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https://www.readbyqxmd.com/read/27926617/robotic-approaches-for-the-rehabilitation-of-upper-limb-recovery-after-stroke-a-systematic-review-and-meta-analysis
#1
Chao Zhang, Cecilia W P Li-Tsang, Ricky K C Au
This systematic review with a meta-analysis of studies was carried out to evaluate the effectiveness of robotic training (RT) and conventional training (CT) in improving the motor recovery of paretic upper limbs in stroke patients. Numerous electronic databases were searched from January 2000 to May 2016. Finally, 13 randomized-controlled trials fulfilled the inclusion criteria and were included in the three meta-analyses. The first meta-analysis carried out for those studies using RT for stroke patients indicated a significant improvement in the RT groups...
December 6, 2016: International Journal of Rehabilitation Research. Revue Internationale de Recherches de Réadaptation
https://www.readbyqxmd.com/read/27925843/incidence-of-herpes-zoster-and-post-herpetic-neuralgia-in-italy-results-from-a-three-years-population-based-study
#2
Cristiano Alicino, Cecilia Trucchi, Chiara Paganino, Ilaria Barberis, Sara Boccalini, Domenico Martinelli, Barbara Pellizzari, Angela Bechini, Andrea Orsi, Paolo Bonanni, Rosa Prato, Stefania Iannazzo, Giancarlo Icardi
Herpes Zoster (HZ) and its main complication, post-herpetic neuralgia (PHN), represent important public health issues because of their relevant burden among older adults. However, data on the epidemiology of HZ and PHN in Italy are very limited. A population-based study was performed by seeking for cases of HZ and PHN, occurred in the period 2013-2015, in the clinical charts of 56 General Practitioners working in four Italian Regions (Liguria, Puglia, Toscana and Veneto). The main objective of the study was to estimate the incidence of HZ and the proportion of PHN (at 1 and 3 months from the onset of HZ; PHN1 and PHN3) among people aged ≥ 50 years...
December 7, 2016: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/27925224/fluorescent-protein-photoprotein-fusions-and-their-applications-in-calcium-imaging
#3
Adil Bakayan, Beatriz Domingo, Cecilia F Vaquero, Nadine Peyriéras, Juan Llopis
Calcium-activated photoproteins, such as aequorin, have been used as luminescent Ca(2+) indicators since 1967. After the cloning of aequorin in 1985, microinjection was substituted by its heterologous expression, which opened the way for a widespread use. Molecular fusion of GFP to aequorin recapitulated the nonradiative energy transfer process that occurs in the jellyfish Aequorea victoria, from which these two proteins were obtained, resulting in an increase of light emission and a shift to longer wavelength...
December 7, 2016: Photochemistry and Photobiology
https://www.readbyqxmd.com/read/27925078/factors-associated-with-the-occurrence-of-adverse-events-in-critical-elderly-patients
#4
Maria Cecilia Toffoletto, Ricardo Luis Barbosa, Rafaela Andolhe, Elaine Machado de Oliveira, Adriana Janzantte Ducci, Katia Grillo Padilha
Objective: to identify the factors associated with the occurrence of adverse events in critical elderly patients admitted to intensive care unit according to demographic and clinical characteristics. Method: a retrospective cohort study was conducted in nine units of a teaching hospital. Data were collected from medical records and from monitoring of nursing shift change. We used the t-test/Mann-Whitney, chi-square and logistic regression to test associations. Significance level of 5% was used...
November 2016: Revista Brasileira de Enfermagem
https://www.readbyqxmd.com/read/27925069/helminth-parasites-of-galictis-cuja-carnivora-mustelidae-from-localities-in-the-atlantic-forest-of-brazil
#5
Pilar Corrêa, Cecília Bueno, Fabiano Matos Vieira, Luís Cláudio Muniz-Pereira
The current study aimed to investigate the helminth parasites of a population of Galictis cuja (Carnivora, Mustelidae) that occur in Atlantic Forest in the Southeastern region of Brazil. We necropsied 18 specimens of G. cuja, collected between January 2009 and May 2014, ran over victims on BR-040 highway, between the municipalities of Duque de Caxias, state of Rio de Janeiro and Juiz de Fora, state of Minas Gerais, localities inserted in Atlantic rainforest Biome. A total of six species of helminths were identified: Dioctophyme renale, Molineus elegans, Physaloptera sp...
