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Traumatic brain injury concussion

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https://www.readbyqxmd.com/read/29766124/routine-repeat-head-ct-may-not-be-necessary-for-patients-with-mild-tbi
#1
Claire B Rosen, Diego D Luy, Molly R Deane, Thomas M Scalea, Deborah M Stein
Background: Routine repeat cranial CT (RHCT) is standard of care for CT-verified traumatic brain injury (TBI). Despite mixed evidence, those with mild TBI are subject to radiation and expense from serial CT scans. Thus, we investigated the necessity and utility of RHCT for patients with mild TBI. We hypothesized that repeat head CT in these patients would not alter patient care or outcomes. Methods: We retrospectively studied patients suffering from mild TBI (Glasgow Coma Scale (GCS) score 13-15) and treated at the R Adams Cowley Shock Trauma Center from November 2014 through January 2015...
2018: Trauma surgery & acute care open
https://www.readbyqxmd.com/read/29757458/posttraumatic-headache-basic-mechanisms-and-therapeutic-targets
#2
REVIEW
Joshua Kamins, Andrew Charles
Frequent or continuous headache, often refractory to medical therapy, is a common occurrence after head trauma. In addition to being the most common acute symptom after traumatic brain injury (TBI), headache is also one of the most persistent and disabling symptoms. Different studies indicate that 18-58% of those suffering a TBI will have significant headache at 1 year following the trauma. In addition to being disabling on its own, posttraumatic headache (PTH) is a predictor of overall outcome after concussion...
May 14, 2018: Headache
https://www.readbyqxmd.com/read/29757076/economic-evaluation-of-concussion-programs-in-the-state-of-idaho-the-collective-potential-of-prevention-and-clinical-care
#3
Susie Bergeron, Hilary Flint, Zeynep Hansen
Concussion, or mild traumatic brain injury, especially among young children, teenagers, and young adults, is a significant problem in Ada County, Idaho, and the United States. Although much has been learned about concussion, considerable controversy and gaps in knowledge still exist in many areas of research, leading to variation in concussion assessment, treatment, and management protocols. Health systems can positively impact concussion outcomes through community education and outreach, and provision of timely, coordinated, evidence-based clinical care...
May 14, 2018: Population Health Management
https://www.readbyqxmd.com/read/29755402/default-mode-network-oscillatory-coupling-is-increased-following-concussion
#4
Benjamin T Dunkley, Karolina Urban, Leodante Da Costa, Simeon M Wong, Elizabeth W Pang, Margot J Taylor
Concussion is a common form of mild traumatic brain injury. Despite the descriptor "mild," a single injury can leave long-lasting and sustained alterations to brain function, including changes to localized activity and large-scale interregional communication. Cognitive complaints are thought to arise from such functional deficits. We investigated the impact of injury on neurophysiological and functionally specialized resting networks, known as intrinsic connectivity networks (ICNs), using magnetoencephalography...
2018: Frontiers in Neurology
https://www.readbyqxmd.com/read/29742529/heterotopic-ossification-formation-following-a-simple-concussion-a-case-report
#5
Patrick K O'Callaghan, Elliott Carter, Zeke Walton, Russell Chapin, Evelyn Bruner
CASE: A 19-year-old woman presented with a 3-month history of an enlarging lesion on the proximal aspect of the femur. After imaging studies and a biopsy had been performed, the mass was determined to represent heterotopic ossification (HO). The only known risk factor was a history of concussion. The mass was resected and, as of the 12-month follow-up, had not recurred. CONCLUSION: HO is a potentially serious complication of ossification in soft tissues that can develop secondary to several disease states; it commonly occurs following traumatic brain injury...
