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https://www.readbyqxmd.com/read/29749239/a-novel-fetal-sequence-patogenesis-resulting-in-oral-meningoencephalocele
#1
M Gabor, P Papcun, Jr M Krizko, Z Cierna, V Ferianec
OBJECTIVES: To analyze a rare triad of intracranial fetal pathologies and clinical study of the novel defined sequence pathogenesis based on prenatal and postmortem findings. METHODS: Complex multidisciplinary clinical analysis and review of up-to-date literature. RESULTS: In an 18-gestational-week fetus the screening ultrasound scan resembled the semilobar type of holoprosencephaly and oral tumor. After the indicated termination of pregnancy, the histopathology results confirmed another pathologies - oral meningoencephalocele, teratoma of the sellar area and large arachnoidal cyst of the anterior cerebral fossa...
2018: Bratislavské Lekárske Listy
https://www.readbyqxmd.com/read/29747250/-rare-primary-proximal-epithelioid-sarcoma-in-skull-base-clinical-analysis-of-four-cases
#2
Z J Duan, K Yao, Y M Qu, M Ren, Y L Zhang, X L Qi
Objective: To report the clinical and pathological features of primary proximal epithelioid sarcoma (PES) in skull base. Methods: The clinical and pathological features of four cases of PES in skull base from Sanbo Brain Institute of Capital Medical University and Kunming Sanbo Brain Institute were analysed retrospectively. Results: Three cases was female, and one male, the age ranged from 46 to 52 years.All cases occurred in skull base, and sellar region was the main site of involvement.Under the microscope, the tumor cells characterized by epithelioid cell changes, with or without rhabdoid tumor cells...
April 7, 2018: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
https://www.readbyqxmd.com/read/29743120/cavernous-sinus-involvement-in-human-papillomavirus-associated-oropharyngeal-squamous-cell-carcinoma-case-report-of-an-atypical-site-of-distant-metastasis
#3
David Forner, Derek Wilke, Matthew H Rigby, Sidney Croul, Anuradha Mishra, Emad Massoud, David B Clarke, Nathan Lamond
BACKGROUND: HPV-associated OSCC (HPV-OSCC) has been determined to be a distinct disease entity from non-HPV associated OSCC. Patients affected by HPV-OSCC generally have a more favourable prognosis, with improved rates of locoregional control and survival compared with their non-HPV counterparts. Despite this, HPV-OSCC has a similar rate of distant metastases. Interestingly, recent evidence has emerged that demonstrates more frequent atypical metastasis patterns when compared to non-HPV associated disease...
May 9, 2018: Journal of Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/29742711/pituitary-apoplexy-following-lumbar-fusion-surgery-in-prone-position-a-case-report
#4
Chunghee Joo, Geol Ha, Yeon Jang
RATIONALE: Pituitary apoplexy (PA) is a syndrome caused by acute hemorrhage or infarction of the pituitary gland, generally within a pituitary adenoma. PA following spinal surgery is a very rare complication and may be difficult to diagnose. However, early diagnosis of PA is essential for the timely treatment of pan-hypopituitarism and prevention of severe neurologic complications. PATIENT CONCERNS: A 73-year-old man had a posterior lumbar fusion surgery over a period of 8 hours on prone position...
May 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29730106/imaging-evaluation-of-the-location-and-fenestration-of-sellar-floor-during-endonasal-transsphenoidal-surgery-in-patients-with-pituitary-adenomas
#5
Shousen Wang, Yong Qin, Deyong Xiao, Zhifeng Wu, Liangfeng Wei
To evaluate the clinical value of three-dimensional (3D) CT reconstruction of the sphenoidal sinus separation in localizing sellar floor during endonasal transsphenoidal surgery, and determine the size and location of sellar floor fenestration. After exclusion,51 patients were eligible for study inclusion. A pre-operative CT scan of the paranasal sinus and CT scan and MRI of the pituitary gland were obtained. Sphenoidal sinus separation was reconstructed using Mimics 15.0 software and the quantity, shape, and orientation were observed and compared with intra-operative data, the purpose of which was to guide the localization of sellar floor...
