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Mucosa-Associated Lymphoid Tissue Lymphoma

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https://www.readbyqxmd.com/read/28911036/high-fat-diet-induced-obesity-upregulates-the-expression-of-lymphoid-chemokines-and-promotes-the-formation-of-gastric-lymphoid-follicles-after-helicobacter-suis-infection
#1
Wen-Jun Zhao, Zi-Bin Tian, Shan-Shan Yao, Ya-Nan Yu, Cui-Ping Zhang, Xiao-Yu Li, Tao Mao, Xue Jing, Xue-Li Ding, Ruo-Ming Yang, Ya-Qian Liu, Shuai-Qing Zhang, Lin Yang
Helicobacter suis colonizes the stomachs of a variety of animals, including humans, and is more likely than other Helicobacter species to induce gastric mucosa-associated lymphoid tissue lymphoma. Obesity is a low-grade chronic inflammatory state in which the induction of a chemokine network contributes to a variety of diseases. However, the effect of obesity on the development of gastric MALT in the presence of H. suis infection remains unclear. Here, we reveal that high-fat-diet-induced obesity upregulates the expression of lymphoid chemokines in the stomach and accelerates the H...
November 30, 2017: Pathogens and Disease
https://www.readbyqxmd.com/read/28910872/-pathologic-subtyping-of-primary-lymphoma-of-breast-and-prognostic-analysis
#2
Z J Zhou, J L Xie, P Wei, X G Zhou
Objective: To investigate the pathological types and prognostic factors of primary lymphoma of breast (PLB). Methods: The clinical pathological data of 115 cases of PLB during October 2006 to October 2016 were retrospectively analyzed, and the basic clinical and pathological data, pathology types and the immunohistochemical slides by EliVision two-step method for staining were summarized. Results: Almost all the patients were women (113/115), and the median age was 52 years old (range: 27 to 81 years old). The main symptom was painless progressive mass in breast...
September 8, 2017: Zhonghua Bing Li Xue za Zhi Chinese Journal of Pathology
https://www.readbyqxmd.com/read/28910871/-mucosa-associated-lymphoid-tissue-lymphoma-in-children-and-adolescents-a-clinicopathologic-study-of-5-cases
#3
J Hu, J L Xie, Z J Zhou, X G Zhou
Objective: To investigate the pathological features and clinical manifestations of mucosa-associated lymphoid tissue (MALT) lymphoma in children and adolescents. Methods: Five cases of MALT lymphoma in children were investigated by morphology and immunophenotyping along with clinical follow-up. Results: Five cases of MALT lymphoma occurred in the antrum, orbit, parotid gland and nasopharynx. All patients had no B symptoms and only one patient showed a local mass with ulcer. One case presented with cervical lymph node enlargement, and 4 cases showed no evidence of lymphadenopathy...
September 8, 2017: Zhonghua Bing Li Xue za Zhi Chinese Journal of Pathology
https://www.readbyqxmd.com/read/28902730/dural-malt-lymphoma-detected-by-11c-methionine-pet-ct
#4
Salvatore Annunziata, Annarosa Cuccaro, Carmelo Caldarella, Stefan Hohaus
A 53-year-old man had a diagnosis of mucosa-associated lymphoid tissue lymphomas of the dura in the left tentorium. The patient underwent whole-body F-FDG PET/CT and C-methionine PET/CT in order to complete the staging of dural mucosa-associated lymphoid tissue lymphoma. C-methionine uptake was detected in multiple meningeal sites, including left tentorium, with no significant FDG uptake in the same regions.
September 11, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/28894065/-mucosa-associated-lymphoid-tissue-lymphoma-in-the-thymus-report-of-a-case
#5
Kazuyoshi Shimada, Masaki Kawamura
A 64-years-old woman with chronic thyroiditis was refered to our hospital because of anterior mediastinum tumors identified by chest computed tomography (CT). The lesions with increased fluoro-2-deoxy-D-glucose (FDG) uptake was noted by CT and positron emission tomography (PET). Extended thymo-thymectomy was performed, and the tumors was completely resected. Pathologically, the tumors were diagnosed as mucosa-associated lymphoid tissue( MALT) lymphoma of the thymus. Postoperative chemotherapy was not performed and the patient has been well for 4 years without recurrence...
