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Lumbar chronic pain

Saru Singh, Kulvinder Singh, Ruchi Gupta, Nayyamat Kaur, Pranav Bansal, Sanjeet Singh
CONTEXT AND AIM: The assessment of severity of low back pain includes subjective questionnaires to quantify the impact on routine life. The objective of current study was to correlate various quality of life (QOL) scores to the clinical outcome measured as improvement in Visual Analog Score (VAS) after interventional treatment. SUBJECTS AND METHODS: Fifty-one consecutive chronic low backache patients were assessed for pain intensity using VAS, revised Oswestry Disability Index (ODI), Quebec's, Roland-Morris disability questionnaire (RMDQ), and depression score at presentation...
September 2016: Anesthesia, Essays and Researches
Carol Ann Flavell, Susan Gordon, Laurence Marshman
BACKGROUND: Physiotherapists use musculo-skeletal classification systems for patient assessment. Since its early development, the McKenzie lumbar spine assessment (MK) has been incorporated into examination algorithms and combined with a series of patho-anatomical diagnostic tests. No previous studies have used a MK and a combined examination (MK-C) to provide a detailed profile of patients, report and compare the classification characteristics of a chronic low back pain (CLBP) population...
October 5, 2016: Manual Therapy
Zhuofeng Ding, Wei Xu, Jie Zhang, Wangyuan Zou, Qulian Guo, Changsheng Huang, Chang Liu, Tao Zhong, Jun-Ming Zhang, Zongbin Song
Bone cancer pain (BCP) is the most common complication in patients with bone cancer. Glial cell line-derived neurotrophic factor (GDNF) is believed to be involved in chronic pain conditions. In this article, the expression and roles of GDNF were studied in a rat model of BCP induced by tibia injection of Walker 256 rat mammary gland carcinoma cells. Significant mechanical and thermal hyperalgesia and ongoing pain were observed beginning as early as day 5 post injection. The expression level of GDNF protein examined on day 16 after tibia injection was decreased in the L3 dorsal root ganglion (DRG) and lumbar spinal cord, but not in other spinal levels or the anterior cingulate cortex...
September 22, 2016: International Journal of Cancer. Journal International du Cancer
J J Wong, P Côté, D A Sutton, K Randhawa, H Yu, S Varatharajan, R Goldgrub, M Nordin, D P Gross, H M Shearer, L J Carroll, P J Stern, A Ameis, D Southerst, S Mior, M Stupar, T Varatharajan, A Taylor-Vaisey
: We conducted a systematic review of guidelines on the management of low back pain (LBP) to assess their methodological quality and guide care. We synthesized guidelines on the management of LBP published from 2005 to 2014 following best evidence synthesis principles. We searched MEDLINE, EMBASE, CINAHL, PsycINFO, Cochrane, DARE, National Health Services Economic Evaluation Database, Health Technology Assessment Database, Index to Chiropractic Literature and grey literature. Independent reviewers critically appraised eligible guidelines using AGREE II criteria...
October 6, 2016: European Journal of Pain: EJP
Max Stuelcken, Daniel Mellifont, Adam Gorman, Mark Sayers
The wrist/hand complex forms the crucial final link in the kinetic chain between the body and the racquet and therefore has a number of important roles in the production of all tennis strokes. However, the internal and external loads that are created at the wrist during these strokes have the potential to contribute to pain and injury. Therefore, the purposes of this narrative review are to (1) determine the extent of the problem of wrist pain/injury in tennis players, (2) identify bony and soft tissue structures of the wrist that are susceptible to damage as a result of tennis play and (3) explore factors that may influence the development of wrist pain/injury in tennis players...
October 3, 2016: Sports Medicine
Hongbin Jia, Shuangshuang Xu, Qingzhen Liu, Jian Liu, Jianguo Xu, Weiyan Li, Yi Jin, Qing Ji
The molecular mechanisms underlying neuropathic pain have yet to be elucidated. The present study aimed to examine the modulation of neuroimmune activation in the spinal cord by the synthetic peroxisome proliferator-activated receptor gamma (PPAR-γ) agonist, pioglitazone (Pio), in a rat model of neuropathic pain induced by chronic constriction injury (CCI). Rats were randomly assigned into four groups: Sham surgery with vehicle, chronic constriction injury with vehicle or Pio (10 mg/kg), and chronic constriction injury with Pio and a PPAR-γ antagonist GW9662 (2 mg/kg)...
