keyword
MENU ▼
Read by QxMD icon Read
search

Vaccine derived poliovirus

keyword
https://www.readbyqxmd.com/read/29126173/immunogenicity-of-different-routine-poliovirus-vaccination-schedules-a-randomized-controlled-trial-karachi-pakistan
#1
Ali F Saleem, Ondrej Mach, Mohammad T Yousafzai, Asia Khan, William C Weldon, M Steven Oberste, Syed S Zaidi, Muhammad M Alam, Farheen Quadri, Roland W Sutter, Anita K M Zaidi
Background: We assessed immunity against polioviruses induced with new Pakistani immunization schedule and compared it with alternative immunization schedules. Methods: Newborns were randomized to receive one of the following vaccination schedules, administered at birth, 6, 10, and 14 weeks of age. Arm A: 4x IPV; Arm B: 4x bOPV; Arm C and D: bOPV, bOPV, bOPV, bOPV+ inactivated poliovirus vaccine (IPV); Arm E: 4x trivalent oral poliovirus vaccine (tOPV). At 22 weeks of age, children received one challenge dose of tOPV, and children in arm D received one additional IPV dose...
November 6, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29105974/update-on-vaccine-derived-polioviruses-worldwide-january-2016%C3%A2-june-2017
#2
(no author information available yet)
No abstract text is available yet for this article.
November 3, 2017: Relevé épidémiologique Hebdomadaire
https://www.readbyqxmd.com/read/29100529/vaccine-related-poliovirus-shedding-in-trivalent-polio-vaccine-and-human-immunodeficiency-virus-status-analysis-from-under-five-children
#3
Joanne Hassan, Laura Wangai, Peter Borus, Christopher Khayeka-Wandabwa, Lucy Wanja Karani, Mercy Kithinji, Michael Kiptoo
BACKGROUND: Poliomyelitis is an acute viral infection caused by poliovirus and transmitted via the fecal-oral route. The causative agent is one of the three serotypes of poliovirus (serotypes 1, 2, 3) that differ slightly in capsid protein. Prolonged vaccine-related poliovirus shedding in human immunodeficiency virus (HIV) positive individuals has been linked to possible reservoir for reintroduction of polioviruses after eradication. The study therefore aimed at estimating the duration for vaccine-related poliovirus shedding among potentially and HIV-infected persons...
November 3, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/29095803/update-on-vaccine-derived-polioviruses-worldwide-january-2016-june-2017
#4
Jaume Jorba, Ousmane M Diop, Jane Iber, Elizabeth Henderson, Roland W Sutter, Steven G F Wassilak, Cara C Burns
In 1988, the World Health Assembly launched the Global Polio Eradication Initiative (GPEI) (1). Among the three wild poliovirus (WPV) serotypes, only type 1 (WPV1) has been detected since 2012. Since 2014, detection of WPV1 has been limited to three countries, with 37 cases in 2016 and 11 cases in 2017 as of September 27. The >99.99% decline worldwide in polio cases since the launch of the GPEI is attributable to the extensive use of the live, attenuated oral poliovirus vaccine (OPV) in mass vaccination campaigns and comprehensive national routine immunization programs...
November 3, 2017: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/28993765/prolonged-excretion-of-poliovirus-among-individuals-with-primary-immunodeficiency-disorder-an-analysis-of-the-world-health-organization-registry
#5
Grace Macklin, Yi Liao, Marina Takane, Kathleen Dooling, Stuart Gilmour, Ondrej Mach, Olen M Kew, Roland W Sutter
Individuals with primary immunodeficiency disorder may excrete poliovirus for extended periods and will constitute the only remaining reservoir of virus after eradication and withdrawal of oral poliovirus vaccine. Here, we analyzed the epidemiology of prolonged and chronic immunodeficiency-related vaccine-derived poliovirus cases in a registry maintained by the World Health Organization, to identify risk factors and determine the length of excretion. Between 1962 and 2016, there were 101 cases, with 94/101 (93%) prolonged excretors and 7/101 (7%) chronic excretors...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/28974220/the-risk-of-type-2-oral-polio-vaccine-use-in-post-cessation-outbreak-response
#6
Kevin A McCarthy, Guillaume Chabot-Couture, Michael Famulare, Hil M Lyons, Laina D Mercer
BACKGROUND: Wild type 2 poliovirus was last observed in 1999. The Sabin-strain oral polio vaccine type 2 (OPV2) was critical to eradication, but it is known to revert to a neurovirulent phenotype, causing vaccine-associated paralytic poliomyelitis. OPV2 is also transmissible and can establish circulating lineages, called circulating vaccine-derived polioviruses (cVDPVs), which can also cause paralytic outbreaks. Thus, in April 2016, OPV2 was removed from immunization activities worldwide...
