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Proximal neuropathy

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https://www.readbyqxmd.com/read/27906945/ganglion-cyst-at-the-proximal-tibiofibular-joint-in-a-patient-with-painless-foot-drop
#1
Abdulmuhsen Alsahhaf, Waleed Renno
Entrapment neuropathies of the fibular nerve and its branches are often underdiagnosed due to the lack of reliable diagnosis using clinical examination and electrophysiologic evaluation. Most fibular nerve compressions may be classified into 2 broad categories: (a) mechanical causes, which occur at fibrous or fibro-osseous tunnels, and (b) dynamic causes related to nerve injury during specific limb positioning. Foot drop resulting from weakness of the dorsiflexor muscles of the foot is a relatively uncommon presentation and closely related to L5 neuropathy caused by a disc herniation...
November 2016: Pain Physician
https://www.readbyqxmd.com/read/27902538/ulnar-tunnel-syndrome-radial-tunnel-syndrome-anterior-interosseous-nerve-syndrome-and-pronator-syndrome
#2
Adam B Strohl, David S Zelouf
In addition to the more common carpal tunnel and cubital tunnel syndromes, orthopaedic surgeons must recognize and manage other potential sites of peripheral nerve compression. The distal ulnar nerve may become compressed as it travels through the wrist, which is known as ulnar tunnel or Guyon canal syndrome. The posterior interosseous nerve may become entrapped in the proximal forearm as it travels through the radial tunnel, which results in a pain syndrome without motor weakness. The median nerve may become entrapped in the proximal forearm, which can result in a variety of symptoms...
November 29, 2016: Journal of the American Academy of Orthopaedic Surgeons
https://www.readbyqxmd.com/read/27900300/treatment-of-proximal-hamstring-tendinopathy-related-sciatic-nerve-entrapment-presentation-of-an-ultrasound-guided-intratissue-percutaneous-electrolysis-application
#3
Gabriele Mattiussi, Carlos Moreno
BACKGROUND: Proximal Hamstring Tendinopathy-related Sciatic Nerve Entrapment (PHTrSNE) is a neuropathy caused by fibrosis interposed between the semimembranosus tendon and the sciatic nerve, at the level of the ischial tuberosity. METHODS: Ultrasound-guided Intratissue Percutaneous Electrolysis (US-guided EPI) involves galvanic current transfer within the treatment target tissue (fibrosis) via a needle 0.30 to 0.33 mm in diameter. The galvanic current in a saline solution instantly develops the chemical process of electrolysis, which in turn induces electrochemical ablation of fibrosis...
April 2016: Muscles, Ligaments and Tendons Journal
https://www.readbyqxmd.com/read/27882360/static-and-dynamic-predictors-of-foot-progression-angle-in-individuals-with-and-without-diabetes-mellitus-and-peripheral-neuropathy
#4
Ericka N Merriwether, Mary K Hastings, Michael J Mueller, Kathryn L Bohnert, Michael J Strube, Darrah R Snozek, David R Sinacore
INTRODUCTION: Foot progression angle (FPA) is a predictor of elevated regional plantar stresses and loads, which are indicators of dermal injury risk in individuals with diabetes mellitus and peripheral neuropathy (DMPN). FPA accounts for 15-45% of the variance in plantar stresses and loads in adults with DMPN. However, the biomechanical factors underlying an "out-toeing" gait pattern in this clinical population have not been examined. The primary purpose of this study was to identify static and dynamic predictors of foot progression angle magnitude in adults with and without DMPN...
2016: Annals of Gerontology and Geriatric Research
https://www.readbyqxmd.com/read/27857636/posterior-lateral-and-anterior-hip-pain-due-to-musculoskeletal-origin-a-narrative-literature-review-of-history-physical-examination-and-diagnostic-imaging
#5
REVIEW
Patrick J Battaglia, Kevin D'Angelo, Norman W Kettner
OBJECTIVE: The purpose of this study was to present a narrative review of the literature of musculoskeletal causes of adult hip pain, with special attention to history, physical examination, and diagnostic imaging. METHODS: A narrative review of the English medical literature was performed by using the search terms "hip pain" AND "anterior," "lateral," and "posterior." Additionally, specific entities of hip pain or pain referral sources to the hip were searched for...
