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https://www.readbyqxmd.com/read/28180206/multiple-cardiac-complications-after-adjuvant-therapy-for-breast-cancer-the-importance-of-echocardiography-a-case-report-and-review-of-the-literature
#1
Adriana Luminita Gurghean, Ilinca Savulescu-Fiedler, Anca Mihailescu
Cardiovascular complications induced by adjuvant cancer therapies may become symptomatic after many years, being responsible for increased morbidity and mortality in long-term survivors. We report a case of a 54-year old female admitted for severe heart failure induced by myocardial and valvular damage after postoperative adjuvant therapy for left breast cancer 6 years ago. Her recent history revealed nonST elevation myocardial infarction in the absence of significant cardiovascular risk factors. Transthoracic echocardiography, tissue Doppler imaging and speckle-tracking imaging revealed severe biventricular systolic dysfunction, severe mitral and tricuspid regurgitation and severe pulmonary hypertension...
January 31, 2017: Medical Ultrasonography
https://www.readbyqxmd.com/read/28065613/anca-negative-churg-strauss-syndrome-presenting-as-acute-multiple-cerebral-infarcts-a-case-report
#2
Klearchos Psychogios, Ilias Evmorfiadis, Spyros Dragomanovits, Athanasios Stavridis, Konstantinos Takis, Loukas Kaklamanis, Stathis Pantelis
Eosinophilic granulomatosis with polyangiitis (EGPA, previously named Churg-Strauss syndrome) is a form of necrotizing vasculitis occurring in patients with asthma and eosinophilia. Ischemic stroke is a relatively rare complication of the disease. We report a case of a 63-year-old woman with multiple embolic infarcts, hypereosinophilia (for >7 years), and skin rash. Elevated cardiac enzymes and cardiac magnetic resonance imaging were consistent with endomyocarditis. The simultaneous presence of history of asthma, sinusitis, hypereosinophilia, and vasculitis led to the diagnosis of EGPA...
January 5, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/28002315/a-case-report-and-literature-review-of-churg-strauss-syndrome-presenting-with-myocarditis
#3
REVIEW
Lu Qiao, Dengfeng Gao
BACKGROUND: Churg-Strauss syndrome (CSS) is a multisystem disorder characterized by asthma, prominent peripheral blood eosinophilia, and vasculitis signs. CASE SUMMARY: Here we report a case of CSS presenting with acute myocarditis and heart failure and review the literature on CSS with cardiac involvement. A 59-year-old man with general fatigue, numbness of limbs, and a 2-year history of asthma was admitted to the department of orthopedics. Eosinophilia, history of asthma, lung infiltrates, peripheral neurological damage, and myocarditis suggested the diagnosis of CSS...
December 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27931223/pattern-and-prognostic-value-of-cardiac-involvement-in-patients-with-late-onset-pompe-disease-a-comprehensive-cardiovascular-magnetic-resonance-approach
#4
Matthias Boentert, Anca Florian, Bianca Dräger, Peter Young, Ali Yilmaz
BACKGROUND: Pompe disease is an autosomal recessive disorder caused by deficiency of the lysosomal α-1,4-glucosidase leading to accumulation of glycogen in target tissues with progressive organ failure. While the early infantile-onset form is characterized by early severe hypertrophic cardiomyopathy with cardiac and respiratory failure, clinically relevant cardiomyopathy seems to be uncommon in patients with late-onset Pompe disease, and the prevalence and nature of myocardial abnormalities are still to be clarified...
December 7, 2016: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/27885316/bartonella-endocarditis-and-pauci-immune-glomerulonephritis-a-case-report-and-review-of-the-literature
#5
REVIEW
Jillian E Raybould, Alison L Raybould, Megan K Morales, Misbah Zaheer, Michael S Lipkowitz, Joseph G Timpone, Princy N Kumar
Among culture-negative endocarditis in the United States, Bartonella species are the most common cause, with Bartonella henselae and Bartonella quintana comprising the majority of cases. Kidney manifestations, particularly glomerulonephritis, are common sequelae of infectious endocarditis, with nearly half of all Bartonella patients demonstrating renal involvement. Although a pauci-immune pattern is a frequent finding in infectious endocarditis-associated glomerulonephritis, it is rarely reported in Bartonella endocarditis...
