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Sleep apnoea and women

Emilia Sforza, David Hupin, Vincent Pichot, Jean Claude Barthélémy, Frédéric Roche
BACKGROUND AND OBJECTIVE: Clinical and epidemiological cohort studies have shown that obstructive sleep apnoea (OSA) is a common but largely undiagnosed disorder in senior subjects, where progressive deterioration of the pathology would be expected as a consequence of the ageing processes. Our study examines the longitudinal progression of OSA over a 7-year period in a community-based sample of healthy subjects. METHODS: The sample consisted of 284 volunteers, aged >65 years (52% women, 48% men) accepting clinical and instrumental follow-up at 7 years...
February 22, 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
S W Knappe, M Bakke, P Svanholt, A Petersson, L Sonnesen
Patients with obstructive sleep apnoea (OSA) in long-term treatment with a mandibular advancement device (MAD) to increase the upper airway space may develop changes in the temporomandibular joint (TMJ) and the oro-facial function due to the protruded jaw position during sleep. The aim was to investigate the influence of long-term MAD treatment on the TMJs, oro-facial function and occlusion. This prospective study included 30 men and 13 women (median age 54) with OSA [Apnoea-Hypopnoea Index (AHI): 7-57]. They were examined with the Nordic Orofacial Test Screening (NOT-S), the Research Diagnostic Criteria for Temporomandibular Disorders (RDC/TMD) and cone beam computed tomography (CBCT) of the TMJs...
January 17, 2017: Journal of Oral Rehabilitation
Ken D O'Halloran, Philip Lewis, Fiona McDonald
Obstructive sleep apnoea syndrome (OSAS) is a devastating respiratory control disorder more common in men than women. The reasons for the sex difference in prevalence are multifactorial, but are partly attributable to protective effects of oestrogen. Indeed, OSAS prevalence increases in post-menopausal women. OSAS is characterized by repeated occlusions of the pharyngeal airway during sleep. Dysfunction of the upper airway muscles controlling airway calibre and collapsibility is implicated in the pathophysiology of OSAS, and sex differences in the neuro-mechanical control of upper airway patency are described...
November 21, 2016: Respiratory Physiology & Neurobiology
Thorarinn Gislason, Randi J Bertelsen, Francisco Gomez Real, Torben Sigsgaard, Karl A Franklin, Eva Lindberg, Christer Janson, Erna Sif Arnardottir, Johan Hellgren, Bryndis Benediktsdottir, Bertil Forsberg, Ane Johannessen
OBJECTIVE/BACKGROUND: Little is known about associations between traffic exposure and sleep disturbances. We examined if self-reported exposure to traffic is associated with habitual snoring and daytime sleepiness in a general population. METHODS: In the RHINE III study, 12184 adults answered questions on sleep disturbances and traffic exposure. We analysed bedrooms near roads with traffic, bedrooms with traffic noise, and travelling regularly along busy roads as proxies for traffic exposures, using logistic regression...
August 2016: Sleep Medicine
Vernon Min Sen Oh
According to the Singapore National Health Survey (NHS) of 2010, the population of the Republic of Singapore was 5.076,700, comprising four ethnic groups: Chinese (74.1%), Malays (13.4%), Indians (9.2%), and others (3.3%). The National Health Survey for 2016 is under way and due to be published in 2017. From the six-yearly national health surveys, the crude prevalence of clinical hypertension (HTn), defined as a sustained blood pressure ≥ 140/90 mmHg, in Singaporean residents aged 30 to 69 years rose from 22...
September 2016: Journal of Hypertension
Vernon Min Sen Oh
According to the Singapore National Health Survey (NHS) of 2010, the population of the Republic of Singapore was 5.076,700, comprising four ethnic groups: Chinese (74.1%), Malays (13.4%), Indians (9.2%), and others (3.3%). The National Health Survey for 2016 is under way and due to be published in 2017. From the six-yearly national health surveys, the crude prevalence of clinical hypertension (HTn), defined as a sustained blood pressure ≥ 140/90 mmHg, in Singaporean residents aged 30 to 69 years rose from 22...
September 2016: Journal of Hypertension
Jin Han, Ya Gao, Qi Guo, Dan Su, Bin Yan, Liyuan Peng, Yuxing Du, Ke Li, Gang Wang
OBJECTIVE: To investigate the relationship between the level of serum cystatin C (s-CC) and reverse-dipper blood pressure (BP) pattern. DESIGN: Cross-sectional study. SETTING: Single centre. PARTICIPANTS: A total of 718 hypertensive patients were eventually recruited from cardiac clinics between 2012 and 2014 in the Second Affiliated Hospital, Xi'an Jiaotong University. They were diagnosed as essential hypertension according to their casual office records of systolic blood pressure (SBP) and/or diastolic blood pressure (DBP)...