December 2016: Journal of Chiropractic Medicine
https://www.readbyqxmd.com/read/27855765/-pronator-teres-syndrome-is-a-rare-but-important-cause-of-pain-in-the-forearm
#6
Mathias Bæk Rasmussen, Søren Rasmussen Deutch
Pronator teres syndrome is a rare but clinically important condition which can cause pain in the forearm. It is a com-pression neuropathy due to compression of the median nerve proximal in the forearm. In this case report we de-scribe a 69-year-old male patient with pain in both forearms in more than ten years. After surgical decompression of the median nerve in both arms he experienced almost complete relief of his symptoms.
November 14, 2016: Ugeskrift for Laeger
https://www.readbyqxmd.com/read/27843079/morphology-and-morphometry-of-the-ulnar-head-of-the-pronator-teres-muscle-in-relation-to-median-nerve-compression-at-the-proximal-forearm
#7
I A Gurses, L Altinel, O Gayretli, T Akgul, I Uzun, F Dikici
INTRODUCTION: The pronator syndrome is a rare compression neuropathy of the median nerve. Ulnar head of the pronator teres muscle may cause compression at proximal forearm. HYPOTHESIS: Detailed morphologic and morphometric studies on the anatomy of the ulnar head of pronator teres is scarce. MATERIAL AND METHODS: We dissected 112 forearms of fresh cadavers. We evaluated the morphology and morphometry of the ulnar head of pronator teres muscle...
November 11, 2016: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/27797810/prevention-of-vincristine-induced-peripheral-neuropathy-by-genetic-deletion-of-sarm1-in-mice
#8
Stefanie Geisler, Ryan A Doan, Amy Strickland, Xin Huang, Jeffrey Milbrandt, Aaron DiAntonio
Peripheral polyneuropathy is a common and dose-limiting side effect of many important chemotherapeutic agents. Most such neuropathies are characterized by early axonal degeneration, yet therapies that inhibit this axonal destruction process do not currently exist. Recently, we and others discovered that genetic deletion of SARM1 (sterile alpha and TIR motif containing protein 1) dramatically protects axons from degeneration after axotomy in mice. This finding fuels hope that inhibition of SARM1 or its downstream components can be used therapeutically in patients threatened by axonal loss...
December 2016: Brain: a Journal of Neurology
https://www.readbyqxmd.com/read/27763908/ultrasonographic-and-surgical-findings-of-acute-radial-neuropathy-following-blunt-trauma
#9
Seok-Youl Choi, Jong Woong Park, Dong Hwee Kim
Ultrasonographic study is useful for decision making of treatment for focal neuropathy with unusual electrodiagnostic findings. We present a patient with severe acute radial neuropathy with sensory sparing around the distal arm secondary to twisting of the radial nerve following blunt trauma. A 24-year-old man with a 2-week history of left wrist drop and severe pain around the left elbow presented after hitting the left distal arm on the doorknob. The left wrist and finger extensions were grade 0, but elbow extension could not be tested because of severe pain during this action...
November 2016: American Journal of Physical Medicine & Rehabilitation
https://www.readbyqxmd.com/read/27683851/posterior-interosseous-neuropathy-supinator-syndrome-vs-fascicular-radial-neuropathy
#10
Philipp Bäumer, Henrich Kele, Annie Xia, Markus Weiler, Daniel Schwarz, Martin Bendszus, Mirko Pham
OBJECTIVE: To investigate the spatial pattern of lesion dispersion in posterior interosseous neuropathy syndrome (PINS) by high-resolution magnetic resonance neurography. METHODS: This prospective study was approved by the local ethics committee and written informed consent was obtained from all patients. In 19 patients with PINS and 20 healthy controls, a standardized magnetic resonance neurography protocol at 3-tesla was performed with coverage of the upper arm and elbow (T2-weighted fat-saturated: echo time/repetition time 52/7,020 milliseconds, in-plane resolution 0...