September 2016: Infectious Diseases in Clinical Practice: IDCP
https://www.readbyqxmd.com/read/27882604/the-dog-bone-technique-a-novel-easy-and-safe-catheter-maneuver-for-aortic-arch-and-coarctation-stenting
#6
Marinos Kantzis, Anja Lehner, Kai Thorsten Laser, Anca Racolta, Radka Vcasna, Marcus Fischer, Deniz Kececioglu, Nikolaus A Haas
BACKGROUND: Various techniques are described to facilitate stable stent implantation in aortic arch stenosis or coarctation. We describe an alternative technique, which due to its unique appearance during stent implantation, we have named "Dog Bone Technique" (DBT). TECHNIQUE: The stent/balloon assembly is placed across the stenosis, the long sheath is retrieved to uncover the distal 20-50% of the stent. The balloon is inflated with the pressure inflator just to expand slightly the stent...
February 2017: Journal of Interventional Cardiology
https://www.readbyqxmd.com/read/27714710/cardiac-manifestations-in-antineutrophil-cytoplasmic-autoantibody-anca-associated-vasculitides
#7
Katarzyna Życińska, Anna Borowiec
No abstract text is available yet for this article.
2016: Kardiologia Polska
https://www.readbyqxmd.com/read/27666870/effects-of-thyroid-hormone-withdrawal-on-natriuretic-peptides-during-radioactive-iodine-therapy-in-female-patients-with-differentiated-thyroid-cancer
#8
Adina Elena Stanciu, Anca Elena Hurduc, Marcel Marian Stanciu
OBJECTIVE: We aimed to investigate the effects of thyroid hormone withdrawal on N-terminal prohormone forms of atrial natriuretic peptide (NT-proANP) and brain natriuretic peptide (NT-proBNP) during radioiodine therapy in female patients with differentiated thyroid cancer (DTC). METHODS: Serum concentrations of thyroid-stimulating hormone (TSH), free triiodothyronine (FT3), NT-proANP and NT-proBNP were measured in 51 female patients with DTC (48.7 ± 4.2 years) at three time-points: day of radioiodine therapy (t1 - under acute hypothyroidism), 5 days after radioiodine (t2 - under acute hypothyroidism) and 3 months after radioiodine (t3 - under TSH suppression)...
December 2016: Scandinavian Journal of Clinical and Laboratory Investigation
https://www.readbyqxmd.com/read/27611916/cardiac-involvement-in-patients-with-rheumatic-disorders-data-of-the-rheu-m-a-r-study
#9
Simon Greulich, Daniel Kitterer, Reto Kurmann, Joerg Henes, Joerg Latus, Steffen Gloekler, Andreas Wahl, Sebastian J Buss, Hugo A Katus, Marco Bobbo, Massimo Lombardi, Maik Backes, Hannah Steubing, Pascal Schepat, Niko Braun, M Dominik Alscher, Udo Sechtem, Heiko Mahrholdt
BACKGROUND: The diagnosis of cardiac involvement in rheumatic disorders is challenging due to its varying clinical presentation. Since clinical consequences range from immediate treatment changes to adverse long-term outcome, individual risk stratification is of great clinical interest. Primary aim was to evaluate the prevalence of cardiac involvement in patients with different rheumatic disorders using late gadolinium enhancement-cardiac magnetic resonance imaging (LGE-CMR). In addition, we sought to investigate if different rheumatic disorders would demonstrate different LGE patterns...
December 1, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27591039/anca-negative-eosinophilic-granulomatosis-with-polyangitis-egpa-manifesting-as-a-large-intracardiac-thrombus-and-glomerulonephritis-with-angionecrosis
#10
Yuichi Saito, Sho Okada, Nobusada Funabashi, Yoshio Kobayashi
A 59-year-old woman with a history of bronchial asthma presented with a prolonged fever and eosinophilia. There was transient proteinuria and troponin level was elevated. Antineutrophil cytoplasmic antibody was negative and she did not fulfil criteria for eosinophilic granulomatosis with polyangitis (EGPA). Echocardiography showed a large apical mass in the left ventricle, but there was no systolic dysfunction, local asynergy or ventricular remodelling. On MRI, apical mass was compatible with a thrombus and endocardial region was diffusely damaged...