May 3, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29721355/pituitary-fossa-chondrosarcoma-an-unusual-cause-of-a-sellar-suprasellar-mass-masquerading-as-pituitary-adenoma
#6
Gautam Dutta, Daljit Singh, Hukum Singh, Arvind Kumar Srivastava, Anita Jagetia, Deepashu Sachdeva
Background: Chondrosarcoma is a mesenchymal malignant tumor composed of tumor cells producing cartilage. It is more commonly found in older age group and usually affects the axial skeleton. Intracranial chondrosarcoma is extremely rare, and chondrosarcoma arising from the sellar region are even rarer with only a few cases described in the literature. We report a case of chondrosarcoma mimicking a sellar suprasellar mass with parasellar extension. Case Description: A 22-year old male presented with generalized intermittent headache along with diplopia and diminished visual acuity without any history of sexual dysfunction or galactorrhea...
2018: Surgical Neurology International
https://www.readbyqxmd.com/read/29675718/ultrasound-guided-brain-surgery-echographic-visibility-of-different-pathologies-and-surgical-applications-in-neurosurgical-routine
#7
Domenico Policicchio, Artan Doda, Enrico Sgaramella, Stefano Ticca, Filippo Veneziani Santonio, Riccardo Boccaletti
BACKGROUND: The use of intraoperative ultrasound (iUS) has increased in the last 15 years becoming a standard tool in many neurosurgical centers. Our aim was to assess the utility of routine use of iUS during various types of intracranial surgery. We reviewed our series to assess ultrasound visibility of different pathologies and iUS applications during the course of surgery. MATERIALS AND METHODS: This is a retrospective review of 162 patients who underwent intracranial surgery with assistance of the iUS guidance system (SonoWand)...
April 19, 2018: Acta Neurochirurgica
https://www.readbyqxmd.com/read/29665033/is-testicular-macrocalcification-a-risk-for-malignancy-tumor-development-on-ultrasonographic-follow-up-of-preexisting-intratesticular-macrocalcification
#8
Malene R Pedersen, Emily C Bartlett, Christian Brown, Søren R Rafaelsen, Maria E Sellars, Paul S Sidhu
Testicular macrocalcification is an uncommon finding when imaging the scrotum with ultrasonography (US). It is not normally a recognized risk factor for development of testicular malignancy, and patients are not usually offered follow-up US examinations or counseled for self-examination. This aspect is in distinction to patients with testicular microlithiasis (usually with an additional risk factor), who are offered follow-up on the assumption that microlithiasis is associated with malignancy. We report a series of 6 patients with predetermined testicular macrocalcification, with development of a malignancy on follow-up US...
April 17, 2018: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/29623580/management-and-consequences-of-postoperative-fluctuations-in-plasma-sodium-concentration-after-pediatric-brain-tumor-surgery-in-the-sellar-region-a-national-cohort-analysis
#9
R W J Kruis, A Y N Schouten-van Meeteren, M J J Finken, W Oostdijk, A S P van Trotsenburg, A M Boot, H L Claahsen-van der Grinten, E J van Lindert, K S Han, E W Hoving, E M C Michiels, H M van Santen
PURPOSE: Severe fluctuations in plasma sodium concentration and plasma osmolarity, including central diabetes insipidus (CDI), may have significant influence on postoperative morbidity and mortality after pediatric brain tumor surgery.The aim of this study was to describe the frequency, severity and neurological consequences of these fluctuations in pediatric brain tumor survivors. METHODS: A retrospective, multi-institutional chart review was conducted among all children who underwent brain tumor surgery in the sellar or suprasellar region in seven university hospitals in the Netherlands between January 2004 and December 2013...
April 5, 2018: Pituitary
https://www.readbyqxmd.com/read/29622503/multidisciplinary-management-of-an-intra-sellar-cavernous-hemangioma-case-report-and-review-of-the-literature
#10
S Chibbaro, H Cebula, M Ganau, A Gubian, J Todeschi, B Lhermitte, F Proust, G Noel
Extra-axial cavernous hemangiomas (ECH) are rare vascular lesions with a tendency to grow within the medial structures of the middle cranial fossa. This pathological entity lacks specific symptoms, and falls into the category of differential diagnosis of space occupying lesions in the cavernous sinus (CS) with or without sellar involvement, including those of tumoral, vascular and inflammatory nature. Of note, ECH can also be indolent, and is at times discovered incidentally during autopsy investigations. On radiological studies, ECH with sellar extension are frequently mistaken at first for pituitary adenomas...