November 1, 2016: Neurology
https://www.readbyqxmd.com/read/27666943/disease-characteristics-and-electromyographic-findings-of-nonsurgery-related-unilateral-vocal-fold-paralysis
#11
Yu-Cheng Pei, Hsueh-Yu Li, Cheng-Lun Chen, Alice M K Wong, Pei-Chi Huang, Tuan-Jen Fang
OBJECTIVE: The detailed characteristics and prognosis of nonsurgery-related unilateral vocal fold paralysis (NSUVFP) are currently unclear. This study evaluated the extent of laryngeal nerve lesions and the individual characteristics for patients with NSUVFP. STUDY DESIGN: Retrospective, case series. METHODS: Patients with unilateral vocal fold paralysis (UVFP) were evaluated using videolaryngostroboscopy and quantitative laryngeal electromyography...
September 26, 2016: Laryngoscope
https://www.readbyqxmd.com/read/27648065/an-unusual-cause-of-foot-drop-peroneal-extraneural-ganglion-cyst
#12
Murat Zumrut, Mehmet Demirayak, Ahmet Kucukapan
Peripheral neuropathies caused by ganglion cysts are quite rare, especially in the lower extremities. The case of a 64-year-old male with a 2-day history of foot drop and tenderness in the region of the left fibular neck is presented. Physical examination and electromyogram findings verified peroneal nerve palsy. Ultrasonography showed cystic mass localized proximal of the peroneal muscle structures. Magnetic resonance imaging revealed a cystic-appearing mass around the fibular neck that compressed the common peroneal nerve...
July 2016: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/27643671/evaluation-of-the-tibial-nerve-with-shear-wave-elastography-a-potential-sonographic-method-for-the-diagnosis-of-diabetic-peripheral-neuropathy
#13
Atilla Suleyman Dikici, Fethi Emre Ustabasioglu, Sakir Delil, Mecbure Nalbantoglu, Bektas Korkmaz, Selim Bakan, Osman Kula, Nurten Uzun, Ismail Mihmanli, Fatih Kantarci
Purpose To evaluate the value of shear-wave elastography (SWE) in the detection of diabetic peripheral neuropathy (DPN) of the tibial nerve. Materials and Methods This study was approved by the institutional review board, and written informed consent was obtained from all study participants. The study included 20 diabetic patients with DPN (10 men, 10 women), 20 diabetic patients without DPN (eight men, 12 women), and 20 healthy control subjects (nine men, 11 women). The tibial nerve was examined at 4 cm proximal to the medial malleolus with gray-scale ultrasonography and SWE...
September 19, 2016: Radiology
https://www.readbyqxmd.com/read/27617106/progressive-foot-drop-caused-by-below-knee-compression-stocking-after-spinal-surgery
#14
Karan Malhotra, Joseph S Butler, Adam Benton, Sean Molloy
Foot drop is a debilitating condition, which may take many months to recover. The most common cause of foot drop is a neuropathy of the common peroneal nerve (CPN). However, similar symptoms can be caused by proximal lesions of the sciatic nerve, lumbar plexus or L5 nerve root. We present a rare and unusual case of a patient undergoing spinal surgery at the level of L5/S1 and presenting 4 weeks postoperatively with progressive foot drop. Although the initial concern was a postoperative lesion at L5, the cause for this delayed presentation was extrinsic compression of the CPN at the level of the fibular head by a tight-fitting below-knee thromboembolic deterrent stocking...
September 2016: Oxford Medical Case Reports
https://www.readbyqxmd.com/read/27562829/type-a-ganglion-cysts-of-the-radiocapitellar-joint-may-involve-compression-of-the-superficial-radial-nerve
#15
J Rodriguez Miralles, L Natera Cisneros, A Escolà, J C Fallone, M Cots, X Espiga
INTRODUCTION: Two types of ganglion cysts at the elbow have been described depending on their anatomic location. Type A ganglion cyst is located proximal to the arcade of Frohse, and type B distal to it. Compressive neuropathies of the radial nerve at the level of the radial tunnel may lead to two different clinical entities with different clinical manifestations. These different conditions depend on which branch is involved. Although compression of the deep motor branch due to a ganglion cyst has been previously described, affection of the superficial sensory branch is considered much rarer...
