keyword
MENU ▼
Read by QxMD icon Read
search

Vaccine derived poliovirus

keyword
https://www.readbyqxmd.com/read/28542124/virologic-monitoring-of-poliovirus-type-2-after-oral-poliovirus-vaccine-type-2-withdrawal-in-april-2016-worldwide-2016-2017
#1
Ousmane M Diop, Humayun Asghar, Evgeniy Gavrilin, Nicksy Gumede Moeletsi, Gloria Rey Benito, Fem Paladin, Sirima Pattamadilok, Yan Zhang, Ajay Goel, Arshad Quddus
The Global Polio Eradication Initiative (GPEI) has made substantial progress since its launch in 1988; only 37 wild poliovirus type 1 (WPV1) cases were detected in 2016, the lowest annual count ever. Wild poliovirus type 3 has not been detected since November 2012, and wild poliovirus type 2 was officially declared eradicated in September 2015. This success is attributable to the wide use of live oral poliovirus vaccines (OPVs). Since 2001, numerous outbreaks were caused by the emergence of genetically divergent vaccine-derived polioviruses (VDPVs) whose genetic drift from the parental OPV strains indicates prolonged replication or circulation (1)...
May 26, 2017: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/28528761/responding-to-a-cvdpv1-outbreak-in-ukraine-implications-challenges-and-opportunities
#2
Nino Khetsuriani, Ihor Perehinets, Dorit Nitzan, Dragoslav Popovic, Thomas Moran, Vusala Allahverdiyeva, Shahin Huseynov, Eugene Gavrilin, Liudmyla Slobodianyk, Olha Izhyk, Anna Sukhodolska, Sahar Hegazi, Katerina Bulavinova, Sergei Platov, Patrick O'Connor
BACKGROUND: The European Region, certified polio-free in 2002, remains at risk of wild poliovirus reintroduction and emergence of circulating vaccine-derived polioviruses (cVDPV) until global polio eradication is achieved, as demonstrated by the cVDPV1 outbreak in Ukraine in 2015. METHODS: We reviewed epidemiologic, clinical and virology data on cVDPV cases, surveillance and immunization coverage data, and reports of outbreak-related surveys, country missions, and expert group meetings...
May 18, 2017: Vaccine
https://www.readbyqxmd.com/read/28480271/epidemiological-surveillance-of-poliomyelitis-during-the-military-and-political-conflict-in-the-central-african-republic-2013-and-2014
#3
Alain Farra, Ella C Gonofio, Alexandre Manirakiza, Arthur Mazitchi, Raphaël Mbaïlao, Casimir Manengu, Ionela Gouandjika-Vasilache
BACKGROUND: Since December 2012, the Central African Republic (CAR) has been undergoing a severe military and political conflict. This situation has resulted in general insecurity and total disorganization of surveillance activities, including those for acute flaccid paralysis (AFP). In this study, we used laboratory data to evaluate surveillance of AFP in 2013 and 2014, the most critical period of the conflict. METHODS: The laboratory data on AFP were analyzed retrospectively for the age, sex, vaccination status (oral poliovirus vaccines), and geographical origin of the samples...
2017: Open Forum Infectious Diseases
https://www.readbyqxmd.com/read/28468861/detection-of-emerging-vaccine-related-polioviruses-by-deep-sequencing
#4
Malaya K Sahoo, Marisa Holubar, ChunHong Huang, Alisha Mohamed-Hadley, Yuanyuan Liu, Jesse J Waggoner, Stephanie B Troy, Lourdes Garcia-Garcia, Leticia Ferreyra-Reyes, Yvonne Maldonado, Benjamin A Pinsky
Oral poliovirus vaccine (OPV) can mutate to regain neurovirulence. To date, evaluation of these mutations has primarily been performed on culture-enriched isolates using conventional Sanger sequencing. We therefore developed a culture-independent, deep sequencing method targeting the 5' untranslated region (UTR) and P1 genomic region to characterize vaccine-related poliovirus variants. Error analysis of the deep sequencing method demonstrated reliable detection of poliovirus mutations at levels <1%, depending on read depth...