October 4, 2017: BMC Medicine
https://www.readbyqxmd.com/read/28952612/patients-with-primary-immunodeficiencies-are-a-reservoir-of-poliovirus-and-a-risk-to-polio-eradication
#7
Asghar Aghamohammadi, Hassan Abolhassani, Necil Kutukculer, Steve G Wassilak, Mark A Pallansch, Samantha Kluglein, Jessica Quinn, Roland W Sutter, Xiaochuan Wang, Ozden Sanal, Tatiana Latysheva, Aydan Ikinciogullari, Ewa Bernatowska, Irina A Tuzankina, Beatriz T Costa-Carvalho, Jose Luis Franco, Raz Somech, Elif Karakoc-Aydiner, Surjit Singh, Liliana Bezrodnik, Francisco J Espinosa-Rosales, Anna Shcherbina, Yu-Lung Lau, Shigeaki Nonoyama, Fred Modell, Vicki Modell, Mohamed-Ridha Barbouche, Mark A McKinlay
Immunodeficiency-associated vaccine-derived polioviruses (iVDPVs) have been isolated from primary immunodeficiency (PID) patients exposed to oral poliovirus vaccine (OPV). Patients may excrete poliovirus strains for months or years; the excreted viruses are frequently highly divergent from the parental OPV and have been shown to be as neurovirulent as wild virus. Thus, these patients represent a potential reservoir for transmission of neurovirulent polioviruses in the post-eradication era. In support of WHO recommendations to better estimate the prevalence of poliovirus excreters among PIDs and characterize genetic evolution of these strains, 635 patients including 570 with primary antibody deficiencies and 65 combined immunodeficiencies were studied from 13 OPV-using countries...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/28949979/survey-of-poliovirus-antibodies-in-borno-and-yobe-states-north-eastern-nigeria
#8
Mustapha Modu Gofama, Harish Verma, Hamisu Abdullahi, Natalie A Molodecky, Kehinde T Craig, Utibe-Abasi Urua, Mohammed Ashir Garba, Mohammed Arab Alhaji, William C Weldon, M Steven Oberste, Fiona Braka, Ado J G Muhammad, Roland W Sutter
BACKGROUND: Nigeria remains one of only three polio-endemic countries in the world. In 2016, after an absence of 2 years, wild poliovirus serotype 1 was again detected in North-Eastern Nigeria. To better guide programmatic action, we assessed the immunity status of infants and children in Borno and Yobe states, and evaluated the impact of recently introduced inactivated poliovirus vaccine (IPV) on antibody seroprevalence. METHODS AND FINDINGS: We conducted a facility-based study of seroprevalence to poliovirus serotypes 1, 2 and 3 among health-seeking patients in two sites each of Borno and Yobe States...
2017: PloS One
https://www.readbyqxmd.com/read/28930011/poliovirus-excretion-in-children-with-primary-immunodeficiency-disorders-india
#9
Madhu Chhanda Mohanty, Manisha Rajan Madkaikar, Mukesh Desai, Prasad Taur, Uma Prajwal Nalavade, Deepa Kailash Sharma, Maya Gupta, Aparna Dalvi, Snehal Shabrish, Manasi Kulkarni, Jahnavi Aluri, Jagadish Mohanrao Deshpande
Prolonged excretion of poliovirus can occur in immunodeficient patients who receive oral polio vaccine, which may lead to propagation of highly divergent vaccine-derived polioviruses (VDPVs), posing a concern for global polio eradication. This study aimed to estimate the proportion of primary immunodeficient children with enterovirus infection and to identify the long-term polio/nonpolio enterovirus excreters in a tertiary care unit in Mumbai, India. During September 2014-April 2017, 151 patients received diagnoses of primary immunodeficiency (PID)...
October 2017: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/28890193/evaluating-cessation-of-the-type-2-oral-polio-vaccine-by-modeling-pre-and-post-cessation-detection-rates
#10
Steve J Kroiss, Michael Famulare, Hil Lyons, Kevin A McCarthy, Laina D Mercer, Guillaume Chabot-Couture
The globally synchronized removal of the attenuated Sabin type 2 strain from the oral polio vaccine (OPV) in April 2016 marked a major change in polio vaccination policy. This change will provide a significant reduction in the burden of vaccine-associated paralytic polio (VAPP), but may increase the risk of circulating vaccine-derived poliovirus (cVDPV2) outbreaks during the transition period. This risk can be monitored by tracking the disappearance of Sabin-like type 2 (SL2) using data from the polio surveillance system...