May 9, 2018: JBJS Case Connector
https://www.readbyqxmd.com/read/29738554/repeated-mild-traumatic-brain-injury-can-cause-acute-neurologic-impairment-without-overt-structural-damage-in-juvenile-rats
#6
Alicia Meconi, Ryan C Wortman, David K Wright, Katie J Neale, Melissa Clarkson, Sandy R Shultz, Brian R Christie
Repeated concussion is becoming increasingly recognized as a serious public health concern around the world. Moreover, there is a greater awareness amongst health professionals of the potential for repeated pediatric concussions to detrimentally alter the structure and function of the developing brain. To better study this issue, we developed an awake closed head injury (ACHI) model that enabled repeated concussions to be performed reliably and reproducibly in juvenile rats. A neurological assessment protocol (NAP) score was generated immediately after each ACHI to help quantify the cumulative effects of repeated injury on level of consciousness, and basic motor and reflexive capacity...
2018: PloS One
https://www.readbyqxmd.com/read/29734566/hyperbaric-oxygen-for-post-concussive-symptoms-in-united-states-military-service-members-a-randomized-clinical-trial
#7
Lindell K Weaver, Steffanie H Wilson, Anne S Lindblad, Susan Churchill, Kayla Deru, Robert C Price, Chris S Williams, William W Orrison, James M Walker, Anna Meehan, Susan Mirow
Background: In prior military randomized trials, participants with persistent symptoms after mild traumatic brain injury (TBI) reported improvement regardless of receiving hyperbaric oxygen (HBO₂) or sham intervention. This study's objectives were to identify outcomes for future efficacy trials and describe changes by intervention. Methods: This Phase II, randomized, double-blind, sham-controlled trial enrolled military personnel with mild TBI and persistent post-concussive symptoms...
March 2018: Undersea & Hyperbaric Medicine: Journal of the Undersea and Hyperbaric Medical Society, Inc
https://www.readbyqxmd.com/read/29726314/effect-of-depression-on-cognition-after-mild-traumatic-brain-injury-in-adults
#8
Douglas P Terry, Michelle Brassil, Grant L Iverson, William J Panenka, Noah D Silverberg
OBJECTIVE: The current study examined the effect of depression on cognitive test performance in a sample of adults seeking treatment for a mild traumatic brain injury (MTBI). We hypothesized that patients with greater depressive symptoms would perform worse on tasks of fluid cognition compared to those without depression, after controlling for potential confounds. METHOD: Patients (N = 76) completed a brief cognitive test battery (NIH Toolbox Cognition Battery; NIHTB-CB) and a depression screening questionnaire (PHQ-9) at 11...
May 4, 2018: Clinical Neuropsychologist
https://www.readbyqxmd.com/read/29712487/prospective-study-of-myelin-water-fraction-changes-after-mild-traumatic-brain-injury-in-collegiate-contact-sports
#9
Heather S Spader, Douglas C Dean, W Curt LaFrance, Neha P Raukar, G Rees Cosgrove, Stephanie A Eyerly-Webb, Anna Ellermeier, Stephen Correia, Sean C L Deoni, Jeffrey Rogg
OBJECTIVE Mild traumatic brain injury (mTBI) in athletes, including concussion, is increasingly being found to have long-term sequelae. Current imaging techniques have not been able to identify early damage caused by mTBI that is predictive of long-term symptoms or chronic traumatic encephalopathy. In this preliminary feasibility study, the authors investigated the use of an emerging magnetic resonance imaging (MRI) technique, multicomponent driven equilibrium single pulse observation of T1 and T2 (mcDESPOT), in visualizing acute and chronic white matter changes after mTBI in collegiate football and rugby players...
May 1, 2018: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29705573/the-long-term-outcomes-of-sport-related-concussion-in-pediatric-populations
#10
R Davis Moore, Jacob J Kay, Dave Ellemberg
Although the field of concussion research is rapidly growing, the majority of research has focused on injured adults, with children being an often-neglected population (Kirkwood et al., 2006). Traumatic brain injury is a leading cause of death and disability in children (Langlois et al., 2003), with over 1.5 million cases being treated in North America annually (Yeates et al., 1999). Approximately 75% of these injuries are classified as a concussion (Faul et al., 2010). Further, children are disproportionately affected by sports-related injuries, with 65% of all pediatric concussions occurring during sport and recreation (CDC, 2007)...