May 3, 2017: Journal of Clinical Microbiology
https://www.readbyqxmd.com/read/28419204/immune-serum-from-sabin-inactivated-poliovirus-vaccine-immunization-neutralizes-multiple-individual-wild-and-vaccine-derived-polioviruses
#5
Mingbo Sun, Changgui Li, Wenbo Xu, Guoyang Liao, Rongcheng Li, Jian Zhou, Yanping Li, Wei Cai, Dongmei Yan, Yanchun Che, Zhifang Ying, Jianfeng Wang, Huijuan Yang, Yan Ma, Lei Ma, Guang Ji, Li Shi, Shude Jiang, Qihan Li
Background: A Sabin strain-based inactivated poliomyelitis vaccine (Sabin-IPV) is the rational option for completely eradicating poliovirus transmission. The neutralizing capacity of Sabin-IPV immune serum to different strains of poliovirus is a key indicator of the clinical protective efficacy of this vaccine. Methods: Sera collected from 500 infants enrolled in a randomized, blinded, positive control, phase 2 clinical trial were randomly divided into 5 groups: Groups A, B, and C received high, medium, and low doses, respectively, of Sabin-IPV, while groups D and E received trivalent oral polio vaccine and Salk strain-based IPV, respectively, all on the same schedule...
May 15, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28390186/acute-flaccid-paralysis-surveillance-in-bosnia-and-herzegovina-recent-isolation-of-two-sabin-like-type-2-poliovirus
#6
Stefano Fontana, Gabriele Buttinelli, Stefano Fiore, Mirsada Mulaomerovic, Jela Aćimović, Concetta Amato, Roberto Delogu, Giovanni Rezza, Paola Stefanelli
The WHO Regional Commission for the Certification of Poliomyelitis Eradication has recently indicated Bosnia and Herzegovina (B&H) as a high risk country for transmission, following importation, of wild poliovirus (WPV) or circulating vaccine-derived poliovirus (cVDPV). We analyzed data on Acute Flaccid Paralysis (AFP) surveillance between 2007 to 2016, and the trend of polio immunization coverage in B&H. The majority of AFP cases was recorded in 2016 suggesting an enhancement of the AFP surveillance activities...
April 8, 2017: Journal of Medical Virology
https://www.readbyqxmd.com/read/28384129/surveillance-systems-to-track-progress-toward-polio-eradication-worldwide-2015-2016
#7
Edmond F Maes, Ousmane M Diop, Jaume Jorba, Smita Chavan, Rudolph H Tangermann, Steven G F Wassilak
Global measures to eradicate polio began in 1988; as of 2014, four of six World Health Organization (WHO) regions have been certified polio-free. Within the two endemic regions (African and Eastern Mediterranean), Nigeria, Afghanistan, and Pakistan have never interrupted transmission of wild poliovirus (WPV) (1). The primary means of detecting poliovirus transmission is surveillance for acute flaccid paralysis (AFP) among children aged <15 years, combined with collection and testing of stool specimens from persons with AFP for detection of WPV and vaccine-derived polioviruses (VDPVs) (viruses that differ genetically from vaccine viruses and can emerge in areas with low vaccination coverage and cause paralysis) in WHO-accredited laboratories within the Global Polio Laboratory Network (2,3)...
April 7, 2017: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/28362135/immunogenicity-and-safety-evaluation-of-bivalent-types-1-and-3-oral-poliovirus-vaccine-by-comparing-different-poliomyelitis-vaccination-schedules-in-china-a-randomized-controlled-non-inferiority-clinical-trial
#8
Jingjun Qiu, Yunkai Yang, Lirong Huang, Ling Wang, Zhiwei Jiang, Jian Gong, Wei Wang, Hongyan Wang, Shaohong Guo, Chanjuan Li, Shuyuan Wei, Zhaojun Mo, Jielai Xia
BACKGROUND: The type 2 component of the oral poliovirus vaccine is targeted for global withdrawal through a switch from the trivalent oral poliovirus vaccine (tOPV) to a bivalent oral poliovirus vaccine (bOPV). The switch is intended to prevent paralytic polio caused by circulating vaccine-derived poliovirus type 2. We aimed to assess the immunogenicity and safety profile of 6 vaccination schedules with different sequential doses of inactivated poliovirus vaccine (IPV), tOPV, or bOPV...
June 3, 2017: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/28361789/vaccine-associated-paralytic-poliomyelitis-unmasking-common-variable-immunodeficiency
#9
Sunil Gomber, Vanny Arora, Pooja Dewan
BACKGROUND: Oral polio vaccine can rarely lead to Vaccine-associated paralytic poliomyelitis (VAPP). CASE CHARACTERISTICS: A 2-year-old child with asymmetric paralysis of lower limbs following first booster of oral polio vaccine; type 2 Vaccine-derived poliovirus (VDPV) isolated. Subsequently, the child was diagnosed to have common variable immunodeficiency. OUTCOME: Paralysis gradually improved on follow-up; monthly intravenous immunoglobulin therapy started for primary immunodeficiency...