September 7, 2017: Vaccine
https://www.readbyqxmd.com/read/28882442/polio-immunity-and-the-impact-of-mass-immunization-campaigns-in-the-democratic-republic-of-the-congo
#11
Arend Voorman, Nicole A Hoff, Reena H Doshi, Vivian Alfonso, Patrick Mukadi, Jean-Jacques Muyembe-Tamfum, Emile Okitolonda Wemakoy, Ado Bwaka, William Weldon, Sue Gerber, Anne W Rimoin
BACKGROUND: In order to prevent outbreaks from wild and vaccine-derived poliovirus, maintenance of population immunity in non-endemic countries is critical. METHODS: We estimated population seroprevalence using dried blood spots collected from 4893 children 6-59months olds in the 2013-2014 Demographic and Health Survey in the Democratic Republic of the Congo (DRC). RESULTS: Population immunity was 81%, 90%, and 70% for poliovirus types 1, 2, and 3, respectively...
October 9, 2017: Vaccine
https://www.readbyqxmd.com/read/28838198/lessons-from-globally-coordinated-cessation-of-serotype-2-oral-poliovirus-vaccine-for-the-remaining-serotypes
#12
Kimberly M Thompson, Radboud J Duintjer Tebbens
Background: Comparing model expectations with the experience of oral poliovirus vaccine (OPV) containing serotype 2 (OPV2) cessation can inform risk management for the expected cessation of OPV containing serotypes 1 and 3 (OPV13). Methods: We compare the expected post-OPV2-cessation OPV2-related viruses from models with the evidence available approximately 6 months after OPV2 cessation. We also model the trade-offs of use vs nonuse of monovalent OPV (mOPV) for outbreak response considering all 3 serotypes...
July 1, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28838194/lessons-from-the-polio-endgame-overcoming-the-failure-to-vaccinate-and-the-role-of-subpopulations-in-maintaining-transmission
#13
Kimberly M Thompson, Radboud J Duintjer Tebbens
Background: Recent detections of circulating serotype 2 vaccine-derived poliovirus in northern Nigeria (Borno and Sokoto states) and Pakistan (Balochistan Province) and serotype 1 wild poliovirus in Pakistan, Afghanistan, and Nigeria (Borno) represent public health emergencies that require aggressive response. Methods: We demonstrate the importance of undervaccinated subpopulations, using an existing dynamic poliovirus transmission and oral poliovirus vaccine evolution model...
July 1, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28838193/considerations-for-the-full-global-withdrawal-of-oral-polio-vaccine-after-eradication-of-polio
#14
Lee M Hampton, Gaël Maufras du Châtellier, Jacqueline Fournier-Caruana, Ann Ottosen, Jennifer Rubin, Lisa Menning, Margaret Farrell, Stephanie Shendale, Manish Patel
Eliminating the risk of polio from vaccine-derived polioviruses is essential for creating a polio-free world, and eliminating that risk will require stopping use of all oral polio vaccines (OPVs) once all types of wild polioviruses have been eradicated. In many ways, the experience with the global switch from trivalent OPV (tOPV) to bivalent OPV (bOPV) can inform the eventual full global withdrawal of OPV. Significant preparation will be needed for a thorough, synchronized, and full withdrawal of OPV, and such preparation would be aided by setting a reasonably firm date for OPV withdrawal as far in advance as possible, ideally at least 24 months...
July 1, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28838178/introduction-of-inactivated-poliovirus-vaccine-and-trivalent-oral-polio-vaccine-bivalent-oral-polio-vaccine-switch-in-the-african-region
#15
Carol Tevi-Benissan, Joseph Okeibunor, Gaël Maufras du Châtellier, Afework Assefa, Joseph Nsiari-Muzenyi Biey, Dah Cheikh, Messeret Eshetu, Blanche-Philomene Anya, Halima Dao, Yusuf Nasir, Bartholomew Dicky Akanmori, Richard Mihigo
The Polio Eradication and Endgame Strategic plan outlines the phased removal of oral polio vaccines (OPVs), starting with type 2 poliovirus-containing vaccine and introduction of inactivated polio vaccine in routine immunization to mitigate against risk of vaccine-associated paralytic polio and circulating vaccine-derived poliovirus. The objective includes strengthening routine immunization as the primary pillar to sustaining high population immunity. After 2 years without reporting any wild poliovirus (July 2014-2016), the region undertook the synchronized switch from trivalent OPV (tOPV) to bivalent OPV (bOPV) as recommended by the Strategic Advisory Group of Experts on Immunization...