April 2, 2018: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/29614125/the-prevalence-of-brain-abnormalities-in-boys-with-central-precocious-puberty-may-be-overestimated
#11
Jong Seo Yoon, Cheol Hwan So, Hae Sang Lee, Jung Sub Lim, Jin Soon Hwang
Brain magnetic resonance imaging (MRI) is routinely performed to identify brain lesions in boys with central precocious puberty (CPP). We investigated the prevalence of CPP in Korean boys and the necessity for routine brain MRI examinations. This retrospective cross-sectional study was conducted from April 2003 to December 2016 at a Korean university hospital. Among 151 boys who were diagnosed with CPP, the data of 138 boys who underwent sellar MRI were evaluated. The mean age of the study subjects was 9.51 ± 0...
2018: PloS One
https://www.readbyqxmd.com/read/29595045/the-endoscopic-surgical-resection-of-intrasellar-lesions-conserves-the-hormonal-function-a-negative-correlation-to-the-microsurgical-technique
#12
Stefan Linsler, Sebastian Senger, Renate Hero-Gross, Wolf-Ingo Steudel, Joachim Oertel
BACKGROUND: The endonasal endoscopic approach is still currently under investigation for sellar tumour surgery: a higher resection rate is to be expected and complications should be minimized. The authors report their surgical results of endonasal endoscopic neurosurgery with special focus on postoperative hypopituitarism in comparison to microsurgical procedures. METHODS: Sixty patients received endoscopic endonasal transsphenoidal procedures for sellar pathologies...
March 28, 2018: Journal of Neurosurgical Sciences
https://www.readbyqxmd.com/read/29588898/low-subfrontal-dural-opening-for-anterior-clinoid-meningioma
#13
Michael R Chicoine
Introduction  A variety of dural openings are described for frontal-temporal and cranio-orbital craniotomies. As with any surgical technique, the goal is to optimally and safely address the pathology, minimize normal anatomy disruption, and optimize postoperative recovery. This study reports a modified dural opening for frontal-temporal approaches which minimizes brain exposure while facilitating visualization for neoplastic and vascular lesions of the anterior clinoid, supra- and parasellar and adjacent regions...
April 2018: Journal of Neurological Surgery. Part B, Skull Base
https://www.readbyqxmd.com/read/29581015/suprasellar-hemangioblastoma-with-reversible-edema-like-change-along-the-optic-tract-a-case-report
#14
Yujiro Hattori, Shigeyuki Tahara, Osamu Yamada, Masahiro Yamaguchi, Eitaro Ishisaka, Akio Morita
BACKGROUND: Hemangioblastomas usually occur in the cerebellum, and are often a component of the von Hippel-Lindau disease. Edema-like changes along the optic tract are commonly observed in association with tumors in the sellar and suprasellar regions, such as craniopharyngiomas and pituitary adenomas. Here, we describe a case of sporadic suprasellar hemangioblastoma with edema-like changes along the optic tract that completely resolved after surgery CASE DESCRIPTION: The patient was a 28-year-old woman with failing vision and a bitemporal hemianopia...
March 23, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29572168/lymphocytic-hypophysitis-secondary-to-ruptured-rathke-s-cleft-cyst-case-report-and-literature-review
#15
Chengxian Yang, Huanwen Wu, Xinjie Bao, Renzhi Wang
BACKGROUND: Lymphocytic hypophysitis (LH) is a rare inflammatory lesion in sellar region. LH secondary to ruptured Rathke's cleft cyst (RCC) is even more rarely observed according to published case reports. The clinical characteristics, treatment strategies and prognosis of such lesions remain elusive. CASE DESCRIPTION: A 58-year-old Chinese woman was admitted to our hospital complaining of initial intermittent headache for 3 years and new development of polydipsia, polyuria, and binocular visual acuity decline for recent 4 months...