2016: BMJ Open
Alicia Sánchez-de-la-Torre, Jorge Abad, Joaquín Durán-Cantolla, Olga Mediano, Valentín Cabriada, María José Masdeu, Joaquín Terán, Juan Fernando Masa, Mónica de la Peña, Albina Aldomá, Fernando Worner, Joan Valls, Ferran Barbé, Manuel Sánchez-de-la-Torre
BACKGROUND: The cardiovascular consequences of obstructive sleep apnoea (OSA) differ by sex. We hypothesized that sex influences the severity of acute coronary syndrome (ACS) in patients with OSA. OSA was defined as an apnoea-hypopnoea index (AHI)>15 events·h-1. We evaluated the severity of ACS according to the ejection fraction, Killip class, number of diseased vessels, number of stents implanted and plasma peak troponin level. METHODS: We included 663 men (mean±SD, AHI 37±18 events·h-1) and 133 women (AHI 35±18 events·h-1) with OSA...
2016: PloS One
Nicolas Chudeau, Tommy Raveau, Laurence Carlier, Damien Leblanc, Guillaume Bouhours, Frédéric Gagnadoux, Emmanuel Rineau, Sigismond Lasocki
INTRODUCTION: The STOP-BANG (SB) questionnaire, a tool originally proposed for identifying patients at risk of obstructive sleep apnoea, may also identify patients at increased risk of perioperative complications (when>3). Perioperative complications, including respiratory ones, are more frequent in emergency surgery. This study aimed at evaluating whether the SB is predictive of perioperative respiratory complications in urgent surgery. METHODS: Consecutive adult patients admitted for an urgent surgery under general anaesthesia were included...
October 2016: Anaesthesia, Critical Care & Pain Medicine
Ingrid Dravecká
UNLABELLED: Polycystic ovary syndrome (PCOS) is a heterogeneous and complex endocrine disease which among the female population belongs to the most widespread endocrinopathies and it is the most frequent cause of hyperthyroidism, anticoagulation and infertility. Insulin resistance is one of the important diabetology factors impacting hyperglycaemia in a majority of women with PCOS (60-80 %). Clinical expressions of PCOS include reproduction disorders, metabolic characteristics and psychological implications...
2016: Vnitr̆ní Lékar̆ství
Jordan P R McIntyre, Cayley M Ingham, B Lynne Hutchinson, John M D Thompson, Lesley M McCowan, Peter R Stone, Andrew G Veale, Robin Cronin, Alistair W Stewart, Kevin M Ellyett, Edwin A Mitchell
BACKGROUND: The importance of maternal sleep and its contribution to maternal and fetal health during pregnancy is increasingly being recognised. However, the ability to accurately recall sleep practices during pregnancy has been questioned. The aim of this study is to test the accuracy of recall of normal sleep practices in late pregnancy. METHODS: Thirty healthy women between 35 and 38 weeks of gestation underwent level III respiratory polysomnography (PSG) with infrared digital video recordings in their own homes...
2016: BMC Pregnancy and Childbirth
Semra Mungan, Murat Ozcan, Gurdal Orhan, Ayse Titiz, Berna Arli, Sabri Koseoglu, Fikri Ak, Haci Huseyin Dere
OBJECTIVE: To reveal clinical and polysomnographic features in patients treated for restless leg syndrome, and to examine the compatibility of sleep data and clinical features. METHODS: The study was conducted at the Department of Neurology, Ankara Numune Training and Education Hospital, Ankara, Turkey, and comprised patients who presented to the outpatient clinic between January and July 2014 who were diagnosed with restless leg syndrome based on the International RestIess Leg Syndrome Study Group criteria...
May 2016: JPMA. the Journal of the Pakistan Medical Association
Cahit Bilgin, Unal Erkorkmaz, Muhammed Kursad Ucar, Nese Akin, Ahmet Nalbant, Ali Nihat Annakkaya
OBJECTIVE: Polysomnography (PSG) remains the gold standard for the diagnosis of obstructive sleep apnoea syndrome (OSAS). While PSG is essential for OSAS, this technique is not suitable for epidemiological investigation due to its high cost. This study aimed to compare a portable monitoring device with PSG for the measurement of parameters related to the diagnosis of OSAS in rural areas. METHODS: We conducted a descriptive study of 155 patients (30 women and 125 men; mean age, 52±12years) who visited to the Hendek Government Hospital Sleep Laboratory between February 2011 and January 2013 Apnoea hypopnea index (AHI), mean levels of O2 (meanO2), desaturation index (DI), and minimum oxygen saturation (minO2) variations as measured using both PSG and a portable Somnocheck Micro (SM) device were compared...