December 1, 2016: Revista Brasileira de Parasitologia Veterinária, Brazilian Journal of Veterinary Parasitology
https://www.readbyqxmd.com/read/27925063/negative-serosurvey-of-toxoplasma-gondii-antibodies-in-golden-headed-lion-tamarin-leontopithecus-chrysomelas-from-niter%C3%A3-i-rj-brazil
#6
Camila Vieira Molina, Felipe da Silva Krawczak, Marina Galvão Bueno, Herbert Sousa Soares, Solange Maria Genari, Alcides Pissinatti, Maria Cecília Martins Kierulff, Tiago Ferreira da Silva, Danilo Gomes de Freitas, Larissa Cristinne Caneli, José Luiz Catão-Dias
New World Nonhuman Primates are highly susceptible to clinical toxoplasmosis. Serum samples from 126 recently captured Leontopithecus chrysomelas, from an exotic and invasive population, were tested for Toxoplasma gondii antibodies by the modified agglutination test (MAT, cut-off 1:25); all were seronegative. The MAT is highly specific and is not species-specific. This is the first report of T. gondii survey in this tamarin in the wild. This result is consistent with prior reports that showed the high susceptibility of the species to infection by T...
December 1, 2016: Revista Brasileira de Parasitologia Veterinária, Brazilian Journal of Veterinary Parasitology
https://www.readbyqxmd.com/read/27925023/physical-activity-in-pregnancy-and-adverse-birth-outcomes
#7
Adriana Sousa Rêgo, Maria Teresa Seabra Soares de Britto E Alves, Rosângela Fernandes Lucena Batista, Cecília Claúdia Costa Ribeiro, Heloísa Bettiol, Viviane Cunha Cardoso, Marco Antonio Barbieri, Flávia Helen Furtado Loureiro, Antonio Augusto Moura da Silva
This study focused on the association between physical activity in the second trimester of pregnancy and adverse perinatal outcomes: low birth weight (LBW), preterm birth (PTB), and intrauterine growth restriction (IUGR). The study used a sample from the BRISA cohort, São Luís, Maranhão State, Brazil, which included women with singleton pregnancy, gestational age from 22 to 25 weeks confirmed by obstetric ultrasound performed at < 20 weeks, and re-interviewed in the first 24 hours postpartum (n = 1,380)...
December 1, 2016: Cadernos de Saúde Pública
https://www.readbyqxmd.com/read/27924684/fifteen-years-of-epidemiologic-virologic-and-syndromic-influenza-surveillance-a-focus-on-type-b-virus-and-the-effects-of-vaccine-mismatch-in-liguria-region-italy
#8
Cecilia Trucchi, Cristiano Alicino, Andrea Orsi, Chiara Paganino C, Ilaria Barberis, Federico Grammatico, Paola Canepa, Emanuela Rappazzo, Bianca Bruzzone, Laura Sticchi, Filippo Ansaldi
In order to estimate the burden of influenza and to describe the genetic evolutionary pattern and antigenic variability of type B viral strains, data deriving from three surveillance systems active in Liguria region, Northern Italy, were described. Since the re-emergence of the Victoria lineage in 2001, the clinical-epidemiological and syndromic surveillances demonstrated the heavy burden of influenza like illness (ILI) syndrome. Focusing on type B influenza virus, it predominated or played a relevant epidemic role in the 50% of the evaluated influenza seasons...
December 7, 2016: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/27924629/gas6-as-a-putative-noninvasive-biomarker-of-hepatic-fibrosis
#9
Mattia Bellan, Gabriele Pogliani, Cecilia Marconi, Rosalba Minisini, Lisa Franzosi, Federica Alciato, Andrea Magri, Gian Carlo Avanzi, Mario Pirisi, Pier Paolo Sainaghi
AIM: To evaluate serum growth arrest-specific gene 6 (Gas6) concentration as a biomarker of liver fibrosis progression. MATERIALS & METHODS: One hundred and thirteen consecutive patients affected by chronic liver disease underwent transient elastography, Gas6 measurement and, if clinically indicated, liver biopsy. RESULTS: Gas6 concentration was directly correlated to liver stiffness (r = 0.67; p < 0.0001) and was significantly higher in patients with advanced fibrosis (Ishak 4-5; p < 0...
December 7, 2016: Biomarkers in Medicine
https://www.readbyqxmd.com/read/27923992/sinorhizobium-meliloti-ybey-is-an-endoribonuclease-with-unprecedented-catalytic-features-acting-as-silencing-enzyme-in-riboregulation
#10
Margarida Saramago, Alexandra Peregrina, Marta Robledo, Rute G Matos, Rolf Hilker, Javier Serrania, Anke Becker, Cecilia M Arraiano, José I Jiménez-Zurdo
Structural and biochemical features suggest that the almost ubiquitous bacterial YbeY protein may serve catalytic and/or Hfq-like protective functions central to small RNA (sRNA)-mediated regulation and RNA metabolism. We have biochemically and genetically characterized the YbeY ortholog of the legume symbiont Sinorhizobium meliloti (SmYbeY). Co-immunoprecipitation (CoIP) with a FLAG-tagged SmYbeY yielded a poor enrichment in RNA species, compared to Hfq CoIP-RNA uncovered previously by a similar experimental setup...