March 15, 2017: Indian Pediatrics
https://www.readbyqxmd.com/read/28343771/characterization-of-human-monoclonal-antibodies-that-neutralize-multiple-poliovirus-serotypes
#10
Rama Devudu Puligedda, Diana Kouiavskaia, Fetweh H Al-Saleem, Chandana Devi Kattala, Usman Nabi, Hamid Yaqoob, V Sandeep Bhagavathula, Rashmi Sharma, Konstantin Chumakov, Scott K Dessain
Following the eradication of wild poliovirus (PV), achieving and maintaining a polio-free status will require eliminating potentially pathogenic PV strains derived from the oral attenuated vaccine. For this purpose, a combination of non-cross-resistant drugs, such as small molecules and neutralizing monoclonal antibodies (mAbs), may be ideal. We previously isolated chimpanzee and human mAbs capable of neutralizing multiple PV types (cross-neutralization). Here, we describe three additional human mAbs that neutralize types 1 and 2 PV and one mAb that neutralizes all three types...
March 23, 2017: Vaccine
https://www.readbyqxmd.com/read/28340348/the-evolutionary-pathway-to-virulence-of-an-rna-virus
#11
COMMENT
Adi Stern, Ming Te Yeh, Tal Zinger, Matt Smith, Caroline Wright, Guy Ling, Rasmus Nielsen, Andrew Macadam, Raul Andino
Paralytic polio once afflicted almost half a million children each year. The attenuated oral polio vaccine (OPV) has enabled world-wide vaccination efforts, which resulted in nearly complete control of the disease. However, poliovirus eradication is hampered globally by epidemics of vaccine-derived polio. Here, we describe a combined theoretical and experimental strategy that describes the molecular events leading from OPV to virulent strains. We discover that similar evolutionary events occur in most epidemics...
March 23, 2017: Cell
https://www.readbyqxmd.com/read/28340335/experimental-evolution-to-study-virus-emergence
#12
COMMENT
Nathan D Grubaugh, Kristian G Andersen
Understanding how viruses adapt to new environments and acquire new phenotypes is critical for developing comprehensive responses to outbreaks. By studying the emergence of vaccine-derived poliovirus outbreaks, Stern et al. describe how a combination of sequence analysis and experimental evolution can be used to reveal adaptive pathways.
March 23, 2017: Cell
https://www.readbyqxmd.com/read/28194449/comparison-of-ipv-to-topv-week-39-boost-of-primary-opv-vaccination-in-indian-infants-an-open-labelled-randomized-controlled-trial
#13
Suman Kanungo, Deok Ryun Kim, Bisakha Haldar, Cynthia Snider, Uma Nalavade, Soon Ae Kim, Ju Yeon Park, Anuradha Sinha, Aiyel Haque Mallick, Byomkesh Manna, Dipika Sur, Ranjan Kumar Nandy, Jagadish M Deshpande, Cecil Czerkinsky, Thomas F Wierzba, William A Petri, Mohammad Ali, Ayan Dey
BACKGROUND: The final endgame strategy of global polio eradication initiative includes switching from trivalent oral poliovirus vaccines (tOPV) to bivalent oral polio vaccine (bOPV), and introduction of inactivated poliovirus vaccine (IPV). This study compares IPV with tOPV week 39 boost in Indian infants. METHODS: Starting 28 March 2012, we enrolled 372 Indian infant-mother pairs from Kolkata, India in an open-label, block-randomized, controlled trial comparing a 39 week tOPV to an IPV boost among infants immunized with three doses of tOPV...
January 2017: Heliyon
https://www.readbyqxmd.com/read/28140752/concomitant-administration-of-diphtheria-tetanus-acellular-pertussis-and-inactivated-poliovirus-vaccine-derived-from-sabin-strains-dtap-sipv-with-pentavalent-rotavirus-vaccine-in-japanese-infants
#14
Yoshiyuki Tanaka, Ruriko Yokokawa, Han Shi Rong, Hiroyuki Kishino, Jon E Stek, Margaret Nelson, Jody Lawrence
Rotavirus is the leading cause of severe acute gastroenteritis in infants and young children. Most children are infected with rotavirus, and the health and economic burdens of rotavirus gastroenteritis on healthcare systems and families are considerable. In 2012 pentavalent rotavirus vaccine (RV5) and diphtheria, tetanus, acellular pertussis and inactivated poliovirus vaccine derived from Sabin strains (DTaP-sIPV) were licensed in Japan. We examined the immunogenicity and safety of DTaP-sIPV when administrated concomitantly with RV5 in Japanese infants...
