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Colon cancer obstruction

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https://www.readbyqxmd.com/read/29430222/long-term-colon-stent-patency-for-obstructing-colorectal-cancer-combined-with-bevacizumab
#1
Anouk E J Latenstein, Mathijs P Hendriks, Emo E van Halsema, Jeanin E van Hooft, Anne-Marie van Berkel
Self-expanding metal stents can be considered as initial treatment for malignant large bowel obstruction in the palliative setting. It is suggested that systemic anti-angiogenic therapy increases the risk of stent perforation. We report a 65-year-old woman with a metastatic, obstructing colon tumor who has been successfully treated with stent placement and chemoimmunotherapy consisting of capecitabine and bevacizumab for 8 years.
September 2017: Case Reports in Gastroenterology
https://www.readbyqxmd.com/read/29427286/first-experience-of-inserting-a-metallic-mesh-stent-uventa-stent-in-malignant-ureteral-obstruction-in-iran
#2
Mohammad Ali Ghaed, Maziar Daniali, Mohammad Ebrahimian
Malignant ureteral obstruction is usually caused by an extrinsic compression including intra-abdominal cancers. One of the treatment modalities decompressing the obstruction is applying stent to open the ureter. Metallic Stent is an effective instrument which we used for the first time in Iran in our patient who had a metastatic colon cancerwith a single kidney and we used a Novel, Double-Layered, Coated, Self-expandable Metallic Mesh Stent (Uventa Stent) to keep the ureter open. After six months of follow up with ureteroscopy, there was no obstruction any more...
February 10, 2018: Urology Journal
https://www.readbyqxmd.com/read/29427046/hepatobiliary-phase-liver-mr-imaging-findings-after-oxaliplatin-based-chemotherapy-in-cancer-patients
#3
REVIEW
Emre Ünal, Ali Devrim Karaosmanoğlu, Mustafa Nasuh Ozmen, Deniz Akata, Musturay Karcaaltincaba
OBJECTIVE: To describe Gd-EOB-DTPA-enhanced liver MR imaging findings in colon and rectal cancer patients who received Oxaliplatin. CONCLUSION: Spectrum of hepatobiliary phase imaging findings include diffuse heterogeneous dysfunction, macronodular and micronodular FNH-like lesions, and coexistence of periportal increased liver function with FNH-like lesions. Differentiation of these benign lesions from metastasis is crucial to avoid biopsy in patients with colorectal cancers and may allow better understanding of sinusoidal obstruction syndrome pathophysiology and regenerative response of liver...
February 9, 2018: Abdominal Radiology
https://www.readbyqxmd.com/read/29402880/adenocarcinoma-in-a-blind-loop-of-the-ileum-53-years-after-an-ileotransversostomy-procedure
#4
Ryohei Takei, Ichiro Onishi, Ryosuke Zaimoku, Naoki Makita, Yasumichi Yagi, Masato Kayahara
BACKGROUND Primary small bowel cancer is a rare malignancy; the common histopathological types are carcinoid and adenocarcinoma. Inflammatory bowel diseases and familial adenomatous polyposis are known risk factors for small bowel cancer. Additionally, cases of surgery-induced small bowel adenocarcinoma are sometimes reported after ileostomy. CASE REPORT A 84-year-old woman, who had undergone ileotransversostomy for intestinal obstruction due to postoperative adhesion following appendectomy at the age of 31 years, was referred to our hospital for further examination after experiencing abdominal pain in the right lower quadrant for 2 weeks...
February 6, 2018: American Journal of Case Reports
https://www.readbyqxmd.com/read/29394837/-a-case-of-resection-of-obstructive-colon-cancer-associated-with-aspiration-pneumonia-under-combined-epidural-spinal-anesthesia
#5
Kazuki Hayashi, Kohei Murata, Atsushi Naito, Yoshinori Kagawa, Kenji Kawai, Ryota Mori, Yohei Nose, Yasuki Akiyama, Takuya Sakamoto, Kohei Murakami, Tohru Masuzawa, Yoshiteru Katsura, Yoshiaki Ohmura, Atsushi Takeno, Yutaka Takeda
An 89-year-old woman was admitted to our hospital with vomiting, abdominal distension, and anorexia.A CT scan revealed an enhanced thickening lesion on the wall of the ascending colon, and intestinal expansion from the small intestine to the caecum.On colon fibroscopy, a round tumor was observed adjacent to the oral side of the hepatic flexure even though the end of the microscope could not progress toward the deeper regions.As the obstructive colon cancer was complicated by the presence of aspiration pneumonia, surgery could not be performed under general anesthesia...
