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Claire Gobron, Katayoun Vahedi, Eric Vicaut, Olivier Stucker, Elisabeth Laemmel, Nathalie Baudry, Marie Germaine Bousser, Hugues Chabriat
CADASIL (Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy) is caused by mutations in the Notch3 receptor expressed at the surface of vascular smooth muscle cells. The functional consequences of the disease at the peripheral microcirculation level are incompletely elucidated. In this study, we aimed to assess, in vivo, the endothelium-dependent and independent vasodilation of the skin microvasculature in CADASIL patients. Twenty-three affected subjects were compared with 23 gender and age-matched controls...
February 2007: Journal of Cerebral Blood Flow and Metabolism
N De Bellis
No abstract text is available yet for this article.
1969: L' Arcispedale S. Anna di Ferrara
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