Ludovico Messineo, Scott Sands, Christopher Schmickl, Gonzalo Labarca, Wen-Hsin Hu, Neda Esmaeili, Daniel Vena, Laura Gell, Nicole Calianese, Atul Malhotra, Daniel J Gottlieb, Andrew Wellman, Susan Redline, Ali Azarbarzin
BACKGROUND: Obstructive sleep apnea is associated with increased blood pressure (BP). Obstructive sleep apnea treatment reduces BP with substantial variability, not explained by the apnea-hypopnea index, partly due to inadequate characterization of obstructive sleep apnea's physiological consequences, such as oxygen desaturation, cardiac autonomic response, and suboptimal treatment efficacy. We sought to examine whether a high baseline heart rate response (ΔHR), a marker of high cardiovascular risk in obstructive sleep apnea, predicts a larger reduction in posttreatment systolic BP (SBP)...
March 20, 2024: Hypertension