December 6, 2016: Nucleic Acids Research
https://www.readbyqxmd.com/read/27923403/determinants-for-patient-satisfaction-regarding-aesthetic-outcome-and-skin-sensitivity-after-breast-conserving-surgery
#11
Cecilia Dahlbäck, Jonas Manjer, Martin Rehn, Anita Ringberg
BACKGROUND: With the development of new surgical techniques in breast cancer, such as oncoplastic breast surgery, increased knowledge of risk factors for poor satisfaction with conventional breast-conserving surgery (BCS) is needed in order to determine which patients to offer these techniques to. The aim of this study was to investigate patient satisfaction regarding aesthetic result and skin sensitivity in relation to patient, tumour, and treatment factors, in a consecutive sample of patients undergoing conventional BCS...
December 7, 2016: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/27923181/combined-oral-contraceptive-use-is-associated-with-both-improvement-and-worsening-of-mood-in-the-different-phases-of-the-treatment-cycle-a-double-blind-placebo-controlled-randomized-trial
#12
Cecilia Lundin, Kristina Gemzell Danielsson, Marie Bixo, Lena Moby, Hanna Bengtsdotter, Izabella Jawad, Lena Marions, Jan Brynhildsen, Agota Malmborg, Ingela Lindh, Inger Sundström Poromaa
OBJECTIVE: Ever since the introduction of combined oral contraception (COC), one of the major reasons for discontinuing the pill use has been mood-related side effects. Moreover, women who discontinue the pill turn to less effective methods whereby the probability of an unintended conception increases. Approximately 4-10% of COC users complain of depressed mood, irritability or increased anxiety, but drug-related causality has been difficult to prove. Given the lack of randomized controlled trials in this area, we aimed to prospectively estimate the severity of adverse mood in COC users that would be as representative of general users as possible...
November 29, 2016: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/27920261/effects-of-repetitive-transcranial-magnetic-stimulation-combined-with-sensory-cueing-on-unilateral-neglect-in-subacute-patients-with-right-hemispheric-stroke-a-randomized-controlled-study
#13
Nicole Yh Yang, Kenneth Nk Fong, Cecilia Wp Li-Tsang, D Zhou
OBJECTIVE: To compare the effects of rTMS combined with sensory cueing, rTMS alone, and conventional rehabilitation on unilateral neglect, hemiplegic arm functions and performance of activities of daily living. DESIGN: A single-blinded randomized controlled trial. SETTING: A convalescent hospital. SUBJECTS: Sixty inpatients with left unilateral neglect after stroke. INTERVENTIONS: Patients were randomly assigned to three groups: rTMS combined with sensory cueing, rTMS, and conventional rehabilitation alone...
December 5, 2016: Clinical Rehabilitation
https://www.readbyqxmd.com/read/27920120/effects-of-an-intervention-s%C3%A3-kl%C3%A3-k-on-prescription-of-potentially-inappropriate-medication-in-elderly-patients
#14
Cecilia Lenander, Åsa Bondesson, Nina Viberg, Ulf Jakobsson, Anders Beckman, Patrik Midlöv
BACKGROUND: Polypharmacy is known to increase the risk for drug-related problems, and some drugs, potentially inappropriate medications (PIMs), are especially troublesome. OBJECTIVE: To analyse the effects on prescription of PIMs of the SÄKLÄK project, an intervention model created to improve medication safety for elderly patients in primary care. METHOD: The SÄKLÄK project was a multiprofessional intervention in primary care consisting of self-assessment, peer review, feedback and written agreements for change...
December 5, 2016: Family Practice
https://www.readbyqxmd.com/read/27919697/apes-submentalise
#15
Cecilia Heyes
Making subtle and extensive use of eye-tracking technology, Krupenye and colleagues showed that, like human infants, great apes - chimpanzees, bonobos and orangutans - can accurately anticipate the goal-directed behaviour of an agent that holds a false belief. How do they do it, by mentalising or by submentalising?
December 2, 2016: Trends in Cognitive Sciences
https://www.readbyqxmd.com/read/27919438/does-an-increased-body-mass-index-affect-endometrial-gene-expression-patterns-in-infertile-patients-a%C3%A2-functional-genomics-analysis
#16
Ioanna A Comstock, Patricia Diaz-Gimeno, Sergio Cabanillas, Jose Bellver, Patricia Sebastian-Leon, Meera Shah, Amy Schutt, Cecilia T Valdes, Maria Ruiz-Alonso, Diana Valbuena, Carlos Simon, Ruth B Lathi
OBJECTIVE: To analyze the transcriptomic profile of endometrial gene alterations during the window of implantation in infertile obese patients. DESIGN: Multicenter, prospective, case-control study. SETTING: Three academic medical centers for reproductive medicine. PATIENT(S): Infertile patients, stratified into body mass index (BMI) categories according to the World Health Organization guidelines, were included in the study...