April 26, 2018: International Journal of Psychophysiology
https://www.readbyqxmd.com/read/29701560/high-prevalence-of-prior-contact-sports-play-and-concussion-among-orthopedic-and-neurosurgical-department-chairs
#11
Je Yeong Sone, S Courtney-Kay Lamb, Kristina Techar, Vikalpa Dammavalam, Mohit Uppal, Cedric Williams, Thomas Bergman, David Tupper, Paul Ort, Uzma Samadani
OBJECTIVE Increased understanding of the consequences of traumatic brain injury has heightened concerns about youth participation in contact sports. This study investigated the prevalence of high school and collegiate contact sports play and concussion history among surgical department chairs. METHODS A cross-sectional survey was administered to 107 orthopedic and 74 neurosurgery chairs. Responses were compared to published historical population norms for contact sports (high school 27.74%, collegiate 1.44%), football (high school 10...
April 27, 2018: Journal of Neurosurgery. Pediatrics
https://www.readbyqxmd.com/read/29690799/prediction-of-persistent-post-concussion-symptoms-following-mild-traumatic-brain-injury
#12
Maryse C Cnossen, Joukje van der Naalt, Jacoba M Spikman, Daan Nieboer, John K Yue, Ethan A Winkler, Geoffrey Manley, Nicole von Steinbuechel, Suzanne Polinder, Ewout W Steyerberg, Hester Lingsma
Persistent post-concussion symptoms (PPCS) occur frequently after mild traumatic brain injury (mTBI). The identification of patients at risk for poor outcome remains challenging since valid prediction models are missing. The objectives of the current study were to assess the quality and clinical value of prediction models for PPCS , and to develop a new model based on the synthesis of existing models and addition of complaints at emergency department (ED). MTBI patients (Glasgow Coma Scale score 13-15) were prospectively recruited from three Dutch level I trauma centers between 2013-2015 in the UPFRONT study...
April 25, 2018: Journal of Neurotrauma
https://www.readbyqxmd.com/read/29685463/a-prospective-evaluation-of-the-influence-of-an-electronic-clinical-practice-guidelines-on-concussion-patients-future-activities-and-outcomes
#13
Brian H Rowe, Leeor Eliyahu, Justin Lowes, Lindsay A Gaudet, Jeremy Beach, Martin Mrazik, Garnet Cummings, Donald Voaklander
BACKGROUND: Patients with mild traumatic brain injury or concussion commonly present to the emergency department for assessment; providing patients with information on usual symptoms and their progression may encourage faster recovery. OBJECTIVES: This study aimed to document the role of an electronic clinical practice guideline (eCPG) patient handout on concussion recovery in adult patients discharged from the hospital. METHODS: A prospective cohort study was carried out in 3 Canadian urban emergency departments...
April 20, 2018: Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29679852/accident-analysis-to-support-the-development-of-strategies-for-the-prevention-of-brain-injuries-in-car-crashes
#14
Jacobo Antona-Makoshi, Koji Mikami, Mats Lindkvist, Johan Davidsson, Sylvia Schick
This study estimated the frequency and risk of Moderate-to-Maximal traumatic brain injuries sustained by occupants in motor vehicle crashes in the US. National Automotive Sampling System - Crashworthiness Data System crashes that occurred in years 2001-2015 with light vehicles produced 2001 or later were incorporated in the study. Crash type, crash severity, car model year, belt usage and occupant age and sex were controlled for in the analysis. The results showed that Moderate concussions account for 79% of all MAISbrain 2+ injuries...
April 18, 2018: Accident; Analysis and Prevention
https://www.readbyqxmd.com/read/29678928/imaging-in-pediatric-concussion-a-systematic-review
#15
REVIEW
Julia Schmidt, Kathryn S Hayward, Katlyn E Brown, Jill G Zwicker, Jennie Ponsford, Paul van Donkelaar, Shelina Babul, Lara A Boyd
CONTEXT: Pediatric mild traumatic brain injury (mTBI) is a common and poorly understood injury. Neuroimaging may index brain injury and outcome after pediatric mTBI, but remains largely unexplored. OBJECTIVE: To investigate the differences in neuroimaging findings in children/youth with mTBI. Measures of behavior, symptoms, time since injury, and age at injury were also considered. DATA SOURCES: A systematic review was conducted up to July 6, 2016...