September 2, 2016: BMJ Case Reports
https://www.readbyqxmd.com/read/27486321/remote-magnetic-targeting-of-iron-oxide-nanoparticles-for-cardiovascular-diagnosis-and-therapeutic-drug-delivery-where-are-we-now
#11
REVIEW
Michael Bietenbeck, Anca Florian, Cornelius Faber, Udo Sechtem, Ali Yilmaz
Magnetic resonance imaging (MRI) allows for an accurate assessment of both functional and structural cardiac parameters, and thereby appropriate diagnosis and validation of cardiovascular diseases. The diagnostic yield of cardiovascular MRI examinations is often increased by the use of contrast agents that are almost exclusively based on gadolinium compounds. Another clinically approved contrast medium is composed of superparamagnetic iron oxide nanoparticles (IONs). These particles may expand the field of contrast-enhanced cardiovascular MRI as recently shown in clinical studies focusing on acute myocardial infarction (AMI) and atherosclerosis...
2016: International Journal of Nanomedicine
https://www.readbyqxmd.com/read/27449465/a-rare-case-of-florid-antineutrophil-cytoplasmic-autoantibody-associated-vasculitis-involving-both-atrioventricular-valves
#12
Habib Khan, Sanjay Chaubey, Rynda Nitiahpapand, Jatin Desai
Cardiac involvement is rare in antineutrophil cytoplasmic autoantibody (ANCA)-associated systemic vasculitis but can involve aortic and mitral valves. We present an unusual case of a 65-year-old woman who presented 16 years after an aortic valve replacement with severe mitral regurgitation with ACNA-associated vasculitis. The extensive nature of the pathologic condition, which extended to the tricuspid valve, prevented the replacement of the mitral valve during a surgical procedure. This is a rare case in which florid valvulopathy was observed in association with vasculitis...
August 2016: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/27370964/granulomatosis-with-polyangiitis-mimicking-infective-endocarditis-in-an-adolescent-male
#13
REVIEW
Giulia Camilla Varnier, Neil Sebire, Georgi Christov, Despina Eleftheriou, Paul A Brogan
Granulomatosis with polyangiitis (GPA) is a rare but serious small vessel vasculitis with heterogeneous clinical presentation ranging from mainly localised disease with a chronic course, to a florid, acute small vessel vasculitic form characterised by severe pulmonary haemorrhage and/or rapidly progressive vasculitis or other severe systemic vasculitic manifestations. Cardiac involvement is, however, uncommon in the paediatric population. We report a case of a 16-year-old male who presented with peripheral gangrene and vegetation with unusual location on the supporting apparatus of the tricuspid valve, initially considered to have infective endocarditis but ultimately diagnosed with GPA...
September 2016: Clinical Rheumatology
https://www.readbyqxmd.com/read/27316915/french-intensive-care-society-international-congress-r%C3%A3-animation-2016
#14
(no author information available yet)
No abstract text is available yet for this article.
June 2016: Annals of Intensive Care
https://www.readbyqxmd.com/read/27279960/-a-rare-mode-of-revelation-of-wegener-s-granulomatosis-myocarditis-associated-with-a-fibroblastic-endocarditis
#15
Salim Arous, Ilham Bensahi, Malika Noureddine, Rachida Habbal
We report, through this observation, a rare case of Wegener's disease revealed by myocarditis associated with fibroblastic endocarditis. The patient was initially admitted to hospital with global heart failure. The ECG showed atrial flutter rhythm disorder. Echocardiographic examination revealed non-dilated left ventricle with severe dysfunction and positive troponin dosage. Severe renal failure was discovered fortuitously and required hemodialysis. It was associated with an inflammatory anaemia confirmed by serum ferritin and myelogram...