September 2017: Kyobu Geka. the Japanese Journal of Thoracic Surgery
https://www.readbyqxmd.com/read/28891127/helicobacter-pylori-gastric-cancer-and-other-gastrointestinal-malignancies
#6
REVIEW
Marino Venerito, Riccardo Vasapolli, Theodore Rokkas, Jean-Charles Delchier, Peter Malfertheiner
In a retrospective study performed in California, U.S.A., ca. 3% of patients with gastric intestinal metaplasia (GIM) developed gastric cancer (GC) within a median time period of 4.6 years after diagnosis of GIM. This observation stresses the importance of targeted surveillance even in regions with a low GC prevalence. Patients with alcoholic liver disease as well as survivors of colorectal and lobular breast cancer were found to be at increased risk of secondary GC. A population-based Chinese study confirmed "serologic biopsy" as a useful screening tool for stratifying the individual risk of developing GC...
September 2017: Helicobacter
https://www.readbyqxmd.com/read/28883273/regression-of-uterine-cervical-diffuse-large-b-cell-lymphoma-transformed-from-mucosa-associated-lymphoid-tissue-lymphoma-subsequent-to-chlamydia-trachomatis-eradication
#7
Toshitaka Mutoh, Hiroshi Takatsuki, Kiyohito Mannoji, Kyoko Kawamura, Naofumi Okura, Koichi Ohshima
A 37-year-old-woman was referred to our center after her uterine cervix health screening presented abnormal findings. We performed a biopsy of the uterine cervix to examine for cervical dysplasia, and diagnosed a diffuse large B-cell lymphoma transformed from mucosa-associated lymphoid tissue (MALT) lymphoma of the cervix. The patient presented with concurrent chlamydial cervicitis and received eradication therapy for Chlamydia trachomatis. Four months later, the CD20 positive abnormal lymphocyte disappeared and complete remission was achieved...
2017: [Rinshō Ketsueki] the Japanese Journal of Clinical Hematology
https://www.readbyqxmd.com/read/28882576/endoscopic-features-and-clinical-outcomes-of-colorectal-mucosa-associated-lymphoid-tissue-lymphoma
#8
Min Kyung Jeon, Hoonsub So, Jooryung Huh, Hee Sang Hwang, Sung Wook Hwang, Sang Hyoung Park, Dong-Hoon Yang, Kee Don Choi, Byong Duk Ye, Seung-Jae Myung, Suk-Kyun Yang, Jeong-Sik Byeon
BACKGROUND & AIMS: Colorectal mucosa-associated lymphoid tissue (MALT) lymphoma is a rare disease. The purpose of this study was to investigate the clinical and endoscopic features of colorectal MALT lymphoma. METHODS: Patients diagnosed with colorectal MALT lymphoma at Asan Medical Center from 2002 to 2016 were eligible. Medical records were reviewed to investigate clinical features and treatment outcomes. Endoscopic pictures were assessed to characterize the endoscopic features of colorectal MALT lymphoma...
September 4, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28879864/linked-color-imaging-technology-for-diagnosis-of-gastric-mucosa-associated-lymphoid-tissue-lymphoma
#9
Pei Deng, Min Min, Cui-Yun Ma, Yan Liu
No abstract text is available yet for this article.
September 7, 2017: Chinese Medical Journal
https://www.readbyqxmd.com/read/28875091/demographics-of-head-and-neck-cancer-patients-a-single-institution-experience
#10
George S Stoyanov, Martina Kitanova, Deyan L Dzhenkov, Peter Ghenev, Nikolay Sapundzhiev
Introduction Head and neck cancer (HNC) comprises a diverse group of oncological entities, originating from various tissue types and organ localizations, situated in the topographical regions of the head and neck (H&N). This single institution retrospective study was aimed at establishing the HNC patient demographics and categorizing the individual incidence of H&N malignancies, regarding their organ of origin and main histopathological type. Materials and methods All histologically verified cases of HNC from a single tertiary referral center were reviewed in a descriptive retrospective manner...