July 1, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28838170/experience-with-inactivated-polio-vaccine-introduction-and-the-switch-from-trivalent-to-bivalent-oral-polio-vaccine-in-the-world-health-organization-s-western-pacific-region
#16
Santosh Gurung, Jennifer B Harris, Abu Obeida Eltayeb, Lee M Hampton, Sergey Diorditsa, Tigran Avagyan, W William Schluter
The World Health Organization (WHO) Western Pacific Region (WPR) has maintained its polio-free status since 2000. The emergence of vaccine-derived polioviruses (VDPVs), however, remains a risk, as oral polio vaccine (OPV) is still used in many of the region's countries, and pockets of unimmunized or underimmunized children exist in some countries. From 2014 to 2016, the region participated in the globally coordinated efforts to introduce inactivated polio vaccine (IPV) into all countries that did not yet include it in their national immunization schedules, and to "switch" from trivalent OPV (tOPV) to bivalent OPV (bOPV) in all countries still using OPV in 2016...
July 1, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28838168/disposing-of-excess-vaccines-after-the-withdrawal-of-oral-polio-vaccine
#17
Sarah Wanyoike, Alejandro Ramirez Gonzalez, Samantha B Dolan, Julie Garon, Chantal Laroche Veira, Lee M Hampton, Diana Chang Blanc, Manish M Patel
Until recently, waste management for national immunization programs was limited to sharps waste, empty vaccine vials, or vaccines that had expired or were no longer usable. However, because wild-type 2 poliovirus has been eradicated, the World Health Organization's (WHO's) Strategic Advisory Group of Experts on Immunization deemed that all countries must simultaneously cease use of the type 2 oral polio vaccine and recommended that all countries and territories using oral polio vaccine (OPV) "switch" from trivalent OPV (tOPV; types 1, 2, and 3 polioviruses) to bivalent OPV (bOPV; types 1 and 3 polioviruses) during a 2-week period in April 2016...
July 1, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28838162/monitoring-and-validation-of-the-global-replacement-of-topv-with-bopv-april-may-2016
#18
Margaret Farrell, Lee M Hampton, Stephanie Shendale, Lisa Menning, Alejandro Ramirez Gonzalez, Julie Garon, Samantha B Dolan, Gaël Maufras du Châtellier, Sarah Wanyoike, Diana Chang Blanc, Manish M Patel
The phased withdrawal of oral polio vaccine (OPV) associated with the Polio Eradication and Endgame Strategic Plan 2013-2018 began with the synchronized global replacement of trivalent OPV (tOPV) with bivalent OPV (bOPV) during April - May 2016, a transition referred to as the "switch." The World Health Organization's (WHO) Strategic Advisory Group of Experts (SAGE) on Immunization recommended conducting this synchronized switch in all 155 OPV-using countries and territories (which collectively administered several hundred million doses of tOPV each year via several hundred thousand facilities) to reduce risks of re-emergence of vaccine-derived polioviruses...
July 1, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28838159/a-supply-and-demand-management-perspective-on-the-accelerated-global-introductions-of-inactivated-poliovirus-vaccine-in-a-constrained-supply-market
#19
Ian Lewis, Ann Ottosen, Jennifer Rubin, Diana Chang Blanc, Simona Zipursky, Emily Wootton
A total of 105 countries have introduced IPV as of September 2016 of which 85 have procured the vaccine through UNICEF. The Global Eradication and Endgame Strategic Plan 2013-2018 called for the rapid introduction of at least one dose of IPV into routine immunization schedules in 126 all OPV-using countries by the end of 2015. At the time of initiating the procurement process, demand was estimated based on global modeling rather than individual country indications. In its capacity as procurement agency for the Global Polio Eradication Initiative and Gavi, the Vaccine Alliance, UNICEF set out to secure access to IPV supply for around 100 countries...
July 1, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28806355/seroprevalence-of-anti-polio-antibodies-in-children-from-polio-high-risk-areas-of-pakistan-a-cross-sectional-survey-2015-2016
#20
Imtiaz Hussain, Ondrej Mach, Atif Habib, Zaid Bhatti, Zamir Suhag, M Steven Oberste, William C Weldon, Roland W Sutter, Sajid B Soofi, Zulfiqar A Bhutta
BACKGROUND: Pakistan is one of the 3 remaining wild poliovirus endemic countries. We collected sera from children to assess the prevalence of poliovirus antibodies in selected high-risk areas for poliovirus transmission. METHODS: Children in 2 age groups (6-11 and 36-48 months) were randomly selected between November 2015 and March 2016 in 6 areas of Pakistan (Sindh Province: Karachi and Kashmore; Khyber Pakhtunkhwa Province: Peshawar, Bannu and Nowshera; Punjab Province: Faisalabad)...
September 2017: Pediatric Infectious Disease Journal
keyword
keyword
4793
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"