Yunchuang Sun, Luhua Wei, Fan Li, Chen Ling, Fei Zhai, Yunfeng Lv, Hong Zhou, Cheng Zhang, Jing Ma, Jing Chen, Wei Sun, Zhaoxia Wang
INTRODUCTION: The reverse dipping blood pressure (BP) pattern is very common in α-synucleinopathies. We aimed to explore the associations of sleep-related variables with abnormal BP circadian rhythms in Parkinson's disease (PD) and multiple system atrophy (MSA). METHODS: A total of 126 patients, 76 with PD and 50 with MSA, were included. All participants underwent ambulatory BP monitoring and full-night polysomnography (PSG). We analyzed abnormal dipping patterns and sleep-related parameters, including moderate to severe obstructive sleep apnea (OSA), rapid eye movement behavior disorder (RBD), average oxygen saturation (SaO2 %), lowest SaO2 %, duration of SaO2 % <90%, and apnea-hypopnea index (AHI)...
February 12, 2024: Parkinsonism & related Disorders