November 2017: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/29394829/-sixteen-cases-of-colon-stenting-as-a-bridge-to-surgery-bts-for-obstructive-colorectal-cancer
#6
Ryo Otsuka, Shuji Saito, Ryouichi Hirayama, Yasuaki Miura, Kazunori Sasaki, Ayako Miyajima, Nobutsuna Kuwamoto, Ryoko Kataoka, Yukito Shindo, Rikiya Fujita
INTRODUCTION: Colonic stent insertion is widely used as a bridge to surgery(BTS)for obstructive colorectal cancer. Stenting can shorten hospitalization and decrease complication and colostomy rates in comparison with emergency surgery. We investigated patients who underwent colonic stent insertion for BTS in our hospital. PATIENTS: Sixteen patients(8 men, 8 women) with a colorectal obstruction score of 0 or 1 who underwent colonic stent insertion as a BTS between April 2015 and April 2017 period were investigated...
November 2017: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/29394819/-a-case-of-phrenic-nerve-paralysis-during-adjuvant-chemotherapy-for-rectal-cancer
#7
Nobushige Yabe, Eri Tamura, Keiichiro Kitahama, Hiroki Ozawa, Yuki Tajima, Takashi Takenoya, Ippei Oto, Takahisa Yoshikawa, Kenji Kojima, Shinji Murai, Hirotoshi Hasegawa, Yuko Kitagawa
A man aged 66 years presented with pneumaturia as a major complaint. Cancer of the sigmoid colon with infiltration to the urinary bladder was diagnosed and the patient underwent colectomy of the sigmoid colon and partial cystectomy of the bladder in May 2015. Histopathologic examinations revealed pT4b, Si(bladder), pN(-), cM0, fStage II . Because intestinal sub-obstruction and lymphatic invasion were present, CapeOX was administered as an adjunctive chemotherapy for the high-risk Stage II cancer. Because Grade 2 peripheral neuropathy appeared as a side effect, the dose was decreased to 80% from the 3 cycle...
November 2017: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/29394818/-a-case-of-synchronous-multiple-liver-metastases-from-ascending-colon-cancer-showing-pathological-complete-response-to-capeox-treatment
#8
Kaori Okugawa, Emiko Ioka, Tatsuki Ishikawa, Masakazu Takemoto, Masafumi Osaka, Yayoi Kadotani, Katsunori Nakano, Kiyokazu Akioka, Yoshio Osaka, Kuniyuki Tsuchiya
The patient was a 30-year-old man who underwent a medical examination for shortness of breath.An abdominal computed tomography(CT)scan revealed advanced ascending colon cancer with multiple metastases to the liver.We performed a laparoscopic right hemicolectomy first, due to the obstruction.Postoperatively, the patient received capecitabine plus oxaliplatin( CapeOX)chemotherapy.After 10 courses of CapeOX, the multiple liver metastases had reduced remarkably in size. Colectomy of the anastomosis and partial hepatectomy were then performed...
November 2017: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/29394803/-obstructive-colon-cancer-with-triple-vessel-coronary-artery-disease-a-case-report
#9
Koji Ueda, Seiichi Shinji, Yosuke Ishii, Hiroshi Yamawaki, Takeshi Yamada, Michihiro Koizumi, Yasuyuki Yokoyama, Masahiro Hotta, Goro Takahashi, Takuma Iwai, Kohki Takeda, Keisuke Hara, Keiichirou Oota, Takashi Nitta, Eiji Uchida
The patient was a 70-year-old woman who was diagnosed with obstructive transverse colon cancer suspected of invading the abdominal wall by abdominal CT imaging. Since the preoperative electrocardiogram showed an ischemic change, echocardiography and coronary angiography were performed. We diagnosed chronic heart failure and angina pectoris because echocardiography showed low cardiac function(left ventricular ejection fraction; LVEF 37%)and coronary angiography indicated triple-vessel disease. We firstly performed coronary artery bypass graft surgery following self-expanding metallic stent placement as a bridge to surgery(BTS), because we judged this patient as a perioperative high-risk case...
November 2017: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/29394751/-a-case-of-curatively-resected-ascending-colon-cancer-with-ovarian-metastasis-and-peritoneal-dissemination-after-chemotherapy
#10
Yasushi Mochizuki, Hideaki Karasawa, Hideki Shimodaira, Shinobu Ohnuma, Kazuhiro Watanabe, Shimpei Maeda, Munenori Nagao, Takeshi Aoki, Katsuyoshi Kudo, Naoki Tanaka, Hiroaki Musha, Fuyuhiko Motoi, Takashi Kamei, Takeshi Naitoh, Michiaki Unno
A52 -year-old woman was diagnosed with ascending colon cancer with ovarian metastasis and peritoneal dissemination. Since the patient did not have symptoms with intestinal obstruction, mFOLFOX6 plus bevacizumab(Bmab)was performed for 12 cycles. After chemotherapy, the tumors of ascending colon and ovary were significantly shrunken and novel distant metastasis was not observed by CT scans. Therefore, the tumors were considered to be resectable and curative resection was performed. In the surgical findings, the peritoneal disseminations were localized, and right colectomy, bilateral oophorectomy and extirpation of the peritoneal disseminations were performed...