April 20, 2018: Pediatrics
https://www.readbyqxmd.com/read/29674994/a-cross-sectional-study-on-cerebral-hemodynamics-after-mild-traumatic-brain-injury-in-a-pediatric-population
#16
Corey M Thibeault, Samuel Thorpe, Michael J O'Brien, Nicolas Canac, Mina Ranjbaran, Ilyas Patanam, Artin Sarraf, James LeVangie, Fabien Scalzo, Seth J Wilk, Ramon Diaz-Arrastia, Robert B Hamilton
The microvasculature is prominently affected by traumatic brain injury (TBI), including mild TBI (concussion). Assessment of cerebral hemodynamics shows promise as biomarkers of TBI, and may help inform development of therapies aimed at promoting neurologic recovery. The objective of this study was to assess the evolution in cerebral hemodynamics observable with transcranial Doppler (TCD) ultrasound in subjects suffering from a concussion at different intervals during recovery. Pediatric subjects between the ages of 14 and 19 years clinically diagnosed with a concussion were observed at different points post-injury...
2018: Frontiers in Neurology
https://www.readbyqxmd.com/read/29674712/when-light-hurts-comparative-morphometry-of-human-brainstem-in-traumatic-photalgia
#17
Lora T Likova, Christopher W Tyler
Traumatic brain injury is an increasingly common affliction, although many of its serious repercussions are still underappreciated. A frequent consequence is the development of light-induced pain, or 'photalgia', which can often lead to prolonged debilitation. The mechanism underlying the sensitivity to light, however, remains unresolved. Since tissue oedema (swelling) is a common feature of traumatic brain injury, we propose that the brainstem oedema, in particular, might sensitize the brainstem trigeminal complex to signals from ocular mechanisms activated in bright light...
April 19, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29670568/the-dynamics-of-concussion-mapping-pathophysiology-persistence-and-recovery-with-causal-loop-diagramming
#18
Erin S Kenzie, Elle L Parks, Erin D Bigler, David W Wright, Miranda M Lim, James C Chesnutt, Gregory W J Hawryluk, Wayne Gordon, Wayne Wakeland
Despite increasing public awareness and a growing body of literature on the subject of concussion, or mild traumatic brain injury, an urgent need still exists for reliable diagnostic measures, clinical care guidelines, and effective treatments for the condition. Complexity and heterogeneity complicate research efforts and indicate the need for innovative approaches to synthesize current knowledge in order to improve clinical outcomes. Methods from the interdisciplinary field of systems science, including models of complex systems, have been increasingly applied to biomedical applications and show promise for generating insight for traumatic brain injury...
2018: Frontiers in Neurology
https://www.readbyqxmd.com/read/29665736/fear-avoidance-and-clinical-outcomes-from-mild-traumatic-brain-injury
#19
Noah D Silverberg, William Panenka, Grant L Iverson
Characterizing psychological factors that contribute to persistent symptoms after mild traumatic brain injury (MTBI) can inform early intervention. To determine whether fear avoidance, a known risk factor for chronic disability after musculoskeletal injury, is associated with worse clinical outcomes from MTBI, adults were recruited from four outpatient MTBI clinics and assessed at their first clinic visit (M=2.7, SD=1.5 weeks post-injury) and again 4-5 months later. Of 273 patients screened, 102 completed the initial assessment and 87 returned for the outcome assessment...
April 18, 2018: Journal of Neurotrauma
https://www.readbyqxmd.com/read/29660963/readiness-to-recognize-a-qualitative-case-study-of-educational-identification-of-tbi
#20
David Greene, Pat L Sample, Nicole Johns, Maureen Palmer
BACKGROUND: The educational identification (ED-ID) of students with traumatic brain injury (TBI) has been legislated in numerous states, and TBI has become its own special education category. Questions abound as to whether these changes will lead to more readily identifying these students to provide appropriate special education supports. OBJECTIVE: Elucidate one state's response to legislative changes around ED-ID of TBI. METHODS: This is a phenomenological case study of nine school districts in one state...
April 7, 2018: NeuroRehabilitation
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