2016: Pan African Medical Journal
https://www.readbyqxmd.com/read/27259333/the-antioxidant-immunomodulatory-and-anti-inflammatory-activities-of-spirulina-an-overview
#16
REVIEW
Qinghua Wu, Lian Liu, Anca Miron, Blanka Klímová, Dan Wan, Kamil Kuča
Spirulina is a species of filamentous cyanobacteria that has long been used as a food supplement. In particular, Spirulina platensis and Spirulina maxima are the most important. Thanks to a high protein and vitamin content, Spirulina is used as a nutraceutical food supplement, although its other potential health benefits have attracted much attention. Oxidative stress and dysfunctional immunity cause many diseases in humans, including atherosclerosis, cardiac hypertrophy, heart failure, and hypertension. Thus, the antioxidant, immunomodulatory, and anti-inflammatory activities of these microalgae may play an important role in human health...
August 2016: Archives of Toxicology
https://www.readbyqxmd.com/read/27179547/identification-of-two-novel-lamp2-gene-mutations-in-danon-disease
#17
Beáta Csányi, Anca Popoiu, Lidia Hategan, Zoltán Hegedűs, Viktória Nagy, Katalin Rácz, Márta Hőgye, László Sághy, Béla Iványi, Miklós Csanády, Tamás Forster, Róbert Sepp
BACKGROUND: Danon disease is a rare X-linked inherited disorder characterized by massive left ventricular hypertrophy, skeletal muscle dystrophy, and mental retardation. The disease is caused by mutations in the LAMP2 gene encoding for lysosome-associated membrane protein-2. METHODS: Two young male patients with hypertrophic cardiomyopathy, characterized by marked, concentric left ventricular hypertrophy, elevated levels of creatine kinase, and manifest limb-girdle muscular dystrophy in 1 case, were investigated...
March 4, 2016: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/27169468/prevalence-of-osteo-renal-impairment-in-the-romanian-hiv-cohort
#18
Anca Streinu-Cercel, Oana Săndulescu, Gabriela Ceapraga, Daniela Manolache, Monica Andreea Stoica, Liliana Lucia Preoțescu, Adrian Streinu-Cercel
BACKGROUND: The Romanian HIV cohort has certain particularities that render it unique in Europe. We have performed a study to evaluate the prevalence of bone and kidney impairment in this particular group of HIV-infected patients. METHODS: We performed dual-energy X-ray absorptiometry (DXA) evaluation of the lumbar vertebrae and the femur, as well as laboratory tests including standard serum panels, bone-related markers and urinalysis in patients from the Romanian HIV cohort...
2016: BMC Infectious Diseases
https://www.readbyqxmd.com/read/27150296/identification-of-cardiomyopathy-associated-circulating-mirna-biomarkers-in-patients-with-muscular-dystrophy-using-a-complementary-cardiovascular-magnetic-resonance-and-plasma-profiling-approach
#19
Svetlana Becker, Anca Florian, Alexandru Patrascu, Sabine Rösch, Johannes Waltenberger, Udo Sechtem, Matthias Schwab, Elke Schaeffeler, Ali Yilmaz
BACKGROUND: Duchenne and Becker muscular dystrophy (DMD and BMD) are X-chromosomal recessive neuromuscular disorders that are caused by mutations in the dystrophin gene and characterized by cardiac involvement. Circulating microRNAs (miRNAs) have been proposed as diagnostic biomarkers for various cardiovascular diseases. However, circulating miRNAs reflecting the presence and/or disease severity of cardiac involvement in DMD/BMD patients have not been described so far. METHODS: Sixty-three male patients with known MD and 26 age-matched healthy male controls were prospectively enrolled...
2016: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/27148677/deceleration-and-acceleration-capacities-in-risk-stratification-for-arrhythmias-in-patients-with-chronic-obstructive-pulmonary-disease
#20
Catalin A Buzea, Gheorghe A Dan, Anca R Dan, Caterina Delcea, Marius I Balea, Daniela Gologanu, Raluca A Popescu, Mihaela Dobranici
BACKGROUND: Patients with chronic obstructive pulmonary disease (COPD) have an increased risk for both supraventricular and ventricular arrhythmias. Autonomic dysregulation may be responsible for the development of arrhythmias in these patients, and its analysis could be useful for identifying those at high risk for arrhythmias. STUDY QUESTION: Our purpose is to analyze the role of acceleration capacity (AC) and deceleration capacity (DC), novel markers of the autonomic balance, as potential arrhythmic risk predictors in patients with COPD...
January 2017: American Journal of Therapeutics
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