November 2017: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/29394717/-experiences-of-colonic-stents-in-patients-with-colonic-stenosis-due-to-peritoneal-dissemination-of-gastric-cancer
#11
Ryohei Kawabata, Masato Yoshikawa, Chizu Kameda, Akihiro Takata, Akinobu Yasuyama, Tae Matsumura, Chikato Koga, Masahiro Murakami, Masaki Hirota, Shingo Noura, Junzo Shimizu, Junichi Hasegawa
Stoma is a treatment option often adopted for large bowel obstruction accompanying peritoneal dissemination of gastric cancer, but the invasiveness of this intervention can be an issue for patients with limited prognosis and reduced quality of life. In our hospital, colonic stenting for bowel obstruction due to peritoneal dissemination from gastric cancer was performed for 7 consecutive patients. Oral ingestion became possible in 5 cases, and colonic stent was considered a useful treatment choice for appropriate cases...
November 2017: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/29394701/-experience-of-ramucirumab-plus-folfiri-as-second-line-treatment-for-metastatic-colorectal-cancer-in-our-hospital
#12
Shigeta Hagino, Takashi Miyata, Koya Sakamoto
We experienced 2 cases in which ramucirumab plus FOLFIRI as second-line treatment was beneficial. Case 1 was a 67-yearold man, underwent panitumumab plus mFOLFOX6 as first-line treatment for unresectable rectal cancer with ureteral invasion and multiple liver metastases, but the disease became worse at 9.3 months. We changed to ramucirumab plus FOLFIRI as second-line treatment. After 2 courses, a grade 3 febrile neutropenia was observed, but treatment was beneficial and continued administration for 9 months or more...
November 2017: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/29394661/-two-cases-of-single-incision-laparoscopic-ileocecal-resection-for-patients-over-90-with-colon-cancer
#13
Tsuyoshi Takagi, Hiroki Kobayashi, Shouji Hirajima, Kanehisa Fukumoto
Single-incision laparoscopic surgery(SILS)is superior to multiport laparoscopic surgery in terms ofcosmetics, but in other terms it is still disputable and needs further investigation. The treatment of SILS for colon cancer has increased, however, the feasibility of single-incision laparoscopic colectomy(SILC)for patients over 90 with colon cancer has not been well examined. We report 2 cases ofsingle -incision laparoscopic ileocecal resection without complications. Case 1: A 104-year-old woman who had been diagnosed with pStage III a obstructive ascending colon cancer...
November 2017: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/29394655/-a-difficult-case-of-invagination-of-the-protruding-colon-cancer
#14
Shinichi Yoshioka, Yoshio Oka, Kaoru Okada, Shigeyuki Ueshima, Naozumi Higaki, Hirohito Hayashida, Riichiro Nezu
A 88-year-old female suffered of ileus due to advanced transverse colon cancer. Pneumonia was observed and nutrient condition was bad. Operation was found to be difficult because of the bad condition with complication on this present time. Self-expandable metallic stent(SEMS)was inserted to extend obstruction. But SEMS dropped out next day and SEMS, thicker than previous one, was reinserted. Main tumor was huge protruding tumor and the reason of ileus was invagination of the cancer. The fixation of SEMS was not so good, but the generalcondition was improved while a week after reinsertion of SEMS...
November 2017: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/29394646/-two-cases-of-non-occlusive-mesenteric-ischemia-that-developed-after-chemotherapy
#15
Takahiro Wada, Kenji Katsumata, Hiroshi Kuwahara, Takaaki Matsudo, Yusuke Murakoshi, Masatoshi Shigoka, Masanobu Enomoto, Tetsuo Ishizaki, Kazuhiko Kasuya, Akihiko Tsuchida
Non-occlusive mesenteric ischemia(NOMI)causes intestinal necrosis due to irreversible ischemia of the intestinal tract despite the absence of organic obstruction in the mesenteric blood vessels. The disease has extremely poor prognosis. We encountered 2 cases of NOMI hypothesized to have developed after chemotherapy; thus, we report these cases considering the available literature. Case 1: A7 9-year-old man. The patient complained of abdominal pain during the first week after introducing docetaxel for local recurrence of prostate cancer...
November 2017: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/29394642/-a-case-of-advanced-sigmoid-colon-cancer-successfully-resected-via-laparoscopic-surgery-after-preoperative-chemotherapy
#16
Ryoji Nonaka, Kei Adachi, Jeong-Ho Moon, Yujiro Fujie, Kazuhiko Hashimoto, Shoichiro Fujita, Tadashi Ohnishi
We report a case of advanced sigmoid colon cancer resected via laparoscopic surgery after preoperative chemotherapy. A- 55-year-old man visited our hospital with diarrhea. CTrevealed a giant tumor in the sigmoid colon, and surrounding lymph node enlargement was also noted. The tumor appeared to be locally advanced; thus, preoperative chemotherapy was started. Due to the possibility of obstruction, we constructed an ileostomy laparoscopically. The tumor was found to be RAS wild, and 4 courses of mFOLFOX6 plus panitumumab were given...