July 2, 2017: Curēus
https://www.readbyqxmd.com/read/28871587/primary-pulmonary-malt-lymphoma-presenting-as-non-resolving-pneumonia
#11
Asma Iftikhar, Albert Magh, Muhammed Azaz Cheema, Sarah Thappa, Sonu Sahni, Stephen Karbowitz
Primary lung lymphoma (PLL) is a rare unilateral or bilateral lung disorder that is challenging to diagnose solely based on clinical and radiological presentation. PLL may be misdiagnosed as pneumonia or a lung tumor due to non-specific findings. PLL is most frequently a mucosa-associated lymphoid tissue (MALT) lymphoma, a type of extranodal low-grade B-cell lymphoma most commonly discovered in the gastrointestinal tract. PLL should be considered in the differential diagnosis of non-resolving pneumonias. Herein we present a case of an 84-year-old patient discovered to have a primary pulmonary MALT lymphoma presenting as a non-resolving pneumonia causing a clinical challenge...
2017: Advances in Respiratory Medicine
https://www.readbyqxmd.com/read/28834011/protective-efficacy-of-a-hydroxy-fatty-acid-against-gastric-helicobacter-infections
#12
Hidenori Matsui, Tetsufumi Takahashi, Somay Y Murayama, Marina Kawaguchi, Koichi Matsuo, Masahiko Nakamura
BACKGROUND: We have previously revealed that omega-3 polyunsaturated fatty acids can prevent Helicobacter pylori infection by blocking the futalosine pathway, an alternative route for menaquinone (MK) biosynthesis. MATERIALS AND METHODS: 1, Different H. pylori strains were grown in liquid media supplemented with linoleic acid, an omega-6 fatty acid, or its 10-hydroxy derivative, 10-hydroxy-cis-12-octadecenoic acid (HYA), in the presence or absence of MK. The bacterial numbers in the media were estimated by plating; 2, C57BL/6NCrl mice received drinking water supplemented with different fatty acids starting from 1 week before infection with H...
August 22, 2017: Helicobacter
https://www.readbyqxmd.com/read/28833354/immunohistochemical-expression-of-cereblon-and-mum1-as-potential-predictive-markers-of-response-to-lenalidomide-in-extranodal-marginal-zone-b-cell-lymphoma-of-the-mucosa-associated-lymphoid-tissue-malt-lymphoma
#13
Barbara Kiesewetter, Ingrid Simonitsch-Klupp, Christoph Kornauth, Werner Dolak, Julius Lukas, Marius E Mayerhoefer, Markus Raderer
Lenalidomide is an active agent for the treatment of MALT lymphoma. Recently, high expression levels of cereblon (CRBN) and MUM1 have been associated with better response rates in multiple myeloma treated with lenalidomide. However, there are no data on CRBN and MUM1 expression in MALT lymphoma. In the current study, we have systematically investigated a potential correlation of CRBN/MUM1 immunohistochemical expression and response to lenalidomide-based therapy in a series of 46 patients with MALT lymphoma treated at the Medical University Vienna 2009 to 2014...
August 22, 2017: Hematological Oncology
https://www.readbyqxmd.com/read/28831450/colonic-mucosa-associated-lymphoid-tissue-lymphoma-presented-as-multiple-polyposis-at-colonoscopy-in-a-nigerian-man-case-report-of-a-rare-occurrence-and-brief-review-of-literature
#14
Aderemi Oluyemi, Nicholas Awolola
No abstract text is available yet for this article.
August 2017: Journal of Global Oncology
https://www.readbyqxmd.com/read/28830898/primary-gastric-burkitt-lymphoma-a-rare-cause-of-life-threatening-haematemesis
#15
Fares Ayoub, Justin J Forde, Niraj Patel, Merry Markham
Lymphomas are the second most common gastric malignancy following gastric adenocarcinoma. The majority of gastric lymphomas are either mucosa-associated lymphoid tissue lymphomas or diffuse large B-cell lymphomas. Primary gastric Burkitt lymphoma is a subtype of non-Hodgkin's lymphoma and represents an aggressive and rare malignancy with only a small number of cases reported worldwide. Clinical and radiological presentation is non-specific and mimics other gastric lymphomas. Diagnosis is established with pathological evaluation...
