigmoid-colon-a-case-report
#12
Jefferson Sing Toledo, Marley Moreira Correia, Rafael Rodrigues Coutinho, Eduardo Fukamachi Kifer, Diego de Faria Magalhães Torres
INTRODUCTION: Bowel obstruction is one of the principal non-traumatic causes of general surgery emergencies, both in Brazil and worldwide. This condition can be classified according to the degree (complete or incomplete), clinical course (acute or chronic) or nature (mechanical, vascular or functional) of the obstruction. CASE REPORT: ESS, a 62-year old Brazilian woman from Rio de Janeiro, was admitted to the emergency department complaining of constipation of two weeks' duration...
2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28569279/safety-and-efficacy-of-self-expandable-metal-stents-for-obstructive-proximal-and-distal-large-bowel-cancer
#13
V Mitra, M Hu, D Majumdar, V Krishnan, B Chaudhury, J Hancock, D Dwarakanath
Self-expandable metal stents are often used to treat obstructive large bowel cancers. This study assessed the safety and efficacy of colonic stent insertion carried out in a district general hospital. Methods A retrospective review was carried out between 1 January 2007 and 28 February 2014 to identify patients who underwent stent insertion for malignant colorectal obstruction. Results Seventy-five patients (median age 75.2 years, 70.6% male) with primary colorectal cancer underwent stent insertion - 53 underwent semi-elective self-expanded metal stent insertion (for subacute bowel obstruction) and 22 had emergency stent inserted (for acute bowel obstruction)...
March 2017: Journal of the Royal College of Physicians of Edinburgh
https://www.readbyqxmd.com/read/28560018/internal-hernia-after-laparoscopic-right-hemicolectomy-report-of-a-case
#14
Hiroki Sugita, Takahiko Akiyama, Naoya Daitoku, Rumiko Tashima, Hiroshi Tanaka, Shinobu Honda, Tetsumasa Arita, Yasushi Yagi, Masahiko Hirota
Mesenteric defects are often not closed in laparoscopic colectomy. We herein report a case of an internal hernia projecting through a mesenteric defect following laparoscopy-assisted right hemicolectomy. A 74-year-old woman was hospitalized for the surgical treatment of double colon cancer. Preoperative colonoscopy demonstrated the presence of ascending colon and transverse colon cancers. A laparoscopic-assisted right hemicolectomy was performed. The mesenteric defect resulting from the colectomy was not closed...
May 2017: Journal of Surgical Case Reports
https://www.readbyqxmd.com/read/28537409/-ureterointestinal-anastomosis-in-urinary-diversion-current-opinion
#15
J Doležel
Uretero-intestinal anastomosis (UIA) is one of the most critical points for the occurrence of severe complications of intestinal urinary diversion. Perfection of the current techniques and development of new UIA methods are motivated by the effort to reduce both early and late post-surgical complications. The necessity of using antireflux UIA, especially with an orthotopic neobladder, is controversial: according to some authors, antireflux UIA of any type generally increases, in comparison with reflux UIA, the risk of obstruction that endangers renal function more than the urine reflux itself...
2017: Rozhledy V Chirurgii: Měsíčník Československé Chirurgické Společnosti
https://www.readbyqxmd.com/read/28516110/large-bowel-obstruction-following-endoscopic-spray-cryotherapy-for-palliation-of-rectal-cancer-bleeding
#16
Ravi Prakash, Digant Gupta, Pankaj Vashi
We report a unique case of a 79-year-old woman with metastatic rectal cancer who developed bowel obstruction following endoscopic cryotherapy with liquid nitrogen for palliation of bleeding in the rectum. She developed abdominal distention and pain following the procedure. Computed tomography of the abdomen revealed a paraumbilical hernia containing a segment of transverse colon resulting in partial bowel obstruction. It appears that the recurrent freeze-thaw cycles with poor decompression of the colon despite active venting suction during cryotherapy may have resulted in bowel distention and collapse, causing conformational changes resulting in partial bowel obstruction due to a paraumbilical hernia...
2017: ACG Case Reports Journal
https://www.readbyqxmd.com/read/28510798/total-laparoscopic-management-for-stage-iv-colorectal-cancer-requiring-multivisceral-resection
#17
Y Nancy You, Hironori Shiozaki, Jeffrey E Lee, Guillaume Passot, Claire Goumard, Masayuki Okuno, Thomas A Aloia, Cathy Eng, George Chang, Jean-Nicolas Vauthey, Claudius Conrad
BACKGROUND: Surgical resection of all sites of disease, in combination with effective systemic chemotherapy, offers the only potential chance for cure for patients with stage IV colorectal cancer (CRC). Coordinated multistage resection using a minimally invasive approach may provide optimal oncologic outcome while potentially offering the benefit of decreased morbidity. PATIENT: A 66-year-old women presented with transverse colon cancer and synchronous metastasis (CRLM) in segment IV involving the middle hepatic vein and main left portal pedicle, as well as the left adrenal gland...
May 16, 2017: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/28501245/emergency-presentations-of-colorectal-cancer
#18
REVIEW
Canaan Baer, Raman Menon, Sarah Bastawrous, Amir Bastawrous
Many colorectal carcinomas will present emergently with issues such as obstruction, perforation, and bleeding. Emergency surgery is associated with poor short- and long-term outcomes. For abnormality localizing to the colon proximal to the splenic flexure, surgical management with hemicolectomy is often a safe and appropriate approach. Obstructions are more common in the distal colon, however, where there is an evolving spectrum of surgical and nonsurgical options, most notably by the development of endoluminal stents...
June 2017: Surgical Clinics of North America
https://www.readbyqxmd.com/read/28490887/role-of-ct-scan-in-differentiating-the-type-of-colorectal-cancer
#19
Zhen-Hui Li, Ding-Yun You, De-Pei Gao, Guang-Jun Yang, Xing-Xiang Dong, Da-Fu Zhang, Ying-Ying Ding
OBJECTIVES: Most colorectal cancers are classical adenocarcinomas (AC), and less frequent subtypes include mucinous adenocarcinomas (MAC) and signet-ring cell carcinomas (SC). The purpose of this study was to evaluate the computed tomography (CT) findings that can help to differentiate MAC and SC from AC. METHODS: CT scans of 168 patients with pathologically proven MAC and 67 patients with pathologically proven SC were analyzed, and 220 patients with classical AC were also included as a control group...
2017: OncoTargets and Therapy
https://www.readbyqxmd.com/read/28488730/octreotide-associated-neutropenia
#20
Stacy S Tse, Troy Kish
Drug-induced neutropenia and agranulocytosis are rare adverse events but can be fatal. Neutropenia can be induced by a myriad of drugs from almost every pharmacologic class. Octreotide is a somatostatin analogue that has been used to treat variceal bleeding, acromegaly, and severe diarrhea associated with metastatic tumors, and to reduce symptoms in the setting of malignant bowel obstruction and pseudo-obstruction. The most common adverse effects associated with octreotide include pain at the injection site and gastrointestinal effects such as loose stools, cramping, and nausea; neutropenia is not currently listed as an adverse effect of the drug...
May 10, 2017: Pharmacotherapy
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