March 2016: Pakistan Journal of Medical Sciences Quarterly
Ahmed S BaHammam, Seithikurippu R Pandi-Perumal, Amanda Piper, Salman A Bahammam, Aljohara S Almeneessier, Awad H Olaish, Shahrokh Javaheri
The role of gender and menopause in obstructive sleep apnoea is well known; however, no study has reported the impact of gender on the clinical presentation and the nocturnal respiratory events in patients with obesity hypoventilation syndrome. Therefore, this study prospectively evaluated differences in the clinical characteristics of women and men with obesity hypoventilation syndrome in a large cohort of patients with obstructive sleep apnoea. During the study period, a total of 1973 patients were referred to the sleep clinic with clinical suspicion of obstructive sleep apnoea...
August 2016: Journal of Sleep Research
Sunita M C De Sousa, Robert J Norman
Polycystic ovary syndrome (PCOS) is associated with a range of metabolic complications including insulin resistance (IR), obesity, dyslipidaemia, hypertension, obstructive sleep apnoea (OSA) and non-alcoholic fatty liver disease. These compound risks result in a high prevalence of metabolic syndrome and possibly increased cardiovascular (CV) disease. As the cardiometabolic risk of PCOS is shared amongst the different diagnostic systems, all women with PCOS should undergo metabolic surveillance though the precise approach differs between guidelines...
November 2016: Best Practice & Research. Clinical Obstetrics & Gynaecology
Trygve Müller Jonassen, Tomas Mikal Eagan, Bjørn Bjorvatn, Sverre Lehmann
OBJECTIVES: To examine the prevalence of self-reported symptoms of obstructive sleep apnoea (OSA) in relation to asthma, respiratory symptoms, and pulmonary function. A secondary objective was to determine how sex impacted these relationships. METHODS: A random sample of all adults aged 47-48 and 71-73 years living in Bergen, Norway, were invited. Participants (3506, 69%) underwent spirometry testing and completed a questionnaire on sleep, respiratory symptoms, and past medical history...
March 7, 2016: Clinical Respiratory Journal
Francis Degache, Yannick Goy, Sopharat Vat, José Haba Rubio, Olivier Contal, Raphaël Heinzer
OBJECTIVE: Postural stability depends on the coordination of the central nervous system with visual sense, proprioceptive and vestibular information. Sleep deprivation has been shown to affect this function. The objective of our study was to assess the effects of sleep-disordered breathing (SDB) on postural stability. METHODS: 158 subjects referred for suspected SDB had an overnight sleep study and were placed on a posturographic platform in late afternoon. This platform allows measuring the centre of pressure (CoP) oscillations and to calculate: total displacement of CoP in X and Y axes, mean speed of CoP displacement and the length as function of surface (LFS) ratio (length of CoP displacement/surface of CoP trajectory)...
June 2016: Thorax
Maciej Rachwalik, Dorota Zyśko, Grzegorz Bielicki, Marta Obremska, Anna Goździk, Wojciech Kustrzycki
Surgical ablation is a recommended procedure for patients with atrial fibrillation (AF) undergoing a cardiac surgery operation. However, the procedure is associated with significant risk of late recurrence of AF. The aim of the study was to assess the long-term efficacy of the procedure with respect to the comorbidities. The study group consisted of 22 patients: 9 women and 13 men, who underwent surgical AF ablation in the 2008-2013 period. The patients were interviewed by telephone and were asked to send their recently performed 12-lead electrocardiography (ECG)...
December 2015: Kardiochirurgia i Torakochirurgia Polska, Polish Journal of Cardio-Thoracic Surgery
Yanping Li, Xiang Gao, John W Winkelman, Elizabeth M Cespedes, Chandra L Jackson, Arthur S Walters, Eva Schernhammer, Susan Redline, Frank B Hu
AIMS/HYPOTHESIS: Sleeping difficulty has been associated with type 2 diabetes in some prior studies. Whether the observed associations are independent of health behaviours, other cardiovascular risk factors or other sleep disorders is unclear. METHODS: We analysed data from 133,353 women without diabetes, cardiovascular disease and cancer at baseline in the Nurses' Health Study (NHS, 2000-2010) and the NHSII (2001-2011). Sleeping difficulty was assessed as having difficulty falling or staying asleep 'all of the time' or 'most of the time' at baseline (2000 in NHS and 2001 in NHSII)...
April 2016: Diabetologia
Babak Mokhlesi, Sandra A Ham, David Gozal
Obstructive sleep apnoea (OSA) is a highly prevalent condition but studies exploring the burden of OSA-associated comorbidities have been limited by small sample sizes with underrepresentation of women.We queried the Truven Health MarketScan Research Databases 2003-2012, which is a collection of health insurance claims for working adults and retirees with employer-sponsored health insurance. Adults with a diagnostic code for OSA with at least 12 months of follow-up from the index date of OSA diagnosis were compared to a matched random sample...
April 2016: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
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