October 2016: Experimental and Therapeutic Medicine
Serbülent Gökhan Beyaz
STUDY DESIGN: A cross-sectional study. OBJECTIVE: we compared the 12 month outcomes of fluoroscopically guided transforaminal epidural steroid injections with interlaminar epidural steroid injections for the treatment of chronic lumbar spinal pain. Chronic lower back pain is a multifactorial disorder with many possible etiologies. The lifetime prevalence of spinal pain is reportedly 65-80% in the neck and lower back. Epidural injection of corticosteroids is a commonly used intervention for managing chronic spinal pain...
September 30, 2016: Revista Brasileira de Anestesiologia
Alan T Villavicencio, E Lee Nelson, Vinod Kantha, Sigita Burneikiene
OBJECTIVE Opioid analgesics have become some of the most prescribed drugs in the world, despite the lack of long-term studies evaluating the benefits of opioid medications versus their risks associated with chronic use. In addition, long-term opioid use may be associated with worse long-term clinical outcomes. The primary objective of this study was to evaluate whether preoperative opioid use predicted inferior clinical outcomes among patients undergoing transforaminal lumbar interbody fusion (TLIF) for symptomatic lumbar degenerative disc disease...
September 30, 2016: Journal of Neurosurgery. Spine
Mario G Zotti, Oscar P Brumby-Rendell, Ben McDonald, Tom Fisher, Christovalantis Tsimiklis, Wai Weng Yoon, Orso L Osti
BACKGROUND: Our aim was to determine whether patients derived benefit from removal of pedicle screw instrumentation for axial pain without other cause using our surgical technique and patient selection. A secondary aim was to investigate factors that were associated with poorer outcomes for this procedure as well as complication rate in this cohort. METHODS: Theater records from a single spinal surgeon's practice were reviewed to identify patients that had undergone lumbar fusion for discogenic back pain with subsequent pedicle screw instrumentation removal (Expedium, DePuy Synthes) in the preceding 3 years with a minimum of 18 months follow-up...
December 2015: J Spine Surg
Germain Maberou Houngbedji, Etienne Alagnide, Didier Niama, Fiacre Akpogan, Toussaint G Kpadonou
OBJECTIVE: To analyse the characteristic of back pain in schooled adolescents in the municipality of Cotonou. MATERIAL/PATIENTS AND METHODS: This is a prospective descriptive and analytic study of 334 schooled adolescents in the municipality of Cotonou from March 30 to June 30, 2015. RESULTS: The mean age of the adolescents was 16.96±0.18 years with a female predominance of 55.98% (sex ratio=0.71). Back pain was founded in 42.51% of respondents...
September 2016: Annals of Physical and Rehabilitation Medicine
Emmanuelle Chaleat-Valayer, Agnès Troncy, Marion Montané, Soline Bellaiche, Eric Berthonnaud
OBJECTIVE: The goal of this preliminary study is to analyze the biomechanical strategies of spine, pelvis and lower limbs (LL) with tridimensional motion analysis during stand-to-sit task, an understudied movement in the literature, however, source of questioning in clinical practice. OBSERVATIONS: One female and one male, healthy participants, (respectively 28 and 48 years old) were included without history of pathology and with normal pelvic incidences. Participants performed stand-to-sit movements on a stool without using their hands...
September 2016: Annals of Physical and Rehabilitation Medicine
Clémence Coll, Elsa Mauruc, Célia Valser, Luce Condamine, Emilie Hutin, Yves Coulomb, Jean-Michel Gracies, Shahab Fardjad
OBJECTIVE: The efficacy of multidisciplinary functional restoration spine programs (FRP) has been demonstrated in terms of secondary prevention in chronic low-back pain (LBP), working lumbar spine reconditioning. Our LBP patients follow a FRP program, one day/week over 5 weeks, with self-rehabilitation the other days called "mini FRP". The objective of the study is to compare responses to a mini-FRP program, between two groups from a population of patients working with LBP: "Sedentary Workers (SW)" and "Force Workers (FW)"...
September 2016: Annals of Physical and Rehabilitation Medicine
Charlotte Lanhers, Laura Boutevillain, Bruno Pereira, Emmanuel Coudeyre
OBJECTIVE: We aimed to evaluate the place of lumbar support in the management of nonspecific low back pain. MATERIAL AND METHODS: We conducted a systematic review with the following databases: Pubmed, Cochrane Library, Science Direct and Pedro. The search strategy used the keywords low back pain; lumbar orthosis; lumbar belt; back support; lumbar support; lumbar brace. To be included, studies needed to have one or more keywords selected. The search was limited to French and English articles...