November 2017: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/29394595/-two-cases-of-colon-cancer-with-severe-liver-dysfunction-due-to-multiple-liver-metastases-effectively-treated-with-hepatic-arterial-infusion-chemotherapy-plus-cetuximabfollowed-by-systemic-chemotherapy
#17
Fukuichiro Orita, Toshiaki Ishikawa, Megumi Sasaki, Tomiyuki Miura, Michiyo Tokura, Marie Hanaoka, Shinichi Yamauchi, Akifumi Kikuchi, Megumi Ishiguro, Masamichi Yasuno, Hiroyuki Uetake
Case 1: An 80-year-old man was diagnosed with cecal cancer plus multiple liver metastases and peritoneal disseminations. He underwent surgical resection of the primary tumor to prevent bowel obstruction. Initially, hepatic arterial infusion(HAI) plus cetuximab(Cmab)was administered to reduce the size of the metastatic tumors and prevent liver failure. A partial response(PR)was observed in the liver metastases after 12 courses of treatment and S-1 plus oxaliplatin(SOX)plus bevacizumab was started. Case 2: A 44-year-old man was diagnosed with sigmoid colon cancer with multiple liver, lung and bone metastases, and with obstructive jaundice and cholangitis due to severe liver hilum lymph node metastases...
November 2017: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/29394593/-findings-from-total-colonoscopy-in-obstructive-colorectal-cancer-patients-who-underwent-stent-placement-as-a-bridge-to-surgery-bts
#18
Hirotoshi Maruo, Hajime Tsuyuki, Tadahiro Kojima, Ryohei Koreyasu, Koichi Nakamura, Yukihiro Higashi, Tsuyoshi Shoji, Masanori Yamazaki, Raisuke Nishiyama, Tatsuhiro Ito, Kota Koike, Takashi Ikeda, Yasuhiro Takayanagi, Hiroyuki Kubota
We clinically investigated 34 patients with obstructive colorectal cancer who underwent placement of a colonic stent as a bridge to surgery(BTS), focusing on endoscopic findings after stent placement.Twenty -nine patients(85.3%)underwent colonoscopy after stent placement, and the entire large intestine could be observed in 28(96.6%).Coexisting lesions were observed in 22(78.6%)of these 28 patients.The lesions comprised adenomatous polyps in 17 patients(60.7%), synchronous colon cancers in 5 patients(17.9%), and obstructive colitis in 3 patients(10...
November 2017: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/29394590/-results-of-preoperative-colon-stent-placement-for-obstructive-colorectal-cancer
#19
Hajime Tsuyuki, Hirotoshi Maruo, Tadahiro Kojima, Ryohei Koreyasu, Koichi Nakamura, Yukihiro Higashi, Tsuyoshi Shoji, Masanori Yamazaki, Raisuke Nishiyama, Tatsuhiro Ito, Kota Koike, Takashi Ikeda, Yasuhiro Takayanagi, Hiroyuki Kubota
We examined short-term outcomes in 34 patients who had stenting as a bridge to surgery(BTS)for obstructive colorectal cancer during the 5-year period between April 2012 and March 2017.T he patients were 22 men and 12 women with a mean age of 72.6 years. Stenting and decompression were successful in all patients, and the mean time to oral intake after stenting was 2.5 days.No serious complications related to stenting occurred.Elective surgery could be performed in all patients after stenting.The mean number of days to surgery was 24...
November 2017: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/29394554/-laparoscopic-surgery-for-an-intussusception-caused-by-rectosigmoid-colon-cancer-after-pre-operative-reduction-by-transanal-insertion-of-a-circular-sizer-a-case-report
#20
Toshifumi Watanabe, Shiro Terai, Yusuke Haba, Katsuhisa Hirano, Yuki Yamasaki, Tomoya Tsukada, Masaki Takeshita, Koshi Matsui, Koji Amaya, Masahide Kaji, Kiichi Maeda, Koichi Shimizu
An octogenarian man complaining of bloody stool was referred to our hospital. A digital examination, abdominal enhanced CT and endoscopy led to a diagnosis of intussusception due to rectosigmoid colon cancer, but he was not suffering from bowel obstruction. An elective laparoscopic Hartmann's operation was performed after reduction by transanal insertion of a circular sizer. It may be difficult to reduce an intussusception induced by rectal cancer. We report this case with a review of the relevant literature...
November 2017: Gan to Kagaku Ryoho. Cancer & Chemotherapy
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