December 2, 2016: Fertility and Sterility
https://www.readbyqxmd.com/read/27919248/bone-mineral-density-in-patients-with-multiple-sclerosis-hereditary-ataxia-or-hereditary-spastic-paraplegia-after-at-least-10%C3%A2-years-of-disease-a-case-control-study
#17
Cecilia Smith Simonsen, Elisabeth Gulowsen Celius, Cathrine Brunborg, Chantal Tallaksen, Erik Fink Eriksen, Trygve Holmøy, Stine Marit Moen
BACKGROUND: Although disability is considered the main cause of low bone mineral density (BMD) in multiple sclerosis (MS), other factors related to the disease process or treatment could also be involved. The aim of this study was to assess whether patients with MS are more likely to develop low BMD (osteopenia or osteoporosis) than patients with the non-inflammatory neurological diseases Hereditary Spastic Paraplegia (HSP) and Hereditary Ataxia (HA). METHODS: We performed a case control study comparing BMD (spine, hip and total body) and biochemical measures of bone metabolism in 91 MS patients and 77 patients with HSP or HA, matched for age, gender and disability...
December 5, 2016: BMC Neurology
https://www.readbyqxmd.com/read/27918836/evolvix-best-names-for-semantic-reproducibility-across-code2brain-interfaces
#18
Laurence Loewe, Katherine S Scheuer, Seth A Keel, Vaibhav Vyas, Ben Liblit, Bret Hanlon, Michael C Ferris, John Yin, Inês Dutra, Anthony Pietsch, Christine G Javid, Cecilia L Moog, Jocelyn Meyer, Jerdon Dresel, Brian McLoone, Sonya Loberger, Arezoo Movaghar, Morgaine Gilchrist-Scott, Yazeed Sabri, Dave Sescleifer, Ivan Pereda-Zorrilla, Andrew Zietlow, Rodrigo Smith, Samantha Pietenpol, Jacob Goldfinger, Sarah L Atzen, Erika Freiberg, Noah P Waters, Claire Nusbaum, Erik Nolan, Alyssa Hotz, Richard M Kliman, Ayalew Mentewab, Nathan Fregien, Martha Loewe
Names in programming are vital for understanding the meaning of code and big data. We define code2brain (C2B) interfaces as maps in compilers and brains between meaning and naming syntax, which help to understand executable code. While working toward an Evolvix syntax for general-purpose programming that makes accurate modeling easy for biologists, we observed how names affect C2B quality. To protect learning and coding investments, C2B interfaces require long-term backward compatibility and semantic reproducibility (accurate reproduction of computational meaning from coder-brains to reader-brains by code alone)...
December 5, 2016: Annals of the New York Academy of Sciences
https://www.readbyqxmd.com/read/27918825/early-postnatal-hyperoxia-in-mice-leads-to-severe-persistent-vitreoretinopathy
#19
Paul G McMenamin, Rachel Kenny, Sjakon Tahija, Jeremiah Lim, Cecilia Naranjo Golborne, Xiangting Chen, Sheena Bouch, Foula Sozo, Bang Bui
Purpose: To describe a mouse model of hyperoxia-induced vitreoretinopathy that replicated some of the clinical and pathologic features encountered in infants with severe retinopathy of prematurity and congenital ocular conditions such as persistent hyperplastic primary vitreous. Methods: Experimental mice (C57BL/6J) were exposed to 65% oxygen between postnatal days (P)0 to P7 and studied at P10, P14, and 3, 5, 8, 20, and 40 weeks. Controls were exposed to normoxic conditions...
December 1, 2016: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/27918652/does-short-duration-heat-exposure-at-a-matched-cardiovascular-intensity-improve-intermittent-running-performance-in-a-cool-environment
#20
Calvin P Philp, Martin Buchheit, Cecilia M Kitic, Christopher T Minson, James W Fell
PURPOSE: To investigate whether a five-day cycling training block in the heat (35°C) in Australian rules footballers was superior to exercising at the same relative intensity in cool conditions (15°C) for improving intermittent running performance in a cool environment (<18°C). METHODS: Using a parallel-group design, 12 semi-professional football players performed five days of cycling exercise [70% heart rate reserve (HRR) for 45 min (5 x 50 min sessions in total)] in a hot (HEAT, 35±1°C, 56±9% RH) or cool environment (COOL, 15±3°C, 81±10% RH)...
December 5, 2016: International Journal of Sports Physiology and Performance
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