August 22, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28830222/pulmonary-mucosa-associated-lymphoid-tissue-lymphoma-18f-fdg-pet-ct-and-ct-findings-in-28-patients
#16
Domenico Albano, Andrea Borghesi, Giovanni Bosio, Mattia Bertoli, Roberto Maroldi, Raffaele Giubbini, Francesco Bertagna
OBJECTIVE: The aim of the study was to evaluate the computed tomography (CT) and fluorine-18-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) imaging findings of lung mucosa associated lymphoid tissue (MALT) lymphoma. METHODS: Twenty eight patients with histologically-confirmed pulmonary MALT lymphoma who underwent a chest CT and 18F-FDG PET/CT for staging were retrospectively analyzed. The CT images were evaluated to determine morphological pattern of appearance, laterality, localization, number, size, presence of thoracic lymphadenopaties and secondary/combined findings...
August 22, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28815477/radiotherapy-for-mucosa-associated-lymphoid-tissue-malt-lymphoma-of-the-rectum-a-case-report
#17
Toyokazu Hayakawa, Tetsuo Nonaka, Nobutaka Mizoguchi, Yasuhito Hagiwara, Shino Shibata, Rika Sakai, Norisuke Nakayama, Tomoyuki Yokose, Yuko Nakayama
Extra-nodal mucosa-associated lymphoid tissue (MALT) lymphoma is frequently involved with the upper gastrointestinal tract, but rarely involved with the rectum. We report a case of rectal MALT lymphoma treated by radiotherapy (RT) alone. A 74-year-old woman with lower abdominal pain was diagnosed with MALT lymphoma by endoscopic mucosal resection (EMR). She was diagnosed as stage IE (Ann Arbor) MALT lymphoma by diagnostic work-up and review of EMR specimens. Definitive RT was performed with curative intent, totaling 30 Gy in 15 fractions...
August 16, 2017: Clinical Journal of Gastroenterology
https://www.readbyqxmd.com/read/28808514/nodular-pulmonary-amyloidosis-with-primary-pulmonary-malt-lymphoma-masquerading-as-metastatic-lung-disease
#18
Sunil Upadhaya, Mohd Baig, Basim Towfiq, Samer Al Hadidi
Nodular pulmonary amyloidosis is a very rare form of localized amyloidosis involving the lung, with very little known about its nature. It is usually associated with indolent B cell lymphoproliferative disorder and also connective tissue disorders. No definite treatment guideline exists. Many patients respond to chemotherapy with low risk of progression and a 'wait and watch' strategy is also considered a valid treatment option. In this report the authors present a case of nodular pulmonary amyloidosis with pulmonary mucosa associated lymphoid tissue (MALT) lymphoma that presented with features of metastatic malignant disease and after definitive diagnosis decided not to undergo treatment...
July 2017: Journal of Community Hospital Internal Medicine Perspectives
https://www.readbyqxmd.com/read/28801448/long-term-results-of-a-phase-ii-study-of-rituximab-and-bendamustine-for-mucosa-associated-lymphoid-tissue-lymphoma
#19
Antonio Salar, Eva Domingo-Domenech, Carlos Panizo, Concepción Nicolás, Joan Bargay, Ana Muntañola, Miguel Canales, José Luis Bello, Juan Manuel Sancho, José Francisco Tomás, María José Rodríguez, Javier Peñalver, Carlos Grande, José Javier Sánchez-Blanco, Luis Palomera, Reyes Arranz, Eulogio Conde, Mar García, Juan Fernando García, Dolores Caballero, Carlos Montalbán
No abstract text is available yet for this article.
August 11, 2017: Blood
https://www.readbyqxmd.com/read/28765954/in%C3%A2-vitro-reconstitution-of-interactions-in-the-card9-signalosome
#20
Jin Hee Park, Jae Young Choi, Mir Faisal Mustafa, Hyun Ho Park
The caspase-associated recruitment domain (CARD)‑containing protein 9 (CARD9) signalosome is composed of CARD9, B‑cell CLL/lymphoma 10 (BCL10) and mucosa‑associated lymphoid tissue lymphoma translocation protein 1 (MALT1). The CARD9 signalosome has been reported to exert critical functions in the immunoreceptor tyrosine‑based activation motif‑coupled receptor‑mediated activation of myeloid cells, through nuclear factor‑κB pathways during innate immunity processes. During CARD9 signalosome assembly, BCL10 has been revealed to function as an adaptor protein and to interact with CARD9 via CARD‑CARD interactions; BCL10 also interacts with MALT1 via its C‑terminal Ser/Thr‑rich region and the first immunoglobulin domain of MALT1...
October 2017: Molecular Medicine Reports
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