June 3, 2017: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/28081056/guidance-for-assessment-of-poliovirus-vaccination-status-and-vaccination-of-children-who-have-received-poliovirus-vaccine-outside-the-united-states
#15
Mona Marin, Manisha Patel, Steve Oberste, Mark A Pallansch
In 1988, the World Health Assembly resolved to eradicate poliomyelitis (polio). Since then, wild poliovirus (WPV) cases have declined by >99.9%, from an estimated 350,000 cases of polio each year to 74 cases in two countries in 2015 (1). This decrease was achieved primarily through the use of trivalent oral poliovirus vaccine (tOPV), which contains types 1, 2, and 3 live, attenuated polioviruses. Since 2000, the United States has exclusively used inactivated polio vaccine (IPV), which contains all three poliovirus types (2,3)...
January 13, 2017: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/28057103/-inactivated-poliovirus-vaccines-an-inevitable-choice-for-eliminating-poliomyelitis
#16
J D Vidor, Shu Jean-Denis
The inactivated poliovirus vaccine (IPV) is a very old tool in the fight against poliomyelitis. Though supplanted by oral poliovirus vaccine (OPV) in the 1960s and 1970s, the IPV has now become an inevitable choice because of the increasingly recognized risks associated with continuous use of OPVs. Following the pioneering work of Jonas Salk, who established key principles for the IPV, considerable experience has accumulated over the years. This work has led to modern Salk IPV-containing vaccines, based on the use of inactivated wildtype polioviruses, which have been deployed for routine use in many countries...
December 6, 2016: Zhonghua Yu Fang Yi Xue za Zhi [Chinese Journal of Preventive Medicine]
https://www.readbyqxmd.com/read/28050469/interference-of-vaccine-derived-polio-viruses-with-diagnosis-of-enteroviral-diseases-in-neonatal-period
#17
Mohammad Saeed Sasan, Alireza Ataei Nakhaei, Abdolvahab Alborzi, Mazyar Ziyaeyan
INTRODUCTION: Enteroviruses (EV) are a common cause of neonatal sepsis especially at the junction of summer and fall. AIM: This study was planned to find the frequency of Enteroviral (EV) sepsis among neonates with clinical sepsis. MATERIALS AND METHODS: This is a prospective descriptive study. Rectal and pharyngeal swab samples were taken from all neonates with clinical sepsis and a control group of neonates with simple jaundice. EV was confirmed by both cell culture and RT-PCR...
November 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28046048/transformation-and-tumorigenicity-testing-of-simian-cell-lines-and-evaluation-of-poliovirus-replication
#18
Silvia Dotti, Tina Lombardo, Riccardo Villa, Andrea Cacciamali, Cinzia Zanotti, Nadia Andrea Andreani, Stefano Cinotti, Maura Ferrari
The key role of cell cultures in different scientific fields is worldwide recognized, both as in vitro research models alternative to laboratory animals and substrates for biological production. However, many safety concerns rise from the use of animal/human cell lines that may be tumorigenic, leading to potential adverse contaminations in cell-derived biologicals. In order to evaluate the suitability of 13 different cell lines for Poliovirus vaccine production, safety and quality, in vitro/in vivo tumorigenicity and Poliovirus propagation properties were evaluated...
2017: PloS One
https://www.readbyqxmd.com/read/28039136/laboratory-surveillance-of-polio-and-other-enteroviruses-in-high-risk-populations-and-environmental-samples
#19
Vasiliki Pogka, Stavroula Labropoulou, Mary Emmanouil, Androniki Voulgari-Kokota, Alexandra Vernardaki, Theano Georgakopoulou, Andreas F Mentis
In the context of poliomyelitis eradication, a reinforced supplementary laboratory surveillance of enteroviruses was implemented in Greece. Between 2008 and 2014, the Hellenic Polioviruses/Enteroviruses Reference Laboratory performed detailed supplementary surveillance of circulating enteroviruses among healthy individuals in high-risk population groups, among immigrants from countries in which poliovirus is endemic, and in environmental samples. In total, 722 stool samples and 179 sewage water samples were included in the study...
March 1, 2017: Applied and Environmental Microbiology
https://www.readbyqxmd.com/read/28034372/public-health-response-to-the-silent-reintroduction-of-wild-poliovirus-to-israel-2013-2014
#20
REVIEW
J Moran-Gilad, E Kaliner, M Gdalevich, I Grotto
During 2013/14, Israel witnessed the silent reintroduction and sustained transmission of wild poliovirus type 1 (WPV1) detected through routine environmental surveillance performed on sewage samples. The public health response to silent poliovirus transmission in a population with high inactivated polio vaccine (IPV) coverage poses an emerging challenge towards the 'End Game' of global poliovirus eradication. This paper reviews the risk assessment, risk management and risk communication aspects of this poliovirus incident...
December 1, 2016: Clinical Microbiology and Infection
keyword
keyword
4793
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"