March 20, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29557987/endoscopic-removal-of-a-suprasellar-dermoid-cyst-in-a-pediatric-patient-a-case-report-and-review-of-the-literature
#16
Gokmen Kahilogullari, Fatih Yakar, Eyup Bayatli, Esra Erden, Cem Meco, Agahan Unlu
INTRODUCTION: Dermoid cysts (DCs) are unusual benign congenital intracranial tumors that typicallyarise in the midline and form as a result of abnormal sequestration of ectodermal cells during neural tubeformation. In all age groups, endoscopic approaches are preferable for the removal of sellar lesions. A 6-year-old girl with recurrent meningitis underwent endoscopic endonasal surgery forsellar DC. CONCLUSION: To the best of our knowledge, we present the first case of a suprasellar DC in a pediatric patient that was removed endoscopically...
March 20, 2018: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/29543211/-preoperative-and-postoperative-endocrine-disorders-associated-with-pituitary-stalk-injuries-caused-by-suprasellar-growing-tumors
#17
B A Kadashev, A N Konovalov, L I Astaf'eva, P L Kalinin, M A Kutin, I S Klochkova, D V Fomichev, O I Sharipov, D N Andreev
The pituitary stalk (PS) is a relatively thin bundle connecting the hypophyseal stalk to the pituitary gland; it consists of both axons of the hypothalamic nuclei (terminating in the neurohypophysis) and the system of portal vessels. Compression of the PS by a space-occupying lesion or its transection (forced or intended) during surgery may lead to the development of endocrine disorders: hypopituitarism, diabetes insipidus, and hyperprolactinemia. The modern literature lacks studies evaluating the severity of endocrine disorders depending on the PS condition before and after surgery...
2018: Zhurnal Voprosy Neĭrokhirurgii Imeni N. N. Burdenko
https://www.readbyqxmd.com/read/29539631/urgent-optic-nerve-decompression-via-an-endoscopic-endonasal-transsphenoidal-approach-for-craniopharyngioma-in-a-12-month-old-infant-a-case-report
#18
Teishiki Shibata, Motoki Tanikawa, Tomohiro Sakata, Mitsuhito Mase
Craniopharyngiomas are benign tumors and account for approximately 5.6-13% of all intracranial tumors in children. Diagnosis of pediatric craniopharyngioma is often delayed until the tumor becomes relatively large and manifests severe visual and/or endocrine disturbance. Endoscopic endonasal approaches have recently been introduced to surgery for craniopharyngioma. These techniques, however, have rarely been utilized in patients affected with craniopharyngioma as young as 1 year old. This report documents a 12-month-old male infant with sellar craniopharyngioma who presented with acute total vision loss...
March 14, 2018: Pediatric Neurosurgery
https://www.readbyqxmd.com/read/29524707/pediatric-case-of-xanthogranuloma-in-sellar-region-presenting-visual-disturbance-successfully-treated-by-endoscopic-endonasal-surgery
#19
Fumihiko Nishimura, Young-Su Park, Yasushi Motoyama, Ichiro Nakagawa, Shuichi Yamada, Hiroyuki Nakase
BACKGROUND: Xanthomatous pituitary diseases rarely occur in childhood. We report a rare pediatric case of a xanthogranuloma that developed in the sellar region resulting in visual disturbance that was successfully treated by endoscopic endonasal surgery. CASE DESCRIPTIONS: A 13-year-old boy came to us with a headache and visual disturbance that had occurred 1 month prior. Clinical examination findings showed that he was alert with signs of bitemporal hemianopsia, an endocrinological examination showed partial hypopituitarism, and brain magnetic resonance imaging (MRI) revealed a cystic mass in the sellar turcica compressing the optic apparatus...
March 7, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29509940/multiplexed-immunofluorescence-reveals-potential-pd-1-pd-l1-pathway-vulnerabilities-in-craniopharyngioma
#20
Shannon Coy, Rumana Rashid, Jia-Ren Lin, Ziming Du, Andrew M Donson, Todd C Hankinson, Nicholas K Foreman, Peter E Manley, Mark W Kieran, David A Reardon, Peter K Sorger, Sandro Santagata
Background: Craniopharyngiomas are neoplasms of the sellar/parasellar region that are classified into adamantinomatous (ACP) and papillary (PCP) subtypes. Surgical resection of craniopharyngiomas is challenging, and recurrence is common, frequently leading to profound morbidity. BRAF V600E mutations render PCP susceptible to BRAF/MEK inhibitors, but effective targeted therapies are needed for ACP. We explored the feasibility of targeting the PD-1/PD-L1 immune checkpoint pathway in ACP and PCP...
March 2, 2018: Neuro-oncology
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