October 2016: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/27560494/sur1-associated-mechanisms-are-not-involved-in-ischemic-optic-neuropathy-1-day-post-injury
#16
James D Nicholson, Yan Guo, Steven L Bernstein
Ischemia-reperfusion injury after central nervous system (CNS) injury presents a major health care challenge with few promising treatments. Recently, it has become possible to reduce edema after CNS injury by antagonizing a sulfonylurea receptor 1 (SUR1) regulated ion channel expressed after injury. SUR1 upregulation after injury is a necessary precondition for the formation of this channel, and has been implicated in white matter injury after clinical spinal cord trauma. Glibenclamide, an SUR1 antagonist, appears to have neuroprotective effect against cerebral stroke in an open-label small clinical trial and great effectiveness in reducing damage after varied experimental CNS injury models...
2016: PloS One
https://www.readbyqxmd.com/read/27536494/a-proximally-based-sural-fasciocutaneous-flap-for-the-treatment-of-recurrent-peroneal-neuropathy-a-case-report
#17
Souichi Ohta, Ryosuke Ikeguchi, Takashi Noguchi, Yukitoshi Kaizawa, Hiroki Oda, Shuichi Matsuda
Surgical treatment for recurrent, common peroneal neuropathy has not been reported. Herein, we describe a successfully treated case using the proximally based sural fasciocutaneous flap after reneurolysis of the adhesive common peroneal nerve. A 33-year-old man received a neurolysis operation for entrapment neuropathy of the common peroneal nerve 2 years before first admission in our clinic. Although motor nerve conduction studies showed a marked improvement after the primary operation, the patient always required the use of a crutch because of severe pain radiating to the lower leg during standing or walking...
July 2016: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/27517075/extensive-osteochondroma-of-talus-presenting-as-tarsal-tunnel-syndrome-report-of-a-case-and-literature-review
#18
Shishir Suranigi, Kanagasabai Rengasamy, Syed Najimudeen, James Gnanadoss
Osteochondroma or exostosis is the most common benign bone tumor, and occurring frequently in the proximal humerus, tibia, and distal femur. It rarely affects talus. Osteochondroma of talus is a very rare etiology of tarsal tunnel syndrome (TTS). We report a rare case of extensive osteochondroma of the talus in a 60 year old female presenting with multiple swellings around the ankle and symptoms suggestive of tarsal tunnel syndrome. En-block excision of the multiple masses was done. Histopathological examination confirmed the diagnosis of osteochondroma...
June 2016: Archives of Bone and Joint Surgery
https://www.readbyqxmd.com/read/27494058/differential-diagnosis-and-intervention-of-proximal-median-nerve-entrapment-a-resident-s-case-problem
#19
Marcus R Bair, Michael T Gross, Jennifer R Cooke, Carla H Hill
Study Design Resident's case problem. Background Entrapment neuropathies represent a diagnostic challenge and require a comprehensive understanding of the nerve's path and the anatomical structures that may cause compression of the nerve. This resident's case problem details the evaluation and differential diagnosis process for median nerve entrapment resulting from forceful and repetitive pronation/supination motions. Diagnosis Median nerve compression syndromes include pronator syndrome, anterior interosseous nerve syndrome, and carpal tunnel syndrome...
September 2016: Journal of Orthopaedic and Sports Physical Therapy
https://www.readbyqxmd.com/read/27488522/structural-basis-for-induction-of-peripheral-neuropathy-by-microtubule-targeting-cancer-drugs
#20
Jennifer A Smith, Barbara S Slusher, Krystyna M Wozniak, Mohamed H Farah, Gregoriy Smiyun, Leslie Wilson, Stuart Feinstein, Mary Ann Jordan
Peripheral neuropathy is a serious, dose-limiting side effect of cancer treatment with microtubule-targeting drugs. Symptoms present in a "stocking-glove" distribution, with longest nerves affected most acutely, suggesting a length-dependent component to the toxicity. Axonal transport of ATP-producing mitochondria along neuronal microtubules from cell body to synapse is crucial to neuronal function. We compared the effects of the drugs paclitaxel and ixabepilone that bind along the lengths of microtubules and the drugs eribulin and vincristine that bind at microtubule ends, on mitochondrial trafficking in cultured human neuronal SK-N-SH cells and on axonal transport in mouse sciatic nerves...
September 1, 2016: Cancer Research
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