September 2016: Annals of Physical and Rehabilitation Medicine
Jérôme Molimard, Rebecca Bonnaire, Reynald Convert, Woo Suck Han, Paul Calmels
OBJECTIVE: Although it is only a part of their therapeutic effect, the mechanical effect of compression or contention medical devices (CCMD) is always claimed by the manufacturers. However, the mechanism between the pressure application zone and the targeted organ is complex. It involves a purely passive mechanical effect and mechanisms related to the tonic postural system. Various strategies can be implemented to show the effectiveness of a mechanical action; among them, biomechanical modeling is a able to consider complex mechanical effects before any clinical trial...
September 2016: Annals of Physical and Rehabilitation Medicine
Mathilde Berger, Alessandro Farné, Karen Reilly, Emmanuelle Chaléat-Valayer
OBJECTIVE/INTRODUCTION: The body image refers to the conscious representation of our own body. It can be modulated by various sensory manipulations and can also be disturbed in people with chronic pain [1,2]. OBJECTIVE: The objective of this study is to assess the body image of people with chronic low back pain (CLBP) and its evolution after a functional restoration program (FRP). MATERIAL/PATIENTS AND METHODS: Prospective and single-center study, carried out on a population of people with CLBP receiving a FRP lasting four weeks...
September 2016: Annals of Physical and Rehabilitation Medicine
Arnaud Dupeyron, Matthias Toulotte, Sophie Bastide, Sandrine Alonso, Emmanuel Coudeyre
OBJECTIVE: Fears and beliefs play a key role in the development of low back pain according to the biopsychosocial model without specific tool in French. The Back and Beliefs Questionnaire (BBQ) is a validated self-administered questionnaire, allowing to detect the presence of false beliefs related to lumbar disease and that can guide therapeutic management. The objectives of this study were to (i) translate, (ii) validate the BBQ in French, (iii) and compare results with published validations...
September 2016: Annals of Physical and Rehabilitation Medicine
Teng Maëlys, Gilberte Robain, Samy Bendaya
OBJECTIVE: Sacral neuromodulation is usually used to treat non-obstructive urinary retention when other forms of treatment have failed. An improvement greater than 50% in urinary symptoms after 40months of follow-up has been shown: - moreover, it also has few complications: infections, technical failures, discomfort; - we report a case of dystonia of the lower limb, appeared after sacral neuromodulation implantation. OBSERVATIONS: MMP is a 16-year-old boy with early puberty as noteworthy medical history...
September 2016: Annals of Physical and Rehabilitation Medicine
Dorien Goubert, Jessica Van Oosterwijck, Mira Meeus, Lieven Danneels
BACKGROUND: Lumbar muscle dysfunction due to pain might be related to altered lumbar muscle structure. Macroscopically, muscle degeneration in low back pain (LBP) is characterized by a decrease in cross-sectional area and an increase in fat infiltration in the lumbar paraspinal muscles. In addition microscopic changes, such as changes in fiber distribution, might occur. Inconsistencies in results from different studies make it difficult to draw firm conclusions on which structural changes are present in the different types of non-specific LBP...
September 2016: Pain Physician
Michael F Coscia, Gerald A Denys, Matthew F Wack
STUDY DESIGN: Patients scheduled for spinal surgery were screened prospectively for a microbial presence associated with intervertebral disc specimens. Inclusion was limited to patients requiring surgery for any of 5 conditions: study patients with cervical spine intervertebral herniation (IVH), lumbar spine IVH, lumbar spine discogenic pain, and control patients with idiopathic scoliosis/Scheurermann's kyphosis or trauma/neuromuscular deformity. Exclusion criteria included ongoing systemic infection, abnormal pre-operative white cell counts, documented or suspected spinal infection, or previous surgery to the involved disc...
September 23, 2016: Spine
David C Noriega, Francisco Ardura, Ruben Hernández-Ramajo, Miguel Angel Martín-Ferrero, Israel Sánchez-Lite, Borja Toribio, Mercedes Alberca, Veronica García, José Maria Moraleda, Ana Sánchez, Javier García-Sancho
BACKGROUND: Degenerative disc disease often causes severe low-back pain, a public health problem with huge economic and life quality impact. Chronic cases often require surgery, which may lead to biomechanical problems and accelerated degeneration of the adjacent segments. Autologous mesenchymal stromal cells (MSC) treatments have shown feasibility, safety and strong indications of clinical efficacy. We present here a randomized, controlled trial using allogeneic MSC, which are logistically more convenient than autologous cells...
September 21, 2016: Transplantation
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